GLI-1

Overview
NameGLI-1 (ACZ64514.1)
Smed IDSMED30011047
Length (bp)3085
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of GLI-1 (SMED30011047) t-SNE clustered cells

Violin plots show distribution of expression levels for GLI-1 (SMED30011047) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of GLI-1 (SMED30011047) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for GLI-1 (SMED30011047) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30011047

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
epidermisSMED30011047h1SMcG0012543 SMED30011047smed_20140614PMID:29100657
Cheng et al., 2018		whole organism asexual adult fluorescence in situ hybridization evidence
neoblastSMED30011047h1SMcG0012543 SMED30011047smed_20140614PMID:29100657
Cheng et al., 2018		whole organism asexual adult fluorescence in situ hybridization evidence
X1 cellSMED30011047h1SMcG0012543 SMED30011047smed_20140614PMID:29100657
Cheng et al., 2018		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30011047h1SMcG0012543 dd_Smed_v4_7470_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30011047h1SMcG0012543 dd_Smed_v4_7470_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30011047h1SMcG0012543 dd_Smed_v4_7470_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
enteric muscle cellSMED30011047h1SMcG0012543 dd_Smed_v4_7470_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of GLI-1 vs. Ensembl Human
Match: GLI3 (GLI family zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:4319])

HSP 1 Score: 280.796 bits (717), Expect = 1.697e-77
Identity = 127/184 (69.02%), Postives = 142/184 (77.17%), Query Frame = 2 
Query: 1307 QEGDPD--------FTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGE 1834
            +EGD D          ETNCHW  C + FDTQ +LV HI+  HI G  K+ FVC+W DC R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G+
Sbjct:  463 EEGDKDESKQEPEVIYETNCHWEGCAREFDTQEQLVHHINNDHIHGE-KKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGD 645
[Close]
BLAST of GLI-1 vs. Ensembl Human
Match: GLI3 (GLI family zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:4319])

HSP 1 Score: 280.411 bits (716), Expect = 1.946e-77
Identity = 127/184 (69.02%), Postives = 142/184 (77.17%), Query Frame = 2 
Query: 1307 QEGDPD--------FTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGE 1834
            +EGD D          ETNCHW  C + FDTQ +LV HI+  HI G  K+ FVC+W DC R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G+
Sbjct:  404 EEGDKDESKQEPEVIYETNCHWEGCAREFDTQEQLVHHINNDHIHGE-KKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGD 586
[Close]
BLAST of GLI-1 vs. Ensembl Human
Match: GLI2 (GLI family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:4318])

HSP 1 Score: 278.87 bits (712), Expect = 6.422e-77
Identity = 123/174 (70.69%), Postives = 139/174 (79.89%), Query Frame = 2 
Query: 1307 QEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMK 1828
            QE +    ETNCHW DC K +DTQ +LV HI+  HI G  K+ FVC+W+ C R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C+K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPY+CK+ GC KRYTDPSSLRKHVKT HGP  +  KK +
Sbjct:  428 QEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGE-KKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQR 600
[Close]
BLAST of GLI-1 vs. Ensembl Human
Match: GLI2 (GLI family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:4318])

HSP 1 Score: 278.87 bits (712), Expect = 6.422e-77
Identity = 123/174 (70.69%), Postives = 139/174 (79.89%), Query Frame = 2 
Query: 1307 QEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMK 1828
            QE +    ETNCHW DC K +DTQ +LV HI+  HI G  K+ FVC+W+ C R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C+K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPY+CK+ GC KRYTDPSSLRKHVKT HGP  +  KK +
Sbjct:  428 QEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGE-KKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQR 600
[Close]
BLAST of GLI-1 vs. Ensembl Human
Match: GLI1 (GLI family zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:4317])

HSP 1 Score: 266.544 bits (680), Expect = 3.556e-74
Identity = 121/176 (68.75%), Postives = 136/176 (77.27%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQS 1858
            ET+C W+ C + FD+Q +LV HI++ HI G  K+ FVC W  C R  RPFKAQYMLVVHMRRHTGEKPH+CTF  C K YSRLENLKTH+RSHTGEKPY CE  GC KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP  +  K+ +G+    R  S
Sbjct:  106 ETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKE-FVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPS 280
[Close]
BLAST of GLI-1 vs. Ensembl Celegans
Match: tra-1 (Sex-determining transformer protein 1 [Source:UniProtKB/Swiss-Prot;Acc:P34708])

HSP 1 Score: 215.698 bits (548), Expect = 3.120e-57
Identity = 102/182 (56.04%), Postives = 126/182 (69.23%), Query Frame = 2 
Query: 1313 GDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQ--TFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYAD-KKMKGESWSDR 1849
            GD D T   C W  C  +F T   LV H+   H+  + ++   + C+W+ C R+   FKA YML+VH+RRHTGEKP++C +P C K YSRLENLKTH R+HTGEKPY+CEF  C KAFSNASDRAKHQNRTHSN KPY C++  C K YTDPSSLRKH+K  HG   Y   KK +  ++S+R
Sbjct:  204 GDHDLT---CRWKSCNSSFQTLKALVDHVQESHVQSTEQEHHAWRCEWEGCDRN-ETFKALYMLIVHVRRHTGEKPNKCEYPGCGKEYSRLENLKTHRRTHTGEKPYKCEFADCEKAFSNASDRAKHQNRTHSNLKPYSCQIPQCTKSYTDPSSLRKHIKAVHGDDEYEKAKKSRPANYSNR 381
[Close]
BLAST of GLI-1 vs. Ensembl Celegans
Match: ztf-14 (Zinc finger putative Transcription Factor family [Source:UniProtKB/TrEMBL;Acc:Q93902])

HSP 1 Score: 157.147 bits (396), Expect = 1.905e-40
Identity = 80/152 (52.63%), Postives = 93/152 (61.18%), Query Frame = 2 
Query: 1340 CHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNH 1795
            C W+ C  T D +A    H+   HI    K    C+W+ C RS   FK  Y    H R HT +K + C    C KRY RLENLKTH R+HTGEKPY C  P C+K+F+NASDR+KH  RTHSN KPY C    CA  YTDPSSLRKHVK+ H
Sbjct:  233 CLWDGCTLTLDDRATFFVHVDN-HIQ---KNEVNCKWRYCERS---FKQTYEFTAHKRTHTKQKLYCCEV--CPKRYGRLENLKTHRRTHTGEKPYHCNVPNCNKSFTNASDRSKHSKRTHSNEKPYCCDFGSCACAYTDPSSLRKHVKSKH 375
[Close]
BLAST of GLI-1 vs. Ensembl Celegans
Match: ref-2 (REgulator of Fusion [Source:UniProtKB/TrEMBL;Acc:Q7JNM3])

HSP 1 Score: 147.517 bits (371), Expect = 7.837e-39
Identity = 86/191 (45.03%), Postives = 106/191 (55.50%), Query Frame = 2 
Query: 1232 HFQLSNVDKLIEKHSDNSYKLCSKPQEGDPDFTETNCHWND----CVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTN 1792
            HF  + VD  I  ++  SY        GD    +  C W      C+       EL  HIS+ HI+   K  FVC WK C R  + FKA+Y LV HMR HTGE+P  C    CNK ++R ENLK H R H+GEKP++C   GC K F+N+SDR KH +  HS+ KPY C    C K YT PSSLRKH K +
Sbjct:   59 HFLPAQVDPFIYPNTLGSYG-------GD---KQVQCLWETNGQVCMHVCQNSGELSTHISSNHITHDSK--FVCLWKGCDREFKMFKAKYKLVNHMRVHTGERPFLCDV--CNKVFARSENLKIHKRIHSGEKPFQCTHNGCTKLFANSSDRKKHMH-VHSSHKPYSCMYPDCGKTYTHPSSLRKHTKVH 234
[Close]
BLAST of GLI-1 vs. Ensembl Celegans
Match: ref-2 (REgulator of Fusion [Source:UniProtKB/TrEMBL;Acc:Q7JNM3])

HSP 1 Score: 147.132 bits (370), Expect = 8.814e-39
Identity = 86/191 (45.03%), Postives = 106/191 (55.50%), Query Frame = 2 
Query: 1232 HFQLSNVDKLIEKHSDNSYKLCSKPQEGDPDFTETNCHWND----CVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTN 1792
            HF  + VD  I  ++  SY        GD    +  C W      C+       EL  HIS+ HI+   K  FVC WK C R  + FKA+Y LV HMR HTGE+P  C    CNK ++R ENLK H R H+GEKP++C   GC K F+N+SDR KH +  HS+ KPY C    C K YT PSSLRKH K +
Sbjct:   46 HFLPAQVDPFIYPNTLGSYG-------GD---KQVQCLWETNGQVCMHVCQNSGELSTHISSNHITHDSK--FVCLWKGCDREFKMFKAKYKLVNHMRVHTGERPFLCDV--CNKVFARSENLKIHKRIHSGEKPFQCTHNGCTKLFANSSDRKKHMH-VHSSHKPYSCMYPDCGKTYTHPSSLRKHTKVH 221
[Close]
BLAST of GLI-1 vs. Ensembl Celegans
Match: ref-2 (REgulator of Fusion [Source:UniProtKB/TrEMBL;Acc:Q7JNM3])

HSP 1 Score: 147.132 bits (370), Expect = 8.814e-39
Identity = 86/191 (45.03%), Postives = 106/191 (55.50%), Query Frame = 2 
Query: 1232 HFQLSNVDKLIEKHSDNSYKLCSKPQEGDPDFTETNCHWND----CVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTN 1792
            HF  + VD  I  ++  SY        GD    +  C W      C+       EL  HIS+ HI+   K  FVC WK C R  + FKA+Y LV HMR HTGE+P  C    CNK ++R ENLK H R H+GEKP++C   GC K F+N+SDR KH +  HS+ KPY C    C K YT PSSLRKH K +
Sbjct:   46 HFLPAQVDPFIYPNTLGSYG-------GD---KQVQCLWETNGQVCMHVCQNSGELSTHISSNHITHDSK--FVCLWKGCDREFKMFKAKYKLVNHMRVHTGERPFLCDV--CNKVFARSENLKIHKRIHSGEKPFQCTHNGCTKLFANSSDRKKHMH-VHSSHKPYSCMYPDCGKTYTHPSSLRKHTKVH 221
[Close]
BLAST of GLI-1 vs. Ensembl Fly
Match: ci (gene:FBgn0004859 transcript:FBtr0306168)

HSP 1 Score: 287.73 bits (735), Expect = 1.240e-80
Identity = 146/251 (58.17%), Postives = 175/251 (69.72%), Query Frame = 2 
Query: 1322 DFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSD---RCQSKQDGYSSGKYNWDHQLSMKNSS-ENFIGTHSNSLHTPSSSTQTTNAW------SDNL---SPNDVAFNI 2035
            DF ETNCHW  C   F TQ ELVKHI+  HI  + K+ FVC+W+DC R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C K YSRLENLKTH+RSHTGEKPY CE+PGC KAFSNASDRAKHQNRTHSN KPY+CK  GC KRYTDPSSLRKHVKT HG + YA+KK KG   +D   R Q     ++  ++N D     ++S     +GT S S+ + S  + + +        SD+L   SP+D+A N+
Sbjct:  329 DFIETNCHWRSCRIEFITQDELVKHINNDHIQ-TNKKAFVCRWEDCTRGEKPFKAQYMLVVHMRRHTGEKPHKCTFEGCFKAYSRLENLKTHLRSHTGEKPYTCEYPGCSKAFSNASDRAKHQNRTHSNEKPYICKAPGCTKRYTDPSSLRKHVKTVHGAEFYANKKHKGLPLNDANSRLQQNNSRHNLQEHNIDSSPCSEDSHLGKMLGTSSPSIKSESDISSSNHHLVNGVRASDSLLTYSPDDLAENL 578
[Close]
BLAST of GLI-1 vs. Ensembl Fly
Match: ci (gene:FBgn0004859 transcript:FBtr0089178)

HSP 1 Score: 287.73 bits (735), Expect = 2.573e-80
Identity = 146/251 (58.17%), Postives = 175/251 (69.72%), Query Frame = 2 
Query: 1322 DFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSD---RCQSKQDGYSSGKYNWDHQLSMKNSS-ENFIGTHSNSLHTPSSSTQTTNAW------SDNL---SPNDVAFNI 2035
            DF ETNCHW  C   F TQ ELVKHI+  HI  + K+ FVC+W+DC R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C K YSRLENLKTH+RSHTGEKPY CE+PGC KAFSNASDRAKHQNRTHSN KPY+CK  GC KRYTDPSSLRKHVKT HG + YA+KK KG   +D   R Q     ++  ++N D     ++S     +GT S S+ + S  + + +        SD+L   SP+D+A N+
Sbjct:  447 DFIETNCHWRSCRIEFITQDELVKHINNDHIQ-TNKKAFVCRWEDCTRGEKPFKAQYMLVVHMRRHTGEKPHKCTFEGCFKAYSRLENLKTHLRSHTGEKPYTCEYPGCSKAFSNASDRAKHQNRTHSNEKPYICKAPGCTKRYTDPSSLRKHVKTVHGAEFYANKKHKGLPLNDANSRLQQNNSRHNLQEHNIDSSPCSEDSHLGKMLGTSSPSIKSESDISSSNHHLVNGVRASDSLLTYSPDDLAENL 696
[Close]
BLAST of GLI-1 vs. Ensembl Fly
Match: lmd (gene:FBgn0039039 transcript:FBtr0084364)

