Protein kinase domain-containing protein

Overview


Name	Protein kinase domain-containing protein
Smed ID	SMED30011294
Length (bp)	1216

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Protein kinase domain-containing protein (SMED30011294) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein kinase domain-containing protein (SMED30011294) in cells (dots) of each of the 12 neoblast clusters.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30011294

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 12

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30011294	SMESG000041899.1 SMESG000031064.1	SmedASXL_009246	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
pharynx	SMED30011294	SMESG000041899.1 SMESG000031064.1	dd_Smed_v4_8347_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
protonephridia	SMED30011294	SMESG000041899.1 SMESG000031064.1	dd_Smed_v4_8347_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30011294	SMESG000041899.1 SMESG000031064.1	dd_Smed_v4_8347_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30011294	SMESG000041899.1 SMESG000031064.1	dd_Smed_v4_8347_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30011294	SMESG000041899.1 SMESG000031064.1	dd_Smed_v4_8347_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30011294	SMESG000041899.1 SMESG000031064.1	dd_Smed_v4_8347_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30011294	SMESG000041899.1 SMESG000031064.1	Contig49219	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30011294	SMESG000041899.1 SMESG000031064.1	Contig49219	newmark_ests	PMID:29674431 Fincher et al., 2018
head region	SMED30011294	SMESG000041899.1 SMESG000031064.1	dd_Smed_v6_8347_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
epidermis	SMED30011294	SMESG000041899.1 SMESG000031064.1	dd_Smed_v4_8347_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
Category 4 cell	SMED30011294	SMESG000041899.1 SMESG000031064.1	dd_Smed_v4_8347_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: NEK7 (NIMA related kinase 7 [Source:HGNC Symbol;Acc:HGNC:13386])

HSP 1 Score: 425.631 bits (1093), Expect = 5.842e-149
Identity = 197/276 (71.38%), Postives = 230/276 (83.33%), Query Frame = 3

Query:  114 PNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKT 941
            P+  Y +L+ F + K+IG+GQFSEV+RA        VALKKVQI+++MD KAR DCIKEIDLLKQL+HPNVIK  ASF+E+NELNIVLELADAGDLS+MIKHF+++ +L+PE+T+WKYFVQ+CS L HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLP++ YS ELR LV+ CIN DP  RP+++Y+Y VAK MH  T
Sbjct:   24 PDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACT 299

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Query:  114 PNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKT 941
            P+  Y +L+ F + K+IG+GQFSEV+RA        VALKKVQI+++MD KAR DCIKEIDLLKQL+HPNVIK  ASF+E+NELNIVLELADAGDLS+MIKHF+++ +L+PE+T+WKYFVQ+CS L HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLP++ YS ELR LV+ CIN DP  RP+++Y+Y VAK MH  T
Sbjct:   24 PDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACT 299

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BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: NEK6 (NIMA related kinase 6 [Source:HGNC Symbol;Acc:HGNC:7749])

HSP 1 Score: 416.001 bits (1068), Expect = 4.427e-145
Identity = 196/279 (70.25%), Postives = 230/279 (82.44%), Query Frame = 3

Query:  102 PQNDPN--SPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMH 932
            PQ  PN  S   SL+ F + K+IG+GQFSEV++A      + VALKKVQI+EMMD KARQDC+KEI LLKQL+HPN+IK L SF+E+NELNIVLELADAGDLSQMIK+F+++ +L+PE+T+WKYFVQ+CS + HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LC+KI+ CDYPPLP   YS +LR LVS CI  DP+ RP+I Y++ VAK+MH
Sbjct:   29 PQRHPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPDIGYVHQVAKQMH 307

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Query:  102 PQNDPN--SPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMH 932
            PQ  PN  S   SL+ F + K+IG+GQFSEV++A      + VALKKVQI+EMMD KARQDC+KEI LLKQL+HPN+IK L SF+E+NELNIVLELADAGDLSQMIK+F+++ +L+PE+T+WKYFVQ+CS + HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LC+KI+ CDYPPLP   YS +LR LVS CI  DP+ RP+I Y++ VAK+MH
Sbjct:   29 PQRHPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPDIGYVHQVAKQMH 307

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Query:  102 PQNDPN--SPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMH 932
            PQ  PN  S   SL+ F + K+IG+GQFSEV++A      + VALKKVQI+EMMD KARQDC+KEI LLKQL+HPN+IK L SF+E+NELNIVLELADAGDLSQMIK+F+++ +L+PE+T+WKYFVQ+CS + HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LC+KI+ CDYPPLP   YS +LR LVS CI  DP+ RP+I Y++ VAK+MH
Sbjct:   29 PQRHPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPDIGYVHQVAKQMH 307

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BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: nekl-3 (Serine/threonine-protein kinase nekl-3 [Source:UniProtKB/Swiss-Prot;Acc:G5EFM9])

HSP 1 Score: 389.808 bits (1000), Expect = 2.911e-135
Identity = 187/275 (68.00%), Postives = 222/275 (80.73%), Query Frame = 3

Query:  108 NDPNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMH 932
            +DP     SL  F + K+IGKGQFSEV+RA+    +  VALKK+Q++EM+D KARQDC+KEIDLLKQL+H NVI+  ASF++NN+LNIVLELA+AGD+S+MIKHF++  +L+PEKTIWKYFVQ+   L HMHSKRIMHRDIKPANVFIT  G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERI E  YN  SD+WS GCLLYEMAALQSPFYGDKM L  LCKKI+ C+YPPLPA+IYS +LR LVS+CI  + + RPE S +  VA+ M+
Sbjct:   11 DDPPPDKLSLELFIIEKKIGKGQFSEVFRAQCTWVDLHVALKKIQVFEMVDQKARQDCLKEIDLLKQLNHVNVIRYYASFIDNNQLNIVLELAEAGDMSRMIKHFKKGGRLIPEKTIWKYFVQLARALAHMHSKRIMHRDIKPANVFITGNGIVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIQESGYNFKSDLWSTGCLLYEMAALQSPFYGDKMNLYSLCKKIENCEYPPLPADIYSTQLRDLVSRCILPEASKRPETSEVLQVAEHMN 285

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Query:  108 NDPNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMH 932
            +DP     SL  F + K+IGKGQFSEV+RA+    +  VALKK+Q++EM+D KARQDC+KEIDLLKQL+H NVI+  ASF++NN+LNIVLELA+AGD+S+MIKHF++  +L+PEKTIWKYFVQ+   L HMHSKRIMHRDIKPANVFIT  G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERI E  YN  SD+WS GCLLYEMAALQSPFYGDKM L  LCKKI+ C+YPPLPA+IYS +LR LVS+CI  + + RPE S +  VA+ M+
Sbjct:   11 DDPPPDKLSLELFIIEKKIGKGQFSEVFRAQCTWVDLHVALKKIQVFEMVDQKARQDCLKEIDLLKQLNHVNVIRYYASFIDNNQLNIVLELAEAGDMSRMIKHFKKGGRLIPEKTIWKYFVQLARALAHMHSKRIMHRDIKPANVFITGNGIVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIQESGYNFKSDLWSTGCLLYEMAALQSPFYGDKMNLYSLCKKIENCEYPPLPADIYSTQLRDLVSRCILPEASKRPETSEVLQVAEHMN 285

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BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: nekl-1 (NEK (NEver in mitosis Kinase) Like [Source:UniProtKB/TrEMBL;Acc:A0A061AD48])

HSP 1 Score: 181.415 bits (459), Expect = 4.785e-50
Identity = 93/273 (34.07%), Postives = 156/273 (57.14%), Query Frame = 3

Query:   81 MSNNIIVPQNDPNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSST--NDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRP 893
            ++N I++   +P +     +++  ++ +GKG F        +  + +V +K++ +Y++ D+  R+  + E+ LL +++HPN+I    SF E   L I +E AD G L+QM+    R   L+ E+ I    +Q+CS + ++H   ++HRD+K ANVF+T    VK+GD G+ +   + T    A+++VGTPYY+SPE     +YN  SD+W+LGC+LYEM  L+  F GD   L  L   I  C Y P+    YS E++ ++ + +  DP  RP
Sbjct:  113 INNEIMITNPNPRATSAQ-NRYERIRTVGKGAFGSAVLYRRREDSSLVIIKEINMYDL-DSSQRRLALNEVSLLSRIEHPNIIAYYDSFEEEGVLMIEMEYADGGTLAQMLS---RTQNLLDEEQIGDMMIQMCSAVAYLHENSVLHRDLKTANVFLTRDSFVKIGDFGISKIMGTETLAQGAKTVVGTPYYISPEMCSGVSYNEKSDMWALGCILYEMCCLKKAFEGD--NLPALVNSIMTCAYTPVKGP-YSAEMKMVIRELLQLDPQKRP 377

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BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: nekl-1 (NEK (NEver in mitosis Kinase) Like [Source:UniProtKB/TrEMBL;Acc:A0A061AD48])

HSP 1 Score: 181.8 bits (460), Expect = 4.840e-50
Identity = 93/273 (34.07%), Postives = 156/273 (57.14%), Query Frame = 3

Query:   81 MSNNIIVPQNDPNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSST--NDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRP 893
            ++N I++   +P +     +++  ++ +GKG F        +  + +V +K++ +Y++ D+  R+  + E+ LL +++HPN+I    SF E   L I +E AD G L+QM+    R   L+ E+ I    +Q+CS + ++H   ++HRD+K ANVF+T    VK+GD G+ +   + T    A+++VGTPYY+SPE     +YN  SD+W+LGC+LYEM  L+  F GD   L  L   I  C Y P+    YS E++ ++ + +  DP  RP
Sbjct:  151 INNEIMITNPNPRATSAQ-NRYERIRTVGKGAFGSAVLYRRREDSSLVIIKEINMYDL-DSSQRRLALNEVSLLSRIEHPNIIAYYDSFEEEGVLMIEMEYADGGTLAQMLS---RTQNLLDEEQIGDMMIQMCSAVAYLHENSVLHRDLKTANVFLTRDSFVKIGDFGISKIMGTETLAQGAKTVVGTPYYISPEMCSGVSYNEKSDMWALGCILYEMCCLKKAFEGD--NLPALVNSIMTCAYTPVKGP-YSAEMKMVIRELLQLDPQKRP 415

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BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: nekl-2 (Serine/threonine-protein kinase nekl-2 [Source:UniProtKB/Swiss-Prot;Acc:O01775])

HSP 1 Score: 157.147 bits (396), Expect = 4.258e-44
Identity = 90/268 (33.58%), Postives = 150/268 (55.97%), Query Frame = 3

Query:  135 LSKFNVVKRIGKGQFSEVW--RAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFR-------RKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQV-KLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYM 908
            +  +  V+ +G+G F   W  R +  A+++ V +K +  + M + K       E++LLK++ HP +I  + SF+ +N+L IV++ A+ G L ++I   R       R+Y   PEKT+  YF QI   LNHMH K I+HRD+KP N+ +     V KL D G+ +   + +  A +++GTP Y+SPE    + YN  SD+WSLGC+LYE+  L+  F G+ +  + +  KI      PL  ++ S +++ LV   +    + RP++S +
Sbjct:    1 MDNYEKVRVVGRGAFGVCWLCRGKNDASHQKVIIKLINTHGMTE-KEENSIQSEVNLLKKVQHPLIIGYIDSFIMDNQLGIVMQYAEGGTLERLINDQRAIKDSNMREY--FPEKTVLDYFTQILIALNHMHQKNIVHRDLKPQNILMNRRKTVLKLSDFGISKELGTKSA-ASTVIGTPNYLSPEICESRPYNQKSDMWSLGCVLYELLQLERAFDGENLPAIVM--KITRSKQNPLGDHV-SNDVKMLVENLLKTHTDKRPDVSQL 261

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BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Nek2 (gene:FBgn0029970 transcript:FBtr0071142)

HSP 1 Score: 179.489 bits (454), Expect = 1.214e-49
Identity = 96/262 (36.64%), Postives = 147/262 (56.11%), Query Frame = 3

