DNA-directed RNA polymerase II subunit RPB3

Overview
NameDNA-directed RNA polymerase II subunit RPB3
Smed IDSMED30011039
Length (bp)1074
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of DNA-directed RNA polymerase II subunit RPB3 (SMED30011039) t-SNE clustered cells

Violin plots show distribution of expression levels for DNA-directed RNA polymerase II subunit RPB3 (SMED30011039) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30011039

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30011039h1SMcG0000269 SmedASXL_004038SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30011039h1SMcG0000269 dd_Smed_v4_32569_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30011039h1SMcG0000269 dd_Smed_v4_32569_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30011039h1SMcG0000269 dd_Smed_v4_32569_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
prepharyngeal regionSMED30011039h1SMcG0000269 dd_Smed_v6_32569_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Human
Match: POLR2C (RNA polymerase II subunit C [Source:HGNC Symbol;Acc:HGNC:9189])

HSP 1 Score: 281.952 bits (720), Expect = 1.435e-93
Identity = 142/263 (53.99%), Postives = 190/263 (72.24%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGED--GDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            MPYANQ  + + E  DE +KF +E+T L+VANSIRR   A+VP IAI WV +  NS++LHDEFI+ R+GLIPL SDDIVD+L  + +C C +FCP+CS+E  LDV C+++  + VTS DL +++PRV+P T R  ++   D  EQ+ ILIVK+R+ Q L+LR  AKK   K+H K+ PT+ V FEYDPDN+LRH +  KPE+WPKSEYS+L   E QAP++  G P +F++ VES GSL+P+ IVLSAL  LK+KL  +Q  L
Sbjct:    1 MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQL 263
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Human
Match: POLR1C (RNA polymerase I and III subunit C [Source:HGNC Symbol;Acc:HGNC:20194])

HSP 1 Score: 62.3882 bits (150), Expect = 3.015e-10
Identity = 74/294 (25.17%), Postives = 125/294 (42.52%), Query Frame = 1 
Query:  127 VLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSAD---------LKTSNPRVVPATFRIGEDGDLTEQ-------EPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQ-LKPG-----EHQAP---------FNTYG-----------------TPNKFFFTVESAGSLKPQNIVLSALRVLKEK 864
            V++++EN    ++F +     ++AN+ RR   A+VPT+A+  V V  N++++ DE ++ R+GLIP+ +D    RL         +     +++  L V C      +  S+D         + T +   +P    +G   DL  +       + ILI ++R  Q + L +   K I KDH KF P ++  +   PD +    LL   E     E S+   PG     E Q            +T+                    + + F+VES G L P  +V  A++VL  K
Sbjct:   53 VVHMDENS---LEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHAD---PRLFEYRNQGDEEGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHKVYTRHMTWIP----LGNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDIT----LLEPVEGEAAEELSRCFSPGVIEVQEVQGKKVARVANPRLDTFSREIFRNEKLKKVVRLARVRDHYIFSVESTGVLPPDVLVSEAIKVLMGK 332
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Human
Match: POLR1C (RNA polymerase I and III subunit C [Source:HGNC Symbol;Acc:HGNC:20194])

HSP 1 Score: 61.6178 bits (148), Expect = 4.578e-10
Identity = 53/199 (26.63%), Postives = 95/199 (47.74%), Query Frame = 1 
Query:  127 VLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSAD---------LKTSNPRVVPATFRIGEDGDLTEQ-------EPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSL 675
            V++++EN    ++F +     ++AN+ RR   A+VPT+A+  V V  N++++ DE ++ R+GLIP+ +D    RL         +     +++  L V C      +  S+D         + T +   +P    +G   DL  +       + ILI ++R  Q + L +   K I KDH KF P ++  +   PD +L
Sbjct:   53 VVHMDENS---LEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHAD---PRLFEYRNQGDEEGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHKVYTRHMTWIP----LGNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDITL 241
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Human
Match: POLR1C (RNA polymerase I and III subunit C [Source:HGNC Symbol;Acc:HGNC:20194])

HSP 1 Score: 61.6178 bits (148), Expect = 4.578e-10
Identity = 53/199 (26.63%), Postives = 95/199 (47.74%), Query Frame = 1 
Query:  127 VLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSAD---------LKTSNPRVVPATFRIGEDGDLTEQ-------EPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSL 675
            V++++EN    ++F +     ++AN+ RR   A+VPT+A+  V V  N++++ DE ++ R+GLIP+ +D    RL         +     +++  L V C      +  S+D         + T +   +P    +G   DL  +       + ILI ++R  Q + L +   K I KDH KF P ++  +   PD +L
Sbjct:   53 VVHMDENS---LEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHAD---PRLFEYRNQGDEEGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHKVYTRHMTWIP----LGNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDITL 241
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Human
Match: POLR1C (RNA polymerase I and III subunit C [Source:HGNC Symbol;Acc:HGNC:20194])

HSP 1 Score: 61.2326 bits (147), Expect = 6.476e-10
Identity = 54/199 (27.14%), Postives = 95/199 (47.74%), Query Frame = 1 
Query:  127 VLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSAD---------LKTSNPRVVPATFRIGEDGDLTEQ-------EPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSL 675
            V++++EN  EF    ++    ++AN+ RR   A+VPT+A+  V V  N++++ DE ++ R+GLIP+ +D    RL         +     +++  L V C      +  S+D         + T +   +P    +G   DL  +       + ILI ++R  Q + L +   K I KDH KF P ++  +   PD +L
Sbjct:   53 VVHMDENSLEFDMVGID---AAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHAD---PRLFEYRNQGDEEGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHKVYTRHMTWIP----LGNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDITL 241
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Celegans
Match: rpb-3 (RNA Polymerase II (B) subunit [Source:UniProtKB/TrEMBL;Acc:Q93338])

