NEDD8

Overview


Name	NEDD8
Smed ID	SMED30011383
Length (bp)	1028

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of NEDD8 (SMED30011383) t-SNE clustered cells

Violin plots show distribution of expression levels for NEDD8 (SMED30011383) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of NEDD8 (SMED30011383) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for NEDD8 (SMED30011383) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30011383

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Expressed In	Reference Transcript	Published Transcript	Transcriptome	Publication
pharynx	SMED30011383	dd_Smed_v4_403_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
protonephridia	SMED30011383	dd_Smed_v4_403_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30011383	dd_Smed_v4_403_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30011383	dd_Smed_v4_403_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30011383	dd_Smed_v4_403_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30011383	dd_Smed_v4_403_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30011383	dd_Smed_v4_403_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30011383	dd_Smed_v4_403_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30011383	dd_Smed_v6_403_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of NEDD8 vs. Ensembl Human
Match: NEDD8 (NEDD8 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:7732])

HSP 1 Score: 120.553 bits (301), Expect = 1.227e-33
Identity = 69/78 (88.46%), Postives = 74/78 (94.87%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGNA 293
            MLIKVKTLTGKEIEIDIEPTDKVERIKER+EEKEGIPPQQQRLI+SGKQMND+K  A+YKI+GGSVLHLVLALRGG  
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKILGGSVLHLVLALRGGGG 78

[Close]

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGNA 293
            MLIKVKTLTGKEIEIDIEPTDKVERIKER+EEKEGIPPQQQRLI+SGKQMND+K  A+YKI+GGSVLHLVLALRGG  
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKILGGSVLHLVLALRGGGG 78

[Close]

BLAST of NEDD8 vs. Ensembl Human
Match: NEDD8-MDP1 (NEDD8-MDP1 readthrough [Source:HGNC Symbol;Acc:HGNC:39551])

HSP 1 Score: 93.5893 bits (231), Expect = 2.454e-23
Identity = 55/62 (88.71%), Postives = 60/62 (96.77%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKII 245
            MLIKVKTLTGKEIEIDIEPTDKVERIKER+EEKEGIPPQQQRLI+SGKQMND+K  A+YKI+
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKIL 62

[Close]

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKII 245
            MLIKVKTLTGKEIEIDIEPTDKVERIKER+EEKEGIPPQQQRLI+SGKQMND+K  A+YKI+
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKIL 62

[Close]

BLAST of NEDD8 vs. Ensembl Human
Match: UBB (ubiquitin B [Source:HGNC Symbol;Acc:HGNC:12463])

HSP 1 Score: 80.4925 bits (197), Expect = 2.354e-18
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Celegans
Match: ned-8 (NEDD8 [Source:UniProtKB/Swiss-Prot;Acc:Q93725])

HSP 1 Score: 114.775 bits (286), Expect = 6.451e-32
Identity = 64/76 (84.21%), Postives = 72/76 (94.74%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            MLIKVKTLTGKEIE+DIEP D+VERIKE++EEKEGIPP QQRLIF+GKQMNDDK  A+YK++GGSVLHLVLALRGG
Sbjct:    1 MLIKVKTLTGKEIELDIEPNDRVERIKEKVEEKEGIPPPQQRLIFAGKQMNDDKTAADYKVLGGSVLHLVLALRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Celegans
Match: ubq-2 (Ubiquitin-60S ribosomal protein L40 Ubiquitin 60S ribosomal protein L40 [Source:UniProtKB/Swiss-Prot;Acc:P49632])

HSP 1 Score: 77.0258 bits (188), Expect = 3.860e-17
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Celegans
Match: ubq-1 (Polyubiquitin-A Ubiquitin Ubiquitin-related [Source:UniProtKB/Swiss-Prot;Acc:P0CG71])

HSP 1 Score: 77.411 bits (189), Expect = 2.564e-15
Identity = 43/77 (55.84%), Postives = 59/77 (76.62%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGN 290
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG+
Sbjct:  761 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGD 837

HSP 2 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

HSP 3 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:   77 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 152

HSP 4 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  153 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 228

HSP 5 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  229 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 304

HSP 6 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  305 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 380

HSP 7 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  457 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 532

HSP 8 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  533 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 608

HSP 9 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  609 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 684

HSP 10 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  685 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 760

HSP 11 Score: 73.9442 bits (180), Expect = 3.728e-14
Identity = 42/76 (55.26%), Postives = 57/76 (75.00%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTL GK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  381 MQIFVKTLIGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 456

[Close]

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGN 290
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG+
Sbjct:  761 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGD 837

HSP 2 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

HSP 3 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:   77 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 152

HSP 4 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  153 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 228

HSP 5 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  229 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 304

HSP 6 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  305 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 380

HSP 7 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  457 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 532

HSP 8 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  533 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 608

HSP 9 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  609 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 684

HSP 10 Score: 76.6406 bits (187), Expect = 4.472e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  685 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 760

HSP 11 Score: 73.9442 bits (180), Expect = 3.728e-14
Identity = 42/76 (55.26%), Postives = 57/76 (75.00%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTL GK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  381 MQIFVKTLIGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 456

[Close]

BLAST of NEDD8 vs. Ensembl Celegans
Match: ubq-1 (Polyubiquitin-A Ubiquitin Ubiquitin-related [Source:UniProtKB/Swiss-Prot;Acc:P0CG71])

HSP 1 Score: 76.6406 bits (187), Expect = 3.500e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

HSP 2 Score: 76.6406 bits (187), Expect = 3.500e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:   77 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 152

HSP 3 Score: 76.6406 bits (187), Expect = 3.500e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  153 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 228

HSP 4 Score: 76.6406 bits (187), Expect = 3.500e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  229 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 304

HSP 5 Score: 76.6406 bits (187), Expect = 3.500e-15
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  305 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 380

HSP 6 Score: 73.9442 bits (180), Expect = 2.939e-14
Identity = 42/76 (55.26%), Postives = 57/76 (75.00%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTL GK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  381 MQIFVKTLIGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 456

[Close]

BLAST of NEDD8 vs. Ensembl Fly
Match: Nedd8 (gene:FBgn0032725 transcript:FBtr0342928)

HSP 1 Score: 122.865 bits (307), Expect = 1.000e-34
Identity = 69/78 (88.46%), Postives = 75/78 (96.15%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGNA 293
            MLIKVKTLTGKEIEIDIEPTDKV+RIKER+EEKEGIPPQQQRLIFSGKQMNDDK  A+YK+ GGSVLHLVLALRGG++
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVDRIKERVEEKEGIPPQQQRLIFSGKQMNDDKTAADYKVQGGSVLHLVLALRGGDS 78