Query:  132 SLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFV--ENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSK----RIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEI 899
            +L  + V+  +G G F   ++   K+T E+ A K +  Y+ +D       + EI +L+QL HPN+++     V  E   + IV+E    GDL+Q+++  R + Q   E  IW+   Q+C  L   H+K     I+HRDIKPAN+F+ + G  KLGD GL R      + A S VGTP+YMSPE +  + Y+  SD+W++GCL+YEM AL+ PF G       L +KI   ++  +PA IYS +L+ +++  +  D   RP I
Sbjct:   15 TLQDYEVLAVMGNGSFGTCYKVRDKSTGELFAWKGMN-YDELDEAKCDALVSEISVLRQLQHPNIVQYYHHLVNREAKSVYIVMECCAGGDLAQIVQRARSQRQRFEEPYIWRVLFQLCRALQVCHNKIPNGTILHRDIKPANIFLDAAGNAKLGDFGLARMLRRDQSFAASFVGTPHYMSPELVKGRKYDRKSDVWAVGCLVYEMCALRPPFRG--RAFDQLSEKIAQGEFSRIPA-IYSTDLQEIIAFMLAVDHEQRPGI 272

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BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: niki (gene:FBgn0045980 transcript:FBtr0084737)

HSP 1 Score: 175.252 bits (443), Expect = 6.207e-48
Identity = 92/256 (35.94%), Postives = 148/256 (57.81%), Query Frame = 3

Query:  135 LSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEIS 902
            L+ +  V+ +G+G F        K+    +  K++ + E+     R   + E+D+  +L HPN++  L SF+++N L I +E AD G L+Q+I   + K    PE+ I   F QI S +N+MHS+ I+HRD+K ANVF+   G VK+GD G+ +  ++  + AQ+++GTPYY SPE    + Y+  SDIW+LGC+L EM  L+  F    ++  +L  KI   +Y P+P+  Y+  LR+L+S  +  +   RP  S
Sbjct:  102 LANYEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSEL-SPPGRDLAMNEVDVFSKLHHPNIVSYLGSFIKDNTLLIEMEYADGGTLAQIIAERQGKLHF-PERYIIAVFEQISSAINYMHSENILHRDLKTANVFLNRRGIVKIGDFGISKIMNTKIH-AQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCILGEMCCLKKTFAASNLS--ELVTKIMAGNYTPVPSG-YTSGLRSLMSNLLQVEAPRRPTAS 351

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BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: GckIII (gene:FBgn0266465 transcript:FBtr0083399)

HSP 1 Score: 146.362 bits (368), Expect = 3.117e-38
Identity = 85/251 (33.86%), Postives = 133/251 (52.99%), Query Frame = 3

Query:  144 FNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYG-DKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRP 893
            F   +RIGKG F EV++     T ++VA+K + + E  D     D  +EI +L Q D P V K   SF++  +L I++E    G    ++K          E  I     ++  GL+++HS+R +HRDIK ANV ++  G VKL D G+    +++T+   + VGTP++M+PE I +  Y+  +DIWSLG    E+A  + P      M ++ L  K    + PP     Y++  +  V  C+NKDP +RP
Sbjct:   13 FTKQERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEI--DDIQQEIMVLSQCDSPYVTKYYGSFLKGTKLWIIMEYLGGGSALDLMKAGS-----FEEMHIGIILREVLKGLDYLHSERKLHRDIKAANVLLSEQGDVKLADFGVAGQLTNTTSKRNTFVGTPFWMAPEVIKQSQYDAKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPK----NNPPQLTGSYTKSFKDFVEACLNKDPENRP 252

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BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Tao (gene:FBgn0031030 transcript:FBtr0309237)

HSP 1 Score: 133.65 bits (335), Expect = 7.952e-34
Identity = 85/253 (33.60%), Postives = 125/253 (49.41%), Query Frame = 3

Query:  144 FNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERI---HEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRP 893
            F  ++ IG G F  V+ A    T EIVA+KK+        +  QD +KEI  L+QL+HPN I+    ++  +   +V+E    G  S +I+  ++      E  I    + + SGL+++HS   +HRDIK  N+ +T  G VKL D G           A S VGTPY+M+PE I    E  Y+   D+WSLG    E+A  + P++   M  +     I   + P LP N +S    + V  C+ K P  RP
Sbjct:   27 FEDLREIGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQEKWQDILKEIRFLRQLNHPNTIEYKGCYLRESTAWLVMEYC-VGSASDIIEVHKKPLH---EDEIAAICLGVLSGLSYLHSLGRIHRDIKAGNILLTDNGVVKLADFGSAAIKCP----ANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPYF--NMNAMSALYHIAQNESPTLPKNDWSDAFCSFVELCLKKMPAERP 269

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BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Tao (gene:FBgn0031030 transcript:FBtr0336692)

HSP 1 Score: 133.265 bits (334), Expect = 9.060e-34
Identity = 85/253 (33.60%), Postives = 125/253 (49.41%), Query Frame = 3

Query:  144 FNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERI---HEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRP 893
            F  ++ IG G F  V+ A    T EIVA+KK+        +  QD +KEI  L+QL+HPN I+    ++  +   +V+E    G  S +I+  ++      E  I    + + SGL+++HS   +HRDIK  N+ +T  G VKL D G           A S VGTPY+M+PE I    E  Y+   D+WSLG    E+A  + P++   M  +     I   + P LP N +S    + V  C+ K P  RP
Sbjct:   27 FEDLREIGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQEKWQDILKEIRFLRQLNHPNTIEYKGCYLRESTAWLVMEYC-VGSASDIIEVHKKPLH---EDEIAAICLGVLSGLSYLHSLGRIHRDIKAGNILLTDNGVVKLADFGSAAIKCP----ANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPYF--NMNAMSALYHIAQNESPTLPKNDWSDAFCSFVELCLKKMPAERP 269

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BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: nek7 (NIMA-related kinase 7 [Source:ZFIN;Acc:ZDB-GENE-040801-136])

HSP 1 Score: 430.639 bits (1106), Expect = 2.990e-151
Identity = 199/271 (73.43%), Postives = 230/271 (84.87%), Query Frame = 3

Query:  126 YGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEK 938
            Y SL+ F + K+IG+GQFSEV+RA     + IVALKK+QI+++MD KARQDCIKEIDLLKQL+HPNVIK  ASF+E NELNIVLELADAGDLSQMI+HF+++ +L+PEKT+WKYFVQ+CS L HMHS+RIMHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLP++ YS+ELR LV  CIN DP  RP+I+Y+Y +AK MH +
Sbjct:   24 YNSLANFAIEKKIGRGQFSEVYRATYVLDHTIVALKKIQIFDLMDAKARQDCIKEIDLLKQLNHPNVIKYHASFIEENELNIVLELADAGDLSQMIRHFKKQRRLIPEKTVWKYFVQLCSALEHMHSRRIMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSQELRKLVDMCINPDPEKRPDITYVYSMAKHMHGR 294

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BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: nek6 (NIMA-related kinase 6 [Source:ZFIN;Acc:ZDB-GENE-040724-133])

HSP 1 Score: 405.986 bits (1042), Expect = 5.805e-142
Identity = 187/262 (71.37%), Postives = 218/262 (83.21%), Query Frame = 3

Query:  144 FNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEM 929
            F + K+IG+GQFSEV+RA     N+ VALKKVQI+EMMD KARQDC+KEIDLLKQL+HPNVIK L SF+ NNELNIVLELA AGDLSQMI HF++K +L+PE+TIWKYFVQ+CS L HMHS+R+MHRDIKPANVFIT+ G+VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAAL SPFY DKM L+ LC KI+ C+YPPLP   YS++ R LVS CIN +P+ RP+IS++   + +M
Sbjct:    2 FLIEKKIGRGQFSEVYRATCLLNNQKVALKKVQIFEMMDAKARQDCVKEIDLLKQLNHPNVIKYLDSFIANNELNIVLELASAGDLSQMIMHFKKKRRLIPERTIWKYFVQLCSALEHMHSRRVMHRDIKPANVFITASGEVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALHSPFYSDKMNLLSLCHKIEQCEYPPLPTEHYSQKFRDLVSMCINPEPDQRPDISFVLQFSTQM 263

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BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: nek6 (NIMA-related kinase 6 [Source:ZFIN;Acc:ZDB-GENE-040724-133])

HSP 1 Score: 330.102 bits (845), Expect = 2.344e-112
Identity = 160/267 (59.93%), Postives = 190/267 (71.16%), Query Frame = 3

Query:  129 GSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEM 929
             +LS F + K+IG+GQFSEV+RA     N+ VALKKVQI+EMMD KARQDC+KEIDLLKQL+HPNVIK L SF+ NNELNIVLELA AGDLSQMI HF++K +L+PE+TIWKYFVQ+CS L HMHS+R+MHR                                    VGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAAL SPFY DKM L+ LC KI+ C+YPPLP   YS++ R LVS CIN +P+ RP+IS++   + +M
Sbjct:   18 SNLSNFLIEKKIGRGQFSEVYRATCLLNNQKVALKKVQIFEMMDAKARQDCVKEIDLLKQLNHPNVIKYLDSFIANNELNIVLELASAGDLSQMIMHFKKKRRLIPERTIWKYFVQLCSALEHMHSRRVMHR------------------------------------VGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALHSPFYSDKMNLLSLCHKIEQCEYPPLPTEHYSQKFRDLVSMCINPEPDQRPDISFVLQFSTQM 248

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BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: nek1 (NIMA-related kinase 1 [Source:ZFIN;Acc:ZDB-GENE-040730-1])

HSP 1 Score: 191.815 bits (486), Expect = 5.020e-58
Identity = 101/270 (37.41%), Postives = 160/270 (59.26%), Query Frame = 3

Query:  135 LSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYG---VAKEMHE 935
            + K+  +K+IG+G F +    + +       +K++ I   M  K RQ+  KE+ +L  + HPN+++   SF E+  L IV++  + GDL + I + R    L PE+ I  +FVQIC  L H+H ++I+HRDIK  N+F+T  G V+LGD G+ R  +S+   A++ +GTPYY+SPE    + YN  SDIW+LGC+LYEM  L+  F    M   +L  KI    YPP+  + YS +LR+L++Q   ++P  RP +S +     +A+ +H+
Sbjct:    1 MDKYERLKKIGEGSFGKAILVKSRTDGRQYVIKEIGI-SRMSNKERQESRKEVAVLANMSHPNIVQYKESFEESGCLYIVMDYCEGGDLFKKINNQRG--SLFPEEQILDWFVQICLALKHVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKPYNNKSDIWALGCVLYEMCTLKHAFEAGNMK--NLVLKIIRGSYPPVSIH-YSPDLRSLLAQLFKRNPRERPSVSTILDKPFLARRIHK 264

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BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: CABZ01040556.1 (NIMA related kinase 3 [Source:NCBI gene;Acc:100536894])

HSP 1 Score: 168.318 bits (425), Expect = 1.962e-47
Identity = 93/259 (35.91%), Postives = 143/259 (55.21%), Query Frame = 3

Query:  135 LSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQI--YEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGD--KMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEI 899
            + +++VV+ IG+G F      +     +   +K++++   E    K+R + +    LL ++ HPN++    SF  +  L IV+E    GDL Q I+   R   L  E+ I K+F Q+C G  H+H KR++HRD+K  N+F+T  G VK+GD G     +S+   AQ+ VGTPYY+SPE    + YN  SD+WSLGC+LYE+  LQ PF     K  ++ +C+      Y PLP++ +  EL  L+      +P  RP I
Sbjct:    1 MDQYSVVRVIGEGSFGRALLVQPIHEEKHYVMKEIRLPKAESGMKKSRSEAV----LLSKMKHPNIVAFRDSFEADGHLYIVMEFCSGGDLMQRIRQQNR--LLFSEEQILKWFAQMCLGTKHIHDKRVLHRDLKSKNIFLTDSGTVKVGDFGSACSLNSAKAYAQTYVGTPYYVSPEIWDNKPYNNKSDVWSLGCVLYELCTLQHPFQARSWKSLILQVCRG----SYAPLPSH-FPYELHYLIKHMFKTNPKDRPSI 248

