Non-specific serine/threonine protein kinase

Overview
NameNon-specific serine/threonine protein kinase
Smed IDSMED30011173
Length (bp)2034
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Non-specific serine/threonine protein kinase (SMED30011173) t-SNE clustered cells

Violin plots show distribution of expression levels for Non-specific serine/threonine protein kinase (SMED30011173) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Non-specific serine/threonine protein kinase (SMED30011173) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Non-specific serine/threonine protein kinase (SMED30011173) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30011173

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30011173h1SMcG0022168 Contig667GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30011173h1SMcG0022168 dd_Smed_v4_4198_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Human
Match: SGK1 (serum/glucocorticoid regulated kinase 1 [Source:HGNC Symbol;Acc:HGNC:10810])

HSP 1 Score: 263.462 bits (672), Expect = 6.377e-81
Identity = 125/215 (58.14%), Postives = 160/215 (74.42%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKE IE   TTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K+DF EIK H FFS I+W  L+NK++ PPF P VS   D+R+ DPEF +EP+  SI  S  +     SV++  ++F+GFSY PP D
Sbjct:  171 SLNIVY-RDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTD 384
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Human
Match: SGK1 (serum/glucocorticoid regulated kinase 1 [Source:HGNC Symbol;Acc:HGNC:10810])

HSP 1 Score: 263.077 bits (671), Expect = 2.597e-80
Identity = 125/215 (58.14%), Postives = 160/215 (74.42%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKE IE   TTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K+DF EIK H FFS I+W  L+NK++ PPF P VS   D+R+ DPEF +EP+  SI  S  +     SV++  ++F+GFSY PP D
Sbjct:  215 SLNIVY-RDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTD 428
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Human
Match: SGK1 (serum/glucocorticoid regulated kinase 1 [Source:HGNC Symbol;Acc:HGNC:10810])

HSP 1 Score: 263.462 bits (672), Expect = 3.468e-80
Identity = 125/215 (58.14%), Postives = 160/215 (74.42%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKE IE   TTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K+DF EIK H FFS I+W  L+NK++ PPF P VS   D+R+ DPEF +EP+  SI  S  +     SV++  ++F+GFSY PP D
Sbjct:  229 SLNIVY-RDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTD 442
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Human
Match: SGK1 (serum/glucocorticoid regulated kinase 1 [Source:HGNC Symbol;Acc:HGNC:10810])

HSP 1 Score: 262.307 bits (669), Expect = 3.913e-80
Identity = 125/215 (58.14%), Postives = 160/215 (74.42%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKE IE   TTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K+DF EIK H FFS I+W  L+NK++ PPF P VS   D+R+ DPEF +EP+  SI  S  +     SV++  ++F+GFSY PP D
Sbjct:  205 SLNIVY-RDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTD 418
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Human
Match: SGK1 (serum/glucocorticoid regulated kinase 1 [Source:HGNC Symbol;Acc:HGNC:10810])

HSP 1 Score: 262.307 bits (669), Expect = 1.079e-79
Identity = 125/215 (58.14%), Postives = 160/215 (74.42%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKE IE   TTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K+DF EIK H FFS I+W  L+NK++ PPF P VS   D+R+ DPEF +EP+  SI  S  +     SV++  ++F+GFSY PP D
Sbjct:  243 SLNIVY-RDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPTD 456
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Celegans
Match: sgk-1 (Serine/threonine-protein kinase sgk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q2PJ68])

HSP 1 Score: 226.483 bits (576), Expect = 1.291e-66
Identity = 105/204 (51.47%), Postives = 147/204 (72.06%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYV 1850
            RDLKPEN+LLD +G+++LTDFGLCKE ++   TTSTFCGTPEYLAPE+I K+PYD++VDWW  GSV+YEM+FGLPPFYS+D ++MY +I+N PL L+ N     S+++  L++K+  +RLG++NDF +I+ HPFF  +DW  L+N+++K PF+P+V +  D  NI  EF +  I  S    Q     QL+V   D  F  F++V
Sbjct:  248 RDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAPEIILKKPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNISVPCSELITGLLQKDRSKRLGHRNDFRDIRDHPFFLPVDWDKLLNRELKAPFIPKVKNAMDTSNISKEFVEIQIDPSSLAPQ-----QLAVTHRDHDFENFTFV 446
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Celegans
Match: sgk-1 (Serine/threonine-protein kinase sgk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q2PJ68])

HSP 1 Score: 226.483 bits (576), Expect = 1.609e-66
Identity = 105/204 (51.47%), Postives = 147/204 (72.06%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYV 1850
            RDLKPEN+LLD +G+++LTDFGLCKE ++   TTSTFCGTPEYLAPE+I K+PYD++VDWW  GSV+YEM+FGLPPFYS+D ++MY +I+N PL L+ N     S+++  L++K+  +RLG++NDF +I+ HPFF  +DW  L+N+++K PF+P+V +  D  NI  EF +  I  S    Q     QL+V   D  F  F++V
Sbjct:  258 RDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAPEIILKKPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNISVPCSELITGLLQKDRSKRLGHRNDFRDIRDHPFFLPVDWDKLLNRELKAPFIPKVKNAMDTSNISKEFVEIQIDPSSLAPQ-----QLAVTHRDHDFENFTFV 456
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Celegans
Match: pkc-1 (Protein kinase C-like 1B [Source:UniProtKB/Swiss-Prot;Acc:P34885])

HSP 1 Score: 176.407 bits (446), Expect = 4.715e-47
Identity = 91/217 (41.94%), Postives = 129/217 (59.45%), Query Frame = 3 
Query: 1215 LNLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGY---KNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 1856
            L+ N    RDLK +NILLDA+GH  L DFG+CKEGI ++  TSTFCGTP+Y+APE++++  Y  SVDWW+ G ++YEM+ G PPF + +   +++ ILN  +           +IL   + KN  +RLG    +   D I+ HPFF +IDW AL ++QVKPPF P++ S  D  N D +F KE    +  +  + R          D F GFS++ P
Sbjct:  406 LHRNDVIYRDLKLDNILLDAEGHCRLADFGMCKEGINKDNLTSTFCGTPDYIAPEILQEMEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWLSKEAVNILKAFMTKNAGKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQVKPPFKPKIKSKRDANNFDSDFTKEEPVLTPSDPAVVRAIN------QDEFRGFSFINP 616
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Celegans
Match: pkc-1 (Protein kinase C-like 1B [Source:UniProtKB/Swiss-Prot;Acc:P34885])

HSP 1 Score: 176.792 bits (447), Expect = 1.102e-46
Identity = 91/217 (41.94%), Postives = 129/217 (59.45%), Query Frame = 3 
Query: 1215 LNLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGY---KNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 1856
            L+ N    RDLK +NILLDA+GH  L DFG+CKEGI ++  TSTFCGTP+Y+APE++++  Y  SVDWW+ G ++YEM+ G PPF + +   +++ ILN  +           +IL   + KN  +RLG    +   D I+ HPFF +IDW AL ++QVKPPF P++ S  D  N D +F KE    +  +  + R          D F GFS++ P
Sbjct:  493 LHRNDVIYRDLKLDNILLDAEGHCRLADFGMCKEGINKDNLTSTFCGTPDYIAPEILQEMEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWLSKEAVNILKAFMTKNAGKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQVKPPFKPKIKSKRDANNFDSDFTKEEPVLTPSDPAVVRAIN------QDEFRGFSFINP 703
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Celegans
Match: pkc-1 (Protein kinase C-like 1B [Source:UniProtKB/Swiss-Prot;Acc:P34885])

HSP 1 Score: 176.407 bits (446), Expect = 2.021e-46
Identity = 91/217 (41.94%), Postives = 129/217 (59.45%), Query Frame = 3 
Query: 1215 LNLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGY---KNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 1856
            L+ N    RDLK +NILLDA+GH  L DFG+CKEGI ++  TSTFCGTP+Y+APE++++  Y  SVDWW+ G ++YEM+ G PPF + +   +++ ILN  +           +IL   + KN  +RLG    +   D I+ HPFF +IDW AL ++QVKPPF P++ S  D  N D +F KE    +  +  + R          D F GFS++ P
Sbjct:  549 LHRNDVIYRDLKLDNILLDAEGHCRLADFGMCKEGINKDNLTSTFCGTPDYIAPEILQEMEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWLSKEAVNILKAFMTKNAGKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQVKPPFKPKIKSKRDANNFDSDFTKEEPVLTPSDPAVVRAIN------QDEFRGFSFINP 759
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Fly
Match: Akt1 (gene:FBgn0010379 transcript:FBtr0083226)

HSP 1 Score: 178.333 bits (451), Expect = 3.119e-48
Identity = 88/181 (48.62%), Postives = 116/181 (64.09%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERL-GYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPN 1778
            RDLK EN+LLD  GHI + DFGLCKE I    TT TFCGTPEYLAPEV+    Y ++VDWW  G V+YEM+ G  PFY++D   ++  IL   +    N      ++L  L+ K+PK+RL G K+D  EI+ HPFF+ I+W  LV K++ PPF PQV+S+ D R  D EF  E +  + P+
Sbjct:  307 RDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELTPPD 487
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Fly
Match: Akt1 (gene:FBgn0010379 transcript:FBtr0344470)

HSP 1 Score: 178.333 bits (451), Expect = 3.119e-48
Identity = 88/181 (48.62%), Postives = 116/181 (64.09%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERL-GYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPN 1778
            RDLK EN+LLD  GHI + DFGLCKE I    TT TFCGTPEYLAPEV+    Y ++VDWW  G V+YEM+ G  PFY++D   ++  IL   +    N      ++L  L+ K+PK+RL G K+D  EI+ HPFF+ I+W  LV K++ PPF PQV+S+ D R  D EF  E +  + P+
Sbjct:  307 RDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELTPPD 487
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Fly
Match: Akt1 (gene:FBgn0010379 transcript:FBtr0344717)

