Malectin domain-containing protein

Overview
NameMalectin domain-containing protein
Smed IDSMED30011146
Length (bp)1141
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Malectin domain-containing protein (SMED30011146) t-SNE clustered cells

Violin plots show distribution of expression levels for Malectin domain-containing protein (SMED30011146) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Malectin domain-containing protein (SMED30011146) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Malectin domain-containing protein (SMED30011146) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30011146

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30011146h1SMcG0005579 Contig4405uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30011146h1SMcG0005579 Contig4405newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30011146h1SMcG0020587 Contig4405uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30011146h1SMcG0020587 Contig4405newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30011146h1SMcG0020587 dd_Smed_v4_1880_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30011146h1SMcG0020587 dd_Smed_v4_1880_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior sideSMED30011146h1SMcG0020587 dd_Smed_v4_1880_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30011146h1SMcG0020587 dd_Smed_v4_1880_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Malectin domain-containing protein vs. Ensembl Human
Match: MLEC (malectin [Source:HGNC Symbol;Acc:HGNC:28973])

HSP 1 Score: 225.713 bits (574), Expect = 4.103e-71
Identity = 132/261 (50.57%), Postives = 179/261 (68.58%), Query Frame = 3 
Query:  138 IIWAVNCGGDAHVDSHGVRYQRDTLN--VGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
            +IWAVN GG+AHVD HG+ +++D L   VG  SDYG  + I R + +DQILYQTERY+   FGYE+PI  +G+Y+LVLKF+EV+F    QKVFDV LN  H+VV+ LDIF +VG  TAHDEIIP+ ++ GKL V+GE S  +  K+ +EF+KG  DNPKV A+Y+M GT++D+PKL P         +   E    E EE + D  SN +     Q  + R+ SGP++P+PY++D++S MF PI +A G F+P LFCLC+L
Sbjct:   48 VIWAVNAGGEAHVDVHGIHFRKDPLEGRVGRASDYGMKLPILRSNPEDQILYQTERYNEETFGYEVPIKEEGDYVLVLKFAEVYFAQSQQKVFDVRLNG-HVVVKDLDIFDRVGHSTAHDEIIPMSIRKGKLSVQGEVST-FTGKLYIEFVKGYYDNPKVCALYIMAGTVDDVPKLQP---------HPGLEKKEEEEEEEEYDEGSNLKK----QTNKNRVQSGPRTPNPYASDNSSLMF-PILVAFGVFIPTLFCLCRL 292
[Close]
BLAST of Malectin domain-containing protein vs. Ensembl Human
Match: MLEC (malectin [Source:HGNC Symbol;Acc:HGNC:28973])

HSP 1 Score: 164.081 bits (414), Expect = 3.711e-49
Identity = 80/138 (57.97%), Postives = 105/138 (76.09%), Query Frame = 3 
Query:  252 INRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPP 665
            I R + +DQILYQTERY+   FGYE+PI  +G+Y+LVLKF+EV+F    QKVFDV LN  H+VV+ LDIF +VG  TAHDEIIP+ ++ GKL V+GE S  +  K+ +EF+KG  DNPKV A+Y+M GT++D+PKL P
Sbjct:    5 ILRSNPEDQILYQTERYNEETFGYEVPIKEEGDYVLVLKFAEVYFAQSQQKVFDVRLNG-HVVVKDLDIFDRVGHSTAHDEIIPMSIRKGKLSVQGEVS-TFTGKLYIEFVKGYYDNPKVCALYIMAGTVDDVPKLQP 140
[Close]
BLAST of Malectin domain-containing protein vs. Ensembl Human
Match: MLEC (malectin [Source:HGNC Symbol;Acc:HGNC:28973])

HSP 1 Score: 112.464 bits (280), Expect = 1.246e-28
Identity = 51/94 (54.26%), Postives = 69/94 (73.40%), Query Frame = 3 
Query:  138 IIWAVNCGGDAHVDSHGVRYQRDTLN--VGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFD 413
            +IWAVN GG+AHVD HG+ +++D L   VG  SDYG  + I R + +DQILYQTERY+   FGYE+PI  +G+Y+LVLKF+EV+F    QK++ 
Sbjct:   48 VIWAVNAGGEAHVDVHGIHFRKDPLEGRVGRASDYGMKLPILRSNPEDQILYQTERYNEETFGYEVPIKEEGDYVLVLKFAEVYFAQSQQKMYQ 141
[Close]
BLAST of Malectin domain-containing protein vs. Ensembl Human
Match: MLEC (malectin [Source:HGNC Symbol;Acc:HGNC:28973])

HSP 1 Score: 108.227 bits (269), Expect = 1.788e-27
Identity = 52/92 (56.52%), Postives = 69/92 (75.00%), Query Frame = 3 
Query:  312 NFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIK 587
             FGYE+PI  +G+Y+LVLKF+EV+F    QKVFDV LN  H+VV+ LDIF +VG  TAHDEIIP+ ++ GKL V+GE S  +  K+ +EF+K
Sbjct:    5 TFGYEVPIKEEGDYVLVLKFAEVYFAQSQQKVFDVRLNG-HVVVKDLDIFDRVGHSTAHDEIIPMSIRKGKLSVQGEVS-TFTGKLYIEFVK 94
[Close]
BLAST of Malectin domain-containing protein vs. Ensembl Celegans
Match: F44E2.10 (pep chromosome:WBcel235:III:8829493:8831109:-1 gene:WBGene00018423.1 transcript:F44E2.10.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F44E2.10)

