Serine palmitoyltransferase 1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30011350 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Human
Match: SPTLC1 (serine palmitoyltransferase long chain base subunit 1 [Source:HGNC Symbol;Acc:HGNC:11277]) HSP 1 Score: 407.527 bits (1046), Expect = 3.041e-137 Identity = 228/462 (49.35%), Postives = 306/462 (66.23%), Query Frame = 3
Query: 129 PTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGV--AQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEER------LEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVGE 1490
P YHL+ E +LI+ + L FS++YK E LT KE+EELI +W+PEPLVP P +++S G + K +N ASFNF L+ N ++ A +L+KYGVG+CGPRGFYGTFDVHL LED +A FM EE+++YSYGF+T+ASAIPAY+KRGD++F D FAIQ GL ASRS IK FKHNDM L LL+EQ E KNP KAR+TR FIV+EGLYMN G ICPLP++V+LKYKYK RIFL+E+LSFGVLG+HGRGVT+H+G+++ DIDLI+ ++E ALA+ GGF G +V+DHQRLSGQGYCFSASLPPLLA A L ++ G+ + + +I K + + K+ E +SP H++L +T R L++ V+ + +T+ARYL++ E P PSIR+ + T+EE+E + ++ V +
Sbjct: 21 PAYHLILEGILILWIIRLLFSKTYKLQERSDLTVKEKEELIEEWQPEPLVP----PVPKDHPALNYNIVS--GPPSHKTVVNGKECINFASFNFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDRAACFAIQKGLQASRSDIKLFKHNDMADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENPGIFAVLKEKCGQIHKALQGI------SGLKVVGESLSPAFHLQLE-ESTGSREQDVRLLQEIVDQCMNRSIALTQARYLEKEEKCLPPPSIRVVVTVEQTEEELERAASTIKEVAQ 469
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Human
Match: SPTLC2 (serine palmitoyltransferase long chain base subunit 2 [Source:HGNC Symbol;Acc:HGNC:11278]) HSP 1 Score: 160.999 bits (406), Expect = 1.750e-43 Identity = 89/276 (32.25%), Postives = 144/276 (52.17%), Query Frame = 3
Query: 360 FNENKTKPVLNLASFNFFNLIGNE-KINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQ---SEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVA 1175
+ N K V+N+ S+N+ N E A K L +YG G C R G D H +LE+ +A F+ E ++ Y GF+T + IPA +G +I +DE ++ G S + I+ FKHN+M L LL++ + + P K + I++EG+Y G I LP+++ LK KYK ++LDE S G LG GRGV ++FG+D D+D++ G+ + GG+ G K ++D+ R ++ SL P + ++ I ++G +
Sbjct: 99 YTGNIIKGVINMGSYNYLGFARNTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEELEELVARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWK----KILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSLSPPVVEQIITSMKCIMGQDGTS 370
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Human
Match: SPTLC2 (serine palmitoyltransferase long chain base subunit 2 [Source:HGNC Symbol;Acc:HGNC:11278]) HSP 1 Score: 160.614 bits (405), Expect = 3.533e-42 Identity = 89/276 (32.25%), Postives = 144/276 (52.17%), Query Frame = 3
Query: 360 FNENKTKPVLNLASFNFFNLIGNE-KINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQ---SEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVA 1175
+ N K V+N+ S+N+ N E A K L +YG G C R G D H +LE+ +A F+ E ++ Y GF+T + IPA +G +I +DE ++ G S + I+ FKHN+M L LL++ + + P K + I++EG+Y G I LP+++ LK KYK ++LDE S G LG GRGV ++FG+D D+D++ G+ + GG+ G K ++D+ R ++ SL P + ++ I ++G +
Sbjct: 162 YTGNIIKGVINMGSYNYLGFARNTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEELEELVARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWK----KILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSLSPPVVEQIITSMKCIMGQDGTS 433
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Human
Match: SPTLC3 (serine palmitoyltransferase long chain base subunit 3 [Source:HGNC Symbol;Acc:HGNC:16253]) HSP 1 Score: 158.688 bits (400), Expect = 1.218e-41 Identity = 93/286 (32.52%), Postives = 152/286 (53.15%), Query Frame = 3
Query: 360 FNENKTKPVLNLASFNFFNLIGN-EKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARIT--RTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRI-RLNEISK 1205
F K V+N+ S+NF L ++ T + L YG G R GT D H +LED +A F+N E ++V+ GF+T + IPA +G +I +DE ++ G S + I+ FKHN+ L LL + I + R + I++EG+Y G I LP+I+ LK KYK +++DE S G +G GRGVT+ FG+D ++D++ G+ + GG+ G K +VD+ R+ +++S+ P +A L++I +G Q + R+ +++K
Sbjct: 154 FTGRVIKDVINMGSYNFLGLAAKYDESMRTIKDVLEVYGTGVASTRHEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNTQSLEKLLRDA---VIYGQPRTRRAWKKILILVEGVYSMEGSIVHLPQIIALKKKYKAYLYIDEAHSIGAVGPTGRGVTEFFGLDPHEVDVLMGTFTKSFGASGGYIAGRKDLVDYLRVHSHSAVYASSMSPPIAEQIIRSLKLIMGLDGTTQGLQRVQQLAK 436
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Human
Match: ALAS2 (5'-aminolevulinate synthase 2 [Source:HGNC Symbol;Acc:HGNC:397]) HSP 1 Score: 130.183 bits (326), Expect = 1.662e-31 Identity = 83/288 (28.82%), Postives = 146/288 (50.69%), Query Frame = 3
Query: 375 TKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAK--RGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSR 1232
+K V S ++ + + ++ + Q+ L+++G G+ G R GT H++LE E+A + ++++S F S + AK G I++D G ++ G+ S + F+HND DHL LLE+ NP +I + E ++ G ICPL ++ ++ ++Y F+DE + G+ G G G+ + G+ + ID+I+G+L A GG+ ++ +VD R G+ F+ SLPP++ GA + +++ EEG A R K + LL R
Sbjct: 188 SKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEK------SNPKIPKI----VAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGI-MHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDR 464
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Celegans
Match: sptl-1 (Serine palmitoyltransferase 1 [Source:UniProtKB/Swiss-Prot;Acc:P91079]) HSP 1 Score: 415.616 bits (1067), Expect = 1.999e-141 Identity = 212/406 (52.22%), Postives = 279/406 (68.72%), Query Frame = 3
Query: 252 ADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIR---LNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEG-LLITEARYLKESEYKCPKPSIRLSINCALTDEEIE 1457
ADW PEPLVP+ Q + ++ K+ + GK+ + LN+AS NF + IG ++I + A++ + KYGVGSCGPRGFYGT DVHL LE E+A FM CEE+V+YSYGF+TV+SAIPAYAK+GDVIF DEGV+FAIQ GL ASRS+++YFKHNDM+HL LL EQ + K+P KA+ R FIV+EGLY+NY D+CPLPKI+E K+++KVR+F+DE+ SFGV+G GRGVT+HF V + D+D++ SLE ALA+ GGF VG YVV HQRLSG GYCFSASLPPLLA AS + +I E Q++ +N K +L S+ S L SP+KHI + E++L+ V + + LL+T ARYL + E +PSIR+ LT+EEI+
Sbjct: 26 ADWTPEPLVPETPQDHPVLNPKY------ADGKMTKDVSIDGEKYLNMASTNFLSFIGVKRIEDRAKQTIFKYGVGSCGPRGFYGTVDVHLDLEKELAKFMGCEEAVLYSYGFATVSSAIPAYAKKGDVIFVDEGVNFAIQKGLQASRSRVEYFKHNDMEHLERLLLEQEQRDKKDPKKAKSVRRFIVVEGLYVNYADLCPLPKIIEFKWRFKVRVFIDESWSFGVIGKTGRGVTEHFNVPMEDVDMVMASLENALASTGGFCVGRSYVVGHQRLSGLGYCFSASLPPLLATAASEAISIIDEEPSRVQKVTEMAINGQKKLQDALSGSKFS----LQGCPESPMKHIYYNGEDEEKQLDTFVETVFTKNHLLLTRARYLDKDELFKIRPSIRVMFQHDLTEEEIQ 421
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Celegans
Match: sptl-1 (Serine palmitoyltransferase 1 [Source:UniProtKB/Swiss-Prot;Acc:P91079]) HSP 1 Score: 415.616 bits (1067), Expect = 1.999e-141 Identity = 212/406 (52.22%), Postives = 279/406 (68.72%), Query Frame = 3
Query: 252 ADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIR---LNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEG-LLITEARYLKESEYKCPKPSIRLSINCALTDEEIE 1457
ADW PEPLVP+ Q + ++ K+ + GK+ + LN+AS NF + IG ++I + A++ + KYGVGSCGPRGFYGT DVHL LE E+A FM CEE+V+YSYGF+TV+SAIPAYAK+GDVIF DEGV+FAIQ GL ASRS+++YFKHNDM+HL LL EQ + K+P KA+ R FIV+EGLY+NY D+CPLPKI+E K+++KVR+F+DE+ SFGV+G GRGVT+HF V + D+D++ SLE ALA+ GGF VG YVV HQRLSG GYCFSASLPPLLA AS + +I E Q++ +N K +L S+ S L SP+KHI + E++L+ V + + LL+T ARYL + E +PSIR+ LT+EEI+
Sbjct: 26 ADWTPEPLVPETPQDHPVLNPKY------ADGKMTKDVSIDGEKYLNMASTNFLSFIGVKRIEDRAKQTIFKYGVGSCGPRGFYGTVDVHLDLEKELAKFMGCEEAVLYSYGFATVSSAIPAYAKKGDVIFVDEGVNFAIQKGLQASRSRVEYFKHNDMEHLERLLLEQEQRDKKDPKKAKSVRRFIVVEGLYVNYADLCPLPKIIEFKWRFKVRVFIDESWSFGVIGKTGRGVTEHFNVPMEDVDMVMASLENALASTGGFCVGRSYVVGHQRLSGLGYCFSASLPPLLATAASEAISIIDEEPSRVQKVTEMAINGQKKLQDALSGSKFS----LQGCPESPMKHIYYNGEDEEKQLDTFVETVFTKNHLLLTRARYLDKDELFKIRPSIRVMFQHDLTEEEIQ 421
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Celegans
Match: sptl-1 (Serine palmitoyltransferase 1 [Source:UniProtKB/Swiss-Prot;Acc:P91079]) HSP 1 Score: 415.616 bits (1067), Expect = 1.999e-141 Identity = 212/406 (52.22%), Postives = 279/406 (68.72%), Query Frame = 3
Query: 252 ADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIR---LNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEG-LLITEARYLKESEYKCPKPSIRLSINCALTDEEIE 1457
ADW PEPLVP+ Q + ++ K+ + GK+ + LN+AS NF + IG ++I + A++ + KYGVGSCGPRGFYGT DVHL LE E+A FM CEE+V+YSYGF+TV+SAIPAYAK+GDVIF DEGV+FAIQ GL ASRS+++YFKHNDM+HL LL EQ + K+P KA+ R FIV+EGLY+NY D+CPLPKI+E K+++KVR+F+DE+ SFGV+G GRGVT+HF V + D+D++ SLE ALA+ GGF VG YVV HQRLSG GYCFSASLPPLLA AS + +I E Q++ +N K +L S+ S L SP+KHI + E++L+ V + + LL+T ARYL + E +PSIR+ LT+EEI+
Sbjct: 26 ADWTPEPLVPETPQDHPVLNPKY------ADGKMTKDVSIDGEKYLNMASTNFLSFIGVKRIEDRAKQTIFKYGVGSCGPRGFYGTVDVHLDLEKELAKFMGCEEAVLYSYGFATVSSAIPAYAKKGDVIFVDEGVNFAIQKGLQASRSRVEYFKHNDMEHLERLLLEQEQRDKKDPKKAKSVRRFIVVEGLYVNYADLCPLPKIIEFKWRFKVRVFIDESWSFGVIGKTGRGVTEHFNVPMEDVDMVMASLENALASTGGFCVGRSYVVGHQRLSGLGYCFSASLPPLLATAASEAISIIDEEPSRVQKVTEMAINGQKKLQDALSGSKFS----LQGCPESPMKHIYYNGEDEEKQLDTFVETVFTKNHLLLTRARYLDKDELFKIRPSIRVMFQHDLTEEEIQ 421
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Celegans
Match: sptl-1 (Serine palmitoyltransferase 1 [Source:UniProtKB/Swiss-Prot;Acc:P91079]) HSP 1 Score: 415.616 bits (1067), Expect = 4.030e-141 Identity = 212/406 (52.22%), Postives = 278/406 (68.47%), Query Frame = 3
Query: 252 ADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIR---LNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEG-LLITEARYLKESEYKCPKPSIRLSINCALTDEEIE 1457
ADW PEPLVP+ Q + ++ K+ GK+ + LN+AS NF + IG ++I + A++ + KYGVGSCGPRGFYGT DVHL LE E+A FM CEE+V+YSYGF+TV+SAIPAYAK+GDVIF DEGV+FAIQ GL ASRS+++YFKHNDM+HL LL EQ + K+P KA+ R FIV+EGLY+NY D+CPLPKI+E K+++KVR+F+DE+ SFGV+G GRGVT+HF V + D+D++ SLE ALA+ GGF VG YVV HQRLSG GYCFSASLPPLLA AS + +I E Q++ +N K +L S+ S L SP+KHI + E++L+ V + + LL+T ARYL + E +PSIR+ LT+EEI+
Sbjct: 50 ADWTPEPLVPETPQDHPVLNPKYAD------GKMTKDVSIDGEKYLNMASTNFLSFIGVKRIEDRAKQTIFKYGVGSCGPRGFYGTVDVHLDLEKELAKFMGCEEAVLYSYGFATVSSAIPAYAKKGDVIFVDEGVNFAIQKGLQASRSRVEYFKHNDMEHLERLLLEQEQRDKKDPKKAKSVRRFIVVEGLYVNYADLCPLPKIIEFKWRFKVRVFIDESWSFGVIGKTGRGVTEHFNVPMEDVDMVMASLENALASTGGFCVGRSYVVGHQRLSGLGYCFSASLPPLLATAASEAISIIDEEPSRVQKVTEMAINGQKKLQDALSGSKFS----LQGCPESPMKHIYYNGEDEEKQLDTFVETVFTKNHLLLTRARYLDKDELFKIRPSIRVMFQHDLTEEEIQ 445