HSP 1 Score: 178.333 bits (451), Expect = 3.119e-48
Identity = 88/181 (48.62%), Postives = 116/181 (64.09%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERL-GYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPN 1778
            RDLK EN+LLD  GHI + DFGLCKE I    TT TFCGTPEYLAPEV+    Y ++VDWW  G V+YEM+ G  PFY++D   ++  IL   +    N      ++L  L+ K+PK+RL G K+D  EI+ HPFF+ I+W  LV K++ PPF PQV+S+ D R  D EF  E +  + P+
Sbjct:  307 RDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELTPPD 487
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Fly
Match: Akt1 (gene:FBgn0010379 transcript:FBtr0083227)

HSP 1 Score: 178.333 bits (451), Expect = 3.119e-48
Identity = 88/181 (48.62%), Postives = 116/181 (64.09%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERL-GYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPN 1778
            RDLK EN+LLD  GHI + DFGLCKE I    TT TFCGTPEYLAPEV+    Y ++VDWW  G V+YEM+ G  PFY++D   ++  IL   +    N      ++L  L+ K+PK+RL G K+D  EI+ HPFF+ I+W  LV K++ PPF PQV+S+ D R  D EF  E +  + P+
Sbjct:  307 RDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELTPPD 487
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Fly
Match: Pkc98E (gene:FBgn0003093 transcript:FBtr0301516)

HSP 1 Score: 178.718 bits (452), Expect = 3.447e-48
Identity = 93/230 (40.43%), Postives = 136/230 (59.13%), Query Frame = 3 
Query: 1203 FCIELNLNISFI-------RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNS----PLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKE-PISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 1856
            +  E+ L + F+       RDLK +NILLD +GH  L DFG+CKEGI     T+TFCGTP+Y+APE++K++ Y  SVDWW+ G ++YEM+ G PPF + +  +++  I++     P+ L     S++   L     KNP++RLG   D +EI+ HPFF+++DW  L  + +KPPF P++ +  D  N D EF KE P+   I N  +    Q       D F GFS+V P
Sbjct:  327 YAAEVTLALQFLHTHGVIYRDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQEYGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKGFLT----KNPEQRLGCTGDENEIRKHPFFAKLDWKELEKRNIKPPFRPKMKNPRDANNFDAEFTKEDPVLTPIGNEVVRCINQ-------DEFAGFSFVNP 545
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Zebrafish
Match: sgk3 (serum/glucocorticoid regulated kinase family member 3 [Source:ZFIN;Acc:ZDB-GENE-070424-62])

HSP 1 Score: 259.61 bits (662), Expect = 1.660e-78
Identity = 122/218 (55.96%), Postives = 157/218 (72.02%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENM 1871
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKEGI +  TT+TFCGTPEYLAPEV++K+PYD +VDWW  GSV+YEML+GLPPFYS+DTH+MY  IL+  L +R    +    IL  L+ K+   RLGY++DF+E+K H FFS I+W  L  K++ PPF P V S  DI N DPEF +E +  S+  S        SV + DD+F+GFSY PP +++ 
Sbjct:  269 SLNIVY-RDLKPENILLDSQGHIVLTDFGLCKEGISQADTTTTFCGTPEYLAPEVLRKQPYDNTVDWWCLGSVLYEMLYGLPPFYSRDTHEMYDNILHKELVMRPGASTAAWSILQTLLEKDHTRRLGYRDDFNEVKEHEFFSSINWYDLEQKKLSPPFNPSVESQYDISNFDPEFTEETVPNSVCFSSGPSIVNASVMEADDAFLGFSYAPPSEDSF 485
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Zebrafish
Match: sgk1 (serum/glucocorticoid regulated kinase 1 [Source:NCBI gene;Acc:324140])

HSP 1 Score: 254.988 bits (650), Expect = 2.580e-77
Identity = 122/215 (56.74%), Postives = 157/215 (73.02%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHIILTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG+ +DF EIK H FFS I+W  L  K++ PPF P V+   D+R+ DPEF  EP+  SI  S  +     S+ +  ++F+GFSY P +D
Sbjct:  217 SLNIVY-RDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNISNAARHLLEGLLQKDRTKRLGFTDDFTEIKNHMFFSPINWDDLNAKKLTPPFNPNVTGPNDLRHFDPEFTDEPVPNSIGCSPDSALVTSSITEATEAFLGFSYAPAMD 430
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Zebrafish
Match: sgk1 (serum/glucocorticoid regulated kinase 1 [Source:NCBI gene;Acc:324140])

HSP 1 Score: 254.988 bits (650), Expect = 2.580e-77
Identity = 122/215 (56.74%), Postives = 157/215 (73.02%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHIILTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG+ +DF EIK H FFS I+W  L  K++ PPF P V+   D+R+ DPEF  EP+  SI  S  +     S+ +  ++F+GFSY P +D
Sbjct:  217 SLNIVY-RDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNISNAARHLLEGLLQKDRTKRLGFTDDFTEIKNHMFFSPINWDDLNAKKLTPPFNPNVTGPNDLRHFDPEFTDEPVPNSIGCSPDSALVTSSITEATEAFLGFSYAPAMD 430
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Zebrafish
Match: si:ch211-195b13.1 (si:ch211-195b13.1 [Source:ZFIN;Acc:ZDB-GENE-030131-7626])

HSP 1 Score: 249.98 bits (637), Expect = 9.073e-76
Identity = 117/208 (56.25%), Postives = 154/208 (74.04%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            RDLKPENILLD+QGHI+LTDFGLCKEG++  GTT+TFCGTPEYLAPEV++K+ YDR+VDWW  GSV++EML+GLPPFYS++T +MY  IL+ PL L+ N  +   D+L  L+ K+  +RLG K+DF E+K H FFS I+W  L+ K++ PPF+P V+   D+R+ DPEF   P+S S+ N+  N     SV +   +F GFSY PP D
Sbjct:  202 RDLKPENILLDSQGHIVLTDFGLCKEGLDPNGTTTTFCGTPEYLAPEVLQKQAYDRTVDWWCLGSVLFEMLYGLPPFYSRNTAEMYNNILHKPLVLKPNVSNAGRDLLEGLLHKDRTKRLGSKDDFLELKFHSFFSPINWDDLMAKRIVPPFIPTVTGPTDLRHFDPEFTHLPVSTSLCNTD-NLHVTSSVREAAGAFPGFSYGPPSD 408
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Zebrafish
Match: si:ch211-195b13.1 (si:ch211-195b13.1 [Source:ZFIN;Acc:ZDB-GENE-030131-7626])

HSP 1 Score: 250.366 bits (638), Expect = 9.377e-76
Identity = 117/208 (56.25%), Postives = 154/208 (74.04%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            RDLKPENILLD+QGHI+LTDFGLCKEG++  GTT+TFCGTPEYLAPEV++K+ YDR+VDWW  GSV++EML+GLPPFYS++T +MY  IL+ PL L+ N  +   D+L  L+ K+  +RLG K+DF E+K H FFS I+W  L+ K++ PPF+P V+   D+R+ DPEF   P+S S+ N+  N     SV +   +F GFSY PP D
Sbjct:  214 RDLKPENILLDSQGHIVLTDFGLCKEGLDPNGTTTTFCGTPEYLAPEVLQKQAYDRTVDWWCLGSVLFEMLYGLPPFYSRNTAEMYNNILHKPLVLKPNVSNAGRDLLEGLLHKDRTKRLGSKDDFLELKFHSFFSPINWDDLMAKRIVPPFIPTVTGPTDLRHFDPEFTHLPVSTSLCNTD-NLHVTSSVREAAGAFPGFSYGPPSD 420
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Xenopus
Match: sgk1 (serum/glucocorticoid regulated kinase 1 [Source:NCBI gene;Acc:594981])

HSP 1 Score: 263.462 bits (672), Expect = 6.252e-81
Identity = 124/215 (57.67%), Postives = 164/215 (76.28%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHIILTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +   ++L  L++K+  +R+G KNDF EIK H FFS I+W  L+NK++ PPF P VS  +D+++ DPEF +EP+  SI  S  +     S+++  ++F+GFSY PP++
Sbjct:  174 SLNIVY-RDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARNLLEGLLQKDRTKRIGAKNDFMEIKNHMFFSPINWDDLINKKITPPFNPNVSGPSDLQHFDPEFTEEPVPNSIGQSPDSILITASIKEAAEAFMGFSYAPPME 387
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Xenopus
Match: sgk1 (serum/glucocorticoid regulated kinase 1 [Source:NCBI gene;Acc:594981])

HSP 1 Score: 263.462 bits (672), Expect = 8.649e-81
Identity = 124/215 (57.67%), Postives = 164/215 (76.28%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHIILTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +   ++L  L++K+  +R+G KNDF EIK H FFS I+W  L+NK++ PPF P VS  +D+++ DPEF +EP+  SI  S  +     S+++  ++F+GFSY PP++
Sbjct:  189 SLNIVY-RDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARNLLEGLLQKDRTKRIGAKNDFMEIKNHMFFSPINWDDLINKKITPPFNPNVSGPSDLQHFDPEFTEEPVPNSIGQSPDSILITASIKEAAEAFMGFSYAPPME 402
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Xenopus
Match: sgk1 (serum/glucocorticoid regulated kinase 1 [Source:NCBI gene;Acc:594981])

HSP 1 Score: 261.922 bits (668), Expect = 1.199e-80
Identity = 124/215 (57.67%), Postives = 164/215 (76.28%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHIILTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +   ++L  L++K+  +R+G KNDF EIK H FFS I+W  L+NK++ PPF P VS  +D+++ DPEF +EP+  SI  S  +     S+++  ++F+GFSY PP++
Sbjct:  153 SLNIVY-RDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARNLLEGLLQKDRTKRIGAKNDFMEIKNHMFFSPINWDDLINKKITPPFNPNVSGPSDLQHFDPEFTEEPVPNSIGQSPDSILITASIKEAAEAFMGFSYAPPME 366
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Xenopus
Match: sgk1 (serum/glucocorticoid regulated kinase 1 [Source:NCBI gene;Acc:594981])