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BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: nek7 (NIMA-related kinase 7 [Source:NCBI gene;Acc:780029])

HSP 1 Score: 424.091 bits (1089), Expect = 1.185e-148
Identity = 198/276 (71.74%), Postives = 228/276 (82.61%), Query Frame = 3

Query:  114 PNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKT 941
            P+  Y  L+ F + K IG+GQFSEV+RA        VALKKVQI+++MD KAR DCIKEIDLLKQL+HPNVIK  ASF+E+NELNIVLELADAGDLS+MIKHF+++ +L+PEKT+WKYFVQ+CS L HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLP++ YS ELR LV+ CIN DP  RP+++Y+Y VAK MH  T
Sbjct:   15 PDMGYNILANFQIGKMIGRGQFSEVYRATCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPEKTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRMLVNTCINPDPEKRPDVTYVYEVAKRMHALT 290

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BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: nek7 (NIMA-related kinase 7 [Source:NCBI gene;Acc:780029])

HSP 1 Score: 424.476 bits (1090), Expect = 1.245e-148
Identity = 198/276 (71.74%), Postives = 228/276 (82.61%), Query Frame = 3

Query:  114 PNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKT 941
            P+  Y  L+ F + K IG+GQFSEV+RA        VALKKVQI+++MD KAR DCIKEIDLLKQL+HPNVIK  ASF+E+NELNIVLELADAGDLS+MIKHF+++ +L+PEKT+WKYFVQ+CS L HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLP++ YS ELR LV+ CIN DP  RP+++Y+Y VAK MH  T
Sbjct:   25 PDMGYNILANFQIGKMIGRGQFSEVYRATCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPEKTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRMLVNTCINPDPEKRPDVTYVYEVAKRMHALT 300

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BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: nek7 (NIMA-related kinase 7 [Source:NCBI gene;Acc:780029])

HSP 1 Score: 424.091 bits (1089), Expect = 1.423e-148
Identity = 198/276 (71.74%), Postives = 228/276 (82.61%), Query Frame = 3

Query:  114 PNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKT 941
            P+  Y  L+ F + K IG+GQFSEV+RA        VALKKVQI+++MD KAR DCIKEIDLLKQL+HPNVIK  ASF+E+NELNIVLELADAGDLS+MIKHF+++ +L+PEKT+WKYFVQ+CS L HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLP++ YS ELR LV+ CIN DP  RP+++Y+Y VAK MH  T
Sbjct:   14 PDMGYNILANFQIGKMIGRGQFSEVYRATCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPEKTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRMLVNTCINPDPEKRPDVTYVYEVAKRMHALT 289

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BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: nek7 (NIMA-related kinase 7 [Source:NCBI gene;Acc:780029])

HSP 1 Score: 423.705 bits (1088), Expect = 2.611e-148
Identity = 198/276 (71.74%), Postives = 228/276 (82.61%), Query Frame = 3

Query:  114 PNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKT 941
            P+  Y  L+ F + K IG+GQFSEV+RA        VALKKVQI+++MD KAR DCIKEIDLLKQL+HPNVIK  ASF+E+NELNIVLELADAGDLS+MIKHF+++ +L+PEKT+WKYFVQ+CS L HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLP++ YS ELR LV+ CIN DP  RP+++Y+Y VAK MH  T
Sbjct:   24 PDMGYNILANFQIGKMIGRGQFSEVYRATCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPEKTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRMLVNTCINPDPEKRPDVTYVYEVAKRMHALT 299

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BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: nek7 (NIMA-related kinase 7 [Source:NCBI gene;Acc:780029])

HSP 1 Score: 422.935 bits (1086), Expect = 5.750e-148
Identity = 198/276 (71.74%), Postives = 228/276 (82.61%), Query Frame = 3

Query:  114 PNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKT 941
            P+  Y  L+ F + K IG+GQFSEV+RA        VALKKVQI+++MD KAR DCIKEIDLLKQL+HPNVIK  ASF+E+NELNIVLELADAGDLS+MIKHF+++ +L+PEKT+WKYFVQ+CS L HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLP++ YS ELR LV+ CIN DP  RP+++Y+Y VAK MH  T
Sbjct:   25 PDMGYNILANFQIGKMIGRGQFSEVYRATCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPEKTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRMLVNTCINPDPEKRPDVTYVYEVAKRMHALT 300

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BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Nek7 (NIMA (never in mitosis gene a)-related expressed kinase 7 [Source:MGI Symbol;Acc:MGI:1890645])

HSP 1 Score: 425.631 bits (1093), Expect = 3.019e-149
Identity = 198/276 (71.74%), Postives = 231/276 (83.70%), Query Frame = 3

Query:  114 PNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKT 941
            P+  Y +L+ F + K+IG+GQFSEV+RA        VALKKVQI+++MD KAR DCIKEIDLLKQL+HPNVIK  ASF+E+NELNIVLELADAGDLS+MIKHF+++ +L+PE+T+WKYFVQ+CS L+HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLP++ YS ELR LV+ CIN DP  RP+I+Y+Y VAK MH  T
Sbjct:   24 PDMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHACT 299

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Query:  114 PNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKT 941
            P+  Y +L+ F + K+IG+GQFSEV+RA        VALKKVQI+++MD KAR DCIKEIDLLKQL+HPNVIK  ASF+E+NELNIVLELADAGDLS+MIKHF+++ +L+PE+T+WKYFVQ+CS L+HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLP++ YS ELR LV+ CIN DP  RP+I+Y+Y VAK MH  T
Sbjct:   24 PDMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHACT 299

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BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Nek6 (NIMA (never in mitosis gene a)-related expressed kinase 6 [Source:MGI Symbol;Acc:MGI:1891638])

HSP 1 Score: 413.305 bits (1061), Expect = 4.367e-144
Identity = 195/279 (69.89%), Postives = 230/279 (82.44%), Query Frame = 3

Query:  102 PQNDPN--SPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMH 932
            PQ  PN  S   SL+ F + K+IG+GQFSEV++A      + VALKKVQI+EMMD KARQDC+KEI LLKQL+HPN+IK L SF+E+NELNIVLELADAGDLSQMIK+F+++ +L+PE+T+WKYFVQ+CS + HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LC+KI+ CDYPPLP   YS +LR LVS CI  DP+ RP+I Y++ VA++MH
Sbjct:   29 PQRLPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCIYPDPDHRPDIVYVHQVARQMH 307

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Query:  102 PQNDPN--SPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMH 932
            PQ  PN  S   SL+ F + K+IG+GQFSEV++A      + VALKKVQI+EMMD KARQDC+KEI LLKQL+HPN+IK L SF+E+NELNIVLELADAGDLSQMIK+F+++ +L+PE+T+WKYFVQ+CS + HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LC+KI+ CDYPPLP   YS +LR LVS CI  DP+ RP+I Y++ VA++MH
Sbjct:   29 PQRLPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCIYPDPDHRPDIVYVHQVARQMH 307

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BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Nek6 (NIMA (never in mitosis gene a)-related expressed kinase 6 [Source:MGI Symbol;Acc:MGI:1891638])

HSP 1 Score: 409.068 bits (1050), Expect = 1.077e-142
Identity = 188/265 (70.94%), Postives = 223/265 (84.15%), Query Frame = 3

Query:  138 SKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMH 932
            + F + K+IG+GQFSEV++A      + VALKKVQI+EMMD KARQDC+KEI LLKQL+HPN+IK L SF+E+NELNIVLELADAGDLSQMIK+F+++ +L+PE+T+WKYFVQ+CS + HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LC+KI+ CDYPPLP   YS +LR LVS CI  DP+ RP+I Y++ VA++MH
Sbjct:   32 TDFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCIYPDPDHRPDIVYVHQVARQMH 296

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BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9ES74|NEK7_MOUSE (Serine/threonine-protein kinase Nek7 OS=Mus musculus OX=10090 GN=Nek7 PE=1 SV=1)

HSP 1 Score: 425.631 bits (1093), Expect = 2.112e-148
Identity = 198/276 (71.74%), Postives = 231/276 (83.70%), Query Frame = 3

Query:  114 PNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKT 941
            P+  Y +L+ F + K+IG+GQFSEV+RA        VALKKVQI+++MD KAR DCIKEIDLLKQL+HPNVIK  ASF+E+NELNIVLELADAGDLS+MIKHF+++ +L+PE+T+WKYFVQ+CS L+HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLP++ YS ELR LV+ CIN DP  RP+I+Y+Y VAK MH  T
Sbjct:   24 PDMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHACT 299

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BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8TDX7|NEK7_HUMAN (Serine/threonine-protein kinase Nek7 OS=Homo sapiens OX=9606 GN=NEK7 PE=1 SV=1)

HSP 1 Score: 425.631 bits (1093), Expect = 2.806e-148
Identity = 197/276 (71.38%), Postives = 230/276 (83.33%), Query Frame = 3

Query:  114 PNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKT 941
            P+  Y +L+ F + K+IG+GQFSEV+RA        VALKKVQI+++MD KAR DCIKEIDLLKQL+HPNVIK  ASF+E+NELNIVLELADAGDLS+MIKHF+++ +L+PE+T+WKYFVQ+CS L HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLP++ YS ELR LV+ CIN DP  RP+++Y+Y VAK MH  T
Sbjct:   24 PDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACT 299

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BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|D3ZBE5|NEK7_RAT (Serine/threonine-protein kinase Nek7 OS=Rattus norvegicus OX=10116 GN=Nek7 PE=2 SV=1)

HSP 1 Score: 425.246 bits (1092), Expect = 3.062e-148
Identity = 198/276 (71.74%), Postives = 231/276 (83.70%), Query Frame = 3

Query:  114 PNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKT 941
            P+  Y +L+ F + K+IG+GQFSEV+RA        VALKKVQI+++MD KAR DCIKEIDLLKQL+HPNVIK  ASF+E+NELNIVLELADAGDLS+MIKHF+++ +L+PE+T+WKYFVQ+CS L+HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLP++ YS ELR LV+ CIN DP  RP+I+Y+Y VAK MH  T
Sbjct:   24 PDMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHACT 299

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BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|P59895|NEK6_RAT (Serine/threonine-protein kinase Nek6 OS=Rattus norvegicus OX=10116 GN=Nek6 PE=1 SV=1)

HSP 1 Score: 417.157 bits (1071), Expect = 6.752e-145
Identity = 197/279 (70.61%), Postives = 230/279 (82.44%), Query Frame = 3

Query:  102 PQNDPN--SPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMH 932
            PQ  PN  S   SL+ F + K+IG+GQFSEV++A      + VALKKVQI+EMMD KARQDC+KEI LLKQL+HPN+IK L SF+E+NELNIVLELADAGDLSQMIK+F+++ +L+PE+T+WKYFVQ+CS + HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LC+KI+ CDYPPLP   YS +LR LVS CI  DPN RP+I Y++ VAK+MH
Sbjct:   29 PQRHPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCIYPDPNHRPDIEYVHQVAKQMH 307

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BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|A2BD05|NEK6_PIG (Serine/threonine-protein kinase Nek6 OS=Sus scrofa OX=9823 GN=NEK6 PE=3 SV=1)

HSP 1 Score: 416.387 bits (1069), Expect = 1.435e-144
Identity = 196/279 (70.25%), Postives = 230/279 (82.44%), Query Frame = 3

Query:  102 PQNDPN--SPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMH 932
            PQ  PN  S   SL+ F + K+IG+GQFSEV++A      + VALKKVQI+EMMD KARQDC+KEI LLKQL+HPN+IK L SF+E+NELNIVLELADAGDLSQMIK+F+++ +L+PE+T+WKYFVQ+CS + HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LC+KI+ CDYPPLP   YS +LR LVS CI  DPN RP+I Y++ VA++MH
Sbjct:   29 PQRHPNALSFRCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCIYPDPNQRPDIGYVHQVARQMH 307