HSP 1 Score: 214.157 bits (544), Expect = 1.906e-67
Identity = 121/276 (43.84%), Postives = 164/276 (59.42%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADL-------KTSNPRVVPATFRIGEDGD-LTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQL--KPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKL----LAVQNSLE 891
            MPYANQ  + V E  ++ IKF L DT LSVANS+RR   A+VPTIAI WV +  N+++LHDEFI+ R+GLIP  SD  V+++    +C C++FC +CSI   L + C DE   +VT+  L        T  P    A    G   D    +E ILIVK+R+ Q L L+   KK   K+H K+ PT  V FEYDPDN+LRH +    E+WP+S++S L     E +APF     PNKF+F++E  G+L  Q IV   + +LK KL    +A+ N L+
Sbjct:    1 MPYANQPNIEVTELTNDIIKFVLWDTDLSVANSLRRVFMAEVPTIAIDWVQIETNTSVLHDEFIAHRMGLIPFISDYHVEKMQYTRDCECAEFCDECSIPFILQMKCKDEATLAVTTEHLMPMHNLDTTVRPACGKALRERGSTRDEFHNREEILIVKLRKGQELNLKAYVKKGFGKEHAKWNPTCGVAFEYDPDNALRHTIYPNVEEWPRSDHSSLPEDSTEKEAPFEPDNKPNKFWFSIEGTGALPAQRIVTMGIGILKRKLEELNMALSNELQ 276
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Celegans
Match: rpac-40 (RNA Polymerase I/III (A/C) shared subunit [Source:UniProtKB/TrEMBL;Acc:Q9UAY9])

HSP 1 Score: 65.4698 bits (158), Expect = 1.370e-11
Identity = 68/326 (20.86%), Postives = 131/326 (40.18%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEF-------------IKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSD------------DIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFR----IGEDGDLTEQ-------EPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQ-----LKPGEHQAPF-----------NTY------------GTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSLE 891
            + Y +    ++ E CD+              ++F +      +AN++RR   A+VPT+A+  +++ +N++++ DE +  R+GL+PL  D             I ++ V   E P  D   +   ++++    +     + T       N  V    F       +    TE+       + IL+ K+R  Q ++    A K I +DH KF P ++  +   P   L   +  +  +  KS +S+      K G  +              N +                 F F+VES G+LK   +V+ A +V++ K  +++  +E
Sbjct:   37 VEYDDTKQFDINEYCDQIQVAMVNESDDGMTLEFDITRIEAPIANALRRVLIAEVPTMALEKIYLYQNTSVIQDEVLCHRLGLLPLRVDPRGFQFPKEKVVGINEKGVDCDEEPEGDPAKNLIFKINVSCTKNRNAVPTATDPKQLYHNSSVYSRAFEWVPIADQKTQFTEEAHPRMVSDDILVAKLRPGQEIEASCHAVKGIGRDHAKFSPVATASYRLLPTIRLNAEISGEAAERLKSVFSEGVIAIEKKGAKRIAVVKDARKDTCSRNVFRHEDLSKVVQLGKNKQHFIFSVESTGALKSSELVVEACKVMEIKCRSLRKQIE 362
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Fly
Match: RpII33 (gene:FBgn0026373 transcript:FBtr0080544)

HSP 1 Score: 279.641 bits (714), Expect = 4.763e-93
Identity = 142/264 (53.79%), Postives = 190/264 (71.97%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIG--EDGDLTE-QEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            MPYANQ  + + E  D+ +KF LEDT LSVANS+RR   A+ PT+AI WV +  NST+L DEF++ R+GLIPL SDD+V+RL    +C C DFCP+CS+E  LDV C +E  + VT+ADLK+SN +V+P T R    ED +  E  + ILI+K+R+ Q LKLR  AKK   K+H K+ PT+ V FEYDPDNS+RH L  KP++WPKSE+++L+  +++AP+N    PNKFFF VESAG+LKP+NIV+  ++VLK KL  +Q  L
Sbjct:    1 MPYANQPSVQITELTDDNVKFVLEDTELSVANSLRRVFIAETPTLAIDWVQLEANSTVLSDEFLAHRIGLIPLISDDVVERLQYTRDCICLDFCPECSVEFTLDVKCSEEQTRHVTTADLKSSNAKVLPVTSRNQGEEDNEYGESNDEILIIKLRKGQELKLRAYAKKGFGKEHAKWNPTAGVCFEYDPDNSMRHTLYPKPDEWPKSEHTELEDDQYEAPYNWEAKPNKFFFNVESAGALKPENIVVMGVQVLKNKLSNLQTQL 264
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Fly
Match: CG3756 (gene:FBgn0031657 transcript:FBtr0078994)

HSP 1 Score: 82.8037 bits (203), Expect = 1.782e-17
Identity = 70/292 (23.97%), Postives = 129/292 (44.18%), Query Frame = 1 
Query:  130 LNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGEDGDLTE----------QEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPG-----EHQAPF-----------NTYGTP------------NKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSLE 891
            + +  N ++ ++F L   + ++AN+ RR   +DVP++AI  V++  N++++ DE ++ R+GL+PL +D  +    +               EL +      +  K  ++ D    N +V     +    G   +           + ILI ++R    L LR++A K + +DH KF P ++  +   P   L   +  K     ++ +S   PG     E++  +           N Y  P            + + F+VES G+LKP  I L A++VLK K  A+ + +E
Sbjct:   43 IKIVRNDEDGLEFDLIGVYPAIANAFRRLMLSDVPSMAIEKVYIYNNTSIIQDEVLAHRMGLLPLRADPRLFAYRTEESTEAGTEQDTLEFELKVKCSRRRDAGKDQSNFDDIYKNHKVYSGHLKWLPKGKQAQIYSESAVNCIHDDILIAQLRPGHELDLRLVAVKGLGRDHAKFSPVATATYRLLPMIKLNREVTGKDAYLLQNCFS---PGVIGIDENETAYVKDARYDTCSRNVYRYPQLNDAVTLARIRDHYIFSVESVGALKPDVIFLEAVKVLKRKCRALIDEIE 331
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Zebrafish
Match: polr2c (polymerase (RNA) II (DNA directed) polypeptide C [Source:ZFIN;Acc:ZDB-GENE-030131-6609])