HSP 1 Score: 158.688 bits (400), Expect = 1.493e-45
Identity = 87/219 (39.73%), Postives = 129/219 (58.90%), Query Frame = 3 
Query:   30 SISLIGTIFSMHVLLYCTLNIYQLFIFVSQSNAIG---EIIWAVNCGGDAHVDSHGVRYQRDTLNVGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKV-GRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAF 674
            SIS     F M + L   L I  L + VS +  +     ++ AVNCGG   + ++G+ Y  DT   G++SD+G     N    DD  +YQTER+   +F Y++PI  DGEY+++LKFSEV+F    +K+F++ +N+ H+ V+ LDIF    GRG AHD  IP+ +K   + V G S + Y  K+ +E  KG  DNPK+N   +++GT+ED+P  PP  F
Sbjct:    7 SISFQIRAFQMSIQL---LLISFLIVVVSSAKTVNLKNRVVAAVNCGGPDALGAYGIEYSADTSEDGVSSDHGMQYSFNNAEVDDMEIYQTERWSKESFSYDVPISEDGEYVIILKFSEVYFQKAGEKIFNIRINS-HLAVKNLDIFDAAGGRGFAHDVYIPVVIKGSSISVSGHSRE-YKGKVIIELSKGPHDNPKLNGYAILRGTVEDLPS-PPEKF 219
[Close]
BLAST of Malectin domain-containing protein vs. Ensembl Fly
Match: CG9257 (gene:FBgn0032916 transcript:FBtr0081465)

HSP 1 Score: 198.749 bits (504), Expect = 3.090e-60
Identity = 101/215 (46.98%), Postives = 143/215 (66.51%), Query Frame = 3 
Query:   21 FNNSISLIGTIFSMHVLLYCTLNIYQLFIFVSQSNAIGEIIWAVNCGGDAHVDSHGVRYQRDTLN-VGINSDYGKSMV-INRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKL 659
            F N +   G    M VLL   L    +  F +      ++I+AVN GGD H D +GV+Y  D L  VGI SDYGK ++ I R+   D++LY+TERYHT  FGY++P   DG+Y L++KF EV+F AP +KVFDV+LN +H VV +LDI+ +VGRG+AHDEI+  K+ +G+L  +GE SD+   ++ ++FIKG  DNPK+NA  L+KG I  +P++
Sbjct:   27 FRNYLRASGQRTWMSVLLVLVL----MGTFTAAEPL--KVIYAVNAGGDEHTDLNGVQYDADPLKGVGIASDYGKHLLMIGRVQEHDEVLYRTERYHTTTFGYDLPSDGDGDYALIMKFCEVYFDAPQKKVFDVLLNRKHTVVRQLDIYNEVGRGSAHDEIVYFKINNGRLNYEGEVSDVRNGRLRLDFIKGALDNPKINAFALLKGDISQVPRM 235
[Close]
BLAST of Malectin domain-containing protein vs. Ensembl Zebrafish
Match: mlec (malectin [Source:NCBI gene;Acc:569613])

HSP 1 Score: 226.483 bits (576), Expect = 1.150e-71
Identity = 141/294 (47.96%), Postives = 188/294 (63.95%), Query Frame = 3 
Query:   66 VLLYCT--LNIYQLFIFV------SQSNAIGE-IIWAVNCGGDAHVDSHGVRYQRDTLN--VGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
            V L+C   L I  L++ V      S + ++ E +IWAVN GGD H D HG+++++D L   VG  SDYG  + I R   +DQILYQTERY+   FGYE+PI  +G+YILV+K++EV+F    QKVFDV LN  H+VV+ LDIF +VG  TAHDEI+P  +K GKL V GE S  +  K++VEF+KG  DNPK+ A+Y+MKG +ED+PKL P     H      EE    E E    +    S +  P  P R    SGP++P+PY+TD++S MF PI +A G F+P LFCLC+L
Sbjct:    4 VTLHCAARLVIAALWLLVEVCRAESGAQSLAERVIWAVNAGGDTHTDVHGIQFKKDPLEGKVGKASDYGVRLPILRSSPEDQILYQTERYNEDTFGYEVPIREEGDYILVMKYAEVYFAQSQQKVFDVRLNG-HVVVKDLDIFDRVGHSTAHDEIVPFSIKRGKLSVHGEVST-FNGKLTVEFVKGYYDNPKICALYVMKGKLEDVPKLQP-----HPGLEKREEEEEEEEEGEGPEGEKKSASTSPKNPVR----SGPRTPNPYATDNSSLMF-PILVAFGVFIPTLFCLCRL 285
[Close]
BLAST of Malectin domain-containing protein vs. Ensembl Xenopus
Match: pnisr (PNN-interacting serine/arginine-rich protein [Source:Xenbase;Acc:XB-GENE-977237])

HSP 1 Score: 228.409 bits (581), Expect = 2.636e-72
Identity = 134/261 (51.34%), Postives = 179/261 (68.58%), Query Frame = 3 
Query:  138 IIWAVNCGGDAHVDSHGVRYQRDTLN--VGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
            +IWAVN GG++HVD HG+ Y++D L   VG  SDYG  + I R + +DQ+LYQTERY+  +FGY+IPI  +GEY+LVLKF+EV+F    QKVFDV +N  H VV+ LDIF +VG  TAHDEIIP+ +K GKL V+GE S  +  K+SVEF+KG  DNPKV A+Y+MKGT +D+PKL P                  E EE +E+  S S+     Q  + R+ SGP++P+PY++D++S MF PI +A G F+P LFCLC+L
Sbjct:   37 VIWAVNAGGESHVDVHGIHYRKDPLEGRVGRASDYGMKLPILRSNPEDQVLYQTERYNEDSFGYDIPIKEEGEYVLVLKFAEVYFAQSQQKVFDVRVNG-HTVVKDLDIFDRVGHSTAHDEIIPISIKKGKLSVQGEVST-FTGKLSVEFVKGYYDNPKVCALYIMKGTADDVPKLQP----------HPGLEKKEEEEEEEEEEGSTSKK----QSNKNRVQSGPRTPNPYASDNSSLMF-PILVAFGVFIPTLFCLCRL 280
[Close]
BLAST of Malectin domain-containing protein vs. Ensembl Xenopus
Match: pnisr (PNN-interacting serine/arginine-rich protein [Source:Xenbase;Acc:XB-GENE-977237])

