PHD-type domain-containing protein

Overview
NamePHD-type domain-containing protein
Smed IDSMED30011300
Length (bp)3333
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of PHD-type domain-containing protein (SMED30011300) t-SNE clustered cells

Violin plots show distribution of expression levels for PHD-type domain-containing protein (SMED30011300) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of PHD-type domain-containing protein (SMED30011300) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for PHD-type domain-containing protein (SMED30011300) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30011300

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30011300h1SMcG0000792 dd_Smed_v4_3984_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30011300h1SMcG0000792 dd_Smed_v4_3984_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30011300h1SMcG0000792 dd_Smed_v4_3984_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30011300h1SMcG0000792 dd_Smed_v4_3984_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30011300h1SMcG0000792 dd_Smed_v4_3984_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30011300h1SMcG0000792 dd_Smed_v4_3984_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30011300h1SMcG0000792 Contig48573newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30011300h1SMcG0000792 Contig48573uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of PHD-type domain-containing protein vs. Ensembl Human
Match: RSF1 (remodeling and spacing factor 1 [Source:HGNC Symbol;Acc:HGNC:18118])

HSP 1 Score: 112.079 bits (279), Expect = 1.464e-26
Identity = 48/91 (52.75%), Postives = 64/91 (70.33%), Query Frame = 2
Query: 1616 KPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNIL 1888
            +PC+ C   N PE+ILLCD CD G+H  CL+P LMIIP+GEWFCP CQHK L  KL E++ +L+ ++ K     R +ERL +V IS+ NI+
Sbjct:    1 EPCKKCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCEKLEEQLQDLDVALKKKERAERRKERLVYVGISIENII 91          
BLAST of PHD-type domain-containing protein vs. Ensembl Human
Match: RSF1 (remodeling and spacing factor 1 [Source:HGNC Symbol;Acc:HGNC:18118])

HSP 1 Score: 119.398 bits (298), Expect = 1.873e-26
Identity = 50/93 (53.76%), Postives = 66/93 (70.97%), Query Frame = 2
Query: 1610 DDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNIL 1888
            DD+PC+ C   N PE+ILLCD CD G+H  CL+P LMIIP+GEWFCP CQHK L  KL E++ +L+ ++ K     R +ERL +V IS+ NI+
Sbjct:  638 DDEPCKKCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCEKLEEQLQDLDVALKKKERAERRKERLVYVGISIENII 730          
BLAST of PHD-type domain-containing protein vs. Ensembl Human
Match: RSF1 (remodeling and spacing factor 1 [Source:HGNC Symbol;Acc:HGNC:18118])

HSP 1 Score: 118.242 bits (295), Expect = 2.521e-26
Identity = 50/93 (53.76%), Postives = 66/93 (70.97%), Query Frame = 2
Query: 1610 DDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNIL 1888
            DD+PC+ C   N PE+ILLCD CD G+H  CL+P LMIIP+GEWFCP CQHK L  KL E++ +L+ ++ K     R +ERL +V IS+ NI+
Sbjct:  691 DDEPCKKCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCEKLEEQLQDLDVALKKKERAERRKERLVYVGISIENII 783          
BLAST of PHD-type domain-containing protein vs. Ensembl Human
Match: RSF1 (remodeling and spacing factor 1 [Source:HGNC Symbol;Acc:HGNC:18118])

HSP 1 Score: 118.242 bits (295), Expect = 4.894e-26
Identity = 50/93 (53.76%), Postives = 66/93 (70.97%), Query Frame = 2
Query: 1610 DDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNIL 1888
            DD+PC+ C   N PE+ILLCD CD G+H  CL+P LMIIP+GEWFCP CQHK L  KL E++ +L+ ++ K     R +ERL +V IS+ NI+
Sbjct:  890 DDEPCKKCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCEKLEEQLQDLDVALKKKERAERRKERLVYVGISIENII 982          

HSP 2 Score: 90.1225 bits (222), Expect = 1.704e-17
Identity = 56/186 (30.11%), Postives = 96/186 (51.61%), Query Frame = 2
Query:   86 PEFASLCSFIQLFGEELNVT-LSHCQLSKFLEITDAD----NVPKIWIDIHRRLLSRIKYRCSIDKWEGTLKKCLVNVLG-YESELA-NLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMYKENLEEE---SFKIVAESLEDLNNIL 613
            P FA +CSF++ +G  L++  L   +L + L+    D     VPK  +++H +L+ +I    + D+WE    K L+ +   + S  A  +    Y  +S E +  +L  L +CQFD N+KFK  +N +    +R QP G D  G +YW  +D D ++ MY E  +++   S+K +  +  +L   L
Sbjct:   21 PNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWE----KYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKYLCECQFDDNLKFKNIINEEDADTMRLQPIGRDKDGLMYWYQLDQDHNVRMYIEEQDDQDGSSWKCIVRNRNELAETL 202          
BLAST of PHD-type domain-containing protein vs. Ensembl Human
Match: RSF1 (remodeling and spacing factor 1 [Source:HGNC Symbol;Acc:HGNC:18118])

HSP 1 Score: 89.3521 bits (220), Expect = 1.974e-17
Identity = 52/161 (32.30%), Postives = 83/161 (51.55%), Query Frame = 2
Query:   86 PEFASLCSFIQLFGEELNVT-LSHCQLSKFLEITDAD----NVPKIWIDIHRRLLSRIKYRCSIDKWEGTLKKCLVNVLGYESELA-NLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMYKE 550
            P FA +CSF++ +G  L++  L   +L + L+    D     VPK  +++H +L+ +I    + D+WE  L K       + S  A  +    Y  +S E +  +L  L +CQFD N+KFK  +N +    +R QP G D  G +YW  +D D ++ MY E
Sbjct:   20 PNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQE---FNSTWAWEMEKKGYLEMSVECKLALLKYLCECQFDDNLKFKNIINEEDADTMRLQPIGRDKDGLMYWYQLDQDHNVRMYIE 177          
BLAST of PHD-type domain-containing protein vs. Ensembl Celegans
Match: chd-3 (Chromodomain-helicase-DNA-binding protein 3 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q22516])

HSP 1 Score: 55.0694 bits (131), Expect = 3.380e-7
Identity = 23/45 (51.11%), Postives = 29/45 (64.44%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKC 1756
            C+IC + +    ILLCD C   +HA C+ P L  IPEGEW CP+C
Sbjct:  331 CRICKETS---NILLCDTCPSSYHAYCIDPPLTEIPEGEWSCPRC 372          
BLAST of PHD-type domain-containing protein vs. Ensembl Celegans
Match: baz-2 (Bromodomain Adjacent to Zinc finger domain, 2A/2B, homolog [Source:UniProtKB/TrEMBL;Acc:Q23590])

HSP 1 Score: 54.6842 bits (130), Expect = 5.257e-7
Identity = 22/49 (44.90%), Postives = 32/49 (65.31%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKK 1768
            CQIC   +  EM L+CD C+ G H  C +P +  +PEG+WFC +C+ +K
Sbjct: 1103 CQICKSMDGDEM-LVCDGCESGCHMECFRPRMTKVPEGDWFCQRCREEK 1150          
BLAST of PHD-type domain-containing protein vs. Ensembl Celegans
Match: dpff-1 (Zinc finger protein dpff-1 [Source:UniProtKB/Swiss-Prot;Acc:Q09477])

HSP 1 Score: 49.6766 bits (117), Expect = 8.811e-6
Identity = 21/48 (43.75%), Postives = 28/48 (58.33%), Query Frame = 2
Query: 1616 KPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQ 1759
            K C IC  +   + +L CDDCD G+H  CL P+L   P+ E+ C  CQ
Sbjct:  312 KSCTICGTSENDDKLLFCDDCDRGYHLYCLTPALEKAPDDEYSCRLCQ 359          
BLAST of PHD-type domain-containing protein vs. Ensembl Fly
Match: CG8677 (gene:FBgn0026577 transcript:FBtr0331677)

HSP 1 Score: 90.8929 bits (224), Expect = 5.404e-18
Identity = 58/183 (31.69%), Postives = 105/183 (57.38%), Query Frame = 2
Query:   86 PEFASLCSFIQLFGEELNVTLSHCQ-LSKFLEITDADNVPKIWIDIHRRLLSRIKYRCSIDKWEGTLKK-CLVNVLGYESELA-NLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISD-LRTQPFGSDIHGCIYWLFVDIDISIIMYKENLEEESFKIVAESLEDLNNILKEL 622
            P+FA +C+F+Q FG++L + L + + L ++L  T+ ++VP++  D+H +LL + +       WE  L K C     GY  + A  +    Y   S + + +I   L + QF++N KF+  + L L +D LR++P G D  G  YWL  D   ++ +Y+E+L+EE +++VA + ++  N++  L
Sbjct:   43 PDFAVICAFLQKFGKDLGLNLPNFKHLQEWL--TNNNDVPELR-DLHIKLLRKTRKTVHEKSWESALSKFCF----GYSVQDAWEIERFGYRNSSLKVKLRIFRELLESQFERNAKFRAHI-LTLNADTLRSEPIGRDRLGHAYWLTQDAHCNLRIYQEHLDEEIWQVVATNRDEFVNLISRL 217          

HSP 2 Score: 72.7886 bits (177), Expect = 2.002e-12
Identity = 33/80 (41.25%), Postives = 48/80 (60.00%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDD--CDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERL 1855
            CQ C K++ PE ILLCD   C+ G+H  CL P L  IPEG+W CP CQ ++LI  L  ++ + +  + +     + QER+
Sbjct: 1373 CQKCGKSDHPEWILLCDTPTCNKGYHCSCLSPVLFYIPEGDWHCPPCQQEQLIAALERQLEQYDTLVAQ-----KQQERI 1447          
BLAST of PHD-type domain-containing protein vs. Ensembl Fly
Match: CG8677 (gene:FBgn0026577 transcript:FBtr0346586)

HSP 1 Score: 90.8929 bits (224), Expect = 5.404e-18
Identity = 58/183 (31.69%), Postives = 105/183 (57.38%), Query Frame = 2
Query:   86 PEFASLCSFIQLFGEELNVTLSHCQ-LSKFLEITDADNVPKIWIDIHRRLLSRIKYRCSIDKWEGTLKK-CLVNVLGYESELA-NLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISD-LRTQPFGSDIHGCIYWLFVDIDISIIMYKENLEEESFKIVAESLEDLNNILKEL 622
            P+FA +C+F+Q FG++L + L + + L ++L  T+ ++VP++  D+H +LL + +       WE  L K C     GY  + A  +    Y   S + + +I   L + QF++N KF+  + L L +D LR++P G D  G  YWL  D   ++ +Y+E+L+EE +++VA + ++  N++  L
Sbjct:   43 PDFAVICAFLQKFGKDLGLNLPNFKHLQEWL--TNNNDVPELR-DLHIKLLRKTRKTVHEKSWESALSKFCF----GYSVQDAWEIERFGYRNSSLKVKLRIFRELLESQFERNAKFRAHI-LTLNADTLRSEPIGRDRLGHAYWLTQDAHCNLRIYQEHLDEEIWQVVATNRDEFVNLISRL 217          

HSP 2 Score: 72.7886 bits (177), Expect = 2.002e-12
Identity = 33/80 (41.25%), Postives = 48/80 (60.00%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDD--CDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERL 1855
            CQ C K++ PE ILLCD   C+ G+H  CL P L  IPEG+W CP CQ ++LI  L  ++ + +  + +     + QER+
Sbjct: 1373 CQKCGKSDHPEWILLCDTPTCNKGYHCSCLSPVLFYIPEGDWHCPPCQQEQLIAALERQLEQYDTLVAQ-----KQQERI 1447          
BLAST of PHD-type domain-containing protein vs. Ensembl Fly
Match: lid (gene:FBgn0031759 transcript:FBtr0079231)