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BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A1I8GQY4 (Protein kinase domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 467.233 bits (1201), Expect = 9.920e-161
Identity = 218/286 (76.22%), Postives = 247/286 (86.36%), Query Frame = 3

Query:   81 MSNNIIVPQNDPNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEK 938
            M  + +VP +DP + YGSL+KF + K+IGKGQFSEVWRA  +    +VALKKVQI+EMMD KARQDCIKEIDLLKQLDHPNVI+ LASF+ENNELNIVLELADAGDLS+MIKHF+++ +L+PEKTIWKYFVQICSGL+HMHSKRIMHRDIKPANVFIT+ GQVKLGDLGLGRFFSS T +A SLVGTPYYMSPERIHE  YN  SD+WSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLPA+IYS ELR LVS  I   P++RP+ISY+Y VA+ MH K
Sbjct:  108 MDADFVVPNHDPENKYGSLAKFKIDKKIGKGQFSEVWRAICREDECVVALKKVQIFEMMDAKARQDCIKEIDLLKQLDHPNVIRYLASFIENNELNIVLELADAGDLSRMIKHFKKQQRLIPEKTIWKYFVQICSGLDHMHSKRIMHRDIKPANVFITASGQVKLGDLGLGRFFSSKTTNAHSLVGTPYYMSPERIHENGYNFKSDLWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPADIYSSELRDLVSAMIQPSPDARPDISYVYEVAQRMHAK 393

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BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A267EEI4 (Protein kinase domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig024690g2 PE=3 SV=1)

HSP 1 Score: 457.218 bits (1175), Expect = 1.610e-158
Identity = 212/280 (75.71%), Postives = 245/280 (87.50%), Query Frame = 3

Query:   99 VPQNDPNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEK 938
            VP  DP + YGSL KFN+ K+IGKGQFSEVWRA  K    ++ALKKVQI+EMMD KARQDCIKEIDLLKQLDHPNVI+ LASF+ENNELNIVLELADAGDLS+MI+HF+++ +L+PE+TIWKYFVQICSGL+HMHSKRIMHRDIKPANVFIT+ GQVKLGDLGLGRFFSS T +A SLVGTPYYMSPERIHE  YN  SD+WSLGCLLYEMAALQSPFYG++M L  LCKKI+ CDYPPLPA+IYS ELR LV   I+ +P++RP+IS++Y VA++MH K
Sbjct:    2 VPSYDPQNKYGSLDKFNIDKKIGKGQFSEVWRAICKEDGCVIALKKVQIFEMMDAKARQDCIKEIDLLKQLDHPNVIRYLASFIENNELNIVLELADAGDLSRMIRHFKKQQRLIPERTIWKYFVQICSGLDHMHSKRIMHRDIKPANVFITATGQVKLGDLGLGRFFSSKTTNAHSLVGTPYYMSPERIHETGYNFKSDMWSLGCLLYEMAALQSPFYGEQMNLYSLCKKIEQCDYPPLPADIYSNELRELVVTMISSNPDARPDISHVYQVAQDMHAK 281

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BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A267DU22 (Protein kinase domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032178g2 PE=3 SV=1)

HSP 1 Score: 456.833 bits (1174), Expect = 2.140e-158
Identity = 212/280 (75.71%), Postives = 245/280 (87.50%), Query Frame = 3

Query:   99 VPQNDPNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEK 938
            VP  DP + YGSL KFN+ K+IGKGQFSEVWRA  K    ++ALKKVQI+EMMD KARQDCIKEIDLLKQLDHPNVI+ LASF+ENNELNIVLELADAGDLS+MI+HF+++ +L+PE+TIWKYFVQICSGL+HMHSKRIMHRDIKPANVFIT+ GQVKLGDLGLGRFFSS T +A SLVGTPYYMSPERIHE  YN  SD+WSLGCLLYEMAALQSPFYG++M L  LCKKI+ CDYPPLPA+IYS ELR LV   I+ +P++RP+IS++Y VA++MH K
Sbjct:    2 VPSYDPQNKYGSLDKFNIDKKIGKGQFSEVWRAICKEDGCVIALKKVQIFEMMDAKARQDCIKEIDLLKQLDHPNVIRYLASFIENNELNIVLELADAGDLSRMIRHFKKQQRLIPERTIWKYFVQICSGLDHMHSKRIMHRDIKPANVFITATGQVKLGDLGLGRFFSSKTTNAHSLVGTPYYMSPERIHETGYNFKSDMWSLGCLLYEMAALQSPFYGEQMNLYSLCKKIEQCDYPPLPADIYSNELRELVVTMISSNPDARPDISHVYQVAQDMHAK 281

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BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A1S3JQM7 (serine/threonine-protein kinase Nek7 isoform X2 OS=Lingula unguis OX=7574 GN=LOC106175288 PE=3 SV=1)

HSP 1 Score: 455.292 bits (1170), Expect = 1.563e-157
Identity = 213/284 (75.00%), Postives = 241/284 (84.86%), Query Frame = 3

Query:   81 MSNNIIVPQNDPNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMH 932
            M  ++ VP NDPN+ Y +LS F + K+IGKGQFSEVWRA  K     +ALKKVQI+EMMD KARQDCIKEIDLLKQL+HPNVIK LASF+E+NELNIVLELADAGDLS+MIKHF+++ +L+PE+TIWKYF+QICS L HMHSKRIMHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLP++ YS ELR LV+ CIN DP  RP+I+Y+Y VAK+MH
Sbjct:    4 MECDLPVPTNDPNNMYCTLSSFEIDKKIGKGQFSEVWRARCKTDGSAIALKKVQIFEMMDAKARQDCIKEIDLLKQLNHPNVIKYLASFIEDNELNIVLELADAGDLSRMIKHFKKQDRLIPERTIWKYFIQICSSLEHMHSKRIMHRDIKPANVFITAQGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRNLVAVCINPDPEQRPDITYIYEVAKKMH 287

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BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A1I8ICQ9 (Protein kinase domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 460.299 bits (1183), Expect = 1.719e-157
Identity = 218/300 (72.67%), Postives = 248/300 (82.67%), Query Frame = 3

Query:   81 MSNNIIVPQNDPNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKTRVDSAGGSRTSSR 980
            M  + +VP +DP + YGSL+KF + K+IGKGQFSEVWRA  +    +VALKKVQI+EMMD KARQDCIKEIDLLKQLDHPNVI+ LASF+ENNELNIVLELADAGDLS+MIKHF+++ +L+PEKTIWKYFVQICSGL+HMHSKRIMHRDIKPANVFIT+ GQVKLGDLGLGRFFSS T +A SLVGTPYYMSPERIHE  YN  SD+WSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLPA+IYS ELR LVS  I   P++RP+ISY+Y VA      T     G +  S +
Sbjct:  108 MDADFVVPNHDPENKYGSLAKFKIDKKIGKGQFSEVWRAICREDECVVALKKVQIFEMMDAKARQDCIKEIDLLKQLDHPNVIRYLASFIENNELNIVLELADAGDLSRMIKHFKKQQRLIPEKTIWKYFVQICSGLDHMHSKRIMHRDIKPANVFITASGQVKLGDLGLGRFFSSKTTNAHSLVGTPYYMSPERIHENGYNFKSDLWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPADIYSSELRDLVSAMIQPSPDARPDISYVYEVASGCTPSTASSREGHACQSPK 407

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BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: nek7 (NIMA related kinase 7 [Source:NCBI gene;Acc:103046491])

HSP 1 Score: 432.18 bits (1110), Expect = 8.956e-152
Identity = 199/272 (73.16%), Postives = 228/272 (83.82%), Query Frame = 3

Query:  126 YGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKT 941
            Y +LS F + K+IG+GQFSEV+RA     N  VALKK+QI+++MD KARQDCIKEIDLLKQL+HPNVIK  ASF+E NELNIVLELADAGDLS+MIKHF+++ +L+PEKT+WKYFVQ+CS L HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLP++ YS ELR LV  CIN DP  RP+I+Y+Y +AK MH  T
Sbjct:   34 YSTLSNFQIEKKIGRGQFSEVYRARYLINNTAVALKKIQIFDLMDAKARQDCIKEIDLLKQLNHPNVIKYHASFIEENELNIVLELADAGDLSRMIKHFKKQRRLIPEKTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRKLVDMCINPDPERRPDIAYVYNIAKHMHALT 305

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BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: nek6 (NIMA-related kinase 6 [Source:ZFIN;Acc:ZDB-GENE-040724-133])

HSP 1 Score: 407.142 bits (1045), Expect = 4.563e-142
Identity = 188/267 (70.41%), Postives = 223/267 (83.52%), Query Frame = 3

Query:  129 GSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEM 929
             +LS F + K+IG+GQFSEV+RA     N+ VALKKVQI+EMMD K+RQDCIKEIDLLKQL+HPNVIK L SF+E+NELNIVLELADAGDLS MIK+F++K +L+PE+TIWKYFVQ+CS + HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T    SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFY D+M L+ LC+KI+ CDYPPLP   +S +LR+LVS CIN D + RP+I ++   +K+M
Sbjct:   26 SALSNFRIEKKIGRGQFSEVYRATYLLENQQVALKKVQIFEMMDAKSRQDCIKEIDLLKQLNHPNVIKYLDSFIEDNELNIVLELADAGDLSHMIKYFKKKRRLIPERTIWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTVVHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYSDQMNLLSLCQKIEQCDYPPLPPEHFSEKLRSLVSMCINPDADERPDIVFVLQFSKQM 292

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BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: nek7 (NIMA related kinase 7 [Source:NCBI gene;Acc:103046491])

HSP 1 Score: 383.259 bits (983), Expect = 8.263e-133
Identity = 182/272 (66.91%), Postives = 208/272 (76.47%), Query Frame = 3

Query:  126 YGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKT 941
            Y +LS F + K+IG+GQFSEV+RA     N  VALKK+Q                     QL+HPNVIK  ASF+E NELNIVLELADAGDLS+MIKHF+++ +L+PEKT+WKYFVQ+CS L HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLP++ YS ELR LV  CIN DP  RP+I+Y+Y +AK MH  T
Sbjct:   34 YSTLSNFQIEKKIGRGQFSEVYRARYLINNTAVALKKIQ---------------------QLNHPNVIKYHASFIEENELNIVLELADAGDLSRMIKHFKKQRRLIPEKTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRKLVDMCINPDPERRPDIAYVYNIAKHMHALT 284

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BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: nek6 (NIMA-related kinase 6 [Source:ZFIN;Acc:ZDB-GENE-040724-133])

HSP 1 Score: 338.191 bits (866), Expect = 1.106e-115
Identity = 167/284 (58.80%), Postives = 203/284 (71.48%), Query Frame = 3

Query:   81 MSNNIIVPQNDPNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMH 932
            M+NN + PQ  P S +  LS F + K+IG+GQFSEV+RA     N+ VALKKVQI+EMMD K+RQDCIKEIDLLKQL+HPNVIK L SF+E+NELNIVLELADAGDLS MIK+F++K +L+PE+TIWKYFVQ+CS + HMHS+R+MHR                                    VGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFY D+M L+ LC+KI+ CDYPPLP   +S +LR+LVS CIN D + RP+I ++   +K+M 
Sbjct:    1 MANNCVEPQK-PFSLFA-LSNFRIEKKIGRGQFSEVYRATYLLENQQVALKKVQIFEMMDAKSRQDCIKEIDLLKQLNHPNVIKYLDSFIEDNELNIVLELADAGDLSHMIKYFKKKRRLIPERTIWKYFVQLCSAVEHMHSRRVMHR------------------------------------VGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYSDQMNLLSLCQKIEQCDYPPLPPEHFSEKLRSLVSMCINPDADERPDIVFVLQFSKQMQ 246

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BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: nek6 (NIMA-related kinase 6 [Source:ZFIN;Acc:ZDB-GENE-040724-133])

HSP 1 Score: 332.028 bits (850), Expect = 6.510e-113
Identity = 167/270 (61.85%), Postives = 195/270 (72.22%), Query Frame = 3