HSP 1 Score: 228.409 bits (581), Expect = 2.897e-72
Identity = 134/261 (51.34%), Postives = 179/261 (68.58%), Query Frame = 3 
Query:  138 IIWAVNCGGDAHVDSHGVRYQRDTLN--VGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
            +IWAVN GG++HVD HG+ Y++D L   VG  SDYG  + I R + +DQ+LYQTERY+  +FGY+IPI  +GEY+LVLKF+EV+F    QKVFDV +N  H VV+ LDIF +VG  TAHDEIIP+ +K GKL V+GE S  +  K+SVEF+KG  DNPKV A+Y+MKGT +D+PKL P                  E EE +E+  S S+     Q  + R+ SGP++P+PY++D++S MF PI +A G F+P LFCLC+L
Sbjct:   39 VIWAVNAGGESHVDVHGIHYRKDPLEGRVGRASDYGMKLPILRSNPEDQVLYQTERYNEDSFGYDIPIKEEGEYVLVLKFAEVYFAQSQQKVFDVRVNG-HTVVKDLDIFDRVGHSTAHDEIIPISIKKGKLSVQGEVST-FTGKLSVEFVKGYYDNPKVCALYIMKGTADDVPKLQP----------HPGLEKKEEEEEEEEEEGSTSKK----QSNKNRVQSGPRTPNPYASDNSSLMF-PILVAFGVFIPTLFCLCRL 282
[Close]
BLAST of Malectin domain-containing protein vs. Ensembl Mouse
Match: Mlec (malectin [Source:MGI Symbol;Acc:MGI:1924015])

HSP 1 Score: 223.787 bits (569), Expect = 1.923e-70
Identity = 130/261 (49.81%), Postives = 178/261 (68.20%), Query Frame = 3 
Query:  138 IIWAVNCGGDAHVDSHGVRYQRDTLN--VGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
            +IWAVN GG+AHVD HG+ +++D L   VG  SDYG  + I R   +DQILYQTERY+   FGYE+P+  +G+Y+LVLKF+EV+F    QKVFDV LN  H+VV+ LDIF +VG  TAHDEIIP+ ++ GKL V+GE S  +  K+ +EF+KG  DNPKV A+Y++ GT++D+PKL P         +   E    E EE + D  SN +     Q  + R+ SGP++P+PY++D++S MF PI +A G F+P LFCLC+L
Sbjct:   47 VIWAVNAGGEAHVDVHGIHFRKDPLEGRVGRASDYGMKLPILRSTPEDQILYQTERYNEETFGYEVPVKEEGDYVLVLKFAEVYFAQSQQKVFDVRLNG-HVVVKDLDIFDRVGHSTAHDEIIPMSIRKGKLSVRGEVST-FTGKLYIEFVKGYYDNPKVCALYILAGTVDDVPKLQP---------HPGLEKKEEEEEEEEYDEGSNLKR----QTNKNRVQSGPRTPNPYASDNSSLMF-PILVAFGVFIPTLFCLCRL 291
[Close]
BLAST of Malectin domain-containing protein vs. UniProt/SwissProt
Match: sp|A9C3P0|MLEC_DANRE (Malectin OS=Danio rerio OX=7955 GN=mlec PE=3 SV=1)

HSP 1 Score: 226.483 bits (576), Expect = 8.685e-71
Identity = 141/294 (47.96%), Postives = 188/294 (63.95%), Query Frame = 3 
Query:   66 VLLYCT--LNIYQLFIFV------SQSNAIGE-IIWAVNCGGDAHVDSHGVRYQRDTLN--VGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
            V L+C   L I  L++ V      S + ++ E +IWAVN GGD H D HG+++++D L   VG  SDYG  + I R   +DQILYQTERY+   FGYE+PI  +G+YILV+K++EV+F    QKVFDV LN  H+VV+ LDIF +VG  TAHDEI+P  +K GKL V GE S  +  K++VEF+KG  DNPK+ A+Y+MKG +ED+PKL P     H      EE    E E    +    S +  P  P R    SGP++P+PY+TD++S MF PI +A G F+P LFCLC+L
Sbjct:    4 VTLHCAARLVIAALWLLVEVCRAESGAQSLAERVIWAVNAGGDTHTDVHGIQFKKDPLEGKVGKASDYGVRLPILRSSPEDQILYQTERYNEDTFGYEVPIREEGDYILVMKYAEVYFAQSQQKVFDVRLNG-HVVVKDLDIFDRVGHSTAHDEIVPFSIKRGKLSVHGEVST-FNGKLTVEFVKGYYDNPKICALYVMKGKLEDVPKLQP-----HPGLEKREEEEEEEEEGEGPEGEKKSASTSPKNPVR----SGPRTPNPYATDNSSLMF-PILVAFGVFIPTLFCLCRL 285
[Close]
BLAST of Malectin domain-containing protein vs. UniProt/SwissProt
Match: sp|Q14165|MLEC_HUMAN (Malectin OS=Homo sapiens OX=9606 GN=MLEC PE=1 SV=1)

