Tetraspanin

Overview
NameTetraspanin
Smed IDSMED30011329
Length (bp)1044
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Tetraspanin (SMED30011329) t-SNE clustered cells

Violin plots show distribution of expression levels for Tetraspanin (SMED30011329) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Tetraspanin (SMED30011329) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Tetraspanin (SMED30011329) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30011329

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30011329h1SMcG0001380 dd_Smed_v4_5409_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30011329h1SMcG0001380 dd_Smed_v4_5409_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30011329h1SMcG0001380 dd_Smed_v4_5409_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30011329h1SMcG0001380 Contig49539uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30011329h1SMcG0001380 Contig49539newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30011329h1SMcG0001380 Contig4595GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30011329h1SMcG0016518 Contig4595GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
protonephridiaSMED30011329h1SMcG0001380 dd_Smed_v6_5409_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Tetraspanin vs. Ensembl Fly
Match: Tsp66E (gene:FBgn0035936 transcript:FBtr0076507)

HSP 1 Score: 50.8322 bits (120), Expect = 5.839e-7
Identity = 59/254 (23.23%), Postives = 110/254 (43.31%), Query Frame = 3 
Query:  186 IIGSVFLIFGIWIKVNKNNLFKILRSVTLDDTVASFSNTSSSALDFVAXXXXXXXXXXXXXXXXXXXXSCKENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCAT--SQKTQLNTEGCLRVVLN-LVKSNLVAVICICIVLCMFEVLCILFA 938
            ++G++    G+W+ V+K++L  +L+ V   + +  F  T   A++ +A  L+++G  +F + F G  G+ +E++C+L TY   +  +++A+I  G      K K     K  L+  +       L  N    + ++  +M    CCGI D  DF D    W       N++ P  CC L    +  P              D  C T  S       +GC  V    L++   + ++ I + +    ++ + FA
Sbjct:   23 VLGTIIFGVGLWLAVDKHSLIALLKLVE-SERIEQF--TQPQAIEQLAYVLLVIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQTTITSY---SLGENVDATSLMWNQLMGNFGCCGINDYHDF-DASPAWVNG--KGNRTIPDACCILKDVAKLVPR-------------DEDCTTNPSDSNSFYKKGCYEVFTEWLIRQRELVIVAIAVGIVHLVLIILAFA 254
[Close]
BLAST of Tetraspanin vs. Ensembl Fly
Match: Tsp66E (gene:FBgn0035936 transcript:FBtr0076506)

HSP 1 Score: 50.8322 bits (120), Expect = 5.839e-7
Identity = 59/254 (23.23%), Postives = 110/254 (43.31%), Query Frame = 3 
Query:  186 IIGSVFLIFGIWIKVNKNNLFKILRSVTLDDTVASFSNTSSSALDFVAXXXXXXXXXXXXXXXXXXXXSCKENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCAT--SQKTQLNTEGCLRVVLN-LVKSNLVAVICICIVLCMFEVLCILFA 938
            ++G++    G+W+ V+K++L  +L+ V   + +  F  T   A++ +A  L+++G  +F + F G  G+ +E++C+L TY   +  +++A+I  G      K K     K  L+  +       L  N    + ++  +M    CCGI D  DF D    W       N++ P  CC L    +  P              D  C T  S       +GC  V    L++   + ++ I + +    ++ + FA
Sbjct:   23 VLGTIIFGVGLWLAVDKHSLIALLKLVE-SERIEQF--TQPQAIEQLAYVLLVIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQTTITSY---SLGENVDATSLMWNQLMGNFGCCGINDYHDF-DASPAWVNG--KGNRTIPDACCILKDVAKLVPR-------------DEDCTTNPSDSNSFYKKGCYEVFTEWLIRQRELVIVAIAVGIVHLVLIILAFA 254
[Close]
BLAST of Tetraspanin vs. Ensembl Fly
Match: Tsp66E (gene:FBgn0035936 transcript:FBtr0076508)

HSP 1 Score: 50.8322 bits (120), Expect = 5.839e-7
Identity = 59/254 (23.23%), Postives = 110/254 (43.31%), Query Frame = 3 
Query:  186 IIGSVFLIFGIWIKVNKNNLFKILRSVTLDDTVASFSNTSSSALDFVAXXXXXXXXXXXXXXXXXXXXSCKENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCAT--SQKTQLNTEGCLRVVLN-LVKSNLVAVICICIVLCMFEVLCILFA 938
            ++G++    G+W+ V+K++L  +L+ V   + +  F  T   A++ +A  L+++G  +F + F G  G+ +E++C+L TY   +  +++A+I  G      K K     K  L+  +       L  N    + ++  +M    CCGI D  DF D    W       N++ P  CC L    +  P              D  C T  S       +GC  V    L++   + ++ I + +    ++ + FA
Sbjct:   23 VLGTIIFGVGLWLAVDKHSLIALLKLVE-SERIEQF--TQPQAIEQLAYVLLVIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQTTITSY---SLGENVDATSLMWNQLMGNFGCCGINDYHDF-DASPAWVNG--KGNRTIPDACCILKDVAKLVPR-------------DEDCTTNPSDSNSFYKKGCYEVFTEWLIRQRELVIVAIAVGIVHLVLIILAFA 254
[Close]
BLAST of Tetraspanin vs. Ensembl Xenopus
Match: gpr88 (G protein-coupled receptor 88 [Source:Xenbase;Acc:XB-GENE-984668])