HSP 1 Score: 263.462 bits (672), Expect = 1.830e-80
Identity = 124/215 (57.67%), Postives = 164/215 (76.28%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHIILTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +   ++L  L++K+  +R+G KNDF EIK H FFS I+W  L+NK++ PPF P VS  +D+++ DPEF +EP+  SI  S  +     S+++  ++F+GFSY PP++
Sbjct:  218 SLNIVY-RDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARNLLEGLLQKDRTKRIGAKNDFMEIKNHMFFSPINWDDLINKKITPPFNPNVSGPSDLQHFDPEFTEEPVPNSIGQSPDSILITASIKEAAEAFMGFSYAPPME 431
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Xenopus
Match: sgk1 (serum/glucocorticoid regulated kinase 1 [Source:NCBI gene;Acc:594981])

HSP 1 Score: 261.536 bits (667), Expect = 2.182e-80
Identity = 124/215 (57.67%), Postives = 164/215 (76.28%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHIILTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +   ++L  L++K+  +R+G KNDF EIK H FFS I+W  L+NK++ PPF P VS  +D+++ DPEF +EP+  SI  S  +     S+++  ++F+GFSY PP++
Sbjct:  161 SLNIVY-RDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARNLLEGLLQKDRTKRIGAKNDFMEIKNHMFFSPINWDDLINKKITPPFNPNVSGPSDLQHFDPEFTEEPVPNSIGQSPDSILITASIKEAAEAFMGFSYAPPME 374
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Mouse
Match: Sgk1 (serum/glucocorticoid regulated kinase 1 [Source:MGI Symbol;Acc:MGI:1340062])

HSP 1 Score: 267.314 bits (682), Expect = 2.242e-82
Identity = 126/215 (58.60%), Postives = 163/215 (75.81%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K+DF EIK H FFS I+W  L+NK++ PPF P VS  +D+R+ DPEF +EP+  SI  S  +     SV++  ++F+GFSY PP+D
Sbjct:  188 SLNIVY-RDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIGRSPDSILVTASVKEAAEAFLGFSYAPPVD 401
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Mouse
Match: Sgk1 (serum/glucocorticoid regulated kinase 1 [Source:MGI Symbol;Acc:MGI:1340062])

HSP 1 Score: 267.7 bits (683), Expect = 2.895e-82
Identity = 126/215 (58.60%), Postives = 163/215 (75.81%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K+DF EIK H FFS I+W  L+NK++ PPF P VS  +D+R+ DPEF +EP+  SI  S  +     SV++  ++F+GFSY PP+D
Sbjct:  215 SLNIVY-RDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIGRSPDSILVTASVKEAAEAFLGFSYAPPVD 428
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Mouse
Match: Sgk1 (serum/glucocorticoid regulated kinase 1 [Source:MGI Symbol;Acc:MGI:1340062])

HSP 1 Score: 268.085 bits (684), Expect = 3.491e-82
Identity = 126/215 (58.60%), Postives = 163/215 (75.81%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K+DF EIK H FFS I+W  L+NK++ PPF P VS  +D+R+ DPEF +EP+  SI  S  +     SV++  ++F+GFSY PP+D
Sbjct:  229 SLNIVY-RDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIGRSPDSILVTASVKEAAEAFLGFSYAPPVD 442
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Mouse
Match: Sgk1 (serum/glucocorticoid regulated kinase 1 [Source:MGI Symbol;Acc:MGI:1340062])

HSP 1 Score: 266.929 bits (681), Expect = 3.798e-82
Identity = 126/215 (58.60%), Postives = 163/215 (75.81%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K+DF EIK H FFS I+W  L+NK++ PPF P VS  +D+R+ DPEF +EP+  SI  S  +     SV++  ++F+GFSY PP+D
Sbjct:  201 SLNIVY-RDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIGRSPDSILVTASVKEAAEAFLGFSYAPPVD 414
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Mouse
Match: Sgk1 (serum/glucocorticoid regulated kinase 1 [Source:MGI Symbol;Acc:MGI:1340062])

HSP 1 Score: 265.774 bits (678), Expect = 1.955e-80
Identity = 126/215 (58.60%), Postives = 163/215 (75.81%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K+DF EIK H FFS I+W  L+NK++ PPF P VS  +D+R+ DPEF +EP+  SI  S  +     SV++  ++F+GFSY PP+D
Sbjct:  308 SLNIVY-RDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIGRSPDSILVTASVKEAAEAFLGFSYAPPVD 521
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. UniProt/SwissProt
Match: sp|Q9WVC6|SGK1_MOUSE (Serine/threonine-protein kinase Sgk1 OS=Mus musculus OX=10090 GN=Sgk1 PE=1 SV=1)

HSP 1 Score: 267.7 bits (683), Expect = 2.025e-81
Identity = 126/215 (58.60%), Postives = 163/215 (75.81%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K+DF EIK H FFS I+W  L+NK++ PPF P VS  +D+R+ DPEF +EP+  SI  S  +     SV++  ++F+GFSY PP+D
Sbjct:  215 SLNIVY-RDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIGRSPDSILVTASVKEAAEAFLGFSYAPPVD 428
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. UniProt/SwissProt
Match: sp|A7MB74|SGK1_BOVIN (Serine/threonine-protein kinase Sgk1 OS=Bos taurus OX=9913 GN=SGK1 PE=2 SV=1)

HSP 1 Score: 267.7 bits (683), Expect = 2.372e-81
Identity = 126/215 (58.60%), Postives = 163/215 (75.81%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K+DF EIK H FFS I+W  L+NK++ PPF P VS  +D+R+ DPEF +EP+  SI  S  +     SV++  ++F+GFSY PP+D
Sbjct:  215 SLNIVY-RDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHVLEGLLQKDRTKRLGAKDDFMEIKNHVFFSLINWEDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPNSIGRSPDSLLLTASVKEAAEAFLGFSYAPPMD 428
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. UniProt/SwissProt
Match: sp|Q6U1I9|SGK1_CHICK (Serine/threonine-protein kinase Sgk1 OS=Gallus gallus OX=9031 GN=SGK1 PE=2 SV=1)

HSP 1 Score: 266.159 bits (679), Expect = 9.610e-81
Identity = 126/215 (58.60%), Postives = 161/215 (74.88%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K DF EIK H FFS I+W  L+NK++ PPF P VS  +D+R+ DPEF  EP+  SI  S  +     SV++  ++F+GFSY PP+D
Sbjct:  216 SLNIVY-RDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKEDFTEIKNHIFFSPINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTDEPVPNSIGQSPDSILITASVKEAAEAFLGFSYAPPVD 429
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. UniProt/SwissProt
Match: sp|Q9XT18|SGK1_RABIT (Serine/threonine-protein kinase Sgk1 OS=Oryctolagus cuniculus OX=9986 GN=SGK1 PE=2 SV=1)

HSP 1 Score: 265.388 bits (677), Expect = 1.517e-80
Identity = 125/215 (58.14%), Postives = 163/215 (75.81%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K+DF EI+ H FFS I+W  L+NK++ PPF P VS  +D+R+ DPEF +EP+  SI  S  +     SV++  ++F+GFSY PP+D
Sbjct:  215 SLNIVY-RDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIRNHVFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIGRSPDSILITASVKEAAEAFLGFSYAPPMD 428
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. UniProt/SwissProt
Match: sp|Q06226|SGK1_RAT (Serine/threonine-protein kinase Sgk1 OS=Rattus norvegicus OX=10116 GN=Sgk1 PE=1 SV=1)

HSP 1 Score: 264.233 bits (674), Expect = 4.599e-80
Identity = 126/215 (58.60%), Postives = 163/215 (75.81%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K+DF EIK H FFS I+W  L+NK++ PPF P VS  +D+R+ DPEF +EP+  SI  S  +     SV++  ++F+GFSY PP+D
Sbjct:  215 SLNIVY-RDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLK-NITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIGRSPDSILVTASVKEAAEAFLGFSYAPPMD 427
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. TrEMBL
Match: W5PZ92 (Non-specific serine/threonine protein kinase OS=Ovis aries OX=9940 GN=SGK1 PE=4 SV=1)

HSP 1 Score: 271.552 bits (693), Expect = 2.472e-80
Identity = 126/215 (58.60%), Postives = 163/215 (75.81%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K+DF EIK H FFS I+W  L+NK++ PPF P VS  +D+R+ DPEF +EP+  SI  S  +     SV++  ++F+GFSY PP+D
Sbjct:  215 SLNIVYSRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHVLEGLLQKDRTKRLGAKDDFMEIKNHVFFSLINWEDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPNSIGRSPDSLLLTASVKEAAEAFLGFSYAPPMD 429
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. TrEMBL
Match: H3CXL8 (Non-specific serine/threonine protein kinase OS=Tetraodon nigroviridis OX=99883 PE=3 SV=1)

HSP 1 Score: 272.322 bits (695), Expect = 6.325e-80
Identity = 129/218 (59.17%), Postives = 163/218 (74.77%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENM 1871
            +LNI + RDLKPENILLD +GHI+LTDFGLCKEGI +  TTSTFCGTPEYLAPEV++K+PYD +VDWW  GSV+YEMLFGLPPFYS+DTH+MY  IL+ PL +R    S    +L  L+ K+   RLG +NDFDEIKVH FFS I+W  LV K++ PPF P+V+S +DI N DPEF +E +  S+  SQ +     SV + DD+F+GFSY PP +++ 
Sbjct:  275 SLNIVY-RDLKPENILLDHEGHIVLTDFGLCKEGISQSDTTSTFCGTPEYLAPEVLRKQPYDNTVDWWCLGSVLYEMLFGLPPFYSRDTHEMYDNILHKPLAMRAGASSTAWSLLQGLLEKDGTHRLGSRNDFDEIKVHNFFSSINWDDLVQKKIPPPFTPKVNSFSDISNFDPEFTEEMVPKSVCWSQDHSIVNASVMEADDAFLGFSYAPPSEDSF 491
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. TrEMBL
Match: A0A4W4FCW0 (Non-specific serine/threonine protein kinase OS=Electrophorus electricus OX=8005 GN=sgk3 PE=4 SV=1)

