GGACT domain-containing protein

Overview
NameGGACT domain-containing protein
Smed IDSMED30011479
Length (bp)1052
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of GGACT domain-containing protein (SMED30011479) t-SNE clustered cells

Violin plots show distribution of expression levels for GGACT domain-containing protein (SMED30011479) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of GGACT domain-containing protein (SMED30011479) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for GGACT domain-containing protein (SMED30011479) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30011479

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 48

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30011479h1SMcG0005350 Contig2500GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30011479h1SMcG0005355 Contig2500GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30011479h1SMcG0021353 Contig2500GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30011479h1SMcG0005350 Contig2500GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30011479h1SMcG0005355 Contig2500GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30011479h1SMcG0021353 Contig2500GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30011479h1SMcG0005350 Contig2500GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30011479h1SMcG0005355 Contig2500GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30011479h1SMcG0021353 Contig2500GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
protonephridiaSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30011479h1SMcG0005350 dd_Smed_v4_7000_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30011479h1SMcG0005350 dd_Smed_v4_7000_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30011479h1SMcG0005350 dd_Smed_v4_7000_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30011479h1SMcG0005350 dd_Smed_v4_7000_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30011479h1SMcG0005350 dd_Smed_v4_7000_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30011479h1SMcG0005350 dd_Smed_v4_7000_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30011479h1SMcG0005356 dd_Smed_v4_2109_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30011479h1SMcG0005350 dd_Smed_v4_7000_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30011479h1SMcG0005350 dd_Smed_v4_7000_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30011479h1SMcG0005350 dd_Smed_v4_7000_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pigment cellSMED30011479h1SMcG0005356 dd_Smed_v6_2109_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
glial cellSMED30011479h1SMcG0005356 dd_Smed_v6_2109_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pigment cellSMED30011479h1SMcG0005356 dd_Smed_v6_2109_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
glial cellSMED30011479h1SMcG0005356 dd_Smed_v6_2109_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pigment cellSMED30011479h1SMcG0005356 dd_Smed_v6_2109_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
glial cellSMED30011479h1SMcG0005356 dd_Smed_v6_2109_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
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BLAST of GGACT domain-containing protein vs. Ensembl Human
Match: GGACT (gamma-glutamylamine cyclotransferase [Source:HGNC Symbol;Acc:HGNC:25100])

HSP 1 Score: 76.6406 bits (187), Expect = 3.094e-16
Identity = 51/145 (35.17%), Postives = 73/145 (50.34%), Query Frame = 2 
Query:   86 SFLFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLCLAE--------SDENP-KTEYLCYTYXXXXXXXXXXXXXXXDDYSSK-VHG 490
            + +F YGTLK  + N H + +        F A G   E YPLV+    N+P+LL + G G+ V+GE++ + D + L F DDFE CP  Y+R +   +        ++E P  T   C+ Y    F PE   LP  D Y S+  HG
Sbjct:    2 ALVFVYGTLKRGQPN-HRVLRDGAHGSAAFRARGRTLEPYPLVIAGEHNIPWLLHLPGSGRLVEGEVYAV-DERMLRFLDDFESCPALYQRTVLRVQLLEDRAPGAEEPPAPTAVQCFVYSRATFPPEWAQLPHHDSYDSEGPHG 144
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Human
Match: GGACT (gamma-glutamylamine cyclotransferase [Source:HGNC Symbol;Acc:HGNC:25100])

HSP 1 Score: 76.6406 bits (187), Expect = 3.094e-16
Identity = 51/145 (35.17%), Postives = 73/145 (50.34%), Query Frame = 2 
Query:   86 SFLFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLCLAE--------SDENP-KTEYLCYTYXXXXXXXXXXXXXXXDDYSSK-VHG 490
            + +F YGTLK  + N H + +        F A G   E YPLV+    N+P+LL + G G+ V+GE++ + D + L F DDFE CP  Y+R +   +        ++E P  T   C+ Y    F PE   LP  D Y S+  HG
Sbjct:    2 ALVFVYGTLKRGQPN-HRVLRDGAHGSAAFRARGRTLEPYPLVIAGEHNIPWLLHLPGSGRLVEGEVYAV-DERMLRFLDDFESCPALYQRTVLRVQLLEDRAPGAEEPPAPTAVQCFVYSRATFPPEWAQLPHHDSYDSEGPHG 144
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Celegans
Match: F42A10.9 (pep chromosome:WBcel235:III:6164645:6171165:1 gene:WBGene00023489.1 transcript:F42A10.9.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F42A10.9)

HSP 1 Score: 75.0998 bits (183), Expect = 4.230e-16
Identity = 38/90 (42.22%), Postives = 60/90 (66.67%), Query Frame = 2 
Query:   92 LFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERK 361
            +F YGTLK+ E N+  +S+     E +F+++G   EK+PLVVG++ N+PFLLD  G G N++GE++++ + K L   D+ E  P  Y+RK
Sbjct:    7 VFVYGTLKTGEPNYKVLSE--TDGEYRFISSGTTVEKFPLVVGTKYNIPFLLDDAGNGNNIEGEMYEVCEKK-LKVLDELEAYPTLYDRK 93
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Fly
Match: CG2811 (gene:FBgn0035082 transcript:FBtr0072412)