HSP 1 Score: 225.713 bits (574), Expect = 1.970e-70
Identity = 132/261 (50.57%), Postives = 179/261 (68.58%), Query Frame = 3 
Query:  138 IIWAVNCGGDAHVDSHGVRYQRDTLN--VGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
            +IWAVN GG+AHVD HG+ +++D L   VG  SDYG  + I R + +DQILYQTERY+   FGYE+PI  +G+Y+LVLKF+EV+F    QKVFDV LN  H+VV+ LDIF +VG  TAHDEIIP+ ++ GKL V+GE S  +  K+ +EF+KG  DNPKV A+Y+M GT++D+PKL P         +   E    E EE + D  SN +     Q  + R+ SGP++P+PY++D++S MF PI +A G F+P LFCLC+L
Sbjct:   48 VIWAVNAGGEAHVDVHGIHFRKDPLEGRVGRASDYGMKLPILRSNPEDQILYQTERYNEETFGYEVPIKEEGDYVLVLKFAEVYFAQSQQKVFDVRLNG-HVVVKDLDIFDRVGHSTAHDEIIPMSIRKGKLSVQGEVST-FTGKLYIEFVKGYYDNPKVCALYIMAGTVDDVPKLQP---------HPGLEKKEEEEEEEEYDEGSNLKK----QTNKNRVQSGPRTPNPYASDNSSLMF-PILVAFGVFIPTLFCLCRL 292
[Close]
BLAST of Malectin domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5FVQ4|MLEC_RAT (Malectin OS=Rattus norvegicus OX=10116 GN=Mlec PE=2 SV=1)

HSP 1 Score: 225.328 bits (573), Expect = 3.172e-70
Identity = 131/261 (50.19%), Postives = 178/261 (68.20%), Query Frame = 3 
Query:  138 IIWAVNCGGDAHVDSHGVRYQRDTLN--VGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
            +IWAVN GG+AHVD HG+ +++D L   VG  SDYG  + I R   +DQILYQTERY+   FGYE+P+  +G+Y+LVLKF+EV+F    QKVFDV LN  H+VV+ LDIF +VG  TAHDEIIP+ ++ GKL V+GE S  +  K+ +EF+KG  DNPKV A+Y+M GT++D+PKL P         +   E    E EE + D  SN +     Q  + R+ SGP++P+PY++D++S MF PI +A G F+P LFCLC+L
Sbjct:   47 VIWAVNAGGEAHVDVHGIHFRKDPLEGRVGRASDYGMKLPILRSTPEDQILYQTERYNEETFGYEVPVKEEGDYVLVLKFAEVYFAQSQQKVFDVRLNG-HVVVKDLDIFDRVGHSTAHDEIIPMSIRKGKLSVQGEVS-TFTGKLYIEFVKGYYDNPKVCALYIMAGTVDDVPKLQP---------HPGLEKKEEEEEEEEYDEGSNLKR----QTNKNRVQSGPRTPNPYASDNSSLMF-PILVAFGVFIPTLFCLCRL 291
[Close]
BLAST of Malectin domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6INX3|MLECA_XENLA (Malectin-A OS=Xenopus laevis OX=8355 GN=mlec-a PE=1 SV=1)

HSP 1 Score: 224.557 bits (571), Expect = 3.578e-70
Identity = 132/262 (50.38%), Postives = 179/262 (68.32%), Query Frame = 3 
Query:  135 EIIWAVNCGGDAHVDSHGVRYQRDTLN--VGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
            ++IWAVN GG++HVD HG+ Y++D L   VG  SDYG  + I R + +DQ+LYQTERY+  +FGY+IPI  +GEY+LVLKF+EV+F    QKVFDV +N  H VV+ LDIF +VG  TAHDEIIP+ +K GKL V+GE S  +  K+SVEF+KG  DNPKV A+++MKGT +D+P L P                  E EE +E+  S S+     Q  + R+ SGP++P+PY++D++S MF PI +A G F+P LFCLC+L
Sbjct:   32 KVIWAVNAGGESHVDVHGIHYRKDPLEGRVGRASDYGMKLPILRSNPEDQVLYQTERYNEDSFGYDIPIKEEGEYVLVLKFAEVYFAQSQQKVFDVRVNG-HTVVKDLDIFDRVGHSTAHDEIIPISIKKGKLSVQGEVST-FTGKLSVEFVKGYYDNPKVCALFIMKGTADDVPMLQP----------HPGLEKKEEEEEEEEEEGSTSKK----QINKNRVQSGPRTPNPYASDNSSLMF-PILVAFGVFIPTLFCLCRL 276
[Close]
BLAST of Malectin domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8AVF4|MLECB_XENLA (Malectin-B OS=Xenopus laevis OX=8355 GN=mlec-b PE=2 SV=2)

HSP 1 Score: 224.557 bits (571), Expect = 4.252e-70
Identity = 130/262 (49.62%), Postives = 180/262 (68.70%), Query Frame = 3 
Query:  135 EIIWAVNCGGDAHVDSHGVRYQRDTLN--VGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
            +++WAVN GG++HVD HG+ Y++D L   VG  SDYG  + I R + +DQ+LYQTERY+  +FGY+IPI  +GEY++VLKF+EV+F    QKVFD+ +N  H VV+ LDIF +VG  TAHDEIIP+ +K GKL V+GE S  +  K+SVEF+KG  DNPKV A+Y+MKGT +D+P+L P                  E EE +E+  S S+     Q  + R+ SGP++P+PY++D++S MF PI +A G F+P LFCLC+L
Sbjct:   32 KVMWAVNAGGESHVDVHGIHYRKDPLEGRVGRASDYGMKLPILRSNPEDQVLYQTERYNEDSFGYDIPIKEEGEYVIVLKFAEVYFAQSQQKVFDIRVNG-HTVVKDLDIFDRVGHSTAHDEIIPISIKKGKLSVQGEVST-FTGKLSVEFVKGYYDNPKVCALYIMKGTADDVPQLQP----------HPGLEKKEEEEEEEEEEGSPSKK----QSNKNRVQSGPRTPNPYASDNSSLMF-PILVAFGVFIPTLFCLCRL 276
[Close]
BLAST of Malectin domain-containing protein vs. TrEMBL
Match: A0A210QMS2 (Malectin OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT00943 PE=4 SV=1)