HSP 1 Score: 202.601 bits (514), Expect = 2.011e-53
Identity = 93/168 (55.36%), Postives = 114/168 (67.86%), Query Frame = 2 
Query: 1295 CSKPQEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHG 1798
            C    E + +     C W  C + F  Q   V+HI   H+     + F C W DC R  +PF A+Y L++HMR H+GEKP++C FP CNK +SRLENLK H RSHTGE+PY C++ GC KAFSN+SDRAKHQ RTH +TKPY C++ GC KRYTDPSSLRKHVK NH 
Sbjct:  422 CDPEAEPENEVIPLICRWTGCDEEFPHQQAFVEHIEKCHVDVRKGEDFSCFWLDCPRRYKPFNARYKLLIHMRVHSGEKPNKCPFPGCNKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKHQ-RTHYDTKPYACQLPGCTKRYTDPSSLRKHVK-NHA 587
[Close]
BLAST of GLI-1 vs. Ensembl Fly
Match: sug (gene:FBgn0033782 transcript:FBtr0331985)

HSP 1 Score: 184.111 bits (466), Expect = 2.928e-51
Identity = 88/151 (58.28%), Postives = 107/151 (70.86%), Query Frame = 2 
Query: 1340 CHWNDCVKTFDTQAELVKHISTIH-ISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKT 1789
            C+W DC + FDT   L +H++  H I+      + C+W+ C RS R F A+Y ++VH R HT EKPH+C    C K +SR ENLK HIRSH+GEKPY+C F GC KA+SN+SDR KH  RTHS  KPY+CKV GC KRYTDPSSLRKHVKT
Sbjct:   68 CNWTDCDRVFDTLDALAQHVTQRHAIASLTDGLYYCRWRGCQRSERGFNARYKMLVHTRTHTKEKPHRCHL--CEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKH-TRTHSMEKPYMCKVAGCQKRYTDPSSLRKHVKT 215
[Close]
BLAST of GLI-1 vs. Ensembl Fly
Match: sug (gene:FBgn0033782 transcript:FBtr0087789)

HSP 1 Score: 184.496 bits (467), Expect = 9.264e-51
Identity = 88/151 (58.28%), Postives = 107/151 (70.86%), Query Frame = 2 
Query: 1340 CHWNDCVKTFDTQAELVKHISTIH-ISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKT 1789
            C+W DC + FDT   L +H++  H I+      + C+W+ C RS R F A+Y ++VH R HT EKPH+C    C K +SR ENLK HIRSH+GEKPY+C F GC KA+SN+SDR KH  RTHS  KPY+CKV GC KRYTDPSSLRKHVKT
Sbjct:  130 CNWTDCDRVFDTLDALAQHVTQRHAIASLTDGLYYCRWRGCQRSERGFNARYKMLVHTRTHTKEKPHRCHL--CEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKH-TRTHSMEKPYMCKVAGCQKRYTDPSSLRKHVKT 277
[Close]
BLAST of GLI-1 vs. Ensembl Zebrafish
Match: gli1 (GLI family zinc finger 1 [Source:ZFIN;Acc:ZDB-GENE-030321-1])

HSP 1 Score: 283.878 bits (725), Expect = 6.827e-79
Identity = 126/169 (74.56%), Postives = 139/169 (82.25%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGES 1837
            ETNCHW  C K FDTQ +LV HI+  HI G  K+ FVC WKDC R  RPFKAQYMLVVHMRRHTGEKPH+CTF  CNK YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPY+CK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G++
Sbjct:  301 ETNCHWESCSKEFDTQEQLVHHINNEHIHGE-KKEFVCHWKDCSREQRPFKAQYMLVVHMRRHTGEKPHKCTFEGCNKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPEAHITKKHRGDT 468
[Close]
BLAST of GLI-1 vs. Ensembl Zebrafish
Match: gli3 (GLI family zinc finger 3 [Source:ZFIN;Acc:ZDB-GENE-041111-162])

HSP 1 Score: 282.722 bits (722), Expect = 2.096e-78
Identity = 123/170 (72.35%), Postives = 142/170 (83.53%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESW 1840
            ETNCHW+ C + FDTQ +LV HI+  HI G  K+ FVC+W++C R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C+K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +GE++
Sbjct:  485 ETNCHWDGCCREFDTQEQLVHHINNDHIHGEKKE-FVCRWEECSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGETY 653
[Close]
BLAST of GLI-1 vs. Ensembl Zebrafish
Match: gli2b (GLI family zinc finger 2b [Source:ZFIN;Acc:ZDB-GENE-050523-1])

HSP 1 Score: 278.485 bits (711), Expect = 1.583e-77
Identity = 125/180 (69.44%), Postives = 143/180 (79.44%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDG 1870
            ETNCHW  C K +DTQ +LV HI+  HI G  K+ FVC+W +C R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C+K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G+  S     K++G
Sbjct:  253 ETNCHWEGCSKEYDTQEQLVHHINNEHIHGE-KKEFVCRWDECSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDLPSRPHPPKENG 431
[Close]
BLAST of GLI-1 vs. Ensembl Zebrafish
Match: gli2a (GLI family zinc finger 2a [Source:ZFIN;Acc:ZDB-GENE-990706-8])

HSP 1 Score: 279.641 bits (714), Expect = 1.804e-77
Identity = 123/169 (72.78%), Postives = 139/169 (82.25%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGES 1837
            ETNCHW  C K +DTQ +LV HIS  HI G  K+ FVC+W +C R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C+K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G++
Sbjct:  401 ETNCHWEGCAKEYDTQDQLVHHISNDHIHGE-KKEFVCRWVECSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDA 568
[Close]
BLAST of GLI-1 vs. Ensembl Zebrafish
Match: gli2a (GLI family zinc finger 2a [Source:ZFIN;Acc:ZDB-GENE-990706-8])

HSP 1 Score: 279.256 bits (713), Expect = 2.018e-77
Identity = 123/169 (72.78%), Postives = 139/169 (82.25%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGES 1837
            ETNCHW  C K +DTQ +LV HIS  HI G  K+ FVC+W +C R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C+K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G++
Sbjct:  405 ETNCHWEGCAKEYDTQDQLVHHISNDHIHGE-KKEFVCRWVECSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDA 572
[Close]
BLAST of GLI-1 vs. Ensembl Xenopus
Match: GLI1 (GLI family zinc finger 1 [Source:NCBI gene;Acc:100494064])

HSP 1 Score: 289.656 bits (740), Expect = 4.531e-81
Identity = 135/198 (68.18%), Postives = 151/198 (76.26%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDGYSSGKYNWDHQLSMKNSS 1924
            ETNCHW  C K FDTQ  LV HI+  HI G  K+ FVC W+DC R  RPFKAQYMLVVHMRRHTGEKPH+CTF  CNK YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G+    R QS  +G  +     ++QL M+ SS
Sbjct:  153 ETNCHWESCTKEFDTQEHLVHHINNEHIHGE-KKEFVCHWQDCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCNKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHITKKHRGDGMP-RTQSGHEGSGNHTVKGENQLDMEASS 348
[Close]
BLAST of GLI-1 vs. Ensembl Xenopus
Match: GLI1 (GLI family zinc finger 1 [Source:NCBI gene;Acc:100494064])

HSP 1 Score: 289.656 bits (740), Expect = 8.456e-81
Identity = 135/198 (68.18%), Postives = 151/198 (76.26%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDGYSSGKYNWDHQLSMKNSS 1924
            ETNCHW  C K FDTQ  LV HI+  HI G  K+ FVC W+DC R  RPFKAQYMLVVHMRRHTGEKPH+CTF  CNK YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G+    R QS  +G  +     ++QL M+ SS
Sbjct:  249 ETNCHWESCTKEFDTQEHLVHHINNEHIHGE-KKEFVCHWQDCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCNKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHITKKHRGDGMP-RTQSGHEGSGNHTVKGENQLDMEASS 444
[Close]
BLAST of GLI-1 vs. Ensembl Xenopus
Match: cep164 (centrosomal protein 164kDa [Source:Xenbase;Acc:XB-GENE-6035710])

HSP 1 Score: 280.411 bits (716), Expect = 1.828e-77
Identity = 127/184 (69.02%), Postives = 143/184 (77.72%), Query Frame = 2 
Query: 1307 QEGDPD--------FTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGE 1834
            +EGD D          ETNCHW  C + FDTQ +LV HI+  HI G  K+ FVC+W DC R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C+K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G+
Sbjct:  467 EEGDKDESKQEPEVVYETNCHWEGCSREFDTQEQLVHHINNDHIHGEKKE-FVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGD 649
[Close]
BLAST of GLI-1 vs. Ensembl Xenopus
Match: shmt1 (serine hydroxymethyltransferase 1 (soluble) [Source:Xenbase;Acc:XB-GENE-966676])

HSP 1 Score: 276.174 bits (705), Expect = 2.576e-76
Identity = 132/227 (58.15%), Postives = 157/227 (69.16%), Query Frame = 2 
Query: 1193 KSFRYDISNEKQEHFQLSNVDKLIEKHSDNSYKLCSKPQEGDPDFT-ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDG 1870
            K  +  + +E  +    S  D L +   D     C +    +PD   ETNCHW+ C   FDTQ +LV HI+  HI G  K+ FVC+W DC R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPY+CK+ GC KRYTDPSSLRKHVKT HGP+ +  KK + +       +K++G
Sbjct:  243 KRSKVKMEDEGLQRDSPSPPDHLTDLKEDLDKDECKQ----EPDVIYETNCHWDGCSHEFDTQDQLVHHINNDHIHGE-KKEFVCRWHDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCYKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKHRNDIIQKPSVTKENG 464
[Close]
BLAST of GLI-1 vs. Ensembl Xenopus
Match: shmt1 (serine hydroxymethyltransferase 1 (soluble) [Source:Xenbase;Acc:XB-GENE-966676])

HSP 1 Score: 275.789 bits (704), Expect = 3.846e-76
Identity = 132/227 (58.15%), Postives = 157/227 (69.16%), Query Frame = 2 
Query: 1193 KSFRYDISNEKQEHFQLSNVDKLIEKHSDNSYKLCSKPQEGDPDFT-ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDG 1870
            K  +  + +E  +    S  D L +   D     C +    +PD   ETNCHW+ C   FDTQ +LV HI+  HI G  K+ FVC+W DC R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPY+CK+ GC KRYTDPSSLRKHVKT HGP+ +  KK + +       +K++G
Sbjct:  295 KRSKVKMEDEGLQRDSPSPPDHLTDLKEDLDKDECKQ----EPDVIYETNCHWDGCSHEFDTQDQLVHHINNDHIHGE-KKEFVCRWHDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCYKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKHRNDIIQKPSVTKENG 516
[Close]
BLAST of GLI-1 vs. Ensembl Mouse
Match: Gli3 (GLI-Kruppel family member GLI3 [Source:MGI Symbol;Acc:MGI:95729])

HSP 1 Score: 280.026 bits (715), Expect = 1.986e-77
Identity = 123/168 (73.21%), Postives = 137/168 (81.55%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGE 1834
            ETNCHW  C + FDTQ +LV HI+  HI G  K+ FVC+W DC R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G+
Sbjct:  479 ETNCHWEGCTREFDTQDQLVHHINNDHIHGE-KKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGD 645
[Close]
BLAST of GLI-1 vs. Ensembl Mouse
Match: Gli2 (GLI-Kruppel family member GLI2 [Source:MGI Symbol;Acc:MGI:95728])

HSP 1 Score: 278.485 bits (711), Expect = 6.389e-77
Identity = 123/174 (70.69%), Postives = 139/174 (79.89%), Query Frame = 2 
Query: 1307 QEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMK 1828
            QE +    ETNCHW DC K +DTQ +LV HI+  HI G  K+ FVC+W+ C R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C+K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPY+CK+ GC KRYTDPSSLRKHVKT HGP  +  KK +
Sbjct:  408 QEAEVVIYETNCHWADCTKEYDTQEQLVHHINNEHIHGE-KKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQR 580
[Close]
BLAST of GLI-1 vs. Ensembl Mouse
Match: Gli1 (GLI-Kruppel family member GLI1 [Source:MGI Symbol;Acc:MGI:95727])

HSP 1 Score: 266.929 bits (681), Expect = 5.865e-74
Identity = 121/175 (69.14%), Postives = 136/175 (77.71%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQ 1855
            ET+C W+ C + FD+Q +LV HI++ HI G  K+ FVC W  C R  RPFKAQYMLVVHMRRHTGEKPH+CTF  C K YSRLENLKTH+RSHTGEKPY CE  GC KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP  +  K+ +G+    R Q
Sbjct:  237 ETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKE-FVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEQEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAQ 410
[Close]
BLAST of GLI-1 vs. Ensembl Mouse
Match: Glis3 (GLIS family zinc finger 3 [Source:MGI Symbol;Acc:MGI:2444289])

HSP 1 Score: 217.238 bits (552), Expect = 2.875e-59
Identity = 96/162 (59.26%), Postives = 117/162 (72.22%), Query Frame = 2 
Query: 1340 CHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKM 1825
            C W DC   +D Q ELV+HI  +HI     + F C W  C R  +PF A+Y L++HMR H+GEKP++CTF  C K +SRLENLK H+RSHTGEKPY C+ PGC KAFSN+SDRAKHQ RTH +TKPY C++ GC KRYTDPSSLRKHVK +   +  A KK+
Sbjct:  502 CRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWTGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCKKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQ-RTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSREQQARKKL 662
[Close]
BLAST of GLI-1 vs. Ensembl Mouse
Match: Glis3 (GLIS family zinc finger 3 [Source:MGI Symbol;Acc:MGI:2444289])