HSP 1 Score: 74.7146 bits (182), Expect = 6.905e-16
Identity = 41/103 (39.81%), Postives = 62/103 (60.19%), Query Frame = 2 
Query:   83 TSFLFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYER--KLCLAESDE 385
             + +F YGTLK  E N H+++K  E  + +F+  G    K+PLVVG+R N+PFLL   G G +++GE++++ D   L   D  ED P YY+R  +  L E +E
Sbjct:    8 AARVFVYGTLKRGEPNHHWLTK-KENGQARFLGRGKTETKFPLVVGTRYNIPFLLARPGEGNHIEGEVYEV-DETMLSKLDILEDYPDYYDREQQTILMEQNE 108
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Fly
Match: CG2811 (gene:FBgn0035082 transcript:FBtr0345515)

HSP 1 Score: 74.3294 bits (181), Expect = 9.044e-16
Identity = 41/103 (39.81%), Postives = 62/103 (60.19%), Query Frame = 2 
Query:   83 TSFLFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYER--KLCLAESDE 385
             + +F YGTLK  E N H+++K  E  + +F+  G    K+PLVVG+R N+PFLL   G G +++GE++++ D   L   D  ED P YY+R  +  L E +E
Sbjct:    2 AARVFVYGTLKRGEPNHHWLTK-KENGQARFLGRGKTETKFPLVVGTRYNIPFLLARPGEGNHIEGEVYEV-DETMLSKLDILEDYPDYYDREQQTILMEQNE 102
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Fly
Match: CG2811 (gene:FBgn0035082 transcript:FBtr0309243)

HSP 1 Score: 74.3294 bits (181), Expect = 1.102e-15
Identity = 41/103 (39.81%), Postives = 62/103 (60.19%), Query Frame = 2 
Query:   83 TSFLFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYER--KLCLAESDE 385
             + +F YGTLK  E N H+++K  E  + +F+  G    K+PLVVG+R N+PFLL   G G +++GE++++ D   L   D  ED P YY+R  +  L E +E
Sbjct:    8 AARVFVYGTLKRGEPNHHWLTK-KENGQARFLGRGKTETKFPLVVGTRYNIPFLLARPGEGNHIEGEVYEV-DETMLSKLDILEDYPDYYDREQQTILMEQNE 108
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Fly
Match: Tina-1 (gene:FBgn0035083 transcript:FBtr0072411)

HSP 1 Score: 56.225 bits (134), Expect = 2.846e-9
Identity = 33/93 (35.48%), Postives = 51/93 (54.84%), Query Frame = 2 
Query:   86 SFLFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKL 364
            S LF YG LK  + +   ++        KF       +K PLV+ +R N+PFLL+  G+G  V GEI++++D + L   D+ EDC   Y R++
Sbjct:   12 SKLFVYGALKYGQPSNSILASSGN-GFAKFWCKATTTQKLPLVIATRYNIPFLLNKPGVGYYVTGEIYEVDD-RMLNSLDNLEDCEEIYTREM 102
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Zebrafish
Match: ggact.2 (gamma-glutamylamine cyclotransferase, tandem duplicate 2 [Source:NCBI gene;Acc:447805])

HSP 1 Score: 76.2554 bits (186), Expect = 6.211e-16
Identity = 40/97 (41.24%), Postives = 55/97 (56.70%), Query Frame = 2 
Query:   89 FLFFYGTLKSTELN-FHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLCLAE 376
             +F YGTLK  + N F  I       + +F+      E YPLV+   CN+PFLL++ G G+ V GEI+ + D K L F D FE+CP +Y+R L   E
Sbjct:    3 LVFVYGTLKKGQPNYFRLIDS--SNGQAEFITCARTVEPYPLVITGECNIPFLLNVPGSGQRVYGEIYSV-DQKMLEFLDWFEECPDWYQRTLIQLE 96
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Zebrafish
Match: ggact.3 (gamma-glutamylamine cyclotransferase, tandem duplicate 3 [Source:NCBI gene;Acc:100038780])

HSP 1 Score: 75.0998 bits (183), Expect = 7.107e-16
Identity = 39/96 (40.62%), Postives = 56/96 (58.33%), Query Frame = 2 
Query:   77 FQTSFLFFYGTLKSTELNFHFISKFLEIN--ELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYER 358
              T  +F YG+LK  + N H   + L  N  + +F+      E YPLV+ ++ N+PFLL++ G GK V GEI+ + D K L F D FE CP +Y+R
Sbjct:    1 MSTHHVFVYGSLKKGQPNHH---ELLNSNNGQAEFITCAQTKEPYPLVIATKHNIPFLLNVPGSGKQVSGEIYSV-DQKMLEFLDWFEKCPDWYQR 92
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Zebrafish
Match: ggact.3 (gamma-glutamylamine cyclotransferase, tandem duplicate 3 [Source:NCBI gene;Acc:100038780])