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Celegans
Match: sptl-1 (Serine palmitoyltransferase 1 [Source:UniProtKB/Swiss-Prot;Acc:P91079]) HSP 1 Score: 415.616 bits (1067), Expect = 4.030e-141 Identity = 212/406 (52.22%), Postives = 278/406 (68.47%), Query Frame = 3
Query: 252 ADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIR---LNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEG-LLITEARYLKESEYKCPKPSIRLSINCALTDEEIE 1457
ADW PEPLVP+ Q + ++ K+ GK+ + LN+AS NF + IG ++I + A++ + KYGVGSCGPRGFYGT DVHL LE E+A FM CEE+V+YSYGF+TV+SAIPAYAK+GDVIF DEGV+FAIQ GL ASRS+++YFKHNDM+HL LL EQ + K+P KA+ R FIV+EGLY+NY D+CPLPKI+E K+++KVR+F+DE+ SFGV+G GRGVT+HF V + D+D++ SLE ALA+ GGF VG YVV HQRLSG GYCFSASLPPLLA AS + +I E Q++ +N K +L S+ S L SP+KHI + E++L+ V + + LL+T ARYL + E +PSIR+ LT+EEI+
Sbjct: 50 ADWTPEPLVPETPQDHPVLNPKYAD------GKMTKDVSIDGEKYLNMASTNFLSFIGVKRIEDRAKQTIFKYGVGSCGPRGFYGTVDVHLDLEKELAKFMGCEEAVLYSYGFATVSSAIPAYAKKGDVIFVDEGVNFAIQKGLQASRSRVEYFKHNDMEHLERLLLEQEQRDKKDPKKAKSVRRFIVVEGLYVNYADLCPLPKIIEFKWRFKVRVFIDESWSFGVIGKTGRGVTEHFNVPMEDVDMVMASLENALASTGGFCVGRSYVVGHQRLSGLGYCFSASLPPLLATAASEAISIIDEEPSRVQKVTEMAINGQKKLQDALSGSKFS----LQGCPESPMKHIYYNGEDEEKQLDTFVETVFTKNHLLLTRARYLDKDELFKIRPSIRVMFQHDLTEEEIQ 445
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Fly
Match: Spt-I (gene:FBgn0086532 transcript:FBtr0087731) HSP 1 Score: 382.104 bits (980), Expect = 1.078e-127 Identity = 216/469 (46.06%), Postives = 302/469 (64.39%), Query Frame = 3
Query: 105 ITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLR--LNNTEERLEKAVNLAYQ---EGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVGENL 1496
I S PT+ LV E +L+I+ ++L +LTK+EE+ +IAD++PEPLV D + ++ ++ V S GK + + + LNL S N+ + +++I E A K+LRKYGVGSCGPRGFYGT DVHL LED IA FM EE++VYSYGFSTVASAIPAYAKRGD+IF DE V+FAIQ GL ASRS I +FKHND++ L LL EQ + KNP KA TR F+V EG+YMN G+ICPLP +V L+ KYK+R+F+DE++SFG LG G GVT+HF VD ++DLI+ +E ++AT GGF VGS ++ +HQRLSG GY FSASLPP+L A L+ E + ++++ + L S+L+ L +++SP+KH+ L N ++ L+ LA + G+ + +A YL+ E + +PSIR+++N L EI+ V+E V ++
Sbjct: 10 IGSIFRNTPTFALVLETLLLITVIWLLL-HRRGGGRRRQLTKEEEDRIIADYEPEPLVADTDPNHPLLHTRV---VQSRVGKRIQVDGHDC---LNLGSHNYLGFLEDQEILEEACKSLRKYGVGSCGPRGFYGTMDVHLDLEDRIAKFMGLEEAIVYSYGFSTVASAIPAYAKRGDLIFVDEAVNFAIQKGLDASRSTIVFFKHNDVEDLERLLIEQEKRDQKNPKKAAKTRRFLVAEGIYMNTGEICPLPDLVALRQKYKLRLFIDESISFGTLGQGGHGVTEHFNVDRDEVDLISAGMEGSMATVGGFCVGSHFIAEHQRLSGLGYIFSASLPPMLTQAAISALDRFEREPQIFEQLQAKSKTLHQKFLRFSKLT----LRGDEVSPVKHLYLAQPAENFDKELKLLTELADKCIARGVAVVQAAYLQNRERQPVRPSIRIAVNRLLESSEIDNAFEVIESVSSSV 467
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Fly
Match: Spt-I (gene:FBgn0086532 transcript:FBtr0087729) HSP 1 Score: 382.104 bits (980), Expect = 1.078e-127 Identity = 216/469 (46.06%), Postives = 302/469 (64.39%), Query Frame = 3
Query: 105 ITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLR--LNNTEERLEKAVNLAYQ---EGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVGENL 1496
I S PT+ LV E +L+I+ ++L +LTK+EE+ +IAD++PEPLV D + ++ ++ V S GK + + + LNL S N+ + +++I E A K+LRKYGVGSCGPRGFYGT DVHL LED IA FM EE++VYSYGFSTVASAIPAYAKRGD+IF DE V+FAIQ GL ASRS I +FKHND++ L LL EQ + KNP KA TR F+V EG+YMN G+ICPLP +V L+ KYK+R+F+DE++SFG LG G GVT+HF VD ++DLI+ +E ++AT GGF VGS ++ +HQRLSG GY FSASLPP+L A L+ E + ++++ + L S+L+ L +++SP+KH+ L N ++ L+ LA + G+ + +A YL+ E + +PSIR+++N L EI+ V+E V ++
Sbjct: 10 IGSIFRNTPTFALVLETLLLITVIWLLL-HRRGGGRRRQLTKEEEDRIIADYEPEPLVADTDPNHPLLHTRV---VQSRVGKRIQVDGHDC---LNLGSHNYLGFLEDQEILEEACKSLRKYGVGSCGPRGFYGTMDVHLDLEDRIAKFMGLEEAIVYSYGFSTVASAIPAYAKRGDLIFVDEAVNFAIQKGLDASRSTIVFFKHNDVEDLERLLIEQEKRDQKNPKKAAKTRRFLVAEGIYMNTGEICPLPDLVALRQKYKLRLFIDESISFGTLGQGGHGVTEHFNVDRDEVDLISAGMEGSMATVGGFCVGSHFIAEHQRLSGLGYIFSASLPPMLTQAAISALDRFEREPQIFEQLQAKSKTLHQKFLRFSKLT----LRGDEVSPVKHLYLAQPAENFDKELKLLTELADKCIARGVAVVQAAYLQNRERQPVRPSIRIAVNRLLESSEIDNAFEVIESVSSSV 467
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Fly
Match: Spt-I (gene:FBgn0086532 transcript:FBtr0087730) HSP 1 Score: 382.104 bits (980), Expect = 1.078e-127 Identity = 216/469 (46.06%), Postives = 302/469 (64.39%), Query Frame = 3
Query: 105 ITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLR--LNNTEERLEKAVNLAYQ---EGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVGENL 1496
I S PT+ LV E +L+I+ ++L +LTK+EE+ +IAD++PEPLV D + ++ ++ V S GK + + + LNL S N+ + +++I E A K+LRKYGVGSCGPRGFYGT DVHL LED IA FM EE++VYSYGFSTVASAIPAYAKRGD+IF DE V+FAIQ GL ASRS I +FKHND++ L LL EQ + KNP KA TR F+V EG+YMN G+ICPLP +V L+ KYK+R+F+DE++SFG LG G GVT+HF VD ++DLI+ +E ++AT GGF VGS ++ +HQRLSG GY FSASLPP+L A L+ E + ++++ + L S+L+ L +++SP+KH+ L N ++ L+ LA + G+ + +A YL+ E + +PSIR+++N L EI+ V+E V ++
Sbjct: 10 IGSIFRNTPTFALVLETLLLITVIWLLL-HRRGGGRRRQLTKEEEDRIIADYEPEPLVADTDPNHPLLHTRV---VQSRVGKRIQVDGHDC---LNLGSHNYLGFLEDQEILEEACKSLRKYGVGSCGPRGFYGTMDVHLDLEDRIAKFMGLEEAIVYSYGFSTVASAIPAYAKRGDLIFVDEAVNFAIQKGLDASRSTIVFFKHNDVEDLERLLIEQEKRDQKNPKKAAKTRRFLVAEGIYMNTGEICPLPDLVALRQKYKLRLFIDESISFGTLGQGGHGVTEHFNVDRDEVDLISAGMEGSMATVGGFCVGSHFIAEHQRLSGLGYIFSASLPPMLTQAAISALDRFEREPQIFEQLQAKSKTLHQKFLRFSKLT----LRGDEVSPVKHLYLAQPAENFDKELKLLTELADKCIARGVAVVQAAYLQNRERQPVRPSIRIAVNRLLESSEIDNAFEVIESVSSSV 467
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Fly
Match: lace (gene:FBgn0002524 transcript:FBtr0343735) HSP 1 Score: 146.362 bits (368), Expect = 2.124e-37 Identity = 85/284 (29.93%), Postives = 146/284 (51.41%), Query Frame = 3
Query: 330 VISSFGKIVYFNENKTKPVLNLASFNFFNLIG-NEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKA--RITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGV 1172
V +G F +T+ LNL S+N+ + + ++++ R G+ C R G + +LE A + E+++V+ GF+T A +P+ ++ +DE +I GL S + K FKHN+M L +L + NP K + I++EG++ G I LP+++ LK KYK ++LDE S G +G GRGVTD+F VD ++D++ G+ + + GG+ GSK ++D R + +C++AS+ P +A ++ I E+G
Sbjct: 198 VTDDYGWSFKFTGTETR-CLNLGSYNYLGFAAATGQCADDSEESARSSGLAYCSSRCELGDNEQLQELEALTARYFGVEDAIVFGMGFATNALNLPSLLGPNSLVISDEKNHASIILGLRLSGATTKVFKHNNMRDLERVLRQGV--CYGNPKKGGQPWDKVMILVEGIFSMEGSIVRLPEVIALKKKYKAYLYLDEAHSVGAMGSRGRGVTDYFNVDPKEVDILMGTFTKSFGSAGGYLAGSKKLIDFLRTNSHAHCYAASISPPIAQQILTSMKTIMGEDGT 478
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Fly
Match: lace (gene:FBgn0002524 transcript:FBtr0080738) HSP 1 Score: 146.362 bits (368), Expect = 2.124e-37 Identity = 85/284 (29.93%), Postives = 146/284 (51.41%), Query Frame = 3
Query: 330 VISSFGKIVYFNENKTKPVLNLASFNFFNLIG-NEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKA--RITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGV 1172
V +G F +T+ LNL S+N+ + + ++++ R G+ C R G + +LE A + E+++V+ GF+T A +P+ ++ +DE +I GL S + K FKHN+M L +L + NP K + I++EG++ G I LP+++ LK KYK ++LDE S G +G GRGVTD+F VD ++D++ G+ + + GG+ GSK ++D R + +C++AS+ P +A ++ I E+G
Sbjct: 198 VTDDYGWSFKFTGTETR-CLNLGSYNYLGFAAATGQCADDSEESARSSGLAYCSSRCELGDNEQLQELEALTARYFGVEDAIVFGMGFATNALNLPSLLGPNSLVISDEKNHASIILGLRLSGATTKVFKHNNMRDLERVLRQGV--CYGNPKKGGQPWDKVMILVEGIFSMEGSIVRLPEVIALKKKYKAYLYLDEAHSVGAMGSRGRGVTDYFNVDPKEVDILMGTFTKSFGSAGGYLAGSKKLIDFLRTNSHAHCYAASISPPIAQQILTSMKTIMGEDGT 478
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Zebrafish
Match: sptlc1 (serine palmitoyltransferase, long chain base subunit 1 [Source:ZFIN;Acc:ZDB-GENE-050522-61]) HSP 1 Score: 419.468 bits (1077), Expect = 4.296e-142 Identity = 231/461 (50.11%), Postives = 308/461 (66.81%), Query Frame = 3
Query: 99 ELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISS--FGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEER------LEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIE 1457
E++ +F P YHL+ E LI+ + L FS++YK E LT+KE+EELI +W+PEPLV P V++ KI+ K +N ASFNF L+ NE++ A +L+KYGVG+CGPRGFYGTFDVHL+LE+ +A FM EE+++YSYGF+T+ASAIPAY+KRGD+IF DE F+IQ GL ASRS IKYFKHNDM+ L LL+EQ E KNP KAR+ R FI++EGLY+N DICPLP++V+LKYKYKVRIFL+E++SFGVLG+HGRGVT+HFGV++ DIDLI+ ++E ALA+ GGF G +V+DHQRLSGQGYCFSASLPP+LA A L ++ + G+ + +R E + + L + K+ E +P H++L N+T R L V+ + + +T ARYL + E P PSIR+ + T EEIE
Sbjct: 11 EMVQAFYE-APAYHLILEGFLILWIIRLLFSKTYKLQERSDLTEKEKEELIEEWQPEPLV----SPVSKDHPSLNYDVVTGPPSHKIIV----NGKECINFASFNFLGLLDNERVKLKALASLKKYGVGTCGPRGFYGTFDVHLELEERLAKFMRTEEAIIYSYGFATIASAIPAYSKRGDIIFVDEAACFSIQKGLQASRSFIKYFKHNDMEDLERLLKEQEIEDQKNPRKARVIRRFILVEGLYINTADICPLPELVKLKYKYKVRIFLEESMSFGVLGEHGRGVTEHFGVNIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPMLAAAAIEALNIMEEDPGIFRVLR--EKCRNVHKALQGTAGL--KVVGESFAPALHLQLE-NSTGSRVNDLKLLRAIVDYSLDRQVALTLARYLDKEERFLPPPSIRVVVTVEQTQEEIE 457
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Zebrafish
Match: sptlc1 (serine palmitoyltransferase, long chain base subunit 1 [Source:ZFIN;Acc:ZDB-GENE-050522-61]) HSP 1 Score: 419.468 bits (1077), Expect = 5.072e-142 Identity = 233/473 (49.26%), Postives = 312/473 (65.96%), Query Frame = 3
Query: 63 INMESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISS--FGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEER------LEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIE 1457
+ M S + E++ +F P YHL+ E LI+ + L FS++YK E LT+KE+EELI +W+PEPLV P V++ KI+ K +N ASFNF L+ NE++ A +L+KYGVG+CGPRGFYGTFDVHL+LE+ +A FM EE+++YSYGF+T+ASAIPAY+KRGD+IF DE F+IQ GL ASRS IKYFKHNDM+ L LL+EQ E KNP KAR+ R FI++EGLY+N DICPLP++V+LKYKYKVRIFL+E++SFGVLG+HGRGVT+HFGV++ DIDLI+ ++E ALA+ GGF G +V+DHQRLSGQGYCFSASLPP+LA A L ++ + G+ + +R E + + L + K+ E +P H++L N+T R L V+ + + +T ARYL + E P PSIR+ + T EEIE
Sbjct: 11 VKMASGQQWVLVEMVQAFYE-APAYHLILEGFLILWIIRLLFSKTYKLQERSDLTEKEKEELIEEWQPEPLV----SPVSKDHPSLNYDVVTGPPSHKIIV----NGKECINFASFNFLGLLDNERVKLKALASLKKYGVGTCGPRGFYGTFDVHLELEERLAKFMRTEEAIIYSYGFATIASAIPAYSKRGDIIFVDEAACFSIQKGLQASRSFIKYFKHNDMEDLERLLKEQEIEDQKNPRKARVIRRFILVEGLYINTADICPLPELVKLKYKYKVRIFLEESMSFGVLGEHGRGVTEHFGVNIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPMLAAAAIEALNIMEEDPGIFRVLR--EKCRNVHKALQGTAGL--KVVGESFAPALHLQLE-NSTGSRVNDLKLLRAIVDYSLDRQVALTLARYLDKEERFLPPPSIRVVVTVEQTQEEIE 469