HSP 1 Score: 266.159 bits (679), Expect = 7.134e-80
Identity = 125/218 (57.34%), Postives = 159/218 (72.94%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENM 1871
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKEGI +  TT+TFCGTPEYLAPEV++K+PYD +VDWW  GSV+YEML+GLPPFYS+DTH+MY  IL+  L LR    +    IL  L+ K+  +RLG+K DF+E+K H FFS I+W  L+ K++ PPF P V S  DI N DPEF  E +S S+  S  +     SV + DD+F+GFSY PP D++ 
Sbjct:   93 SLNIVY-RDLKPENILLDSQGHIVLTDFGLCKEGISQADTTTTFCGTPEYLAPEVLRKQPYDNTVDWWCLGSVLYEMLYGLPPFYSRDTHEMYDNILHKELTLRPGASTSAWSILQALLEKDHTKRLGFKEDFNEVKRHSFFSSINWDDLMAKKITPPFNPSVDSQYDISNFDPEFTDETVSNSVCISTEHSVVNASVMEADDAFLGFSYAPPSDDSF 309
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. TrEMBL
Match: G1MC21 (Non-specific serine/threonine protein kinase OS=Ailuropoda melanoleuca OX=9646 GN=SGK1 PE=4 SV=1)

HSP 1 Score: 270.396 bits (690), Expect = 7.254e-80
Identity = 126/215 (58.60%), Postives = 163/215 (75.81%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHI+LTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +    +L  L++K+  +RLG K+DF EIK H FFS I+W  L+NK++ PPF P VS  +D+R+ DPEF +EP+  SI  S  +     SV++  ++F+GFSY PP+D
Sbjct:  215 SLNIVYSRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKNHVFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPNSIGRSPDSILLTASVKEAAEAFLGFSYAPPMD 429
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. TrEMBL
Match: Q4SFC2 (Non-specific serine/threonine protein kinase OS=Tetraodon nigroviridis OX=99883 GN=GSTENG00019161001 PE=4 SV=1)

HSP 1 Score: 272.322 bits (695), Expect = 1.364e-79
Identity = 129/218 (59.17%), Postives = 163/218 (74.77%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENM 1871
            +LNI + RDLKPENILLD +GHI+LTDFGLCKEGI +  TTSTFCGTPEYLAPEV++K+PYD +VDWW  GSV+YEMLFGLPPFYS+DTH+MY  IL+ PL +R    S    +L  L+ K+   RLG +NDFDEIKVH FFS I+W  LV K++ PPF P+V+S +DI N DPEF +E +  S+  SQ +     SV + DD+F+GFSY PP +++ 
Sbjct:  301 SLNIVY-RDLKPENILLDHEGHIVLTDFGLCKEGISQSDTTSTFCGTPEYLAPEVLRKQPYDNTVDWWCLGSVLYEMLFGLPPFYSRDTHEMYDNILHKPLAMRAGASSTAWSLLQGLLEKDGTHRLGSRNDFDEIKVHNFFSSINWDDLVQKKIPPPFTPKVNSFSDISNFDPEFTEEMVPKSVCWSQDHSIVNASVMEADDAFLGFSYAPPSEDSF 517
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Cavefish
Match: sgk3 (serum/glucocorticoid regulated kinase family member 3 [Source:NCBI gene;Acc:103040639])

HSP 1 Score: 264.233 bits (674), Expect = 2.857e-80
Identity = 124/218 (56.88%), Postives = 159/218 (72.94%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENM 1871
            +LNI + RDLKPENILLD QGHI+LTDFGLCKEGI +  TT+TFCGTPEYLAPEV++K+PYD +VDWW  GSV+YEML+GLPPFYS+DTH+MY+ IL+  LP+R    +    IL  L+ K+   RLGY++DF+E+K H FFS I+W  L  K++ PPF P V S  DI N DPEF +E +  S+  S  +     SV + DD+F+GFSY PP D++ 
Sbjct:  268 SLNIVY-RDLKPENILLDFQGHIVLTDFGLCKEGISQADTTTTFCGTPEYLAPEVLRKQPYDNTVDWWCLGSVLYEMLYGLPPFYSRDTHEMYENILHKELPMRPGASTTAWSILQGLLEKDNTRRLGYRDDFNEVKSHDFFSSINWDDLEQKKIPPPFNPSVDSQYDISNFDPEFTEETVPNSVCISTEHSIVNASVMEADDAFLGFSYAPPSDDSF 484
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Cavefish
Match: sgk3 (serum/glucocorticoid regulated kinase family member 3 [Source:NCBI gene;Acc:103040639])

HSP 1 Score: 257.299 bits (656), Expect = 1.582e-78
Identity = 123/218 (56.42%), Postives = 158/218 (72.48%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENM 1871
            +LNI + RDLKPENILLD QGHI+LTDFGLCKEGI +  TT+TFCGTPEYLAPEV++K+PYD +VDWW  GSV+YEML+GLPPFYS+DTH+MY+ IL+  LP+R    +    IL  L+ K+   RLGY++DF+E+K H FFS I+W  L  K++ PPF P V    DI N DPEF +E +  S+  S  +     SV + DD+F+GFSY PP D++ 
Sbjct:  203 SLNIVY-RDLKPENILLDFQGHIVLTDFGLCKEGISQADTTTTFCGTPEYLAPEVLRKQPYDNTVDWWCLGSVLYEMLYGLPPFYSRDTHEMYENILHKELPMRPGASTTAWSILQGLLEKDNTRRLGYRDDFNEVKSHDFFSSINWDDLEQKKIPPPFNPSV---YDISNFDPEFTEETVPNSVCISTEHSIVNASVMEADDAFLGFSYAPPSDDSF 416
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Cavefish
Match: si:ch211-195b13.1 (serine/threonine-protein kinase Sgk1-like [Source:NCBI gene;Acc:103036792])

HSP 1 Score: 250.366 bits (638), Expect = 5.033e-76
Identity = 117/208 (56.25%), Postives = 154/208 (74.04%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            RDLKPENILLD+QGHI+LTDFGLCKEG+E  GTT+TFCGTPEYLAPEV++K+ YDR+VDWW  GSV+YEML+GLPPFYS++T +MY  IL+  L L+ N  +   ++L  L++K+  +RLG K+DF E+K H FFS I+W  L+ +++ PPFVP V+   D+R+ DPEF   P+S S+ N+  N     SV +   +F GFSY PP D
Sbjct:  192 RDLKPENILLDSQGHIVLTDFGLCKEGLEPNGTTTTFCGTPEYLAPEVLQKQAYDRTVDWWCLGSVLYEMLYGLPPFYSRNTAEMYNNILHKSLVLKPNVSNAGRELLEGLLQKDRTKRLGVKDDFLELKYHTFFSPINWDDLMARKISPPFVPSVTGPTDLRHFDPEFTHLPVSTSLFNTD-NLHVTSSVREAAGAFPGFSYGPPAD 398
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Cavefish
Match: si:ch211-195b13.1 (serine/threonine-protein kinase Sgk1-like [Source:NCBI gene;Acc:103036792])

HSP 1 Score: 249.98 bits (637), Expect = 8.044e-76
Identity = 117/208 (56.25%), Postives = 154/208 (74.04%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            RDLKPENILLD+QGHI+LTDFGLCKEG+E  GTT+TFCGTPEYLAPEV++K+ YDR+VDWW  GSV+YEML+GLPPFYS++T +MY  IL+  L L+ N  +   ++L  L++K+  +RLG K+DF E+K H FFS I+W  L+ +++ PPFVP V+   D+R+ DPEF   P+S S+ N+  N     SV +   +F GFSY PP D
Sbjct:  200 RDLKPENILLDSQGHIVLTDFGLCKEGLEPNGTTTTFCGTPEYLAPEVLQKQAYDRTVDWWCLGSVLYEMLYGLPPFYSRNTAEMYNNILHKSLVLKPNVSNAGRELLEGLLQKDRTKRLGVKDDFLELKYHTFFSPINWDDLMARKISPPFVPSVTGPTDLRHFDPEFTHLPVSTSLFNTD-NLHVTSSVREAAGAFPGFSYGPPAD 406
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Cavefish
Match: si:ch211-195b13.1 (serine/threonine-protein kinase Sgk1-like [Source:NCBI gene;Acc:103036792])