HSP 1 Score: 307.76 bits (787), Expect = 4.223e-100
Identity = 158/299 (52.84%), Postives = 208/299 (69.57%), Query Frame = 3 
Query:   33 ISLIGTIFSMHVLLYC-----TLNIYQLFIFVSQSNAIGEIIWAVNCGGDAHVDSHGVRYQRDTLNVGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
            +S  G +++     +C        I  +   V+QS +IGE+IWAVNCGG+AH D +G+RY+ D+L VGI+SDYGK+++++R+   DQILYQTERYH + FGYEIP+  DGEY+L LKF EVWFT+PNQKVFDV LN EH VV+ LDI+ KVGRG AHDE+I   ++ GKL V GE+S +  +K+ VEF+KGD DNPK+NAIYLMKGTI+D+PKLP L                  +E   E+         PD+P + R  SGPK  DPY++DDTS+M LP+ +A+GAF+P+LFCLCKL
Sbjct:    2 LSACGRVYANMTFCFCHRKHMLFLICTILTLVTQSLSIGEVIWAVNCGGEAHTDINGIRYETDSLKVGISSDYGKTLMVSRVVAQDQILYQTERYHMSTFGYEIPLSGDGEYVLALKFCEVWFTSPNQKVFDVTLNGEHTVVDELDIYSKVGRGVAHDELIEFTIRSGKLKVNGETSKI-NSKLLVEFMKGDYDNPKINAIYLMKGTIDDVPKLPSLP----------------GTETTREEEEVEDEEDSPDRPSKARRPSGPKVKDPYASDDTSTMLLPVIIALGAFIPLLFCLCKL 283
[Close]
BLAST of Malectin domain-containing protein vs. TrEMBL
Match: A0A2T7PDX7 (Malectin domain-containing protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_07038 PE=4 SV=1)

HSP 1 Score: 305.064 bits (780), Expect = 4.834e-99
Identity = 160/284 (56.34%), Postives = 203/284 (71.48%), Query Frame = 3 
Query:   63 HVLLYCTLNIYQLFIFVSQSNAIGEIIWAVNCGGDAHVDSHGVRYQRDTLNVGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
            HVL    L     F  +S +  IG++IWAVNCGG+AH D HG+RYQ D L VG  S+YGK+++I R+   DQ+LYQTERYH + F Y+IPI  DG+Y+LV+KFSEVWFT+PNQKVFDV+LN EH VV  LDIF KVGRG AHDEI+P  +K GKL V GE+S +   KIS+EF+KGD DNPKVNAIY++KGT+EDIPKLP LA                   E +E+    S+N   ++P ++R  SGP++ DPY+ DDTS+M LP+ +AIGAF+P+LFCLCKL
Sbjct:   20 HVLFSSVL----AFCLLSNAVGIGDVIWAVNCGGEAHTDIHGIRYQADPLEVGFASEYGKNLIIQRVVPQDQVLYQTERYHLSTFSYDIPIWKDGDYVLVMKFSEVWFTSPNQKVFDVVLNGEHTVVSELDIFAKVGRGVAHDEIVPFSIKGGKLRVNGETSQIDGKKISLEFVKGDLDNPKVNAIYVVKGTVEDIPKLPQLA-------------GGETPPEEEEEDDDESQN---NKPSKQRRPSGPRAKDPYAADDTSTMLLPVFVAIGAFIPLLFCLCKL 283
[Close]
BLAST of Malectin domain-containing protein vs. TrEMBL
Match: A0A385UIK0 (Malectin OS=Azumapecten farreri OX=106299 PE=2 SV=1)

HSP 1 Score: 305.064 bits (780), Expect = 9.117e-99
Identity = 155/275 (56.36%), Postives = 201/275 (73.09%), Query Frame = 3 
Query:   90 IYQLFIFVSQSNAIGEIIWAVNCGGDAHVDSHGVRYQRDTLNVGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
            I  +   V+QS  IGE+IWAVNCGG++H D +G+RY+ D+L VGI+SDYGK+++++R+   DQILYQTERYH + FGYEIP+  DGEY+LVLKF EVWFT+PNQKVFDV LN EH VV+ LDI+ KVGRG AHDE+I   ++ GKL V GE+S +  +K+ VEF+KGD DNPK+NAIYLMKGTI+D+PKLP L                  +E   E+   +     PD+P + R  SGPK  DPY++DDTS+M LP+ +A+GAF+P+LFCLCKL
Sbjct:   45 ICTILSLVTQSLGIGEVIWAVNCGGESHTDINGIRYETDSLKVGISSDYGKTLMVSRVVAQDQILYQTERYHMSTFGYEIPLSGDGEYVLVLKFCEVWFTSPNQKVFDVTLNGEHTVVDELDIYSKVGRGVAHDELIEFTIRSGKLKVNGETSKI-NSKLLVEFMKGDYDNPKINAIYLMKGTIDDVPKLPSLP----------------GTETTREEEEVDEEEDSPDRPSKARRPSGPKVKDPYASDDTSTMLLPVIIALGAFIPLLFCLCKL 302
[Close]
BLAST of Malectin domain-containing protein vs. TrEMBL
Match: V4AVB5 (Malectin domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_103588 PE=4 SV=1)