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Zebrafish
Match: sptlc1 (serine palmitoyltransferase, long chain base subunit 1 [Source:ZFIN;Acc:ZDB-GENE-050522-61]) HSP 1 Score: 419.468 bits (1077), Expect = 9.729e-142 Identity = 233/473 (49.26%), Postives = 312/473 (65.96%), Query Frame = 3
Query: 63 INMESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISS--FGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEER------LEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIE 1457
+ M S + E++ +F P YHL+ E LI+ + L FS++YK E LT+KE+EELI +W+PEPLV P V++ KI+ K +N ASFNF L+ NE++ A +L+KYGVG+CGPRGFYGTFDVHL+LE+ +A FM EE+++YSYGF+T+ASAIPAY+KRGD+IF DE F+IQ GL ASRS IKYFKHNDM+ L LL+EQ E KNP KAR+ R FI++EGLY+N DICPLP++V+LKYKYKVRIFL+E++SFGVLG+HGRGVT+HFGV++ DIDLI+ ++E ALA+ GGF G +V+DHQRLSGQGYCFSASLPP+LA A L ++ + G+ + +R E + + L + K+ E +P H++L N+T R L V+ + + +T ARYL + E P PSIR+ + T EEIE
Sbjct: 25 VKMASGQQWVLVEMVQAFYE-APAYHLILEGFLILWIIRLLFSKTYKLQERSDLTEKEKEELIEEWQPEPLV----SPISKDHPSLNYDVVTGPPSHKIIV----NGKECINFASFNFLGLLDNERVKLKALASLKKYGVGTCGPRGFYGTFDVHLELEERLAKFMRTEEAIIYSYGFATIASAIPAYSKRGDIIFVDEAACFSIQKGLQASRSFIKYFKHNDMEDLERLLKEQEIEDQKNPRKARVIRRFILVEGLYINTADICPLPELVKLKYKYKVRIFLEESMSFGVLGEHGRGVTEHFGVNIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPMLAAAAIEALNIMEEDPGIFRVLR--EKCRNVHKALQGTAGL--KVVGESFAPALHLQLE-NSTGSRVNDLKLLRAIVDYSLDRQVALTLARYLDKEERFLPPPSIRVVVTVEQTQEEIE 483
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Zebrafish
Match: sptlc2b (serine palmitoyltransferase, long chain base subunit 2b [Source:ZFIN;Acc:ZDB-GENE-080305-8]) HSP 1 Score: 162.155 bits (409), Expect = 5.555e-43 Identity = 94/284 (33.10%), Postives = 148/284 (52.11%), Query Frame = 3
Query: 378 KPVLNLASFNFFNLIGNEKI-NETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEE---QSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVA-QRIRLNEISKKIS 1214
K V+N+ S+N+ N + A + KYGVG R G D H +LE +A F+ E S+V+ GF+T + IPA +G +I +DE ++ G S S I+ FKHN+M L +L + + P K + IV+EG+Y G I LP+I+ LK KYK ++LDE S G LG GRGV D+FG+D +D+D++ G+ + GG+ G K ++D+ RL ++ S+ P + ++ I E+G + RL ++S+ +
Sbjct: 167 KDVINMGSYNYLGFAENSGTCADAAAYSTVKYGVGVSSTRQEIGNLDKHEELEKLVARFLGVESSMVFGMGFATNSMNIPALTGKGCLILSDELNHASLVLGARLSGSTIRVFKHNNMQSLEKMLRDAIVHGQPRTHRPWK----KILIVVEGIYSMEGSIVRLPEIIALKKKYKAYLYLDEAHSIGALGTRGRGVVDYFGLDPSDVDIMMGTFTKSFGAAGGYIGGKKELIDYLRLHSHSAVYATSMSPPVTQQIITSMKCIMGEDGTTLGQERLRQLSENTT 446
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Zebrafish
Match: sptlc3 (serine palmitoyltransferase, long chain base subunit 3 [Source:ZFIN;Acc:ZDB-GENE-041210-281]) HSP 1 Score: 159.073 bits (401), Expect = 6.978e-42 Identity = 92/264 (34.85%), Postives = 146/264 (55.30%), Query Frame = 3
Query: 384 VLNLASFNFFNLIGNE-KINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTF----IVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRA 1160
V+N+ S+N+ N +T + R+YGVG C R G F +H +LE +A+F+ E ++ + GF+T + IPA +G +I +DE ++ G S + I+ FKHN+M L LL+E AI + + R R++ I++EG+Y G + LP+I+ LK KYK ++LDE S G +G GRGVT+HFGVD +ID++ G+ + GG+ G K +VD+ R ++ ++ P VV ++IRA
Sbjct: 163 VINMGSYNYLGFAENNVDFLKTVAEKTRQYGVGVCSTRQELGNFSIHEELEHLVADFLGVESAMAFGMGFATNSMNIPALVGKGCLILSDELNHTSLILGARLSGATIRVFKHNNMQSLEKLLKE----AICS-GQPRTHRSWKKILIMVEGIYSMEGSLVRLPEIIALKKKYKAYLYLDEAHSIGAVGPTGRGVTEHFGVDPKEIDVLMGTFTKSFGATGGYIAGKKELVDYLRCHSHSAVYATAMSP------PVVEQIIRA 415
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Xenopus
Match: sptlc1 (serine palmitoyltransferase, long chain base subunit 1 [Source:NCBI gene;Acc:779626]) HSP 1 Score: 427.557 bits (1098), Expect = 3.861e-145 Identity = 236/461 (51.19%), Postives = 309/461 (67.03%), Query Frame = 3
Query: 129 PTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGV---AQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRL-RLNNTEER----LEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVG 1487
P YHL+ E +LI+ + L FS++YK E LT+KE+EELI +W+PEPLVP + + + S KIV K +N ASFNF L+ N+++ A +LRKYGVG+CGPRGFYGTFDVHL+LE+ +A FM EE+++YSYGF+T+ASAIPAY+KRGD++F DE FAIQ GL ASRS IKYFKHNDMD L LL+EQ E KNP KA +TR FIV EGLYMN GDICPLPK+VELKYKYKVRIFL+E+LSFGVLG+HGRGVT+HFG+++ DIDLI+ ++E ALA+ GGF G +V+DHQRLSGQGYCFSASLPPLLA A L ++ G R++ I K + +C K+ E SP H++L + E+ L+ ++ + +T ARYL++ E P PSIR+ + TDEE++ +V+++
Sbjct: 19 PAYHLILEGILILWIIRLIFSKTYKLQERSDLTEKEKEELIDEWRPEPLVPPVSKDHPALNYNIVSGPPSH--KIVV----NGKECINFASFNFLGLLDNDRVKSAALASLRKYGVGTCGPRGFYGTFDVHLELEERLAKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDEAACFAIQKGLQASRSSIKYFKHNDMDDLERLLKEQELEDQKNPRKASVTRRFIVAEGLYMNTGDICPLPKLVELKYKYKVRIFLEESLSFGVLGEHGRGVTEHFGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLASAAIEGLNIMEENSGKLFDTLRVKCKRIHKALQG-ICG-----LKVVGESFSPAFHLQLEKSTGCREKDMKLLQNIIDHCMNRKIALTLARYLEKEEKFLPTPSIRVVVTVEQTDEELDTAASVIKQAA 467
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Xenopus
Match: sptlc1 (serine palmitoyltransferase, long chain base subunit 1 [Source:NCBI gene;Acc:779626]) HSP 1 Score: 427.172 bits (1097), Expect = 4.008e-145 Identity = 237/463 (51.19%), Postives = 310/463 (66.95%), Query Frame = 3
Query: 129 PTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISS--FGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGV---AQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRL-RLNNTEER----LEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVG 1487
P YHL+ E +LI+ + L FS++YK E LT+KE+EELI +W+PEPLVP P +++S KIV K +N ASFNF L+ N+++ A +LRKYGVG+CGPRGFYGTFDVHL+LE+ +A FM EE+++YSYGF+T+ASAIPAY+KRGD++F DE FAIQ GL ASRS IKYFKHNDMD L LL+EQ E KNP KA +TR FIV EGLYMN GDICPLPK+VELKYKYKVRIFL+E+LSFGVLG+HGRGVT+HFG+++ DIDLI+ ++E ALA+ GGF G +V+DHQRLSGQGYCFSASLPPLLA A L ++ G R++ I K + +C K+ E SP H++L + E+ L+ ++ + +T ARYL++ E P PSIR+ + TDEE++ +V+++
Sbjct: 9 PAYHLILEGILILWIIRLIFSKTYKLQERSDLTEKEKEELIDEWRPEPLVP----PVSKDHPALNYNIVSGPPSHKIVV----NGKECINFASFNFLGLLDNDRVKSAALASLRKYGVGTCGPRGFYGTFDVHLELEERLAKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDEAACFAIQKGLQASRSSIKYFKHNDMDDLERLLKEQELEDQKNPRKASVTRRFIVAEGLYMNTGDICPLPKLVELKYKYKVRIFLEESLSFGVLGEHGRGVTEHFGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLASAAIEGLNIMEENSGKLFDTLRVKCKRIHKALQG-ICG-----LKVVGESFSPAFHLQLEKSTGCREKDMKLLQNIIDHCMNRKIALTLARYLEKEEKFLPTPSIRVVVTVEQTDEELDTAASVIKQAA 457
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Xenopus
Match: sptlc1 (serine palmitoyltransferase, long chain base subunit 1 [Source:NCBI gene;Acc:779626]) HSP 1 Score: 417.927 bits (1073), Expect = 1.214e-141 Identity = 228/443 (51.47%), Postives = 298/443 (67.27%), Query Frame = 3
Query: 186 FSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISS--FGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGV--AQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRL-RLNNTEER----LEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVG 1487
FS++YK E LT+KE+EELI +W+PEPLVP P +++S KIV K +N ASFNF L+ N+++ A +LRKYGVG+CGPRGFYGTFDVHL+LE+ +A FM EE+++YSYGF+T+ASAIPAY+KRGD++F DE FAIQ GL ASRS IKYFKHNDMD L LL+EQ E KNP KA +TR FIV EGLYMN GDICPLPK+VELKYKYKVRIFL+E+LSFGVLG+HGRGVT+HFG+++ DIDLI+ ++E ALA+ GGF G +V+DHQRLSGQGYCFSASLPPLLA A L ++ + R++ I K + +C K+ E SP H++L + E+ L+ ++ + +T ARYL++ E P PSIR+ + TDEE++ +V+++
Sbjct: 20 FSKTYKLQERSDLTEKEKEELIDEWRPEPLVP----PVSKDHPALNYNIVSGPPSHKIVV----NGKECINFASFNFLGLLDNDRVKSAALASLRKYGVGTCGPRGFYGTFDVHLELEERLAKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDEAACFAIQKGLQASRSSIKYFKHNDMDDLERLLKEQELEDQKNPRKASVTRRFIVAEGLYMNTGDICPLPKLVELKYKYKVRIFLEESLSFGVLGEHGRGVTEHFGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLASAAIEGLNIMEENSELFDTLRVKCKRIHKALQG-ICG-----LKVVGESFSPAFHLQLEKSTGCREKDMKLLQNIIDHCMNRKIALTLARYLEKEEKFLPTPSIRVVVTVEQTDEELDTAASVIKQAA 448
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Xenopus
Match: sptlc1 (serine palmitoyltransferase, long chain base subunit 1 [Source:NCBI gene;Acc:779626]) HSP 1 Score: 410.609 bits (1054), Expect = 7.487e-139 Identity = 228/435 (52.41%), Postives = 293/435 (67.36%), Query Frame = 3
Query: 129 PTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGV---AQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRL-RLNNTEER----LEKAVNLAYQEGLLITEARYLKESEYKCPKP 1409
P YHL+ E +LI+ + L FS++YK E LT+KE+EELI +W+PEPLVP + + + S KIV K +N ASFNF L+ N+++ A +LRKYGVG+CGPRGFYGTFDVHL+LE+ +A FM EE+++YSYGF+T+ASAIPAY+KRGD++F DE FAIQ GL ASRS IKYFKHNDMD L LL+EQ E KNP KA +TR FIV EGLYMN GDICPLPK+VELKYKYKVRIFL+E+LSFGVLG+HGRGVT+HFG+++ DIDLI+ ++E ALA+ GGF G +V+DHQRLSGQGYCFSASLPPLLA A L ++ G R++ I K + +C K+ E SP H++L + E+ L+ ++ + +T ARYL++ E P P
Sbjct: 9 PAYHLILEGILILWIIRLIFSKTYKLQERSDLTEKEKEELIDEWRPEPLVPPVSKDHPALNYNIVSGPPSH--KIVV----NGKECINFASFNFLGLLDNDRVKSAALASLRKYGVGTCGPRGFYGTFDVHLELEERLAKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDEAACFAIQKGLQASRSSIKYFKHNDMDDLERLLKEQELEDQKNPRKASVTRRFIVAEGLYMNTGDICPLPKLVELKYKYKVRIFLEESLSFGVLGEHGRGVTEHFGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLASAAIEGLNIMEENSGKLFDTLRVKCKRIHKALQG-ICG-----LKVVGESFSPAFHLQLEKSTGCREKDMKLLQNIIDHCMNRKIALTLARYLEKEEKFLPTP 431
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Xenopus
Match: sptlc1 (serine palmitoyltransferase, long chain base subunit 1 [Source:NCBI gene;Acc:779626]) HSP 1 Score: 409.068 bits (1050), Expect = 5.915e-138 Identity = 228/435 (52.41%), Postives = 293/435 (67.36%), Query Frame = 3
Query: 129 PTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGV---AQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRL-RLNNTEER----LEKAVNLAYQEGLLITEARYLKESEYKCPKP 1409