HSP 1 Score: 49.6766 bits (117), Expect = 2.307e-6
Identity = 42/186 (22.58%), Postives = 83/186 (44.62%), Query Frame = 3 
Query:  396 KENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEVLCILFACYILR 953
            +ENKC+L  +   +  + LA++   +   + +   ENL K+     +KK ++G    ++ +F+  + S+M    CCG+    DF D     R + +      P  CC+       +  S+       + ++   C T  +   N +GC  V++N V+  +     + I +   E+L ++FA  + R
Sbjct:   78 RENKCLLVFFFMFILVIFLAELSAAILAFLFR---ENLSKDFFAREVKKHYHG--DNSTEVFSSTWNSIMITFGCCGVNGPEDFNDAH---RFRAMHPFAPVPEACCR------REVQSRAG-----KIVSRAECLTGGENYQNRQGCYSVIVNSVEPYVYIAGALAIGVLAIELLSMVFAMCLFR 244
[Close]
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Tspan3 (tetraspanin 3 [Source:MGI Symbol;Acc:MGI:1928098])

HSP 1 Score: 51.2174 bits (121), Expect = 5.782e-7
Identity = 51/185 (27.57%), Postives = 93/185 (50.27%), Query Frame = 3 
Query:  396 KENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEVLCILFACYIL 950
            +E++C L T+ F++  V + ++ + V   V + K EN +  S++ + K  +NG   TNS   ++    +  Q+ CCGI + +D+ +TD  W ++   KNQS P+ CC+       +     N +     +A+PS        L  EGC  +V+  ++  L+ VI   +     ++L +L AC +L
Sbjct:   77 RESRCGLATFVFILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKT-YNG---TNSDAASRAIDYVQRQLHCCGIHNYSDWENTD--WFKET--KNQSVPLSCCR-------ETAKSCNGS-----LANPS-------DLYAEGCEALVVKKLQEILMHVIWAALAFAAIQLLGMLCACIVL 234
[Close]
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Tspan3 (tetraspanin 3 [Source:MGI Symbol;Acc:MGI:1928098])

HSP 1 Score: 50.8322 bits (120), Expect = 8.376e-7
Identity = 51/185 (27.57%), Postives = 93/185 (50.27%), Query Frame = 3 
Query:  396 KENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEVLCILFACYIL 950
            +E++C L T+ F++  V + ++ + V   V + K EN +  S++ + K  +NG   TNS   ++    +  Q+ CCGI + +D+ +TD  W ++   KNQS P+ CC+       +     N +     +A+PS        L  EGC  +V+  ++  L+ VI   +     ++L +L AC +L
Sbjct:   80 RESRCGLATFVFILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKT-YNG---TNSDAASRAIDYVQRQLHCCGIHNYSDWENTD--WFKET--KNQSVPLSCCR-------ETAKSCNGS-----LANPS-------DLYAEGCEALVVKKLQEILMHVIWAALAFAAIQLLGMLCACIVL 237
[Close]
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Tspan1 (tetraspanin 1 [Source:MGI Symbol;Acc:MGI:1914055])

HSP 1 Score: 49.2914 bits (116), Expect = 2.146e-6
Identity = 56/241 (23.24%), Postives = 104/241 (43.15%), Query Frame = 3 
Query:  156 MKRFLKIKIMIIGSVFLIFGIWIKVNKNNLFKILRSVTLDDTVASFSNTSSSALDFV--AXXXXXXXXXXXXXXXXXXXXSCKENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATSQKTQLNTEGCLRVVLNLVKSN 872
            M     + I + G+  L  GIW+ V+  +  K+            F + SSSA+ FV     LI  G  +F++ F GC+G+  ENKC+L  +  ++  + +A+I   V   V     E  L   +   ++K++        + FT+++ + M ++ CCG  + TDF  +      + V +N+  P  CC        +P                 C   +   +  +GC + +L+ +++N
Sbjct:   10 MMFLFNLLIFLCGAALLAVGIWVSVDGTSFLKV------------FGSLSSSAMQFVNVGYFLIAAGAVLFILGFLGCYGAHSENKCVLMMFFSILLIIFIAEIAGAVVALVYTTLAEQFLTLLVVPAIEKDYG-----YQTDFTQVWNTTMEELHCCGFNNYTDFNAS------RFVKENKVFPPPCCANPGNHTVEP-----------------CTEEKAKSMKVQGCFKEILHRIRAN 210
[Close]
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Tspan1 (tetraspanin 1 [Source:MGI Symbol;Acc:MGI:1914055])