HSP 1 Score: 280.026 bits (715), Expect = 5.551e-93
Identity = 138/263 (52.47%), Postives = 191/263 (72.62%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGED--GDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            MPYANQ  + + E  DE +KF +E+T L+VANSIRR   ++VPTIAI WV +  NS++LHDEF++ RVGLIPLTSDDIVD++  + +C C DFCP+CS+EL LDV C ++  + VTS DL ++NPRV+P T R  ++   D  EQ+ IL+VK+R+ Q L+LR  AKK   K+H K+ PT+ V FEYDPDN+LRH +   P++WPKSEYS+++    QA ++  G P +F++ VES GSL+P+ IV+SAL +LK+KL  +Q  L
Sbjct:    1 MPYANQPTVKITELSDENVKFVIENTDLAVANSIRRVFMSEVPTIAIDWVQIDANSSVLHDEFVAHRVGLIPLTSDDIVDKMQYSRDCTCDDFCPECSVELTLDVRCTEDQTRHVTSRDLLSNNPRVIPVTSRSRDNDPNDYVEQDDILLVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPIPQEWPKSEYSEIEEDGVQAQYDPNGKPERFYYNVESCGSLRPETIVMSALAMLKKKLSDLQTQL 263
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Zebrafish
Match: polr2c (polymerase (RNA) II (DNA directed) polypeptide C [Source:ZFIN;Acc:ZDB-GENE-030131-6609])

HSP 1 Score: 254.218 bits (648), Expect = 5.051e-83
Identity = 132/266 (49.62%), Postives = 184/266 (69.17%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVS---NSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGED--GDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            MPYANQ  + + E  DE +KF +E+T L+VANSIRR   ++VPTIAI WV +  NS++LHDEF++ RVG I       + RL+    NS+C C DFCP+CS+EL LDV C ++  + VTS DL ++NPRV+P T R  ++   D  EQ+ IL+VK+R+ Q L+LR  AKK   K+H K+ PT+ V FEYDPDN+LRH +   P++WPKSEYS+++    QA ++  G P +F++ VES GSL+P+ IV+SAL +LK+KL  +Q  L
Sbjct:    1 MPYANQPTVKITELSDENVKFVIENTDLAVANSIRRVFMSEVPTIAIDWVQIDANSSVLHDEFVAHRVGAI-------IIRLMFYRINSDCTCDDFCPECSVELTLDVRCTEDQTRHVTSRDLLSNNPRVIPVTSRSRDNDPNDYVEQDDILLVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPIPQEWPKSEYSEIEEDGVQAQYDPNGKPERFYYNVESCGSLRPETIVMSALAMLKKKLSDLQTQL 259
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Zebrafish
Match: polr2c (polymerase (RNA) II (DNA directed) polypeptide C [Source:ZFIN;Acc:ZDB-GENE-030131-6609])

HSP 1 Score: 254.218 bits (648), Expect = 5.051e-83
Identity = 132/266 (49.62%), Postives = 184/266 (69.17%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVS---NSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGED--GDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            MPYANQ  + + E  DE +KF +E+T L+VANSIRR   ++VPTIAI WV +  NS++LHDEF++ RVG I       + RL+    NS+C C DFCP+CS+EL LDV C ++  + VTS DL ++NPRV+P T R  ++   D  EQ+ IL+VK+R+ Q L+LR  AKK   K+H K+ PT+ V FEYDPDN+LRH +   P++WPKSEYS+++    QA ++  G P +F++ VES GSL+P+ IV+SAL +LK+KL  +Q  L
Sbjct:    1 MPYANQPTVKITELSDENVKFVIENTDLAVANSIRRVFMSEVPTIAIDWVQIDANSSVLHDEFVAHRVGAI-------IIRLMFYRINSDCTCDDFCPECSVELTLDVRCTEDQTRHVTSRDLLSNNPRVIPVTSRSRDNDPNDYVEQDDILLVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPIPQEWPKSEYSEIEEDGVQAQYDPNGKPERFYYNVESCGSLRPETIVMSALAMLKKKLSDLQTQL 259
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Zebrafish
Match: polr1c (RNA polymerase I and III subunit C [Source:ZFIN;Acc:ZDB-GENE-040426-1495])

HSP 1 Score: 64.3142 bits (155), Expect = 5.249e-11
Identity = 71/304 (23.36%), Postives = 123/304 (40.46%), Query Frame = 1 
Query:  127 VLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSD-----------------DIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLK---TSNPRVVPATFRIGE-DGDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYS----------------------------QLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSLE 891
            +++ +EN  EF    ++    ++AN+ RR   A+VPT+AI  V +  N++++ DE ++ R+GL+P+ +D                 D + +L    +C  +   P  S         +      + S D+K     N   V A  +IG   GD      IL+ ++R  Q L + +   K I KDH KF P ++  +   P+ +L   +  +  +  K  +S                             L+  + ++        + F F+VES G L P  +V  A+ VL  K       LE
Sbjct:   69 IISSDENTLEFDMIGID---AAIANAFRRILLAEVPTMAIEKVFIYNNTSIIQDEILAHRLGLVPIKADPRLFEYRNSEDQEGTEIDTI-QLQLKVKCTRNPRAPKDS-----SDPKELYLNHMIYSGDIKWLPIGNQADVFADAKIGPVHGD------ILLAQVRPGQELDIVMHCVKGIGKDHAKFSPVATASYRLLPEITLLQTIEGEQAERLKRCFSPGVIELENVNGRKVAKVVNSRLDTCSREVLRHDDLKSLVKLGRVRDHFIFSVESTGILPPDVLVTEAINVLMSKCQKFLTELE 357
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Zebrafish
Match: polr1c (RNA polymerase I and III subunit C [Source:ZFIN;Acc:ZDB-GENE-040426-1495])