Query:  129 GSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMP--EKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMH 932
             +LS F + K+IG+GQFSEV+RA     N+ VALKKVQI+EMMD K+RQDCIKEIDLLKQL+HPNVIK L SF+E+NELNIVLELADAGDLS MIK        +P  + T+W                      IKPANVFIT+ G VKLGDLGLGRFFSS T    SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFY D+M L+ LC+KI+ CDYPPLP   +S +LR+LVS CIN D + RP+I ++   +K+M 
Sbjct:   25 SALSNFRIEKKIGRGQFSEVYRATYLLENQQVALKKVQIFEMMDAKSRQDCIKEIDLLKQLNHPNVIKYLDSFIEDNELNIVLELADAGDLSHMIK--------LPSVQTTVWH---------------------IKPANVFITATGVVKLGDLGLGRFFSSKTTVVHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYSDQMNLLSLCQKIEQCDYPPLPPEHFSEKLRSLVSMCINPDADERPDIVFVLQFSKQMQ 265

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BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007414.1 (pep scaffold:Pmarinus_7.0:GL476981:230882:244405:1 gene:ENSPMAG00000006689.1 transcript:ENSPMAT00000007414.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 187.963 bits (476), Expect = 1.090e-56
Identity = 96/258 (37.21%), Postives = 152/258 (58.91%), Query Frame = 3

Query:  135 LSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYM 908
            + ++ +V +IG+G F +    + KA   +  +K++ I  M   K R +  KE+ +L  + HPN++    SF E   L IV++  + GDL + I    +K  L  E  I  + VQ+C  L H+H ++I+HRDIK  N+F+T  G V+LGD G+ R  +S+T  A++ +GTPYY+SPE    + YN  SD+W+LGC+LYEM  L+  F    M   +L  KI    +PP+ A+ YS ELR+ +S  + +DP +RP ++ +
Sbjct:    1 MERYTMVSQIGEGSFGKAMLVKSKADGHLYVIKEINISRM-SPKERDEARKEVCVLANMRHPNIVSYKESFEERGNLYIVMDYCEGGDLFKRINA--QKGVLFSEDQILDWLVQLCLALKHVHDRKILHRDIKSQNIFLTKAGIVQLGDFGIARVLNSTTELARTCIGTPYYLSPEICENKPYNHKSDMWALGCVLYEMCTLRHAFEAGNMK--NLVLKIIRGSFPPVSAH-YSSELRSTLSGLLRRDPRARPPVAVL 252

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BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: nek2 (NIMA-related kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-752])

HSP 1 Score: 171.014 bits (432), Expect = 3.990e-49
Identity = 99/277 (35.74%), Postives = 153/277 (55.23%), Query Frame = 3

Query:  234 KVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVE--NNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMH-----SKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYM--YGVAKEMHEKTRVDSAG----GSRTSSRQTSAGSTHSK*SIIS 1025
            KV  Y  M    +Q  + E++LL++L HPN+++     ++  N  L IV+E  + GDL+ +I   RR  + + E+ + +   Q+   L   H      + ++HRD+KPANVF+ +   VKLGD GL R     T+ A++ VGTPYYMSPE+    +YN  SDIWSLGCLLYE+ AL  PF    M    L +KIK   +  +P   YS EL  ++S+ +N     RP I  +  YG+  E+ ++ +  +A     G  T+ R+ S GS  ++  +++
Sbjct:    6 KVLDYGTMSEPEKQMLVSEVNLLRELKHPNIVRYFDRIIDRSNTTLYIVMEYCECGDLASLISRCRRDRRFLEEEFVLRVLAQLVLALRECHRRTAGGRTVLHRDLKPANVFLDARHNVKLGDFGLARILQHDTSFAKTFVGTPYYMSPEQFSRMSYNEKSDIWSLGCLLYELCALVPPFTA--MNQKQLAEKIKEGKFRRIPYR-YSDELNEIISKMLNLKDYLRPSIEQIMQYGLLAEVLDEEQARAAPEKPRGVPTTERR-SGGSPSAEEGLVA 278

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BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: NEK9 (NIMA related kinase 9 [Source:HGNC Symbol;Acc:HGNC:18591])

HSP 1 Score: 164.466 bits (415), Expect = 6.412e-45
Identity = 92/254 (36.22%), Postives = 139/254 (54.72%), Query Frame = 3

Query:  153 VKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLC-------KKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRP 893
            V+ +G+G F E         N +V  K++ +  + D K R+D   EID+L  L+H N+I     F++ N L I LE  + G L + I   ++     PEK I  YF Q+ S +  +H+ +I+HRDIK  N+F+T    +K+GD G+ +   S +  A+S VGTPYYMSPE I    YN  SDIW++GC+LYE+  L   F  D    + LC       K+++I D        YS+E++ +V +C+ +D   RP
Sbjct:   39 VRVLGRGAFGEAALYRRNEDNSLVVWKEIDLTRLSD-KERRDSQNEIDILSLLEHANIISYYNHFLDGNVLLIELEYCNGGTLYEKI--IKQHGAFFPEKDIVWYFYQLVSAVEQIHNFKILHRDIKTLNIFLTKSDLIKVGDFGISKILDSRSQMAESYVGTPYYMSPELIRGDKYNTKSDIWAMGCVLYELLTLTRTF--DATNPLKLCYEIIHGKKQVEIDDQ-------YSKEIKEVVQKCLQQDAEQRP 280

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BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: STK36 (serine/threonine kinase 36 [Source:HGNC Symbol;Acc:HGNC:17209])

HSP 1 Score: 156.762 bits (395), Expect = 5.360e-42
Identity = 90/253 (35.57%), Postives = 148/253 (58.50%), Query Frame = 3

Query:  135 LSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKM-TLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSR 890
            + K++V++ IG+G F +V++   + T ++VALK +      D + R +  +EID+++ L HPN+++ L SF  + E+ +V + A+ G+L Q+++        +PE+ + +   Q+ S L ++HS RI+HRD+KP N+ +   G VKL D G  R  S +T    S+ GTP YMSPE + E+ Y+ T+D+WS+GC+LYE+     PFY + +  LV L  K    D    P N+ S E R  +   + K+P  R
Sbjct:    1 MEKYHVLEMIGEGSFGKVYKGRKRYTGQVVALKFIPKVGRSDKELR-NLRREIDIMRGLQHPNIVQMLDSFETDKEVVVVTDYAE-GELFQILEDDGN----LPEEQVREIACQLVSALYYLHSHRILHRDMKPQNILLGKGGVVKLCDFGFARAMSINTLVLTSIKGTPLYMSPELVEEKPYDHTADLWSMGCILYELFVGTPPFYTNSIFQLVSLIIK----DPVKWPKNM-SSEFRNFLQGLLTKEPKLR 242

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BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000555.1 (pep scaffold:Pmarinus_7.0:GL477093:35206:42652:1 gene:ENSPMAG00000000500.1 transcript:ENSPMAT00000000555.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 130.183 bits (326), Expect = 1.570e-36
Identity = 63/159 (39.62%), Postives = 100/159 (62.89%), Query Frame = 3

Query:  435 QLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGD---KMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEIS 902
            Q++ +  + ++FVQ+C  + ++HS +I+HRDIK +NVF+T  G VK+GD G+ +    + + A + VGTPYY+SPE   +  Y+  SD+W+LGCLLYE+ AL+  F      ++T   L  KI   +  PL  + YSR++R LV+  +++ P  RP  S
Sbjct:    3 QIITKTNVMQWFVQVCMAVQYIHSVKILHRDIKTSNVFLTKAGTVKVGDFGISKAMEGTLDMAVTCVGTPYYLSPEMCQDLPYSSKSDVWALGCLLYELCALRPAFEASNIIRLTRRSLFYKIMRGEPDPLDES-YSRDVRALVALLLSRSPEDRPSAS 160

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BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: KIN3 (Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol [Source:SGD;Acc:S000000071])

HSP 1 Score: 149.443 bits (376), Expect = 2.985e-41
Identity = 102/328 (31.10%), Postives = 154/328 (46.95%), Query Frame = 3

Query:  102 PQNDPNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLA-SFVENNE-LNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMH---------------------SKRIMHRDIKPANVFIT-------------------------------------SYGQ--VKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIK--ICDYPPLPANIYSRELRTLVSQCINKDPNSRP 893
            PQ     P    S++ V++ IG+G F  V +     T +++  K ++ Y  M++K RQ  I E  +L QL H N+++     F E  E L + +E    GDLSQMIKH++++++ +PEK +W    Q+ + L   H                        ++HRD+KP N+F++                                      Y Q  VKLGD GL +   +S   A + VGTPYYMSPE + +Q Y+  SDIWSLGC+++EM +L  PF       ++L  KIK   CD  P     YSR L  ++   I+ +  +RP
Sbjct:   13 PQQQQGHP--PRSEYQVLEEIGRGSFGSVRKVIHIPTKKLLVRKDIK-YGHMNSKERQQLIAECSILSQLKHENIVEFYNWDFDEQKEVLYLYMEYCSRGDLSQMIKHYKQEHKYIPEKIVWGILAQLLTALYKCHYGVELPTLTTIYDRMKPPVKGKNIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEMCSLHPPFQAK--NYLELQTKIKNGKCDTVP---EYYSRGLNAIIHSMIDVNLRTRP 332

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BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: STE7 (Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318])

HSP 1 Score: 131.724 bits (330), Expect = 2.613e-34
Identity = 90/279 (32.26%), Postives = 147/279 (52.69%), Query Frame = 3

Query:  117 NSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLD-HPNVIKCLASFVE---NNELNIVLELADAGDLSQMIKHFRR---------KYQLMPEKTIWKYFVQICSGLNHMHSK-RIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMT---LVDLCKKIKICDYPPLPAN-IYSRELRTLVSQCINKDPNSRPEI 899
            N  Y  L     + +IG G    V +A     ++IVA K + + +   T   Q  ++E+ ++K +  H N+I    ++     NNE+ I++E +D G L +++  ++R         K     E TI K    + +GL+H++ + +I+HRDIKP+NV I S GQ+KL D G+ +   +S   A + VGT  YMSPERI    Y++  D+WSLG ++ E+   + P  G   T   ++DL ++I     P LP + IYS+E+   V++C  K+   R  I
Sbjct:  182 NGNYIQLQDLVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQ-LVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSI--ADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKNERERSSI 457

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BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: CDC5 (Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603])

HSP 1 Score: 129.028 bits (323), Expect = 6.372e-33
Identity = 73/249 (29.32%), Postives = 133/249 (53.41%), Query Frame = 3

Query:  162 IGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERI--HEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEIS 902
            +G+G F+  ++ +   + EI A K V    +   K R+  + EI + K + HPN+++ +  F +++ + I+LE+   G L +++K  RRK    PE  +  +  QIC  + +MHS+R++HRD+K  N+F  S   +K+GD GL    ++ +    ++ GTP Y++PE +      ++   DIWSLG +LY +   + PF    +  +   ++IK  D+        S E + L+   ++ DP  RP ++
Sbjct:   88 LGEGGFARCFQIK-DDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLK--RRKVLTEPE--VRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTI--YERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLT 329

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BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649])

HSP 1 Score: 124.02 bits (310), Expect = 3.194e-32
Identity = 63/208 (30.29%), Postives = 110/208 (52.88%), Query Frame = 3

Query:  132 SLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFY 755
            SLS F +++ +G G F  V            ALK ++ + ++  K  +    E  +L  + HP +I+   +F ++ ++ +V++  + G+L  ++    RK Q  P      Y  ++C  L ++HSK I++RD+KP N+ +   G +K+ D G  ++    T    +L GTP Y++PE +  + YN + D WS G L+YEM A  +PFY
Sbjct:   84 SLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLL----RKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVT---YTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFY 284

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BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: SPS1 (Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931])

HSP 1 Score: 124.79 bits (312), Expect = 5.338e-32
Identity = 82/248 (33.06%), Postives = 126/248 (50.81%), Query Frame = 3