[Close]

BLAST of NEDD8 vs. Ensembl Fly
Match: Nedd8 (gene:FBgn0032725 transcript:FBtr0081192)

HSP 1 Score: 122.865 bits (307), Expect = 1.000e-34
Identity = 69/78 (88.46%), Postives = 75/78 (96.15%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGNA 293
            MLIKVKTLTGKEIEIDIEPTDKV+RIKER+EEKEGIPPQQQRLIFSGKQMNDDK  A+YK+ GGSVLHLVLALRGG++
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVDRIKERVEEKEGIPPQQQRLIFSGKQMNDDKTAADYKVQGGSVLHLVLALRGGDS 78

[Close]

BLAST of NEDD8 vs. Ensembl Fly
Match: RpL40 (gene:FBgn0003941 transcript:FBtr0334787)

HSP 1 Score: 80.4925 bits (197), Expect = 2.559e-18
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Fly
Match: RpL40 (gene:FBgn0003941 transcript:FBtr0077470)

HSP 1 Score: 80.4925 bits (197), Expect = 2.559e-18
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Fly
Match: RpS27A (gene:FBgn0003942 transcript:FBtr0080016)

HSP 1 Score: 80.1073 bits (196), Expect = 7.854e-18
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Zebrafish
Match: nedd8l (NEDD8 ubiquitin like modifier, like [Source:ZFIN;Acc:ZDB-GENE-040718-295])

HSP 1 Score: 119.398 bits (298), Expect = 1.907e-33
Identity = 69/77 (89.61%), Postives = 73/77 (94.81%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGN 290
            MLIKVKTLTGKEIEIDIEPTDKVERIKER+EEKEGIPPQQQRLI+SGKQMND+K  A+YKI GGSVLHLVLALRGG 
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKIQGGSVLHLVLALRGGE 77

[Close]

BLAST of NEDD8 vs. Ensembl Zebrafish
Match: nedd8 (NEDD8 ubiquitin like modifier [Source:ZFIN;Acc:ZDB-GENE-030616-588])

HSP 1 Score: 119.398 bits (298), Expect = 3.058e-33
Identity = 69/77 (89.61%), Postives = 73/77 (94.81%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGN 290
            MLIKVKTLTGKEIEIDIEPTDKVERIKER+EEKEGIPPQQQRLI+SGKQMND+K  A+YKI GGSVLHLVLALRGG 
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKIQGGSVLHLVLALRGGQ 77

[Close]

BLAST of NEDD8 vs. Ensembl Zebrafish
Match: nedd8l (NEDD8 ubiquitin like modifier, like [Source:ZFIN;Acc:ZDB-GENE-040718-295])

HSP 1 Score: 110.538 bits (275), Expect = 9.694e-30
Identity = 64/74 (86.49%), Postives = 69/74 (93.24%), Query Frame = 3

Query:   66 IKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            I  +TLTGKEIEIDIEPTDKVERIKER+EEKEGIPPQQQRLI+SGKQMND+K  A+YKI GGSVLHLVLALRGG
Sbjct:   19 ITSQTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKIQGGSVLHLVLALRGG 92

[Close]

BLAST of NEDD8 vs. Ensembl Zebrafish
Match: ubb (ubiquitin B [Source:ZFIN;Acc:ZDB-GENE-050411-10])

HSP 1 Score: 79.7221 bits (195), Expect = 2.111e-18
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Zebrafish
Match: uba52 (ubiquitin A-52 residue ribosomal protein fusion product 1 [Source:ZFIN;Acc:ZDB-GENE-051023-7])

HSP 1 Score: 80.4925 bits (197), Expect = 3.575e-18
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Xenopus
Match: nedd8 (neural precursor cell expressed, developmentally down-regulated 8 [Source:NCBI gene;Acc:549727])

HSP 1 Score: 119.398 bits (298), Expect = 2.895e-33
Identity = 69/76 (90.79%), Postives = 73/76 (96.05%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            MLIKVKTLTGKEIEIDIEPTDKVERIKER+EEKEGIPPQQQRLI+SGKQMND+K  A+YKI GGSVLHLVLALRGG
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKIQGGSVLHLVLALRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Xenopus
Match: uba52 (ubiquitin A-52 residue ribosomal protein fusion product 1 [Source:NCBI gene;Acc:448705])

HSP 1 Score: 80.4925 bits (197), Expect = 5.252e-18
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Xenopus
Match: rps27a (ribosomal protein S27a [Source:NCBI gene;Acc:548926])

HSP 1 Score: 80.4925 bits (197), Expect = 1.066e-17
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Xenopus
Match: ENSXETT00000033679.1 (ubiquitin C [Source:NCBI gene;Acc:448120])

HSP 1 Score: 79.7221 bits (195), Expect = 7.589e-17
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

HSP 2 Score: 79.7221 bits (195), Expect = 7.589e-17
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:   77 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 152

HSP 3 Score: 79.7221 bits (195), Expect = 7.589e-17
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  153 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 228

[Close]

BLAST of NEDD8 vs. Ensembl Xenopus
Match: pdcd11 (programmed cell death 11 [Source:Xenbase;Acc:XB-GENE-967218])

HSP 1 Score: 82.4185 bits (202), Expect = 1.334e-16
Identity = 45/77 (58.44%), Postives = 61/77 (79.22%), Query Frame = 3

Query:   57 VMLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            +M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D +++A+Y I   S LHLVL LRGG
Sbjct:  424 IMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDCRSLADYNIQKESTLHLVLRLRGG 500

HSP 2 Score: 80.1073 bits (196), Expect = 6.642e-16
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

HSP 3 Score: 80.1073 bits (196), Expect = 6.642e-16
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:   77 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 152

HSP 4 Score: 80.1073 bits (196), Expect = 6.642e-16
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  153 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 228

HSP 5 Score: 80.1073 bits (196), Expect = 6.642e-16
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  229 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 304

HSP 6 Score: 80.1073 bits (196), Expect = 6.642e-16
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  305 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 380

HSP 7 Score: 79.7221 bits (195), Expect = 8.351e-16
Identity = 44/76 (57.89%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + + +Y I   S LHLVL LRGG
Sbjct:  577 MQIFVKTLTGKTITLEVEPSDTIENVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLCDYNIQKESTLHLVLRLRGG 652