HSP 1 Score: 48.9062 bits (115), Expect = 2.366e-6
Identity = 56/241 (23.24%), Postives = 104/241 (43.15%), Query Frame = 3 
Query:  156 MKRFLKIKIMIIGSVFLIFGIWIKVNKNNLFKILRSVTLDDTVASFSNTSSSALDFV--AXXXXXXXXXXXXXXXXXXXXSCKENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATSQKTQLNTEGCLRVVLNLVKSN 872
            M     + I + G+  L  GIW+ V+  +  K+            F + SSSA+ FV     LI  G  +F++ F GC+G+  ENKC+L  +  ++  + +A+I   V   V     E  L   +   ++K++        + FT+++ + M ++ CCG  + TDF  +      + V +N+  P  CC        +P                 C   +   +  +GC + +L+ +++N
Sbjct:   10 MMFLFNLLIFLCGAALLAVGIWVSVDGTSFLKV------------FGSLSSSAMQFVNVGYFLIAAGAVLFILGFLGCYGAHSENKCVLMMFFSILLIIFIAEIAGAVVALVYTTLAEQFLTLLVVPAIEKDYG-----YQTDFTQVWNTTMEELHCCGFNNYTDFNAS------RFVKENKVFPPPCCANPGNHTVEP-----------------CTEEKAKSMKVQGCFKEILHRIRAN 210
[Close]
BLAST of Tetraspanin vs. UniProt/SwissProt
Match: sp|Q9QY33|TSN3_MOUSE (Tetraspanin-3 OS=Mus musculus OX=10090 GN=Tspan3 PE=1 SV=1)

HSP 1 Score: 51.2174 bits (121), Expect = 4.045e-6
Identity = 51/185 (27.57%), Postives = 93/185 (50.27%), Query Frame = 3 
Query:  396 KENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEVLCILFACYIL 950
            +E++C L T+ F++  V + ++ + V   V + K EN +  S++ + K  +NG   TNS   ++    +  Q+ CCGI + +D+ +TD  W ++   KNQS P+ CC+       +     N +     +A+PS        L  EGC  +V+  ++  L+ VI   +     ++L +L AC +L
Sbjct:   77 RESRCGLATFVFILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKT-YNG---TNSDAASRAIDYVQRQLHCCGIHNYSDWENTD--WFKET--KNQSVPLSCCR-------ETAKSCNGS-----LANPS-------DLYAEGCEALVVKKLQEILMHVIWAALAFAAIQLLGMLCACIVL 234
[Close]
BLAST of Tetraspanin vs. UniProt/SwissProt
Match: sp|Q6AYR9|TSN1_RAT (Tetraspanin-1 OS=Rattus norvegicus OX=10116 GN=Tspan1 PE=2 SV=1)

HSP 1 Score: 50.0618 bits (118), Expect = 8.080e-6
Identity = 63/250 (25.20%), Postives = 110/250 (44.00%), Query Frame = 3 
Query:  156 MKRFLKIKIMII---------GSVFLIFGIWIKVNKNNLFKILRSVTLDDTVASFSNTSSSALDFV--AXXXXXXXXXXXXXXXXXXXXSCKENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATSQKTQLNTEGCLRVVLNLVKSN 872
            M+ F  IK+M+I         G+  L  GIW+ V+  +  K            +F + SSSA+ FV     LI  G  +F++ F GC+G+  ENKC+L  +  ++  + +A+I   V   V     E  L   +   ++K++        + FT+++ S M  + CCG  + TDF  +      + V +N+  P  CC  N                +    +P C   +   +N +GC + +L  +++N
Sbjct:    1 MQCFKFIKVMMILFNLLIFLCGAALLAVGIWVSVDGTSFLK------------AFGSLSSSAMQFVNVGYFLIAAGAVLFILGFLGCYGAHSENKCVLMMFFSILLIIFIAEIAGAVVALVYTTMAEQFLTFLVVPAIEKDYG-----YQTEFTQVWNSTMEGLHCCGFNNYTDFNSS------RFVKENKVFPPFCCANN---------------TDSHTVEP-CTEDKAKSMNVQGCFKQILQKIRTN 211
[Close]
BLAST of Tetraspanin vs. TrEMBL
Match: A0A267EG05 (Tetraspanin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig020731g1 PE=3 SV=1)

HSP 1 Score: 85.8853 bits (211), Expect = 2.836e-15
Identity = 77/292 (26.37%), Postives = 155/292 (53.08%), Query Frame = 3 
Query:  171 KIKIMIIGSVFLIFG-------IWIKVNKNNLFKILRSVTL------DDTVASFSNTSSSALDFVAXXXXXXXXXXXXXXXXXXXXSCKENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXF---NGILSTNS---SLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSH---PIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCA-TSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEVLCILFACYILRKDGK*QQN 977
            K+ ++I+  VFL+ G       IW+ V+ +++FK++   T       ++T+ S+  +S+S L   A  +++ G   F+I FCGC G+ +E+ C+L  Y+  VS V++ +I  G+  GV + +    +  +L+ +    +   N  +S +S   ++F+ +       M CCG++  +D T  +  W       N      P+ CCK+N+  + +  S  N T +++++ D +C   +  +Q+N EGC   + + +    +A+I + I++ MFE++C++ AC +++K    +QN
Sbjct:    7 KLVLVIVNIVFLLAGAAIVGVSIWVIVSADSMFKLVHLATQGSDNINNETLMSY-KSSTSTLVAAAYVILVFGALSFLIGFCGCCGAIRESSCLLSIYAGAVSIVLIVEIAGGIAAGVFRAQIGTEMLPTLRRLEATRYLPINLAVSNDSNPNAVFSSLVNYAQVSMSCCGVSSMSDITGVNTLWTNSSRQYNGKTIVVPVTCCKMNK--KDELLSHQNWTRIDDYLIDRNCPYNASSSQINKEGCYDKLNSYIDRYTLAIIVVGILVGMFEIICVVMACSMVQKIRSERQN 295
[Close]
BLAST of Tetraspanin vs. TrEMBL
Match: A0A267FTC4 (Tetraspanin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig020731g3 PE=3 SV=1)