HSP 1 Score: 218.779 bits (556), Expect = 2.027e-58
Identity = 96/163 (58.90%), Postives = 118/163 (72.39%), Query Frame = 2 
Query: 1340 CHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMK 1828
            C W DC   +D Q ELV+HI  +HI     + F C W  C R  +PF A+Y L++HMR H+GEKP++CTF  C K +SRLENLK H+RSHTGEKPY C+ PGC KAFSN+SDRAKHQ RTH +TKPY C++ GC KRYTDPSSLRKHVK +   +  A KK++
Sbjct:  502 CRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWTGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCKKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQ-RTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSREQQARKKLR 663
[Close]
BLAST of GLI-1 vs. UniProt/SwissProt
Match: sp|P19538|CI_DROME (Transcriptional activator cubitus interruptus OS=Drosophila melanogaster OX=7227 GN=ci PE=1 SV=2)

HSP 1 Score: 287.73 bits (735), Expect = 2.579e-79
Identity = 146/251 (58.17%), Postives = 175/251 (69.72%), Query Frame = 2 
Query: 1322 DFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSD---RCQSKQDGYSSGKYNWDHQLSMKNSS-ENFIGTHSNSLHTPSSSTQTTNAW------SDNL---SPNDVAFNI 2035
            DF ETNCHW  C   F TQ ELVKHI+  HI  + K+ FVC+W+DC R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C K YSRLENLKTH+RSHTGEKPY CE+PGC KAFSNASDRAKHQNRTHSN KPY+CK  GC KRYTDPSSLRKHVKT HG + YA+KK KG   +D   R Q     ++  ++N D     ++S     +GT S S+ + S  + + +        SD+L   SP+D+A N+
Sbjct:  447 DFIETNCHWRSCRIEFITQDELVKHINNDHIQ-TNKKAFVCRWEDCTRGEKPFKAQYMLVVHMRRHTGEKPHKCTFEGCFKAYSRLENLKTHLRSHTGEKPYTCEYPGCSKAFSNASDRAKHQNRTHSNEKPYICKAPGCTKRYTDPSSLRKHVKTVHGAEFYANKKHKGLPLNDANSRLQQNNSRHNLQEHNIDSSPCSEDSHLGKMLGTSSPSIKSESDISSSNHHLVNGVRASDSLLTYSPDDLAENL 696
[Close]
BLAST of GLI-1 vs. UniProt/SwissProt
Match: sp|Q91690|GLI1_XENLA (Zinc finger protein GLI1 (Fragment) OS=Xenopus laevis OX=8355 GN=gli1 PE=2 SV=2)

HSP 1 Score: 287.345 bits (734), Expect = 2.781e-79
Identity = 134/198 (67.68%), Postives = 150/198 (75.76%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDGYSSGKYNWDHQLSMKNSS 1924
            ETNCHW  C K FDTQ  LV HI+  HI G  K+ FVC W+DC R  RPFKAQYMLVVHMRRHTGEKPH+CTF  CNK YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G+    R Q   +G  +     ++QL M+ SS
Sbjct:  249 ETNCHWESCTKEFDTQEHLVHHINNEHIHGE-KKEFVCHWQDCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCNKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHITKKHRGDGML-RAQPGHEGPGNQNVKGENQLDMEASS 444
[Close]
BLAST of GLI-1 vs. UniProt/SwissProt
Match: sp|P55878|GLI1_CHICK (Zinc finger protein GLI1 (Fragment) OS=Gallus gallus OX=9031 GN=GLI1 PE=2 SV=1)

HSP 1 Score: 272.707 bits (696), Expect = 4.360e-79
Identity = 125/178 (70.22%), Postives = 140/178 (78.65%), Query Frame = 2 
Query: 1307 QEGDPD---FTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKG 1831
            ++G P+     ETNC+W+ C K FDTQ +LV HI+  HI G  K+ FVC W  C R  RPFKAQYMLVVHMRRHTGEKPH+CTF  CNK YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPY+CK+ GC KRYTDPSSLRKHVKT HGP  +  KK +G
Sbjct:  235 EDGKPESETIYETNCYWDGCAKEFDTQEQLVHHINNEHIHGE-KKEFVCHWAACSREQRPFKAQYMLVVHMRRHTGEKPHKCTFEGCNKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKHRG 411
[Close]
BLAST of GLI-1 vs. UniProt/SwissProt
Match: sp|P55879|GLI2_CHICK (Zinc finger protein GLI2 (Fragment) OS=Gallus gallus OX=9031 GN=GLI2 PE=2 SV=1)

HSP 1 Score: 275.404 bits (703), Expect = 5.380e-79
Identity = 122/166 (73.49%), Postives = 136/166 (81.93%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMK 1828
            ETNCHW  C K +DTQ +LV HI+  HI G  K+ FVC+W+DC R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C+K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP  +  KK +
Sbjct:  233 ETNCHWEGCTKEYDTQEQLVHHINNDHIHGEKKE-FVCRWQDCTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQR 397
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BLAST of GLI-1 vs. UniProt/SwissProt
Match: sp|Q9IA31|GLI3_CHICK (Transcriptional activator GLI3 (Fragment) OS=Gallus gallus OX=9031 GN=GLI3 PE=1 SV=1)

HSP 1 Score: 280.796 bits (717), Expect = 7.593e-77
Identity = 127/184 (69.02%), Postives = 142/184 (77.17%), Query Frame = 2 
Query: 1307 QEGDPD--------FTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGE 1834
            +EGD D          ETNCHW  C + FDTQ +LV HI+  HI G  K+ FVC+W DC R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G+
Sbjct:  465 EEGDKDESKQEPEVVYETNCHWEGCSREFDTQEQLVHHINNDHIHGE-KKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGD 647
[Close]
BLAST of GLI-1 vs. TrEMBL
Match: D2ILS3 (GLI-1 OS=Schmidtea mediterranea OX=79327 GN=gli-1 PE=2 SV=1)

HSP 1 Score: 1694.86 bits (4388), Expect = 0.000e+0
Identity = 876/880 (99.55%), Postives = 877/880 (99.66%), Query Frame = 2 
Query:  368 MTSFSNKTRLGKNCRNGKDSRNMNFWNSENSCNINANDCNIPADGNINSANVNYNQNLPCFINQPSCDQWPFVSNFNCFQHQYLVPNHFPYFQNGCVTQNNIPLNYCKATNNEIKHISGENINQCLSNNHLPYVVMNYLSGNATPANELVPNPGSLFNNLNNSSADNSHDSQPMDVGFHLPNSTSFRAGCQSDNHYNSNFRSLLGSKRPRTQASLSDFIDIQTLTRVSQDSLAVRSLXXXXXXXXXXXXXXXXXXXXMGSPPGINQYTFPQSGDTKSFRYDISNEKQEHFQLSNVDKLIEKHSDNSYKLCSKPQEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDGYSSGKYNWDHQLSMKNSSENFIGTHSNSLHTPSSSTQTTNAWSDNLSPNDVAFNILTNLSNNDSXXXXXXXXXXXXXXXXXMNGSNVVAVRTNPTNQAMPNKMRMKTEFITNTNKLTTEMINKFEEDSKFNEMSSVIGALXXXXXXXXXXXXXXXAVNINGEKAQSHFNNSSLSETAAVKLEHYFSHSQNPSIAFEPSKSQLSSFYNHPYNSPSMNSVNNSFGIINCQTPTNIIQDHTPVYFNPRSPYTHQHHVYYNTQHQINGFNSVSCSPCHVYHCNPYYGSTGVPSSTNNQCCCHNAGLVTNGFGDSRLTQSLCSSLSTGSCNLHSTCNYHPSNDRYSNILDENIVSVSMDQLPLLETLSDNLVVCQNKMPFNKNI 3007
            MTSFSNKTRLGKNCRNGKDSRNMNFWNSENSCNINANDCNIPADGNINSANVNYNQNLPCFINQPSCDQWPFVSNFNCFQHQYLVPNHFPYFQNGCVTQNNIPLNYCKATNNEIKHISGENINQCLSNNHLPYVVMNYLSGNATPANELVPNPGSLFNNLNNSSADNSHDSQPMDVGFHLPNSTSFRAGCQSDNHYNSNFRSLLGSKRPRTQASLSDFIDIQTLTRVSQDSLAVRSLHSRSGAGSSIGSIGHLSAASMGSPPGINQYTFPQSGDTKSFRYDISNEKQEHFQ SNVDKLIEKHSDNSYKLCSKPQEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHT EKPHQCTFPNCNKRYSRLE+LKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVE CAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDGYSSGKYNWDHQLSMKNSSENFIGTHSNSLHTPSSSTQTTNAWSDNLSPNDVAFNILTNLSNNDSLIFDADDEDILEIDTLDMNGSNVVAVRTNPTNQAMPNKMRMKTEFITNTNKLTTEMINKFEEDSKFNEMSSVIGALSEVSSGIGSLSSTKSAVNINGEKAQSHFNNSSLSETAAVKLEHYFSHSQNPSIAFEPSKSQLSSFYNHPYNSPSMNSVNNSFGIINCQTPTNIIQDHTPVYFNPRSPYTHQHHVYYNTQHQINGFNSVSCSPCHVYHCNPYYGSTGVPSSTNNQCCCHNAGLVTNGFGDSRLTQSLCSSLSTGSCNLHSTCNYHPSNDRYSNILDENIVSVSMDQLPLLETLSDNLVVCQNKMPFNKNI
Sbjct:    1 MTSFSNKTRLGKNCRNGKDSRNMNFWNSENSCNINANDCNIPADGNINSANVNYNQNLPCFINQPSCDQWPFVSNFNCFQHQYLVPNHFPYFQNGCVTQNNIPLNYCKATNNEIKHISGENINQCLSNNHLPYVVMNYLSGNATPANELVPNPGSLFNNLNNSSADNSHDSQPMDVGFHLPNSTSFRAGCQSDNHYNSNFRSLLGSKRPRTQASLSDFIDIQTLTRVSQDSLAVRSLHSRSGAGSSIGSIGHLSAASMGSPPGINQYTFPQSGDTKSFRYDISNEKQEHFQPSNVDKLIEKHSDNSYKLCSKPQEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTSEKPHQCTFPNCNKRYSRLESLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVERCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDGYSSGKYNWDHQLSMKNSSENFIGTHSNSLHTPSSSTQTTNAWSDNLSPNDVAFNILTNLSNNDSLIFDADDEDILEIDTLDMNGSNVVAVRTNPTNQAMPNKMRMKTEFITNTNKLTTEMINKFEEDSKFNEMSSVIGALSEVSSGIGSLSSTKSAVNINGEKAQSHFNNSSLSETAAVKLEHYFSHSQNPSIAFEPSKSQLSSFYNHPYNSPSMNSVNNSFGIINCQTPTNIIQDHTPVYFNPRSPYTHQHHVYYNTQHQINGFNSVSCSPCHVYHCNPYYGSTGVPSSTNNQCCCHNAGLVTNGFGDSRLTQSLCSSLSTGSCNLHSTCNYHPSNDRYSNILDENIVSVSMDQLPLLETLSDNLVVCQNKMPFNKNI 880
[Close]
BLAST of GLI-1 vs. TrEMBL
Match: D0VYP4 (GLI family zinc finger protein OS=Dugesia japonica OX=6161 GN=Djgli PE=2 SV=1)