Query:  162 IGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERI--HEQNYNLTSDIWSLGCLLYEMAALQSPF--YGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRP 893
            IG+G F +V++A  + T EIVA+K V + E  D    +   +EI  L +L  P +   +A+ +E+  + IV+E    G  S ++K  R     +PE+ +     ++  GL ++H +R +HRDIK AN+ +   G VKLGD G+      ST    + VGTPY+M+PE +      YN  +DIWSLG   YE+     P   Y     + +L K+      PP     +S   +  V+ C+ K P  RP
Sbjct:   24 IGRGNFGDVYKAVDRVTQEIVAIKVVNL-EHSDEDI-ELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLK--RSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHI-RSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKR-----KPPKLQGPFSDAAKDFVAGCLVKTPADRP 261

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BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO34646 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNS0])

HSP 1 Score: 418.698 bits (1075), Expect = 3.017e-147
Identity = 195/275 (70.91%), Postives = 229/275 (83.27%), Query Frame = 3

Query:  108 NDPNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMH 932
            +D  + Y  L  F + K+IG+GQFS V++A   A N+IVALKK+QI++MMD KARQDCIKEIDLLKQL+HPNVIK  ASF+ENNELNIVLELADAGDLS+MIKHF+++ +L+PE+T+WKYFVQ+ + L HMHS+R+MHRDIKPANVFIT+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPERI E  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LCKKI+ CDYPPLPA  YS++LR LVS CIN  P+ RP+I+Y+  +A EMH
Sbjct:    9 DDEYAVYNCLGNFEIEKKIGRGQFSVVYKARCTANNQIVALKKIQIFDMMDAKARQDCIKEIDLLKQLNHPNVIKYYASFIENNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLTAALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIKENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPAEHYSQQLRHLVSLCINPIPDQRPDITYINEIANEMH 283

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BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO49822 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG20])

HSP 1 Score: 193.741 bits (491), Expect = 2.426e-59
Identity = 98/256 (38.28%), Postives = 153/256 (59.77%), Query Frame = 3

Query:  135 LSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEIS 902
            + ++  VK+IG+G F +    + +   +   +K++ I  M   + R++  KE+ +L QL HPN++    SF E+  L IV++  D GDL + I   R       E  +  +FVQIC GL H+H ++I+HRDIK  N+F+T +G +K+GD G+ R   S+   A++ +GTPYY+SPE +  + YN  SDIWSLGC+LYEM  L+  F    M   +L  KI    YPP+P   YS ++R LV+Q + ++P+ RP ++
Sbjct:    1 MERYVRVKKIGEGSFGKALLVKKRNDGKHYVIKEINICRM-KPREREESRKEVKVLSQLKHPNIVSYQESFEESGNLYIVMDYCDGGDLYKKINGQRG--IAFSEDQVMDWFVQICLGLKHVHDRKILHRDIKSQNIFLTRHGIIKMGDFGIARVLHSTVELARTCIGTPYYLSPEIVENRPYNNKSDIWSLGCVLYEMLTLKHAFEAGNMK--NLVLKIIRGSYPPIPLR-YSADIRMLVAQLLKRNPHDRPSVN 250

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BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO37413 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFU9])

HSP 1 Score: 185.652 bits (470), Expect = 4.282e-56
Identity = 95/265 (35.85%), Postives = 158/265 (59.62%), Query Frame = 3

Query:  123 PYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVE--NNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKR----IMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEI 899
            P G L  +  ++RIG G +    +   K  N+++  K++   +M +T+ +Q  + E++LL++L HP++++     ++  N  + IV+E  + GDL  +IK  +R+ +   E  +WK   Q+   +   H ++    ++HRD+KPANVF+ +   VKLGD GL R  S  T+ A++ VGTPYYMSPE++++++YN  SDIWSLGCL+YE+ AL  PF    M  + L  KIK+  + P+P++ YS  L  L++  +  +   RP I
Sbjct:    2 PSGRLHDYEELERIGSGSYGICKKIRRKKDNKVLVWKELDYGQMSETE-KQMLVSEVNLLRELKHPHIVRYYDRIIDRTNTTIYIVMEFCENGDLGALIKKHKREKRYTAEDLVWKLLYQLVLAVQECHRRKDGGHVLHRDLKPANVFLDANMNVKLGDFGLARVLSHDTSFAKTFVGTPYYMSPEQVNKRSYNEKSDIWSLGCLMYELCALSPPFTA--MDQIRLEAKIKVGRFHPIPSH-YSSSLSQLINSMLQVNDEMRPSI 262

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BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO37069 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGU2])

HSP 1 Score: 180.259 bits (456), Expect = 3.910e-54
Identity = 96/253 (37.94%), Postives = 149/253 (58.89%), Query Frame = 3

Query:  138 SKFNVVKRIGKGQFSEVWRAE-VKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRP 893
            +++ VV+R+G G F  V+  E +KA  E   LK++ + E+   +   D ++E  LL +L+HPN++K + SF++     IV E  + GDL   I  +R+  +   E  I  +F+QI   + HMH  RI+HRD+K  N+F+ +   VKLGD G+ R    +++ A +  GTPYYMSPE +  + YN  SDIWSLG +LYE+  LQ  F G   +L+ +  KI   + P L ++ YS +L+   S+ ++KDP  RP
Sbjct:    4 NRYRVVRRLGSGSFGTVFLVEDLKANGERKVLKEIYVGELQPDET-VDAMREAKLLSKLNHPNIVKFMDSFMDREYFCIVTEYCEGGDLDDKISAWRKSGKKFDESLILAWFIQIVLAVQHMHEMRILHRDLKTRNIFLKN-NIVKLGDFGISRILMGTSDMATTFTGTPYYMSPEVLKHEGYNHKSDIWSLGVVLYELCNLQHAFQGQ--SLMGVMYKIVEGELPAL-SDKYSSQLQAFYSRLMDKDPKLRP 251

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BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO49690 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG02])

HSP 1 Score: 175.252 bits (443), Expect = 4.649e-52
Identity = 99/258 (38.37%), Postives = 147/258 (56.98%), Query Frame = 3

Query:  132 SLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNE-LNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEIS 902
            SL ++ + K IGKG + EV+ ++ K   +   LKKV + +    + R+    E  LL QL HPN++    SF ++   L I +   + GDL   +K   +K   + E  I ++FVQI   L +MH K I+HRD+K  N+F+T    +K+GDLG+ R   SS++ A +L+GTPYYMSPE    + YN  SD+W+LGC LYEM  L+  F    M+   L  KI     PPLP   YS +L +++   +++DP+ RP  S
Sbjct:    2 SLDRYTIGKCIGKGSYGEVFLSKHKKDKKQYVLKKVDL-QKASVRERKAAELEAKLLSQLRHPNIVSYRESFQDDTGFLYIAMNFCEGGDLYSRLK--AQKGIPLDENQIVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKSKIIKVGDLGIARVLESSSDMATTLIGTPYYMSPELFSNKPYNHKSDVWALGCCLYEMCTLRHAFNAKDMS--SLVYKILKGKTPPLPKQ-YSTDLCSIIKSMLDQDPDKRPSAS 253

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BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: nek6 (NIMA related kinase 6 [Source:NCBI gene;Acc:101173323])

HSP 1 Score: 424.476 bits (1090), Expect = 1.016e-148
Identity = 200/286 (69.93%), Postives = 236/286 (82.52%), Query Frame = 3

Query:   99 VPQNDPNSPYG-----SLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKT 941
            VP  D  +P G     S++ F V ++IG+GQFSEV+RA      + VALKKVQI+EMMD KARQDCIKEIDLLKQL+HPN+IK L SF+E+NELNIVLELADAGDLSQMIK+F++K +L+PE+TIWKYFVQ+CS L HMHS+R+MHRDIKPANVFIT+ G+VKLGDLGLGRFFSS T  A SLVGTPYYMSPERIHE  YN  SDIWSLGCLLYEMAALQSPFYGDKM L+ LC+KI+ CDYPPLP + YS +LR LVS CIN +P+ RP+I ++  +A +MH KT
Sbjct:   21 VPPEDQKNPTGCGFRCSMANFRVERKIGRGQFSEVYRAVRLLDRQSVALKKVQIFEMMDAKARQDCIKEIDLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKKRRLIPERTIWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGEVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLLSLCRKIEQCDYPPLPPDQYSDKLRELVSMCINSEPDQRPDIIFVLQIANQMHVKT 306

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BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: nek7 (NIMA related kinase 7 [Source:NCBI gene;Acc:101170580])

HSP 1 Score: 417.157 bits (1071), Expect = 6.301e-146
Identity = 196/296 (66.22%), Postives = 229/296 (77.36%), Query Frame = 3

Query:   75 KPMSNNIIVPQNDPNSP------YGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKTR 944
            +P       P   P  P      Y SL+ F + K+IGKGQFSEV+RA     N  VALKK+QI+ +MD KARQDCIKEIDLLKQL+HPNVIK  ASF+E+NELNIVLELADAGDLS+MI HF+ + +L+PEK +WKYFVQ+C  L HMHS+R+MHRDIKPANVF+T+ G VKLGDLGLGRFFSS T  A SLVGTPYYMSPER+ E  YN  SDIWSLGCLLYEMAALQSPFYGDKM L  LC KI+ CDYPPLP++ YS+ELR LV  CIN DP  RP+I+Y+Y +AK+M   T+
Sbjct:    6 QPQGQQAETPPFQPQKPLQLDMDYSSLANFQIEKKIGKGQFSEVYRARYILDNTPVALKKIQIFNLMDAKARQDCIKEIDLLKQLNHPNVIKYHASFIEDNELNIVLELADAGDLSRMINHFKNQRRLIPEKAVWKYFVQVCRALEHMHSRRVMHRDIKPANVFVTATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERLRENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCTKIQQCDYPPLPSDHYSQELRDLVDMCINPDPEKRPDITYVYDIAKKMRNMTQ 301

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BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000034147.1 (serine/threonine-protein kinase Nek5 [Source:NCBI gene;Acc:101162253])

HSP 1 Score: 188.734 bits (478), Expect = 5.273e-53
Identity = 102/259 (39.38%), Postives = 158/259 (61.00%), Query Frame = 3

Query:  135 LSKFNVVKRIGKGQFSEVW--RAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYG-QVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEIS 902
            ++ + V+ +IG+G F + +  R++    +    +K++ + + M  K R+   KE+ LL ++ HPN++  ++SF+E   L IV+E  D GDL + I + +R      E+ I   FVQIC GL H+H K+++HRDIK  N+F+T+ G + KLGD G+ R  ++S + A++ VGTPYY+SPE    + YN  +D+WSLGC+LYE+  L+ PF G   +L  L  KI    Y P+P   Y+ ELR LV+Q    +P  RP IS
Sbjct:    1 MNDYEVLWQIGEGAFGKAFLVRSKTGGGDTQCVIKQINL-QKMSAKERESSRKEVTLLSRMRHPNIVSFISSFLEKGSLFIVMEFCDGGDLLKKI-NMQRGVPFR-EEEILDLFVQICLGLKHIHDKKVLHRDIKCQNIFLTNGGMKAKLGDFGIARMLNNSMDLARTCVGTPYYLSPEICESRPYNNKTDVWSLGCVLYELCTLRHPFEGS--SLRQLLGKICRGRYAPVPTR-YTHELRLLVNQLFKVNPRDRPSIS 253

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BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000000545.2 (pep primary_assembly:ASM223467v1:4:1040495:1044496:1 gene:ENSORLG00000000439.2 transcript:ENSORLT00000000545.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 176.407 bits (446), Expect = 2.372e-52
Identity = 99/256 (38.67%), Postives = 148/256 (57.81%), Query Frame = 3