HSP 1 Score: 85.5001 bits (210), Expect = 3.284e-15
Identity = 78/292 (26.71%), Postives = 155/292 (53.08%), Query Frame = 3 
Query:  171 KIKIMIIGSVFLIFG-------IWIKVNKNNLFKILRSVTL------DDTVASFSNTSSSALDFVAXXXXXXXXXXXXXXXXXXXXSCKENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXF---NGILSTNS---SLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSH---PIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCA-TSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEVLCILFACYILRKDGK*QQN 977
            K+ ++I+  VFL+ G       IW+ V+ +++FK++   T       ++T+ S+  +S+S L   A  +++ G   F+I FCGC G+ +E+ C+L  Y+  VS V++ +I  G+  GV + +    +  +LK +    +   N  +S +S   ++F+ +       M CCG++  +D T  +  W       N      P+ CCK+N+  + +  S  N T +++++ D +C   +  +Q+N EGC   + + +    +A+I + I++ MFE++C++ AC +++K    +QN
Sbjct:    7 KLVLVIVNIVFLLAGAAIVGVSIWVIVSADSMFKLVHLATQGSDNINNETLMSY-KSSTSTLVAAAYVILVFGALSFLIGFCGCCGAIRESSCLLSIYAGAVSIVLIVEIAGGIAAGVFRAQIGTEMLPTLKRLEATRYLPINLAVSNDSNPNAVFSSLVNYAQVSMSCCGVSSMSDITGVNTLWTNSSRQYNGKTIVVPVTCCKMNK--KDELLSHQNWTRIDDYLIDRNCPYNASSSQINKEGCYDKLNSYIDRYTLAIIVVGILVGMFEIICVVMACSMVQKIRSERQN 295
[Close]
BLAST of Tetraspanin vs. TrEMBL
Match: A0A267FNP2 (Tetraspanin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig030520g2 PE=3 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 9.552e-15
Identity = 76/283 (26.86%), Postives = 150/283 (53.00%), Query Frame = 3 
Query:  156 MKRFLKIKIMII----GSVFLIFGIWIKVNKNNLFKILRSVTLDDTV--ASFSN--TSSSALDFVAXXXXXXXXXXXXXXXXXXXXSCKENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGI-LSTNSSLFTKIFTSMM----FQMKCCGITDETDFTDTDQNW---RQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEVLCILFACYILRK 956
            M +F+ + + II    G V     IW+ V+K+ +F +++ VT D  V  A+  N   S+S L   A  +++ G    V+ FCGC G+ KE+ C+L  Y+  +S V++A+I   +   V + +  + L+  L  + ++ F  + L+ N+     + T+ +       +CCG+T++TD T  D  W    ++   K Q+ P+ CC++  T + +   K +   V +++ DP+C  +    + TE C + +  ++    + +I +CIV+ + E++C++ AC +++K
Sbjct:    5 MNKFILVAVNIIFLLAGLVITGIAIWVIVSKDTMFDLVQLVTKDVDVDRATLDNYMNSTSMLLAAAYIVLVFGCISIVVGFCGCCGALKESSCLLMFYAIAISIVLIAEIVGAILAAVFRNQIGDKLQPRLVTLEREHFLPLGLTLNNKTTDAVITAWVNYAQTSFECCGVTNQTDITGPDTLWTRSHREFNGKLQTMPVTCCRMKAT-RSELLGKQDWNNVADYLEDPACPNTGNGVV-TESCYKKIDGMINKYSMPIIIVCIVVGLCEIICVVMACSLIQK 285
[Close]
BLAST of Tetraspanin vs. TrEMBL
Match: A0A1I8H836 (Tetraspanin OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 2.872e-13
Identity = 51/204 (25.00%), Postives = 105/204 (51.47%), Query Frame = 3 
Query:  396 KENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXF---NGILSTNS---SLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSH---PIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCA-TSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEVLCILFACYILRKDGK*QQN 977
            +E+ C+L  Y+  VS V++ +I  G+  GV + +    +  +L+ +    +   N  +S +S   ++F+ +       M CCG++  +D T  +  W       N      P+ CCK+N+  +    S  N T +++++ D +C   +  +Q+N EGC   + + +    +A+I + I++ MFE++C++ AC +++K    +QN
Sbjct:   47 RESSCLLSIYAGAVSIVLIVEIAGGIAAGVFRAQIGTEMLPTLRRLEATRYLPINLAVSNDSNPNAVFSSLVNYAQVSMSCCGVSSMSDITGVNTLWTNSSRQYNGKTIVVPVTCCKMNKKDELL--SHQNWTRIDDYLIDRNCPYNASSSQINKEGCYDKLNSYIDRYTLAIIVVGILVGMFEIICVVMACSMVQKIRSERQN 248
[Close]
BLAST of Tetraspanin vs. TrEMBL
Match: A0A1I8I7N5 (Tetraspanin OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 2.958e-13
Identity = 52/204 (25.49%), Postives = 105/204 (51.47%), Query Frame = 3 
Query:  396 KENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXF---NGILSTNS---SLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSH---PIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCA-TSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEVLCILFACYILRKDGK*QQN 977
            +E+ C+L  Y+  VS V++ +I  G+  GV + +    +  +LK +    +   N  +S +S   ++F+ +       M CCG++  +D T  +  W       N      P+ CCK+N+  +    S  N T +++++ D +C   +  +Q+N EGC   + + +    +A+I + I++ MFE++C++ AC +++K    +QN
Sbjct:   47 RESSCLLSIYAGAVSIVLIVEIAGGIAAGVFRAQIGTEMLPTLKRLEATRYLPINLAVSNDSNPNAVFSSLVNYAQVSMSCCGVSSMSDITGVNTLWTNSSRQYNGKTIVVPVTCCKMNKKDELL--SHQNWTRIDDYLIDRNCPYNASSSQINKEGCYDKLNSYIDRYTLAIIVVGILVGMFEIICVVMACSMVQKIRSERQN 248
[Close]
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: tspan3a (tetraspanin 3 [Source:NCBI gene;Acc:103046031])