HSP 1 Score: 1310.82 bits (3391), Expect = 0.000e+0
Identity = 715/893 (80.07%), Postives = 783/893 (87.68%), Query Frame = 2 
Query:  368 MTSFSNKTRLGKNCRNGKDSRNMNFWNSENSCNIN-------ANDCNIPADGNINSANVNYNQNLPCFINQPSCDQWPFVSNFNCFQHQYLVPNHFPYFQNGCVTQNNIPLNYCKATNNEIKHISGEN-INQCLSNNHLPYVVM-NYLSGNATPANELVPNPGSLFNNLNNSSADNSHDSQPMDVG-FHLPNSTSFRAGCQSDNHYNSNFRSLLGSKRPRTQASLSDFIDIQTLTRVSQDSLAVRSLXXXXXXXXXXXXXXXXXXXXMGSPPGINQYTFPQSGDTKSFRYDISNEKQEHFQLSNVDKLIEKHSDNSYKLCSKPQEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDGYSSGKYNWDHQLSMKNSSENFIGTHSNSLHTPSSSTQTTNAWSDNLSPNDVAFNILTNLSNNDSXXXXXXXXXXXXXXXXXMNGSNVVAVRTNPTNQAMPNKMRMKTEFITNTNKLTTEMINKFEEDSKFNEMSSVIGALXXXXXXXXXXXXXXXAVNINGEKAQSHFNN---SSLSETAAVKLEHYFSHSQNPSIAFEPSKSQLSSFYNHPYNSPSMNSVNNSFGIINCQTPTNIIQDHTPVYFNPRSPYTHQHHVYYNTQHQINGFNSVSCSPCHVYHCNPYYGSTGVPSSTNNQCCCHNAGLVTNGFGDSRLTQSLCSSLSTGSCNLHS--TCNYHPSNDRYSNILDENIVSVSMDQLPLLETLSDNLVVCQNKMPFNK 3001
            MTSF+NKTRLGKNCR GK+SRN NFWN ENS NIN         + NIP D NI++ NVNYNQNLPCFIN  SCDQ PFV+NFNCFQHQYLVPNHF YFQ GCVTQNNIPLNYC A  NEIK  S +N +NQCLSNNHLPYVVM NYLSGN+TPAN+ +P+ GS+FNN+ NS+ D +H++Q  D+  FHLP STSFR+GC SDN +N NFRS++GSKRPRTQASLSDFIDIQTLTRVSQDSLAVRSLHSRSGAGSS+GSIGHLSAASMGSPPGINQYTFPQ+ +TK FR +  ++K E+ Q SNV+K IEK+S NSYK+ SKPQEGDPDFTETNCHWNDC K FDTQ+ELVKHISTIHISGSGKQTF+CQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQ GYS+GK NWDHQLS+KN SEN+ GT+SNSLHTPSSST TTNAWSDNLSPNDVAFNILTNLSNNDSL FDADDEDIL +D L+M+GSNV+A+R+N +N ++ NKM MKTEFIT+ N LTTEMINKFEEDSKFNE+SSVIGALSEVSSGIGSLSS KSAVN+NGEK   H NN   +SLSETAAVKLEHYFSHSQNP +AFE SKSQLSSFYNH YN P MNS NNSF IINCQTPTNIIQD+TPVYF P + Y HQ H+Y NTQHQ +GFN+VSC PCH+YHCN YYG+T   SS NNQCCCH +GL+ +GF DSR TQSLCSSLSTGS N HS  +CNY+ S D YSNILDENIVSVSMDQLPL+ETLSDNLVVCQNK+ F+K
Sbjct:    1 MTSFNNKTRLGKNCRIGKESRNDNFWNPENSNNININNSNNNTTEYNIPTDINIHNTNVNYNQNLPCFINPQSCDQLPFVTNFNCFQHQYLVPNHFSYFQKGCVTQNNIPLNYCMA-GNEIKPFSADNSVNQCLSNNHLPYVVMKNYLSGNSTPANDFMPSSGSIFNNIVNSNVD-THNTQQTDMSSFHLPYSTSFRSGCHSDNRFNGNFRSVMGSKRPRTQASLSDFIDIQTLTRVSQDSLAVRSLHSRSGAGSSMGSIGHLSAASMGSPPGINQYTFPQTSETKLFRCENLHDKSENIQFSNVEKSIEKYSANSYKIYSKPQEGDPDFTETNCHWNDCAKMFDTQSELVKHISTIHISGSGKQTFICQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQVGYSTGKCNWDHQLSLKN-SENYNGTNSNSLHTPSSSTHTTNAWSDNLSPNDVAFNILTNLSNNDSLTFDADDEDILALDGLEMSGSNVLAIRSNSSNPSIMNKMHMKTEFITDNNGLTTEMINKFEEDSKFNEISSVIGALSEVSSGIGSLSSAKSAVNLNGEKTPFHSNNVNYTSLSETAAVKLEHYFSHSQNPPMAFETSKSQLSSFYNHSYNPPCMNSGNNSFNIINCQTPTNIIQDNTPVYFGPNNSYPHQ-HMYCNTQHQFSGFNTVSCPPCHIYHCNSYYGATRNSSSANNQCCCHRSGLIASGFSDSRQTQSLCSSLSTGSYNPHSHPSCNYNISTDTYSNILDENIVSVSMDQLPLMETLSDNLVVCQNKVTFSK 889
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BLAST of GLI-1 vs. TrEMBL
Match: A0A0X3PQV5 (Uncharacterized protein (Fragment) OS=Schistocephalus solidus OX=70667 GN=TR124045 PE=4 SV=1)

HSP 1 Score: 317.39 bits (812), Expect = 4.121e-93
Identity = 141/182 (77.47%), Postives = 158/182 (86.81%), Query Frame = 2 
Query: 1304 PQEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDR 1849
            PQEGDPDF ET C W  C   FD+Q ELVKHIS  HI+G+ K++FVC W++CVR  RPFKAQYMLVVHMRRHTGEKPH+C F  C+KRYSRLENLKTH+RSHTGEKPY+CE PGC+KAFSNASDRAKHQNRTHSN KPY+CKV GC+KRYTDPSSLRKHVKT HG +VYA+KK KGESWS+R
Sbjct:  325 PQEGDPDFVETTCRWGTCQCQFDSQDELVKHISNEHIAGN-KKSFVCFWRECVRGARPFKAQYMLVVHMRRHTGEKPHKCIFEGCSKRYSRLENLKTHLRSHTGEKPYQCEVPGCNKAFSNASDRAKHQNRTHSNEKPYICKVAGCSKRYTDPSSLRKHVKTVHGAEVYANKKHKGESWSNR 505
[Close]
BLAST of GLI-1 vs. TrEMBL
Match: A0A4Z2D0L8 (Transcriptional activator protein OS=Schistosoma japonicum OX=6182 GN=EWB00_005796 PE=4 SV=1)

HSP 1 Score: 329.717 bits (844), Expect = 1.899e-90
Identity = 146/193 (75.65%), Postives = 162/193 (83.94%), Query Frame = 2 
Query: 1304 PQEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDGYSSG 1882
            PQEGDPDF ET C W DC + FD Q ELVKH+ST HI+G  K++F+C W++CVR  RPFKAQYMLVVHMRRHTGEKPH+C F  C KRYSRLENLKTH+RSHTGEKPY+CE PGC+KAFSNASDRAKHQNRTHSN KPY CKV+GC+KRYTDPSSLRKHVKT HG +VYA+KK KGESWSDR      GYS G
Sbjct: 1025 PQEGDPDFVETTCRWGDCTQQFDDQDELVKHLSTEHIAG-NKKSFICLWRECVRGTRPFKAQYMLVVHMRRHTGEKPHKCIFEGCTKRYSRLENLKTHLRSHTGEKPYQCEIPGCNKAFSNASDRAKHQNRTHSNEKPYTCKVDGCSKRYTDPSSLRKHVKTVHGAEVYANKKHKGESWSDR-PCGGSGYSGG 1215
[Close]
BLAST of GLI-1 vs. TrEMBL
Match: A0A430QLR6 (Transcriptional activator cubitus interruptus OS=Schistosoma bovis OX=6184 GN=DC041_0009388 PE=4 SV=1)

HSP 1 Score: 327.791 bits (839), Expect = 1.014e-89
Identity = 143/182 (78.57%), Postives = 157/182 (86.26%), Query Frame = 2 
Query: 1304 PQEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDR 1849
            PQEGDPDF ET C W DC   FD Q ELVKH+ST HI+G  K++FVC W++CVR  RPFKAQYMLVVHMRRHTGEKPH+C F  C KRYSRLENLKTH+RSHTGEKPY+CE PGC+KAFSNASDRAKHQNRTHSN KPY CKV+GC+KRYTDPSSLRKHVKT HG +VYA+KK KGESWSDR
Sbjct: 1031 PQEGDPDFVETTCRWGDCTLQFDDQDELVKHLSTEHIAG-NKKSFVCLWRECVRGTRPFKAQYMLVVHMRRHTGEKPHKCIFEGCTKRYSRLENLKTHLRSHTGEKPYQCEIPGCNKAFSNASDRAKHQNRTHSNEKPYTCKVDGCSKRYTDPSSLRKHVKTVHGAEVYANKKHKGESWSDR 1211
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BLAST of GLI-1 vs. Ensembl Cavefish
Match: gli1 (GLI family zinc finger 1 [Source:ZFIN;Acc:ZDB-GENE-030321-1])

HSP 1 Score: 283.878 bits (725), Expect = 5.752e-79
Identity = 127/169 (75.15%), Postives = 139/169 (82.25%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGES 1837
            ETNCHW  C K FDTQ +LV HI+  HI G  K+ FVC WKDC R  RPFKAQYMLVVHMRRHTGEKPH+CTF  CNK YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G++
Sbjct:  322 ETNCHWESCSKEFDTQEQLVHHINNEHIHGE-KKEFVCHWKDCSREQRPFKAQYMLVVHMRRHTGEKPHKCTFEGCNKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHITKKHRGDT 489
[Close]
BLAST of GLI-1 vs. Ensembl Cavefish
Match: gli3 (GLI family zinc finger 3 [Source:ZFIN;Acc:ZDB-GENE-041111-162])

HSP 1 Score: 278.87 bits (712), Expect = 2.794e-77
Identity = 126/194 (64.95%), Postives = 150/194 (77.32%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDGYSSGKYNWDHQLSM 1912
            ETNCHW +C + FDTQ +LV HI+  HI G  K+ FVC+W++C R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C+K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G+ +       ++  S+G+     QL +
Sbjct:  457 ETNCHWENCCREFDTQEQLVHHINNDHIHGE-KKEFVCRWEECSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDVYPRPPPQPREPGSNGQGRSPGQLPL 649
[Close]
BLAST of GLI-1 vs. Ensembl Cavefish
Match: gli2a (GLI family zinc finger 2 [Source:NCBI gene;Acc:103029390])

HSP 1 Score: 278.87 bits (712), Expect = 2.865e-77
Identity = 125/182 (68.68%), Postives = 144/182 (79.12%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDGYS 1876
            ETNCHW  C K +DTQ +LV HI+  HI G  K+ FVC+W +C R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C+K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G++ +     K +G S
Sbjct:  394 ETNCHWEGCSKEYDTQEQLVHHINNDHIHGE-KKEFVCRWDECSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDAPTKPHPPKGNGES 574
[Close]
BLAST of GLI-1 vs. Ensembl Cavefish
Match: gli2b (zinc finger protein GLI2-like [Source:NCBI gene;Acc:103028990])

HSP 1 Score: 277.715 bits (709), Expect = 7.942e-77
Identity = 122/168 (72.62%), Postives = 139/168 (82.74%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGE 1834
            ETNCHW  C K +DTQ +LV HI+  HI G  K+ FVC+W++C R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C+K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G+
Sbjct:  402 ETNCHWEGCSKEYDTQEQLVHHINNEHIHGE-KKEFVCRWEECSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGD 568
[Close]
BLAST of GLI-1 vs. Ensembl Cavefish
Match: glis3 (GLIS family zinc finger 3 [Source:ZFIN;Acc:ZDB-GENE-070112-2232])

HSP 1 Score: 218.394 bits (555), Expect = 5.807e-61
Identity = 102/186 (54.84%), Postives = 131/186 (70.43%), Query Frame = 2 
Query: 1322 DFTETNC-HWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDGYS 1876
            DF+E +C  W DC  T+  + ELVKHI  +H+     + F C W  C R  +PF A+Y L++HMR H+GEKP++CTF  C K +SRLENLK H+RSHTGEKPY C+ PGC KAFSN+SDRAKHQ RTH +TKPY C+++GC KRYTDPSSLRKHVK++   +  A KK++  +     +  QDG S
Sbjct:  299 DFSEGHCCRWLDCNATYSHKEELVKHIEKLHMDQRKGEDFTCYWAGCPRRHKPFNARYKLLIHMRVHSGEKPNKCTFEGCQKAFSRLENLKIHLRSHTGEKPYTCQHPGCQKAFSNSSDRAKHQ-RTHIDTKPYACQIQGCLKRYTDPSSLRKHVKSHSTKEQQARKKLRSST-----EFNQDGLS 478
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BLAST of GLI-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008614.1 (pep scaffold:Pmarinus_7.0:GL479003:10005:19084:-1 gene:ENSPMAG00000007806.1 transcript:ENSPMAT00000008614.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 221.861 bits (564), Expect = 7.027e-68
Identity = 103/131 (78.63%), Postives = 112/131 (85.50%), Query Frame = 2 
Query: 1394 HISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVK 1786
            HI+  HI G  K+ FVC+W+DC R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVK
Sbjct:    1 HINNEHIHGERKE-FVCRWRDCSREKKPFKAQYMLVVHMRRHTGEKPHKCTFEGCAKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKISGCTKRYTDPSSLRKHVK 130
[Close]
BLAST of GLI-1 vs. Ensembl Sea Lamprey
Match: glis2b (GLIS family zinc finger 2b [Source:ZFIN;Acc:ZDB-GENE-091204-120])

HSP 1 Score: 180.644 bits (457), Expect = 2.420e-52
Identity = 87/152 (57.24%), Postives = 105/152 (69.08%), Query Frame = 2 
Query: 1355 CVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTN---HGP 1801
            C + FD+Q ELV+H+   H+    +  + C W+ C R GR F A+Y +++H+R HT EKPHQC  P CNK +SRLENLK H RSHTGEKPY C + GC K +SN+SDR KH  RTH   KPY CK  GC KRYTDPSSLRKHVK +   HGP
Sbjct:    3 CQQVFDSQQELVEHVHDAHVRADREVGYCCHWEGCARMGRGFNARYKMLIHVRTHTNEKPHQC--PICNKSFSRLENLKIHGRSHTGEKPYACPYQGCSKRYSNSSDRFKH-TRTHYVDKPYACKTPGCLKRYTDPSSLRKHVKAHGHQHGP 151
[Close]
BLAST of GLI-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003448.1 (pep scaffold:Pmarinus_7.0:GL477543:42863:56609:1 gene:ENSPMAG00000003158.1 transcript:ENSPMAT00000003448.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 153.68 bits (387), Expect = 2.337e-43
Identity = 78/155 (50.32%), Postives = 99/155 (63.87%), Query Frame = 2 
Query: 1328 TETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFS--NASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVK 1786
            T   C W +C   F  + +L +HI   H+     + F CQW+ C R  RPF A+Y L++HMR H+GEKP++C    C + +S  +  K   R H   K  +C F GC KAFS  N+SDRAKHQ RTH +TKPYVC+V GC+KRYTDPSSLRKHVK
Sbjct:    4 TGEACRWEECRAAFGRREQLCRHIEKSHVEPQRGEEFACQWEACGRRRRPFNARYKLLIHMRVHSGEKPNRCML--CCETFSHSDTHKHSTRPHQDIKRLQCTFEGCPKAFSRLNSSDRAKHQ-RTHQDTKPYVCQVPGCSKRYTDPSSLRKHVK 155
[Close]
BLAST of GLI-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003451.1 (pep scaffold:Pmarinus_7.0:GL477543:42884:56609:1 gene:ENSPMAG00000003158.1 transcript:ENSPMAT00000003451.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 150.599 bits (379), Expect = 2.416e-42
Identity = 77/152 (50.66%), Postives = 99/152 (65.13%), Query Frame = 2 
Query: 1340 CHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECE-FPGCHKAFS--NASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVK 1786
            C W +C   F  + +L +HI   H+     + F CQW+ C R  RPF A+Y L++HMR H+GEKP++C     +K +  L N +T  +S T  +   C  F GC KAFS  N+SDRAKHQ RTH +TKPYVC+V GC+KRYTDPSSLRKHVK
Sbjct:    1 CRWEECRAAFGRREQLCRHIEKSHVEPQRGEEFACQWEACGRRRRPFNARYKLLIHMRVHSGEKPNRCMVSGGSKYHLDLPNWRTRRKSITPSRSAVCRHFEGCPKAFSRLNSSDRAKHQ-RTHQDTKPYVCQVPGCSKRYTDPSSLRKHVK 151
[Close]
BLAST of GLI-1 vs. Ensembl Sea Lamprey
Match: znf143b (zinc finger protein 143b [Source:NCBI gene;Acc:393954])