HSP 1 Score: 75.0998 bits (183), Expect = 7.107e-16
Identity = 39/96 (40.62%), Postives = 56/96 (58.33%), Query Frame = 2 
Query:   77 FQTSFLFFYGTLKSTELNFHFISKFLEIN--ELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYER 358
              T  +F YG+LK  + N H   + L  N  + +F+      E YPLV+ ++ N+PFLL++ G GK V GEI+ + D K L F D FE CP +Y+R
Sbjct:    1 MSTHHVFVYGSLKKGQPNHH---ELLNSNNGQAEFITCAQTKEPYPLVIATKHNIPFLLNVPGSGKQVSGEIYSV-DQKMLEFLDWFEKCPDWYQR 92
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Zebrafish
Match: ggact.3 (gamma-glutamylamine cyclotransferase, tandem duplicate 3 [Source:NCBI gene;Acc:100038780])

HSP 1 Score: 75.0998 bits (183), Expect = 7.107e-16
Identity = 39/96 (40.62%), Postives = 56/96 (58.33%), Query Frame = 2 
Query:   77 FQTSFLFFYGTLKSTELNFHFISKFLEIN--ELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYER 358
              T  +F YG+LK  + N H   + L  N  + +F+      E YPLV+ ++ N+PFLL++ G GK V GEI+ + D K L F D FE CP +Y+R
Sbjct:    1 MSTHHVFVYGSLKKGQPNHH---ELLNSNNGQAEFITCAQTKEPYPLVIATKHNIPFLLNVPGSGKQVSGEIYSV-DQKMLEFLDWFEKCPDWYQR 92
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Zebrafish
Match: ggact.1 (gamma-glutamylamine cyclotransferase, tandem duplicate 1 [Source:NCBI gene;Acc:777609])

HSP 1 Score: 67.3958 bits (163), Expect = 3.577e-13
Identity = 32/89 (35.96%), Postives = 53/89 (59.55%), Query Frame = 2 
Query:   92 LFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYER 358
            +F YGTLK  + N+H ++      + +F+      + YP+V+ ++   PFLL++ G G+ V GEI+ + D   L F D+FE+CP  Y+R
Sbjct:   23 VFVYGTLKKGQSNYHELTNTTH-GQAEFITCARTKDPYPMVIATKDKFPFLLNVPGSGQQVYGEIYNV-DQNMLDFLDEFEECPDLYQR 109
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Xenopus
Match: GGACT (gamma-glutamylamine cyclotransferase [Source:NCBI gene;Acc:100379707])

HSP 1 Score: 77.0258 bits (188), Expect = 1.813e-16
Identity = 38/89 (42.70%), Postives = 54/89 (60.67%), Query Frame = 2 
Query:   92 LFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYER 358
            +F YGTLK  + N H +    +  +  F   G   EKYPLV+    N+PFLL+I G G+ + GEI+ ++D+  L F DDFE CP +Y+R
Sbjct:    7 IFVYGTLKRGQPN-HTVMTCYKHGKAVFKGMGKTVEKYPLVIAEEANIPFLLNIPGTGRRIIGEIYSVDDS-MLQFLDDFEGCPNWYQR 93
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Mouse
Match: Ggact (gamma-glutamylamine cyclotransferase [Source:MGI Symbol;Acc:MGI:2385008])

HSP 1 Score: 69.707 bits (169), Expect = 2.576e-14
Identity = 41/116 (35.34%), Postives = 59/116 (50.86%), Query Frame = 2 
Query:   86 SFLFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYER-----KLCLAESDENPKTEYLCYTY 418
            + +F YGTLK  + N H +          F   G   E +PLV+    N+P+LL + G G  V GEI+++ D + L F DDFEDCP  Y+R     ++   E D +P     C+ Y
Sbjct:    2 AHIFVYGTLKRGQPN-HKVMLDHSHGLAAFRGRGCTVESFPLVIAGEHNIPWLLYLPGKGHCVTGEIYEV-DEQMLRFLDDFEDCPSMYQRTALQVQVLEWEGDGDPGDSVQCFVY 115
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Mouse
Match: Ggact (gamma-glutamylamine cyclotransferase [Source:MGI Symbol;Acc:MGI:2385008])

HSP 1 Score: 68.9366 bits (167), Expect = 1.018e-13
Identity = 41/116 (35.34%), Postives = 59/116 (50.86%), Query Frame = 2 
Query:   86 SFLFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYER-----KLCLAESDENPKTEYLCYTY 418
            + +F YGTLK  + N H +          F   G   E +PLV+    N+P+LL + G G  V GEI+++ D + L F DDFEDCP  Y+R     ++   E D +P     C+ Y
Sbjct:    2 AHIFVYGTLKRGQPN-HKVMLDHSHGLAAFRGRGCTVESFPLVIAGEHNIPWLLYLPGKGHCVTGEIYEV-DEQMLRFLDDFEDCPSMYQRTALQVQVLEWEGDGDPGDSVQCFVY 115
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Mouse
Match: Ggact (gamma-glutamylamine cyclotransferase [Source:MGI Symbol;Acc:MGI:2385008])