HSP 1 Score: 48.521 bits (114), Expect = 3.797e-6
Identity = 35/140 (25.00%), Postives = 65/140 (46.43%), Query Frame = 3 
Query:  546 FNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEVLCILFACYILRKDGK 965
            +N    TNS   ++    +  Q+ CCGIT+  D+ +T  +W  +   +N S P+ CCK N                   +++ + + S+   L  EGC  +V+  +K  ++ VI   +     ++L +L AC +L + G+
Sbjct:  125 YNEYNGTNSDAPSRAIDYVQRQLHCCGITNYLDWRNT--SWFNE--SRNNSVPLSCCKPN-------------------VSNCTGSLSRPGDLYPEGCEALVVKKLKEIMMYVIWAALTFAAIQMLGMLCACVVLCRRGR 241
[Close]
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: tspan3a (tetraspanin 3 [Source:NCBI gene;Acc:103046031])

HSP 1 Score: 48.1358 bits (113), Expect = 4.067e-6
Identity = 35/140 (25.00%), Postives = 65/140 (46.43%), Query Frame = 3 
Query:  546 FNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEVLCILFACYILRKDGK 965
            +N    TNS   ++    +  Q+ CCGIT+  D+ +T  +W  +   +N S P+ CCK N                   +++ + + S+   L  EGC  +V+  +K  ++ VI   +     ++L +L AC +L + G+
Sbjct:   99 YNEYNGTNSDAPSRAIDYVQRQLHCCGITNYLDWRNT--SWFNE--SRNNSVPLSCCKPN-------------------VSNCTGSLSRPGDLYPEGCEALVVKKLKEIMMYVIWAALTFAAIQMLGMLCACVVLCRRGR 215
[Close]
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: tspan3a (tetraspanin 3 [Source:NCBI gene;Acc:103046031])

HSP 1 Score: 48.1358 bits (113), Expect = 4.875e-6
Identity = 35/140 (25.00%), Postives = 65/140 (46.43%), Query Frame = 3 
Query:  546 FNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEVLCILFACYILRKDGK 965
            +N    TNS   ++    +  Q+ CCGIT+  D+ +T  +W  +   +N S P+ CCK N                   +++ + + S+   L  EGC  +V+  +K  ++ VI   +     ++L +L AC +L + G+
Sbjct:  124 YNEYNGTNSDAPSRAIDYVQRQLHCCGITNYLDWRNT--SWFNE--SRNNSVPLSCCKPN-------------------VSNCTGSLSRPGDLYPEGCEALVVKKLKEIMMYVIWAALTFAAIQMLGMLCACVVLCRRGR 240
[Close]
BLAST of Tetraspanin vs. Ensembl Sea Lamprey
Match: cd82b (CD82 molecule b [Source:ZFIN;Acc:ZDB-GENE-030131-2857])

HSP 1 Score: 48.521 bits (114), Expect = 6.511e-7
Identity = 44/180 (24.44%), Postives = 83/180 (46.11%), Query Frame = 3 
Query:  396 KENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGILSTNSSLFT-KIFTSMMFQMKCCGITDETDFTDT----DQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEV 920
            KE +C+L  Y   +  +++AQ+ +G    + K K  N L      I+K  +N  LST   L T +++ S+  +  CCG+    D+ D     DQ     I     ++P  C   + + Q D N+        +F     C +S    +  +GC   + + +++N+  ++ +C+ + +FEV
Sbjct:   59 KEVRCLLAVYFICLVGLLVAQVAIGTVVYINKEKINNKLNGVAFNIIKSYWN--LSTEDPLHTWRLWDSIQQKFNCCGLNGTEDWKDNVYICDQATYPDI-----TYPCSCFNNSSSVQKDHNNT-------QF-----CISSPTFAIAEQGCEMHIKDWLQANMSVILAVCVAIAVFEV 219
[Close]
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000019443.1 (SMESG000019443.1)