HSP 1 Score: 64.6994 bits (156), Expect = 6.121e-10
Identity = 23/45 (51.11%), Postives = 30/45 (66.67%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKC 1756
            C IC + ++ E +LLCD CD  +H  CL P L  IP+GEW CP+C
Sbjct:  451 CHICNRGDVEESMLLCDGCDDSYHTFCLLPPLTSIPKGEWLCPRC 495          
BLAST of PHD-type domain-containing protein vs. Ensembl Fly
Match: lid (gene:FBgn0031759 transcript:FBtr0079232)

HSP 1 Score: 64.6994 bits (156), Expect = 6.121e-10
Identity = 23/45 (51.11%), Postives = 30/45 (66.67%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKC 1756
            C IC + ++ E +LLCD CD  +H  CL P L  IP+GEW CP+C
Sbjct:  451 CHICNRGDVEESMLLCDGCDDSYHTFCLLPPLTSIPKGEWLCPRC 495          
BLAST of PHD-type domain-containing protein vs. Ensembl Fly
Match: lid (gene:FBgn0031759 transcript:FBtr0307070)

HSP 1 Score: 64.6994 bits (156), Expect = 6.121e-10
Identity = 23/45 (51.11%), Postives = 30/45 (66.67%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKC 1756
            C IC + ++ E +LLCD CD  +H  CL P L  IP+GEW CP+C
Sbjct:  451 CHICNRGDVEESMLLCDGCDDSYHTFCLLPPLTSIPKGEWLCPRC 495          
BLAST of PHD-type domain-containing protein vs. Ensembl Zebrafish
Match: rsf1b.1 (remodeling and spacing factor 1b, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-030131-5829])

HSP 1 Score: 118.627 bits (296), Expect = 9.119e-27
Identity = 49/96 (51.04%), Postives = 67/96 (69.79%), Query Frame = 2
Query: 1610 DDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNILSKS 1897
            +D PC+ C   N PE+ILLCD CD G+H  CL+P LMIIP+GEWFCP CQHK L ++L E++  L+ ++ K     R +ERL +V IS+ NI++ S
Sbjct:  164 NDDPCKHCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCDRLEEQLLNLDAALKKKERAERRKERLVYVGISVENIITPS 259          
BLAST of PHD-type domain-containing protein vs. Ensembl Zebrafish
Match: rsf1b.1 (remodeling and spacing factor 1b, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-030131-5829])

HSP 1 Score: 117.087 bits (292), Expect = 6.737e-26
Identity = 49/96 (51.04%), Postives = 67/96 (69.79%), Query Frame = 2
Query: 1610 DDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNILSKS 1897
            +D PC+ C   N PE+ILLCD CD G+H  CL+P LMIIP+GEWFCP CQHK L ++L E++  L+ ++ K     R +ERL +V IS+ NI++ S
Sbjct: 1368 NDDPCKHCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCDRLEEQLLNLDAALKKKERAERRKERLVYVGISVENIITPS 1463          

HSP 2 Score: 102.834 bits (255), Expect = 1.651e-21
Identity = 72/237 (30.38%), Postives = 124/237 (52.32%), Query Frame = 2
Query:   86 PEFASLCSFIQLFGEELNVT-LSHCQLSKFLEITDADNVPKIWIDIHRRLLSRIKYRCSIDKWEGTLKKC---LVNVLGYESELANLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMY---KENLEEESFKIVAESLEDLNNILKEL-SEVDCE---KVNLSQLYSVNSPS-DDVDHSRNQSPILDNISGILEKATNK 760
            P FA +CSF++ +G  L++  +S  +L + L+  D+  VPK+ +D+H +LL +I    S ++WE  L K          +E     L    Y  ++ E +  IL  L +CQFD N+KFK  +N +    +R QP G D  G +YW  +D D ++ +Y   +++L+  S+K +  + +DL  IL  L +++D     K    +  S NSP+ DD ++ + +   ++     L K+ NK
Sbjct:   16 PSFAVICSFLERYGALLDLPEVSFPELERSLQ--DSSAVPKLLVDLHVKLLRKIGKSVSAERWEKYLIKICQEFNTTWAWE-----LEKKGYQELTVECKTGILKYLCECQFDDNVKFKNAINEEDPDKMRLQPIGRDKDGLMYWFQLDQDHNVRIYVEEQDDLDGSSWKCIVRNRDDLAQILGLLKTQIDPALLVKKEQEEGSSNNSPNPDDEENKKKEGAEVEKSQDDLSKSENK 245          
BLAST of PHD-type domain-containing protein vs. Ensembl Zebrafish
Match: rsf1b.1 (remodeling and spacing factor 1b, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-030131-5829])

HSP 1 Score: 100.908 bits (250), Expect = 1.684e-21
Identity = 72/237 (30.38%), Postives = 124/237 (52.32%), Query Frame = 2
Query:   86 PEFASLCSFIQLFGEELNVT-LSHCQLSKFLEITDADNVPKIWIDIHRRLLSRIKYRCSIDKWEGTLKKC---LVNVLGYESELANLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMY---KENLEEESFKIVAESLEDLNNILKEL-SEVDCE---KVNLSQLYSVNSPS-DDVDHSRNQSPILDNISGILEKATNK 760
            P FA +CSF++ +G  L++  +S  +L + L+  D+  VPK+ +D+H +LL +I    S ++WE  L K          +E     L    Y  ++ E +  IL  L +CQFD N+KFK  +N +    +R QP G D  G +YW  +D D ++ +Y   +++L+  S+K +  + +DL  IL  L +++D     K    +  S NSP+ DD ++ + +   ++     L K+ NK
Sbjct:   16 PSFAVICSFLERYGALLDLPEVSFPELERSLQ--DSSAVPKLLVDLHVKLLRKIGKSVSAERWEKYLIKICQEFNTTWAWE-----LEKKGYQELTVECKTGILKYLCECQFDDNVKFKNAINEEDPDKMRLQPIGRDKDGLMYWFQLDQDHNVRIYVEEQDDLDGSSWKCIVRNRDDLAQILGLLKTQIDPALLVKKEQEEGSSNNSPNPDDEENKKKEGAEVEKSQDDLSKSENK 245          
BLAST of PHD-type domain-containing protein vs. Ensembl Zebrafish
Match: baz2a (bromodomain adjacent to zinc finger domain, 2A [Source:ZFIN;Acc:ZDB-GENE-041010-202])

HSP 1 Score: 68.9366 bits (167), Expect = 3.665e-11
Identity = 25/49 (51.02%), Postives = 34/49 (69.39%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKK 1768
            CQ+C K +  E +LLCD CD G H  CL+P ++ +P+G+WFCP C  KK
Sbjct: 2236 CQVCRKGDDDEYLLLCDGCDRGCHMFCLRPKVLQVPDGDWFCPNCVAKK 2284          
BLAST of PHD-type domain-containing protein vs. Ensembl Zebrafish
Match: baz2ba (bromodomain adjacent to zinc finger domain, 2Ba [Source:ZFIN;Acc:ZDB-GENE-070615-37])

HSP 1 Score: 65.4698 bits (158), Expect = 1.811e-10
Identity = 25/48 (52.08%), Postives = 32/48 (66.67%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHK 1765
            CQIC K +  +++LLCD CD G H  C KP +  IPEG+W+CP C  K
Sbjct:  199 CQICRKGDNEDLLLLCDGCDKGCHTYCHKPKITTIPEGDWYCPDCISK 246          
BLAST of PHD-type domain-containing protein vs. Ensembl Xenopus
Match: soat2 (sterol O-acyltransferase 2 [Source:Xenbase;Acc:XB-GENE-961303])

HSP 1 Score: 116.316 bits (290), Expect = 1.583e-25
Identity = 49/93 (52.69%), Postives = 64/93 (68.82%), Query Frame = 2
Query: 1610 DDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNIL 1888
            DD+PC+ C   N PE+ILLCD CD G+H  CL+P LM+IP+GEWFCP CQHK L  KL E++  L+  + K     R +ERL +V IS+ NI+
Sbjct:  810 DDEPCKKCGLPNHPELILLCDSCDSGYHTACLRPPLMLIPDGEWFCPPCQHKLLCEKLDEQLQNLDVVLKKKERAERRKERLVYVGISLENII 902          

HSP 2 Score: 63.5438 bits (153), Expect = 2.231e-9
Identity = 53/195 (27.18%), Postives = 91/195 (46.67%), Query Frame = 2
Query:  344 NYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMYKENLEEE---SFKIVAESLEDLNNILKEL-SEVD---CEKVNLSQLYSVNSPSDDVDHSRNQSPILDNISGILEKATNKLIPTKMETNDLSVDIKNEGIDTEIDYSTNEPILDDIQPKSEEILKIETE 907
             Y  +S E +  IL  L +CQFD N+KFK  +N +    +R QP G D  G +YW  +D D +I MY E  +++   ++K +  +  +L   L+ L +++D    +K    +  S  SP+ + D ++ Q     N  G  E    K      ++     + K E     +     +PI   +Q K+E +  +ET+
Sbjct:    5 GYQEMSVECKVGILKHLCECQFDDNLKFKNAINEEEADAMRLQPIGRDKDGLMYWFQLDQDHNIRMYIEEQDDQDGSTWKCIVRTRNELAETLELLKAQIDPALLKKSEPQESSSRESPNPEEDETKKQ-----NGEGAPEDGAIKEEKPDEKSQQSPSNCKEEDQSNGLITEDGQPIKSSLQIKTEPVSDMETD 194          
BLAST of PHD-type domain-containing protein vs. Ensembl Xenopus
Match: soat2 (sterol O-acyltransferase 2 [Source:Xenbase;Acc:XB-GENE-961303])

HSP 1 Score: 115.931 bits (289), Expect = 1.871e-25
Identity = 49/93 (52.69%), Postives = 64/93 (68.82%), Query Frame = 2
Query: 1610 DDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNIL 1888
            DD+PC+ C   N PE+ILLCD CD G+H  CL+P LM+IP+GEWFCP CQHK L  KL E++  L+  + K     R +ERL +V IS+ NI+
Sbjct:  868 DDEPCKKCGLPNHPELILLCDSCDSGYHTACLRPPLMLIPDGEWFCPPCQHKLLCEKLDEQLQNLDVVLKKKERAERRKERLVYVGISLENII 960          

HSP 2 Score: 77.7962 bits (190), Expect = 8.820e-14
Identity = 67/244 (27.46%), Postives = 115/244 (47.13%), Query Frame = 2
Query:  203 KIWIDIHRRLLSRIKYRCSIDKWEGTLKKCLVNVLG-YESELA-NLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMYKENLEEE---SFKIVAESLEDLNNILKEL-SEVD---CEKVNLSQLYSVNSPSDDVDHSRNQSPILDNISGILEKATNKLIPTKMETNDLSVDIKNEGIDTEIDYSTNEPILDDIQPKSEEILKIETE 907
            K  +++H +LL +I    ++D+WE    K L+ V   Y S  A  +    Y  +S E +  IL  L +CQFD N+KFK  +N +    +R QP G D  G +YW  +D D +I MY E  +++   ++K +  +  +L   L+ L +++D    +K    +  S  SP+ + D ++ Q     N  G  E    K      ++     + K E     +     +PI   +Q K+E +  +ET+
Sbjct:   18 KPLVELHLKLLRKIGKSVTVDRWE----KYLIKVCQEYNSTWAWEMEKKGYQEMSVECKVGILKHLCECQFDDNLKFKNAINEEEADAMRLQPIGRDKDGLMYWFQLDQDHNIRMYIEEQDDQDGSTWKCIVRTRNELAETLELLKAQIDPALLKKSEPQESSSRESPNPEEDETKKQ-----NGEGAPEDGAIKEEKPDEKSQQSPSNCKEEDQSNGLITEDGQPIKSSLQIKTEPVSDMETD 252          
BLAST of PHD-type domain-containing protein vs. Ensembl Xenopus
Match: BAZ1A (bromodomain adjacent to zinc finger domain 1A [Source:NCBI gene;Acc:100497377])