HSP 8 Score: 79.337 bits (194), Expect = 1.284e-15
Identity = 44/76 (57.89%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + + +Y I   S LHLVL LRGG
Sbjct:  501 MQIFVKTLTGKTITLEVEPSDTIENVKGKIQDKEGIPPDQQRLIFAGKQLEDGRTLCDYNIQKESTLHLVLRLRGG 576

[Close]

BLAST of NEDD8 vs. Ensembl Mouse
Match: Nedd8 (neural precursor cell expressed, developmentally down-regulated gene 8 [Source:MGI Symbol;Acc:MGI:97301])

HSP 1 Score: 105.916 bits (263), Expect = 3.470e-28
Identity = 61/68 (89.71%), Postives = 66/68 (97.06%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLH 263
            MLIKVKTLTGKEIEIDIEPTDKVERIKER+EEKEGIPPQQQRLI+SGKQMND+K  A+YKI+GGSVLH
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKILGGSVLH 68

[Close]

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLH 263
            MLIKVKTLTGKEIEIDIEPTDKVERIKER+EEKEGIPPQQQRLI+SGKQMND+K  A+YKI+GGSVLH
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKILGGSVLH 68

[Close]

BLAST of NEDD8 vs. Ensembl Mouse
Match: Gm8797 (predicted pseudogene 8797 [Source:MGI Symbol;Acc:MGI:3643769])

HSP 1 Score: 79.7221 bits (195), Expect = 1.643e-18
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Mouse
Match: Uba52 (ubiquitin A-52 residue ribosomal protein fusion product 1 [Source:MGI Symbol;Acc:MGI:98887])

HSP 1 Score: 80.4925 bits (197), Expect = 1.845e-18
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Mouse
Match: Gm11808 (predicted gene 11808 [Source:MGI Symbol;Acc:MGI:3649356])

HSP 1 Score: 80.4925 bits (197), Expect = 3.977e-18
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. UniProt/SwissProt
Match: sp|Q9VJ33|NEDD8_DROME (NEDD8 OS=Drosophila melanogaster OX=7227 GN=Nedd8 PE=1 SV=1)

HSP 1 Score: 122.865 bits (307), Expect = 1.003e-33
Identity = 69/78 (88.46%), Postives = 75/78 (96.15%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGNA 293
            MLIKVKTLTGKEIEIDIEPTDKV+RIKER+EEKEGIPPQQQRLIFSGKQMNDDK  A+YK+ GGSVLHLVLALRGG++
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVDRIKERVEEKEGIPPQQQRLIFSGKQMNDDKTAADYKVQGGSVLHLVLALRGGDS 78

[Close]

BLAST of NEDD8 vs. UniProt/SwissProt
Match: sp|Q4PLJ0|NEDD8_RABIT (NEDD8 OS=Oryctolagus cuniculus OX=9986 GN=NEDD8 PE=3 SV=1)

HSP 1 Score: 120.553 bits (301), Expect = 5.891e-33
Identity = 69/78 (88.46%), Postives = 74/78 (94.87%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGNA 293
            MLIKVKTLTGKEIEIDIEPTDKVERIKER+EEKEGIPPQQQRLI+SGKQMND+K  A+YKI+GGSVLHLVLALRGG  
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKILGGSVLHLVLALRGGGG 78

[Close]

BLAST of NEDD8 vs. UniProt/SwissProt
Match: sp|Q15843|NEDD8_HUMAN (NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1)

HSP 1 Score: 120.553 bits (301), Expect = 5.891e-33
Identity = 69/78 (88.46%), Postives = 74/78 (94.87%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGNA 293
            MLIKVKTLTGKEIEIDIEPTDKVERIKER+EEKEGIPPQQQRLI+SGKQMND+K  A+YKI+GGSVLHLVLALRGG  
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKILGGSVLHLVLALRGGGG 78

[Close]

BLAST of NEDD8 vs. UniProt/SwissProt
Match: sp|P61282|NEDD8_BOVIN (NEDD8 OS=Bos taurus OX=9913 GN=NEDD8 PE=3 SV=1)

HSP 1 Score: 120.553 bits (301), Expect = 5.891e-33
Identity = 69/78 (88.46%), Postives = 74/78 (94.87%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGNA 293
            MLIKVKTLTGKEIEIDIEPTDKVERIKER+EEKEGIPPQQQRLI+SGKQMND+K  A+YKI+GGSVLHLVLALRGG  
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKILGGSVLHLVLALRGGGG 78

[Close]

BLAST of NEDD8 vs. UniProt/SwissProt
Match: sp|Q93725|NEDD8_CAEEL (NEDD8 OS=Caenorhabditis elegans OX=6239 GN=ned-8 PE=1 SV=1)

HSP 1 Score: 114.775 bits (286), Expect = 8.206e-31
Identity = 64/76 (84.21%), Postives = 72/76 (94.74%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            MLIKVKTLTGKEIE+DIEP D+VERIKE++EEKEGIPP QQRLIF+GKQMNDDK  A+YK++GGSVLHLVLALRGG
Sbjct:    1 MLIKVKTLTGKEIELDIEPNDRVERIKEKVEEKEGIPPPQQRLIFAGKQMNDDKTAADYKVLGGSVLHLVLALRGG 76

[Close]

BLAST of NEDD8 vs. TrEMBL
Match: A0A484BGE8 (Ubiquitin-like domain-containing protein OS=Drosophila navojoa OX=7232 GN=AWZ03_005793 PE=4 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 1.064e-31
Identity = 70/77 (90.91%), Postives = 74/77 (96.10%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGN 290
            MLIKVKTLTGKEIEIDIEPTDKV+RIKER+EEKEGIPPQQQRLIFSGKQMNDDK  A+YK+ GGSVLHLVLALRGGN
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVDRIKERVEEKEGIPPQQQRLIFSGKQMNDDKTAADYKVQGGSVLHLVLALRGGN 77

[Close]

BLAST of NEDD8 vs. TrEMBL
Match: A0A3B0JBK2 (Blast:NEDD8 OS=Drosophila guanche OX=7266 GN=DGUA_6G012258 PE=4 SV=1)

HSP 1 Score: 123.635 bits (309), Expect = 1.104e-31
Identity = 70/78 (89.74%), Postives = 75/78 (96.15%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGNA 293
            MLIKVKTLTGKEIEIDIEPTDKV+RIKER+EEKEGIPPQQQRLIFSGKQMNDDK  A+YK+ GGSVLHLVLALRGG+A
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVDRIKERVEEKEGIPPQQQRLIFSGKQMNDDKTAADYKVQGGSVLHLVLALRGGHA 78