HSP 1 Score: 117.087 bits (292), Expect = 2.397e-28
Identity = 65/156 (41.67%), Postives = 84/156 (53.85%), Query Frame = 2 
Query: 1340 CHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQV 1807
            C    C K F T  +L KHI T     +G++ F C ++ C   GR F    +  VH+R HTGE+P+ C  P C + +S   N K H+R HTGEKPY C  PGC K F+  S   KHQ   H+  KPY C    C+K Y  PS+L  H ++ HG  V
Sbjct:  197 CPDETCRKGFKTSGDLQKHIRTH----TGEKPFKCPFEGC---GRSFTTSNIRKVHIRTHTGERPYLCPEPGCGRGFSSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKHQV-VHTPVKPYSCS--NCSKTYRQPSTLATHKRSAHGGDV 342

HSP 2 Score: 102.834 bits (255), Expect = 1.359e-23
Identity = 51/159 (32.08%), Postives = 86/159 (54.09%), Query Frame = 2 
Query: 1337 NCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYA 1813
            +C +  C + + T      H+     + +G + + C    C   G+ F   Y L  H+R HTGEKP+ C    C K +    +L+ HIR+HTGEKP++C F GC ++F+ ++ R  H  RTH+  +PY+C   GC + ++  ++ + HV+ + G + Y 
Sbjct:  136 HCRYEGCGRLYTT----AHHLKVHERAHTGDRPYRCNQPCC---GKAFSTGYGLKSHLRTHTGEKPYLCPDETCRKGFKTSGDLQKHIRTHTGEKPFKCPFEGCGRSFTTSNIRKVH-IRTHTGERPYLCPEPGCGRGFSSATNYKNHVRIHTGEKPYV 286

HSP 3 Score: 80.4925 bits (197), Expect = 3.099e-16
Identity = 38/93 (40.86%), Postives = 53/93 (56.99%), Query Frame = 2 
Query: 1520 TGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHG 1798
            +GEK   C +  C + Y+   +LK H R+HTG++PY C  P C KAFS       H  RTH+  KPY+C  E C K +     L+KH++T+ G
Sbjct:  130 SGEKAFHCRYEGCGRLYTTAHHLKVHERAHTGDRPYRCNQPCCGKAFSTGYGLKSHL-RTHTGEKPYLCPDETCRKGFKTSGDLQKHIRTHTG 221
[Close]
BLAST of GLI-1 vs. Ensembl Yeast
Match: ZAP1 (Zinc-regulated transcription factor; binds to zinc-responsive promoters to induce transcription of certain genes in presence of zinc, represses other genes in low zinc; regulates its own transcription; contains seven zinc-finger domains [Source:SGD;Acc:S000003592])

HSP 1 Score: 107.842 bits (268), Expect = 2.928e-24
Identity = 65/187 (34.76%), Postives = 96/187 (51.34%), Query Frame = 2 
Query: 1295 CSKPQ-------EGDPDFTETN---------------CHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKT 1789
            C  PQ       +G PD T  N               C W+ C K+F +  EL  H+  +H++  GK  + C W DC R+   F  +  L+ H++ H+  KP++C    C + +S  E L  H R+H+GEKPY+C    C+K F+ +S    H  RTH+  KP  CK+  C KR+ + S+L KH+KT
Sbjct:  670 CPNPQTHEVSKADGAPDMTSANDVSNIPPIKQPEQVICQWDGCNKSFSSAQELNDHLEAVHLT-RGKSEYQCLWHDCHRT---FPQRQKLIRHLKVHSKYKPYKCK--TCKRCFSSEETLVQHTRTHSGEKPYKCHI--CNKKFAISSSLKIHI-RTHTGEKPLQCKI--CGKRFNESSNLSKHIKT 845

HSP 2 Score: 71.633 bits (174), Expect = 4.368e-13
Identity = 39/125 (31.20%), Postives = 70/125 (56.00%), Query Frame = 2 
Query: 1430 QTFVCQWKDCVRSGRPFKA--QYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHG 1798
            +  +CQW  C +S    +    ++  VH+ R  G+  +QC + +C++ + + + L  H++ H+  KPY+C+   C + FS+     +H  RTHS  KPY C +  C K++   SSL+ H++T+ G
Sbjct:  703 EQVICQWDGCNKSFSSAQELNDHLEAVHLTR--GKSEYQCLWHDCHRTFPQRQKLIRHLKVHSKYKPYKCK--TCKRCFSSEETLVQH-TRTHSGEKPYKCHI--CNKKFAISSSLKIHIRTHTG 820
[Close]
BLAST of GLI-1 vs. Ensembl Yeast
Match: AZF1 (Zinc-finger transcription factor; involved in diauxic shift; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000005639])

HSP 1 Score: 91.2781 bits (225), Expect = 4.178e-19
Identity = 51/145 (35.17%), Postives = 73/145 (50.34%), Query Frame = 2 
Query: 1346 WNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKH 1780
            +N  +     ++ELV     +      + T   +  +C    R F     L VH+R H G KP  C +  C KR+++  NL+TH R HTGEKPY C+   C K FS   + A H   TH   KP+VCK+E C K +T   +++ H
Sbjct:  561 FNQTMDILPPKSELV---GGVEKPKGTQNTRAVKKHECPYCHRLFSQATHLEVHVRSHIGYKPFVCDY--CGKRFTQGGNLRTHERLHTGEKPYSCDI--CDKKFSRKGNLAAHL-VTHQKLKPFVCKLENCNKTFTQLGNMKAH 697

HSP 2 Score: 75.8702 bits (185), Expect = 2.294e-14
Identity = 43/119 (36.13%), Postives = 60/119 (50.42%), Query Frame = 2 
Query: 1355 CVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNT 1711
            C + F     L  H+ + HI   G + FVC +  C   G+ F     L  H R HTGEKP+ C    C+K++SR  NL  H+ +H   KP+ C+   C+K F+   +   HQNR H  T
Sbjct:  598 CHRLFSQATHLEVHVRS-HI---GYKPFVCDY--C---GKRFTQGGNLRTHERLHTGEKPYSCDI--CDKKFSRKGNLAAHLVTHQKLKPFVCKLENCNKTFTQLGNMKAHQNRFHKET 705
[Close]
BLAST of GLI-1 vs. Ensembl Yeast
Match: ACE2 (Transcription factor required for septum destruction after cytokinesis; phosphorylation by Cbk1p blocks nuclear exit during M/G1 transition, causing localization to daughter cell nuclei, and also increases Ace2p activity; phosphorylation by Cdc28p and Pho85p prevents nuclear import during cell cycle phases other than cytokinesis; part of RAM network that regulates cellular polarity and morphogenesis; ACE2 has a paralog, SWI5, that arose from the whole genome duplication [Source:SGD;Acc:S000004121])

HSP 1 Score: 74.7146 bits (182), Expect = 4.867e-14
Identity = 33/85 (38.82%), Postives = 50/85 (58.82%), Query Frame = 2 
Query: 1526 EKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKH 1780
            +K  +C +PNCNK + R  N+++HI++H  ++PY C+FPGC KAF    D  +H  +   N K Y+C    C KR+    +L  H
Sbjct:  600 DKLFECLYPNCNKVFKRRYNIRSHIQTHLQDRPYSCDFPGCTKAFVRNHDLIRH--KISHNAKKYICP---CGKRFNREDALMVH 679

HSP 2 Score: 48.521 bits (114), Expect = 5.651e-6
Identity = 27/89 (30.34%), Postives = 44/89 (49.44%), Query Frame = 2 
Query: 1430 QTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNR 1696
            + F C + +C    + FK +Y +  H++ H  ++P+ C FP C K + R  +L  H  SH  +K Y C    C K F+       H++R
Sbjct:  601 KLFECLYPNC---NKVFKRRYNIRSHIQTHLQDRPYSCDFPGCTKAFVRNHDLIRHKISHNAKK-YICP---CGKRFNREDALMVHRSR 682
[Close]
BLAST of GLI-1 vs. Ensembl Yeast
Match: CRZ1 (Transcription factor, activates transcription of stress response genes; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation; rapidly localizes to the nucleus under blue light stress; can be activated in stochastic pulses of nuclear localization in response to calcium [Source:SGD;Acc:S000004972])

HSP 1 Score: 68.5514 bits (166), Expect = 3.567e-12
Identity = 34/88 (38.64%), Postives = 51/88 (57.95%), Query Frame = 2 
Query: 1556 CNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVC-------KVEGCAKRYTDPSSLRKHVKTNHG 1798
            C K+++R  NLK+H+R+HT E+P+ C    C KAF+   DR +H++  H+  K YVC       K  GC K++    +L +H KT  G
Sbjct:  574 CGKKFTRPYNLKSHLRTHTNERPFICSI--CGKAFARQHDRKRHED-LHTGKKRYVCGGKLKDGKPWGCGKKFARSDALGRHFKTESG 658
[Close]
BLAST of GLI-1 vs. Ensembl Yeast
Match: MIG1 (Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase; regulates filamentous growth along with Mig2p in response to glucose depletion; activated in stochastic pulses of nuclear localization, shuttling between cytosol and nucleus depending on external glucose levels and its phosphorylation state [Source:SGD;Acc:S000003003])

HSP 1 Score: 66.6254 bits (161), Expect = 9.926e-12
Identity = 29/65 (44.62%), Postives = 43/65 (66.15%), Query Frame = 2 
Query: 1523 GEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKP 1717
              +PH C  P C++ + RLE+   H+R HTGEKP+ C+FPGC K FS + +  +H+ R H+N+ P
Sbjct:   34 APRPHAC--PICHRAFHRLEHQTRHMRIHTGEKPHACDFPGCVKRFSRSDELTRHR-RIHTNSHP 95

HSP 2 Score: 55.8398 bits (133), Expect = 2.099e-8
Identity = 24/40 (60.00%), Postives = 26/40 (65.00%), Query Frame = 2 
Query: 1505 HMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKP 1624
            HMR HTGEKPH C FP C KR+SR + L  H R HT   P
Sbjct:   56 HMRIHTGEKPHACDFPGCVKRFSRSDELTRHRRIHTNSHP 95
[Close]
BLAST of GLI-1 vs. Ensembl Nematostella
Match: EDO37573 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFG3])

HSP 1 Score: 236.884 bits (603), Expect = 1.327e-72
Identity = 111/154 (72.08%), Postives = 120/154 (77.92%), Query Frame = 2 
Query: 1343 HWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQ 1804
            HW DC   FD+Q  LVKH++  HI    K+ F C W+DC R  RPFKAQYMLVVHMRRHTGEKPH+C    C K YSRLENLKTH+RSHTGE+PY CE  GC KAFSNASDRAKHQNRTHS+ KPYVCKV GC KRYTDPSSLRKH KT HG Q
Sbjct:    2 HWKDCTIVFDSQDSLVKHVNGDHIKKE-KRDFTCYWQDCSREQRPFKAQYMLVVHMRRHTGEKPHKCYHEGCTKAYSRLENLKTHLRSHTGERPYVCEVEGCTKAFSNASDRAKHQNRTHSSVKPYVCKVPGCPKRYTDPSSLRKHTKTVHGEQ 154
[Close]
BLAST of GLI-1 vs. Ensembl Nematostella
Match: EDO45177 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU02])

HSP 1 Score: 203.756 bits (517), Expect = 8.305e-61
Identity = 93/151 (61.59%), Postives = 113/151 (74.83%), Query Frame = 2 
Query: 1337 NCHWNDCVKTFDTQAELVKHISTIHISG-SGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVK 1786
            +C W  C   +  Q +LV+HI  +HI        ++C W+DC R  +PF A+Y LV+HMR H+GEKP++CT P CNK +SRLENLK H+RSHTGEKPY C+FPGC KAFSN+SDRAKHQ RTH +TKPY C+V GC KRYTDPSSLRKH K
Sbjct:    1 SCRWLGCDAVYSEQDDLVRHIEKVHIDQRKADDLYICYWQDCSRQTKPFNARYKLVIHMRVHSGEKPNKCTHPGCNKAFSRLENLKIHMRSHTGEKPYLCQFPGCPKAFSNSSDRAKHQ-RTHLDTKPYACQVPGCPKRYTDPSSLRKHFK 150
[Close]
BLAST of GLI-1 vs. Ensembl Nematostella
Match: EDO44435 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVR5])