HSP 1 Score: 250.366 bits (638), Expect = 9.396e-76
Identity = 117/208 (56.25%), Postives = 154/208 (74.04%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            RDLKPENILLD+QGHI+LTDFGLCKEG+E  GTT+TFCGTPEYLAPEV++K+ YDR+VDWW  GSV+YEML+GLPPFYS++T +MY  IL+  L L+ N  +   ++L  L++K+  +RLG K+DF E+K H FFS I+W  L+ +++ PPFVP V+   D+R+ DPEF   P+S S+ N+  N     SV +   +F GFSY PP D
Sbjct:  216 RDLKPENILLDSQGHIVLTDFGLCKEGLEPNGTTTTFCGTPEYLAPEVLQKQAYDRTVDWWCLGSVLYEMLYGLPPFYSRNTAEMYNNILHKSLVLKPNVSNAGRELLEGLLQKDRTKRLGVKDDFLELKYHTFFSPINWDDLMARKISPPFVPSVTGPTDLRHFDPEFTHLPVSTSLFNTD-NLHVTSSVREAAGAFPGFSYGPPAD 422
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006766.1 (pep scaffold:Pmarinus_7.0:GL478342:9725:27922:-1 gene:ENSPMAG00000006086.1 transcript:ENSPMAT00000006766.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 244.973 bits (624), Expect = 1.760e-74
Identity = 117/216 (54.17%), Postives = 151/216 (69.91%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDE 1865
            +LNI + RDLKPENILLD QGHI+LTDFGLCKEGI+   TT TFCGTPEYLAPEV+KK PYDR+VDWW  G V+YEML+GLPPFYS++  QMY+ IL+ PL LR    +    +L  L+ K+P +RLG  +D  EIK H FFS I+W  L  K++  P+ P VS   D+ N DP F  EP+S S+  S        +V++  D+FVGF+Y+P +++
Sbjct:  209 SLNIVY-RDLKPENILLDYQGHIVLTDFGLCKEGIDPHSTTCTFCGTPEYLAPEVLKKHPYDRTVDWWCLGCVLYEMLYGLPPFYSKNLKQMYESILHQPLQLRPCTTNAAISVLEGLLHKDPHQRLGATSDILEIKNHVFFSTINWNDLDAKRIPSPYNPGVSGPCDLHNFDPAFTAEPLSMSMAQSSDTSSVCANVDEAADAFVGFTYMPGLED 423
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008480.1 (pep scaffold:Pmarinus_7.0:GL482122:191709:206473:1 gene:ENSPMAG00000007654.1 transcript:ENSPMAT00000008480.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 172.555 bits (436), Expect = 3.791e-47
Identity = 83/181 (45.86%), Postives = 115/181 (63.54%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYK-NDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPN 1778
            RDLK EN++LD  GHI + DFGLCKEGI    T  TFCGTPEYLAPEV++   Y R+VDWW  G V+YEM+ G  PFY+QD  ++++ IL   +       +    +L  L++K+PK+RLG   +D  EI  H FF+ I W  + ++++ PPF PQV+S  D R  D EF  + I+ + P+
Sbjct:  273 RDLKLENLMLDKDGHIKIADFGLCKEGITDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIRFPRTLSNDARALLSGLLKKDPKQRLGGGVDDAKEIMRHSFFAGIIWQDVYDRKMTPPFKPQVASETDTRYFDEEFTAQTITITPPD 453
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Sea Lamprey
Match: sgk1 (serum/glucocorticoid regulated kinase 1 [Source:NCBI gene;Acc:324140])

HSP 1 Score: 156.377 bits (394), Expect = 1.251e-42
Identity = 93/220 (42.27%), Postives = 122/220 (55.45%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPE---YLAPEVIKKEPYDRSVDW-----WSFGSV------IYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 1856
            RDLKPENILLD +GHIILTDFGLCKEGI+   TTSTFCGTPE       + I+ +   R+  W     W  G V      + E+ F   P +SQ                + N  +   D+L  L+ K+  +RLG   DF EIK H FFS I+W  L++K++ PPF P V+  +D+R+ DPEF  EP+ GS+  S        S ++  D+F GFSY PP
Sbjct:  132 RDLKPENILLDFEGHIILTDFGLCKEGIQPNDTTSTFCGTPEESDLTNRKEIRSQRSSRTRGWDLRCAWRAGQVTTHRPSVSEVSF--VPSFSQSRR------------FKPNISNSARDLLEGLLHKDRTQRLGASGDFTEIKGHVFFSPINWEDLLSKKIVPPFNPNVNGPSDLRHFDPEFISEPVPGSVCRSPGEFAVSASFQEARDAFAGFSYAPP 337
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001814.1 (pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gene:ENSPMAG00000001637.1 transcript:ENSPMAT00000001814.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 151.754 bits (382), Expect = 1.461e-41
Identity = 73/175 (41.71%), Postives = 113/175 (64.57%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLG-YKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPI 1760
            RDLKPEN+L+D QG+I +TDFG  K     +G T T CGTPEYLAPE+I  + Y+++VDWW+ G +IYEM  G PPF++    Q+Y++I++  +    +  S + D+L  L++ +  +R G  KN  ++IK H +FS  DW+A+  ++V+ PF+P+     D  N D ++ +E I
Sbjct:  103 RDLKPENLLIDQQGYIQVTDFGFAKR---VKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYQRKVEAPFIPKCKGPGDASNFD-DYEEEEI 273
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Sea Lamprey
Match: PRKCD (protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399])

HSP 1 Score: 142.895 bits (359), Expect = 9.734e-39
Identity = 71/158 (44.94%), Postives = 98/158 (62.03%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSS 1712
            RDLK +NILLD  GH+ + DFG+CKE I  +    TFCGTP+Y+APE++  + Y+ SVDWWSFG ++YEML G  PF   D  ++++ I  S             DIL  L+ + P +RLG      EI+ HPFF  I+W AL  ++++PPF P+V S
Sbjct:  112 RDLKLDNILLDKDGHVKIADFGMCKENIVGDVRAGTFCGTPDYIAPEIVIGQKYNCSVDWWSFGVLLYEMLIGQSPFRGDDEEELFESIRTSVPYYPRWITKDSRDILPLLLEREPMKRLGVTG---EIRQHPFFRTINWEALEKRELEPPFKPRVVS 266
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Yeast
Match: YPK1 (S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609])

HSP 1 Score: 194.126 bits (492), Expect = 1.150e-53
Identity = 97/204 (47.55%), Postives = 129/204 (63.24%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYV 1850
            RDLKPENILLD QGHI L DFGLCK  ++ +  T TFCGTPEYLAPE++    Y ++VDWW+ G ++YEML GLPP+Y +D  +MY++IL  PL           D+L+ L+ ++P  RLGY N  DEI+ HPFFSQ+ W  L+ K   PP+ P VS++ D  N D EF +E    S+ +  L+       E V   F G++YV
Sbjct:  469 RDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLGY-NGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKPIDSVVDEYLS-------ESVQKQFGGWTYV 664
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Yeast
Match: YPK2 (Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710])

HSP 1 Score: 181.8 bits (460), Expect = 2.220e-49
Identity = 94/213 (44.13%), Postives = 126/213 (59.15%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENMAN 1877
            RDLKPENILLD QGHI L DFGLCK  ++    T TFCGTPEYLAPE++  + Y ++VDWW+ G ++YEM+ GLPP+Y ++   MY++IL  PL           D+L+ L+ ++P  RLG  N  DEI+ HPFF  I W  L+ K   PP+ P V S  D  N D EF KE    S+ +  L+   Q         F G++Y+   DE + +
Sbjct:  466 RDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRRLGV-NGTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFDQEFTKEKPIDSVVDEYLSASIQ-------KQFGGWTYIG--DEQLGD 668
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Yeast
Match: SCH9 (AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248])

HSP 1 Score: 166.007 bits (419), Expect = 1.659e-43
Identity = 94/217 (43.32%), Postives = 128/217 (58.99%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEP-YDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVK-LIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYV--PPIDENMAN 1877
            RDLKPENILLDA G+I L DFGL K  ++    T+TFCGT EYLAPE++  E  Y + VD+WS G +I+EM  G  PF++++  +MYQ+I    +    +  S      VK L+ +NPK RLG  +D  E++ HPFF+ IDW AL  K++ PPF P + S  D  N DPEF     S    +  +   T LS   +   F GF++V    IDE++ N
Sbjct:  537 RDLKPENILLDANGNIALCDFGLSKADLKDR--TNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFDPEFTTASTSYMNKHQPMMTATPLSPA-MQAKFAGFTFVDESAIDEHVNN 750
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700])

HSP 1 Score: 149.058 bits (375), Expect = 8.126e-40
Identity = 70/155 (45.16%), Postives = 104/155 (67.10%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLG-YKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVP 1700
            RDLKPENILLD  GHI +TDFG  K   +    T T CGTP+Y+APEV+  +PY++S+DWWSFG +IYEML G  PFY  +T + Y++ILN+ L         + D+L +LI ++  +RLG  +N  +++K HP+F ++ W  L+++ ++ P+ P
Sbjct:  209 RDLKPENILLDKNGHIKITDFGFAKYVPD---VTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEP 360
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649])

HSP 1 Score: 147.902 bits (372), Expect = 2.195e-39
Identity = 73/157 (46.50%), Postives = 104/157 (66.24%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLG-YKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQV 1706
            RDLKPENILLD  GHI +TDFG  K   +    T T CGTP+Y+APEV+  +PY++SVDWWSFG +IYEML G  PFY+ +T + Y+ ILN+ L           D+L KLI ++  ERLG  +N  +++K HP+F+++ W  L+ + ++ P+ P +
Sbjct:  210 RDLKPENILLDKNGHIKITDFGFAKYVPD---VTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPI 363
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Nematostella
Match: EDO37800 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEW2])

HSP 1 Score: 261.922 bits (668), Expect = 9.305e-81
Identity = 119/212 (56.13%), Postives = 159/212 (75.00%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGY-KNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENM 1871
            RDLKPENILLD++GHI+LTDFGLCKEGI+R GTTSTFCGTPEYLAPEV++K+ YD+SVDWW  G+V+YEM++GLPPFYS+DT +MY  IL+ PL LR N       IL  L++K+  +RLG  + DF++I+ H FF  I+W  LV + ++PP+ P VS   D+++ DPEF +EP+ GS+  S  +     SV+D DD+FVGF+YV P D+ +
Sbjct:  197 RDLKPENILLDSKGHIVLTDFGLCKEGIDRSGTTSTFCGTPEYLAPEVLRKQDYDKSVDWWCLGAVLYEMMYGLPPFYSRDTAEMYDNILHKPLRLRTNISQSARHILEGLLQKDKTKRLGSGEGDFEDIRTHSFFRSINWQQLVARGIEPPYNPNVSGQLDLKHFDPEFVREPVPGSVGKSADSNFVSASVDDPDDAFVGFTYVAPSDDTL 408
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Nematostella
Match: EDO41166 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S521])