HSP 1 Score: 51.9878 bits (123), Expect = 1.674e-7
Identity = 23/69 (33.33%), Postives = 45/69 (65.22%), Query Frame = 1 
Query:  127 VLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSD 333
            +++ +EN  EF    ++    ++AN+ RR   A+VPT+AI  V +  N++++ DE ++ R+GL+P+ +D
Sbjct:   69 IISSDENTLEFDMIGID---AAIANAFRRILLAEVPTMAIEKVFIYNNTSIIQDEILAHRLGLVPIKAD 134
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Xenopus
Match: ttll1 (tubulin tyrosine ligase like 1 [Source:Xenbase;Acc:XB-GENE-920807])

HSP 1 Score: 283.108 bits (723), Expect = 4.383e-94
Identity = 142/263 (53.99%), Postives = 191/263 (72.62%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGED--GDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            MPYANQ  + + E  DE +KF +E+T L++ANSIRR   A+VPTIAI WV +  NS++LHDEFI+ RVGLIPLTSDDIVD+L  + +C C +FCP+CS+E  LDV C+++  + VTS DL ++N RV+P T R  ++   D  EQ+ ILIVK+R+ Q L+LR  AKK   K+H K+ PT+ V FEYDPDN+LRH +  KPE+WPKSEYS++   E +AP++  G P +F++ VES GSL+P+ IVLSAL  LK+KL  +Q  L
Sbjct:    1 MPYANQPTVRITELTDENVKFIVENTDLAIANSIRRVFIAEVPTIAIDWVQIDANSSVLHDEFIAHRVGLIPLTSDDIVDKLQYSRDCTCDEFCPECSVEFTLDVRCNEDQTRHVTSRDLVSNNLRVIPVTSRSRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSEIDEEEAEAPYDPTGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQL 263
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Xenopus
Match: POLR1C (RNA polymerase I and III subunit C [Source:NCBI gene;Acc:100379802])

HSP 1 Score: 62.003 bits (149), Expect = 4.616e-10
Identity = 46/183 (25.14%), Postives = 87/183 (47.54%), Query Frame = 1 
Query:  160 IKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGEDGDLTEQEP-----------ILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSL 675
            ++F +     S+AN+ RR   A+VPT+A+  V+V  N++++ DE ++ R+GLIP+  D  +    S  E   ++       EL++    +    K  +  +    N +V  +  +    G+ ++  P           ILI ++R  Q + + +   K I KDH KF P ++  +   P+ +L
Sbjct:   61 LEFDMVGIDASIANAFRRILLAEVPTMAVEKVYVYNNTSIIQDEILAHRLGLIPIRVDPRLFEYRSAEEGEGTEI-DTLQFELNVKCTRNPRASKDCSDPNELYLNHKVYTSHMKWLPQGNQSDLFPETDPPRPVHGDILIAQLRPGQEISVIMHCVKGIGKDHAKFSPVATASYRLLPEITL 242
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Xenopus
Match: POLR1C (RNA polymerase I and III subunit C [Source:NCBI gene;Acc:100379802])

HSP 1 Score: 61.2326 bits (147), Expect = 6.273e-10
Identity = 46/183 (25.14%), Postives = 87/183 (47.54%), Query Frame = 1 
Query:  160 IKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGEDGDLTEQEP-----------ILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSL 675
            ++F +     S+AN+ RR   A+VPT+A+  V+V  N++++ DE ++ R+GLIP+  D  +    S  E   ++       EL++    +    K  +  +    N +V  +  +    G+ ++  P           ILI ++R  Q + + +   K I KDH KF P ++  +   P+ +L
Sbjct:   61 LEFDMVGIDASIANAFRRILLAEVPTMAVEKVYVYNNTSIIQDEILAHRLGLIPIRVDPRLFEYRSAEEGEGTEI-DTLQFELNVKCTRNPRASKDCSDPNELYLNHKVYTSHMKWLPQGNQSDLFPETDPPRPVHGDILIAQLRPGQEISVIMHCVKGIGKDHAKFSPVATASYRLLPEITL 242
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Mouse
Match: Polr2c (polymerase (RNA) II (DNA directed) polypeptide C [Source:MGI Symbol;Acc:MGI:109299])

HSP 1 Score: 282.337 bits (721), Expect = 6.880e-94
Identity = 142/263 (53.99%), Postives = 191/263 (72.62%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGED--GDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            MPYANQ  + + E  +E +KF +E+T L+VANSIRR   A+VP IAI WV +  NS++LHDEFI+ R+GLIPLTSDDIVD+L  + +C C +FCP+CS+E  LDV C+++  + VTS DL +++PRV+P T R  ++   D  EQ+ ILIVK+R+ Q L+LR  AKK   K+H K+ PT+ V FEYDPDN+LRH +  KPE+WPKSEYS+L   E QAP++  G P +F++ VES GSL+P+ IVLSAL  LK+KL  +Q  L
Sbjct:    1 MPYANQPTVRITELTEENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLTSDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQL 263
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Mouse
Match: Polr2c (polymerase (RNA) II (DNA directed) polypeptide C [Source:MGI Symbol;Acc:MGI:109299])

HSP 1 Score: 244.588 bits (623), Expect = 4.389e-77
Identity = 127/250 (50.80%), Postives = 172/250 (68.80%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGED--GDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALR 849
            MPYANQ  + + E  +E +KF +E+T L+VANSIRR   A+VP IAI WV +  NS++LHDEFI+ R+GLIPLTSDDIVD+L  + +C C +FCP+CS+E  LDV C+++  + VTS DL +++PRV+P T R  ++   D  EQ+ ILIVK+R+ Q L+LR  AKK   K+H K+ PT+ V FEYDPDN+LRH +  KPE+WPKSEYS+L   E QAP++  G P +        G L P+ + L   R
Sbjct:    1 MPYANQPTVRITELTEENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLTSDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERL-------GDLGPRPLTLGQPR 243
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Mouse
Match: Polr2c (polymerase (RNA) II (DNA directed) polypeptide C [Source:MGI Symbol;Acc:MGI:109299])