HSP 1 Score: 64.3142 bits (155), Expect = 1.367e-12
Identity = 36/89 (40.45%), Postives = 49/89 (55.06%), Query Frame = 2 
Query:   92 LFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYER 358
            +F YGTLK  + N H +          F   G   E +PLV+    N+P+LL + G G  V GEI+++ D + L F DDFEDCP  Y+R
Sbjct:    4 IFVYGTLKRGQPN-HKVMLDHSHGLAAFRGRGCTVESFPLVIAGEHNIPWLLYLPGKGHCVTGEIYEV-DEQMLRFLDDFEDCPSMYQR 90
[Close]
BLAST of GGACT domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9BVM4|GGACT_HUMAN (Gamma-glutamylaminecyclotransferase OS=Homo sapiens OX=9606 GN=GGACT PE=1 SV=2)

HSP 1 Score: 76.6406 bits (187), Expect = 1.486e-15
Identity = 51/145 (35.17%), Postives = 73/145 (50.34%), Query Frame = 2 
Query:   86 SFLFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLCLAE--------SDENP-KTEYLCYTYXXXXXXXXXXXXXXXDDYSSK-VHG 490
            + +F YGTLK  + N H + +        F A G   E YPLV+    N+P+LL + G G+ V+GE++ + D + L F DDFE CP  Y+R +   +        ++E P  T   C+ Y    F PE   LP  D Y S+  HG
Sbjct:    2 ALVFVYGTLKRGQPN-HRVLRDGAHGSAAFRARGRTLEPYPLVIAGEHNIPWLLHLPGSGRLVEGEVYAV-DERMLRFLDDFESCPALYQRTVLRVQLLEDRAPGAEEPPAPTAVQCFVYSRATFPPEWAQLPHHDSYDSEGPHG 144
[Close]
BLAST of GGACT domain-containing protein vs. UniProt/SwissProt
Match: sp|Q66I06|GGACB_DANRE (Gamma-glutamylaminecyclotransferase B OS=Danio rerio OX=7955 GN=ggact.2 PE=2 SV=1)

HSP 1 Score: 76.2554 bits (186), Expect = 4.689e-15
Identity = 40/97 (41.24%), Postives = 55/97 (56.70%), Query Frame = 2 
Query:   89 FLFFYGTLKSTELN-FHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLCLAE 376
             +F YGTLK  + N F  I       + +F+      E YPLV+   CN+PFLL++ G G+ V GEI+ + D K L F D FE+CP +Y+R L   E
Sbjct:    3 LVFVYGTLKKGQPNYFRLIDS--SNGQAEFITCARTVEPYPLVITGECNIPFLLNVPGSGQRVYGEIYSV-DQKMLEFLDWFEECPDWYQRTLIQLE 96
[Close]
BLAST of GGACT domain-containing protein vs. UniProt/SwissProt
Match: sp|A3KNL6|GGACC_DANRE (Gamma-glutamylaminecyclotransferase C OS=Danio rerio OX=7955 GN=ggact.3 PE=2 SV=1)

HSP 1 Score: 75.0998 bits (183), Expect = 5.365e-15
Identity = 39/96 (40.62%), Postives = 56/96 (58.33%), Query Frame = 2 
Query:   77 FQTSFLFFYGTLKSTELNFHFISKFLEIN--ELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYER 358
              T  +F YG+LK  + N H   + L  N  + +F+      E YPLV+ ++ N+PFLL++ G GK V GEI+ + D K L F D FE CP +Y+R
Sbjct:    1 MSTHHVFVYGSLKKGQPNHH---ELLNSNNGQAEFITCAQTKEPYPLVIATKHNIPFLLNVPGSGKQVSGEIYSV-DQKMLEFLDWFEKCPDWYQR 92
[Close]
BLAST of GGACT domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9W0Y2|YS11_DROME (Putative gamma-glutamylcyclotransferase CG2811 OS=Drosophila melanogaster OX=7227 GN=CG2811 PE=2 SV=2)

HSP 1 Score: 74.7146 bits (182), Expect = 6.922e-15
Identity = 41/103 (39.81%), Postives = 62/103 (60.19%), Query Frame = 2 
Query:   83 TSFLFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYER--KLCLAESDE 385
             + +F YGTLK  E N H+++K  E  + +F+  G    K+PLVVG+R N+PFLL   G G +++GE++++ D   L   D  ED P YY+R  +  L E +E
Sbjct:    8 AARVFVYGTLKRGEPNHHWLTK-KENGQARFLGRGKTETKFPLVVGTRYNIPFLLARPGEGNHIEGEVYEV-DETMLSKLDILEDYPDYYDREQQTILMEQNE 108
[Close]
BLAST of GGACT domain-containing protein vs. UniProt/SwissProt
Match: sp|Q923B0|GGACT_MOUSE (Gamma-glutamylaminecyclotransferase OS=Mus musculus OX=10090 GN=Ggact PE=1 SV=1)