P YHL+ E +LI+ + L FS++YK E LT+KE+EELI +W+PEPLVP + + + S KIV K +N ASFNF L+ N+++ A +LRKYGVG+CGPRGFYGTFDVHL+LE+ +A FM EE+++YSYGF+T+ASAIPAY+KRGD++F DE FAIQ GL ASRS IKYFKHNDMD L LL+EQ E KNP KA +TR FIV EGLYMN GDICPLPK+VELKYKYKVRIFL+E+LSFGVLG+HGRGVT+HFG+++ DIDLI+ ++E ALA+ GGF G +V+DHQRLSGQGYCFSASLPPLLA A L ++ G R++ I K + +C K+ E SP H++L + E+ L+ ++ + +T ARYL++ E P P
Sbjct: 19 PAYHLILEGILILWIIRLIFSKTYKLQERSDLTEKEKEELIDEWRPEPLVPPVSKDHPALNYNIVSGPPSH--KIVV----NGKECINFASFNFLGLLDNDRVKSAALASLRKYGVGTCGPRGFYGTFDVHLELEERLAKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDEAACFAIQKGLQASRSSIKYFKHNDMDDLERLLKEQELEDQKNPRKASVTRRFIVAEGLYMNTGDICPLPKLVELKYKYKVRIFLEESLSFGVLGEHGRGVTEHFGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLASAAIEGLNIMEENSGKLFDTLRVKCKRIHKALQG-ICG-----LKVVGESFSPAFHLQLEKSTGCREKDMKLLQNIIDHCMNRKIALTLARYLEKEEKFLPTP 441
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Mouse
Match: Sptlc1 (serine palmitoyltransferase, long chain base subunit 1 [Source:MGI Symbol;Acc:MGI:1099431]) HSP 1 Score: 410.609 bits (1054), Expect = 1.259e-138 Identity = 230/451 (51.00%), Postives = 301/451 (66.74%), Query Frame = 3
Query: 129 PTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGV--AQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEER------LEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIE 1457
P YHL+ E +LI+ + L FS++YK E LT KE+EELI +W+PEPLVP P +++S G + K +N ASFNF L+ N ++ TA +L+KYGVG+CGPRGFYGTFDVHL LE+ +A FM EE+++YSYGFST+ASAIPAY+KRGD+IF D FAIQ GL ASRS IK FKHND+ L LL+EQ E KNP KAR+TR FIV+EGLYMN G ICPLP++V+LKYKYK RIFL+E+LSFGVLG+HGRGVT+H+G+ + DIDLI+ ++E ALA+ GGF G +VVDHQRLSGQGYCFSASLPPLLA A L ++ + + + I K + + S L K+ E +SP H++L +T R L+ V+ +G+ +T+ARYL + E P PSIR+ + T+EE++
Sbjct: 21 PAYHLILEGILILWIIRLVFSKTYKLQERSDLTAKEKEELIEEWQPEPLVP----PVSKNHPALNYNIVS--GPPTHNIVVNGKECVNFASFNFLGLLANPRVKATAFSSLKKYGVGTCGPRGFYGTFDVHLDLEERLAKFMKTEEAIIYSYGFSTIASAIPAYSKRGDIIFVDSAACFAIQKGLQASRSDIKLFKHNDVADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGISIDDIDLISANMENALASVGGFCCGRSFVVDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENPDIFAVLKKKCQNIHKSLQGV--SGL----KVVGESLSPALHLQLE-ESTGSREKDVKLLQAIVDQCMDKGIALTQARYLDKEEKCLPPPSIRVVVTVEQTEEELQ 458
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Mouse
Match: Sptlc3 (serine palmitoyltransferase, long chain base subunit 3 [Source:MGI Symbol;Acc:MGI:2444678]) HSP 1 Score: 161.77 bits (408), Expect = 8.053e-43 Identity = 116/413 (28.09%), Postives = 200/413 (48.43%), Query Frame = 3
Query: 384 VLNLASFNFFNLIGNEKINET---AQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARI-TRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEG-VAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVGENLSNP**CSFFMFN----FVIINSITFFNEMNFDNLGVE 1595
++N+AS+N+ L G K +++ + L KYGVG R GT D+H +LED +A F+N E + + GF+T A IP + +G +I +DE ++ G S + I+ FKHN+ ++L LL E P R + IV+EG+Y G I L +IV LK KYK +++DE S G G GRGV + FG+D DID+ G+ + + GG+ G K +VD+ R+ ++ S+ P++A L++ EG + R+ ++ + I M + + D SP+ + L + ++ ++ + + + S P+ R S++ A T E ++ V++ +G+ L+ +F ++ N F NE +F+ + E
Sbjct: 162 IINMASYNYLGLAG--KYDDSMVRVKDTLEKYGVGVASTRNEMGTLDIHKELEDLMAEFLNVEAVMSFGMGFATNAMNIPVFVGKGCLILSDEFNHTSVILGSRLSGAVIRPFKHNNAENLEKLLREAIIRG--QPGTGRAWKKILIVVEGVYSMEGSIVNLAQIVALKKKYKAYLYIDEAHSIGCTGPTGRGVRELFGLDPEDIDVYMGTFTKSFSGSGGYIGGKKEIVDYLRMQSHSTTYATSMSPVVAAQLIRSLKITMGYEGNIGGMERIQQLKENIKYFRRRLKEMGFIIYGNDFSPVIPVLLYM---PAKVSAFSRFLLKKKISVVVVGFPATS---LPEGRARFSMSSAHTREMLDTVLEVVDELGDLLN----VKYFPLKKSGRAILYNKEGFDNEASFEEMHSE 560
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Mouse
Match: Sptlc3 (serine palmitoyltransferase, long chain base subunit 3 [Source:MGI Symbol;Acc:MGI:2444678]) HSP 1 Score: 161.77 bits (408), Expect = 8.053e-43 Identity = 116/413 (28.09%), Postives = 200/413 (48.43%), Query Frame = 3
Query: 384 VLNLASFNFFNLIGNEKINET---AQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARI-TRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEG-VAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVGENLSNP**CSFFMFN----FVIINSITFFNEMNFDNLGVE 1595
++N+AS+N+ L G K +++ + L KYGVG R GT D+H +LED +A F+N E + + GF+T A IP + +G +I +DE ++ G S + I+ FKHN+ ++L LL E P R + IV+EG+Y G I L +IV LK KYK +++DE S G G GRGV + FG+D DID+ G+ + + GG+ G K +VD+ R+ ++ S+ P++A L++ EG + R+ ++ + I M + + D SP+ + L + ++ ++ + + + S P+ R S++ A T E ++ V++ +G+ L+ +F ++ N F NE +F+ + E
Sbjct: 162 IINMASYNYLGLAG--KYDDSMVRVKDTLEKYGVGVASTRNEMGTLDIHKELEDLMAEFLNVEAVMSFGMGFATNAMNIPVFVGKGCLILSDEFNHTSVILGSRLSGAVIRPFKHNNAENLEKLLREAIIRG--QPGTGRAWKKILIVVEGVYSMEGSIVNLAQIVALKKKYKAYLYIDEAHSIGCTGPTGRGVRELFGLDPEDIDVYMGTFTKSFSGSGGYIGGKKEIVDYLRMQSHSTTYATSMSPVVAAQLIRSLKITMGYEGNIGGMERIQQLKENIKYFRRRLKEMGFIIYGNDFSPVIPVLLYM---PAKVSAFSRFLLKKKISVVVVGFPATS---LPEGRARFSMSSAHTREMLDTVLEVVDELGDLLN----VKYFPLKKSGRAILYNKEGFDNEASFEEMHSE 560
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Mouse
Match: Sptlc2 (serine palmitoyltransferase, long chain base subunit 2 [Source:MGI Symbol;Acc:MGI:108074]) HSP 1 Score: 160.229 bits (404), Expect = 2.632e-42 Identity = 88/276 (31.88%), Postives = 144/276 (52.17%), Query Frame = 3
Query: 360 FNENKTKPVLNLASFNFFNLIGNE-KINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQ---SEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVA 1175
+ N K V+N+ S+N+ N E A + L++YG G C R G D H +LE +A F+ E ++ Y GF+T + IPA +G +I +DE ++ G S + I+ FKHN+M L LL++ + + P K + I++EG+Y G I LP+++ LK KYK ++LDE S G LG GRGV D+FG+D D+D++ G+ + GG+ G K ++D+ R ++ S+ P + ++ I ++G +
Sbjct: 160 YTGNIIKGVINMGSYNYLGFARNTGSCQEAAAEVLKEYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAAMTYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWK----KILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIMGQDGTS 431
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Mouse
Match: Alas2 (aminolevulinic acid synthase 2, erythroid [Source:MGI Symbol;Acc:MGI:87990]) HSP 1 Score: 122.479 bits (306), Expect = 4.251e-29 Identity = 79/288 (27.43%), Postives = 144/288 (50.00%), Query Frame = 3
Query: 375 TKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAK--RGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSR 1232
+K V S ++ + + ++ + ++ L+ +G G+ G R GT H++LE E+A + ++++S F S + AK G I++D G ++ G+ S + F+HND HL LLE+ +P +I + E ++ G ICPL ++ ++ ++Y F+DE + G+ G G G+ + G+ + +D+I+G+L A GG+ ++ +VD R G+ F+ SLPP++ GA + +++ EEG A R K + LL R
Sbjct: 188 SKDVSVWCSNDYLGISRHPRVLQAIEETLKNHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKLLPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPGHLKKLLEK------SDPKTPKI----VAFETVHSMDGAICPLEELCDVAHQYGALTFVDEVHAVGLYGARGAGIGERDGI-MHKLDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDR 464
BLAST of Serine palmitoyltransferase 1 vs. UniProt/SwissProt
Match: sp|P91079|SPTC1_CAEEL (Serine palmitoyltransferase 1 OS=Caenorhabditis elegans OX=6239 GN=sptl-1 PE=3 SV=1) HSP 1 Score: 415.616 bits (1067), Expect = 5.126e-140 Identity = 212/406 (52.22%), Postives = 278/406 (68.47%), Query Frame = 3
Query: 252 ADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIR---LNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEG-LLITEARYLKESEYKCPKPSIRLSINCALTDEEIE 1457
ADW PEPLVP+ Q + ++ K+ GK+ + LN+AS NF + IG ++I + A++ + KYGVGSCGPRGFYGT DVHL LE E+A FM CEE+V+YSYGF+TV+SAIPAYAK+GDVIF DEGV+FAIQ GL ASRS+++YFKHNDM+HL LL EQ + K+P KA+ R FIV+EGLY+NY D+CPLPKI+E K+++KVR+F+DE+ SFGV+G GRGVT+HF V + D+D++ SLE ALA+ GGF VG YVV HQRLSG GYCFSASLPPLLA AS + +I E Q++ +N K +L S+ S L SP+KHI + E++L+ V + + LL+T ARYL + E +PSIR+ LT+EEI+
Sbjct: 50 ADWTPEPLVPETPQDHPVLNPKYAD------GKMTKDVSIDGEKYLNMASTNFLSFIGVKRIEDRAKQTIFKYGVGSCGPRGFYGTVDVHLDLEKELAKFMGCEEAVLYSYGFATVSSAIPAYAKKGDVIFVDEGVNFAIQKGLQASRSRVEYFKHNDMEHLERLLLEQEQRDKKDPKKAKSVRRFIVVEGLYVNYADLCPLPKIIEFKWRFKVRVFIDESWSFGVIGKTGRGVTEHFNVPMEDVDMVMASLENALASTGGFCVGRSYVVGHQRLSGLGYCFSASLPPLLATAASEAISIIDEEPSRVQKVTEMAINGQKKLQDALSGSKFS----LQGCPESPMKHIYYNGEDEEKQLDTFVETVFTKNHLLLTRARYLDKDELFKIRPSIRVMFQHDLTEEEIQ 445
BLAST of Serine palmitoyltransferase 1 vs. UniProt/SwissProt
Match: sp|O54695|SPTC1_CRIGR (Serine palmitoyltransferase 1 OS=Cricetulus griseus OX=10029 GN=SPTLC1 PE=1 SV=1) HSP 1 Score: 412.92 bits (1060), Expect = 1.063e-138 Identity = 230/451 (51.00%), Postives = 301/451 (66.74%), Query Frame = 3
Query: 129 PTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGV--AQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEER------LEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIE 1457
P YHL+ E +LI+ + L FS++YK E LT KE+EELI +W+PEPLVP P +++S G + K +N ASFNF L+ N ++ A +L+KYGVG+CGPRGFYGTFDVHL LE+ +A FM EE+++YSYGFST+ASAIPAY+KRGD++F D FAIQ GL ASRS IK FKHND+ L LL+EQ E KNP KAR+TR FIV+EGLYMN G +CPLP++V+LKYKYK RIFL+E+LSFGVLG+HGRGVT+H+G+ + DIDLI+ ++E ALA+ GGF G +VVDHQRLSGQGYCFSASLPPLLA A L ++ G+ + + I K + + S L K+ E +SP H++L +T R L++ V EG+ +T+ARYL + E P PSIR+ + T+EE+E
Sbjct: 21 PAYHLILEGILILWIIRLVFSKTYKLQERSDLTAKEKEELIEEWQPEPLVP----PVSKNHPALNYNIVS--GPPTHNIVVNGKECVNFASFNFLGLLANPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEERLAKFMRTEEAIIYSYGFSTIASAIPAYSKRGDIVFVDSAACFAIQKGLQASRSDIKLFKHNDVADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTVCPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGISIDDIDLISANMENALASVGGFCCGRSFVVDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENPGIFAVLKKKCQHIHKSLQGI--SGL----KVVGESLSPALHLQLE-ESTGSREKDVQLLQEMVIHCMNEGIALTQARYLDKEEKCLPPPSIRVVVTVEQTEEELE 458
BLAST of Serine palmitoyltransferase 1 vs. UniProt/SwissProt
Match: sp|O35704|SPTC1_MOUSE (Serine palmitoyltransferase 1 OS=Mus musculus OX=10090 GN=Sptlc1 PE=1 SV=2) HSP 1 Score: 410.609 bits (1054), Expect = 8.809e-138 Identity = 230/451 (51.00%), Postives = 301/451 (66.74%), Query Frame = 3
Query: 129 PTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGV--AQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEER------LEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIE 1457