HSP 1 Score: 69.707 bits (169), Expect = 3.168e-11
Identity = 25/57 (43.86%), Postives = 37/57 (64.91%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEK 1792
            C++C K    E ++LCD CD GHH  C++P L  +PEG+WFCP+C  K+   +L  +
Sbjct: 1164 CKVCRKKGDGESMVLCDGCDRGHHIYCVRPKLKYVPEGDWFCPECHPKQRSRRLPSR 1220          
BLAST of PHD-type domain-containing protein vs. Ensembl Xenopus
Match: BAZ1A (bromodomain adjacent to zinc finger domain 1A [Source:NCBI gene;Acc:100497377])

HSP 1 Score: 69.3218 bits (168), Expect = 3.350e-11
Identity = 25/57 (43.86%), Postives = 37/57 (64.91%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEK 1792
            C++C K    E ++LCD CD GHH  C++P L  +PEG+WFCP+C  K+   +L  +
Sbjct: 1002 CKVCRKKGDGESMVLCDGCDRGHHIYCVRPKLKYVPEGDWFCPECHPKQRSRRLPSR 1058          
BLAST of PHD-type domain-containing protein vs. Ensembl Xenopus
Match: BAZ1A (bromodomain adjacent to zinc finger domain 1A [Source:NCBI gene;Acc:100497377])

HSP 1 Score: 69.3218 bits (168), Expect = 3.445e-11
Identity = 25/57 (43.86%), Postives = 37/57 (64.91%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEK 1792
            C++C K    E ++LCD CD GHH  C++P L  +PEG+WFCP+C  K+   +L  +
Sbjct: 1164 CKVCRKKGDGESMVLCDGCDRGHHIYCVRPKLKYVPEGDWFCPECHPKQRSRRLPSR 1220          
BLAST of PHD-type domain-containing protein vs. Ensembl Mouse
Match: Rsf1 (remodeling and spacing factor 1 [Source:MGI Symbol;Acc:MGI:2682305])

HSP 1 Score: 118.242 bits (295), Expect = 3.476e-26
Identity = 50/93 (53.76%), Postives = 66/93 (70.97%), Query Frame = 2
Query: 1610 DDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNIL 1888
            DD+PC+ C   N PE+ILLCD CD G+H  CL+P LMIIP+GEWFCP CQHK L  KL E++ +L+ ++ K     R +ERL +V IS+ NI+
Sbjct:  893 DDEPCKKCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCEKLEEQLQDLDVALKKKERAERRKERLVYVGISIENII 985          

HSP 2 Score: 89.7373 bits (221), Expect = 1.757e-17
Identity = 56/186 (30.11%), Postives = 96/186 (51.61%), Query Frame = 2
Query:   86 PEFASLCSFIQLFGEELNVT-LSHCQLSKFLEITDAD----NVPKIWIDIHRRLLSRIKYRCSIDKWEGTLKKCLVNVLG-YESELA-NLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMYKENLEEE---SFKIVAESLEDLNNIL 613
            P FA +CSF++ +G  L++  L   +L + L+    D     VPK  +++H +L+ +I    + D+WE    K L+ +   + S  A  +    Y  +S E +  +L  L +CQFD N+KFK  +N +    +R QP G D  G +YW  +D D ++ MY E  +++   S+K +  +  +L   L
Sbjct:   26 PNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDIGNGEVPKELVELHLKLMRKIGKSVTADRWE----KYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKYLCECQFDDNLKFKNIINEEDADTMRLQPIGRDKDGLMYWYQLDQDHNVRMYIEEQDDQDGSSWKCIVRNRNELAETL 207          
BLAST of PHD-type domain-containing protein vs. Ensembl Mouse
Match: Baz1a (bromodomain adjacent to zinc finger domain 1A [Source:MGI Symbol;Acc:MGI:1309478])

HSP 1 Score: 68.5514 bits (166), Expect = 4.672e-11
Identity = 24/48 (50.00%), Postives = 34/48 (70.83%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHK 1765
            C+IC K    E ++LCD CD GHH  C++P L  +P+G+WFCP+C+ K
Sbjct: 1152 CKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKAVPDGDWFCPECRPK 1199          
BLAST of PHD-type domain-containing protein vs. Ensembl Mouse
Match: Baz1a (bromodomain adjacent to zinc finger domain 1A [Source:MGI Symbol;Acc:MGI:1309478])

HSP 1 Score: 68.5514 bits (166), Expect = 4.790e-11
Identity = 24/48 (50.00%), Postives = 34/48 (70.83%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHK 1765
            C+IC K    E ++LCD CD GHH  C++P L  +P+G+WFCP+C+ K
Sbjct: 1149 CKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKAVPDGDWFCPECRPK 1196          
BLAST of PHD-type domain-containing protein vs. Ensembl Mouse
Match: Baz2b (bromodomain adjacent to zinc finger domain, 2B [Source:MGI Symbol;Acc:MGI:2442782])

HSP 1 Score: 68.5514 bits (166), Expect = 5.476e-11
Identity = 30/68 (44.12%), Postives = 42/68 (61.76%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKN 1825
            CQIC K +  E++LLCD CD G H  C +P +  IP+G+WFCP C     I+K S +  +++K  VK 
Sbjct: 1889 CQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPAC-----ISKASGQSIKIKKIHVKG 1951          
BLAST of PHD-type domain-containing protein vs. Ensembl Mouse
Match: Baz2b (bromodomain adjacent to zinc finger domain, 2B [Source:MGI Symbol;Acc:MGI:2442782])

HSP 1 Score: 68.5514 bits (166), Expect = 5.476e-11
Identity = 30/68 (44.12%), Postives = 42/68 (61.76%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKN 1825
            CQIC K +  E++LLCD CD G H  C +P +  IP+G+WFCP C     I+K S +  +++K  VK 
Sbjct: 1889 CQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPAC-----ISKASGQSIKIKKIHVKG 1951          
BLAST of PHD-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q96T23|RSF1_HUMAN (Remodeling and spacing factor 1 OS=Homo sapiens OX=9606 GN=RSF1 PE=1 SV=2)

HSP 1 Score: 118.242 bits (295), Expect = 2.350e-25
Identity = 50/93 (53.76%), Postives = 66/93 (70.97%), Query Frame = 2
Query: 1610 DDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNIL 1888
            DD+PC+ C   N PE+ILLCD CD G+H  CL+P LMIIP+GEWFCP CQHK L  KL E++ +L+ ++ K     R +ERL +V IS+ NI+
Sbjct:  890 DDEPCKKCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCEKLEEQLQDLDVALKKKERAERRKERLVYVGISIENII 982          

HSP 2 Score: 90.1225 bits (222), Expect = 8.182e-17
Identity = 56/186 (30.11%), Postives = 96/186 (51.61%), Query Frame = 2
Query:   86 PEFASLCSFIQLFGEELNVT-LSHCQLSKFLEITDAD----NVPKIWIDIHRRLLSRIKYRCSIDKWEGTLKKCLVNVLG-YESELA-NLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMYKENLEEE---SFKIVAESLEDLNNIL 613
            P FA +CSF++ +G  L++  L   +L + L+    D     VPK  +++H +L+ +I    + D+WE    K L+ +   + S  A  +    Y  +S E +  +L  L +CQFD N+KFK  +N +    +R QP G D  G +YW  +D D ++ MY E  +++   S+K +  +  +L   L
Sbjct:   21 PNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWE----KYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKYLCECQFDDNLKFKNIINEEDADTMRLQPIGRDKDGLMYWYQLDQDHNVRMYIEEQDDQDGSSWKCIVRNRNELAETL 202          
BLAST of PHD-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9NRL2|BAZ1A_HUMAN (Bromodomain adjacent to zinc finger domain protein 1A OS=Homo sapiens OX=9606 GN=BAZ1A PE=1 SV=2)

HSP 1 Score: 70.0922 bits (170), Expect = 1.061e-10
Identity = 25/48 (52.08%), Postives = 34/48 (70.83%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHK 1765
            C+IC K    E ++LCD CD GHH  C++P L  +PEG+WFCP+C+ K
Sbjct: 1151 CKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPK 1198          
BLAST of PHD-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8UVR5|BAZ1A_XENLA (Bromodomain adjacent to zinc finger domain protein 1A (Fragment) OS=Xenopus laevis OX=8355 GN=baz1a PE=2 SV=1)

HSP 1 Score: 69.3218 bits (168), Expect = 1.216e-10
Identity = 25/57 (43.86%), Postives = 38/57 (66.67%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEK 1792
            C++C K    E ++LCD CD GHH  C++P L  +PEG+WFCP+C  K+  ++L  +
Sbjct:  225 CKVCRKKGDGESMVLCDGCDRGHHIYCVRPKLKYVPEGDWFCPECHPKQRSHRLPSR 281          
BLAST of PHD-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9DE13|BAZ2B_CHICK (Bromodomain adjacent to zinc finger domain protein 2B OS=Gallus gallus OX=9031 GN=BAZ2B PE=2 SV=1)

HSP 1 Score: 68.9366 bits (167), Expect = 2.621e-10
Identity = 30/68 (44.12%), Postives = 41/68 (60.29%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKN 1825
            CQIC K +  E++LLCD CD G H  C +P +  IP+G+WFCP C     I K S +  +L+K  +K 
Sbjct: 1898 CQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPAC-----IAKASGQTLKLKKLQIKG 1960          
BLAST of PHD-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9UIF8|BAZ2B_HUMAN (Bromodomain adjacent to zinc finger domain protein 2B OS=Homo sapiens OX=9606 GN=BAZ2B PE=1 SV=3)

HSP 1 Score: 68.9366 bits (167), Expect = 3.138e-10
Identity = 30/68 (44.12%), Postives = 41/68 (60.29%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKN 1825
            CQIC K +  E++LLCD CD G H  C +P +  IP+G+WFCP C     I K S +  +++K  VK 
Sbjct: 1934 CQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPAC-----IAKASGQTLKIKKLHVKG 1996          
BLAST of PHD-type domain-containing protein vs. TrEMBL
Match: A0A4Z2DBI6 (Remodeling and spacing factor 1 isoform 2 OS=Schistosoma japonicum OX=6182 GN=EWB00_002585 PE=4 SV=1)

HSP 1 Score: 170.244 bits (430), Expect = 1.972e-39
Identity = 83/150 (55.33%), Postives = 100/150 (66.67%), Query Frame = 2
Query: 1469 IKETWDDKPESDFDPDKISISSDEETSKARGRNYFRQKSYKKE------KH-DIDDK--PCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNILS 1891
            I   W D PESDFDP  + I SD + S   GRN  RQK  +K+       H ++D+K  PCQIC K+++P+ ILLCD CD GHHAMCL P L +IPEG+WFCP+CQH  LI+ L+E IT LE    K     RMQERLNFVNISM+NIL 
Sbjct:  169 INSEWSDAPESDFDPSGLDIQSDAD-SVTDGRNLARQKRLQKKFESNSSTHCNVDEKEEPCQICFKSHLPDWILLCDRCDLGHHAMCLSPPLHVIPEGDWFCPRCQHTALISALNETITVLETESKKRNIWKRMQERLNFVNISMTNILG 317          
BLAST of PHD-type domain-containing protein vs. TrEMBL
Match: A0A4Z2DBS3 (Remodeling and spacing factor 1 isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_002585 PE=4 SV=1)