HSP 1 Score: 295.434 bits (755), Expect = 2.242e-95
Identity = 160/282 (56.74%), Postives = 196/282 (69.50%), Query Frame = 3 
Query:   69 LLYCTLNIYQLFIFVSQSNAIGEIIWAVNCGGDAHVDSHGVRYQRDTLNVGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
            +L+C L I  LF    Q+    E+ WAVNCGG +H D HG+RYQ DTL +G  SDYGKS++I R+   DQILYQTERYH + FGY+IP+  DG+Y+LVLKFSEVWFTAP+QKVFDV+LN EH +V  LDIF KVGRG AHDEIIP  +K+GKL V GE+S +   KISVEF+KGD DNPKVNAIY++KG I+D+P L PL    +  D+  EE                       +P + R  SGPK+ DPY+ DDTS M LP+ +AIGAFLP+LFCLCKL
Sbjct:   21 ILFCFLCIALLF---GQTFCNPEVAWAVNCGGSSHTDVHGIRYQADTLQIGFASDYGKSLLIQRVVPQDQILYQTERYHRSTFGYDIPVTKDGDYVLVLKFSEVWFTAPSQKVFDVILNGEHTIVNELDIFAKVGRGVAHDEIIPFTIKNGKLRVNGETSQI-DGKISVEFLKGDLDNPKVNAIYVIKGNIDDVPMLAPLPGGENSQDDIEEEEEEENEMP---------------KPSKSRRPSGPKAKDPYAADDTSVMLLPVFIAIGAFLPLLFCLCKL 283
[Close]
BLAST of Malectin domain-containing protein vs. TrEMBL
Match: A0A0B7ADM8 (Malectin domain-containing protein (Fragment) OS=Arion vulgaris OX=1028688 GN=ORF108542 PE=4 SV=1)

HSP 1 Score: 293.508 bits (750), Expect = 1.683e-94
Identity = 147/279 (52.69%), Postives = 194/279 (69.53%), Query Frame = 3 
Query:   78 CTLNIYQLFIFVSQSNAIGEIIWAVNCGGDAHVDSHGVRYQRDTLNVGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
            C + +  +   V Q     E++WAVNCGG+ H DSH + YQ D L+VG +SDYG+S+ I R+ + DQILYQTERYH + FGY+IPI  DG Y+LVLKFSEVWF APNQKVFD++LN EH +V  LDIF +VGRG AHDEI+P  V+ GKL+V  E+S +  +KIS+EFIKGD DNPKVNAIY+ KGTI+D+P+LPP+  P                    E+      ++P ++ +  R  SGP+  DPY+++DTS+M LP+  AIGAF+P+L+CLCKL
Sbjct:   28 CLVTLVVVCSLVLQPVNALEVVWAVNCGGEEHTDSHDIHYQADPLDVGSSSDYGRSLFIQRVSSQDQILYQTERYHASTFGYDIPISKDGNYVLVLKFSEVWFGAPNQKVFDIVLNGEHTIVSELDIFARVGRGVAHDEIVPFSVRSGKLHVNEETSHIDGSKISIEFIKGDLDNPKVNAIYVAKGTIDDVPQLPPILSPD-----------------AAEENDDEDEDSPSEKLQATRKPSGPRVKDPYASEDTSAMLLPVFAAIGAFIPLLYCLCKL 289
[Close]
BLAST of Malectin domain-containing protein vs. Ensembl Cavefish
Match: mlec (malectin [Source:NCBI gene;Acc:103029697])

HSP 1 Score: 225.328 bits (573), Expect = 2.777e-71
Identity = 133/262 (50.76%), Postives = 176/262 (67.18%), Query Frame = 3 
Query:  135 EIIWAVNCGGDAHVDSHGVRYQRDTLN--VGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
             +IWAVN GG+AH D+HG+++++D L   VG  SDYG  + I R   +DQ+LYQTERY+   FGY++PI  +G+YILVLKF+EV+F    QKVFDV LN  H+VV+ LDIF +VG  TAHDEI+P  +K GKL V+GE S  +  K+ +EFIKG  DNPKV A+Y+MKG  ED+PKL P     H      EE    E  E+ +D    S ++ P  P R    SGP++P+PY+ D++S MF PI +A G F+P LFCLC+L
Sbjct:   36 RVIWAVNAGGEAHTDTHGIQFRKDPLEGKVGKASDYGMRLPILRSSPEDQVLYQTERYNEDTFGYDVPIRDEGDYILVLKFAEVYFAQSQQKVFDVRLNG-HVVVKDLDIFDRVGHSTAHDEIVPFSIKRGKLSVQGEVS-TFNGKLVIEFIKGYYDNPKVCALYVMKGKPEDVPKLQP-----HPGLEKREEDEEEEEVEVGDDGVKKSTSSSPKNPVR----SGPRTPNPYAADNSSLMF-PILVAFGVFIPTLFCLCRL 285
[Close]
BLAST of Malectin domain-containing protein vs. Ensembl Nematostella
Match: EDO47413 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLY6])