HSP 1 Score: 68.9366 bits (167), Expect = 7.124e-13
Identity = 41/116 (35.34%), Postives = 59/116 (50.86%), Query Frame = 2 
Query:   86 SFLFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYER-----KLCLAESDENPKTEYLCYTY 418
            + +F YGTLK  + N H +          F   G   E +PLV+    N+P+LL + G G  V GEI+++ D + L F DDFEDCP  Y+R     ++   E D +P     C+ Y
Sbjct:    2 AHIFVYGTLKRGQPN-HKVMLDHSHGLAAFRGRGCTVESFPLVIAGEHNIPWLLYLPGKGHCVTGEIYEV-DEQMLRFLDDFEDCPSMYQRTALQVQVLEWEGDGDPGDSVQCFVY 115
[Close]
BLAST of GGACT domain-containing protein vs. TrEMBL
Match: B4LL23 (Uncharacterized protein, isoform A OS=Drosophila virilis OX=7244 GN=Dvir\GJ22268 PE=4 SV=2)

HSP 1 Score: 88.5817 bits (218), Expect = 1.947e-17
Identity = 46/109 (42.20%), Postives = 69/109 (63.30%), Query Frame = 2 
Query:   92 LFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLCLAESDENPKTEYLCYTY 418
            +F YGTLKS E N H+++        +F+A G    ++PLV+G+R N+PFLLD +G+G NV+GEI++++D   L   D  ED P YY+R+     +D+N K E  C+ Y
Sbjct:   11 VFVYGTLKSGEPNHHWLTTKTN-GHARFLAKGTTMIRFPLVIGTRYNIPFLLDKQGVGHNVQGEIYEVDDT-MLSNLDVLEDYPRYYDREPQTILTDQNEKLE--CWLY 115
[Close]
BLAST of GGACT domain-containing protein vs. TrEMBL
Match: A0A0Q9W5D7 (Uncharacterized protein, isoform B OS=Drosophila virilis OX=7244 GN=Dvir\GJ22268 PE=4 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 2.387e-17
Identity = 46/109 (42.20%), Postives = 69/109 (63.30%), Query Frame = 2 
Query:   92 LFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLCLAESDENPKTEYLCYTY 418
            +F YGTLKS E N H+++        +F+A G    ++PLV+G+R N+PFLLD +G+G NV+GEI++++D   L   D  ED P YY+R+     +D+N K E  C+ Y
Sbjct:   11 VFVYGTLKSGEPNHHWLTTKTN-GHARFLAKGTTMIRFPLVIGTRYNIPFLLDKQGVGHNVQGEIYEVDDT-MLSNLDVLEDYPRYYDREPQTILTDQNEKLE--CWLY 115
[Close]
BLAST of GGACT domain-containing protein vs. TrEMBL
Match: C1BIV8 (UPF0131 protein CG2811 OS=Osmerus mordax OX=8014 GN=YS11 PE=2 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 3.973e-17
Identity = 46/107 (42.99%), Postives = 62/107 (57.94%), Query Frame = 2 
Query:   68 MSHFQTSFLFFYGTLKSTELN-FHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLCLAESDE 385
            +S  Q + +F YGTLK  + N F  + K       +FVAN H  E+YPLV+    N+PFLL+I G G+ VKGE++ + D + L F D FE CP  Y+R     E DE
Sbjct:   17 LSSVQMTPIFVYGTLKKGQPNYFRMLDK--SNGAAEFVANAHTLERYPLVIAGEHNIPFLLNIPGEGQRVKGEVYNV-DPQMLEFLDRFEGCPTMYQRTPVKLEVDE 120
[Close]
BLAST of GGACT domain-containing protein vs. TrEMBL
Match: A0A1B6LGZ0 (GGACT domain-containing protein OS=Graphocephala atropunctata OX=36148 GN=g.2071 PE=4 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 4.185e-17
Identity = 45/109 (41.28%), Postives = 65/109 (59.63%), Query Frame = 2 
Query:   92 LFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLCLAESDENPKTEYLCYTY 418
            +F YGTLK+ E N H++++  E    +FV  G    KYPLV+ SR N+PFLLD+   G NV GE++++ D K L   D  ED P YY R+L      ++  ++  C+TY
Sbjct:   13 VFVYGTLKTGEPNHHWLTQ-PENGHSRFVGEGMTLVKYPLVIASRYNIPFLLDVPDKGHNVSGEVYEI-DEKMLASLDVLEDYPTYYTRRLETIVLKDSRSSQEQCWTY 119
[Close]
BLAST of GGACT domain-containing protein vs. TrEMBL
Match: A0A0L0CB68 (Putative gamma-glutamylcyclotransferase OS=Lucilia cuprina OX=7375 GN=FF38_11562 PE=4 SV=1)