HSP 1 Score: 170.244 bits (430), Expect = 3.667e-39
Identity = 83/150 (55.33%), Postives = 100/150 (66.67%), Query Frame = 2
Query: 1469 IKETWDDKPESDFDPDKISISSDEETSKARGRNYFRQKSYKKE------KH-DIDDK--PCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNILS 1891
            I   W D PESDFDP  + I SD + S   GRN  RQK  +K+       H ++D+K  PCQIC K+++P+ ILLCD CD GHHAMCL P L +IPEG+WFCP+CQH  LI+ L+E IT LE    K     RMQERLNFVNISM+NIL 
Sbjct:  340 INSEWSDAPESDFDPSGLDIQSDAD-SVTDGRNLARQKRLQKKFESNSSTHCNVDEKEEPCQICFKSHLPDWILLCDRCDLGHHAMCLSPPLHVIPEGDWFCPRCQHTALISALNETITVLETESKKRNIWKRMQERLNFVNISMTNILG 488          
BLAST of PHD-type domain-containing protein vs. TrEMBL
Match: A0A4S2L8M0 (PHD-type domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_009189 PE=4 SV=1)

HSP 1 Score: 166.392 bits (420), Expect = 5.124e-38
Identity = 75/145 (51.72%), Postives = 99/145 (68.28%), Query Frame = 2
Query: 1481 WDDKPESDFDPDKISISSDEETSKARGRNYFRQKSYKKEKHDID--------DKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNILS 1891
            W+DKPESDFDPD I   SD + S  +GRN  RQK  +++   I         + PCQ+C + ++PE +LLCD CD GHHAMCL+P L+IIPEG+WFCP+CQH  L++ L+E    ++    K T   RMQERLN+VNISM+NIL+
Sbjct:  399 WNDKPESDFDPDDIGSDSDAD-SLTQGRNLARQKRLQRKLSSIGAGHLVPEQESPCQVCFRCHLPEWMLLCDRCDLGHHAMCLRPPLLIIPEGDWFCPRCQHATLVSALAECADAVDAEQKKQTLFKRMQERLNYVNISMTNILA 542          

HSP 2 Score: 78.9518 bits (193), Expect = 6.028e-11
Identity = 32/84 (38.10%), Postives = 55/84 (65.48%), Query Frame = 2
Query:  380 ILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMYKENLEEESFKIVAESLEDLNNILKELSEV 631
            +L +L + QFD+N  FKEKVNL+   DLR +P G+D+ G  YWL  D ++++++Y+E  E E  ++V E+ +++  +  EL + 
Sbjct:    1 MLLLLLETQFDRNQAFKEKVNLRSAVDLRFRPLGTDVWGRNYWLLKDSEVNVLLYREEAEHEKIRLVCETTDEIRQLHHELKDA 84          
BLAST of PHD-type domain-containing protein vs. TrEMBL
Match: A0A5J4NBQ1 (PHD-type domain-containing protein OS=Paragonimus westermani OX=34504 GN=DEA37_0012010 PE=4 SV=1)

HSP 1 Score: 166.392 bits (420), Expect = 6.188e-38
Identity = 83/171 (48.54%), Postives = 108/171 (63.16%), Query Frame = 2
Query: 1451 SEGSISIKETWDDKPESDFDPDKISISSDEETSKARGRNYFRQKSYKK-------------EKHDIDDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNILSKSQERKQIQKS 1924
            S+G +     W DKPESDF+PD +S +SD + S  +GRN  RQK  ++             E  D  D+PCQIC K+ +PE +LLCD CD GHHAMCL PSL +IPEG+WFCP+CQH  L+  L E    ++    K T   RMQERLN+VNISM+NIL+  +E + I K+
Sbjct:  444 SKGKVDHNMDWFDKPESDFNPDDLSANSDTD-SLTQGRNLARQKRLQRRLSNSATVPISVVEGEDEKDEPCQICQKSCMPEWLLLCDRCDLGHHAMCLCPSLFVIPEGDWFCPRCQHATLLTALLECADAVDAERKKQTIWKRMQERLNYVNISMTNILADDEEDEGIDKT 613          

HSP 2 Score: 93.2041 bits (230), Expect = 2.532e-15
Identity = 45/125 (36.00%), Postives = 76/125 (60.80%), Query Frame = 2
Query:  293 LVNVLGYESELANLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMYKENLEEESFKIVAESLEDLNNILKELSEVDCEKVNLSQLYS 667
            L N  G +SE A      Y+ +SA  R K+L  L + QFD+N  FK+KVNL+   DLR +P GSD+ G IYWL  D ++++++Y+E+ E+E+  ++ E+  ++  +   L +V   + NL+ + +
Sbjct:   11 LQNGTGVKSEHAT--SLAYYSLSAATRTKVLLSLLESQFDRNQGFKDKVNLRPSVDLRFRPLGSDVWGRIYWLLKDSEVNVLLYREDTEDETILLICETTNEIRELHDRLKDVCPSEPNLATILA 133          
BLAST of PHD-type domain-containing protein vs. TrEMBL
Match: A0A183QLK9 (PHD-type domain-containing protein OS=Schistosoma rodhaini OX=6188 PE=4 SV=1)

HSP 1 Score: 166.777 bits (421), Expect = 6.366e-38
Identity = 82/150 (54.67%), Postives = 99/150 (66.00%), Query Frame = 2
Query: 1469 IKETWDDKPESDFDPDKISISSDEETSKARGRNYFRQKSYKKEKH-------DIDDK--PCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNILS 1891
            I   W D PESDFDP+ + I SD + S   GRN  RQK  +K+         ++D+K  PCQ+C K+++P+ ILLCD CD GHHAMCL P L IIPEG+WFCP+CQH  LI+ L E IT LE    K     RMQERLNFVNISM+NIL 
Sbjct:  556 INPEWSDAPESDFDPNGLDIQSDAD-SVTDGRNLARQKRLQKKFESNPSTNCNVDEKEEPCQVCFKSHLPDWILLCDRCDLGHHAMCLSPPLHIIPEGDWFCPRCQHATLISALKETITVLEAESKKRNIWKRMQERLNFVNISMTNILG 704          

HSP 2 Score: 142.124 bits (357), Expect = 2.362e-30
Identity = 132/450 (29.33%), Postives = 205/450 (45.56%), Query Frame = 2
Query:   74 LKELPEFASLCSFIQLFGEELNVTLSHCQLSKFLEITDADNVPKIWIDIHRRLLSRIKYRCSIDKWEGTLKKCL------VNVLGYESELANLN---GTN----------------YFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMYKENLEEESFKIVAESLEDLNNILKELSEVDCEKVNLSQLYSVNSPSDDV---DHSRN------QSPIL-------DNISGILEKATNKLIPTKMETNDLSVDIKN--EGIDTEIDYSTNEPILDDIQPKSEEILKI----------ETETENDKITTEI------------------CTSESM--PNENLNKNAN-----SCVSP------EKSKKKLGRKQKEISPCNEDESNANIGLRRSERKRKPVNLFSITYSDSCKKMKRDVP 1171
            L+ LP+FA+LCSF+  FG +L + L+  QL  FL + ++    KIW  +H +LL+++KYR   D+WE  L + L      ++ +   +EL  LN   G N                Y+ +S   R K L  L + QFD+N  FK+K NL+   DLR  P G D+ G  YWL  D DI+I +Y+E+ +E +F+++ ES +D+  +++EL E   E   L  ++     SD     DH  N       SP L       D++          L P        + D K     +D  +  S    I   ++P+S+E + +          +T+ +N  +  EI                  CT+E +  P ++ N++ N     S V P      +KS+K    K  EI    +D       LRRS R+RKPV +F+I  + S K+ K   P
Sbjct:   21 LRSLPDFAALCSFLTFFGSDLGIHLTFPQLYDFLALQNSAKT-KIWETLHVKLLNKLKYRARPDRWEPVLGRFLLSHGLHIDGIQTAAELL-LNSECGNNEKLDVFIQKPSGYVSSYYRLSPNVRVKTLLCLLETQFDRNQPFKDKANLRSPVDLRFPPLGIDVWGRSYWLLKDSDINIYLYREDHQENNFQLLCESFDDVRGLIEELKEAFSEDEKLESIFKKKQASDRSNLKDHLENLIQDGVASPELEISKNDEDSVISPPSHPNVCLKPAITPPPTPTCDQKPTIHSVDMLLAISK---IEHSVKPESQENVGLSEEMVSSNRGKTDDQNRNVIHEIEVGQKCVDVNAEYHTKQECTTEQVLRPEDDCNEHTNQDSESSAVEPCTTVLSKKSRKNSSIKSSEIVVNEQD-------LRRSSRQRKPVQVFNIQPTQS-KRPKLSTP 457          
BLAST of PHD-type domain-containing protein vs. Ensembl Cavefish
Match: rsf1b.1 (remodeling and spacing factor 1b, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-030131-5829])

HSP 1 Score: 116.316 bits (290), Expect = 7.466e-26
Identity = 49/95 (51.58%), Postives = 66/95 (69.47%), Query Frame = 2
Query: 1613 DKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNILSKS 1897
            D PC+ C   N PE+ILLCD CD G+H  CL+P LMIIP+GEWFCP CQHK L +KL E++  ++ ++ K     R +ERL +V IS+ NI++ S
Sbjct:  764 DDPCKHCGLPNHPELILLCDSCDNGYHTACLRPPLMIIPDGEWFCPPCQHKLLCDKLEEQLVNIDAALKKKERAERRKERLVYVGISVENIITPS 858          

HSP 2 Score: 97.8265 bits (242), Expect = 3.740e-20
Identity = 58/182 (31.87%), Postives = 97/182 (53.30%), Query Frame = 2
Query:   86 PEFASLCSFIQLFGEELNVT-LSHCQLSKFLEITDADNVPKIWIDIHRRLLSRIKYRCSIDKWEGTLKKCLVNVLG-YESELA-NLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMY---KENLEEESFKIVAESLEDLNNIL 613
            P FA +CSF++ +G +L++  L+  QL +     D      + +D+H +LL +I    S D+WE    K LV +   + +  A  L    Y  ++ E +  IL  L +CQFD N+KFK  +N +    +R QP G D  G +YW  +D D ++ +Y   +++L+  S+K +  + +DL  IL
Sbjct:   16 PSFAVICSFLERYGAQLDLPELTFPQLER-----DVGGKLSLLVDLHVKLLRKIGKSVSADRWE----KYLVRICQEFNTTWAWELEKKGYLEMTVECKTGILKYLCECQFDDNVKFKTAINEEDPDKMRLQPIGRDKDGLMYWFQLDQDHNVRVYVEEQDDLDGSSWKCIVRNRDDLAQIL 188          
BLAST of PHD-type domain-containing protein vs. Ensembl Cavefish
Match: rsf1b.1 (remodeling and spacing factor 1b, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-030131-5829])