Query:  135 LSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEIS 902
            + K+  VK+IG+G F +      K       +K++ I   M TK R++  KE+ +L  + HPN+++   SF E   L IV++  + GDL + I    +K  L  E  I  +FVQIC  L H+H ++I+HRDIK  N+F+T  G V+LGD G+ R   ++   A++ +GTPYY+SPE    + YN   DIW+LGC+LYEM  L+  F    M   +L  KI    YPP+  + YS ELR+L++Q   ++P  RP +S
Sbjct:    1 MDKYENVKQIGEGSFGKAILVNSKEDGRQYVIKEIGI-SGMSTKERRESRKEVSVLANMSHPNIVQYKESF-EGGCLYIVMDYCEGGDLFKKINS--QKGVLFSEDQILDWFVQICLALKHVHGRKILHRDIKSQNIFLTKDGTVQLGDFGIARVL-NTVELARTCIGTPYYLSPEICENKPYN-NKDIWALGCVLYEMCTLKHAFEAGNMK--NLVLKIIRGSYPPVSVH-YSPELRSLLAQLFRRNPRERPSVS 247

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BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: nek2 (NIMA related kinase 2 [Source:NCBI gene;Acc:101168418])

HSP 1 Score: 170.629 bits (431), Expect = 3.020e-48
Identity = 95/261 (36.40%), Postives = 152/261 (58.24%), Query Frame = 3

Query:  144 FNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVE--NNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKR-----IMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPF--YGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEI 899
            + V+  IG G +    + + K+  +I+  K++  Y  M    +Q  + E++LL++L HPN+++     ++  N  L I++E  + GDLS +I    ++ + + E+ I +  VQ+   L   H +R     ++HRD+KPAN+F+ +   VKLGD GL R  +  T+ A++ VGTPYYMSPE+I+  +YN  SDIWSLGCLLYE+ AL  PF  Y  K    +L +KI+   +  +P   YS EL +L+S+ +N     RP +
Sbjct:    8 YEVLYTIGSGSYGRCQKIKRKSDGKILVWKELD-YGTMAECEKQMLVSEVNLLRELKHPNIVRYYDRIIDRRNTMLYIIMEYCEGGDLSCLISKCIKERKYLEEQFILRVMVQLSLALKECHRRRDGRATVLHRDLKPANIFLDANQNVKLGDFGLARILNHDTSFAKTFVGTPYYMSPEQINRMSYNEKSDIWSLGCLLYELCALSPPFTAYNQK----ELAEKIREGKFRRIPFR-YSEELNSLISRMLNLKDYLRPSV 262

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BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000055481.1 (SMESG000055481.1)

HSP 1 Score: 409.838 bits (1052), Expect = 4.717e-143
Identity = 193/284 (67.96%), Postives = 236/284 (83.10%), Query Frame = 3

Query:  105 QNDPN---SPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNE-IVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKTR 944
            QND +     + +LSKF + K+IG+GQFS V++A     N+ I+ALKKV+I+EMMD K R+DCIKEIDLLK+LDHP++IK ++SF+E+NEL IVLELADAGDLS+MIKHF ++ +L+PE+TIWKYFVQICS L +MHS+RIMHRDIKPANVFITS G+VKLGD GLGRFFS+ T++  SLVGTPYYMSPERI E  Y++ SDIWSLGC+LYEMAALQSPFYG+ +TL  LC++I+  DYPPLP  IYS ELR LV +CI  DPNSRP IS++Y VAK MHEKTR
Sbjct:    6 QNDQDYQLEAFSNLSKFKIQKKIGRGQFSTVYQACCLEINDKIIALKKVKIFEMMDAKTRRDCIKEIDLLKKLDHPHIIKLISSFIEDNELIIVLELADAGDLSRMIKHFNKQKRLIPERTIWKYFVQICSALEYMHSQRIMHRDIKPANVFITSKGEVKLGDFGLGRFFSTQTSNVHSLVGTPYYMSPERILETGYDMKSDIWSLGCVLYEMAALQSPFYGESLTLAILCQRIEESDYPPLPTRIYSSELRGLVDRCIQTDPNSRPNISHIYHVAKNMHEKTR 289

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BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000020466.1 (SMESG000020466.1)

HSP 1 Score: 196.438 bits (498), Expect = 4.556e-55
Identity = 103/260 (39.62%), Postives = 154/260 (59.23%), Query Frame = 3

Query:  129 GSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYM 908
             S+S F  + +IG+G F   W  E K   +   LK++ +Y+M + K R +  KE+ LL +++HPN++    SF E    +I++E  + GDL + IK   +   L  E  +  YF+QIC  L H+H +RI+HRDIKP N+F+T    VKLGD G+ +   S+T   ++ VGTP+Y SPE      YN  SDIWSLGC+LYE+ +L   FYG  +T+  L  +IK  +Y P+P+ ++S  LR LV     + P+ RP I+ +
Sbjct:    2 SSISDFKRLNKIGQGAFGIAWLVESKIDCKKYVLKEIGLYKMHE-KERFEARKEVSLLSKMNHPNIVTYYNSFEEVGCFHILMEYCEGGDLYRKIKT--QNGVLFKEDQVLDYFIQICLALKHIHDQRILHRDIKPQNIFLTKNNSVKLGDFGIAKAMDSTTALTKTQVGTPFYFSPEICEGCPYNNKSDIWSLGCILYELCSLNYAFYGQDITI--LAMRIKKVNYKPVPS-VFSAPLRALVDNMFRRRPDERPNINTI 255

[Close]

BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000020466.1 (SMESG000020466.1)

HSP 1 Score: 196.438 bits (498), Expect = 4.650e-55
Identity = 103/260 (39.62%), Postives = 154/260 (59.23%), Query Frame = 3

Query:  129 GSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYM 908
             S+S F  + +IG+G F   W  E K   +   LK++ +Y+M + K R +  KE+ LL +++HPN++    SF E    +I++E  + GDL + IK   +   L  E  +  YF+QIC  L H+H +RI+HRDIKP N+F+T    VKLGD G+ +   S+T   ++ VGTP+Y SPE      YN  SDIWSLGC+LYE+ +L   FYG  +T+  L  +IK  +Y P+P+ ++S  LR LV     + P+ RP I+ +
Sbjct:    2 SSISDFKRLNKIGQGAFGIAWLVESKIDCKKYVLKEIGLYKMHE-KERFEARKEVSLLSKMNHPNIVTYYNSFEEVGCFHILMEYCEGGDLYRKIKT--QNGVLFKEDQVLDYFIQICLALKHIHDQRILHRDIKPQNIFLTKNNSVKLGDFGIAKAMDSTTALTKTQVGTPFYFSPEICEGCPYNNKSDIWSLGCILYELCSLNYAFYGQDITI--LAMRIKKVNYKPVPS-VFSAPLRALVDNMFRRRPDERPNINTI 255

[Close]

BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000020466.1 (SMESG000020466.1)

HSP 1 Score: 196.438 bits (498), Expect = 4.690e-55
Identity = 103/260 (39.62%), Postives = 154/260 (59.23%), Query Frame = 3

Query:  129 GSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPEISYM 908
             S+S F  + +IG+G F   W  E K   +   LK++ +Y+M + K R +  KE+ LL +++HPN++    SF E    +I++E  + GDL + IK   +   L  E  +  YF+QIC  L H+H +RI+HRDIKP N+F+T    VKLGD G+ +   S+T   ++ VGTP+Y SPE      YN  SDIWSLGC+LYE+ +L   FYG  +T+  L  +IK  +Y P+P+ ++S  LR LV     + P+ RP I+ +
Sbjct:    2 SSISDFKRLNKIGQGAFGIAWLVESKIDCKKYVLKEIGLYKMHE-KERFEARKEVSLLSKMNHPNIVTYYNSFEEVGCFHILMEYCEGGDLYRKIKT--QNGVLFKEDQVLDYFIQICLALKHIHDQRILHRDIKPQNIFLTKNNSVKLGDFGIAKAMDSTTALTKTQVGTPFYFSPEICEGCPYNNKSDIWSLGCILYELCSLNYAFYGQDITI--LAMRIKKVNYKPVPS-VFSAPLRALVDNMFRRRPDERPNINTI 255

[Close]

BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000057044.1 (SMESG000057044.1)

HSP 1 Score: 177.948 bits (450), Expect = 7.381e-50
Identity = 93/249 (37.35%), Postives = 147/249 (59.04%), Query Frame = 3

Query:  162 IGKGQFSEVWRAE----VKATNEIVALKKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLELADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDIKPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQNYNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANIYSRELRTLVSQCINKDPNSRPE 896
            IGKG F  V++ +     +    I  LK+V + + MD    ++C +E  LL +L+H N++K   SF   N   I+ E  + GDL Q+I+  +R    + E  I ++F+Q+  GL+++H ++I+HRD+KP N+F+  Y  VK+GD G+ R  + + + A + +GTPYYMSPE +    YN  SDIWS G +LYEM AL+  F GD +  V +      C  P +P+N YS  L+ ++   + KDP++RP+
Sbjct:   21 IGKGSFGTVYKVKDFRGPEGQESIKVLKEVNV-DTMDQDQIEECTREGKLLSKLNHSNIVKFFDSFRLENNYCIITEYCEGGDLKQVIEKTKRSGSHLEELRIIRWFIQVIEGLDYIHKRKILHRDLKPNNIFL-KYDSVKIGDFGISRILNFTNDLASTFLGTPYYMSPEVLKHDGYNTASDIWSSGVILYEMCALKHAFIGDNLMRVMVTILESPC--PRIPSN-YSENLQEVLECILVKDPDNRPK 264

The following BLAST results are available for this feature:

BLAST of Protein kinase domain-containing protein vs. Ensembl Human
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
BLAST of Protein kinase domain-containing protein vs. TrEMBL
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST

BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
NEK7	5.842e-149	71.38	NIMA related kinase 7 [Source:HGNC Symbol;Acc:HGNC...	[more]
NEK7	5.842e-149	71.38	NIMA related kinase 7 [Source:HGNC Symbol;Acc:HGNC...	[more]
NEK6	4.427e-145	70.25	NIMA related kinase 6 [Source:HGNC Symbol;Acc:HGNC...	[more]
NEK6	4.427e-145	70.25	NIMA related kinase 6 [Source:HGNC Symbol;Acc:HGNC...	[more]
NEK6	4.427e-145	70.25	NIMA related kinase 6 [Source:HGNC Symbol;Acc:HGNC...	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nekl-3	2.911e-135	68.00	Serine/threonine-protein kinase nekl-3 [Source:Un...	[more]
nekl-3	2.911e-135	68.00	Serine/threonine-protein kinase nekl-3 [Source:Un...	[more]
nekl-1	4.785e-50	34.07	NEK (NEver in mitosis Kinase) Like [Source:UniPro...	[more]
nekl-1	4.840e-50	34.07	NEK (NEver in mitosis Kinase) Like [Source:UniPro...	[more]
nekl-2	4.258e-44	33.58	Serine/threonine-protein kinase nekl-2 [Source:Un...	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Nek2	1.214e-49	36.64	gene:FBgn0029970 transcript:FBtr0071142	[more]
niki	6.207e-48	35.94	gene:FBgn0045980 transcript:FBtr0084737	[more]
GckIII	3.117e-38	33.86	gene:FBgn0266465 transcript:FBtr0083399	[more]
Tao	7.952e-34	33.60	gene:FBgn0031030 transcript:FBtr0309237	[more]
Tao	9.060e-34	33.60	gene:FBgn0031030 transcript:FBtr0336692	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nek7	2.990e-151	73.43	NIMA-related kinase 7 [Source:ZFIN;Acc:ZDB-GENE-04...	[more]
nek6	5.805e-142	71.37	NIMA-related kinase 6 [Source:ZFIN;Acc:ZDB-GENE-04...	[more]
nek6	2.344e-112	59.93	NIMA-related kinase 6 [Source:ZFIN;Acc:ZDB-GENE-04...	[more]
nek1	5.020e-58	37.41	NIMA-related kinase 1 [Source:ZFIN;Acc:ZDB-GENE-04...	[more]
CABZ01040556.1	1.962e-47	35.91	NIMA related kinase 3 [Source:NCBI gene;Acc:100536...	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nek7	1.185e-148	71.74	NIMA-related kinase 7 [Source:NCBI gene;Acc:780029...	[more]
nek7	1.245e-148	71.74	NIMA-related kinase 7 [Source:NCBI gene;Acc:780029...	[more]
nek7	1.423e-148	71.74	NIMA-related kinase 7 [Source:NCBI gene;Acc:780029...	[more]
nek7	2.611e-148	71.74	NIMA-related kinase 7 [Source:NCBI gene;Acc:780029...	[more]
nek7	5.750e-148	71.74	NIMA-related kinase 7 [Source:NCBI gene;Acc:780029...	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Nek7	3.019e-149	71.74	NIMA (never in mitosis gene a)-related expressed k...	[more]
Nek7	3.019e-149	71.74	NIMA (never in mitosis gene a)-related expressed k...	[more]
Nek6	4.367e-144	69.89	NIMA (never in mitosis gene a)-related expressed k...	[more]
Nek6	4.367e-144	69.89	NIMA (never in mitosis gene a)-related expressed k...	[more]
Nek6	1.077e-142	70.94	NIMA (never in mitosis gene a)-related expressed k...	[more]

BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9ES74\|NEK7_MOUSE	2.112e-148	71.74	Serine/threonine-protein kinase Nek7 OS=Mus muscul...	[more]
sp\|Q8TDX7\|NEK7_HUMAN	2.806e-148	71.38	Serine/threonine-protein kinase Nek7 OS=Homo sapie...	[more]
sp\|D3ZBE5\|NEK7_RAT	3.062e-148	71.74	Serine/threonine-protein kinase Nek7 OS=Rattus nor...	[more]
sp\|P59895\|NEK6_RAT	6.752e-145	70.61	Serine/threonine-protein kinase Nek6 OS=Rattus nor...	[more]
sp\|A2BD05\|NEK6_PIG	1.435e-144	70.25	Serine/threonine-protein kinase Nek6 OS=Sus scrofa...	[more]

BLAST of Protein kinase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1I8GQY4	9.920e-161	76.22	Protein kinase domain-containing protein OS=Macros...	[more]
A0A267EEI4	1.610e-158	75.71	Protein kinase domain-containing protein (Fragment...	[more]
A0A267DU22	2.140e-158	75.71	Protein kinase domain-containing protein (Fragment...	[more]
A0A1S3JQM7	1.563e-157	75.00	serine/threonine-protein kinase Nek7 isoform X2 OS...	[more]
A0A1I8ICQ9	1.719e-157	72.67	Protein kinase domain-containing protein OS=Macros...	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nek7	8.956e-152	73.16	NIMA related kinase 7 [Source:NCBI gene;Acc:103046...	[more]
nek6	4.563e-142	70.41	NIMA-related kinase 6 [Source:ZFIN;Acc:ZDB-GENE-04...	[more]
nek7	8.263e-133	66.91	NIMA related kinase 7 [Source:NCBI gene;Acc:103046...	[more]
nek6	1.106e-115	58.80	NIMA-related kinase 6 [Source:ZFIN;Acc:ZDB-GENE-04...	[more]
nek6	6.510e-113	61.85	NIMA-related kinase 6 [Source:ZFIN;Acc:ZDB-GENE-04...	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000007414.1	1.090e-56	37.21	pep scaffold:Pmarinus_7.0:GL476981:230882:244405:1...	[more]
nek2	3.990e-49	35.74	NIMA-related kinase 2 [Source:ZFIN;Acc:ZDB-GENE-04...	[more]
NEK9	6.412e-45	36.22	NIMA related kinase 9 [Source:HGNC Symbol;Acc:HGNC...	[more]
STK36	5.360e-42	35.57	serine/threonine kinase 36 [Source:HGNC Symbol;Acc...	[more]
ENSPMAT00000000555.1	1.570e-36	39.62	pep scaffold:Pmarinus_7.0:GL477093:35206:42652:1 g...	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
KIN3	2.985e-41	31.10	Nonessential serine/threonine protein kinase; poss...	[more]
STE7	2.613e-34	32.26	Signal transducing MAP kinase kinase; involved in ...	[more]
CDC5	6.372e-33	29.32	Polo-like kinase; controls targeting and activatio...	[more]
TPK3	3.194e-32	30.29	cAMP-dependent protein kinase catalytic subunit; p...	[more]
SPS1	5.338e-32	33.06	Putative protein serine/threonine kinase; localize...	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO34646	3.017e-147	70.91	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49822	2.426e-59	38.28	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37413	4.282e-56	35.85	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37069	3.910e-54	37.94	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49690	4.649e-52	38.37	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nek6	1.016e-148	69.93	NIMA related kinase 6 [Source:NCBI gene;Acc:101173...	[more]
nek7	6.301e-146	66.22	NIMA related kinase 7 [Source:NCBI gene;Acc:101170...	[more]
ENSORLT00000034147.1	5.273e-53	39.38	serine/threonine-protein kinase Nek5 [Source:NCBI ...	[more]
ENSORLT00000000545.2	2.372e-52	38.67	pep primary_assembly:ASM223467v1:4:1040495:1044496...	[more]
nek2	3.020e-48	36.40	NIMA related kinase 2 [Source:NCBI gene;Acc:101168...	[more]

BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000055481.1	4.717e-143	67.96	SMESG000055481.1	[more]
SMESG000020466.1	4.556e-55	39.62	SMESG000020466.1	[more]
SMESG000020466.1	4.650e-55	39.62	SMESG000020466.1	[more]
SMESG000020466.1	4.690e-55	39.62	SMESG000020466.1	[more]
SMESG000057044.1	7.381e-50	37.35	SMESG000057044.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30011294 ID=SMED30011294|Name=Protein kinase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1216bp
CTATATAAATCTTATATGTTTGTAATTATTTTTAAAAAAATCGTTTAATT
GTTTATAAATTTGGAATTTTTTAAAAACCAATGAGCAATAACATAATTGT
GCCTCAAAACGATCCCAATAGTCCATATGGTTCGCTGAGTAAATTTAATG
TTGTAAAGAGAATAGGTAAAGGACAATTTTCTGAAGTGTGGCGGGCAGAA
GTGAAAGCCACCAATGAGATAGTTGCTTTGAAAAAAGTTCAGATTTACGA
AATGATGGATACAAAGGCAAGGCAGGATTGTATAAAGGAAATTGATTTAT
TGAAGCAATTAGATCATCCAAATGTCATAAAATGTTTGGCATCGTTTGTT
GAAAACAACGAATTGAATATTGTTTTAGAATTAGCAGATGCAGGGGACCT
GTCACAGATGATCAAGCATTTTCGAAGAAAATATCAACTAATGCCTGAGA
AAACTATTTGGAAATATTTCGTTCAAATCTGCAGTGGATTAAATCATATG
CATTCGAAAAGGATTATGCATCGAGATATTAAGCCTGCTAATGTTTTTAT
CACATCATATGGCCAAGTAAAACTTGGAGATTTGGGACTTGGAAGATTTT
TTAGCTCGTCAACTAATGATGCTCAATCTCTAGTTGGTACTCCATATTAC
ATGTCTCCGGAGAGAATTCATGAACAAAATTACAACTTGACATCTGATAT
ATGGTCCCTCGGTTGTTTATTGTATGAAATGGCAGCTTTACAATCCCCGT
TTTATGGGGATAAAATGACGCTCGTTGACTTGTGTAAGAAAATTAAAATT
TGTGACTATCCTCCGCTACCTGCAAATATTTATTCTCGTGAATTACGAAC
TTTGGTCAGTCAATGTATAAATAAGGATCCTAATTCCCGTCCAGAAATCA
GTTATATGTACGGTGTTGCTAAAGAAATGCACGAAAAAACAAGGGTGGAC
AGTGCAGGTGGCAGTCGTACGAGTAGCCGGCAAACAAGTGCCGGCAGCAC
ACATTCTAAATAATCGATAATTTCTTTATACTTTATACAACTATTTTTAA
CAATTTGATCCGTCTTAATCAATTTAGATCAATTCTGCATCCGTCCGGAT
AAAACCACTTTTACAAATACTTTTATCATTTTTCACATATCTTCGATTTA
TATTTTATATTATCATATGAAGCTGTTGTTTTTAGTAATGTTAAAATATT
TACAATATTATGTAGC

protein sequence of SMED30011294-orf-1

>SMED30011294-orf-1 ID=SMED30011294-orf-1|Name=SMED30011294-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=311bp
MSNNIIVPQNDPNSPYGSLSKFNVVKRIGKGQFSEVWRAEVKATNEIVAL
KKVQIYEMMDTKARQDCIKEIDLLKQLDHPNVIKCLASFVENNELNIVLE
LADAGDLSQMIKHFRRKYQLMPEKTIWKYFVQICSGLNHMHSKRIMHRDI
KPANVFITSYGQVKLGDLGLGRFFSSSTNDAQSLVGTPYYMSPERIHEQN
YNLTSDIWSLGCLLYEMAALQSPFYGDKMTLVDLCKKIKICDYPPLPANI
YSRELRTLVSQCINKDPNSRPEISYMYGVAKEMHEKTRVDSAGGSRTSSR
QTSAGSTHSK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000018	Category 4 cell
PLANA:0000020	protonephridia
PLANA:0000034	epidermis
PLANA:0000099	neuron
PLANA:0000418	head
PLANA:0002032	epidermal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR001245	Ser-Thr/Tyr_kinase_cat_dom
IPR000719	Prot_kinase_dom
IPR008271	Ser/Thr_kinase_AS
IPR017441	Protein_kinase_ATP_BS
IPR011009	Kinase-like_dom_sf

Vocabulary: **molecular function**
Term	Definition
GO:0004672	protein kinase activity
GO:0005524	ATP binding
GO:0000166	nucleotide binding
GO:0004674	protein serine/threonine kinase activity
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0046872	metal ion binding

Vocabulary: **biological process**
Term	Definition
GO:0006468	protein phosphorylation
GO:0016310	phosphorylation

Vocabulary: **cellular component**
Term	Definition
GO:0000922	spindle pole
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005815	microtubule organizing center
GO:0005856	cytoskeleton

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain	PRINTS	PR00109	TYRKINASE	coord: 205..227 score: 38.02 coord: 139..157 score: 27.78 coord: 251..273 score: 28.04 coord: 99..112 score: 28.33
IPR000719	Protein kinase domain	SMART	SM00220	serkin_6	coord: 22..287 e-value: 1.3E-87 score: 307.1
IPR000719	Protein kinase domain	PFAM	PF00069	Pkinase	coord: 22..274 e-value: 6.1E-66 score: 222.5
IPR000719	Protein kinase domain	PROSITE	PS50011	PROTEIN_KINASE_DOM	coord: 22..287 score: 48.061
None	No IPR available	GENE3D	G3DSA:3.30.200.20		coord: 22..102 e-value: 1.2E-85 score: 288.4
None	No IPR available	PIRSF	PIRSF000654	ILK	coord: 6..291 e-value: 9.0E-40 score: 134.3
None	No IPR available	GENE3D	G3DSA:1.10.510.10		coord: 61..270 e-value: 1.2E-85 score: 288.4
None	No IPR available	PFAM	PF12330	Haspin_kinase	coord: 28..174 e-value: 9.2E-7 score: 28.1
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 286..310
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 292..310
None	No IPR available	PANTHER	PTHR43289:SF13	SERINE/THREONINE-PROTEIN KINASE NEK6	coord: 16..287
None	No IPR available	PANTHER	PTHR43289	FAMILY NOT NAMED	coord: 16..287
None	No IPR available	CDD	cd08224	STKc_Nek6_7	coord: 21..282 e-value: 0.0 score: 522.602
IPR008271	Serine/threonine-protein kinase, active site	PROSITE	PS00108	PROTEIN_KINASE_ST	coord: 145..157
IPR017441	Protein kinase, ATP binding site	PROSITE	PS00107	PROTEIN_KINASE_ATP	coord: 28..51
IPR011009	Protein kinase-like domain superfamily	SUPERFAMILY	SSF56112	Protein kinase-like (PK-like)	coord: 20..276