HSP 1 Score: 238.039 bits (606), Expect = 6.373e-77
Identity = 125/258 (48.45%), Postives = 190/258 (73.64%), Query Frame = 3 
Query:  186 IIGSVFLIFGIWIKVNKNNLFKILRSVTLDDTVASFSNTSSSALDFVAXXXXXXXXXXXXXXXXXXXXSCKENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEVLCILFACYILRKD 959
            +IG++ L  GIW+K++K+NLF++LR++ L++T +SF NT+SS  D +A+ LI+LG   F+  FCGC G+ KE++C+L+ YS  V+ VI+ QI +G+Y GV+K K +  L+ SL  +L+ EFNGI+S N S+FTK  T++MF+MKCCGI +E DF  T QNW+Q I  +NQ HPIGCCK+ Q+F +D  +KLN TI+ + + DP C  ++ T+LN EGC+ V++  +++NL  VI +C+ L +FE+LCI+FAC + R++
Sbjct:   21 LIGALILGIGIWVKIDKSNLFEMLRNIKLEETASSFDNTNSSLFDTIAIFLIVLGAITFITGFCGCCGAIKESQCLLFLYSLFVTVVIVGQIGVGIYAGVQKNKVQYYLESSLVSVLENEFNGIISPNPSMFTKALTAIMFEMKCCGIRNENDFKITKQNWKQTIQGQNQVHPIGCCKIKQSFSFDSENKLNYTILSDILVDPLCPVTKATKLNYEGCISVLIEKIRNNLTIVISVCVGLGLFEMLCIVFACCVARRN 278
[Close]
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000078545.1 (SMESG000078545.1)

HSP 1 Score: 216.083 bits (549), Expect = 2.419e-68
Identity = 129/260 (49.62%), Postives = 185/260 (71.15%), Query Frame = 3 
Query:  186 IIGSVFLIFGIWIKVNKNNLFKILRSVTLDDTVASFSNTSSSALDFVAXXXXXXXXXXXXXXXXXXXXSCKENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATS---QKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEVLCILFACYILRK 956
            I+G VFL  GIW+KV+K+NLF+I+R V LD T +SF ++SSS L+ VA+ LI+LG   F+I FCGC G+ KEN C+LY YSFLV  VIL ++ +G+Y GVEKGKF+N + ++L  ILK EFNGI+S N+++FTK+FT++M ++KCCGI D+ DF  T  NWRQ I +K Q++PIGCC   + + Y+ N K  L  V+ F  +P C T+    + +LN  GC + +++L+  NL  VI +C+ L +FE+ CI+FAC ++ K
Sbjct:   21 ILGGVFLGVGIWVKVDKSNLFEIMRKVNLDGTASSFDSSSSSFLNIVAIVLIVLGTFTFIIGFCGCCGAIKENHCLLYLYSFLVGVVILIEVGIGIYAGVEKGKFKNGIDQALTKILKSEFNGIMSPNATIFTKVFTAVMLELKCCGIKDQEDFNSTKVNWRQIIDNKTQANPIGCCAEKEVYVYNTNDKFVLDKVKPFFKNPDCPTTTNRTQAKLNPTGCSQSLIDLINKNLGIVIGVCVGLGLFEIFCIIFACCVISK 280
[Close]
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000019444.1 (SMESG000019444.1)

HSP 1 Score: 207.608 bits (527), Expect = 3.494e-65
Identity = 122/245 (49.80%), Postives = 179/245 (73.06%), Query Frame = 3 
Query:  186 IIGSVFLIFGIWIKVNKNNLFKILRSVTLDDTVASFSNTSSSALDFVAXXXXXXXXXXXXXXXXXXXXSCKENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEV 920
            IIG+V L  GIW+KV+K+NLF+++R++ LD+T  SFS+T+SS  D VA+ LIILG   F+  FCGC G+ KE+ C+L+ YSFLV+ VI+AQ+ +G+Y  V++ KF+  L++SL  I+ K+FNG LS+N S+FTK+FT++MF+MKCCG+  E DF      W+Q I  + Q HPIGCCKL  +F ++   KLNLT+VE  + DP+C   ++T+LN +GC+  +++ +KS+L  VI +CI L +FEV
Sbjct:   21 IIGAVILGVGIWVKVDKSNLFEMMRNINLDETAKSFSSTNSSLFDIVAIILIILGAFTFITGFCGCCGAIKESSCLLFMYSFLVAAVIVAQVAVGIYASVQQNKFQARLEKSLIKIVAKDFNGALSSNPSMFTKVFTALMFEMKCCGVKGEADFNGIGDAWKQTISGRKQIHPIGCCKLKNSFHFNSKEKLNLTVVENTIEDPNCIFEKETKLNQKGCVVSLIDKIKSHLKIVIGVCIGLGLFEV 265
[Close]
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000078589.1 (SMESG000078589.1)

HSP 1 Score: 201.445 bits (511), Expect = 1.245e-62
Identity = 119/259 (45.95%), Postives = 175/259 (67.57%), Query Frame = 3 
Query:  186 IIGSVFLIFGIWIKVNKNNLFKILRSVTLDDTVASFSNTSSSALDFVAXXXXXXXXXXXXXXXXXXXXSCKENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCA--TSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEVLCILFACYILRK 956
            IIG+  L  GIW+KV+K+NLF+ILR + ++ +  SF NT ++ LD +A+ LI+ G   FV  FCGC G+ KEN+ +L TYS LV+  ++A+I +G+Y GVE+ KF N L +SLK ++KK+FNG  + N++ FTKIFT++MF ++CCGI DE+DF  T+ NW      K QSHP+GCCKLN   +Y+  S L    +++ +   +C   T+   +LN +GC+  ++ L+K NL  VI ICI L +FE+ CI FAC + R+
Sbjct:   21 IIGAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSILVAAAVIAEIGIGIYAGVEEKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWTIS-SGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKENLGIVIGICIGLGLFEIFCIAFACIVARR 278
[Close]
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000019444.1 (SMESG000019444.1)