[Close]

BLAST of NEDD8 vs. TrEMBL
Match: B4I5M6 (GM17051 OS=Drosophila sechellia OX=7238 GN=Dsec\GM17051 PE=4 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 2.138e-31
Identity = 69/78 (88.46%), Postives = 75/78 (96.15%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGNA 293
            MLIKVKTLTGKEIEIDIEPTDKV+RIKER+EEKEGIPPQQQRLIFSGKQMNDDK  A+YK+ GGSVLHLVLALRGG++
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVDRIKERVEEKEGIPPQQQRLIFSGKQMNDDKTAADYKVQGGSVLHLVLALRGGDS 78

[Close]

BLAST of NEDD8 vs. TrEMBL
Match: A0A1S3DU76 (NEDD8 OS=Diaphorina citri OX=121845 GN=LOC103524748 PE=4 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 2.224e-31
Identity = 70/78 (89.74%), Postives = 75/78 (96.15%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGNA 293
            MLIKVKTLTGKEIEIDIEPTDKVERIKER+EEKEGIPPQQQRLIFSGKQMND+K  AEYK+ GGSVLHLVLALRGG++
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIFSGKQMNDEKTAAEYKVQGGSVLHLVLALRGGHS 78

[Close]

BLAST of NEDD8 vs. TrEMBL
Match: Q29LT5 (Ubiquitin-like domain-containing protein OS=Drosophila pseudoobscura pseudoobscura OX=46245 GN=Dpse\GA10488 PE=4 SV=2)

HSP 1 Score: 122.865 bits (307), Expect = 2.763e-31
Identity = 69/78 (88.46%), Postives = 75/78 (96.15%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGNA 293
            MLIKVKTLTGKEIEIDIEPTDKV+RIKER+EEKEGIPPQQQRLIFSGKQMNDDK  A+YK+ GGSVLHLVLALRGG++
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVDRIKERVEEKEGIPPQQQRLIFSGKQMNDDKTAADYKVQGGSVLHLVLALRGGHS 78

[Close]

BLAST of NEDD8 vs. Ensembl Cavefish
Match: nedd8 (NEDD8 [Source:NCBI gene;Acc:103040682])

HSP 1 Score: 119.783 bits (299), Expect = 1.478e-33
Identity = 69/78 (88.46%), Postives = 73/78 (93.59%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGNA 293
            MLIKVKTLTGKEIEIDIEPTDKVERIKER+EEKEGIPPQQQRLI+SGKQMND+K  A+YKI GGSVLHLVLALRGG  
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKIQGGSVLHLVLALRGGRG 78

[Close]

BLAST of NEDD8 vs. Ensembl Cavefish
Match: nedd8l (NEDD8-like [Source:NCBI gene;Acc:103044361])

HSP 1 Score: 118.242 bits (295), Expect = 5.888e-33
Identity = 68/77 (88.31%), Postives = 73/77 (94.81%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGN 290
            MLIKVKTLTGKEIEIDIEPTDKVERIKER+EEKEGIPPQQQRLI+SGKQMND+K  ++YKI GGSVLHLVLALRGG 
Sbjct:    1 MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTASDYKIQGGSVLHLVLALRGGR 77

[Close]

BLAST of NEDD8 vs. Ensembl Cavefish
Match: uba52 (ubiquitin A-52 residue ribosomal protein fusion product 1 [Source:NCBI gene;Acc:103027541])

HSP 1 Score: 80.4925 bits (197), Expect = 3.030e-18
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Cavefish
Match: rps27a (ribosomal protein S27a [Source:NCBI gene;Acc:103044043])

HSP 1 Score: 80.4925 bits (197), Expect = 6.733e-18
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Sea Lamprey
Match: UBB (ubiquitin B [Source:HGNC Symbol;Acc:HGNC:12463])

HSP 1 Score: 84.3445 bits (207), Expect = 2.093e-18
Identity = 45/85 (52.94%), Postives = 64/85 (75.29%), Query Frame = 3

Query:   33 VFFIYTFIVMLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            V +   +++M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    5 VRYCKHYLIMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 89

HSP 2 Score: 80.1073 bits (196), Expect = 6.037e-17
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:   90 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 165

HSP 3 Score: 80.1073 bits (196), Expect = 6.037e-17
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  166 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 241

HSP 4 Score: 80.1073 bits (196), Expect = 6.037e-17
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  242 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 317

HSP 5 Score: 80.1073 bits (196), Expect = 6.037e-17
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  318 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 393

[Close]

BLAST of NEDD8 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007011.1 (pep scaffold:Pmarinus_7.0:GL484716:14406:16135:-1 gene:ENSPMAG00000006335.1 transcript:ENSPMAT00000007011.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.1434 bits (126), Expect = 3.480e-9
Identity = 25/42 (59.52%), Postives = 31/42 (73.81%), Query Frame = 3

Query:  162 GIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            GIPP QQR IF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 GIPPDQQR-IFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 41

[Close]

BLAST of NEDD8 vs. Ensembl Sea Lamprey
Match: zfand4 (zinc finger, AN1-type domain 4 [Source:ZFIN;Acc:ZDB-GENE-090312-102])

HSP 1 Score: 53.5286 bits (127), Expect = 4.253e-8
Identity = 34/89 (38.20%), Postives = 51/89 (57.30%), Query Frame = 3

Query:   24 SILVFFIYTFI-VMLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            S  V + + F   M + ++TLTG   EI + P + V  +K +I+  EGIP  QQ LI+   ++ DD  + +Y I  G  + LVLA+RGG
Sbjct:   15 SPYVSYSFPFYETMEVLIETLTGTFFEIRVSPFESVMSVKAKIQRLEGIPITQQHLIWRNIELEDDYCLHDYHITHGCTIKLVLAMRGG 103

[Close]

BLAST of NEDD8 vs. Ensembl Yeast
Match: RUB1 (Ubiquitin-like protein with similarity to mammalian NEDD8; conjugation (neddylation) substrates include the cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2 enzyme) [Source:SGD;Acc:S000002546])

HSP 1 Score: 79.337 bits (194), Expect = 2.698e-19
Identity = 46/77 (59.74%), Postives = 59/77 (76.62%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGN 290
            M++KVKTLTGKEI ++++ +D V  IKE +EEKEGIPP QQRLIF GKQ++D   V +  ++ G  LHLVL LRGGN
Sbjct:    1 MIVKVKTLTGKEISVELKESDLVYHIKELLEEKEGIPPSQQRLIFQGKQIDDKLTVTDAHLVEGMQLHLVLTLRGGN 77