P YHL+ E +LI+ + L FS++YK E LT KE+EELI +W+PEPLVP P +++S G + K +N ASFNF L+ N ++ TA +L+KYGVG+CGPRGFYGTFDVHL LE+ +A FM EE+++YSYGFST+ASAIPAY+KRGD+IF D FAIQ GL ASRS IK FKHND+ L LL+EQ E KNP KAR+TR FIV+EGLYMN G ICPLP++V+LKYKYK RIFL+E+LSFGVLG+HGRGVT+H+G+ + DIDLI+ ++E ALA+ GGF G +VVDHQRLSGQGYCFSASLPPLLA A L ++ + + + I K + + S L K+ E +SP H++L +T R L+ V+ +G+ +T+ARYL + E P PSIR+ + T+EE++
Sbjct: 21 PAYHLILEGILILWIIRLVFSKTYKLQERSDLTAKEKEELIEEWQPEPLVP----PVSKNHPALNYNIVS--GPPTHNIVVNGKECVNFASFNFLGLLANPRVKATAFSSLKKYGVGTCGPRGFYGTFDVHLDLEERLAKFMKTEEAIIYSYGFSTIASAIPAYSKRGDIIFVDSAACFAIQKGLQASRSDIKLFKHNDVADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGISIDDIDLISANMENALASVGGFCCGRSFVVDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENPDIFAVLKKKCQNIHKSLQGV--SGL----KVVGESLSPALHLQLE-ESTGSREKDVKLLQAIVDQCMDKGIALTQARYLDKEEKCLPPPSIRVVVTVEQTEEELQ 458
BLAST of Serine palmitoyltransferase 1 vs. UniProt/SwissProt
Match: sp|D4A2H2|SPTC1_RAT (Serine palmitoyltransferase 1 OS=Rattus norvegicus OX=10116 GN=Sptlc1 PE=1 SV=1) HSP 1 Score: 410.223 bits (1053), Expect = 1.260e-137 Identity = 228/449 (50.78%), Postives = 298/449 (66.37%), Query Frame = 3
Query: 129 PTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMY-WKLDSEDISPIKHIRLRLNN-TEER----LEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIE 1457
P YHL+ E +LI+ + L FS++YK E LT KE+EELI +W+PEPLVP P +++S G + K +N ASFNF L+ N ++ A +L+KYGVG+CGPRGFYGTFDVHL LE+ +A FM EE+++YSYGFST+ASAIPAY+KRGD++F D FAIQ GL ASRS IK FKHND+ L LL+EQ E KNP KAR+TR FIV EGLYMN G ICPLP++V LKYKYK RIFL+E+LSFGVLG+HGRGVT+H+G+ + DIDLI+ ++E ALA+ GGF G +VVDHQRLSGQGYCFSASLPPLLA A L ++ G+ + KK ++ S + K+ E + P H++L + + ER L++ V +G+ +T+ARYL + E P PSIR+ + TDEE++
Sbjct: 21 PAYHLILEGILILWIIRLVFSKTYKLQERSDLTAKEKEELIEEWQPEPLVP----PVSRNHPALNYNIVS--GPPTHNIVVNGKECVNFASFNFLGLLANPRVKAAAFASLKKYGVGTCGPRGFYGTFDVHLDLEERLAKFMKTEEAIIYSYGFSTIASAIPAYSKRGDIVFVDSAACFAIQKGLQASRSDIKLFKHNDVADLERLLKEQEIEDQKNPRKARVTRRFIVAEGLYMNTGTICPLPELVRLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGISIDDIDLISANMENALASVGGFCCGRSFVVDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENPGI-----FAVLKKKCQTIHKSLQGVSGLKVVGESLCPALHLQLEESTGSRERDMKLLQEIVEQCMNKGIALTQARYLDKEEKCLPPPSIRVVVTVEQTDEELQ 458
BLAST of Serine palmitoyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q3MHG1|SPTC1_BOVIN (Serine palmitoyltransferase 1 OS=Bos taurus OX=9913 GN=SPTLC1 PE=2 SV=1) HSP 1 Score: 408.683 bits (1049), Expect = 4.833e-137 Identity = 230/461 (49.89%), Postives = 305/461 (66.16%), Query Frame = 3
Query: 129 PTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRL-RLNNTEER----LEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVGENL 1496
P YHL+ E +LI+ + L FS++YK E LT KE+EELI +W+PEPLVP P +++S G + K +N ASFNF L+ N ++ A +L+KYGVG+CGPRGFYGTFDVHL LED +A FM EE+++YSYGF+T+ASAIPAY+KRGD++F D+ FAIQ GL ASRS IK F HNDMD L LL+EQ E KNP KAR+TR FI++EGLYMN G +CPLP++V+LKYKYK RIFL+E+LSFGVLG+HGRGVT+HFG+ + DIDLI+ ++E +LA+ GGF G +V+DHQRLSGQGYCFSASLPPLLA A L ++ G+ L E K+I L + K+ E ISP H++L ER L++ V G+ +T+ARYL++ E P PSIR+ + T+E++E + + V + +
Sbjct: 21 PAYHLILEGILILWIIRLLFSKTYKLQERSDLTLKEKEELIEEWQPEPLVP----PVSKDHPALNYNIVS--GPPSHNIVVNGKECINFASFNFLGLLDNPRLKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDKAACFAIQKGLQASRSDIKVFNHNDMDDLERLLKEQEIEDQKNPRKARVTRRFIIVEGLYMNTGTVCPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHFGISIDDIDLISANMENSLASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENPGIFA--VLKEKCKRIHKALQGIPGL--KVVGESISPALHLQLEETTGCRERDVKLLQEIVTQCMDRGIALTQARYLEKEEKYLPPPSIRVVVTVEQTEEDLEKAASTISEVAQTV 471
BLAST of Serine palmitoyltransferase 1 vs. TrEMBL
Match: A0A0R3UHM8 (Aminotran_1_2 domain-containing protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS6859 PE=4 SV=1) HSP 1 Score: 496.123 bits (1276), Expect = 2.832e-168 Identity = 257/497 (51.71%), Postives = 339/497 (68.21%), Query Frame = 3
Query: 84 ENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNEN-------KTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSR-LSMYWKLD--SEDISPIKHIRLRL-NNTEERLEKAVNLA--------------YQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVGENLS 1499
E +W LI S + P YH FEI LII ++L F RSY + +L+ E+++LI +W PEPLVP W P K + +F ++ + + K V F + KT P LN+AS NF + IG+E +N+ A KALRKYG+G+CGPRGFYGTFD HL LE + F+ EE +YS+GFST+ASAIPAYAKR D+IFADEGVS A+ GLLASRS I+YF+HNDMDHL LL Q E + +P +A R F V+EGLY++YGDICPLP++V+LKYKYKVRI LDET+SFGVLG+ GRGVT+HFG++V +D+ITGSLETA+ GGF GS +VVDHQRLSGQGYCFSASLPP+LA + +E ++ E G QR RL I+ + L + L+ YW LD + SP+KHIRL + NT +RLE+A +LA +L+T AR+++ + K P PSIRLS+N ++TD+E+ C+V+ +VGE +S
Sbjct: 14 EYTWPRLIYSAVR-APAYHFYFEISLIIGIIWLLFKRSYNIRDNAELSSSEKKQLIEEWVPEPLVPASWTPPKKLLERFHRASVGAVKKYVQFEDRSSGKDKLKTVPHLNVASLNFLDFIGDETLNQVAIKALRKYGLGACGPRGFYGTFDAHLSLEKALETFIGVEEVALYSFGFSTIASAIPAYAKRTDIIFADEGVSQAVHEGLLASRSTIRYFRHNDMDHLEELLAAQQVEDVIDPKRASQIRRFFVVEGLYLDYGDICPLPRLVDLKYKYKVRIILDETISFGVLGEAGRGVTEHFGINVDHVDVITGSLETAIGVFGGFCAGSHFVVDHQRLSGQGYCFSASLPPILAVASEAAVECLQKESGSRQR-RLRHIAHLLQDRLQEKTLAQYWTLDPATHPDSPVKHIRLAVGKNTIDRLEEACDLASSLPQSLEVSDKALLTTPVLLTVARHVEGAHRKIPAPSIRLSLNYSITDDELMHICSVLVKVGEVIS 508
BLAST of Serine palmitoyltransferase 1 vs. TrEMBL
Match: A0A0R3T219 (Aminotran_1_2 domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS953 PE=4 SV=1) HSP 1 Score: 495.352 bits (1274), Expect = 3.896e-168 Identity = 257/491 (52.34%), Postives = 347/491 (70.67%), Query Frame = 3
Query: 84 ENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYF---NENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKI-SSLLCSRLSMYWKLD--SEDISPIKHIRLRLN-NTEERLEKAVNLAYQ------EG------LLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVGENLS 1499
E +W LI S + P YH FEIVLII ++L F RSY E L+++E+E+L+ +W PEPLVP QP+K + +F ++ + K V F + TKP LN+AS NF + IG++KIN+ A ALRKYG+GSCGPRGFYGTFD HL +E + +F+ EE +YSYGFST+ASAIPAYAKR D+IFADEGVS A++ GL ASRS I++F+HND+DHL L+ Q E + +P KA R F+V+EGLY++YGDICPLP++V+LKYKYKVRI +DE++SFGVLG GRGVT+HFG+ V ID+ITGSLE A+ CGGF GS +VVDHQRLSGQGYCFSASLPP+LA GA V +E + E+GV Q RL +++ ++ S+L ++ W LD ++ SP+ HIRL + N+ +RLE+A +LA Q EG +L+T AR+ + E K PKPSIRL++N L++EE++ V+++VGE ++
Sbjct: 14 EYTWPRLIYSAVRV-PAYHFYFEIVLIIGIIWLLFKRSYNIHEKTTLSEEEKEDLLKEWVPEPLVPASKQPSKKLLERFSRAAVGPIKKYVQFQGEDGKGTKPFLNVASLNFLDFIGDDKINKVAIAALRKYGLGSCGPRGFYGTFDAHLDMEKVLESFLGVEEVALYSYGFSTIASAIPAYAKRTDLIFADEGVSQAVKEGLTASRSTIRFFRHNDIDHLEELMRAQEAEDVLDPLKAGQIRRFLVVEGLYLDYGDICPLPQLVDLKYKYKVRIIMDESISFGVLGKEGRGVTEHFGIGVEHIDVITGSLENAIGVCGGFCAGSHFVVDHQRLSGQGYCFSASLPPMLAAGAQVAIETLATEKGVRQ-ARLRDLAHRLFSALNTPDIATVWSLDHHAQPDSPVMHIRLAIGENSIDRLEEACDLAAQLPMKEPEGGLKATPVLLTVARHSLQMERKLPKPSIRLALNYTLSNEELDHVVEVLQKVGEVMA 502
BLAST of Serine palmitoyltransferase 1 vs. TrEMBL
Match: A0A068WZS8 (Serine palmitoyltransferase long chain base OS=Echinococcus granulosus OX=6210 GN=EgrG_000146100 PE=4 SV=1) HSP 1 Score: 487.263 bits (1253), Expect = 7.079e-165 Identity = 258/495 (52.12%), Postives = 340/495 (68.69%), Query Frame = 3
Query: 84 ENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNEN---KTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLC-SRLSMYWKLD--SEDISPIKHIRLRLN-NTEERLEKAVNLAY---------------QEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVGENLSN 1502
E +W LI S + P YHL FEI LII ++L F RSY + +KL+ E+EELI +W PEPLVP W P K + +F ++ + GK V F T P LN+AS NF + IG+EK+N+ A +ALR YG+G+CGPRGFYGTFD HL LE I +F+ EE V+YSY FST+ASAIPAYAKR D+IFADEGVS AIQ GL ASRS I+YF+HND++HL LL Q E + ++A TR F+V+EGLY++YGDICPLP++V+LKYKYKVRI LDE++SFGVLG GRGVT+HFG++V +D+IT SLETA+ CGGF GS +VVDHQRLSGQGYCFSASLPP+LA A +E + E+GV Q +L ++S ++ + L + L+ +W LD S SP+KHIRL + N+ ERLE A +LA +L+T AR+ + K P+PSIRL++NC++T E++ C V+ +VGE ++
Sbjct: 14 EYTWPRLIYSALRV-PAYHLYFEICLIIGIIWLLFKRSYNIHDKVKLSAAEKEELIKEWVPEPLVPASWTPPKKLLERFHRASVGPIGKYVQFEGELGEVTPPHLNVASLNFLDFIGDEKLNKVAIEALRTYGLGACGPRGFYGTFDAHLTLEKAIESFLGVEEVVLYSYAFSTIASAIPAYAKRTDLIFADEGVSQAIQEGLRASRSAIRYFRHNDINHLEELLLAQEAEDSNDLSRASHTRRFLVVEGLYLDYGDICPLPQLVDLKYKYKVRIILDESISFGVLGKAGRGVTEHFGINVEHVDIITSSLETAIGMCGGFCAGSHFVVDHQRLSGQGYCFSASLPPMLAAAAQAAVEQLGVEDGVRQS-QLRDLSHRLQAALAEAPLAQFWSLDFHSNPDSPVKHIRLAVGANSMERLEHACDLAAALPRADASELKKELEATPVLLTVARHTSNTLRKIPEPSIRLALNCSMTTAELDHVCEVLRKVGETMAG 506
BLAST of Serine palmitoyltransferase 1 vs. TrEMBL
Match: A0A0R3X6J2 (Aminotran_1_2 domain-containing protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS9113 PE=4 SV=1) HSP 1 Score: 481.871 bits (1239), Expect = 1.012e-162 Identity = 254/497 (51.11%), Postives = 342/497 (68.81%), Query Frame = 3
Query: 84 ENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENK----TKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKI-SSLLCSRLSMYWKLD--SEDISPIKHIRLRLN-NTEERLEKAVNLAY----------------QEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVGENLSN 1502
E +W LI S + P YHL FEI LII ++L F RSY + KL+ E+E+LI +W PEPLVP W P+K + +F ++ + S GK V F E K T LN+AS NF + IG++K+N+ A KALR YG+G+CGPRGFYGTFD HL LE I +F+ EE +YSY FST+ASAIPAYAKR DVIFADEGV A++ GL ASRS ++YF+HND++HL L+ Q E NP +A R F+V+EGLY++YGDICPLP +V+LKYKYKVRI LDE++SFGVLG GRGVT+HFG++V +DLIT SLETA+ CGGF GS +VVDHQRLSGQGYCFSASLPP+LA A +E + +E+GV Q +L +S ++ ++L+ + L+ +W L+ S SP+KHIRL + N+ ERLE A +LA +L+T AR+ + + K P+PSIRL++NC++T E++ C ++++VGE ++
Sbjct: 14 EYTWPRLIYSAVRV-PAYHLYFEICLIIGIIWLLFKRSYNIHDKAKLSAAEKEDLIREWIPEPLVPTSWVPSKKLLERFHRASVGSIGKYVRF-EGKGGEVTPSHLNVASLNFLDFIGDDKLNKVAIKALRTYGLGACGPRGFYGTFDAHLTLEKAIESFLGVEEVALYSYAFSTIASAIPAYAKRTDVIFADEGVGQAVREGLRASRSTVRYFRHNDINHLEELMVAQEAEDSDNPYRASQIRRFLVVEGLYLDYGDICPLPHLVDLKYKYKVRIILDESISFGVLGKTGRGVTEHFGINVEHVDLITSSLETAIGVCGGFCAGSHFVVDHQRLSGQGYCFSASLPPMLAAAAQAAVEQLTSEDGVRQS-QLRRLSHRLQAALMEAALAQFWSLEPCSHPDSPVKHIRLAVGANSMERLEYACDLASTLSSVDASESRKEELGTTPVLLTVARHAENTLRKVPEPSIRLALNCSMTTAELDHVCKMLQKVGEIMAG 507
BLAST of Serine palmitoyltransferase 1 vs. TrEMBL
Match: A0A0R3STH5 (Aminotran_1_2 domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS8707 PE=4 SV=1) HSP 1 Score: 481.1 bits (1237), Expect = 2.010e-162 Identity = 251/492 (51.02%), Postives = 346/492 (70.33%), Query Frame = 3