HSP 1 Score: 104.76 bits (260), Expect = 6.072e-23
Identity = 63/182 (34.62%), Postives = 103/182 (56.59%), Query Frame = 2
Query:   86 PEFASLCSFIQLFGEELNVT-LSHCQLSKFLEITDADNVPKIWIDIHRRLLSRIKYRCSIDKWEGTLKKCLVNVLG-YESELA-NLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMY---KENLEEESFKIVAESLEDLNNIL 613
            P FA +CSF++ +G +L++  L+  QL ++LE T A   PK+ +D+H +LL +I    S D+WE    K LV +   + +  A  L    Y  ++ E +  IL  L +CQFD N+KFK  +N +    +R QP G D  G +YW  +D D ++ +Y   +++L+  S+K +  + +DL  IL
Sbjct:   16 PSFAVICSFLERYGAQLDLPELTFPQLERYLEETTA---PKLLVDLHVKLLRKIGKSVSADRWE----KYLVRICQEFNTTWAWELEKKGYLEMTVECKTGILKYLCECQFDDNVKFKTAINEEDPDKMRLQPIGRDKDGLMYWFQLDQDHNVRVYVEEQDDLDGSSWKCIV-NRDDLAQIL 189          
BLAST of PHD-type domain-containing protein vs. Ensembl Cavefish
Match: RSF1 (remodeling and spacing factor 1 [Source:NCBI gene;Acc:103037331])

HSP 1 Score: 102.834 bits (255), Expect = 1.313e-21
Identity = 63/185 (34.05%), Postives = 102/185 (55.14%), Query Frame = 2
Query:   86 PEFASLCSFIQLFGEELNVT-LSHCQLSKFLEITDADNVPKIWIDIHRRLLSRIKYRCSIDKWEGTLKKCLVNVLG-YESELA-NLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMY---KENLEEESFKIVAESLEDLNNILKEL 622
            P FA +CSF++ +G  L++  LS  ++ +FL   D   VP+  +++H +LL ++    S ++WE    K LV V   + S  A  L    Y  +  E +A IL  L +CQFD N+KFK  VN +    +R QP G D  G +YW  +D D ++ +Y   +++L+  S+K +  +  DL +IL+ L
Sbjct:   16 PSFAVVCSFLERYGAALDLPELSFPEMERFLR--DRSAVPQPLVELHVKLLRKLGKTVSSERWE----KYLVKVCQEFNSTWAWELESKGYPEMPMECKADILKYLCECQFDDNVKFKTAVNEEDPDQMRLQPIGRDKEGLLYWFQLDQDQNVRVYVEEQDDLDGSSWKCIVRNRNDLADILEAL 194          

HSP 2 Score: 101.679 bits (252), Expect = 2.843e-21
Identity = 47/89 (52.81%), Postives = 61/89 (68.54%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNIL 1888
            C+ C   N PE+ILLCD CD G+H  CL+P LMIIP+GEWFCP CQHK L  KL E++  L+ ++ K     R +ERL +V IS+ NI+
Sbjct:  851 CKHCSLPNHPELILLCDLCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCEKLEEQLLNLDTALKKRERAERRRERLVYVGISVENII 939          
BLAST of PHD-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000010217.2 (pep primary_assembly:Astyanax_mexicanus-2.0:19:378618:383521:-1 gene:ENSAMXG00000009943.2 transcript:ENSAMXT00000010217.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 67.3958 bits (163), Expect = 3.812e-11
Identity = 25/45 (55.56%), Postives = 31/45 (68.89%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKC 1756
            CQ+C K +  E++LLCD CD G H  C KP +  IPEG+WFCP C
Sbjct:  195 CQMCRKGDNEELLLLCDGCDKGCHTYCHKPQISTIPEGDWFCPAC 239          
BLAST of PHD-type domain-containing protein vs. Ensembl Cavefish
Match: phrf1 (PHD and ring finger domains 1 [Source:ZFIN;Acc:ZDB-GENE-030131-624])

HSP 1 Score: 66.2402 bits (160), Expect = 2.266e-10
Identity = 31/87 (35.63%), Postives = 51/87 (58.62%), Query Frame = 2
Query: 1580 KSYKKEKHDID--DKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAK 1834
            K+ ++E+ D+D     C++C  ++  + +LLCD CD G+H  CL P L  +P  EWFCP C      N  SE+ +E E +++  T++
Sbjct:  172 KATEEEQVDVDLEQTSCEVCGGSDREDRLLLCDGCDAGYHMECLTPPLDAVPVEEWFCPGC----APNSRSERSSEDESNVLPTTSR 254          
BLAST of PHD-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008781.1 (pep scaffold:Pmarinus_7.0:GL478673:190102:212513:-1 gene:ENSPMAG00000007949.1 transcript:ENSPMAT00000008781.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.077 bits (144), Expect = 2.160e-9
Identity = 30/103 (29.13%), Postives = 51/103 (49.51%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQ--HKKLINKLSEKITELEKSMVKNTAKMRM-QERLNFVNISMSNILSKSQERKQIQK 1921
            C++C  ++  + +LLCD CD G+H  CL P+L  +P  EWFCP+C+  H++      E    L     +     R  Q  +    +++S I    Q R+ + +
Sbjct:  178 CEVCRSSDREDRLLLCDGCDAGYHMECLDPALDTVPVEEWFCPQCRPVHQQTARAGEEGAGPLGVGHRQRRVIARTRQSEIVRTRVNISRITRTQQIRRAVSQ 280          
BLAST of PHD-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008148.1 (pep scaffold:Pmarinus_7.0:GL498397:3423:4217:1 gene:ENSPMAG00000007368.1 transcript:ENSPMAT00000008148.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 52.373 bits (124), Expect = 1.251e-8
Identity = 35/101 (34.65%), Postives = 54/101 (53.47%), Query Frame = 2
Query:  281 LKKCLVNVLGYESELANLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMYKENLEEE-SFKIV 580
            L+ C  + L +  EL  L    Y  ++   +  IL  L + QFD N+KFK  VN +    +R QP G D  G  YWL +D D ++ +Y E  ++E S+++V
Sbjct:    2 LQICQDHNLTWAWELETLG---YPKLNPSYKLVILKHLCESQFDDNVKFKNVVNEEDEDAMRLQPIGRDRDGLAYWLQLDDDFNVRLYTEEQDDEASWRLV 99          
BLAST of PHD-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004580.1 (pep scaffold:Pmarinus_7.0:GL479395:1031:10600:-1 gene:ENSPMAG00000004170.1 transcript:ENSPMAT00000004580.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.6102 bits (135), Expect = 1.630e-8
Identity = 33/106 (31.13%), Postives = 50/106 (47.17%), Query Frame = 2
Query: 1610 DDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKC--------QHKKLINKL--------SEKITELEKSMVKNTAKMRMQERLNFVNISMS 1879
            ++ PC+ C  ++  E +LLCD CD G H  CL P L  IP  EWFCP C        +   L+  L        +  I  +    ++  A+ R++ R+N   +S S
Sbjct:   96 EETPCRACGLSDREERMLLCDACDAGFHMECLVPPLDSIPVEEWFCPTCLPRAPSIGRAPALLTLLCLWSATVITNIIVSVAPGPMRVIARERVRARVNRSRLSFS 201          
BLAST of PHD-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006111.1 (pep scaffold:Pmarinus_7.0:GL477389:137964:150286:1 gene:ENSPMAG00000005519.1 transcript:ENSPMAT00000006111.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.4546 bits (132), Expect = 2.434e-8
Identity = 23/56 (41.07%), Postives = 33/56 (58.93%), Query Frame = 2
Query: 1604 DIDDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKL 1771
            DI +  C +C ++     +L+CD C   +H  CL+P L  IP+G W CPKCQ + L
Sbjct:  132 DIHEDFCSVCKRSG---QLLMCDTCSRVYHLECLEPPLKAIPKGMWICPKCQEQVL 184          
BLAST of PHD-type domain-containing protein vs. Ensembl Sea Lamprey
Match: kdm5c (lysine (K)-specific demethylase 5C [Source:ZFIN;Acc:ZDB-GENE-060810-94])

HSP 1 Score: 55.4546 bits (132), Expect = 6.443e-8
Identity = 23/61 (37.70%), Postives = 35/61 (57.38%), Query Frame = 2
Query: 1574 RQKSYKKEKHDIDDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKC 1756
            RQ++       I+   C +C + +  + +LLCD CD  +H  CL P L  +P+G+W CPKC
Sbjct:  300 RQRTGALSAQFIEMYVCLVCGRGDEEDKLLLCDGCDDSYHTFCLIPPLQDVPKGDWRCPKC 360          
BLAST of PHD-type domain-containing protein vs. Ensembl Yeast
Match: JHD2 (JmjC domain family histone demethylase; promotes global demethylation of H3K4 and repression of noncoding intergenic transcription during sporulation; removes methyl groups added by Set1p methyltransferase; negatively regulated by H3K14 acetylation; protein levels regulated by Not4p polyubiquitin-mediated degradation; regulates sporulation timing by extending period of active transcription in opposition to programmed global transcriptional quiescence; regulates rDNA silencing [Source:SGD;Acc:S000003880])

HSP 1 Score: 54.299 bits (129), Expect = 9.448e-8
Identity = 22/49 (44.90%), Postives = 27/49 (55.10%), Query Frame = 2
Query: 1610 DDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKC 1756
            DD  C +C K N P+  +LCD CD   H  CL P L  +P G+W C  C
Sbjct:  234 DDDACIVCRKTNDPKRTILCDSCDKPFHIYCLSPPLERVPSGDWICNTC 282          
BLAST of PHD-type domain-containing protein vs. Ensembl Yeast
Match: RCO1 (Essential component of the Rpd3S histone deacetylase complex; interacts with Eaf3p [Source:SGD;Acc:S000004680])

HSP 1 Score: 50.8322 bits (120), Expect = 1.120e-6
Identity = 44/150 (29.33%), Postives = 65/150 (43.33%), Query Frame = 2
Query: 1469 IKETWDDKPESDFDPDKIS------ISSDEET----SKARGRNYFRQKSYKKEK-------HDIDDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSL--MIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNF 1861
            I  T D +PESD D  K+S      I S   T    SK  G+N  +  S   EK         ID +    C   N     L CD C    H +CL P +    +P+G+W C +C+ K  IN     + ++E + +K    +++  +L F
Sbjct:  192 INRTRDREPESDRDNKKLSNIRTKIILSTNATYDSKSKLFGQNSIKSTSNASEKIFRDKNNSTIDFENEDFCSACNQSGSFLCCDTCPKSFHFLCLDPPIDPNNLPKGDWHCNECKFKIFINNSMATLKKIESNFIKQNNNVKIFAKLLF 341          
BLAST of PHD-type domain-containing protein vs. Ensembl Nematostella
Match: EDO44054 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWY0])

HSP 1 Score: 68.5514 bits (166), Expect = 9.736e-13
Identity = 26/48 (54.17%), Postives = 32/48 (66.67%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHK 1765
            C++C +    E +LLCD CD GHH  CLKP +  IPEG WFCP C+ K
Sbjct:    1 CKLCRRKGDAEKMLLCDACDRGHHMYCLKPPIKHIPEGNWFCPDCRPK 48          
BLAST of PHD-type domain-containing protein vs. Ensembl Nematostella
Match: EDO44814 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUU7])

HSP 1 Score: 61.6178 bits (148), Expect = 4.905e-10
Identity = 23/45 (51.11%), Postives = 30/45 (66.67%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKC 1756
            CQ+C K +  E++LLCD CD G+H  C  P L  IPEG+W+C  C
Sbjct:  102 CQMCRKGDNEELLLLCDGCDRGYHTYCCMPKLTTIPEGDWYCMDC 146          
BLAST of PHD-type domain-containing protein vs. Ensembl Nematostella
Match: EDO35777 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKI4])