HSP 1 Score: 172.94 bits (437), Expect = 1.492e-47
Identity = 87/207 (42.03%), Postives = 123/207 (59.42%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERL-GYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 1856
            RDLKPENILLDA GH+ LTDFGLCKE I     T TFCGT EY+APE++ +  + ++VDWWS G+++Y+ML G PPF + +  +   +IL   L +         D + KL++++P+ RL G   D + IK H FF  I W  L+ K+V+PPF P +S   D+   D +F ++    S  +S L+       E   + F GF+YV P
Sbjct:  191 RDLKPENILLDANGHVKLTDFGLCKESIFENSLTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMYDMLTGTPPFCADNRKKTIDKILKGKLIIPPYLTPEAKDFIRKLLKRHPQARLGGMAGDANPIKAHSFFRHICWEDLLAKKVEPPFRPSISGEEDVSQFDSKFTRQTPVDSPDDSMLS-------ESASNIFQGFTYVAP 390
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Nematostella
Match: EDO44938 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU22])

HSP 1 Score: 157.918 bits (398), Expect = 2.878e-41
Identity = 87/219 (39.73%), Postives = 124/219 (56.62%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFY--------SQDTHQ-MYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGY--KNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDS-FVGFSYVPPI 1859
            RDLK +N+LLD+ GHI LTD+G+CKEGI     TSTFCGTP Y+APE+++ E Y  SVDWW+ G ++YEML G  PF          Q+T   ++Q IL  P+ +  +     + IL   + KNP ERLG   +  F +I  H FF  + W  L  +QV PPF P+      + N DP+F  E +  +  + ++       +E +D + F GF Y+ P+
Sbjct:  345 RDLKLDNVLLDSDGHIKLTDYGMCKEGIRPGDVTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIVGSADNPDQNTEDYLFQVILEKPIRIPRSLSVKAASILKGYLNKNPTERLGCHPQTGFADITSHAFFRTVSWEQLEARQVTPPFKPRQEDPYGLENFDPQFTNEDVQFTPDDPKM-------LETIDQTEFEGFEYINPL 556
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Nematostella
Match: EDO31895 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWM6])

HSP 1 Score: 156.377 bits (394), Expect = 1.415e-40
Identity = 88/209 (42.11%), Postives = 118/209 (56.46%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKN-DFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEF-HKEPI-SGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 1856
            RDLKPENILLDA GH+ LTDFGL KE  E +  T +FCGT EY+APEV+ +  + ++ DWWS+G +++EML G  PF  +D       IL + L +          +L +L ++NP  RLG  +   ++IK HPFFS I+W  L  +++KPPF P      D    DPEF  K P  S ++P S    +           F GFSYV P
Sbjct:  133 RDLKPENILLDASGHVALTDFGLSKES-EHDQKTYSFCGTVEYMAPEVVNRRGHSQAADWWSYGVLMFEMLTGSLPFQGKDRKDTMNMILKAKLGMPQFLTPEAQSLLRQLFKRNPLNRLGAGDLGIEDIKKHPFFSTINWELLYKREIKPPFKPAAGRADDAFYFDPEFTSKTPQDSPAVPPSATCHQL----------FRGFSYVAP 330

HSP 2 Score: 67.781 bits (164), Expect = 7.941e-12
Identity = 36/81 (44.44%), Postives = 47/81 (58.02%), Query Frame = 3 
Query: 1239 RDLKPENIL-LDAQG---HIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPF 1469
            RDLKP NI+  D  G    + + DFG  K+     G   T C T  ++APEV+KK+ YD + D WS G ++Y ML GL PF
Sbjct:  472 RDLKPSNIMYADDSGTPESLRIVDFGFAKQMRATNGLLMTPCYTANFVAPEVLKKQGYDAACDIWSLGVLLYTMLSGLTPF 552
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Nematostella
Match: EDO35228 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM62])

HSP 1 Score: 148.288 bits (373), Expect = 1.118e-39
Identity = 76/181 (41.99%), Postives = 117/181 (64.64%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVIS-DILVKLIRKNPKERLG-YKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIP 1775
            RDLKPENILLD  GH+ LTDFG  KE  ++   T T CGTPEYLAPE+I+ + ++++VDWW+ G +IYEML G PPF+  +   +Y++IL+  +    +  +  + D++ KL+  +   RLG  KN  +++K H +F  IDW  ++ +++KPP  P++S   D RN D ++ +E   G+ P
Sbjct:  140 RDLKPENILLDRDGHVKLTDFGFAKEVHDK---TWTLCGTPEYLAPEIIQSKGHNKAVDWWALGILIYEMLVGYPPFFDDNPFGIYEKILSGKVEWPKHMDNTSAKDLIKKLLVHDRTRRLGSMKNGSEDVKNHKWFKVIDWNLVLQRKLKPPINPKISHPGDTRNFD-DYPEEDWRGAPP 316
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Medaka
Match: sgk3 (serum/glucocorticoid regulated kinase family member 3 [Source:NCBI gene;Acc:101156366])

HSP 1 Score: 260.766 bits (665), Expect = 6.517e-79
Identity = 125/211 (59.24%), Postives = 155/211 (73.46%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENM 1871
            RDLKPENILLD +GHI+LTDFGLCKEGI +  TT+TFCGTPEYLAPEV+KK PYD +VDWW  GSV+YEMLFGLPPFYS+DTH+MY  IL+ PL +R    S    +L  L+ K+  +RLG   DF+EIKVH FFS I+W  LV K++ PPF+P V+S  DI N DPEF +E +  SI  +Q +     SV + DD+F+GFSY PP D++ 
Sbjct:  281 RDLKPENILLDHEGHIVLTDFGLCKEGISQTDTTTTFCGTPEYLAPEVLKKHPYDNTVDWWCLGSVLYEMLFGLPPFYSRDTHEMYDNILHKPLAMRPGASSTAWSLLQGLLEKDGTQRLGSNGDFNEIKVHNFFSSINWDDLVQKKIPPPFIPNVTSCCDISNFDPEFTEENVPNSICWTQSHSVVNASVMEADDAFLGFSYAPPSDDSF 491
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Medaka
Match: SGK1 (serum/glucocorticoid regulated kinase 1 [Source:NCBI gene;Acc:101173276])

HSP 1 Score: 258.07 bits (658), Expect = 1.131e-78
Identity = 125/215 (58.14%), Postives = 159/215 (73.95%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHIILTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +   ++L  L++K+  +RLG  NDF EIK H FFS I+W  L  K++ PPF P V+   D+R+ DPEF  EP+S SI  S  +     S+++  ++FVGFSY P +D
Sbjct:  215 SLNIVY-RDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNISNSARNLLEGLLQKDRTKRLGCTNDFIEIKNHVFFSPINWDELNAKKITPPFNPNVTGPNDLRHFDPEFTDEPVSSSIGCSPDSALFTASIKEAAEAFVGFSYAPSMD 428
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Medaka
Match: SGK1 (serum/glucocorticoid regulated kinase 1 [Source:NCBI gene;Acc:101173276])

HSP 1 Score: 257.684 bits (657), Expect = 4.646e-77
Identity = 125/215 (58.14%), Postives = 159/215 (73.95%), Query Frame = 3 
Query: 1218 NLNISFIRDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPID 1862
            +LNI + RDLKPENILLD+QGHIILTDFGLCKE IE  GTTSTFCGTPEYLAPEV+ K+PYDR+VDWW  G+V+YEML+GLPPFYS++T +MY  ILN PL L+ N  +   ++L  L++K+  +RLG  NDF EIK H FFS I+W  L  K++ PPF P V+   D+R+ DPEF  EP+S SI  S  +     S+++  ++FVGFSY P +D
Sbjct:  338 SLNIVY-RDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNISNSARNLLEGLLQKDRTKRLGCTNDFIEIKNHVFFSPINWDELNAKKITPPFNPNVTGPNDLRHFDPEFTDEPVSSSIGCSPDSALFTASIKEAAEAFVGFSYAPSMD 551
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Medaka
Match: si:ch211-195b13.1 (serine/threonine-protein kinase Sgk1 [Source:NCBI gene;Acc:101162537])

HSP 1 Score: 250.751 bits (639), Expect = 5.450e-76
Identity = 116/206 (56.31%), Postives = 154/206 (74.76%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 1856
            RDLKPENILLD+QGHI+LTDFGLCKEG+E +GTTSTFCGTPEYLAPEV++K+ YDR+VDWW  GSV+YEML+GLPPFYS++T +MY  IL+    ++ N  +   ++L  L++K   +RLG K+DF E+K H FFS I+W  L+ K++ PPF+P VS   D+R+ DPEF + P+S S+ N  L   +  SV++   +F GFSY PP
Sbjct:  218 RDLKPENILLDSQGHIVLTDFGLCKEGLEADGTTSTFCGTPEYLAPEVLQKQAYDRTVDWWCLGSVLYEMLYGLPPFYSRNTAEMYNNILHKAPAMKPNVSNAGRELLEGLLQKERTKRLGAKDDFLELKYHSFFSPINWDDLMAKKITPPFIPSVSGPTDLRHFDPEFTQLPVSSSLCNDTLTVTS--SVKEAAGAFPGFSYGPP 421
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Medaka
Match: si:ch211-195b13.1 (serine/threonine-protein kinase Sgk1 [Source:NCBI gene;Acc:101162537])