HSP 1 Score: 189.504 bits (480), Expect = 2.377e-55
Identity = 86/155 (55.48%), Postives = 109/155 (70.32%), Query Frame = 2 
Query: 1340 CHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQ 1804
            C W  C   F T  +LV H++  HI+      + C+W+ C R+G+ F A+Y +++HMR HTGE+PH+CTF +C K +SRLENLK H RSHTGEKPY C   GC K +SN+SDR KH  RTH   KPY C++EGC KRYTDPSSLRKH+KT HG +
Sbjct:   19 CKWESCCHHFLTLDDLVNHVNEYHITFDKDSEYRCRWQGCNRNGKGFNARYKMLIHMRTHTGERPHKCTFDSCEKSFSRLENLKIHQRSHTGEKPYSCPIEGCDKRYSNSSDRFKH-TRTHYERKPYHCRIEGCEKRYTDPSSLRKHLKTYHGQE 172
[Close]
BLAST of GLI-1 vs. Ensembl Nematostella
Match: NV-ZICC (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK36])

HSP 1 Score: 181.8 bits (460), Expect = 9.996e-52
Identity = 83/160 (51.88%), Postives = 108/160 (67.50%), Query Frame = 2 
Query: 1322 DFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGP 1801
            ++ E       C + F    ++V H+S  H+ G    T VC WKDC R+G PFKA+Y L+ H+R HTGEKP  C FP C K ++R ENLK H R+HTGEKP+ CEFPGC + F+N+SDR KH +  H++ KPY+CKV+GC K YT PSSLRKH+K +  P
Sbjct:   32 EWIEPGSKGKPCGRQFFRMHDIVAHLSEDHVGGPESTTHVCYWKDCARNGLPFKAKYKLINHIRVHTGEKPFACPFPGCGKLFARSENLKIHKRTHTGEKPFICEFPGCDRRFANSSDRKKHSH-VHTSDKPYICKVDGCNKSYTHPSSLRKHMKLHSKP 190

HSP 2 Score: 88.5817 bits (218), Expect = 1.964e-19
Identity = 46/130 (35.38%), Postives = 71/130 (54.62%), Query Frame = 2 
Query: 1313 GDPDFTETNCHWNDCVK---TFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQN 1693
            G P+ T   C+W DC +    F  + +L+ HI  +H   +G++ F C +  C   G+ F     L +H R HTGEKP  C FP C++R++   + K H   HT +KPY C+  GC+K++++ S   KH  
Sbjct:   63 GGPESTTHVCYWKDCARNGLPFKAKYKLINHI-RVH---TGEKPFACPFPGC---GKLFARSENLKIHKRTHTGEKPFICEFPGCDRRFANSSDRKKHSHVHTSDKPYICKVDGCNKSYTHPSSLRKHMK 185
[Close]
BLAST of GLI-1 vs. Ensembl Nematostella
Match: NV-ZICA (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8M8])

HSP 1 Score: 174.866 bits (442), Expect = 3.110e-50
Identity = 84/160 (52.50%), Postives = 108/160 (67.50%), Query Frame = 2 
Query: 1337 NCHWNDCV--------KTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTN 1792
            +C W DC         K F    ELVKHI+  H++G      VC W+ C R+G+PFKA+Y LV H+R HTGEKP  C F +CNK ++R ENLK H R+HTGEKP+ECEF GC++ F+N+SDR KH +  H++ KPY C+  GC K YT PSSLRKH+K +
Sbjct:   16 SCKWIDCTEKVSLLCDKVFSCMDELVKHITIEHVNGRDSTQHVCCWESCDRAGKPFKAKYKLVNHIRVHTGEKPFVCPFSSCNKLFARSENLKIHKRTHTGEKPFECEFKGCNRRFANSSDRKKHSH-VHTSDKPYNCRYSGCEKSYTHPSSLRKHLKAH 174
[Close]
BLAST of GLI-1 vs. Ensembl Medaka
Match: gli3 (GLI family zinc finger 3 [Source:NCBI gene;Acc:101167154])

HSP 1 Score: 279.641 bits (714), Expect = 1.955e-77
Identity = 129/207 (62.32%), Postives = 154/207 (74.40%), Query Frame = 2 
Query: 1238 QLSNVDKLIEKHSDNSYKLCSKPQEGDPD--------FTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGE 1834
            +L   ++L    +D+   +    +EGD D          ETNCHW +C + FDTQ +LV+HI+  HI G  K+ FVC+W++C R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G+
Sbjct:  444 KLKPEEELPSPGADHPEGMTLVKEEGDKDEGKQEPEVVYETNCHWENCCREFDTQEQLVQHINNDHIHGE-KKEFVCRWEECSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGD 649
[Close]
BLAST of GLI-1 vs. Ensembl Medaka
Match: gli3 (GLI family zinc finger 3 [Source:NCBI gene;Acc:101167154])

HSP 1 Score: 279.641 bits (714), Expect = 1.955e-77
Identity = 129/207 (62.32%), Postives = 154/207 (74.40%), Query Frame = 2 
Query: 1238 QLSNVDKLIEKHSDNSYKLCSKPQEGDPD--------FTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGE 1834
            +L   ++L    +D+   +    +EGD D          ETNCHW +C + FDTQ +LV+HI+  HI G  K+ FVC+W++C R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G+
Sbjct:  444 KLKPEEELPSPGADHPEGMTLVKEEGDKDEGKQEPEVVYETNCHWENCCREFDTQEQLVQHINNDHIHGE-KKEFVCRWEECSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGD 649
[Close]
BLAST of GLI-1 vs. Ensembl Medaka
Match: gli1 (GLI family zinc finger 1 [Source:NCBI gene;Acc:101163893])

HSP 1 Score: 277.33 bits (708), Expect = 8.821e-77
Identity = 126/180 (70.00%), Postives = 143/180 (79.44%), Query Frame = 2 
Query: 1307 QEGDPD---FTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGES 1837
            ++G P+     ETNC W  C K FDTQ +LV HI+  HI G  K+ FVC W++C R  RPFKAQYMLVVHMRRHTGEKPH+CTF  CNK YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK +G++
Sbjct:  307 EDGKPEPEAVYETNCRWESCNKEFDTQDQLVHHINNEHIHGE-KKEFVCHWQECSREQRPFKAQYMLVVHMRRHTGEKPHKCTFEGCNKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHITKKHRGDT 485
[Close]
BLAST of GLI-1 vs. Ensembl Medaka
Match: gli2b (GLI family zinc finger 2 [Source:NCBI gene;Acc:101164961])

HSP 1 Score: 273.478 bits (698), Expect = 1.282e-75
Identity = 122/168 (72.62%), Postives = 137/168 (81.55%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGE 1834
            ETNCHW  C K +DTQ +LV HI+  HI G  K+ FVC+W+DC R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK + +
Sbjct:  393 ETNCHWEGCSKEYDTQDQLVHHINNDHIHGE-KKEFVCRWEDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCAKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRSD 559
[Close]
BLAST of GLI-1 vs. Ensembl Medaka
Match: gli2b (GLI family zinc finger 2 [Source:NCBI gene;Acc:101164961])

HSP 1 Score: 273.478 bits (698), Expect = 1.282e-75
Identity = 122/168 (72.62%), Postives = 137/168 (81.55%), Query Frame = 2 
Query: 1331 ETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGE 1834
            ETNCHW  C K +DTQ +LV HI+  HI G  K+ FVC+W+DC R  +PFKAQYMLVVHMRRHTGEKPH+CTF  C K YSRLENLKTH+RSHTGEKPY CE  GC+KAFSNASDRAKHQNRTHSN KPYVCK+ GC KRYTDPSSLRKHVKT HGP+ +  KK + +
Sbjct:  393 ETNCHWEGCSKEYDTQDQLVHHINNDHIHGE-KKEFVCRWEDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCAKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRSD 559
[Close]
BLAST of GLI-1 vs. Planmine SMEST
Match: SMESG000073727.1 (SMESG000073727.1)

HSP 1 Score: 1705.26 bits (4415), Expect = 0.000e+0
Identity = 880/880 (100.00%), Postives = 880/880 (100.00%), Query Frame = 2 
Query:  368 MTSFSNKTRLGKNCRNGKDSRNMNFWNSENSCNINANDCNIPADGNINSANVNYNQNLPCFINQPSCDQWPFVSNFNCFQHQYLVPNHFPYFQNGCVTQNNIPLNYCKATNNEIKHISGENINQCLSNNHLPYVVMNYLSGNATPANELVPNPGSLFNNLNNSSADNSHDSQPMDVGFHLPNSTSFRAGCQSDNHYNSNFRSLLGSKRPRTQASLSDFIDIQTLTRVSQDSLAVRSLXXXXXXXXXXXXXXXXXXXXMGSPPGINQYTFPQSGDTKSFRYDISNEKQEHFQLSNVDKLIEKHSDNSYKLCSKPQEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDGYSSGKYNWDHQLSMKNSSENFIGTHSNSLHTPSSSTQTTNAWSDNLSPNDVAFNILTNLSNNDSXXXXXXXXXXXXXXXXXMNGSNVVAVRTNPTNQAMPNKMRMKTEFITNTNKLTTEMINKFEEDSKFNEMSSVIGALXXXXXXXXXXXXXXXAVNINGEKAQSHFNNSSLSETAAVKLEHYFSHSQNPSIAFEPSKSQLSSFYNHPYNSPSMNSVNNSFGIINCQTPTNIIQDHTPVYFNPRSPYTHQHHVYYNTQHQINGFNSVSCSPCHVYHCNPYYGSTGVPSSTNNQCCCHNAGLVTNGFGDSRLTQSLCSSLSTGSCNLHSTCNYHPSNDRYSNILDENIVSVSMDQLPLLETLSDNLVVCQNKMPFNKNI 3007
            MTSFSNKTRLGKNCRNGKDSRNMNFWNSENSCNINANDCNIPADGNINSANVNYNQNLPCFINQPSCDQWPFVSNFNCFQHQYLVPNHFPYFQNGCVTQNNIPLNYCKATNNEIKHISGENINQCLSNNHLPYVVMNYLSGNATPANELVPNPGSLFNNLNNSSADNSHDSQPMDVGFHLPNSTSFRAGCQSDNHYNSNFRSLLGSKRPRTQASLSDFIDIQTLTRVSQDSLAVRSLHSRSGAGSSIGSIGHLSAASMGSPPGINQYTFPQSGDTKSFRYDISNEKQEHFQLSNVDKLIEKHSDNSYKLCSKPQEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDGYSSGKYNWDHQLSMKNSSENFIGTHSNSLHTPSSSTQTTNAWSDNLSPNDVAFNILTNLSNNDSLIFDADDEDILEIDTLDMNGSNVVAVRTNPTNQAMPNKMRMKTEFITNTNKLTTEMINKFEEDSKFNEMSSVIGALSEVSSGIGSLSSTKSAVNINGEKAQSHFNNSSLSETAAVKLEHYFSHSQNPSIAFEPSKSQLSSFYNHPYNSPSMNSVNNSFGIINCQTPTNIIQDHTPVYFNPRSPYTHQHHVYYNTQHQINGFNSVSCSPCHVYHCNPYYGSTGVPSSTNNQCCCHNAGLVTNGFGDSRLTQSLCSSLSTGSCNLHSTCNYHPSNDRYSNILDENIVSVSMDQLPLLETLSDNLVVCQNKMPFNKNI
Sbjct:    1 MTSFSNKTRLGKNCRNGKDSRNMNFWNSENSCNINANDCNIPADGNINSANVNYNQNLPCFINQPSCDQWPFVSNFNCFQHQYLVPNHFPYFQNGCVTQNNIPLNYCKATNNEIKHISGENINQCLSNNHLPYVVMNYLSGNATPANELVPNPGSLFNNLNNSSADNSHDSQPMDVGFHLPNSTSFRAGCQSDNHYNSNFRSLLGSKRPRTQASLSDFIDIQTLTRVSQDSLAVRSLHSRSGAGSSIGSIGHLSAASMGSPPGINQYTFPQSGDTKSFRYDISNEKQEHFQLSNVDKLIEKHSDNSYKLCSKPQEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDGYSSGKYNWDHQLSMKNSSENFIGTHSNSLHTPSSSTQTTNAWSDNLSPNDVAFNILTNLSNNDSLIFDADDEDILEIDTLDMNGSNVVAVRTNPTNQAMPNKMRMKTEFITNTNKLTTEMINKFEEDSKFNEMSSVIGALSEVSSGIGSLSSTKSAVNINGEKAQSHFNNSSLSETAAVKLEHYFSHSQNPSIAFEPSKSQLSSFYNHPYNSPSMNSVNNSFGIINCQTPTNIIQDHTPVYFNPRSPYTHQHHVYYNTQHQINGFNSVSCSPCHVYHCNPYYGSTGVPSSTNNQCCCHNAGLVTNGFGDSRLTQSLCSSLSTGSCNLHSTCNYHPSNDRYSNILDENIVSVSMDQLPLLETLSDNLVVCQNKMPFNKNI 880
[Close]
BLAST of GLI-1 vs. Planmine SMEST
Match: SMESG000073727.1 (SMESG000073727.1)