HSP 1 Score: 218.009 bits (554), Expect = 2.666e-69
Identity = 119/249 (47.79%), Postives = 158/249 (63.45%), Query Frame = 3 
Query:   72 LYCTLNIYQLFI--FVSQSNAIGEIIWAVNCGGDAHVDSHGVRYQRDTLNVGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPK 812
            L C L I+ L I  F  +  + GE+++AVN GG AH D +GV YQ D L VG++SDYGK + I R+   DQILYQTERYH +NFGY +PI  +GEY+LVLKF EV+F AP  KVFDV +N+ H V++ LDI+ KVGRG AHDE +P  ++D +L   G +   +   + VEFIKG  DNPK+NA+ +MKGT+ED+PKLP L  P                   +E+          ++PK++R TSGPK
Sbjct:    4 LVCEL-IFVLVIGVFSGEVWSTGEVVYAVNSGGPAHTDLNGVHYQADKLTVGVSSDYGKMLTIGRVAPPDQILYQTERYHLSNFGYTVPIKENGEYVLVLKFCEVYFQAPRLKVFDVSINS-HPVIQGLDIYEKVGRGIAHDEYVPFTIRDNQLIHNGNTMP-FTGTVYVEFIKGVYDNPKINAMLIMKGTLEDVPKLPALPGPQD----------------EEEEKEEAEDTFKEEKPKKQRKTSGPK 233
[Close]
BLAST of Malectin domain-containing protein vs. Ensembl Medaka
Match: mlec (malectin [Source:NCBI gene;Acc:101164729])

HSP 1 Score: 222.246 bits (565), Expect = 4.120e-70
Identity = 129/266 (48.50%), Postives = 173/266 (65.04%), Query Frame = 3 
Query:  123 NAIGEIIWAVNCGGDAHVDSHGVRYQRDTLN--VGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
            N    +IWAVN GG+AHVD HG+ +++D L   VG  SDYG  + I R   +DQILYQTERY+   FGY+IPI  +G YILVLKFSEV+F    QKVFDV LN  H+VV+ LDIF +VG  TAHDEI+P  +  GKL V+GE S  +  K++VEF+KG  DNPK+ A+Y+MKGT+ D+PKL P       H    +     + ++ + +        P     + R+ SGP++P+PY+ D++S MF PI +A G F+P LFCLC+L
Sbjct:   32 NLAERVIWAVNAGGEAHVDVHGIHFKKDPLEGKVGKASDYGVRLPILRSSPEDQILYQTERYNEDTFGYDIPIREEGNYILVLKFSEVYFAQSQQKVFDVRLNG-HVVVKDLDIFDRVGHSTAHDEIVPFSINRGKLTVQGEVST-FNGKLAVEFVKGYYDNPKICALYVMKGTLGDVPKLQP-------HPGLEKHDEGEDDDDDESEGGEEGGKKPVLSRSKNRVQSGPRTPNPYAADNSSLMF-PILVAFGVFIPTLFCLCRL 287
[Close]
BLAST of Malectin domain-containing protein vs. Planmine SMEST
Match: SMESG000010440.1 (SMESG000010440.1)