[Close]

BLAST of NEDD8 vs. Ensembl Yeast
Match: RPL40B (Ubiquitin-ribosomal 60S subunit protein L40B fusion protein; cleaved to yield ubiquitin and ribosomal protein L40B; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; homologous to mammalian ribosomal protein L40, no bacterial homolog; RPL40B has a paralog, RPL40A, that arose from the whole genome duplication [Source:SGD;Acc:S000001802])

HSP 1 Score: 77.0258 bits (188), Expect = 7.742e-18
Identity = 42/76 (55.26%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D ++ +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Yeast
Match: RPL40A (Ubiquitin-ribosomal 60S subunit protein L40A fusion protein; cleaved to yield ubiquitin and ribosomal protein L40A; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; homologous to mammalian ribosomal protein L40, no bacterial homolog; RPL40A has a paralog, RPL40B, that arose from the whole genome duplication; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000001410])

HSP 1 Score: 77.0258 bits (188), Expect = 7.742e-18
Identity = 42/76 (55.26%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D ++ +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Yeast
Match: UBI4 (Ubiquitin; becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system; essential for the cellular stress response; encoded as a polyubiquitin precursor comprised of 5 head-to-tail repeats; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003962])

HSP 1 Score: 79.337 bits (194), Expect = 4.919e-17
Identity = 43/77 (55.84%), Postives = 59/77 (76.62%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGN 290
            M I VKTLTGK I +++E +D ++ +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGGN
Sbjct:  305 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGN 381

HSP 2 Score: 76.6406 bits (187), Expect = 3.756e-16
Identity = 42/76 (55.26%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D ++ +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

HSP 3 Score: 76.6406 bits (187), Expect = 3.756e-16
Identity = 42/76 (55.26%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D ++ +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:   77 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 152

HSP 4 Score: 76.6406 bits (187), Expect = 3.756e-16
Identity = 42/76 (55.26%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D ++ +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  153 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 228

HSP 5 Score: 76.6406 bits (187), Expect = 3.756e-16
Identity = 42/76 (55.26%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D ++ +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  229 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 304

[Close]

BLAST of NEDD8 vs. Ensembl Yeast
Match: RPS31 (Fusion protein cleaved to yield ribosomal protein S31 and ubiquitin; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; interacts genetically with translation factor eIF2B; homologous to mammalian ribosomal protein S27A, no bacterial homolog [Source:SGD;Acc:S000004157])

HSP 1 Score: 67.3958 bits (163), Expect = 3.039e-14
Identity = 37/70 (52.86%), Postives = 53/70 (75.71%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLV 269
            M I VKTLTGK I +++E +D ++ +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLV
Sbjct:    1 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLV 70

[Close]

BLAST of NEDD8 vs. Ensembl Nematostella
Match: EDO45561 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSG9])

HSP 1 Score: 80.4925 bits (197), Expect = 1.567e-18
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

HSP 2 Score: 50.0618 bits (118), Expect = 1.221e-7
Identity = 31/71 (43.66%), Postives = 50/71 (70.42%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVL 272
            M I VK    K   +D+E +D VE +KE+I+ +EGIPP+ QRL++  +++ D++++A+Y I  GS+LHL L
Sbjct:   77 MQISVKA-HWKTFTLDVEASDTVESVKEKIQNREGIPPKVQRLLYEEEELVDNRSLADYNIKQGSILHLFL 146

[Close]

BLAST of NEDD8 vs. Ensembl Nematostella
Match: EDO48503 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJ25])

HSP 1 Score: 80.1073 bits (196), Expect = 2.757e-18
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Nematostella
Match: EDO32403 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SV54])

HSP 1 Score: 80.8777 bits (198), Expect = 7.035e-18
Identity = 44/77 (57.14%), Postives = 59/77 (76.62%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGN 290
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQR IF+GKQ+ D + +++Y I   S LHLVL LRGGN
Sbjct:  153 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRFIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGN 229

HSP 2 Score: 79.7221 bits (195), Expect = 1.837e-17
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

HSP 3 Score: 79.7221 bits (195), Expect = 1.837e-17
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:   77 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 152

[Close]

BLAST of NEDD8 vs. Ensembl Nematostella
Match: EDO32547 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUP6])

HSP 1 Score: 82.4185 bits (202), Expect = 2.292e-17
Identity = 45/77 (58.44%), Postives = 60/77 (77.92%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGN 290
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGGN
Sbjct:  457 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGN 533

HSP 2 Score: 79.7221 bits (195), Expect = 1.718e-16
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

HSP 3 Score: 79.7221 bits (195), Expect = 1.718e-16
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:   77 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 152

HSP 4 Score: 79.7221 bits (195), Expect = 1.718e-16
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  153 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 228

HSP 5 Score: 79.7221 bits (195), Expect = 1.718e-16
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  229 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 304

HSP 6 Score: 79.7221 bits (195), Expect = 1.718e-16
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  305 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 380

HSP 7 Score: 79.7221 bits (195), Expect = 1.718e-16
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:  381 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 456

[Close]

BLAST of NEDD8 vs. Ensembl Nematostella
Match: EDO31255 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYF9])

HSP 1 Score: 63.1586 bits (152), Expect = 5.568e-13
Identity = 35/65 (53.85%), Postives = 51/65 (78.46%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGS 254
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I  G+
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKGN 65

[Close]

BLAST of NEDD8 vs. Ensembl Medaka
Match: ENSORLT00000033696.1 (pep primary_assembly:ASM223467v1:18:18100789:18102949:1 gene:ENSORLG00000024017.1 transcript:ENSORLT00000033696.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 109.383 bits (272), Expect = 1.397e-29
Identity = 66/76 (86.84%), Postives = 71/76 (93.42%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M IK+ TLTGKEIEIDIEPTDKVERIKER+EEKEGIPPQQQRLI+SGKQMND+K  A+YKI GGSVLHLVLALRGG
Sbjct:    1 MYIKL-TLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKIQGGSVLHLVLALRGG 75

[Close]

BLAST of NEDD8 vs. Ensembl Medaka
Match: ENSORLT00000041155.1 (pep primary_assembly:ASM223467v1:17:17794475:17794948:1 gene:ENSORLG00000027923.1 transcript:ENSORLT00000041155.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 81.2629 bits (199), Expect = 5.434e-19
Identity = 36/43 (83.72%), Postives = 40/43 (93.02%), Query Frame = 3