HSP 1 Score: 1660.2 bits (4298), Expect = 0.000e+0
Identity = 858/858 (100.00%), Postives = 858/858 (100.00%), Query Frame = 2 
Query:  434 MNFWNSENSCNINANDCNIPADGNINSANVNYNQNLPCFINQPSCDQWPFVSNFNCFQHQYLVPNHFPYFQNGCVTQNNIPLNYCKATNNEIKHISGENINQCLSNNHLPYVVMNYLSGNATPANELVPNPGSLFNNLNNSSADNSHDSQPMDVGFHLPNSTSFRAGCQSDNHYNSNFRSLLGSKRPRTQASLSDFIDIQTLTRVSQDSLAVRSLXXXXXXXXXXXXXXXXXXXXMGSPPGINQYTFPQSGDTKSFRYDISNEKQEHFQLSNVDKLIEKHSDNSYKLCSKPQEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDGYSSGKYNWDHQLSMKNSSENFIGTHSNSLHTPSSSTQTTNAWSDNLSPNDVAFNILTNLSNNDSXXXXXXXXXXXXXXXXXMNGSNVVAVRTNPTNQAMPNKMRMKTEFITNTNKLTTEMINKFEEDSKFNEMSSVIGALXXXXXXXXXXXXXXXAVNINGEKAQSHFNNSSLSETAAVKLEHYFSHSQNPSIAFEPSKSQLSSFYNHPYNSPSMNSVNNSFGIINCQTPTNIIQDHTPVYFNPRSPYTHQHHVYYNTQHQINGFNSVSCSPCHVYHCNPYYGSTGVPSSTNNQCCCHNAGLVTNGFGDSRLTQSLCSSLSTGSCNLHSTCNYHPSNDRYSNILDENIVSVSMDQLPLLETLSDNLVVCQNKMPFNKNI 3007
            MNFWNSENSCNINANDCNIPADGNINSANVNYNQNLPCFINQPSCDQWPFVSNFNCFQHQYLVPNHFPYFQNGCVTQNNIPLNYCKATNNEIKHISGENINQCLSNNHLPYVVMNYLSGNATPANELVPNPGSLFNNLNNSSADNSHDSQPMDVGFHLPNSTSFRAGCQSDNHYNSNFRSLLGSKRPRTQASLSDFIDIQTLTRVSQDSLAVRSLHSRSGAGSSIGSIGHLSAASMGSPPGINQYTFPQSGDTKSFRYDISNEKQEHFQLSNVDKLIEKHSDNSYKLCSKPQEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDGYSSGKYNWDHQLSMKNSSENFIGTHSNSLHTPSSSTQTTNAWSDNLSPNDVAFNILTNLSNNDSLIFDADDEDILEIDTLDMNGSNVVAVRTNPTNQAMPNKMRMKTEFITNTNKLTTEMINKFEEDSKFNEMSSVIGALSEVSSGIGSLSSTKSAVNINGEKAQSHFNNSSLSETAAVKLEHYFSHSQNPSIAFEPSKSQLSSFYNHPYNSPSMNSVNNSFGIINCQTPTNIIQDHTPVYFNPRSPYTHQHHVYYNTQHQINGFNSVSCSPCHVYHCNPYYGSTGVPSSTNNQCCCHNAGLVTNGFGDSRLTQSLCSSLSTGSCNLHSTCNYHPSNDRYSNILDENIVSVSMDQLPLLETLSDNLVVCQNKMPFNKNI
Sbjct:    1 MNFWNSENSCNINANDCNIPADGNINSANVNYNQNLPCFINQPSCDQWPFVSNFNCFQHQYLVPNHFPYFQNGCVTQNNIPLNYCKATNNEIKHISGENINQCLSNNHLPYVVMNYLSGNATPANELVPNPGSLFNNLNNSSADNSHDSQPMDVGFHLPNSTSFRAGCQSDNHYNSNFRSLLGSKRPRTQASLSDFIDIQTLTRVSQDSLAVRSLHSRSGAGSSIGSIGHLSAASMGSPPGINQYTFPQSGDTKSFRYDISNEKQEHFQLSNVDKLIEKHSDNSYKLCSKPQEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQDGYSSGKYNWDHQLSMKNSSENFIGTHSNSLHTPSSSTQTTNAWSDNLSPNDVAFNILTNLSNNDSLIFDADDEDILEIDTLDMNGSNVVAVRTNPTNQAMPNKMRMKTEFITNTNKLTTEMINKFEEDSKFNEMSSVIGALSEVSSGIGSLSSTKSAVNINGEKAQSHFNNSSLSETAAVKLEHYFSHSQNPSIAFEPSKSQLSSFYNHPYNSPSMNSVNNSFGIINCQTPTNIIQDHTPVYFNPRSPYTHQHHVYYNTQHQINGFNSVSCSPCHVYHCNPYYGSTGVPSSTNNQCCCHNAGLVTNGFGDSRLTQSLCSSLSTGSCNLHSTCNYHPSNDRYSNILDENIVSVSMDQLPLLETLSDNLVVCQNKMPFNKNI 858
[Close]
BLAST of GLI-1 vs. Planmine SMEST
Match: SMESG000060276.1 (SMESG000060276.1)

HSP 1 Score: 265.774 bits (678), Expect = 5.621e-80
Identity = 123/171 (71.93%), Postives = 138/171 (80.70%), Query Frame = 2 
Query: 1340 CHWNDCVK-TFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDR 1849
            CHW  C K  FD +  LV HI T HIS   K  ++CQW +C R+ +PFKAQYMLVVHMRRHTGEKPH+C + NC+K YSRLENLKTHIR+HTGEKPY CEF  C+K FSNASDRAKHQNRTHSN KPY CKV+GC KRYTDPSSLRKHVKTNH  ++YA+K  KGESWSDR
Sbjct:   17 CHWESCTKQCFDCET-LVNHIFTKHISECKKPYYICQWNNCGRNKKPFKAQYMLVVHMRRHTGEKPHKCEYSNCDKCYSRLENLKTHIRTHTGEKPYNCEFLSCNKRFSNASDRAKHQNRTHSNQKPYFCKVDGCLKRYTDPSSLRKHVKTNHDNKIYAEKLKKGESWSDR 186
[Close]
BLAST of GLI-1 vs. Planmine SMEST
Match: SMESG000078300.1 (SMESG000078300.1)

HSP 1 Score: 196.052 bits (497), Expect = 6.271e-52
Identity = 88/168 (52.38%), Postives = 114/168 (67.86%), Query Frame = 2 
Query: 1340 CHWNDCVKTFDTQAELVKHISTIHISGSG-KQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESW 1840
            C W DC ++F     LV HI  +H+     K  + C W+ C R  +PF A+Y L++HMR H+GEKP++C +  C+K +SRLENLK H RSHTGE+PY+C++ GC KAFSN+SDRAKHQ RTH +TKPY C V GC KRYTDPSSLRKH K++   Q   +  +    W
Sbjct:  389 CFWIDCYQSFHDCKSLVNHIEKMHVDQRNIKDEYTCFWQGCSRKLKPFNARYKLLIHMRVHSGEKPNKCKYSGCDKAFSRLENLKIHERSHTGERPYQCQYIGCPKAFSNSSDRAKHQ-RTHYDTKPYCCGVAGCGKRYTDPSSLRKHTKSHQNFQSQLNASIDPNLW 555
[Close]
BLAST of GLI-1 vs. Planmine SMEST
Match: SMESG000052644.1 (SMESG000052644.1)