HSP 1 Score: 86.6557 bits (213), Expect = 9.810e-17
Identity = 45/112 (40.18%), Postives = 69/112 (61.61%), Query Frame = 2 
Query:   92 LFFYGTLKSTELNFHFISKFLEINE---LKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLCLAESDENPKTEYLCYTY 418
            +F YGTLK  E N H++++    NE    +FV  G   E+ PLV+G+R N+PFLLD +G+G N+KGEI+++ D K     D  ED P+YY+R++     + N + +  C+ Y
Sbjct:   11 VFVYGTLKRGEPNHHWLTR----NENGFARFVGEGTTVERLPLVIGTRYNIPFLLDKRGLGHNIKGEIYEV-DEKMFANLDILEDYPVYYDREIQTITLNNNEQVQ--CWLY 115
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Cavefish
Match: ggact.3 (gamma-glutamylamine cyclotransferase [Source:NCBI gene;Acc:103030343])

HSP 1 Score: 75.8702 bits (185), Expect = 6.607e-16
Identity = 41/108 (37.96%), Postives = 63/108 (58.33%), Query Frame = 2 
Query:   71 SHFQTSFLFFYGTLKSTELNFHFISKFLEINELK--FVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLCLAESDEN 388
            S  Q + +F YGTLK  + N     + L+++  K  F+ +    EKYPL++  + N+PFLL+I G G++V GEI+ + D K L F D FE CP  Y+R   L + ++ 
Sbjct:   40 SVVQMTHVFVYGTLKKGQPNH---DRMLDVSNGKSEFLCSASTVEKYPLIIAGKYNVPFLLNIPGTGQHVHGEIYSV-DEKMLKFLDWFESCPHMYQRTRVLLKVEQQ 143
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Nematostella
Match: EDO33078 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STA6])

HSP 1 Score: 66.2402 bits (160), Expect = 3.000e-13
Identity = 37/109 (33.94%), Postives = 56/109 (51.38%), Query Frame = 2 
Query:   92 LFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLCLAESDENPKTEYLCYTY 418
            +F YGTLK    N H +S  L     K + +      YPLVV S   +PF++DI G G+ VKGE++++   + L   D  ED P +Y R+ C   ++++      C  Y
Sbjct:    7 IFVYGTLKQGFPNHHLLSNPLS-GTTKLLCSARTENCYPLVVASDAAIPFMMDIPGKGQRVKGEVYEVC-PQALVHLDKLEDHPRWYRRQPCQVVTEDSEPELMSCEAY 113
[Close]
BLAST of GGACT domain-containing protein vs. Ensembl Medaka
Match: ggact.3 (gamma-glutamylamine cyclotransferase [Source:NCBI gene;Acc:101169771])

HSP 1 Score: 69.3218 bits (168), Expect = 9.609e-14
Identity = 35/99 (35.35%), Postives = 58/99 (58.59%), Query Frame = 2 
Query:   92 LFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLCLAESDEN 388
            +F YGTLK  + N H+        + +F+A     ++YPLV+ +  N+PFLL++ G G+ V+GEI+++ D + L F D FE  P  Y+R +   E ++ 
Sbjct:   34 VFVYGTLKRGQPN-HYRMLDATNGKAEFLATALTTQRYPLVIATEYNIPFLLNLPGQGQRVRGEIYEV-DERMLAFLDAFESVPSMYQRTVVDLEVEDG 130
[Close]
BLAST of GGACT domain-containing protein vs. Planmine SMEST
Match: SMESG000050178.1 (SMESG000050178.1)

HSP 1 Score: 134.806 bits (338), Expect = 3.101e-38
Identity = 79/159 (49.69%), Postives = 104/159 (65.41%), Query Frame = 2 
Query:   80 QTSFLFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLCLAESDENPKTEYLCYTYXXXXXXXXXXXXXXXDDYSSKVHGKTCQITKNGMHNCLDYMVDVKI 556
             +S++F YGTLK+ E N    +K +  N++KF+  G + EK PLVV SRCN P++LD+ GIGKNVKG++F+L D   LP FD+FED P YYERKLC      N    +LC+TY L +FL +LLNLP LD YS   H K C   +N  + C+  + DVKI
Sbjct:    7 SSSYIFLYGTLKTVERNGFMTNKMISKNQIKFIGEGMMVEKRPLVVASRCNFPYILDVTGIGKNVKGQVFQLLDRYCLPEFDEFEDHPFYYERKLCRISLYNNKSKIFLCWTYLLPDFLEDLLNLPLLDRYSGIDHAKVC--PENSENCCIKSISDVKI 163
[Close]
BLAST of GGACT domain-containing protein vs. Planmine SMEST
Match: SMESG000022735.1 (SMESG000022735.1)