Query:  162 GIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGN 290
            GIPPQQQRLI+SGKQMND+K  A+YKI GGSVLHLVLALRGG+
Sbjct:   38 GIPPQQQRLIYSGKQMNDEKTAADYKIQGGSVLHLVLALRGGS 80

[Close]

BLAST of NEDD8 vs. Ensembl Medaka
Match: rps27a (ribosomal protein S27a [Source:NCBI gene;Acc:101164670])

HSP 1 Score: 80.1073 bits (196), Expect = 7.327e-18
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Medaka
Match: rps27a (ribosomal protein S27a [Source:NCBI gene;Acc:101164670])

HSP 1 Score: 80.4925 bits (197), Expect = 1.161e-17
Identity = 44/76 (57.89%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++EP+D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Ensembl Medaka
Match: uba52 (ubiquitin A-52 residue ribosomal protein fusion product 1 [Source:NCBI gene;Acc:101169681])

HSP 1 Score: 77.0258 bits (188), Expect = 5.534e-17
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Planmine SMEST
Match: SMESG000035681.1 (SMESG000035681.1)

HSP 1 Score: 77.7962 bits (190), Expect = 2.210e-17
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVESSDSIENVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Planmine SMEST
Match: SMESG000066693.1 (SMESG000066693.1)

HSP 1 Score: 77.411 bits (189), Expect = 3.083e-17
Identity = 43/76 (56.58%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D +E +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVESSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

[Close]

BLAST of NEDD8 vs. Planmine SMEST
Match: SMESG000035995.1 (SMESG000035995.1)

HSP 1 Score: 82.8037 bits (203), Expect = 4.821e-17
Identity = 42/77 (54.55%), Postives = 59/77 (76.62%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGN 290
            M I VKTLTGK I +++EP+D +E +K +I+ KEG+PP QQRLI++GKQ+ND+  + E+ +  GS LHL L L+GGN
Sbjct:  134 MQIFVKTLTGKTITLEVEPSDTIESVKVKIQRKEGVPPVQQRLIWAGKQLNDNHTLLEFNVRKGSTLHLALRLKGGN 210

HSP 2 Score: 64.6994 bits (156), Expect = 4.252e-11
Identity = 35/74 (47.30%), Postives = 50/74 (67.57%), Query Frame = 3

Query:   66 IKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            I VKTL GK   +++   D +E++K + ++ EG PP QQRLIF+GKQ+ D + +++Y I   S LHL L LRGG
Sbjct:   60 IFVKTLNGKTNTLEVASGDTIEKVKAKSQDNEGFPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLGLRLRGG 133

[Close]

BLAST of NEDD8 vs. Planmine SMEST
Match: SMESG000058166.1 (SMESG000058166.1)

HSP 1 Score: 82.4185 bits (202), Expect = 7.231e-17
Identity = 42/77 (54.55%), Postives = 58/77 (75.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGN 290
            M I VKTLTGK I +++EP+D +E +K  I+ KEG+PP QQRLI++GKQ+ND+  + E+ +  GS LHL L L+GGN
Sbjct:  428 MQIFVKTLTGKTITLEVEPSDTIESVKVMIQRKEGVPPVQQRLIWAGKQLNDNHTLLEFNVRKGSTLHLALRLKGGN 504

HSP 2 Score: 66.6254 bits (161), Expect = 9.708e-12
Identity = 37/74 (50.00%), Postives = 52/74 (70.27%), Query Frame = 3

Query:   66 IKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            I VKTL GK I +++   D ++++K +I++KEGIPP QQRLIF+GKQ+ D   +++Y I     LHL L LRGG
Sbjct:  354 IFVKTLNGKTITLEVASGDTIKKVKAKIQDKEGIPPNQQRLIFTGKQLEDGHTLSDYNIRKEPTLHLGLQLRGG 427

[Close]

BLAST of NEDD8 vs. Planmine SMEST
Match: SMESG000025683.1 (SMESG000025683.1)

HSP 1 Score: 76.6406 bits (187), Expect = 1.008e-16
Identity = 42/76 (55.26%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D ++ +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:    1 MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 76

HSP 2 Score: 76.6406 bits (187), Expect = 1.008e-16
Identity = 42/76 (55.26%), Postives = 58/76 (76.32%), Query Frame = 3

Query:   60 MLIKVKTLTGKEIEIDIEPTDKVXXXXXXXXXXXGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGG 287
            M I VKTLTGK I +++E +D ++ +K +I++KEGIPP QQRLIF+GKQ+ D + +++Y I   S LHLVL LRGG
Sbjct:   77 MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 152

The following BLAST results are available for this feature:

BLAST of NEDD8 vs. Ensembl Human
BLAST of NEDD8 vs. Ensembl Celegans
BLAST of NEDD8 vs. Ensembl Fly
BLAST of NEDD8 vs. Ensembl Zebrafish
BLAST of NEDD8 vs. Ensembl Xenopus
BLAST of NEDD8 vs. Ensembl Mouse
BLAST of NEDD8 vs. UniProt/SwissProt
BLAST of NEDD8 vs. TrEMBL
BLAST of NEDD8 vs. Ensembl Cavefish
BLAST of NEDD8 vs. Ensembl Sea Lamprey
BLAST of NEDD8 vs. Ensembl Yeast
BLAST of NEDD8 vs. Ensembl Nematostella
BLAST of NEDD8 vs. Ensembl Medaka
BLAST of NEDD8 vs. Planmine SMEST

BLAST of NEDD8 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
NEDD8	1.227e-33	88.46	NEDD8 ubiquitin like modifier [Source:HGNC Symbol;...	[more]
NEDD8	1.227e-33	88.46	NEDD8 ubiquitin like modifier [Source:HGNC Symbol;...	[more]
NEDD8-MDP1	2.454e-23	88.71	NEDD8-MDP1 readthrough [Source:HGNC Symbol;Acc:HGN...	[more]
NEDD8-MDP1	2.454e-23	88.71	NEDD8-MDP1 readthrough [Source:HGNC Symbol;Acc:HGN...	[more]
UBB	2.354e-18	57.89	ubiquitin B [Source:HGNC Symbol;Acc:HGNC:12463]	[more]