HSP 1 Score: 57.7658 bits (138), Expect = 2.677e-9
Identity = 25/49 (51.02%), Postives = 34/49 (69.39%), Query Frame = 2
Query: 1622 CQICL-KNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHK 1765
            C++C  K+   E +LLCD+C+ G+H  CL+PSL  IP GEW CP C+ K
Sbjct:    1 CKVCRRKSRSDETLLLCDECNMGYHLFCLRPSLDRIPLGEWKCPACKVK 49          
BLAST of PHD-type domain-containing protein vs. Ensembl Nematostella
Match: EDO31764 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX13])

HSP 1 Score: 52.7582 bits (125), Expect = 9.144e-9
Identity = 21/49 (42.86%), Postives = 27/49 (55.10%), Query Frame = 2
Query: 1610 DDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKC 1756
            D K C +C    +   +LLCD+CD G+H  CL P L   P+G W C  C
Sbjct:   30 DCKTCHLCDTGEVQNELLLCDNCDRGYHMSCLDPKLTKAPKGAWHCVLC 78          
BLAST of PHD-type domain-containing protein vs. Ensembl Nematostella
Match: EDO39585 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9J4])

HSP 1 Score: 53.5286 bits (127), Expect = 4.500e-7
Identity = 23/60 (38.33%), Postives = 32/60 (53.33%), Query Frame = 2
Query: 1604 DIDDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKL 1783
            DI    C++C        +L CD C   +H  CL P +M +P GEW CP+CQ + L  K+
Sbjct:    8 DIHSDYCRVCKDGG---QLLCCDKCPMAYHLKCLIPPMMRVPTGEWKCPRCQSEPLKGKV 64          
BLAST of PHD-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000032858.1 (remodeling and spacing factor 1 [Source:NCBI gene;Acc:101166729])

HSP 1 Score: 103.605 bits (257), Expect = 6.783e-22
Identity = 45/89 (50.56%), Postives = 60/89 (67.42%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNIL 1888
            C  C   N PE+ILLCD CD G+H  CL+P +M+IP+GEWFCP CQHK L  KL E++  L+ ++ K     R +ERL +V IS+ NI+
Sbjct:  515 CSHCGLPNHPELILLCDSCDSGYHTACLRPPVMLIPDGEWFCPPCQHKLLCEKLEEQLQNLDSALKKRERAERRRERLVYVGISVENII 603          
BLAST of PHD-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000002636.2 (remodeling and spacing factor 1 [Source:NCBI gene;Acc:101166729])

HSP 1 Score: 101.679 bits (252), Expect = 2.971e-21
Identity = 45/89 (50.56%), Postives = 60/89 (67.42%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNIL 1888
            C  C   N PE+ILLCD CD G+H  CL+P +M+IP+GEWFCP CQHK L  KL E++  L+ ++ K     R +ERL +V IS+ NI+
Sbjct:  828 CSHCGLPNHPELILLCDSCDSGYHTACLRPPVMLIPDGEWFCPPCQHKLLCEKLEEQLQNLDSALKKRERAERRRERLVYVGISVENII 916          

HSP 2 Score: 98.5969 bits (244), Expect = 2.299e-20
Identity = 59/186 (31.72%), Postives = 100/186 (53.76%), Query Frame = 2
Query:   86 PEFASLCSFIQLFGEELNVT-LSHCQLSKFLEITDADNVPKIWIDIHRRLLSRIKYRCSIDKWEGTLKKC---LVNVLGYESELANLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMYKE---NLEEESFKIVAESLEDLNNILKEL 622
            P FA +CSF++ +G  L++  ++  QL ++L  T A  V K  +D+H +LL ++    + D+WE  L K    L +   +E     L    Y  +S E ++ IL  L +CQFD N+KFK  +N +    +R QP G D  G +YW+ +D + +I +Y E   +L+  +++ +  +  DL   L+ L
Sbjct:   16 PSFAEVCSFLERYGPALDLPEMTFPQLERYLRDTTA--VSKPLVDLHVKLLRKLGKSVTTDRWEKYLAKVCQELNSTWAWE-----LEQKGYQEMSMECKSSILKYLCECQFDDNLKFKMMINDEDPEKMRLQPVGRDRQGLLYWMQLDQEQNIRLYTEEQDDLDGSTWRCIVRTRNDLAEALELL 194          
BLAST of PHD-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000029236.1 (remodeling and spacing factor 1 [Source:NCBI gene;Acc:101155159])

HSP 1 Score: 97.0561 bits (240), Expect = 5.791e-20
Identity = 38/67 (56.72%), Postives = 50/67 (74.63%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVK 1822
            C+ C   N PE+ILLCD CD G+H  CL+P LMIIP+GEWFCP CQHK+L +KL E++  L+ ++ K
Sbjct:  835 CKHCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKQLCDKLEEQLLNLDAALKK 901          

HSP 2 Score: 96.2857 bits (238), Expect = 1.125e-19
Identity = 59/189 (31.22%), Postives = 101/189 (53.44%), Query Frame = 2
Query:   86 PEFASLCSFIQLFGEELNVT-LSHCQLSKFLEITDADNVPKIWIDIHRRLLSRIKYRCSIDKWEGTLKK-CLVNVLGYESELANLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMY---KENLEEESFKIVAESLEDLNNILKELSEVDC 637
            P +A +CSF++ +G  L++  L+  QL ++L+  D   VPK+ +D+H +LL +I    + D+WE  L K C    + +  EL       Y  +  E++  IL  L + QFD+N+KFK  +N +    +R QP G D  G +YW   D D ++ +Y   +++L+  S+K +   +    + L  L+ V C
Sbjct:   16 PNYAVICSFLERYGALLDLPELTFPQLERYLQ--DTSTVPKLLVDLHVKLLRKIGKSVTADRWEKYLVKVCQEFNMTWAWELEE---KGYKQMPMESKTGILKFLCESQFDENVKFKTAINDEDPDKMRLQPIGRDKDGQMYWYQQDQDNNVRLYIEEQDDLDGASWKCIVRRVGKRMSKLVPLNLVSC 199          
BLAST of PHD-type domain-containing protein vs. Ensembl Medaka
Match: BAZ1A (bromodomain adjacent to zinc finger domain 1A [Source:NCBI gene;Acc:101167005])

HSP 1 Score: 69.3218 bits (168), Expect = 2.473e-11
Identity = 25/49 (51.02%), Postives = 34/49 (69.39%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKK 1768
            C+IC +    + +LLCD CD GHH  CL+P L  +PEG+WFCP C+ K+
Sbjct: 1117 CRICRRKGDADNMLLCDGCDRGHHTHCLRPRLKSVPEGDWFCPDCRPKQ 1165          
BLAST of PHD-type domain-containing protein vs. Ensembl Medaka
Match: baz2a (bromodomain adjacent to zinc finger domain 2A [Source:NCBI gene;Acc:101161807])

HSP 1 Score: 65.0846 bits (157), Expect = 5.006e-10
Identity = 26/48 (54.17%), Postives = 32/48 (66.67%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHK 1765
            CQ+C K +  E +LLCD CD G H  CLKP +  +PEG+WFCP C  K
Sbjct: 2436 CQVCRKGDNDECLLLCDSCDRGCHMYCLKPKITQVPEGDWFCPTCTAK 2483          
BLAST of PHD-type domain-containing protein vs. Planmine SMEST
Match: SMESG000047306.1 (SMESG000047306.1)

HSP 1 Score: 1590.86 bits (4118), Expect = 0.000e+0
Identity = 1027/1032 (99.52%), Postives = 1030/1032 (99.81%), Query Frame = 2
Query:   65 MSSLKELPEFASLCSFIQLFGEELNVTLSHCQLSKFLEITDADNVPKIWIDIHRRLLSRIKYRCSIDKWEGTLKKCLVNVLGYESELANLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMYKENLEEESFKIVAESLEDLNNILKELSEVDCEKVNLSQLYSVNSPSDDVDHSRNQSPILDNISGILEKATNKLIPTKMETNDLSVDIKNEGIDTEIDYSTNEPILDDIQPKSEEILKIETETENDKITTEICTSESMPNENLNKNANSCVSPEKSKKKLGRKQKEISPCNEDESNANIGLRRSERKRKPVNLFSITYSDSCKKMKRDVPKTENHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFSLETXXXXXXXXXXXXXXXXXXXXXXXXXXXPWENAXXXXXXXXXXXXXXXVYLNEESEGSISIKETWDDKPESDFDPDKISISSDEETSKARGRNYFRQKSYKKEKHDIDDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNILSKSQERKQIQKSCCESEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKATRTRYKFRETSRKENTKYNFEEIDKMFDDALEHDEKYKLLKKXXXXXXXXXXXXXXXXXXXXXYDYSGIEPRKKSSGKDMANIVNEDEEQMPARPMVKKKRLXXXXXXXXXXXXXXXXFKLSDQSDSELDEYECPEANGSNCSXXXXXXXWVVSXXXXXXXXXXXXXXXXSVLESSGGYSRPRRNATRNINYRNMLGXXXXXXXXXPGDKSPEYESDDSNRKPPPVVSRKKDKHSGLIKKRIISDSEYEENSKSESIADSGSTEKLEVVKRKFKPDLNSDSEDEQQVTKVPLIDNEDNDASNDYNNDLXXXXXXXXXXXXXXXXXLAILNPMRAKAXXXXXXXXXXXXXXXXXLTISMSSNQDLNNQNTAPKV 3160
            MSSLKELPEFASLCSFIQLFGEELNVTLSHCQLSKFLEITDADNVPKIWIDIHRRLLSRIKYRCSIDKWEGTLKKCLVNVLGYESELANLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMYKENLEEESFKIVAESLEDLNNILKELSEVDCEKVNLSQLYSVNSPSDDVDHSRNQSPILDNISGILEKATNKLIPTKMETNDLSVDIK EGIDTEIDYSTNEPILDDIQPKSEEILKIETETENDKITTEICTSESMPNENLNKNANSCVSPEKSKKKLGRKQKEISPCNEDESNANIGLRRSERKRKPVNLFSITYSDSCKKMKRDVPKTENHSSKKIKETEKKLHKKSKEKRKKGRPKKSTEFSLETGKEKKKLKKNKKKHEKGKKHKKHKSKNPWENAESSD+HNNDAEEEDEVYLNEESEGSISIKETWDDKPESDFDPDKISISSDEETSKARGRNYFRQKSYKKEKHDIDDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNILSKSQERKQIQKSCCESESGSLTDCNSSSGSLSSSSGSYNSSDNSSKSGSKATRTRYKFRETSRKENTKYNFEEIDKMFDDALEHDEKYKLLKKEQESRDRRNSESSRGEESEPEYDYSGIEPRKKSSGKDMANIVNEDEEQMPARP+VKKKRLKYISDEDYEDDIKDTDFKLSDQSDSELDEYECPEANGSNCS DDDDDDWVVSRKRVTRKATKKKYKHRSVLESSGGYSRPRRNATRNINYRNMLGDEDEDEDEEPGDKSPEYESDDSNRKPPPVVSRKKDKHSGLIKKRIISDSEYEENSKSESIADSGSTEKLEVVKRKFKPDLNSDSEDEQQVTKVP+IDNEDNDASNDYNNDLIIDIKSSPISNIPIYPSLAILNPMRAKADEDDDVENEVESETECDLTISMSSNQDLNNQNTAPKV
Sbjct:    1 MSSLKELPEFASLCSFIQLFGEELNVTLSHCQLSKFLEITDADNVPKIWIDIHRRLLSRIKYRCSIDKWEGTLKKCLVNVLGYESELANLNGTNYFGISAENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLFVDIDISIIMYKENLEEESFKIVAESLEDLNNILKELSEVDCEKVNLSQLYSVNSPSDDVDHSRNQSPILDNISGILEKATNKLIPTKMETNDLSVDIKTEGIDTEIDYSTNEPILDDIQPKSEEILKIETETENDKITTEICTSESMPNENLNKNANSCVSPEKSKKKLGRKQKEISPCNEDESNANIGLRRSERKRKPVNLFSITYSDSCKKMKRDVPKTENHSSKKIKETEKKLHKKSKEKRKKGRPKKSTEFSLETGKEKKKLKKNKKKHEKGKKHKKHKSKNPWENAESSDDHNNDAEEEDEVYLNEESEGSISIKETWDDKPESDFDPDKISISSDEETSKARGRNYFRQKSYKKEKHDIDDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFVNISMSNILSKSQERKQIQKSCCESESGSLTDCNSSSGSLSSSSGSYNSSDNSSKSGSKATRTRYKFRETSRKENTKYNFEEIDKMFDDALEHDEKYKLLKKEQESRDRRNSESSRGEESEPEYDYSGIEPRKKSSGKDMANIVNEDEEQMPARPLVKKKRLKYISDEDYEDDIKDTDFKLSDQSDSELDEYECPEANGSNCS-DDDDDDWVVSRKRVTRKATKKKYKHRSVLESSGGYSRPRRNATRNINYRNMLGDEDEDEDEEPGDKSPEYESDDSNRKPPPVVSRKKDKHSGLIKKRIISDSEYEENSKSESIADSGSTEKLEVVKRKFKPDLNSDSEDEQQVTKVPIIDNEDNDASNDYNNDLIIDIKSSPISNIPIYPSLAILNPMRAKADEDDDVENEVESETECDLTISMSSNQDLNNQNTAPKV 1031          
BLAST of PHD-type domain-containing protein vs. Planmine SMEST
Match: SMESG000002851.1 (SMESG000002851.1)