HSP 1 Score: 250.366 bits (638), Expect = 6.555e-76
Identity = 116/206 (56.31%), Postives = 154/206 (74.76%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 1856
            RDLKPENILLD+QGHI+LTDFGLCKEG+E +GTTSTFCGTPEYLAPEV++K+ YDR+VDWW  GSV+YEML+GLPPFYS++T +MY  IL+    ++ N  +   ++L  L++K   +RLG K+DF E+K H FFS I+W  L+ K++ PPF+P VS   D+R+ DPEF + P+S S+ N  L   +  SV++   +F GFSY PP
Sbjct:  204 RDLKPENILLDSQGHIVLTDFGLCKEGLEADGTTSTFCGTPEYLAPEVLQKQAYDRTVDWWCLGSVLYEMLYGLPPFYSRNTAEMYNNILHKAPAMKPNVSNAGRELLEGLLQKERTKRLGAKDDFLELKYHSFFSPINWDDLMAKKITPPFIPSVSGPTDLRHFDPEFTQLPVSSSLCNDTLTVTS--SVKEAAGAFPGFSYGPP 407
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Planmine SMEST
Match: SMESG000022857.1 (SMESG000022857.1)

HSP 1 Score: 444.891 bits (1143), Expect = 2.840e-150
Identity = 213/213 (100.00%), Postives = 213/213 (100.00%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENMAN 1877
            RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENMAN
Sbjct:  266 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENMAN 478
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Planmine SMEST
Match: SMESG000024241.1 (SMESG000024241.1)

HSP 1 Score: 178.333 bits (451), Expect = 6.129e-48
Identity = 90/190 (47.37%), Postives = 120/190 (63.16%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYK-NDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQL 1805
            RDLK EN+LLD +GHI LTDFGLCKE +     T TFCGTPEYLAPEV+    Y RSVDWW  G V+YEM+ G  PFY+ D   +++ IL   + L  +      D+L +L+ KNP ER+G    D  EI +HPFF  IDW  L+ K++ PP+VP V  + D + I  EF +EP++ + P +  N  +Q+
Sbjct:  363 RDLKLENLLLDCEGHIKLTDFGLCKEEMYYGAFTKTFCGTPEYLAPEVLLDNDYSRSVDWWGLGVVMYEMMCGRLPFYNVDHEILFELILQENIKLPVHLTLSGQDMLSRLLIKNPNERIGGGVQDAVEIMIHPFFDNIDWDLLIKKKINPPWVPDVVDDKDTKYIPDEFAREPVTLTPPKNNNNYLSQI 552
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Planmine SMEST
Match: SMESG000024241.1 (SMESG000024241.1)

HSP 1 Score: 178.333 bits (451), Expect = 6.222e-48
Identity = 90/190 (47.37%), Postives = 120/190 (63.16%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYK-NDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQL 1805
            RDLK EN+LLD +GHI LTDFGLCKE +     T TFCGTPEYLAPEV+    Y RSVDWW  G V+YEM+ G  PFY+ D   +++ IL   + L  +      D+L +L+ KNP ER+G    D  EI +HPFF  IDW  L+ K++ PP+VP V  + D + I  EF +EP++ + P +  N  +Q+
Sbjct:  364 RDLKLENLLLDCEGHIKLTDFGLCKEEMYYGAFTKTFCGTPEYLAPEVLLDNDYSRSVDWWGLGVVMYEMMCGRLPFYNVDHEILFELILQENIKLPVHLTLSGQDMLSRLLIKNPNERIGGGVQDAVEIMIHPFFDNIDWDLLIKKKINPPWVPDVVDDKDTKYIPDEFAREPVTLTPPKNNNNYLSQI 553
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Planmine SMEST
Match: SMESG000046977.1 (SMESG000046977.1)

HSP 1 Score: 171.4 bits (433), Expect = 4.367e-47
Identity = 90/210 (42.86%), Postives = 133/210 (63.33%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQM-YQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFDEIKVHPFFSQ--IDWVALVNKQVKPPFVPQVSSNADIRNIDPEF-HKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPP 1856
            RDLKPEN+LLD  GH+ LTDFGL KE      +T+TFCGT EY+APE++++E +   VDWWS G+++++ML G PPF  + + Q+  ++IL +PL         +  ++  L+++NPKERLGYKND +EIK H FF +  I+W  +++++V+PPF P + S AD+   D  F +++PI        L+          +D F GFSYV P
Sbjct:   27 RDLKPENVLLDKCGHVKLTDFGLSKESAT---STNTFCGTIEYMAPEILRREGHTFVVDWWSLGTLLFDMLSGGPPFSQESSKQLTIEKILRAPLKFPMYFSLDVMGLIKGLLKRNPKERLGYKNDVEEIKSHIFFQKNDINWDDILSRKVEPPFKPDLKSEADVSCFDSTFTNQQPI--------LSPDDSTGTHISEDIFTGFSYVAP 225
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Planmine SMEST
Match: SMESG000039865.1 (SMESG000039865.1)