BLAST of NEDD8 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ned-8	6.451e-32	84.21	NEDD8 [Source:UniProtKB/Swiss-Prot;Acc:Q93725]	[more]
ubq-2	3.860e-17	56.58	Ubiquitin-60S ribosomal protein L40 Ubiquitin 60S ...	[more]
ubq-1	2.564e-15	55.84	Polyubiquitin-A Ubiquitin Ubiquitin-related [Sourc...	[more]
ubq-1	2.564e-15	55.84	Polyubiquitin-A Ubiquitin Ubiquitin-related [Sourc...	[more]
ubq-1	3.500e-15	56.58	Polyubiquitin-A Ubiquitin Ubiquitin-related [Sourc...	[more]

BLAST of NEDD8 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Nedd8	1.000e-34	88.46	gene:FBgn0032725 transcript:FBtr0342928	[more]
Nedd8	1.000e-34	88.46	gene:FBgn0032725 transcript:FBtr0081192	[more]
RpL40	2.559e-18	57.89	gene:FBgn0003941 transcript:FBtr0334787	[more]
RpL40	2.559e-18	57.89	gene:FBgn0003941 transcript:FBtr0077470	[more]
RpS27A	7.854e-18	57.89	gene:FBgn0003942 transcript:FBtr0080016	[more]

BLAST of NEDD8 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nedd8l	1.907e-33	89.61	NEDD8 ubiquitin like modifier, like [Source:ZFIN;A...	[more]
nedd8	3.058e-33	89.61	NEDD8 ubiquitin like modifier [Source:ZFIN;Acc:ZDB...	[more]
nedd8l	9.694e-30	86.49	NEDD8 ubiquitin like modifier, like [Source:ZFIN;A...	[more]
ubb	2.111e-18	57.89	ubiquitin B [Source:ZFIN;Acc:ZDB-GENE-050411-10]	[more]
uba52	3.575e-18	57.89	ubiquitin A-52 residue ribosomal protein fusion pr...	[more]

BLAST of NEDD8 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nedd8	2.895e-33	90.79	neural precursor cell expressed, developmentally d...	[more]
uba52	5.252e-18	57.89	ubiquitin A-52 residue ribosomal protein fusion pr...	[more]
rps27a	1.066e-17	57.89	ribosomal protein S27a [Source:NCBI gene;Acc:54892...	[more]
ENSXETT00000033679.1	7.589e-17	57.89	ubiquitin C [Source:NCBI gene;Acc:448120]	[more]
pdcd11	1.334e-16	58.44	programmed cell death 11 [Source:Xenbase;Acc:XB-GE...	[more]

BLAST of NEDD8 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Nedd8	3.470e-28	89.71	neural precursor cell expressed, developmentally d...	[more]
Nedd8	3.470e-28	89.71	neural precursor cell expressed, developmentally d...	[more]
Gm8797	1.643e-18	57.89	predicted pseudogene 8797 [Source:MGI Symbol;Acc:M...	[more]
Uba52	1.845e-18	57.89	ubiquitin A-52 residue ribosomal protein fusion pr...	[more]
Gm11808	3.977e-18	57.89	predicted gene 11808 [Source:MGI Symbol;Acc:MGI:36...	[more]

BLAST of NEDD8 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9VJ33\|NEDD8_DROME	1.003e-33	88.46	NEDD8 OS=Drosophila melanogaster OX=7227 GN=Nedd8 ...	[more]
sp\|Q4PLJ0\|NEDD8_RABIT	5.891e-33	88.46	NEDD8 OS=Oryctolagus cuniculus OX=9986 GN=NEDD8 PE...	[more]
sp\|Q15843\|NEDD8_HUMAN	5.891e-33	88.46	NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1	[more]
sp\|P61282\|NEDD8_BOVIN	5.891e-33	88.46	NEDD8 OS=Bos taurus OX=9913 GN=NEDD8 PE=3 SV=1	[more]
sp\|Q93725\|NEDD8_CAEEL	8.206e-31	84.21	NEDD8 OS=Caenorhabditis elegans OX=6239 GN=ned-8 P...	[more]

BLAST of NEDD8 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A484BGE8	1.064e-31	90.91	Ubiquitin-like domain-containing protein OS=Drosop...	[more]
A0A3B0JBK2	1.104e-31	89.74	Blast:NEDD8 OS=Drosophila guanche OX=7266 GN=DGUA_...	[more]
B4I5M6	2.138e-31	88.46	GM17051 OS=Drosophila sechellia OX=7238 GN=Dsec\GM...	[more]
A0A1S3DU76	2.224e-31	89.74	NEDD8 OS=Diaphorina citri OX=121845 GN=LOC10352474...	[more]
Q29LT5	2.763e-31	88.46	Ubiquitin-like domain-containing protein OS=Drosop...	[more]

BLAST of NEDD8 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nedd8	1.478e-33	88.46	NEDD8 [Source:NCBI gene;Acc:103040682]	[more]
nedd8l	5.888e-33	88.31	NEDD8-like [Source:NCBI gene;Acc:103044361]	[more]
uba52	3.030e-18	57.89	ubiquitin A-52 residue ribosomal protein fusion pr...	[more]
uba52	3.030e-18	57.89	ubiquitin A-52 residue ribosomal protein fusion pr...	[more]
rps27a	6.733e-18	57.89	ribosomal protein S27a [Source:NCBI gene;Acc:10304...	[more]

BLAST of NEDD8 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3


Match Name	E-value	Identity	Description
UBB	2.093e-18	52.94	ubiquitin B [Source:HGNC Symbol;Acc:HGNC:12463]	[more]
ENSPMAT00000007011.1	3.480e-9	59.52	pep scaffold:Pmarinus_7.0:GL484716:14406:16135:-1 ...	[more]
zfand4	4.253e-8	38.20	zinc finger, AN1-type domain 4 [Source:ZFIN;Acc:ZD...	[more]

BLAST of NEDD8 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
RUB1	2.698e-19	59.74	Ubiquitin-like protein with similarity to mammalia...	[more]
RPL40B	7.742e-18	55.26	Ubiquitin-ribosomal 60S subunit protein L40B fusio...	[more]
RPL40A	7.742e-18	55.26	Ubiquitin-ribosomal 60S subunit protein L40A fusio...	[more]
UBI4	4.919e-17	55.84	Ubiquitin; becomes conjugated to proteins, marking...	[more]
RPS31	3.039e-14	52.86	Fusion protein cleaved to yield ribosomal protein ...	[more]