Query: 84 ENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYF---NENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKI-SSLLCSRLSMYWKLD--SEDISPIKHIRLRLN-NTEERLEKAVNLAYQ-------EGL-----LITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVGENLSN 1502
E +W LI S + P YH FEI LI+ ++L F RSY + +KL++KE+E+L+ +W PEPLVP WQP+K +F ++ + K V F + + + P LN+AS NF + IG+ +N+ A +ALRKYG+G+CGPRGFYGTFD HL LE + +F+ EE +YSYGFST+ASAIPAYAKR D+IFAD+GVS A++ GL+ASRS I++F+HND+DHL L+ Q E + +P++A R F+V+EGLY++YGDICPLP++V+LKYKYKVRI +DE++SFGVLG GRGVT++FG+ V +D+ITGSLE A+ CGGF GS +VVDHQRLSGQGYCFSASLPP+LA GA V +E + AE GV Q RL E+S ++ S+L + W LD ++ SP+ HIRL + N+ +RLE+A +LA Q +GL L+T AR+ S K P PSIRL++N +++EE++ V++RVGE ++
Sbjct: 14 EYTWPRLIYSAVRV-PAYHFYFEIFLILGIIWLLFKRSYNIHDKVKLSEKEKEDLLKEWVPEPLVPASWQPSKKCLERFSRAAVGPIKKYVQFQGKDGHASSPFLNVASLNFLDFIGDGNLNKVAIEALRKYGLGACGPRGFYGTFDAHLDLERVLESFLGVEEVALYSYGFSTIASAIPAYAKRTDLIFADDGVSQAVREGLIASRSTIRFFRHNDIDHLEELMRGQEAEDLLDPSRASQIRRFLVVEGLYLDYGDICPLPQLVDLKYKYKVRIIMDESISFGVLGKAGRGVTEYFGIGVEHVDVITGSLENAIGVCGGFCAGSHFVVDHQRLSGQGYCFSASLPPMLAAGAQVAIETLAAENGVRQ-ARLRELSHRLFSALNKPDIGAIWCLDHHAQPDSPVMHIRLAVGENSIDRLEEACDLAAQLPTKEQGDGLKVTPVLLTVARHALFSGRKLPNPSIRLALNYTMSNEELDHVVEVLQRVGEVMAK 503
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Cavefish
Match: sptlc1 (serine palmitoyltransferase, long chain base subunit 1 [Source:ZFIN;Acc:ZDB-GENE-050522-61]) HSP 1 Score: 415.231 bits (1066), Expect = 1.976e-140 Identity = 232/459 (50.54%), Postives = 309/459 (67.32%), Query Frame = 3
Query: 99 ELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEER------LEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIE 1457
E++ +F P YHL+ E +LI+ + L FS++YK E LT+KE+EELI +W+PEPLVP +K S+ V + N K +N SFNF L+ NE++ + A +LRKYGVG+CGPRGFYGTFDVHL+LE+ +A FM EE+++YSYGF+T+ASAIPAY+KRGD++F DE F+IQ GL ASRS IKYFKHNDM+ L LL+EQ E KNP KAR+TR FIV+EGLYMN DICPLP++V+LKYKYKVRIFL+E++SFGVLG+HGRGVT+HFGV++ DIDLI+ ++E A+A+ GGF G +V+DHQRLSGQGYCFSASLPP+LA A L ++ + + +R E K + L + K+ E +P H++L N+T R L ++ + +T+ARYL + E P PSIR+ T+EEIE
Sbjct: 23 EMVQAFYE-APAYHLILEGILILWIIRLLFSKTYKLQERSDLTEKEKEELIEEWQPEPLVPP---VSKDHPSQNYDVVTGPPSHKIIVN---GKECINFGSFNFLGLLDNERVKQKALASLRKYGVGTCGPRGFYGTFDVHLELEERLAKFMRTEEAIIYSYGFATIASAIPAYSKRGDIVFVDEASCFSIQKGLQASRSFIKYFKHNDMEDLERLLKEQELEDQKNPRKARVTRRFIVVEGLYMNTADICPLPELVKLKYKYKVRIFLEESMSFGVLGEHGRGVTEHFGVNIDDIDLISANMENAVASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPMLASAAIEALNIMEEDPEIFTVLR--EKCKHVHKTLQGIPGL--KVVGEAFAPALHLQLE-NSTGSRESDVRTLRSIIDYCLDRQIALTQARYLDKEERFLPPPSIRVVATVEQTEEEIE 469
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Cavefish
Match: sptlc2a (serine palmitoyltransferase, long chain base subunit 2a [Source:ZFIN;Acc:ZDB-GENE-050522-23]) HSP 1 Score: 154.451 bits (389), Expect = 5.787e-40 Identity = 89/281 (31.67%), Postives = 145/281 (51.60%), Query Frame = 3
Query: 378 KPVLNLASFNFFNLIGNE-KINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEE---QSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVA-QRIRLNEISK 1205
K V+N+ S+N+ N E A + KYGVG R G D H ++E +A F+ E ++ + GF+T + IPA +G +I +DE ++ G S S I+ FKHN+M L LL + + P K + I++EG+Y G I LP+++ LK KYK ++LDE S G LG GRGV ++FG+D TD+D++ G+ + GG+ G K ++D+ R ++ S+ P + ++ I E+G R R+ ++++
Sbjct: 239 KDVINMGSYNYLGFAENTGSCAEAAAEVTVKYGVGVSSTRQEMGNLDRHEEMEKLVARFLGVESAMAFGMGFATNSMNIPALTGKGCLILSDELNHASLVLGARLSGSTIRVFKHNNMQSLEKLLRDAIVHGQPRTHRPWK----KILILVEGIYSMEGSIIRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVEYFGLDPTDVDIMMGTFTKSFGAAGGYIGGKKELIDYLRSHSHSAVYATSMSPPVVEQIITSMKCIMGEDGTTIGRERVQQLAE 515
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Cavefish
Match: sptlc2a (serine palmitoyltransferase, long chain base subunit 2a [Source:ZFIN;Acc:ZDB-GENE-050522-23]) HSP 1 Score: 154.451 bits (389), Expect = 6.237e-40 Identity = 89/281 (31.67%), Postives = 145/281 (51.60%), Query Frame = 3
Query: 378 KPVLNLASFNFFNLIGNE-KINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEE---QSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVA-QRIRLNEISK 1205
K V+N+ S+N+ N E A + KYGVG R G D H ++E +A F+ E ++ + GF+T + IPA +G +I +DE ++ G S S I+ FKHN+M L LL + + P K + I++EG+Y G I LP+++ LK KYK ++LDE S G LG GRGV ++FG+D TD+D++ G+ + GG+ G K ++D+ R ++ S+ P + ++ I E+G R R+ ++++
Sbjct: 260 KDVINMGSYNYLGFAENTGSCAEAAAEVTVKYGVGVSSTRQEMGNLDRHEEMEKLVARFLGVESAMAFGMGFATNSMNIPALTGKGCLILSDELNHASLVLGARLSGSTIRVFKHNNMQSLEKLLRDAIVHGQPRTHRPWK----KILILVEGIYSMEGSIIRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVEYFGLDPTDVDIMMGTFTKSFGAAGGYIGGKKELIDYLRSHSHSAVYATSMSPPVVEQIITSMKCIMGEDGTTIGRERVQQLAE 536
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Cavefish
Match: sptlc2a (serine palmitoyltransferase, long chain base subunit 2a [Source:ZFIN;Acc:ZDB-GENE-050522-23]) HSP 1 Score: 154.451 bits (389), Expect = 6.237e-40 Identity = 89/281 (31.67%), Postives = 145/281 (51.60%), Query Frame = 3
Query: 378 KPVLNLASFNFFNLIGNE-KINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEE---QSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVA-QRIRLNEISK 1205
K V+N+ S+N+ N E A + KYGVG R G D H ++E +A F+ E ++ + GF+T + IPA +G +I +DE ++ G S S I+ FKHN+M L LL + + P K + I++EG+Y G I LP+++ LK KYK ++LDE S G LG GRGV ++FG+D TD+D++ G+ + GG+ G K ++D+ R ++ S+ P + ++ I E+G R R+ ++++
Sbjct: 260 KDVINMGSYNYLGFAENTGSCAEAAAEVTVKYGVGVSSTRQEMGNLDRHEEMEKLVARFLGVESAMAFGMGFATNSMNIPALTGKGCLILSDELNHASLVLGARLSGSTIRVFKHNNMQSLEKLLRDAIVHGQPRTHRPWK----KILILVEGIYSMEGSIIRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVEYFGLDPTDVDIMMGTFTKSFGAAGGYIGGKKELIDYLRSHSHSAVYATSMSPPVVEQIITSMKCIMGEDGTTIGRERVQQLAE 536
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Cavefish
Match: gcat (glycine C-acetyltransferase [Source:NCBI gene;Acc:103043864]) HSP 1 Score: 114.005 bits (284), Expect = 6.347e-27 Identity = 85/304 (27.96%), Postives = 148/304 (48.68%), Query Frame = 3
Query: 276 VPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGS-LETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRI 1184
V W+ ++I SK + + IS G + +LN + N+ L + ++ + +AL+KYG G R GT D+H KLE ++A F E+ ++Y+ F A D + +DE +I G+ R+K +KH D++ L E+ +K +R+ +V +G++ GD+ PL I +L +Y +F+DE + G LG GRG + GV + + ++ + + GG++VG K ++D R + Y FS SLPP + A+ +E++ A +AQ +
Sbjct: 51 VAGTWKGERVITSK-QGAHISVDGS--------SADILNFCANNYLGLSSHPEVIQAGIEALQKYGAGLSSVRFICGTQDLHKKLEQKLAQFHEREDCILYASCFDANAGLFEVLLGPEDAVLSDELNHASIIDGIRLCRAKRLRYKHMDLNDL--------EDKLKESQSSRL--RLVVTDGVFSMDGDVAPLVGICDLAEQYGALVFIDECHATGFLGIRGRGTDELLGV-MDRVHIVNSTLGKALGGAAGGYTVGPKPLIDLLRQRSRPYLFSNSLPPPVVGSATRAVELLLASNEIAQSM 334
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Sea Lamprey
Match: sptlc1 (serine palmitoyltransferase, long chain base subunit 1 [Source:ZFIN;Acc:ZDB-GENE-050522-61]) HSP 1 Score: 388.267 bits (996), Expect = 1.145e-130 Identity = 219/438 (50.00%), Postives = 302/438 (68.95%), Query Frame = 3
Query: 177 FLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRL----RLNNTEER-LEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVM 1475
L+FS+SY+ LE LT KE+EELI +W P+PLVP Q + + V GK + N+ K +NLASFNF L+ N+++ + A ++L KYGVG+CGPRGFYGTFDVHL+LE++IA FM CEE+++Y+YGFST+ASAIPAY+KRGD+I+ + V FAIQ GL ASRS +KYF+HND+ L LL++Q +E KNP KA + R F+V+EGLY N GD+CPLP +V LKY+YKVRIFL+E+LSFGVLG+ GRGVT+HFGV++ DIDLI+ ++E ALA+ GGF G +V+DHQRLSGQGYCFSASLPPLLA A L ++ + +R + SK + L + L E +SP H+RL R + + R L++ L ++G+ +T+A+YL++ E PS+R+ ++ LT EE++ V+
Sbjct: 38 LLFFSKSYRVLERSDLTDKEKEELIEEWTPDPLVPPVPQDHPALHYSI---VSGEPGKKIVVND---KECINLASFNFLGLLSNKRVKKVALESLAKYGVGTCGPRGFYGTFDVHLELEEQIARFMRCEEAIIYAYGFSTIASAIPAYSKRGDIIYVSKAVCFAIQKGLQASRSNVKYFRHNDVADLERLLQQQQQEDRKNPKKASVVRRFLVVEGLYTNTGDVCPLPDLVRLKYQYKVRIFLEESLSFGVLGETGRGVTEHFGVNIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLAAAAMEALSIVEECPDIFGELR--KRSKHMHRALQDVPGLL--LCGESLSPAVHLRLAEPSRSRDKDRRTLQRVAELCLEDGVALTQAQYLEKEEKFTLPPSLRVVVSVELTLEELDLAAQVI 465
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Sea Lamprey
Match: sptlc2a (serine palmitoyltransferase, long chain base subunit 2a [Source:ZFIN;Acc:ZDB-GENE-050522-23]) HSP 1 Score: 163.696 bits (413), Expect = 1.396e-44 Identity = 93/279 (33.33%), Postives = 148/279 (53.05%), Query Frame = 3
Query: 372 KTKPVLNLASFNFFNLIGN-EKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEE---QSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGV---AQRIR 1187
+ K V+N+ S+N+ N E A + +KYGVG C R G D H +LE +A F+ E ++ + GF+T + IPA +G +I +DE ++ G S + I+ FKHNDM +L LL + + P K + I++EG+Y G I LP++V LK +YK ++LDE S G +G GRGV ++FG+ D+D++ G+ + CGG+ G K +VD+ R++ ++ S+ P + ++ I E+G AQRIR
Sbjct: 113 RVKDVINMGSYNYLGFAENVGPCTEAAAQVAQKYGVGVCSTRQEMGNLDKHEELEKLVARFLGVEAAMAFGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSTATIRVFKHNDMVNLEKLLRDAIVNGQPRTHRPWK----KILILVEGIYSMEGSIVRLPEVVALKKRYKAYLYLDEAHSIGAVGPTGRGVVEYFGLHPQDVDVLMGTFTKSFGACGGYIGGRKDLVDYLRMNSHSAVYATSMSPPIIEQILQSMKCIMGEDGTTLGAQRIR 387
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Sea Lamprey
Match: alas2 (aminolevulinate, delta-, synthase 2 [Source:NCBI gene;Acc:64607]) HSP 1 Score: 109.383 bits (272), Expect = 7.479e-27 Identity = 69/252 (27.38%), Postives = 129/252 (51.19%), Query Frame = 3
Query: 450 QKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFS-------TVASAIPAYAK-RGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQR 1181
++ L+ +G G+ G R GT H++LE E+A+ + +++++ F T+A +P +G I++D G ++ G+ S F+HND HL +L+ +P+ +I + E ++ G +CPL ++ ++ +KY F+DE + G+ G +G G+ D V + +D+ITG+L A GG+ + ++D R G+ F+ +LPP++ GA + ++R+ EG A R
Sbjct: 1 RETLKMHGAGAGGTRNISGTSRFHVELEKELASLHGKDAALLFTSCFVANDSTLFTLAKMLPVLPHVKGCEIYSDAGNHASMIMGIRNSHVPKFVFRHNDPAHLEEVLKRS------DPSTPKI----VAFETVHSMDGAVCPLEEMCDIAHKYGAITFVDEVHAVGLYGTNGGGIGDRDNV-MHKMDIITGTLGKAFGCVGGYVASTASLIDTVRSYAAGFIFTTALPPMVLAGALESVRVLRSAEGQALR 241