HSP 1 Score: 114.775 bits (286), Expect = 2.181e-30
Identity = 64/119 (53.78%), Postives = 88/119 (73.95%), Query Frame = 1 
Query:  187 LSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGED--GDLTEQE 537
            L+VANSIRR   A+VP IAI WV +  NS++LHDEFI+ R+GLIPLTSDDIVD+L  + +C C +FCP+CS+E  LDV C+++  + VTS DL +++PRV+P T R  ++   D  EQ+
Sbjct:    3 LAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLTSDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQD 121
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Mouse
Match: Polr2c (polymerase (RNA) II (DNA directed) polypeptide C [Source:MGI Symbol;Acc:MGI:109299])

HSP 1 Score: 112.464 bits (280), Expect = 4.998e-30
Identity = 58/114 (50.88%), Postives = 81/114 (71.05%), Query Frame = 1 
Query:  373 CSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGED--GDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDW 708
            C +FCP+CS+E  LDV C+++  + VTS DL +++PRV+P T R  ++   D  EQ+ ILIVK+R+ Q L+LR  AKK   K+H K+ PT+ V FEYDPDN+LRH +  KPE+W
Sbjct:    3 CEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEW 116
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Mouse
Match: Polr1c (polymerase (RNA) I polypeptide C [Source:MGI Symbol;Acc:MGI:103288])

HSP 1 Score: 59.6918 bits (143), Expect = 1.501e-9
Identity = 66/277 (23.83%), Postives = 114/277 (41.16%), Query Frame = 1 
Query:  160 IKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFR---IGEDGDLTEQ-------EPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQ-LKPG-----EHQ---------APFNTYG-----------------TPNKFFFTVESAGSLKPQNIVLSALRVLKEK 864
            ++F +     ++AN+ RR   A+VPT+A+  V V  N++++ DE ++ R+GLIP+ +D  +    +  E   ++        L +    +    K  +  +    N +V         +G   D+  +       + ILI ++R  Q + L +   K I KDH KF P ++  +   P  +    LL   E     E SQ   PG     E Q         A  +T+                    + + F+VES G L P  +V  A+++L  K
Sbjct:   61 LEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPILADPRLFEYRNQGEEEGTEI-DTLQFRLQVRCTRNPNAAKDSSDPNELYVNHKVYTRHMTWVPLGNQADVFPEGTIRPVHDDILIAQLRPGQEIDLMMHCVKGIGKDHAKFSPVATASYRLLPAIT----LLEPVEGEAAEELSQCFSPGVIEVEEVQGKKVARVANARLDTFSREIFRHEKLKKAVRLARVRDHYIFSVESTGVLPPDVLVSEAIKILMGK 332
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. UniProt/SwissProt
Match: sp|Q3T0Q3|RPB3_BOVIN (DNA-directed RNA polymerase II subunit RPB3 OS=Bos taurus OX=9913 GN=POLR2C PE=1 SV=1)

HSP 1 Score: 283.878 bits (725), Expect = 1.145e-93
Identity = 143/263 (54.37%), Postives = 191/263 (72.62%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGED--GDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            MPYANQ  + + E  DE +KF +E+T L+VANSIRR   A+VP IAI WV +  NS++LHDEFI+ R+GLIPLTSDDIVD+L  + +C C +FCP+CS+E  LDV C+++  + VTS DL +++PRV+P T R  ++   D  EQ+ ILIVK+R+ Q L+LR  AKK   K+H K+ PT+ V FEYDPDN+LRH +  KPE+WPKSEYS+L   E QAP++  G P +F++ VES GSL+P+ IVLSAL  LK+KL  +Q  L
Sbjct:    1 MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLTSDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQL 263
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. UniProt/SwissProt
Match: sp|P97760|RPB3_MOUSE (DNA-directed RNA polymerase II subunit RPB3 OS=Mus musculus OX=10090 GN=Polr2c PE=1 SV=2)

HSP 1 Score: 282.337 bits (721), Expect = 4.812e-93
Identity = 142/263 (53.99%), Postives = 191/263 (72.62%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGED--GDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            MPYANQ  + + E  +E +KF +E+T L+VANSIRR   A+VP IAI WV +  NS++LHDEFI+ R+GLIPLTSDDIVD+L  + +C C +FCP+CS+E  LDV C+++  + VTS DL +++PRV+P T R  ++   D  EQ+ ILIVK+R+ Q L+LR  AKK   K+H K+ PT+ V FEYDPDN+LRH +  KPE+WPKSEYS+L   E QAP++  G P +F++ VES GSL+P+ IVLSAL  LK+KL  +Q  L
Sbjct:    1 MPYANQPTVRITELTEENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLTSDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQL 263
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. UniProt/SwissProt
Match: sp|P19387|RPB3_HUMAN (DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2)

HSP 1 Score: 281.952 bits (720), Expect = 6.890e-93
Identity = 142/263 (53.99%), Postives = 190/263 (72.24%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGED--GDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            MPYANQ  + + E  DE +KF +E+T L+VANSIRR   A+VP IAI WV +  NS++LHDEFI+ R+GLIPL SDDIVD+L  + +C C +FCP+CS+E  LDV C+++  + VTS DL +++PRV+P T R  ++   D  EQ+ ILIVK+R+ Q L+LR  AKK   K+H K+ PT+ V FEYDPDN+LRH +  KPE+WPKSEYS+L   E QAP++  G P +F++ VES GSL+P+ IVLSAL  LK+KL  +Q  L
Sbjct:    1 MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQL 263
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. UniProt/SwissProt
Match: sp|P37382|RPB3_SCHPO (DNA-directed RNA polymerase II subunit RPB3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rpb3 PE=1 SV=2)