HSP 1 Score: 83.1889 bits (204), Expect = 7.245e-19
Identity = 47/114 (41.23%), Postives = 64/114 (56.14%), Query Frame = 2 
Query:   80 QTSFLFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLCLAESDENPKTEYL-CYTY 418
            + +F+F YGTLKS E N H +   +   +  +V  G L EK PL++ S  NLP+LLD  G G +VKGEI+K +    L   D  E  P +YERK+C     EN   + L C+ Y
Sbjct:    4 KCNFIFVYGTLKSNEPNCHLMENLIICKKFSYVGKGVLKEKRPLIIASDYNLPYLLDTTGFGNHVKGEIYKYHTNDALVDLDRLEIHPEHYERKVCKVIVLENDSFQELNCWVY 117
[Close]
BLAST of GGACT domain-containing protein vs. Planmine SMEST
Match: SMESG000022739.1 (SMESG000022739.1)

HSP 1 Score: 80.8777 bits (198), Expect = 1.529e-18
Identity = 36/94 (38.30%), Postives = 57/94 (60.64%), Query Frame = 2 
Query:   86 SFLFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLC 367
            +++F YGTLKS + N + I+  +     +++ +G + E  P+VV +  N+P+LLD+ G G  VKGEI+  +  + L   D+ E  P YYERK C
Sbjct:    3 NYIFVYGTLKSNQPNHYLIANLINKGLFQYLGDGIMKESRPMVVATEFNIPYLLDVTGAGYKVKGEIYSFDSQESLATLDELESHPTYYERKPC 96
[Close]
BLAST of GGACT domain-containing protein vs. Planmine SMEST
Match: SMESG000022739.1 (SMESG000022739.1)

HSP 1 Score: 80.8777 bits (198), Expect = 4.917e-18
Identity = 36/94 (38.30%), Postives = 57/94 (60.64%), Query Frame = 2 
Query:   86 SFLFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLC 367
            +++F YGTLKS + N + I+  +     +++ +G + E  P+VV +  N+P+LLD+ G G  VKGEI+  +  + L   D+ E  P YYERK C
Sbjct:    3 NYIFVYGTLKSNQPNHYLIANLINKGLFQYLGDGIMKESRPMVVATEFNIPYLLDVTGAGYKVKGEIYSFDSQESLATLDELESHPTYYERKPC 96
[Close]
BLAST of GGACT domain-containing protein vs. Planmine SMEST
Match: SMESG000081395.1 (SMESG000081395.1)