HSP 1 Score: 65.855 bits (159), Expect = 2.046e-10
Identity = 26/50 (52.00%), Postives = 34/50 (68.00%), Query Frame = 2
Query: 1610 DDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQ 1759
            DDK C++C K +    +LLCD C+   H  CL+P+L  IPEGEWFCP C+
Sbjct: 1027 DDK-CRVCRKASDENSMLLCDSCNHAFHTFCLRPALHDIPEGEWFCPHCK 1075          
BLAST of PHD-type domain-containing protein vs. Planmine SMEST
Match: SMESG000068165.1 (SMESG000068165.1)

HSP 1 Score: 63.5438 bits (153), Expect = 9.664e-10
Identity = 27/54 (50.00%), Postives = 32/54 (59.26%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKL 1783
            CQIC K+     +LLCD CD G+H  C +P L  IPEG+WFC  C  K    KL
Sbjct: 1530 CQICRKDCNEAQLLLCDSCDQGYHTYCFRPPLSGIPEGQWFCHDCVSKATDQKL 1583          
BLAST of PHD-type domain-containing protein vs. Planmine SMEST
Match: SMESG000068165.1 (SMESG000068165.1)

HSP 1 Score: 63.5438 bits (153), Expect = 9.665e-10
Identity = 27/54 (50.00%), Postives = 32/54 (59.26%), Query Frame = 2
Query: 1622 CQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLINKL 1783
            CQIC K+     +LLCD CD G+H  C +P L  IPEG+WFC  C  K    KL
Sbjct: 1531 CQICRKDCNEAQLLLCDSCDQGYHTYCFRPPLSGIPEGQWFCHDCVSKATDQKL 1584          
BLAST of PHD-type domain-containing protein vs. Planmine SMEST
Match: SMESG000045165.1 (SMESG000045165.1)

HSP 1 Score: 58.9214 bits (141), Expect = 1.966e-8
Identity = 25/58 (43.10%), Postives = 35/58 (60.34%), Query Frame = 2
Query: 1604 DIDDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPSLMIIPEGEWFCPKCQHKKLIN 1777
            +I +  C+IC   N    +LLCD+C+ G+H  CL   L  IPEG+WFC +C +   IN
Sbjct:  165 EILNTTCEICNLGNNDHQLLLCDNCNRGYHIYCLADPLSEIPEGDWFCEECSNDMEIN 222          
The following BLAST results are available for this feature:
BLAST of PHD-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RSF11.464e-2652.75remodeling and spacing factor 1 [Source:HGNC Symbo... [more]
RSF11.873e-2653.76remodeling and spacing factor 1 [Source:HGNC Symbo... [more]
RSF12.521e-2653.76remodeling and spacing factor 1 [Source:HGNC Symbo... [more]
RSF14.894e-2653.76remodeling and spacing factor 1 [Source:HGNC Symbo... [more]
RSF11.974e-1732.30remodeling and spacing factor 1 [Source:HGNC Symbo... [more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
chd-33.380e-751.11Chromodomain-helicase-DNA-binding protein 3 homolo... [more]
baz-25.257e-744.90Bromodomain Adjacent to Zinc finger domain, 2A/2B,... [more]
dpff-18.811e-643.75Zinc finger protein dpff-1 [Source:UniProtKB/Swis... [more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG86775.404e-1831.69gene:FBgn0026577 transcript:FBtr0331677[more]
CG86775.404e-1831.69gene:FBgn0026577 transcript:FBtr0346586[more]
lid6.121e-1051.11gene:FBgn0031759 transcript:FBtr0079231[more]
lid6.121e-1051.11gene:FBgn0031759 transcript:FBtr0079232[more]
lid6.121e-1051.11gene:FBgn0031759 transcript:FBtr0307070[more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rsf1b.19.119e-2751.04remodeling and spacing factor 1b, tandem duplicate... [more]
rsf1b.16.737e-2651.04remodeling and spacing factor 1b, tandem duplicate... [more]
rsf1b.11.684e-2130.38remodeling and spacing factor 1b, tandem duplicate... [more]
baz2a3.665e-1151.02bromodomain adjacent to zinc finger domain, 2A [So... [more]
baz2ba1.811e-1052.08bromodomain adjacent to zinc finger domain, 2Ba [S... [more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
soat21.583e-2552.69sterol O-acyltransferase 2 [Source:Xenbase;Acc:XB-... [more]
soat21.871e-2552.69sterol O-acyltransferase 2 [Source:Xenbase;Acc:XB-... [more]
BAZ1A3.168e-1143.86bromodomain adjacent to zinc finger domain 1A [Sou... [more]
BAZ1A3.350e-1143.86bromodomain adjacent to zinc finger domain 1A [Sou... [more]
BAZ1A3.445e-1143.86bromodomain adjacent to zinc finger domain 1A [Sou... [more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rsf13.476e-2653.76remodeling and spacing factor 1 [Source:MGI Symbol... [more]
Baz1a4.672e-1150.00bromodomain adjacent to zinc finger domain 1A [Sou... [more]
Baz1a4.790e-1150.00bromodomain adjacent to zinc finger domain 1A [Sou... [more]
Baz2b5.476e-1144.12bromodomain adjacent to zinc finger domain, 2B [So... [more]
Baz2b5.476e-1144.12bromodomain adjacent to zinc finger domain, 2B [So... [more]
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BLAST of PHD-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q96T23|RSF1_HUMAN2.350e-2553.76Remodeling and spacing factor 1 OS=Homo sapiens OX... [more]
sp|Q9NRL2|BAZ1A_HUMAN1.061e-1052.08Bromodomain adjacent to zinc finger domain protein... [more]
sp|Q8UVR5|BAZ1A_XENLA1.216e-1043.86Bromodomain adjacent to zinc finger domain protein... [more]
sp|Q9DE13|BAZ2B_CHICK2.621e-1044.12Bromodomain adjacent to zinc finger domain protein... [more]
sp|Q9UIF8|BAZ2B_HUMAN3.138e-1044.12Bromodomain adjacent to zinc finger domain protein... [more]
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BLAST of PHD-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4Z2DBI61.972e-3955.33Remodeling and spacing factor 1 isoform 2 OS=Schis... [more]
A0A4Z2DBS33.667e-3955.33Remodeling and spacing factor 1 isoform 1 OS=Schis... [more]
A0A4S2L8M05.124e-3851.72PHD-type domain-containing protein OS=Opisthorchis... [more]
A0A5J4NBQ16.188e-3848.54PHD-type domain-containing protein OS=Paragonimus ... [more]
A0A183QLK96.366e-3854.67PHD-type domain-containing protein OS=Schistosoma ... [more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rsf1b.17.466e-2651.58remodeling and spacing factor 1b, tandem duplicate... [more]
rsf1b.16.072e-2334.62remodeling and spacing factor 1b, tandem duplicate... [more]
RSF11.313e-2134.05remodeling and spacing factor 1 [Source:NCBI gene;... [more]
ENSAMXT00000010217.23.812e-1155.56pep primary_assembly:Astyanax_mexicanus-2.0:19:378... [more]
phrf12.266e-1035.63PHD and ring finger domains 1 [Source:ZFIN;Acc:ZDB... [more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000008781.12.160e-929.13pep scaffold:Pmarinus_7.0:GL478673:190102:212513:-... [more]
ENSPMAT00000008148.11.251e-834.65pep scaffold:Pmarinus_7.0:GL498397:3423:4217:1 gen... [more]
ENSPMAT00000004580.11.630e-831.13pep scaffold:Pmarinus_7.0:GL479395:1031:10600:-1 g... [more]
ENSPMAT00000006111.12.434e-841.07pep scaffold:Pmarinus_7.0:GL477389:137964:150286:1... [more]
kdm5c6.443e-837.70lysine (K)-specific demethylase 5C [Source:ZFIN;Ac... [more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
JHD29.448e-844.90JmjC domain family histone demethylase; promotes g... [more]
RCO11.120e-629.33Essential component of the Rpd3S histone deacetyla... [more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO440549.736e-1354.17Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO448144.905e-1051.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO357772.677e-951.02Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO317649.144e-942.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO395854.500e-738.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000032858.16.783e-2250.56remodeling and spacing factor 1 [Source:NCBI gene;... [more]
ENSORLT00000002636.22.971e-2150.56remodeling and spacing factor 1 [Source:NCBI gene;... [more]
ENSORLT00000029236.15.791e-2056.72remodeling and spacing factor 1 [Source:NCBI gene;... [more]
BAZ1A2.473e-1151.02bromodomain adjacent to zinc finger domain 1A [Sou... [more]
baz2a5.006e-1054.17bromodomain adjacent to zinc finger domain 2A [Sou... [more]
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BLAST of PHD-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000047306.10.000e+099.52SMESG000047306.1[more]
SMESG000002851.12.046e-1052.00SMESG000002851.1[more]
SMESG000068165.19.664e-1050.00SMESG000068165.1[more]
SMESG000068165.19.665e-1050.00SMESG000068165.1[more]
SMESG000045165.11.966e-843.10SMESG000045165.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011300 ID=SMED30011300|Name=PHD-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=3333bp
CTATTTTGATCTTAATTGTTTATTTTTAATTTTTAACTTTCAATTTTTAT
AATTTATATTTCTTATGTCTTCTCTTAAAGAGCTACCTGAATTTGCATCT
TTATGTTCATTTATACAATTATTTGGAGAAGAGTTAAATGTTACATTATC
TCATTGTCAATTGTCTAAATTTCTTGAAATTACTGACGCAGATAATGTTC
CAAAAATTTGGATCGACATTCACAGAAGATTACTCAGTCGAATTAAATAT
CGTTGTTCCATAGATAAATGGGAAGGAACTCTGAAAAAATGTCTCGTAAA
TGTTTTAGGTTATGAATCCGAATTAGCAAATCTGAATGGCACTAATTATT
TTGGTATATCTGCAGAAAATCGAGCAAAAATTTTAAATATACTTTTTGAT
TGTCAATTTGACAAAAATATTAAATTTAAAGAAAAAGTAAATTTGAAGTT
AATTAGTGACCTTCGTACTCAACCATTTGGTAGTGATATTCACGGATGTA
TTTATTGGTTGTTTGTTGATATAGATATTAGTATTATTATGTATAAAGAG
AATTTAGAAGAAGAATCATTTAAGATTGTCGCAGAATCCCTTGAAGATTT
GAATAACATTCTAAAGGAACTTTCAGAAGTCGACTGTGAAAAAGTGAATT
TGTCTCAACTCTACTCAGTAAACAGTCCATCTGATGACGTAGATCATTCT
CGTAATCAGTCACCCATTCTTGATAATATATCTGGAATATTAGAAAAGGC
AACCAATAAATTAATTCCCACTAAAATGGAAACCAATGACCTCTCAGTGG
ATATTAAAAACGAAGGTATCGATACCGAAATTGATTATTCAACAAATGAA
CCGATTCTCGATGACATTCAACCGAAATCGGAAGAAATATTGAAAATTGA
AACTGAAACTGAAAACGATAAAATCACAACTGAAATATGCACATCAGAAT
CTATGCCAAACGAAAATTTGAACAAAAACGCGAATAGTTGTGTTTCACCG
GAAAAATCCAAGAAAAAGCTAGGAAGAAAGCAAAAAGAAATCTCACCGTG
TAATGAAGATGAATCGAATGCAAATATTGGTTTGAGAAGAAGCGAAAGAA
AACGAAAACCAGTAAATCTGTTTTCCATTACTTACAGCGATTCCTGTAAA
AAAATGAAAAGAGATGTGCCGAAAACTGAAAACCATAGTAGCAAAAAAAT
AAAAGAAACAGAAAAAAAGCTCCATAAAAAATCTAAAGAAAAAAGAAAAA
AAGGTCGTCCGAAAAAATCAACAGAATTTTCATTAGAAACTGGAAAAGAA
AAGAAAAAATTAAAGAAAAATAAAAAGAAACATGAAAAAGGAAAAAAGCA
TAAAAAACATAAAAGTAAAAATCCATGGGAAAATGCAGAAAGCAGCGATG
AACATAACAACGATGCTGAAGAAGAGGATGAAGTTTATTTAAATGAAGAA
TCAGAAGGATCAATTAGCATTAAAGAAACATGGGACGATAAACCAGAAAG
CGATTTTGATCCGGATAAAATATCGATCAGCAGTGACGAAGAAACATCGA
AAGCTCGTGGAAGAAATTACTTCCGTCAGAAATCCTACAAGAAAGAAAAG
CACGATATCGATGACAAACCCTGTCAGATATGCTTGAAAAATAATATTCC
CGAAATGATCCTTCTCTGTGATGATTGTGATTTCGGCCATCATGCAATGT
GTTTAAAGCCCTCTTTGATGATTATTCCCGAAGGAGAATGGTTCTGTCCG
AAATGTCAGCACAAGAAATTAATCAATAAGTTATCGGAAAAAATCACCGA
ACTGGAAAAATCAATGGTTAAAAACACAGCAAAAATGCGAATGCAAGAAC
GACTGAATTTTGTGAATATCAGCATGAGTAACATTCTGTCTAAGAGCCAA
GAAAGAAAGCAAATCCAAAAATCATGTTGTGAATCGGAATCGGGTTCTCT
GACGGATTGCAATTCCTCGTCGGGTTCACTGTCCTCCAGTTCCGGTTCCT
ACAACTCCTCGGATAACTCATCGAAATCCGGATCAAAAGCCACACGGACT
CGATATAAATTCCGTGAAACAAGTCGCAAAGAGAACACGAAGTATAATTT
TGAGGAAATCGATAAAATGTTCGATGACGCTCTCGAGCATGACGAGAAAT
ACAAACTATTGAAAAAAGAACAAGAAAGCCGAGATAGGAGGAATTCCGAA
TCCTCTAGAGGTGAAGAATCGGAACCCGAATACGATTACAGTGGGATTGA
ACCGAGGAAGAAATCATCGGGTAAAGATATGGCTAATATTGTCAATGAGG
ACGAGGAGCAGATGCCGGCTCGGCCTATGGTGAAAAAGAAACGGTTAAAG
TATATCAGTGACGAGGATTACGAGGACGATATAAAGGATACGGATTTCAA
GTTGTCGGATCAATCGGATTCAGAGTTGGATGAATATGAATGTCCGGAAG
CAAATGGATCGAATTGTTCCGATGATGATGATGATGATGATTGGGTGGTA
TCGAGAAAACGGGTCACTAGGAAGGCGACCAAGAAAAAGTATAAGCATCG
TTCAGTTTTAGAGAGTTCCGGTGGTTACAGCAGGCCAAGGAGAAACGCAA
CAAGGAACATAAATTATCGAAATATGCTCGGTGATGAAGACGAAGATGAG
GATGAAGAACCTGGTGATAAATCTCCTGAGTATGAATCCGACGATAGCAA
TAGGAAACCGCCACCGGTAGTGTCACGAAAGAAAGACAAGCACTCTGGTC
TAATCAAAAAGAGAATTATTTCAGATTCGGAATATGAGGAAAATTCAAAA
TCGGAATCGATTGCTGATTCTGGTTCAACGGAAAAACTGGAAGTTGTCAA
ACGCAAATTCAAACCCGATCTCAACAGTGATTCAGAAGATGAACAACAGG
TGACAAAGGTTCCATTAATCGATAATGAAGACAATGATGCATCGAATGAT
TACAATAACGATCTGATTATCGATATCAAATCTTCCCCGATATCGAACAT
ACCGATCTATCCCTCACTGGCAATCCTGAACCCGATGCGCGCTAAGGCGG
ATGAAGATGACGACGTGGAGAACGAAGTGGAATCGGAAACCGAGTGTGAT
TTGACAATATCAATGAGTAGCAACCAGGATTTGAACAATCAGAACACGGC
ACCAAAGGTTTAATGGAGCAATGGAATCGATTGGACGGGCAATGTATGTG
AGGTTGTCCTTGTGTGTATATTTATATGTATTTCTCTATCTTACAGTCGT
TATTATTTGACTCATTTTTACATCTGTGAATACTTACTGATTGTAAATTC
TTTGCTGCATTTCACCAACACGTTTTTTGTAAT
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protein sequence of SMED30011300-orf-1