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Yeast
Match: LCB1 (Component of serine palmitoyltransferase; responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine [Source:SGD;Acc:S000004911]) HSP 1 Score: 260.381 bits (664), Expect = 2.081e-80 Identity = 178/513 (34.70%), Postives = 256/513 (49.90%), Query Frame = 3
Query: 99 ELITSFI--SFHP-TYHLVFEIVLIISGLFLYFSRSYKPXXXXXX----XXXXXXXXXADWKPEPLV-PDGWQPNKIIQSKFEKSVISSFGKIVYFNEN----KTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEE--QSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVD-VTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSM--YWKLDSEDISPIKHIRL--------------RLNNTEERLEKAVNL-----AYQE----------------GLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMER 1481
+ I S+I S H Y EI LI+ G+ Y S+ + + +E + LI DW+PEPLV P +K ++ + N K V NLAS NF L E + E + ++ YGVG+CGP GFYG DVH LE ++A F + SV+Y F S +PA+ KRGDVI AD+ VS +Q L SRS + YF HNDM+ L LL E + E+ K PA I R FIV EG++ N GD+ PLP++ +LK KYK R+F+DET S GVLG GRG+++HF +D T ID+ GS+ TAL + GGF +G + HQR+ YCFSA LP S VL+++ + Q L ++SK + S S+ Y + S +S + H++L +L T L+K Y+E +LIT + + E PS+++ N A++ EE++ C +++
Sbjct: 40 QFIVSYIKKSHHDDPYRTTVEIGLILYGIIYYLSKPQQKKSLQAQKPNLSPQEIDALIEDWEPEPLVDPSATDEQSWRVAKTPVTMEMPIQNHITITRNNLQEKYTNVFNLASNNFLQLSATEPVKEVVKTTIKNYGVGACGPAGFYGNQDVHYTLEYDLAQFFGTQGSVLYGQDFCAAPSVLPAFTKRGDVIVADDQVSLPVQNALQLSRSTVYYFNHNDMNSLECLLNELTEQEKLEKLPA---IPRKFIVTEGIFHNSGDLAPLPELTKLKNKYKFRLFVDETFSIGVLGATGRGLSEHFNMDRATAIDITVGSMATALGSTGGFVLGDSVMCLHQRIGSNAYCFSACLPAYTVTSVSKVLKLMDSNNDAVQ--TLQKLSKSLHDSFASDDSLRSYVIVTSSPVSAVLHLQLTPAYRSRKFGYTCEQLFETMSALQKKSQTNKFIEPYEEEEKFLQSIVDHALINYNVLITRNTIVLKQETLPIVPSLKICCNAAMSPEELKNACESVKQ 547
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Yeast
Match: LCB2 (Component of serine palmitoyltransferase; responsible along with Lcb1p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine [Source:SGD;Acc:S000002469]) HSP 1 Score: 163.31 bits (412), Expect = 2.362e-44 Identity = 118/388 (30.41%), Postives = 194/388 (50.00%), Query Frame = 3
Query: 381 PVLNLASFNFFNLIGNE-KINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQ---SEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLP-PLLACGASVVLEMIRAEEGVAQ---RIRLNEISKKISSLLCSRLS--MYWKLDSEDIS-----PIKHIRLRLNNTEERLEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVGENLS 1499
P +NL+S+N+ ++ + + A +++ KY + S GPR GT D+H+K E +A F+ E+++V+S G+ T A+ A+ + ++ +DE +I+ G+ S + ++ FKH DM L L+ EQ + P K + I EGL+ G +C LPK+VELK KYK +F+DE S G +G GRGV + FGVD D+D++ G+ + GG+ ++++D RL +S S+P P+LA S L+ I E Q R++ + + L RL +Y DS I P K + R+ V +AY LI E+R +R ++ +LT E+I++ + VG+ L+
Sbjct: 156 PCMNLSSYNYLGFAQSKGQCTDAALESVDKYSIQSGGPRAQIGTTDLHIKAEKLVARFIGKEDALVFSMGYGTNANLFNAFLDKKCLVISDELNHTSIRTGVRLSGAAVRTFKHGDMVGLEKLIREQIVLGQPKTNRPWK----KILICAEGLFSMEGTLCNLPKLVELKKKYKCYLFIDEAHSIGAMGPTGRGVCEIFGVDPKDVDILMGTFTKSFGAAGGYIAADQWIIDRLRLDLTTVSYSESMPAPVLAQTIS-SLQTISGEICPGQGTERLQRIAFNSRYLRLALQRLGFIVYGVADSPVIPLLLYCPSKMPAFSRMMLQRRIAVVV-VAYPATPLI-ESR-------------VRFCMSASLTKEDIDYLLRHVSEVGDKLN 523
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Yeast
Match: HEM1 (5-aminolevulinate synthase; catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p; has a pyridoxal phosphate cofactor whose insertion is mediated by Mcx1p [Source:SGD;Acc:S000002640]) HSP 1 Score: 102.834 bits (255), Expect = 1.042e-23 Identity = 75/276 (27.17%), Postives = 123/276 (44.57%), Query Frame = 3
Query: 399 SFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYS--YGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVD--------------------VTD-IDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIR 1157
S ++ L + ++ + K + KYG G+ G R G L LE E+A E ++V+S Y + ++ + VIF+DE ++ G+ + K FKHND++ L LL+ + K I E +Y G + + KI +L KY FLDE + G+ G HG GV +H + V D +D+ITG+L + + GG+ S+ ++D R G+ F+ +LPP + GA+ + R
Sbjct: 120 SNDYLALSKHPEVLDAMHKTIDKYGCGAGGTRNIAGHNIPTLNLEAELATLHKKEGALVFSSCYVANDAVLSLLGQKMKDLVIFSDELNHASMIVGIKHANVKKHIFKHNDLNELEQLLQSYPKSVPK----------LIAFESVYSMAGSVADIEKICDLADKYGALTFLDEVHAVGLYGPHGAGVAEHCDFESHRASGIATPKTNDKGGAKTVMDRVDMITGTLGKSFGSVGGYVAASRKLIDWFRSFAPGFIFTTTLPPSVMAGATAAIRYQR 385
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Nematostella
Match: EDO36082 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJP9]) HSP 1 Score: 389.037 bits (998), Expect = 6.841e-131 Identity = 226/469 (48.19%), Postives = 318/469 (67.80%), Query Frame = 3
Query: 114 FISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXAD-WKPEPLVPDGWQ-PNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMY--WKLDSEDISPIKHIRL---RLNNTEER-LEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVGENL 1496
F S P YH++FEI L++ L+L S+SY+ E ++E+E + D W+P+PLVP P +I K + G V+ N + LNLA+FNF +GN +I +A LRKYGVGSCGPRGFYG+ DVHL LE+ +A FM+ EE+++YSYGFSTVASAIPAY+KRGDV+F D+GV FAIQ G+ ASRS++ +F+HNDMD L LL+EQ E+ KNP K +TR F+++EGLY+N+G I PLPK++ELK KYKVRI +DE+ SFGVLG GRGVT+++ + V D+DLI+ S+E +LAT GGF G+ +VVDHQRLSG GYCFSASLPP+LA A L+++ ++G+ N++ K + L L ++D E SPI H+R+ + + +ER L+K V+ A++E + +T ARYLK+ E +PSIR+++N LT+ EI V++ +++
Sbjct: 9 FPSQVPFYHVLFEIALVLWILWLLLSKSYRFRELSLELTEKEQEELIDEWQPQPLVPSSHPYPEDVITPKV---IDGKPGHKVHVNGQE---CLNLATFNFLGFVGNPRIESSAIDTLRKYGVGSCGPRGFYGSIDVHLHLEERLAKFMHTEEAILYSYGFSTVASAIPAYSKRGDVLFCDKGVCFAIQQGVTASRSRVMWFEHNDMDDLERLLKEQQEKDRKNPKKGSVTRRFLIVEGLYINHGTIAPLPKLLELKKKYKVRILVDESCSFGVLGKTGRGVTEYYDIPVDDVDLISVSMENSLATIGGFCCGTSFVVDHQRLSGAGYCFSASLPPMLATAAIEALDIMEEKDGM-----FNDLQMK-ARLFHQELKGIKGLRIDGERDSPIIHLRVAHTKGSTEDERLLKKIVDKAFEEKVALTIARYLKDQETFPVEPSIRITVNVDLTETEIHSAAQVIKNAADSI 465
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Nematostella
Match: EDO42990 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZR1]) HSP 1 Score: 172.555 bits (436), Expect = 2.242e-47 Identity = 99/328 (30.18%), Postives = 171/328 (52.13%), Query Frame = 3
Query: 309 QSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKI-NETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEE---QSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVA-QRIRLNEISKKISSLLCSRLSMYWKLDSEDISPI 1277
Q + V +G F KTK LNL S+N+ NE + + A+K++ K G+ C R +GT D+H++LE +A F+ E ++V+ GF+T ++ IP +GD+I +DE ++ G S + IK FKHND+ L + L Q + P + + I++EG+Y G + LP+IV +K KYK ++LDE S G +G GRGV+++FGV+ DID++ G+ + GG+ SK +++H R +++S+ P + +++I E+G + R+ +++ C + + + D SP+
Sbjct: 128 QIELVDRVSDDYGWTFNFTGTKTK-ALNLGSYNYLGFAENEGLCADEAEKSVHKNGIAVCSARHEFGTLDIHIELEKMVARFVGKESAMVFGMGFATNSTNIPVLVSKGDLIISDELNHSSLVLGARLSGATIKVFKHNDIKSLENKLRTSVVQGQPRTHRPWR----KILIIVEGVYSMEGSLVRLPEIVAIKKKYKAYLYLDEAHSIGAVGPTGRGVSEYFGVNPADIDIMMGTFTKSFGAAGGYIASSKEIINHIRGCSHSAAYASSMSPPVTLQIYTSMKIILGEDGTNLGKQRIQALAENTRYFRCRLKELGFIIYGHDESPV 450
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Nematostella
Match: EDO46206 (5-aminolevulinate synthase [Source:UniProtKB/TrEMBL;Acc:A7RQQ4]) HSP 1 Score: 111.309 bits (277), Expect = 5.209e-26 Identity = 73/293 (24.91%), Postives = 140/293 (47.78%), Query Frame = 3
Query: 360 FNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKR--GDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSR 1232
F+ K + S ++ + + ++ + A++ + +GVG+ G R GT H +LE +A E +++++ + + + K G +IF+D G ++ G+ S +K F+HND +HL A + E ++ GDI P+ ++ ++ +KY F+DE + G+ G HG GV + G+ + D+D+I+G+L A GG+ G+ ++D R G G+ F+ +LPP+ A +E++ +EG R + ++ + L R
Sbjct: 134 FSGAANKDISVWCSNDYLGMSRHPEVLKVARETIDVHGVGAGGTRNISGTSSYHEQLEKVLAQLHQKEAALLFTSCYVANDTTLYTLGKHLPGCLIFSDAGNHASMIQGIRNSGAKKFIFRHNDPEHL----------GKLLAAADPAAPKIVAFETVHSMTGDISPIKQLCDVAHKYGALTFVDEVHAVGLYGHHGGGVGERDGL-LADMDIISGTLGKAFGVIGGYIAGTASLIDTIRSYGAGFIFTTALPPITVKSAIKSIEILSGDEGRDLRRVHQSVVARLRNKLVQR 415
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Nematostella
Match: EDO38490 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCT4]) HSP 1 Score: 107.457 bits (267), Expect = 2.925e-25 Identity = 80/264 (30.30%), Postives = 128/264 (48.48%), Query Frame = 3
Query: 366 ENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGS-KYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMI 1154
E + +LN + N+ L N ++ A++AL KYG G R GT D+H LE +I+ F E++++Y+ + + D +F+DE ++ G+ R+K +KH D+ L EE +K ARI I +G++ G + PLP+I +L KY +F+DE + G LGD GRG TD + +D+I +L AL G +V R + Y +S +LPP + A+ VL+M+
Sbjct: 52 EGRESKILNFCANNYLGLSSNAEVVNAAKEALMKYGNGLSSVRFICGTQDIHKTLEAKISKFHGMEDAILYACCYDANTGLFESLLTAEDAVFSDELNHASMIDGIRLCRAKKFKYKHIDVQDL--------EEKLKEADGARI--KLIASDGVFSMDGSMAPLPEICDLADKYGALVFIDECHATGFLGDTGRG-TDEYTGTRGRVDIINSTLGKALGGAAGGYTTGPSQLVQMLRQKSRPYLYSNTLPPAVVGSATKVLDML 304
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Nematostella
Match: EDO27220 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T9V2]) HSP 1 Score: 104.375 bits (259), Expect = 2.849e-24 Identity = 72/273 (26.37%), Postives = 132/273 (48.35%), Query Frame = 3
Query: 378 KPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETAL-ATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLN 1193
+ VLN + N+ L + ++ + A+ AL +G G R GT D+H +LE ++A F E++++Y+ F D I +D +I G+ ++ +++NDM+ L + L + +E A R IV +G++ G + PL KI +L KY+ + +DE + G +G G+G + V + +D+ITG+ AL GG++ K +++ R + Y FS SL P + + V E++ + + ++ N
Sbjct: 35 ETVLNFCANNYLGLSSHPEVVQAAKDALDSHGFGMSSVRFICGTQDIHKELEQKVAQFYGTEDTILYAAAFDANGGVFEPLLGEQDCIISDSLNHASIIDGVRLCKAARYRYQNNDMNDLEAQLIKATE------AGHRFK--LIVTDGVFSMDGLVAPLDKICDLADKYEAMVMVDECHAAGFIGATGKGTLEAKNV-MGRVDIITGTFGKALGGAMGGYTTAKKEIIEILRQRSRPYLFSNSLAPSIVGASLKVFELLEKDTSLRDKLEWN 298
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Medaka
Match: sptlc1 (serine palmitoyltransferase long chain base subunit 1 [Source:NCBI gene;Acc:101173642]) HSP 1 Score: 412.535 bits (1059), Expect = 1.506e-139 Identity = 225/463 (48.60%), Postives = 312/463 (67.39%), Query Frame = 3