BLAST of NEDD8 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO45561	1.567e-18	57.89	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48503	2.757e-18	57.89	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32403	7.035e-18	57.14	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32547	2.292e-17	58.44	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31255	5.568e-13	53.85	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of NEDD8 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000033696.1	1.397e-29	86.84	pep primary_assembly:ASM223467v1:18:18100789:18102...	[more]
ENSORLT00000041155.1	5.434e-19	83.72	pep primary_assembly:ASM223467v1:17:17794475:17794...	[more]
rps27a	7.327e-18	57.89	ribosomal protein S27a [Source:NCBI gene;Acc:10116...	[more]
rps27a	1.161e-17	57.89	ribosomal protein S27a [Source:NCBI gene;Acc:10116...	[more]
uba52	5.534e-17	56.58	ubiquitin A-52 residue ribosomal protein fusion pr...	[more]

BLAST of NEDD8 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000035681.1	2.210e-17	56.58	SMESG000035681.1	[more]
SMESG000066693.1	3.083e-17	56.58	SMESG000066693.1	[more]
SMESG000035995.1	4.821e-17	54.55	SMESG000035995.1	[more]
SMESG000058166.1	7.231e-17	54.55	SMESG000058166.1	[more]
SMESG000025683.1	1.008e-16	55.26	SMESG000025683.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30011383 ID=SMED30011383|Name=NEDD8|organism=Schmidtea mediterranea sexual|type=transcript|length=1028bp
TTAAAATTTTAATAAAATTAATTTCTATTTTAGTCTTTTTTATATATACA
TTTATTGTGATGTTGATTAAAGTTAAAACTCTGACTGGTAAAGAAATTGA
AATAGATATAGAACCTACAGATAAGGTGGAGCGAATTAAAGAAAGAATAG
AAGAAAAAGAAGGTATACCACCTCAACAACAACGGTTGATATTTTCTGGG
AAACAAATGAATGATGACAAAGCAGTTGCTGAATATAAAATAATTGGTGG
TTCAGTTCTTCATTTAGTGTTGGCTTTACGAGGTGGTAATGCATTGTCAA
TCATTGAATAAATTGTTATTTTATTGCTAAAATTAATTTTCCTTTTACAA
ATTTCTATCAATTTAAATTTCTTCAGAATTTATTTAATTTAACGGTTTGT
TAGTATCTTCAATATTTTTAATGATTAGTGCAATATAATGATTGTTCTTG
TATAAAGTAAAGTTGGTTTAATTTGAAATTATTTTATTTTGCGTTTGTTA
ATTATATTTTTATGCATCGTTGTTCCTACATTGATAACTTGGTTTAATTT
TCATTTGTTTTTATGTAGTGTTAAGGAAACTAATTTCAAGAATGTGATTG
TTGGTCTTTGTAAAGCTGGAAAGTTATTTTTGGATTTGTATAATTCTTGC
TTACTGTTGTAGGCACTTTAAAAATATTATGCAAGATTTTCCAGTTTAAC
TGAAATTTTGATTTTTACGTATTTTATATACAAGTGTTAAATTCTTGAAC
CAATACAAAATGGAATCAAGTTTTTAATAAAAAGTAACTTAAAATTTCCA
ATGGTTTCATTTAAGATCAAAATGTGAAAATCAACAATCCCATTGAAAAA
AAAGTAGCATAAAAGTTAGATTAATTATCGTTCGACTAAATGAAATTTGT
ATATGAATATTTCAGGAATTTACAAGATAAAAATTTGATGTGATTTTGTG
TTATTATACAATGAATAAGTTGTCGTTTTAGTTTTATTATTATTTTGAAC
CTTATTAATAAATCTTAATAATGTTGGG

protein sequence of SMED30011383-orf-1

>SMED30011383-orf-1 ID=SMED30011383-orf-1|Name=SMED30011383-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=103bp
KILIKLISILVFFIYTFIVMLIKVKTLTGKEIEIDIEPTDKVERIKERIE
EKEGIPPQQQRLIFSGKQMNDDKAVAEYKIIGGSVLHLVLALRGGNALSI
IE*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000429	neoblast
PLANA:0002032	epidermal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR038738	Nedd8-like
IPR019956	Ubiquitin_dom
IPR000626	Ubiquitin-like_dom
IPR019954	Ubiquitin_CS
IPR029071	Ubiquitin-like_domsf

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0031386	protein tag

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus

Vocabulary: **biological process**
Term	Definition
GO:0007275	multicellular organism development
GO:0008283	cell proliferation
GO:0008589	regulation of smoothened signaling pathway
GO:0022008	neurogenesis
GO:0030162	regulation of proteolysis
GO:0030431	sleep
GO:0031647	regulation of protein stability
GO:0036099	female germ-line stem cell population maintenance
GO:0045116	protein neddylation
GO:0048812	neuron projection morphogenesis
GO:0051438	regulation of ubiquitin-protein transferase activity
GO:2000736	regulation of stem cell differentiation

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR019956	Ubiquitin domain	PRINTS	PR00348	UBIQUITIN	coord: 30..50 score: 34.89 coord: 72..93 score: 47.57 coord: 51..71 score: 73.83
IPR000626	Ubiquitin-like domain	SMART	SM00213	ubq_7	coord: 20..91 e-value: 1.3E-24 score: 97.8
IPR000626	Ubiquitin-like domain	PFAM	PF00240	ubiquitin	coord: 22..93 e-value: 4.7E-27 score: 93.5
IPR000626	Ubiquitin-like domain	PROSITE	PS50053	UBIQUITIN_2	coord: 20..95 score: 25.357
None	No IPR available	GENE3D	G3DSA:3.10.20.90		coord: 17..96 e-value: 1.2E-32 score: 113.6
None	No IPR available	PANTHER	PTHR10666	UBIQUITIN	coord: 19..98
None	No IPR available	PANTHER	PTHR10666:SF280	NEURAL PRECURSOR CELL-EXPRESSED, DEVELOPMENTALLY DOWN-REGULATED 8	coord: 19..98
None	No IPR available	TMHMM	TMhelix		coord: 2..24
IPR019954	Ubiquitin conserved site	PROSITE	PS00299	UBIQUITIN_1	coord: 46..71
IPR038738	Nedd8-like ubiquitin	CDD	cd01806	Ubl_NEDD8	coord: 22..95 e-value: 1.58279E-47 score: 144.454
IPR029071	Ubiquitin-like domain superfamily	SUPERFAMILY	SSF54236	Ubiquitin-like	coord: 18..95