HSP 1 Score: 157.918 bits (398), Expect = 2.187e-44
Identity = 100/267 (37.45%), Postives = 150/267 (56.18%), Query Frame = 1 
Query:  124 SVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVD----RLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGED--GDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPED----WPKSEYSQL-KPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSLE 891
            ++ N+ +N    + F L +T L+VANS+RR   A++PT+AI  V +  N++++ DEF++ R+G+IPL S +I +     L     C C  +CP CS+EL L+  C  E    + + DL      VV +   +G     D   + P LI K+R+ Q + LR +AKK IAK+H K+ PTS+V FEYDP N L+H       D    WPKS+ +   +P     PFN    P +F+  VES GS+ P  I++  LR+L+EKL  +   L+
Sbjct:    8 TIRNISKNS---VDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLAHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYARDL------VVSSNSSLGHPILADPKSRGP-LICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFEYDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESVGSIPPNEIMVQGLRILQEKLAVLVRDLD 264
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. UniProt/SwissProt
Match: sp|Q54DH7|RPB3_DICDI (DNA-directed RNA polymerase II subunit rpb3 OS=Dictyostelium discoideum OX=44689 GN=polr2c PE=3 SV=1)

HSP 1 Score: 154.066 bits (388), Expect = 5.932e-43
Identity = 104/291 (35.74%), Postives = 161/291 (55.33%), Query Frame = 1 
Query:  121 QSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGEDGDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDP-----DNSLRHVLLAKPEDW----PKSEYSQ-----------------LKPGEHQAPFNTYGTP---------NKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            Q  L + E  ++ I F L +T +SVAN++RR   A+VPT+ I  V    N+++L DEFI+ R+GLIPL SD+I D+     +C CSD C  CS+EL L+V C +   + VTS+DL + N  V+P + ++      +EQE I IVK+RR Q +KLR +AKK + K+H K+ P+    +++ P      N +  +   + E+W    P   YS                  +   E +    ++G P         +KF FTVES+G+LKP++IVL A++++K KL  +Q  +
Sbjct:   11 QPELEILEIKNDSIIFILSNTDISVANALRRVMIAEVPTMCIDLVEFESNNSVLCDEFIAHRLGLIPLVSDNI-DKFCYTRDCSCSDRCDQCSVELRLNVKCTENRPRDVTSSDLLSQNSAVIPVSSQVTSSN--SEQE-IPIVKLRRGQEIKLRAIAKKGVGKEHAKWSPSCVATYQFQPIIVLNQNRIDELTDQQKEEWVGSCPTKVYSYSPHQSTQQVTIEDPLRCVYCLECKKKAESFGKPDLVHLEQKQDKFIFTVESSGALKPEDIVLYAIQIIKRKLTDIQGQM 297
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. TrEMBL
Match: A0A0X3Q8W5 (DNA-directed RNA polymerase II subunit RPB3 OS=Schistocephalus solidus OX=70667 GN=RPB3 PE=4 SV=1)

HSP 1 Score: 308.531 bits (789), Expect = 5.772e-101
Identity = 157/261 (60.15%), Postives = 195/261 (74.71%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGEDGDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            MPYANQSV+ V    DE  KFTLEDT LSVAN+IRR C A+VPT+AI WV + EN+TML+DEFI+QRVGLIPLTSD++VD++    EC C DFC DCS+EL LDV C D+  + VT ADL +SN  V P   R  +D     QE ILIVK+R+ QRLKLR  AKK   K+H K+ PT+ V FEYDPDN+LRH  L KPE+WP+SEYS+L+P + QAP++ +G P+KF+ TVES GSLK +NI+ SALRVLKEKL  + ++L
Sbjct:    1 MPYANQSVVTVISFNDEVFKFTLEDTDLSVANAIRRVCIAEVPTLAIDWVQLEENNTMLNDEFIAQRVGLIPLTSDEVVDKMTYFRECTCRDFCKDCSVELTLDVACTDDTPRHVTGADLVSSNRDVRPVPCRETDDALYGAQESILIVKMRKGQRLKLRAFAKKGFGKEHAKWNPTAGVGFEYDPDNALRHTFLQKPEEWPRSEYSELEPDQSQAPYDPFGKPSKFYITVESCGSLKAKNIIFSALRVLKEKLTTLHDNL 261
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. TrEMBL
Match: A0A0R3U2Z3 (RPOLD domain-containing protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS887 PE=4 SV=1)

HSP 1 Score: 303.908 bits (777), Expect = 3.265e-99
Identity = 156/264 (59.09%), Postives = 194/264 (73.48%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGEDGD---LTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            MPYANQS++ V    DE  KF LEDT LSVAN+IRR C A+VPT+AI WV + EN+TML+DEFI+QRVGLIPLTSD++VD++    EC C DFC +CS+EL LDV C D+  + VT ADL+TSN  V P   R   D       +QE ILIVK+R+ QRLKLR  AKK   K+H K+ PT+ V FEYDPDN+LRH  + KPEDWP+SEYS+LK  + QAP++ +G P+KF+FTVES GSLK +NI+ SALRVLKEKL  +  +L
Sbjct:    1 MPYANQSIVTVISFNDEVFKFALEDTDLSVANAIRRVCIAEVPTLAIDWVQLEENNTMLNDEFIAQRVGLIPLTSDNVVDKMSYFRECTCRDFCKECSVELTLDVSCTDDTPRHVTGADLQTSNHEVRPVPNRDENDDSSLYAGQQESILIVKMRKGQRLKLRAFAKKGFGKEHAKWSPTAGVGFEYDPDNALRHTFIQKPEDWPRSEYSELKDDQFQAPYDPFGKPSKFYFTVESCGSLKAKNIIFSALRVLKEKLTTLHENL 264
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. TrEMBL
Match: A0A087W4V9 (DNA directed RNA polymerase II subunit RPB3 OS=Echinococcus multilocularis OX=6211 PE=4 SV=1)