HSP 1 Score: 209.149 bits (531), Expect = 2.252e-62
Identity = 123/245 (50.20%), Postives = 179/245 (73.06%), Query Frame = 3 
Query:  186 IIGSVFLIFGIWIKVNKNNLFKILRSVTLDDTVASFSNTSSSALDFVAXXXXXXXXXXXXXXXXXXXXSCKENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEV 920
            IIG+V L  GIW+KV+K+NLF+++R++ LD+T  SFS+T+SS  D VA+ LIILG   F+  FCGC G+ KE+ C+L+ YSFLV+ VI+AQ+ +G+Y  V++ KF+  L++SL  I+ K+FNG LS+N S+FTK+FT++MF+MKCCG+  E DF      W+Q I  + Q HPIGCCKL  +F ++   KLNLT+VE  M DP+C   ++T+LN +GC+  +++ +KS+L  VI +CI L +FEV
Sbjct:  334 IIGAVILGVGIWVKVDKSNLFEMMRNINLDETAKSFSSTNSSLFDIVAIILIILGAFTFITGFCGCCGAIKESSCLLFMYSFLVAAVIVAQVAVGIYASVQQNKFQARLEKSLIKIVAKDFNGALSSNPSMFTKVFTALMFEMKCCGVKGEADFNGIGDAWKQTINGRKQIHPIGCCKLKNSFHFNSKEKLNLTVVENTMEDPNCIFEKETKLNQKGCVVSLIDKIKSHLKIVIGVCIGLGLFEV 578

HSP 2 Score: 207.994 bits (528), Expect = 6.292e-62
Identity = 122/245 (49.80%), Postives = 179/245 (73.06%), Query Frame = 3 
Query:  186 IIGSVFLIFGIWIKVNKNNLFKILRSVTLDDTVASFSNTSSSALDFVAXXXXXXXXXXXXXXXXXXXXSCKENKCMLYTYSFLVSTVILAQICMGVYCGVEKGKFENXXXXXXXXXXXXXFNGILSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPIGCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATSQKTQLNTEGCLRVVLNLVKSNLVAVICICIVLCMFEV 920
            IIG+V L  GIW+KV+K+NLF+++R++ LD+T  SFS+T+SS  D VA+ LIILG   F+  FCGC G+ KE+ C+L+ YSFLV+ VI+AQ+ +G+Y  V++ KF+  L++SL  I+ K+FNG LS+N S+FTK+FT++MF+MKCCG+  E DF      W+Q I  + Q HPIGCCKL  +F ++   KLNLT+VE  + DP+C   ++T+LN +GC+  +++ +KS+L  VI +CI L +FEV
Sbjct:   21 IIGAVILGVGIWVKVDKSNLFEMMRNINLDETAKSFSSTNSSLFDIVAIILIILGAFTFITGFCGCCGAIKESSCLLFMYSFLVAAVIVAQVAVGIYASVQQNKFQARLEKSLIKIVAKDFNGALSSNPSMFTKVFTALMFEMKCCGVKGEADFNGIGDAWKQTISGRKQIHPIGCCKLKNSFHFNSKEKLNLTVVENTIEDPNCIFEKETKLNQKGCVVSLIDKIKSHLKIVIGVCIGLGLFEV 265
The following BLAST results are available for this feature:
BLAST of Tetraspanin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Tetraspanin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Tetraspanin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Tsp66E5.839e-723.23gene:FBgn0035936 transcript:FBtr0076507[more]
Tsp66E5.839e-723.23gene:FBgn0035936 transcript:FBtr0076506[more]
Tsp66E5.839e-723.23gene:FBgn0035936 transcript:FBtr0076508[more]
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BLAST of Tetraspanin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Tetraspanin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
gpr882.307e-622.58G protein-coupled receptor 88 [Source:Xenbase;Acc:... [more]
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BLAST of Tetraspanin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Tspan35.782e-727.57tetraspanin 3 [Source:MGI Symbol;Acc:MGI:1928098][more]
Tspan38.376e-727.57tetraspanin 3 [Source:MGI Symbol;Acc:MGI:1928098][more]
Tspan12.146e-623.24tetraspanin 1 [Source:MGI Symbol;Acc:MGI:1914055][more]
Tspan12.366e-623.24tetraspanin 1 [Source:MGI Symbol;Acc:MGI:1914055][more]
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BLAST of Tetraspanin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 2
Match NameE-valueIdentityDescription
sp|Q9QY33|TSN3_MOUSE4.045e-627.57Tetraspanin-3 OS=Mus musculus OX=10090 GN=Tspan3 P... [more]
sp|Q6AYR9|TSN1_RAT8.080e-625.20Tetraspanin-1 OS=Rattus norvegicus OX=10116 GN=Tsp... [more]
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BLAST of Tetraspanin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267EG052.836e-1526.37Tetraspanin OS=Macrostomum lignano OX=282301 GN=BO... [more]
A0A267FTC43.284e-1526.71Tetraspanin OS=Macrostomum lignano OX=282301 GN=BO... [more]
A0A267FNP29.552e-1526.86Tetraspanin OS=Macrostomum lignano OX=282301 GN=BO... [more]
A0A1I8H8362.872e-1325.00Tetraspanin OS=Macrostomum lignano OX=282301 PE=3 ... [more]
A0A1I8I7N52.958e-1325.49Tetraspanin OS=Macrostomum lignano OX=282301 PE=3 ... [more]
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BLAST of Tetraspanin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
tspan3a3.797e-625.00tetraspanin 3 [Source:NCBI gene;Acc:103046031][more]
tspan3a4.067e-625.00tetraspanin 3 [Source:NCBI gene;Acc:103046031][more]
tspan3a4.875e-625.00tetraspanin 3 [Source:NCBI gene;Acc:103046031][more]
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BLAST of Tetraspanin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
cd82b6.511e-724.44CD82 molecule b [Source:ZFIN;Acc:ZDB-GENE-030131-2... [more]
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BLAST of Tetraspanin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Tetraspanin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Tetraspanin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Tetraspanin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000019443.16.373e-7748.45SMESG000019443.1[more]
SMESG000078545.12.419e-6849.62SMESG000078545.1[more]
SMESG000019444.13.494e-6549.80SMESG000019444.1[more]
SMESG000078589.11.245e-6245.95SMESG000078589.1[more]
SMESG000019444.12.252e-6250.20SMESG000019444.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011329 ID=SMED30011329|Name=Tetraspanin|organism=Schmidtea mediterranea sexual|type=transcript|length=1044bp
GTACTTTTTACACCAAGTTCATCTCATTGTACGCATTTCTTGACTGGTTT
ATGAGTGTGCATTTTAAATTCATTCACTAATCTGCTCTTGATTATTGATA
AACATTTATGATAGGGTGCCGAGCTCACACATTCAAATTGATCTTGCGTA
TTGGGATGAAAAGATTCTTGAAAATAAAGATAATGATAATCGGATCAGTT
TTTTTGATTTTCGGGATATGGATCAAAGTAAACAAAAACAATCTATTCAA
AATCCTGAGAAGTGTTACCCTCGATGACACTGTGGCCTCATTCTCGAATA
CGAGCTCATCAGCTTTGGATTTTGTGGCACTCGGATTAATAATTCTGGGA
GGGTGCATATTTGTAATTTGTTTTTGCGGTTGTTTTGGCAGCTGCAAAGA
AAATAAATGCATGTTGTATACTTATTCATTTCTGGTTAGCACTGTGATTT
TAGCTCAGATCTGCATGGGAGTTTACTGTGGGGTTGAAAAAGGCAAATTT
GAAAATTTACTGAAAGAAAGTTTGAAAATTATTTTAAAGAAAGAATTTAA
CGGAATATTATCCACTAATTCGTCTTTGTTCACGAAAATCTTTACATCGA
TGATGTTCCAGATGAAATGTTGTGGAATAACAGATGAAACAGATTTCACA
GACACTGACCAAAATTGGCGGCAAAAAATAGTAGATAAAAATCAAAGCCA
TCCGATTGGTTGCTGCAAATTAAACCAAACATTTCAATACGACCCAAATT
CAAAATTAAATCTTACAATTGTGGAAGAATTTATGGCGGATCCCTCATGC
GCAACTAGTCAAAAAACACAATTAAATACCGAAGGTTGCTTGCGGGTTGT
ATTAAACTTGGTTAAAAGTAATTTGGTTGCCGTTATCTGCATCTGCATCG
TATTGTGTATGTTTGAGGTACTTTGCATATTATTCGCGTGTTACATTTTA
CGGAAAGACGGAAAATAGCAACAAAACAAAATCATTTACTTATCAATTTT
TCCATTGAAATTATTCGCAATTTTACGCAAAAATTACAATTAAG
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protein sequence of SMED30011329-orf-1