HSP 1 Score: 171.014 bits (432), Expect = 4.662e-46
Identity = 87/208 (41.83%), Postives = 128/208 (61.54%), Query Frame = 3 
Query: 1239 RDLKPENILLDAQGHIILTDFGLCKEGIEREGTTSTFCGTPEYLAPEVIKKEPYDRSVDWWSFGSVIYEMLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKERLGYKNDFD-EIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEFHKEPISGSIPNSQLNRRTQLSVEDVDDS-FVGFSYVPP 1856
            RDLK +NI+LD +GHI + DFG+CKEGI  + TT TFCGTP+Y+APE+IK +PY +SVDWW++G ++YEML G  PF  +D  +++  I    +    +       I   L+ K+PK+RLG     D +++ H FF +IDW  +  +QV+PP  P++    D+ N D EF KE        +QL    +L + ++D + F GFS+V P
Sbjct:  276 RDLKLDNIMLDHEGHIKIADFGMCKEGIFDDKTTRTFCGTPDYIAPEIIKYQPYGKSVDWWAYGVILYEMLAGQAPFDGEDEEELFNAITEHNVSYPKSMSKESVSICKGLLTKDPKKRLGSNRYGDRDVREHLFFRRIDWEKINARQVQPPNKPKIKDPRDVSNFDQEFTKE-------TAQLTPTDKLFIMNLDQTEFSGFSFVNP 476
The following BLAST results are available for this feature:
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SGK16.377e-8158.14serum/glucocorticoid regulated kinase 1 [Source:HG... [more]
SGK12.597e-8058.14serum/glucocorticoid regulated kinase 1 [Source:HG... [more]
SGK13.468e-8058.14serum/glucocorticoid regulated kinase 1 [Source:HG... [more]
SGK13.913e-8058.14serum/glucocorticoid regulated kinase 1 [Source:HG... [more]
SGK11.079e-7958.14serum/glucocorticoid regulated kinase 1 [Source:HG... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sgk-11.291e-6651.47Serine/threonine-protein kinase sgk-1 [Source:Uni... [more]
sgk-11.609e-6651.47Serine/threonine-protein kinase sgk-1 [Source:Uni... [more]
pkc-14.715e-4741.94Protein kinase C-like 1B [Source:UniProtKB/Swiss-... [more]
pkc-11.102e-4641.94Protein kinase C-like 1B [Source:UniProtKB/Swiss-... [more]
pkc-12.021e-4641.94Protein kinase C-like 1B [Source:UniProtKB/Swiss-... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Akt13.119e-4848.62gene:FBgn0010379 transcript:FBtr0083226[more]
Akt13.119e-4848.62gene:FBgn0010379 transcript:FBtr0344470[more]
Akt13.119e-4848.62gene:FBgn0010379 transcript:FBtr0344717[more]
Akt13.119e-4848.62gene:FBgn0010379 transcript:FBtr0083227[more]
Pkc98E3.447e-4840.43gene:FBgn0003093 transcript:FBtr0301516[more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sgk31.660e-7855.96serum/glucocorticoid regulated kinase family membe... [more]
sgk12.580e-7756.74serum/glucocorticoid regulated kinase 1 [Source:NC... [more]
sgk12.580e-7756.74serum/glucocorticoid regulated kinase 1 [Source:NC... [more]
si:ch211-195b13.19.073e-7656.25si:ch211-195b13.1 [Source:ZFIN;Acc:ZDB-GENE-030131... [more]
si:ch211-195b13.19.377e-7656.25si:ch211-195b13.1 [Source:ZFIN;Acc:ZDB-GENE-030131... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sgk16.252e-8157.67serum/glucocorticoid regulated kinase 1 [Source:NC... [more]
sgk18.649e-8157.67serum/glucocorticoid regulated kinase 1 [Source:NC... [more]
sgk11.199e-8057.67serum/glucocorticoid regulated kinase 1 [Source:NC... [more]
sgk11.830e-8057.67serum/glucocorticoid regulated kinase 1 [Source:NC... [more]
sgk12.182e-8057.67serum/glucocorticoid regulated kinase 1 [Source:NC... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Sgk12.242e-8258.60serum/glucocorticoid regulated kinase 1 [Source:MG... [more]
Sgk12.895e-8258.60serum/glucocorticoid regulated kinase 1 [Source:MG... [more]
Sgk13.491e-8258.60serum/glucocorticoid regulated kinase 1 [Source:MG... [more]
Sgk13.798e-8258.60serum/glucocorticoid regulated kinase 1 [Source:MG... [more]
Sgk11.955e-8058.60serum/glucocorticoid regulated kinase 1 [Source:MG... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9WVC6|SGK1_MOUSE2.025e-8158.60Serine/threonine-protein kinase Sgk1 OS=Mus muscul... [more]
sp|A7MB74|SGK1_BOVIN2.372e-8158.60Serine/threonine-protein kinase Sgk1 OS=Bos taurus... [more]
sp|Q6U1I9|SGK1_CHICK9.610e-8158.60Serine/threonine-protein kinase Sgk1 OS=Gallus gal... [more]
sp|Q9XT18|SGK1_RABIT1.517e-8058.14Serine/threonine-protein kinase Sgk1 OS=Oryctolagu... [more]
sp|Q06226|SGK1_RAT4.599e-8058.60Serine/threonine-protein kinase Sgk1 OS=Rattus nor... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
W5PZ922.472e-8058.60Non-specific serine/threonine protein kinase OS=Ov... [more]
H3CXL86.325e-8059.17Non-specific serine/threonine protein kinase OS=Te... [more]
A0A4W4FCW07.134e-8057.34Non-specific serine/threonine protein kinase OS=El... [more]
G1MC217.254e-8058.60Non-specific serine/threonine protein kinase OS=Ai... [more]
Q4SFC21.364e-7959.17Non-specific serine/threonine protein kinase OS=Te... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sgk32.857e-8056.88serum/glucocorticoid regulated kinase family membe... [more]
sgk31.582e-7856.42serum/glucocorticoid regulated kinase family membe... [more]
si:ch211-195b13.15.033e-7656.25serine/threonine-protein kinase Sgk1-like [Source:... [more]
si:ch211-195b13.18.044e-7656.25serine/threonine-protein kinase Sgk1-like [Source:... [more]
si:ch211-195b13.19.396e-7656.25serine/threonine-protein kinase Sgk1-like [Source:... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000006766.11.760e-7454.17pep scaffold:Pmarinus_7.0:GL478342:9725:27922:-1 g... [more]
ENSPMAT00000008480.13.791e-4745.86pep scaffold:Pmarinus_7.0:GL482122:191709:206473:1... [more]
sgk11.251e-4242.27serum/glucocorticoid regulated kinase 1 [Source:NC... [more]
ENSPMAT00000001814.11.461e-4141.71pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gen... [more]
PRKCD9.734e-3944.94protein kinase C delta [Source:HGNC Symbol;Acc:HGN... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
YPK11.150e-5347.55S/T protein kinase; phosphorylates, downregulates ... [more]
YPK22.220e-4944.13Protein kinase similar to S/T protein kinase Ypk1p... [more]
SCH91.659e-4343.32AGC family protein kinase; functional ortholog of ... [more]
TPK18.126e-4045.16cAMP-dependent protein kinase catalytic subunit; p... [more]
TPK32.195e-3946.50cAMP-dependent protein kinase catalytic subunit; p... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO378009.305e-8156.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO411661.492e-4742.03Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO449382.878e-4139.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO318951.415e-4042.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO352281.118e-3941.99Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sgk36.517e-7959.24serum/glucocorticoid regulated kinase family membe... [more]
SGK11.131e-7858.14serum/glucocorticoid regulated kinase 1 [Source:NC... [more]
SGK14.646e-7758.14serum/glucocorticoid regulated kinase 1 [Source:NC... [more]
si:ch211-195b13.15.450e-7656.31serine/threonine-protein kinase Sgk1 [Source:NCBI ... [more]
si:ch211-195b13.16.555e-7656.31serine/threonine-protein kinase Sgk1 [Source:NCBI ... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000022857.12.840e-150100.00SMESG000022857.1[more]
SMESG000024241.16.129e-4847.37SMESG000024241.1[more]
SMESG000024241.16.222e-4847.37SMESG000024241.1[more]
SMESG000046977.14.367e-4742.86SMESG000046977.1[more]
SMESG000039865.14.662e-4641.83SMESG000039865.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011173 ID=SMED30011173|Name=Non-specific serine/threonine protein kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=2034bp
CTTCCTTTTAACATTTAACTTATTTTCTATACGAATTTATGATAATTTTT
TTTCAAGTGTGAAAAAATTTGATCTTATATCGGTATTGGAAAAAAATTAA
ATGTTACATATACTCAATCGTGTTTAAACCTTTAAGTTTAAAGTCTAAAG
ATTTGAATAACTGATTATTAGAAAAATTCACTTTTAAATAAATTACTCTT
AGATTTGCGAGAAAAATTCATCTTAAAGCTAGTGGTAATAAATTTACCGA
AATTAGCGATTGCCTAGGGATTTTTACTAAACCTTCAAAGACCTCCTCAT
ATTGATTTAAGCACTTACTAAACGCAAAACGATGTAAGCTTTTCTGCTTA
AAGGATACTGCACGACTGAACTAAAATAATATGTAAACTGTGAAAATTGA
AAAGTTGAACACCCTTATTTTTAAAAAACCGGCTCTTCAGATATTATATA
AATGCAAAAAAATATTCCCAGTTTACCGGTTTTTTAAAGACTGAGTATTA
ATAAAAAAAACAACAAAAGTCATAAAAAGTGAATAGATTAGAAATATTTG
AAAAGTAGAATCGGTTAACAGCATGGTTTACAGTTCAATCTCTTGAGTTA
AATATAAGTAAATAAATAATTTACTAAAATTTATTTATAAAAAAACATTA
ATTTTAAACACAAAATAAAAATAAAGAATTCGATTATAAAATAAAGTAGT
GATAGTGACTGAAACTAGTTTCCAACCCCACTTCCATGGAGCACAAATGG
TTTGTTGAAGTAAGCTCTCATAAAAACACATTTCACTTAACCTTTTGTCG
TTCAAACTAGCTCCATCGTGCTTTTATGTCAAGAATTCTTGTAAGTTCTT
TATTAAATTCATCCTTAATGTCACAACAACTTTTTGAATGTTTGTTATTA
TTAGAACTGTGCAGAAAAATTGGATGTTTCTTTTAATAAATCGTGGGAAC
CTTTGATTTGTTGAGGTTCTAACTTTGGTCGCAAATATTAACCAGATAAA
CGAATCCAATGTTACTAATGTATTATAAAATACTGTAAGTTCATGAAAAT
TAATTTGCTTTTAATCTTTTGTTTCCCTTCGTGCAAAGTATTTGATGAGC
ACGCTGTGTCAATCAAAATTAACCGAATTTATTTTGTACTACAAACGGCT
GATATAGTTCCAAGTCAATTTTCCTAACATTCTCATTCTTTGATAATAAT
AATTTTGCATTGAACTTAATCTTAACATATCATTTATTAGAGATTTGAAG
CCAGAAAACATTTTACTAGATGCCCAGGGTCATATTATTTTGACCGATTT
TGGACTTTGCAAAGAGGGTATTGAACGAGAAGGAACAACGTCTACATTTT
GTGGAACACCTGAGTATTTAGCGCCTGAAGTTATAAAAAAGGAACCATAT
GATCGATCAGTTGATTGGTGGAGTTTCGGATCAGTAATTTATGAAATGCT
TTTTGGCTTACCACCCTTCTATTCTCAAGACACCCATCAAATGTATCAAC
GAATTCTTAACAGCCCTCTGCCACTAAGAGGAAACTGCCCATCAGTGATA
TCAGACATACTTGTAAAATTAATTAGAAAAAATCCTAAAGAGCGACTTGG
TTACAAAAATGACTTTGACGAAATAAAAGTACATCCTTTCTTTTCTCAAA
TCGATTGGGTTGCACTAGTCAATAAACAAGTGAAACCACCGTTTGTTCCC
CAGGTGTCATCCAATGCTGACATTAGAAATATTGATCCAGAATTCCATAA
AGAACCTATTTCGGGTTCAATTCCAAACTCACAGCTTAACAGAAGAACTC
AACTGAGTGTTGAAGATGTGGATGATTCGTTTGTAGGATTTTCATATGTT
CCTCCAATAGATGAAAACATGGCTAATTAAATGCTCGAGTTTTTATTAAT
TGGATTGAAATTTCTTAACGAATTTCAAAGGATTTGTGGAAACTTGGTTT
TTAGTTATTTTTGATTTTTATTTTTGAAATAAATTTTTAGAATTTTTACT
TAGCAGATATTTATTATATCTTGTTTTAAATGCT
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protein sequence of SMED30011173-orf-1

>SMED30011173-orf-1 ID=SMED30011173-orf-1|Name=SMED30011173-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=145bp
MLFGLPPFYSQDTHQMYQRILNSPLPLRGNCPSVISDILVKLIRKNPKER
LGYKNDFDEIKVHPFFSQIDWVALVNKQVKPPFVPQVSSNADIRNIDPEF
HKEPISGSIPNSQLNRRTQLSVEDVDDSFVGFSYVPPIDENMAN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0035091phosphatidylinositol binding
GO:0005524ATP binding
GO:0004672protein kinase activity
GO:0004674protein serine/threonine kinase activity
GO:0000166nucleotide binding
GO:0004712protein serine/threonine/tyrosine kinase activity
GO:0005515protein binding
GO:0016301kinase activity
GO:0016740transferase activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR000961AGC-kinase_C
IPR017892Pkinase_C
IPR011009Kinase-like_dom_sf
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0006915apoptotic process
GO:0006974cellular response to DNA damage stimulus
GO:0010765positive regulation of sodium ion transport
GO:0016310phosphorylation
GO:0018105peptidyl-serine phosphorylation
GO:0032869cellular response to insulin stimulus
GO:0032880regulation of protein localization
GO:0035556intracellular signal transduction
GO:0048812neuron projection morphogenesis
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005737cytoplasm
GO:0005739mitochondrion
GO:0005783endoplasmic reticulum
GO:0005789endoplasmic reticulum membrane
GO:0005829cytosol
GO:0005886plasma membrane
GO:0016020membrane
GO:0016607nuclear speck
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000961AGC-kinase, C-terminalSMARTSM00133pkinase_C_6coord: 67..136
e-value: 2.8E-14
score: 63.4
IPR000961AGC-kinase, C-terminalPROSITEPS51285AGC_KINASE_CTERcoord: 67..144
score: 15.17
NoneNo IPR availableGENE3DG3DSA:3.30.200.20coord: 86..110
e-value: 1.3E-29
score: 105.2
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 1..85
e-value: 1.3E-29
score: 105.2
NoneNo IPR availablePANTHERPTHR24351RIBOSOMAL PROTEIN S6 KINASEcoord: 1..141
NoneNo IPR availablePANTHERPTHR24351:SF197coord: 1..141
IPR017892Protein kinase, C-terminalPFAMPF00433Pkinase_Ccoord: 87..134
e-value: 2.0E-4
score: 22.0
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 1..66
score: 8.514
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 1..122