>SMED30011300-orf-1 ID=SMED30011300-orf-1|Name=SMED30011300-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1033bp
MSSLKELPEFASLCSFIQLFGEELNVTLSHCQLSKFLEITDADNVPKIWI
DIHRRLLSRIKYRCSIDKWEGTLKKCLVNVLGYESELANLNGTNYFGISA
ENRAKILNILFDCQFDKNIKFKEKVNLKLISDLRTQPFGSDIHGCIYWLF
VDIDISIIMYKENLEEESFKIVAESLEDLNNILKELSEVDCEKVNLSQLY
SVNSPSDDVDHSRNQSPILDNISGILEKATNKLIPTKMETNDLSVDIKNE
GIDTEIDYSTNEPILDDIQPKSEEILKIETETENDKITTEICTSESMPNE
NLNKNANSCVSPEKSKKKLGRKQKEISPCNEDESNANIGLRRSERKRKPV
NLFSITYSDSCKKMKRDVPKTENHSSKKIKETEKKLHKKSKEKRKKGRPK
KSTEFSLETGKEKKKLKKNKKKHEKGKKHKKHKSKNPWENAESSDEHNND
AEEEDEVYLNEESEGSISIKETWDDKPESDFDPDKISISSDEETSKARGR
NYFRQKSYKKEKHDIDDKPCQICLKNNIPEMILLCDDCDFGHHAMCLKPS
LMIIPEGEWFCPKCQHKKLINKLSEKITELEKSMVKNTAKMRMQERLNFV
NISMSNILSKSQERKQIQKSCCESESGSLTDCNSSSGSLSSSSGSYNSSD
NSSKSGSKATRTRYKFRETSRKENTKYNFEEIDKMFDDALEHDEKYKLLK
KEQESRDRRNSESSRGEESEPEYDYSGIEPRKKSSGKDMANIVNEDEEQM
PARPMVKKKRLKYISDEDYEDDIKDTDFKLSDQSDSELDEYECPEANGSN
CSDDDDDDDWVVSRKRVTRKATKKKYKHRSVLESSGGYSRPRRNATRNIN
YRNMLGDEDEDEDEEPGDKSPEYESDDSNRKPPPVVSRKKDKHSGLIKKR
IISDSEYEENSKSESIADSGSTEKLEVVKRKFKPDLNSDSEDEQQVTKVP
LIDNEDNDASNDYNNDLIIDIKSSPISNIPIYPSLAILNPMRAKADEDDD
VENEVESETECDLTISMSSNQDLNNQNTAPKV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
Vocabulary: INTERPRO
TermDefinition
IPR028938Rsf-1
IPR011011Znf_FYVE_PHD
IPR001965Znf_PHD
IPR019787Znf_PHD-finger
IPR013083Znf_RING/FYVE/PHD
IPR019786Zinc_finger_PHD-type_CS
Vocabulary: molecular function
TermDefinition
GO:0008270zinc ion binding
GO:0005515protein binding
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
Vocabulary: cellular component
TermDefinition
GO:0031213RSF complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 570..590
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 362..380
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 922..948
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 639..667
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 381..398
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1009..1031
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 698..759
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 399..413
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 296..312
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 836..850
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 772..786
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 446..461
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 414..434
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 296..345
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 467..500
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 772..807
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 855..870
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 995..1031
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 639..659
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 314..329
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 871..912
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 362..505
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 819..956
NoneNo IPR availablePANTHERPTHR10615HISTONE ACETYLTRANSFERASEcoord: 270..948
NoneNo IPR availablePANTHERPTHR10615HISTONE ACETYLTRANSFERASEcoord: 6..212
NoneNo IPR availableCDDcd15543PHD_RSF1coord: 519..564
e-value: 1.31855E-23
score: 92.3324
IPR001965Zinc finger, PHD-typeSMARTSM00249PHD_3coord: 519..565
e-value: 7.2E-10
score: 48.8
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 483..571
e-value: 3.3E-16
score: 61.0
IPR019787Zinc finger, PHD-fingerPFAMPF00628PHDcoord: 520..566
e-value: 1.0E-9
score: 38.1
IPR019787Zinc finger, PHD-fingerPROSITEPS50016ZF_PHD_2coord: 517..567
score: 9.623
IPR028938Remodeling and spacing factor 1PANTHERPTHR10615:SF156REMODELING AND SPACING FACTOR 1coord: 6..212
IPR028938Remodeling and spacing factor 1PANTHERPTHR10615:SF156REMODELING AND SPACING FACTOR 1coord: 270..948
IPR019786Zinc finger, PHD-type, conserved sitePROSITEPS01359ZF_PHD_1coord: 520..564
IPR011011Zinc finger, FYVE/PHD-typeSUPERFAMILYSSF57903FYVE/PHD zinc fingercoord: 512..569