>SMED30011329-orf-1 ID=SMED30011329-orf-1|Name=SMED30011329-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=287bp
MIGCRAHTFKLILRIGMKRFLKIKIMIIGSVFLIFGIWIKVNKNNLFKIL
RSVTLDDTVASFSNTSSSALDFVALGLIILGGCIFVICFCGCFGSCKENK
CMLYTYSFLVSTVILAQICMGVYCGVEKGKFENLLKESLKIILKKEFNGI
LSTNSSLFTKIFTSMMFQMKCCGITDETDFTDTDQNWRQKIVDKNQSHPI
GCCKLNQTFQYDPNSKLNLTIVEEFMADPSCATSQKTQLNTEGCLRVVLN
LVKSNLVAVICICIVLCMFEVLCILFACYILRKDGK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
Vocabulary: INTERPRO
TermDefinition
IPR000301Tetraspanin
IPR018499Tetraspanin/Peripherin
IPR008952Tetraspanin_EC2_sf
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000301TetraspaninPRINTSPR00259TMFOURcoord: 233..259
score: 17.65
coord: 45..71
score: 28.84
coord: 72..100
score: 24.21
IPR000301TetraspaninPIRSFPIRSF002419Tetraspanincoord: 1..261
e-value: 2.0E-28
score: 96.8
IPR018499Tetraspanin/PeripherinPFAMPF00335Tetraspanincoord: 1..257
e-value: 4.7E-34
score: 118.1
NoneNo IPR availablePANTHERPTHR19282:SF263LEUKOCYTE ANTIGEN CD37coord: 1..249
NoneNo IPR availablePANTHERPTHR19282TETRASPANINcoord: 1..249
NoneNo IPR availableTMHMMTMhelixcoord: 47..69
NoneNo IPR availableTMHMMTMhelixcoord: 78..100
NoneNo IPR availableTMHMMTMhelixcoord: 231..253
IPR008952Tetraspanin, EC2 domain superfamilySUPERFAMILYSSF48652Tetraspanincoord: 108..231