Query: 99 ELITSFISFHPTYHLVFEIVLIISGL-FLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISS--FGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGV--AQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLR-----LNNTEERLEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIE 1457
E++ +F P YHL+ E +LI+ + L+FS++YKP ET KLT+KE+E+LI +W+PEPLVP P V++ KI+ + T N ASFNF L+ ++++ + A +L+KYGVG+CGPRGFYGTFDVHL+LE +A FM EE+++YSYGF+T+ASAIPAY+KRGD+IF DE F+IQ GL ASRS IKYFKHNDM+ L LL+EQ E KNP KAR+TR FIV+EGLY+N D+CPLP++V LKYKYKVRIFL+E++SFGVLG+HG+GVT+HFGV++ DIDLI+ ++E A+A+ GGF G +V+DHQRLSGQGYCFSASLPP+LA A L ++ + + + R +++ + + + KL SP H++L ++ + L V+ + +T ARYL++ E P PSIR+ + TDE+I+
Sbjct: 11 EMVQAFYE-APAYHLILEGILILWIVRLLFFSKTYKPHETYKLTEKEKEDLIEEWQPEPLVP----PVSKDHPSLNYDVVTGPPSHKIIINGKECT----NFASFNFLGLLDSDRVKDKALASLKKYGVGTCGPRGFYGTFDVHLELESRLAKFMRTEEAIIYSYGFATIASAIPAYSKRGDIIFVDEAACFSIQKGLQASRSFIKYFKHNDMEDLERLLKEQELEDQKNPRKARVTRKFIVVEGLYINTADVCPLPELVRLKYKYKVRIFLEESMSFGVLGEHGKGVTEHFGVNIDDIDLISANMENAVASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPMLAAAAIEALSIMEEDPEIFSVLKRRCSQVHQALQGIPG------LKLVGVPFSPALHLQLERSSGCRSSDLQLLRSIVDHCLDRHVALTVARYLEKEERFMPPPSIRVVVTVEQTDEDIQ 458
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Medaka
Match: sptlc2b (serine palmitoyltransferase 2 [Source:NCBI gene;Acc:101165525]) HSP 1 Score: 159.073 bits (401), Expect = 6.927e-42 Identity = 94/305 (30.82%), Postives = 154/305 (50.49%), Query Frame = 3
Query: 378 KPVLNLASFNFFNLIGNEKINETAQ-KALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEE---QSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEG-VAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPI 1277
K V+N+ S+N+ N +A + YGVG R G D+H +LE +A F+ E S+ + GF+T + IP +G +I +DE ++ G S S I+ FKHN+M L LL + + P K + IV+EG+Y G I LP+++ LK +YK ++LDE S G LG +GRGV D+FG+D D+D++ G+ + GG+ G K ++D+ R ++ S+ P +A +++I E+G + RL ++S+ + M + + D SP+
Sbjct: 172 KDVINMGSYNYLGFAENTGACASAAIETTHAYGVGVASTRCEIGNLDIHEELEQLVARFLGVESSMAFGMGFATNSMNIPPLTGKGCLILSDELNHASLVLGARLSGSTIRVFKHNNMQSLEKLLRDAIAHGQPRTHRPWK----KILIVVEGIYSMEGSIVRLPEVIALKKRYKAYLYLDEAHSIGALGPNGRGVVDYFGLDPKDVDIMMGTFTKSFGAAGGYIGGRKELIDYLRCHSHSALYATSMSPPVAQQIISSMKIIMGEDGSTLGKDRLRQLSENTTYFRRKLREMGFIIYGNDDSPV 472
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Medaka
Match: ENSORLT00000022091.2 (serine palmitoyltransferase 2-like [Source:NCBI gene;Acc:101156930]) HSP 1 Score: 155.992 bits (393), Expect = 4.327e-41 Identity = 90/311 (28.94%), Postives = 157/311 (50.48%), Query Frame = 3
Query: 360 FNENKTKPVLNLASFNFFNLIGNE-KINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQ---SEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRI-RLNEISKKISSLLCSRLSMYWKLDSEDISPI 1277
+N K V+NL S+N+ N ++A + +R YG+G R G D H ++E ++A F+ E ++ + GF+T + IPA +G +I +DE ++ G S + I+ FKHN+M L LL E + P K + IV+EG+Y G I LP+++ LK +YK ++LDE S G LG GRGV D+F +D D+D++ G+ + GG+ G + ++++ R ++AS+ P + ++ I ++G + RL ++++ + M + + D SP+
Sbjct: 125 YNGRTMKDVINLGSYNYLGFAENTGPCADSAAQVVRTYGIGVASTRQEIGNLDKHEEMEKQVAKFLGVESAMAFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRVFKHNNMQCLEKLLSEAIIYGQPRTHRPWK----KILIVVEGIYSMEGSIVRLPEVITLKKRYKAYLYLDEAHSIGALGHRGRGVVDYFDLDPRDVDVLMGTFTKSFGAAGGYIAGKRELIEYLRSHSHSAVYAASMSPPVVEQIITSMKCIMGDDGTSIGCKRLQQLAENTTYFRRRLREMGFIIYGNDDSPV 431
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Medaka
Match: ENSORLT00000013273.2 (serine palmitoyltransferase 2-like [Source:NCBI gene;Acc:101156930]) HSP 1 Score: 156.377 bits (394), Expect = 4.500e-41 Identity = 90/311 (28.94%), Postives = 157/311 (50.48%), Query Frame = 3
Query: 360 FNENKTKPVLNLASFNFFNLIGNE-KINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQ---SEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRI-RLNEISKKISSLLCSRLSMYWKLDSEDISPI 1277
+N K V+NL S+N+ N ++A + +R YG+G R G D H ++E ++A F+ E ++ + GF+T + IPA +G +I +DE ++ G S + I+ FKHN+M L LL E + P K + IV+EG+Y G I LP+++ LK +YK ++LDE S G LG GRGV D+F +D D+D++ G+ + GG+ G + ++++ R ++AS+ P + ++ I ++G + RL ++++ + M + + D SP+
Sbjct: 173 YNGRTMKDVINLGSYNYLGFAENTGPCADSAAQVVRTYGIGVASTRQEIGNLDKHEEMEKQVAKFLGVESAMAFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRVFKHNNMQCLEKLLSEAIIYGQPRTHRPWK----KILIVVEGIYSMEGSIVRLPEVITLKKRYKAYLYLDEAHSIGALGHRGRGVVDYFDLDPRDVDVLMGTFTKSFGAAGGYIAGKRELIEYLRSHSHSAVYAASMSPPVVEQIITSMKCIMGDDGTSIGCKRLQQLAENTTYFRRRLREMGFIIYGNDDSPV 479
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Medaka
Match: ENSORLT00000042858.1 (serine palmitoyltransferase 2-like [Source:NCBI gene;Acc:101156930]) HSP 1 Score: 156.377 bits (394), Expect = 7.499e-41 Identity = 90/311 (28.94%), Postives = 157/311 (50.48%), Query Frame = 3
Query: 360 FNENKTKPVLNLASFNFFNLIGNE-KINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQ---SEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRI-RLNEISKKISSLLCSRLSMYWKLDSEDISPI 1277
+N K V+NL S+N+ N ++A + +R YG+G R G D H ++E ++A F+ E ++ + GF+T + IPA +G +I +DE ++ G S + I+ FKHN+M L LL E + P K + IV+EG+Y G I LP+++ LK +YK ++LDE S G LG GRGV D+F +D D+D++ G+ + GG+ G + ++++ R ++AS+ P + ++ I ++G + RL ++++ + M + + D SP+
Sbjct: 173 YNGRTMKDVINLGSYNYLGFAENTGPCADSAAQVVRTYGIGVASTRQEIGNLDKHEEMEKQVAKFLGVESAMAFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRVFKHNNMQCLEKLLSEAIIYGQPRTHRPWK----KILIVVEGIYSMEGSIVRLPEVITLKKRYKAYLYLDEAHSIGALGHRGRGVVDYFDLDPRDVDVLMGTFTKSFGAAGGYIAGKRELIEYLRSHSHSAVYAASMSPPVVEQIITSMKCIMGDDGTSIGCKRLQQLAENTTYFRRRLREMGFIIYGNDDSPV 479
BLAST of Serine palmitoyltransferase 1 vs. Planmine SMEST
Match: SMESG000052311.1 (SMESG000052311.1) HSP 1 Score: 867.84 bits (2241), Expect = 0.000e+0 Identity = 441/475 (92.84%), Postives = 447/475 (94.11%), Query Frame = 3
Query: 69 MESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVGEN 1493
MESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPLETIKLTKKEEEELIADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEGLLITEA + + + L+ +T EE E+V N
Sbjct: 1 MESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPLETIKLTKKEEEELIADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEGLLITEASEIITERVRDGRLKDALTTKPTITTEERNQLAKTYEKVESN 475
BLAST of Serine palmitoyltransferase 1 vs. Planmine SMEST
Match: SMESG000080769.1 (SMESG000080769.1) HSP 1 Score: 866.3 bits (2237), Expect = 0.000e+0 Identity = 441/475 (92.84%), Postives = 447/475 (94.11%), Query Frame = 3
Query: 69 MESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEGLLITEARYLKESEYKCPKPSIRLSINCALTDEEIEFFCNVMERVGEN 1493
MESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPLETIKLTKKEEEELIADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEGLLITEA + + + L+ +T EE E+V N
Sbjct: 1 MESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPLETIKLTKKEEEELIADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEGLLITEASEIITERVRDGRLKDALTTKPTITTEERNQPAKTYEKVESN 475
BLAST of Serine palmitoyltransferase 1 vs. Planmine SMEST
Match: SMESG000052311.1 (SMESG000052311.1) HSP 1 Score: 865.914 bits (2236), Expect = 0.000e+0 Identity = 438/446 (98.21%), Postives = 441/446 (98.88%), Query Frame = 3
Query: 69 MESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEGLLITEARYLKESEYKCPK 1406
MESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPLETIKLTKKEEEELIADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEGLLITEAR K++ Y+ K
Sbjct: 1 MESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPLETIKLTKKEEEELIADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEGLLITEARKKKQNSYENKK 446
BLAST of Serine palmitoyltransferase 1 vs. Planmine SMEST
Match: SMESG000080769.1 (SMESG000080769.1) HSP 1 Score: 860.907 bits (2223), Expect = 0.000e+0 Identity = 435/435 (100.00%), Postives = 435/435 (100.00%), Query Frame = 3
Query: 69 MESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEGLLITEAR 1373
MESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPLETIKLTKKEEEELIADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEGLLITEAR
Sbjct: 1 MESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPLETIKLTKKEEEELIADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEGLLITEAR 435
BLAST of Serine palmitoyltransferase 1 vs. Planmine SMEST
Match: SMESG000052311.1 (SMESG000052311.1) HSP 1 Score: 860.907 bits (2223), Expect = 0.000e+0 Identity = 435/435 (100.00%), Postives = 435/435 (100.00%), Query Frame = 3
Query: 69 MESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPXXXXXXXXXXXXXXXADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEGLLITEAR 1373
MESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPLETIKLTKKEEEELIADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEGLLITEAR
Sbjct: 1 MESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPLETIKLTKKEEEELIADWKPEPLVPDGWQPNKIIQSKFEKSVISSFGKIVYFNENKTKPVLNLASFNFFNLIGNEKINETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEGVAQRIRLNEISKKISSLLCSRLSMYWKLDSEDISPIKHIRLRLNNTEERLEKAVNLAYQEGLLITEAR 435 The following BLAST results are available for this feature:
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Serine palmitoyltransferase 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Serine palmitoyltransferase 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 3
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Serine palmitoyltransferase 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Serine palmitoyltransferase 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30011350 ID=SMED30011350|Name=Serine palmitoyltransferase 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1627bpback to top protein sequence of SMED30011350-orf-1 >SMED30011350-orf-1 ID=SMED30011350-orf-1|Name=SMED30011350-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=480bp MESEIENSWKELITSFISFHPTYHLVFEIVLIISGLFLYFSRSYKPLETIback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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