HSP 1 Score: 176.022 bits (445), Expect = 5.597e-47
Identity = 83/162 (51.23%), Postives = 105/162 (64.81%), Query Frame = 2 
Query: 1328 TETNCHWND---------CVKTFDTQAELVKHISTIHISGSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKRYSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKPYVCKVEGCAKRYTDPSSLRKHVK 1786
            TE  C W D         C K F T  E+V H++  H+ G  +    C WK+C R  +PFKA+Y LV H+R HTGEKP QC F +C K ++R ENLK H R+HTGEKP++C+F GC + F+N+SDR KH +  H N KPY CK EGC K YT PSSLRKH++
Sbjct:  177 TEFQCLWLDKHMKEERRTCGKLFYTINEIVNHLTLDHVGGPEQLDHTCYWKNCTRDFKPFKAKYKLVNHLRVHTGEKPFQCPFLSCGKLFARSENLKIHKRTHTGEKPFKCDFEGCDRRFANSSDRKKHMH-VHMNDKPYFCKQEGCDKSYTHPSSLRKHMR 337
The following BLAST results are available for this feature:
BLAST of GLI-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GLI31.697e-7769.02GLI family zinc finger 3 [Source:HGNC Symbol;Acc:H... [more]
GLI31.946e-7769.02GLI family zinc finger 3 [Source:HGNC Symbol;Acc:H... [more]
GLI26.422e-7770.69GLI family zinc finger 2 [Source:HGNC Symbol;Acc:H... [more]
GLI26.422e-7770.69GLI family zinc finger 2 [Source:HGNC Symbol;Acc:H... [more]
GLI13.556e-7468.75GLI family zinc finger 1 [Source:HGNC Symbol;Acc:H... [more]
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BLAST of GLI-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tra-13.120e-5756.04Sex-determining transformer protein 1 [Source:Uni... [more]
ztf-141.905e-4052.63Zinc finger putative Transcription Factor family ... [more]
ref-27.837e-3945.03REgulator of Fusion [Source:UniProtKB/TrEMBL;Acc:... [more]
ref-28.814e-3945.03REgulator of Fusion [Source:UniProtKB/TrEMBL;Acc:... [more]
ref-28.814e-3945.03REgulator of Fusion [Source:UniProtKB/TrEMBL;Acc:... [more]
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BLAST of GLI-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ci1.240e-8058.17gene:FBgn0004859 transcript:FBtr0306168[more]
ci2.573e-8058.17gene:FBgn0004859 transcript:FBtr0089178[more]
lmd2.011e-5355.36gene:FBgn0039039 transcript:FBtr0084364[more]
sug2.928e-5158.28gene:FBgn0033782 transcript:FBtr0331985[more]
sug9.264e-5158.28gene:FBgn0033782 transcript:FBtr0087789[more]
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BLAST of GLI-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gli16.827e-7974.56GLI family zinc finger 1 [Source:ZFIN;Acc:ZDB-GENE... [more]
gli32.096e-7872.35GLI family zinc finger 3 [Source:ZFIN;Acc:ZDB-GENE... [more]
gli2b1.583e-7769.44GLI family zinc finger 2b [Source:ZFIN;Acc:ZDB-GEN... [more]
gli2a1.804e-7772.78GLI family zinc finger 2a [Source:ZFIN;Acc:ZDB-GEN... [more]
gli2a2.018e-7772.78GLI family zinc finger 2a [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of GLI-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GLI14.531e-8168.18GLI family zinc finger 1 [Source:NCBI gene;Acc:100... [more]
GLI18.456e-8168.18GLI family zinc finger 1 [Source:NCBI gene;Acc:100... [more]
cep1641.828e-7769.02centrosomal protein 164kDa [Source:Xenbase;Acc:XB-... [more]
shmt12.576e-7658.15serine hydroxymethyltransferase 1 (soluble) [Sourc... [more]
shmt13.846e-7658.15serine hydroxymethyltransferase 1 (soluble) [Sourc... [more]
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BLAST of GLI-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Gli31.986e-7773.21GLI-Kruppel family member GLI3 [Source:MGI Symbol;... [more]
Gli26.389e-7770.69GLI-Kruppel family member GLI2 [Source:MGI Symbol;... [more]
Gli15.865e-7469.14GLI-Kruppel family member GLI1 [Source:MGI Symbol;... [more]
Glis32.875e-5959.26GLIS family zinc finger 3 [Source:MGI Symbol;Acc:M... [more]
Glis32.027e-5858.90GLIS family zinc finger 3 [Source:MGI Symbol;Acc:M... [more]
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BLAST of GLI-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P19538|CI_DROME2.579e-7958.17Transcriptional activator cubitus interruptus OS=D... [more]
sp|Q91690|GLI1_XENLA2.781e-7967.68Zinc finger protein GLI1 (Fragment) OS=Xenopus lae... [more]
sp|P55878|GLI1_CHICK4.360e-7970.22Zinc finger protein GLI1 (Fragment) OS=Gallus gall... [more]
sp|P55879|GLI2_CHICK5.380e-7973.49Zinc finger protein GLI2 (Fragment) OS=Gallus gall... [more]
sp|Q9IA31|GLI3_CHICK7.593e-7769.02Transcriptional activator GLI3 (Fragment) OS=Gallu... [more]
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BLAST of GLI-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
D2ILS30.000e+099.55GLI-1 OS=Schmidtea mediterranea OX=79327 GN=gli-1 ... [more]
D0VYP40.000e+080.07GLI family zinc finger protein OS=Dugesia japonica... [more]
A0A0X3PQV54.121e-9377.47Uncharacterized protein (Fragment) OS=Schistocepha... [more]
A0A4Z2D0L81.899e-9075.65Transcriptional activator protein OS=Schistosoma j... [more]
A0A430QLR61.014e-8978.57Transcriptional activator cubitus interruptus OS=S... [more]
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BLAST of GLI-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gli15.752e-7975.15GLI family zinc finger 1 [Source:ZFIN;Acc:ZDB-GENE... [more]
gli32.794e-7764.95GLI family zinc finger 3 [Source:ZFIN;Acc:ZDB-GENE... [more]
gli2a2.865e-7768.68GLI family zinc finger 2 [Source:NCBI gene;Acc:103... [more]
gli2b7.942e-7772.62zinc finger protein GLI2-like [Source:NCBI gene;Ac... [more]
glis35.807e-6154.84GLIS family zinc finger 3 [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of GLI-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000008614.17.027e-6878.63pep scaffold:Pmarinus_7.0:GL479003:10005:19084:-1 ... [more]
glis2b2.420e-5257.24GLIS family zinc finger 2b [Source:ZFIN;Acc:ZDB-GE... [more]
ENSPMAT00000003448.12.337e-4350.32pep scaffold:Pmarinus_7.0:GL477543:42863:56609:1 g... [more]
ENSPMAT00000003451.12.416e-4250.66pep scaffold:Pmarinus_7.0:GL477543:42884:56609:1 g... [more]
znf143b2.397e-2841.67zinc finger protein 143b [Source:NCBI gene;Acc:393... [more]
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BLAST of GLI-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
ZAP12.928e-2434.76Zinc-regulated transcription factor; binds to zinc... [more]
AZF14.178e-1935.17Zinc-finger transcription factor; involved in diau... [more]
ACE24.867e-1438.82Transcription factor required for septum destructi... [more]
CRZ13.567e-1238.64Transcription factor, activates transcription of s... [more]
MIG19.926e-1244.62Transcription factor involved in glucose repressio... [more]
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BLAST of GLI-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO375731.327e-7272.08Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO451778.305e-6161.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO444352.377e-5555.48Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
NV-ZICC9.996e-5251.88Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
NV-ZICA3.110e-5052.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of GLI-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gli31.955e-7762.32GLI family zinc finger 3 [Source:NCBI gene;Acc:101... [more]
gli31.955e-7762.32GLI family zinc finger 3 [Source:NCBI gene;Acc:101... [more]
gli18.821e-7770.00GLI family zinc finger 1 [Source:NCBI gene;Acc:101... [more]
gli2b1.282e-7572.62GLI family zinc finger 2 [Source:NCBI gene;Acc:101... [more]
gli2b1.282e-7572.62GLI family zinc finger 2 [Source:NCBI gene;Acc:101... [more]
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BLAST of GLI-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000073727.10.000e+0100.00SMESG000073727.1[more]
SMESG000073727.10.000e+0100.00SMESG000073727.1[more]
SMESG000060276.15.621e-8071.93SMESG000060276.1[more]
SMESG000078300.16.271e-5252.38SMESG000078300.1[more]
SMESG000052644.15.597e-4751.23SMESG000052644.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30011047
GenBankACZ64514.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011047 ID=SMED30011047|Name=GLI-1|organism=Schmidtea mediterranea sexual|type=transcript|length=3085bp
GTAACTGCATGGAACATGATAAGATTGTTATCTCTCAATTTTACCTGTAC
ATTTTTGAGTGTGCCCGACGTGTAATGTGGGTGTCATGTTAGGTGTGTAC
CGGTGTGTGCCAGGTGTGTGTATGTGACAGTGCAATCATAACGAGGACAA
TCAGATTTGATAGATTTTTAAGTGAGTATCTGTAAGTGATGGACAATATC
AAATTATTTGATTAGGTTCTGCCATAATATCAATTATTTGTGCTCTACTG
AAATTAATTTTACAATGAGTAATAGACCTGTCGAACCGTTTTAATTATTG
CTTTTGGATGAATTAATTTTGTTAACATAAGATTTACTGCTTATATTTCA
AAAAAAACCAATAATTTATGACATCTTTCAGCAATAAAACTCGGCTAGGA
AAAAATTGTCGAAATGGAAAGGATTCTCGAAACATGAATTTTTGGAACTC
AGAAAATTCATGCAATATCAATGCAAACGATTGTAACATTCCTGCAGATG
GCAATATCAATAGTGCAAATGTAAATTATAATCAAAATTTACCCTGTTTC
ATTAATCAGCCGAGCTGTGATCAGTGGCCTTTTGTTAGCAATTTCAACTG
TTTTCAACATCAATATTTGGTTCCAAATCATTTTCCGTATTTTCAGAATG
GTTGTGTTACACAGAATAATATTCCATTAAATTACTGTAAGGCGACAAAC
AATGAAATCAAACATATTTCGGGAGAAAATATCAATCAGTGTCTTTCAAA
TAATCATTTGCCTTATGTTGTTATGAATTATTTATCAGGTAATGCCACGC
CAGCAAACGAACTAGTTCCTAATCCAGGATCACTATTCAACAACCTAAAC
AATTCTAGTGCTGATAATTCACACGATTCTCAACCTATGGATGTTGGCTT
TCATTTACCTAATTCGACATCTTTTCGAGCTGGATGTCAATCTGATAATC
ACTATAATAGCAATTTTCGATCATTATTAGGGTCAAAGCGTCCAAGAACA
CAAGCATCCCTATCTGATTTTATAGATATTCAAACACTTACTAGAGTATC
ACAAGATTCTTTAGCGGTCCGAAGTTTACATTCAAGAAGTGGGGCTGGAT
CTAGTATAGGATCAATTGGTCATTTATCAGCTGCATCAATGGGTAGTCCG
CCCGGAATTAATCAGTATACGTTTCCCCAGTCAGGGGATACAAAATCCTT
TCGATATGACATTTCGAATGAAAAACAAGAACATTTCCAACTTTCAAATG
TGGATAAATTAATTGAAAAGCACTCTGATAATTCTTACAAACTTTGTTCC
AAGCCTCAAGAAGGTGATCCGGATTTCACAGAAACGAATTGTCATTGGAA
TGATTGTGTCAAAACATTTGATACACAGGCAGAATTGGTCAAACACATTT
CAACAATCCATATTAGTGGAAGTGGAAAGCAAACTTTCGTTTGCCAGTGG
AAAGATTGTGTTCGATCCGGGAGACCTTTTAAAGCGCAATACATGTTGGT
GGTACACATGAGAAGACATACTGGTGAGAAACCACATCAATGTACATTTC
CAAATTGTAACAAACGATATTCACGATTAGAGAATCTCAAAACTCATATC
AGGTCTCATACCGGAGAAAAGCCTTATGAGTGTGAATTCCCTGGATGTCA
TAAAGCTTTTAGTAATGCATCAGATCGAGCAAAACATCAAAATCGTACTC
ACAGTAACACTAAACCATATGTATGCAAAGTAGAAGGATGTGCAAAAAGG
TACACGGATCCTAGCTCTTTACGAAAACATGTCAAGACAAATCATGGACC
ACAAGTCTATGCCGATAAAAAAATGAAAGGAGAAAGTTGGAGTGATCGAT
GTCAATCCAAACAAGATGGTTATTCGTCTGGAAAATACAATTGGGATCAT
CAATTATCAATGAAAAATTCATCAGAAAATTTTATTGGAACACATTCAAA
TAGTTTACATACTCCTTCTTCATCAACTCAAACCACAAATGCATGGAGTG
ATAATTTGAGTCCTAATGATGTAGCATTTAACATTTTAACGAATTTAAGT
AATAATGATTCACTTATTTTCGATGCAGATGATGAAGATATATTAGAAAT
TGATACTTTAGACATGAATGGAAGCAATGTTGTTGCGGTTAGAACGAATC
CTACGAATCAAGCAATGCCGAATAAGATGCGTATGAAAACGGAGTTTATT
ACAAATACTAATAAATTAACCACAGAAATGATCAATAAGTTTGAAGAAGA
TTCAAAATTCAATGAAATGTCTTCTGTGATAGGCGCTCTTTCAGAAGTTA
GTTCTGGAATTGGCTCTCTTAGTTCTACAAAAAGTGCTGTGAATATAAAT
GGTGAAAAAGCTCAGTCTCATTTCAACAACTCTTCACTTTCTGAAACCGC
GGCAGTAAAACTCGAGCATTATTTTTCACATTCTCAAAATCCATCTATAG
CATTTGAACCATCCAAATCTCAGCTATCTTCATTCTACAATCACCCTTAT
AATTCACCTTCAATGAACTCTGTAAATAATTCTTTTGGTATAATAAATTG
CCAAACTCCGACAAATATCATTCAAGATCACACGCCAGTTTATTTCAATC
CCCGTTCTCCATATACTCATCAGCATCATGTATATTACAATACTCAACAT
CAGATCAACGGATTTAACTCTGTTTCATGTTCACCCTGTCATGTATATCA
CTGTAATCCGTATTACGGATCGACGGGAGTTCCCTCCTCAACAAACAACC
AATGCTGTTGTCACAATGCGGGACTCGTTACAAATGGATTCGGTGACAGC
AGACTGACTCAATCTTTATGTTCATCTCTCTCAACTGGTTCGTGCAATCT
TCACTCAACTTGCAATTATCATCCATCTAATGATAGATATTCAAACATTC
TTGATGAGAATATAGTTTCAGTATCAATGGACCAGCTGCCATTGTTGGAA
ACGTTAAGTGATAATCTAGTAGTTTGTCAAAATAAAATGCCTTTCAACAA
AAACATTTGAAATCAGCGATCATAAAAACTTGTGCCAAATGAAATCTTAG
CCAGATGTCGATATAATATTGCATGGAGAGATCGG
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protein sequence of SMED30011047-orf-1

>SMED30011047-orf-1 ID=SMED30011047-orf-1|Name=SMED30011047-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=881bp
MTSFSNKTRLGKNCRNGKDSRNMNFWNSENSCNINANDCNIPADGNINSA
NVNYNQNLPCFINQPSCDQWPFVSNFNCFQHQYLVPNHFPYFQNGCVTQN
NIPLNYCKATNNEIKHISGENINQCLSNNHLPYVVMNYLSGNATPANELV
PNPGSLFNNLNNSSADNSHDSQPMDVGFHLPNSTSFRAGCQSDNHYNSNF
RSLLGSKRPRTQASLSDFIDIQTLTRVSQDSLAVRSLHSRSGAGSSIGSI
GHLSAASMGSPPGINQYTFPQSGDTKSFRYDISNEKQEHFQLSNVDKLIE
KHSDNSYKLCSKPQEGDPDFTETNCHWNDCVKTFDTQAELVKHISTIHIS
GSGKQTFVCQWKDCVRSGRPFKAQYMLVVHMRRHTGEKPHQCTFPNCNKR
YSRLENLKTHIRSHTGEKPYECEFPGCHKAFSNASDRAKHQNRTHSNTKP
YVCKVEGCAKRYTDPSSLRKHVKTNHGPQVYADKKMKGESWSDRCQSKQD
GYSSGKYNWDHQLSMKNSSENFIGTHSNSLHTPSSSTQTTNAWSDNLSPN
DVAFNILTNLSNNDSLIFDADDEDILEIDTLDMNGSNVVAVRTNPTNQAM
PNKMRMKTEFITNTNKLTTEMINKFEEDSKFNEMSSVIGALSEVSSGIGS
LSSTKSAVNINGEKAQSHFNNSSLSETAAVKLEHYFSHSQNPSIAFEPSK
SQLSSFYNHPYNSPSMNSVNNSFGIINCQTPTNIIQDHTPVYFNPRSPYT
HQHHVYYNTQHQINGFNSVSCSPCHVYHCNPYYGSTGVPSSTNNQCCCHN
AGLVTNGFGDSRLTQSLCSSLSTGSCNLHSTCNYHPSNDRYSNILDENIV
SVSMDQLPLLETLSDNLVVCQNKMPFNKNI*
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Aliases
The feature 'GLI-1' has the following synonyms
Synonym
GLI-1
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000101muscle cell
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0003104enteric muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR036236Znf_C2H2_sf
IPR015880Znf_C2H2-like
IPR013087Znf_C2H2_type
IPR007087Znf_C2H2
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0046872metal ion binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR013087Zinc finger C2H2-typeSMARTSM00355c2h2final6coord: 451..476
e-value: 0.0012
score: 28.1
coord: 390..414
e-value: 0.0022
score: 27.2
coord: 357..384
e-value: 3.9
score: 16.5
coord: 420..445
e-value: 0.0073
score: 25.5
coord: 323..348
e-value: 0.061
score: 22.4
IPR013087Zinc finger C2H2-typePFAMPF00096zf-C2H2coord: 390..414
e-value: 0.0019
score: 18.6
coord: 357..384
e-value: 0.0025
score: 18.2
coord: 420..445
e-value: 0.013
score: 15.9
coord: 451..476
e-value: 0.002
score: 18.4
coord: 325..348
e-value: 0.0021
score: 18.4
IPR013087Zinc finger C2H2-typePROSITEPS00028ZINC_FINGER_C2H2_1coord: 392..414
IPR013087Zinc finger C2H2-typePROSITEPS00028ZINC_FINGER_C2H2_1coord: 325..348
IPR013087Zinc finger C2H2-typePROSITEPS00028ZINC_FINGER_C2H2_1coord: 453..476
IPR013087Zinc finger C2H2-typePROSITEPS00028ZINC_FINGER_C2H2_1coord: 422..445
IPR013087Zinc finger C2H2-typePROSITEPS50157ZINC_FINGER_C2H2_2coord: 420..450
score: 13.027
IPR013087Zinc finger C2H2-typePROSITEPS50157ZINC_FINGER_C2H2_2coord: 390..419
score: 14.627
IPR013087Zinc finger C2H2-typePROSITEPS50157ZINC_FINGER_C2H2_2coord: 323..348
score: 8.559
IPR013087Zinc finger C2H2-typePROSITEPS50157ZINC_FINGER_C2H2_2coord: 357..389
score: 11.468
IPR013087Zinc finger C2H2-typePROSITEPS50157ZINC_FINGER_C2H2_2coord: 451..476
score: 9.598
NoneNo IPR availableGENE3DG3DSA:3.30.160.60coord: 418..446
e-value: 8.6E-11
score: 43.6
NoneNo IPR availableGENE3DG3DSA:3.30.160.60coord: 449..477
e-value: 2.9E-13
score: 51.5
NoneNo IPR availableGENE3DG3DSA:3.30.160.60coord: 356..387
e-value: 4.4E-13
score: 51.0
NoneNo IPR availableGENE3DG3DSA:3.30.160.60coord: 388..417
e-value: 6.1E-13
score: 50.4
NoneNo IPR availableGENE3DG3DSA:3.30.160.60coord: 322..352
e-value: 1.9E-10
score: 42.4
NoneNo IPR availablePANTHERPTHR45718FAMILY NOT NAMEDcoord: 311..690
NoneNo IPR availablePANTHERPTHR45718:SF4TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUScoord: 311..690
IPR036236Zinc finger C2H2 superfamilySUPERFAMILYSSF57667beta-beta-alpha zinc fingerscoord: 323..351
IPR036236Zinc finger C2H2 superfamilySUPERFAMILYSSF57667beta-beta-alpha zinc fingerscoord: 418..474
IPR036236Zinc finger C2H2 superfamilySUPERFAMILYSSF57667beta-beta-alpha zinc fingerscoord: 371..428