HSP 1 Score: 516.538 bits (1329), Expect = 0.000e+0
Identity = 283/285 (99.30%), Postives = 285/285 (100.00%), Query Frame = 3 
Query:   60 MHVLLYCTLNIYQLFIFVSQSNAIGEIIWAVNCGGDAHVDSHGVRYQRDTLNVGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKLPPLAFPSHGXXXXXXXXXXXXXXXXXXXYSSNSRNAPPDQPKRKRLTSGPKXXXXXXXXXXXXMFLPIAMAIGAFLPILFCLCKL 914
            MHVLLYCTLNIYQLFIFVSQSNAIGEIIWAVNCGGDAHVDSHGVRYQRDTLNVGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIED+PKLPPLAFPSHGHDNSHEESHHPESEE+DEDYSSNSRNAPPDQPKRKRLTSGPKSPDPYSTDDTSSMFLPIAMAIGAFLPILFCLCKL
Sbjct:    1 MHVLLYCTLNIYQLFIFVSQSNAIGEIIWAVNCGGDAHVDSHGVRYQRDTLNVGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYILVLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLKVKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDVPKLPPLAFPSHGHDNSHEESHHPESEEMDEDYSSNSRNAPPDQPKRKRLTSGPKSPDPYSTDDTSSMFLPIAMAIGAFLPILFCLCKL 285
The following BLAST results are available for this feature:
BLAST of Malectin domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
MLEC4.103e-7150.57malectin [Source:HGNC Symbol;Acc:HGNC:28973][more]
MLEC3.711e-4957.97malectin [Source:HGNC Symbol;Acc:HGNC:28973][more]
MLEC1.246e-2854.26malectin [Source:HGNC Symbol;Acc:HGNC:28973][more]
MLEC1.788e-2756.52malectin [Source:HGNC Symbol;Acc:HGNC:28973][more]
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BLAST of Malectin domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
F44E2.101.493e-4539.73pep chromosome:WBcel235:III:8829493:8831109:-1 gen... [more]
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BLAST of Malectin domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG92573.090e-6046.98gene:FBgn0032916 transcript:FBtr0081465[more]
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BLAST of Malectin domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mlec1.150e-7147.96malectin [Source:NCBI gene;Acc:569613][more]
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BLAST of Malectin domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pnisr2.636e-7251.34PNN-interacting serine/arginine-rich protein [Sour... [more]
pnisr2.897e-7251.34PNN-interacting serine/arginine-rich protein [Sour... [more]
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BLAST of Malectin domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Mlec1.923e-7049.81malectin [Source:MGI Symbol;Acc:MGI:1924015][more]
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BLAST of Malectin domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A9C3P0|MLEC_DANRE8.685e-7147.96Malectin OS=Danio rerio OX=7955 GN=mlec PE=3 SV=1[more]
sp|Q14165|MLEC_HUMAN1.970e-7050.57Malectin OS=Homo sapiens OX=9606 GN=MLEC PE=1 SV=1[more]
sp|Q5FVQ4|MLEC_RAT3.172e-7050.19Malectin OS=Rattus norvegicus OX=10116 GN=Mlec PE=... [more]
sp|Q6INX3|MLECA_XENLA3.578e-7050.38Malectin-A OS=Xenopus laevis OX=8355 GN=mlec-a PE=... [more]
sp|Q8AVF4|MLECB_XENLA4.252e-7049.62Malectin-B OS=Xenopus laevis OX=8355 GN=mlec-b PE=... [more]
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BLAST of Malectin domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A210QMS24.223e-10052.84Malectin OS=Mizuhopecten yessoensis OX=6573 GN=KP7... [more]
A0A2T7PDX74.834e-9956.34Malectin domain-containing protein OS=Pomacea cana... [more]
A0A385UIK09.117e-9956.36Malectin OS=Azumapecten farreri OX=106299 PE=2 SV=... [more]
V4AVB52.242e-9556.74Malectin domain-containing protein OS=Lottia gigan... [more]
A0A0B7ADM81.683e-9452.69Malectin domain-containing protein (Fragment) OS=A... [more]
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BLAST of Malectin domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mlec2.777e-7150.76malectin [Source:NCBI gene;Acc:103029697][more]
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BLAST of Malectin domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Malectin domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Malectin domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO474132.666e-6947.79Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Malectin domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mlec4.120e-7048.50malectin [Source:NCBI gene;Acc:101164729][more]
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BLAST of Malectin domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000010440.10.000e+099.30SMESG000010440.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011146 ID=SMED30011146|Name=Malectin domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1141bp
CTAATATTTAATGACTTGGTTTTAACAATTCAATTTCGCTAATAGGGACT
ATTTTTTCAATGCATGTTTTATTGTATTGTACGCTCAATATTTATCAGTT
ATTTATTTTTGTCTCCCAATCGAATGCAATAGGGGAAATTATTTGGGCTG
TTAATTGTGGTGGTGATGCACACGTGGATTCTCATGGTGTACGATATCAA
CGAGATACTCTAAATGTTGGAATAAATTCTGACTATGGCAAAAGTATGGT
AATCAATAGAATTCATACAGATGATCAAATCCTATATCAAACGGAACGCT
ATCACACAGCAAATTTTGGTTATGAAATTCCCATTCCACACGATGGAGAA
TATATTTTAGTTTTAAAATTTTCCGAAGTTTGGTTCACTGCTCCTAATCA
AAAGGTATTTGACGTCATGTTGAATGCGGAACACATTGTGGTTGAGAGGT
TGGACATATTTGGTAAAGTCGGCCGAGGAACTGCTCACGACGAGATAATC
CCACTGAAAGTAAAAGACGGGAAATTGTATGTCAAAGGCGAATCATCTGA
TCTCTATTATAACAAAATATCAGTTGAATTTATCAAGGGGGACCGAGATA
ACCCGAAAGTTAATGCCATTTATTTGATGAAAGGAACAATCGAAGACATA
CCAAAGCTGCCACCGCTAGCATTTCCTAGTCACGGTCATGACAATAGTCA
TGAGGAATCTCACCATCCAGAGTCGGAAGAATTGGACGAGGATTACTCCA
GTAACAGCCGCAATGCTCCACCAGATCAACCGAAGCGTAAGAGATTAACG
AGTGGTCCCAAATCTCCTGATCCGTATTCCACGGATGACACGTCATCAAT
GTTTCTACCAATCGCGATGGCAATTGGTGCATTTTTGCCAATTCTTTTCT
GTTTGTGCAAGCTCTGAGTTTGATTGCCATTTCTGCCAGTGATTAGGCGG
CACCACCAAATGGGTTTCGCGACCGCTGTGCTGTGTTTAATATATATGTA
ATGCTGAGGATGATAGTAATTTGTTGTTGCTGTTTGGAGGAATGTTTCTA
TTTATTTCTATTATTATTTCTTTAATAAATGTATCTTGTATTACTATTGG
ATGACTGGGCTCGTTATCATTTGTGACTGTGTGTATTCATC
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protein sequence of SMED30011146-orf-1

>SMED30011146-orf-1 ID=SMED30011146-orf-1|Name=SMED30011146-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=286bp
MHVLLYCTLNIYQLFIFVSQSNAIGEIIWAVNCGGDAHVDSHGVRYQRDT
LNVGINSDYGKSMVINRIHTDDQILYQTERYHTANFGYEIPIPHDGEYIL
VLKFSEVWFTAPNQKVFDVMLNAEHIVVERLDIFGKVGRGTAHDEIIPLK
VKDGKLYVKGESSDLYYNKISVEFIKGDRDNPKVNAIYLMKGTIEDIPKL
PPLAFPSHGHDNSHEESHHPESEELDEDYSSNSRNAPPDQPKRKRLTSGP
KSPDPYSTDDTSSMFLPIAMAIGAFLPILFCLCKL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0030246carbohydrate binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000070intestinal phagocyte
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
PLANA:0003001lateral region of the whole animal
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR039155MLEC
IPR021720Malectin_dom
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:2.60.120.430coord: 23..195
e-value: 2.4E-64
score: 218.1
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 209..230
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 208..258
NoneNo IPR availablePANTHERPTHR13460:SF0MALECTINcoord: 21..283
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..23
score: 0.51
NoneNo IPR availableTMHMMTMhelixcoord: 261..283
IPR021720Malectin domainPFAMPF11721Malectincoord: 28..187
e-value: 2.0E-43
score: 148.4
IPR039155MalectinPANTHERPTHR13460UNCHARACTERIZEDcoord: 21..283