HSP 1 Score: 302.368 bits (773), Expect = 1.378e-98
Identity = 157/266 (59.02%), Postives = 194/266 (72.93%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGEDGD---LTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPG--EHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            MPYANQS++ V    DE  KF+LEDT LSVAN+IRR C A+VPT+AI WV + EN+TML+DEFI+QR+GLIPLTSDD+VD++    EC C DFC +CS+EL LDV C D+  + VT ADL TSNP V P   R   D       +QE ILIVK+R+ QRLKLR  AKK   K+H K+ PT+ V FEYDPDN+LRH  L KPEDWP+SEYS+L     + QAP+N +G P+KF+FT+ES GSLK +NI+ SALRVLKEKL  +  +L
Sbjct:    1 MPYANQSIVTVTSYNDEVFKFSLEDTDLSVANAIRRVCIAEVPTLAIDWVQLEENNTMLNDEFIAQRIGLIPLTSDDVVDKMSYFRECTCRDFCKECSVELTLDVSCTDDAPRHVTGADLVTSNPDVRPVPCRDENDESALYAGQQESILIVKMRKGQRLKLRAFAKKGFGKEHAKWNPTAGVGFEYDPDNALRHTFLQKPEDWPRSEYSELPADSEQSQAPYNPFGKPSKFYFTIESCGSLKAKNIIFSALRVLKEKLTTLHENL 266
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. TrEMBL
Match: U6JIB6 (DNA-directed RNA polymerase II subunit rpb3 OS=Echinococcus granulosus OX=6210 GN=EGR_08766 PE=4 SV=1)

HSP 1 Score: 302.368 bits (773), Expect = 1.440e-98
Identity = 157/266 (59.02%), Postives = 194/266 (72.93%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGEDGD---LTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPG--EHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            MPYANQS++ V    DE  KF+LEDT LSVAN+IRR C A+VPT+AI WV + EN+TML+DEFI+QR+GLIPLTSDD+VD++    EC C DFC +CS+EL LDV C D+  + VT ADL TSNP V P   R   D       +QE ILIVK+R+ QRLKLR  AKK   K+H K+ PT+ V FEYDPDN+LRH  L KPEDWP+SEYS+L     + QAP+N +G P+KF+FT+ES GSLK +NI+ SALRVLKEKL  +  +L
Sbjct:    1 MPYANQSIVTVTSYNDEVFKFSLEDTDLSVANAIRRVCIAEVPTLAIDWVQLEENNTMLNDEFIAQRIGLIPLTSDDVVDKMSYFRECTCRDFCKECSVELTLDVSCTDDTPRHVTGADLVTSNPDVRPVPCRDENDESALYAGQQESILIVKMRKGQRLKLRAFAKKGFGKEHAKWNPTAGVGFEYDPDNALRHTFLQKPEDWPRSEYSELPADSEQSQAPYNPFGKPSKFYFTIESCGSLKAKNIIFSALRVLKEKLTTLHENL 266
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. TrEMBL
Match: A0A1S3J1Y3 (DNA-directed RNA polymerase II subunit RPB3 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106169073 PE=4 SV=1)

HSP 1 Score: 297.745 bits (761), Expect = 1.055e-96
Identity = 148/261 (56.70%), Postives = 190/261 (72.80%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGEDGDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            MPYANQ  ++V E  DE IKF LEDT LS AN++RR   A+VPT+AI WV +  NS++LHDEFI+ RVGLIPLTSD++VDR+  + +C C +FCP+CS+E  L+V C D+  + VT+AD+ +SNP+VVP T +  E+    E + ILIVK+R+ Q LKLR  A+K  AK+H K+ PTS V FEYDPDN+LRH    KPE+WPKSEYS+L   E +AP++  G PNKFFF VES G+LKP+NIV S L VLK KL  +Q  L
Sbjct:    1 MPYANQPTIHVSELTDENIKFVLEDTDLSTANAMRRVVIAEVPTLAIDWVQIEANSSVLHDEFIAHRVGLIPLTSDEVVDRMQYSRDCTCDEFCPECSVEFQLEVKCTDDQTRHVTTADMISSNPKVVPVTSKHREEEGYGETDDILIVKLRKGQELKLRAFARKGFAKEHAKWNPTSGVAFEYDPDNALRHTDYPKPEEWPKSEYSELPDDEFEAPYDMSGKPNKFFFNVESCGALKPENIVFSGLSVLKNKLSNLQTQL 261
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Cavefish
Match: polr2c (RNA polymerase II subunit C [Source:NCBI gene;Acc:103042586])

HSP 1 Score: 273.478 bits (698), Expect = 1.597e-90
Identity = 142/263 (53.99%), Postives = 193/263 (73.38%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGED--GDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            MPYANQ  + + E  DE +KF +E+T L+VANSIRR   ++V TIAI W+ +  NS++LHDEFI+ RVGLIPLTSDDIVD++  + +C C DFCP+CS+EL LDV C ++  + VTS DL ++NPRV+P T R  ++   D  EQ+ IL+VK+R+ Q L+LR  AKK   K+H K+ PT+ V FEYDPDN+LRH +  +PE+WPKSEYS+++  E QAP++  G P +F+F VES GSL+P+ IV+SAL VLK+KL  +Q  L
Sbjct:    1 MPYANQPTVKITELSDENVKFVIENTDLAVANSIRRVFMSEVATIAIDWIQIDANSSVLHDEFIAHRVGLIPLTSDDIVDKMQYSRDCTCDDFCPECSVELTLDVRCTEDQTRHVTSRDLLSNNPRVIPVTSRSRDNDPNDYVEQDDILLVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPRPEEWPKSEYSEIEEEEVQAPYDPNGKPERFYFNVESCGSLRPETIVMSALAVLKKKLSDLQTQL 263
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Cavefish
Match: polr1c (RNA polymerase I and III subunit C [Source:NCBI gene;Acc:103038473])