HSP 1 Score: 63.5438 bits (153), Expect = 4.063e-12
Identity = 35/90 (38.89%), Postives = 48/90 (53.33%), Query Frame = 2 
Query:  149 FLEINELKFVANGHLFEKYPLVVGSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLCLAESDENPKTEYLCYTY 418
             L I EL ++  G L +  PL++ S+ N PFLLD    G +VKGEI+ +N+   L   D  E  P   ERKLC   S    +  + C+TY
Sbjct:   10 LLPIEELTYIGEGILSKIRPLIIASKYNYPFLLDTTSRGLHVKGEIYIINNDSVLSKLDKLEHHPELNERKLCSVLSALGNQKIFECWTY 99
The following BLAST results are available for this feature:
BLAST of GGACT domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
GGACT3.094e-1635.17gamma-glutamylamine cyclotransferase [Source:HGNC ... [more]
GGACT3.094e-1635.17gamma-glutamylamine cyclotransferase [Source:HGNC ... [more]
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BLAST of GGACT domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
F42A10.94.230e-1642.22pep chromosome:WBcel235:III:6164645:6171165:1 gene... [more]
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BLAST of GGACT domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
CG28116.905e-1639.81gene:FBgn0035082 transcript:FBtr0072412[more]
CG28119.044e-1639.81gene:FBgn0035082 transcript:FBtr0345515[more]
CG28111.102e-1539.81gene:FBgn0035082 transcript:FBtr0309243[more]
Tina-12.846e-935.48gene:FBgn0035083 transcript:FBtr0072411[more]
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BLAST of GGACT domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ggact.26.211e-1641.24gamma-glutamylamine cyclotransferase, tandem dupli... [more]
ggact.37.107e-1640.63gamma-glutamylamine cyclotransferase, tandem dupli... [more]
ggact.37.107e-1640.63gamma-glutamylamine cyclotransferase, tandem dupli... [more]
ggact.37.107e-1640.63gamma-glutamylamine cyclotransferase, tandem dupli... [more]
ggact.13.577e-1335.96gamma-glutamylamine cyclotransferase, tandem dupli... [more]
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BLAST of GGACT domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
GGACT1.813e-1642.70gamma-glutamylamine cyclotransferase [Source:NCBI ... [more]
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BLAST of GGACT domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Ggact2.576e-1435.34gamma-glutamylamine cyclotransferase [Source:MGI S... [more]
Ggact1.018e-1335.34gamma-glutamylamine cyclotransferase [Source:MGI S... [more]
Ggact1.367e-1240.45gamma-glutamylamine cyclotransferase [Source:MGI S... [more]
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BLAST of GGACT domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9BVM4|GGACT_HUMAN1.486e-1535.17Gamma-glutamylaminecyclotransferase OS=Homo sapien... [more]
sp|Q66I06|GGACB_DANRE4.689e-1541.24Gamma-glutamylaminecyclotransferase B OS=Danio rer... [more]
sp|A3KNL6|GGACC_DANRE5.365e-1540.63Gamma-glutamylaminecyclotransferase C OS=Danio rer... [more]
sp|Q9W0Y2|YS11_DROME6.922e-1539.81Putative gamma-glutamylcyclotransferase CG2811 OS=... [more]
sp|Q923B0|GGACT_MOUSE7.124e-1335.34Gamma-glutamylaminecyclotransferase OS=Mus musculu... [more]
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BLAST of GGACT domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
B4LL231.947e-1742.20Uncharacterized protein, isoform A OS=Drosophila v... [more]
A0A0Q9W5D72.387e-1742.20Uncharacterized protein, isoform B OS=Drosophila v... [more]
C1BIV83.973e-1742.99UPF0131 protein CG2811 OS=Osmerus mordax OX=8014 G... [more]
A0A1B6LGZ04.185e-1741.28GGACT domain-containing protein OS=Graphocephala a... [more]
A0A0L0CB689.810e-1740.18Putative gamma-glutamylcyclotransferase OS=Lucilia... [more]
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BLAST of GGACT domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ggact.36.607e-1637.96gamma-glutamylamine cyclotransferase [Source:NCBI ... [more]
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BLAST of GGACT domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of GGACT domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of GGACT domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO330783.000e-1333.94Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of GGACT domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ggact.39.609e-1435.35gamma-glutamylamine cyclotransferase [Source:NCBI ... [more]
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BLAST of GGACT domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000050178.13.101e-3849.69SMESG000050178.1[more]
SMESG000022735.17.245e-1941.23SMESG000022735.1[more]
SMESG000022739.11.529e-1838.30SMESG000022739.1[more]
SMESG000022739.14.917e-1838.30SMESG000022739.1[more]
SMESG000081395.14.063e-1238.89SMESG000081395.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011479 ID=SMED30011479|Name=GGACT domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1052bp
GAGTAACAATAACAAAGAATAACCATTGTTTATATGTATTGTCAACAAGC
ACTTCAAAGTTCAACCAATGAGCCATTTTCAAACGTCATTTTTATTTTTT
TATGGAACTTTAAAGTCAACAGAATTAAATTTTCATTTTATCTCAAAATT
TTTGGAAATAAATGAGCTCAAGTTTGTAGCAAATGGTCATTTGTTTGAAA
AATATCCCTTAGTTGTTGGATCTAGGTGTAATTTGCCTTTTTTGTTAGAT
ATAAAAGGAATTGGAAAAAACGTTAAAGGAGAAATATTTAAATTGAACGA
TGCAAAATTTTTACCTTTCTTCGATGATTTTGAAGATTGTCCCATTTATT
ATGAACGTAAATTATGTTTAGCTGAATCGGACGAAAACCCAAAGACTGAA
TATTTATGTTATACTTATTTTCTAACAAATTTTTTACCCGAACTTCTGAA
TCTCCCATTTCTTGATGATTATTCCAGCAAAGTTCACGGAAAAACATGTC
AAATAACAAAAAATGGAATGCATAATTGTCTTGATTACATGGTTGATGTG
AAAATTACATAAATTTATTATTTTTTTATTAATTACGTTTTCATATTTTA
ATCAATTTATCATTTAATTAAAACCAAATTTCATTAATAAAAAAATTTCA
GTAGAAAACTCCTGATTTATAAATTATAAATAATGATTTTACTGAAAATT
AAAATTTATAAAATTTCACAGCACATTAATCAATCAATAAAGCAATATTA
TCGTGAGAGCATATATAAACAAATTAATTTAATATTAATTTTGTGTGGAA
ATTGTGCAAAAATTTCTCTAAATATAAATTATTGAAAAACATTTTGAAAA
AATTCTTAAAATTGAAAAGTGCATCCGTGAAATCAGTAGCATTAGAGGAA
GTACAAACATCCGAAATATCAATCAAATCGTCAATTCAAACAATCGTAGA
AAATTCATTCATTAATCAGTTTATTTTTATCGATTTATTTGTTTGTTTGT
ATATGTTATTTATTATTTTAGTTTGTTATTTATTACTTTAATTGTAAGGA
TA
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protein sequence of SMED30011479-orf-1

>SMED30011479-orf-1 ID=SMED30011479-orf-1|Name=SMED30011479-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=165bp
MSHFQTSFLFFYGTLKSTELNFHFISKFLEINELKFVANGHLFEKYPLVV
GSRCNLPFLLDIKGIGKNVKGEIFKLNDAKFLPFFDDFEDCPIYYERKLC
LAESDENPKTEYLCYTYFLTNFLPELLNLPFLDDYSSKVHGKTCQITKNG
MHNCLDYMVDVKIT*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: INTERPRO
TermDefinition
IPR009288AIG2-like
IPR013024GGCT-like
Vocabulary: molecular function
TermDefinition
GO:0016740transferase activity