HSP 1 Score: 64.3142 bits (155), Expect = 4.534e-11
Identity = 69/298 (23.15%), Postives = 123/298 (41.28%), Query Frame = 1 
Query:  130 LNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLK---------TSNPRVVPATFRIGEDGDLTE-------QEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQ----------------------------LKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSLE 891
            LN+    +  ++F +     ++AN+ RR   A+VPT+AI  V +  N++++ DE ++ R+GL+P+ +D    RL         +     +I+L L + C    + +  S+D K         + +   VP    IG   D+          + IL+ ++R  Q L + +   K I KDH KF P ++  +   P+ +L   +  +  +  K  +S                             L+  + +         + F F+VES G L P+ +V  A+ VL  K       LE
Sbjct:   53 LNIAHMDENTLEFDMVGIDAAIANAFRRILLAEVPTMAIEKVFIYNNTSIIQDEILAHRLGLVPIKAD---PRLFEYRNAGDEEGTEIDTIQLQLKIKCTRNTRAAKDSSDPKELYLNHMVYSKDITWVP----IGNQADVFGDSKIGPVHDDILLAQLRPGQELDIVMHCVKGIGKDHAKFSPVATASYRLLPEITLLQTVEGEKAERLKRCFSAGVIEVENINGEQVAKVVNSRLDTCSREVLRHDDLKNLVKIGRVRDHFIFSVESTGILPPEVLVSEAINVLIAKCQKFLTELE 343
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Cavefish
Match: polr1c (RNA polymerase I and III subunit C [Source:NCBI gene;Acc:103038473])

HSP 1 Score: 52.7582 bits (125), Expect = 1.916e-7
Identity = 22/68 (32.35%), Postives = 43/68 (63.24%), Query Frame = 1 
Query:  130 LNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSD 333
            LN+    +  ++F +     ++AN+ RR   A+VPT+AI  V +  N++++ DE ++ R+GL+P+ +D
Sbjct:   52 LNIAHMDENTLEFDMVGIDAAIANAFRRILLAEVPTMAIEKVFIYNNTSIIQDEILAHRLGLVPIKAD 119
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Sea Lamprey
Match: polr2c (polymerase (RNA) II (DNA directed) polypeptide C [Source:ZFIN;Acc:ZDB-GENE-030131-6609])

HSP 1 Score: 254.218 bits (648), Expect = 2.608e-84
Identity = 128/228 (56.14%), Postives = 168/228 (73.68%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGED--GDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNK 783
            MPYANQ  + + E  DE +KF +EDT L+VANS+RRT  A+VPT+AI WV +  NS++LHDEFI+ RVGLIPLTSD+IVD++  + +C C +FC +CS+EL+L+V C ++  + VTS DL ++NPRVV  T R  ED   D  EQ+ ILIVK+R+ Q LKLR  AKK   K+H K+ PT+ V FEYDPDN+LRH +  KPE+WPKSEYS+L+  E QAPF+  G PN+
Sbjct:    1 MPYANQPTVKISELTDENVKFIVEDTDLAVANSLRRTFHAEVPTLAIDWVQIDANSSVLHDEFIAHRVGLIPLTSDEIVDKMQYSRDCTCDEFCAECSVELNLEVKCSEDQTRHVTSRDLISTNPRVVQVTSRSREDDPNDYGEQDDILIVKLRKGQELKLRAHAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTIFPKPEEWPKSEYSELEEDEIQAPFDPNGVPNR 228
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Sea Lamprey
Match: polr1c (RNA polymerase I and III subunit C [Source:ZFIN;Acc:ZDB-GENE-040426-1495])

HSP 1 Score: 63.1586 bits (152), Expect = 2.072e-11
Identity = 65/288 (22.57%), Postives = 120/288 (41.67%), Query Frame = 1 
Query:  151 DEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFR---IGEDGDLTEQ-------EPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQ--------------APFNTYGTP-----------------NKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSLE 891
            D  ++F +     ++AN+ RR   A+VPT+A+  V +  N++++ DE ++ R+GLIP+ +D  +    +  +   +D       +L +    + +  K  +  +    N +V     R   +G   D+  +       + ILI  +R    + + V   K I +DH KF P ++  +   P+  L   ++       +S +S+   G  +              A  +T                     N F F+VES G+L P  +V  A++VL EK     N L+
Sbjct:   59 DMEMEFDMVGVDAAIANAFRRILLAEVPTMAVEKVFIYNNTSIIQDEILAHRLGLIPIHADPRLFEFRNPGDEEGTDI-DTVQFQLKVKCSRNPKAPKDSSDPNELYINHKVYSRHLRWVPLGSQADVYAEGSIRPVNDDILIALLRPGHEIDIMVHCVKGIGRDHAKFSPVATASYRLLPEIRLLVPVVGALALKLQSCFSEGVIGVEEVDACAGEKVAKVLNARLDTCSREVLRHEDLKDLVQLCRIRNHFIFSVESTGALPPSVLVCEAIKVLMEKCRKYLNELD 345
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Yeast
Match: RPB3 (RNA polymerase II third largest subunit B44; part of central core; similar to prokaryotic alpha subunit [Source:SGD;Acc:S000001283])

HSP 1 Score: 147.902 bits (372), Expect = 3.846e-42
Identity = 92/255 (36.08%), Postives = 142/255 (55.69%), Query Frame = 1 
Query:  130 LNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLK-TSNPRVVPATFRIGEDGDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPED----WPKSEYSQLK-PGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAV 876
            + + E   + + F L +  L++ANS+RR   A++PT+AI  V V  N+T+L DEFI+ R+GLIPL S DI ++L  + +C C D C  CS+ L L    + E   +V S DL   SN         I +D    E   +LI K+R+ Q LKL  +AKK IAK+H K+ P +++ FEYDP N L+H      +D    WP+S+  + + P     PF+     + F+  VES GS+    +V+  +  L++K+ ++
Sbjct:    8 VKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDI-EQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQD---KEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASI 258
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Yeast
Match: RPC40 (RNA polymerase subunit AC40; common to RNA polymerase I and III; predominant determinant targeting Ty1 integration upstream of Pol III-transcribed genes [Source:SGD;Acc:S000006314])

HSP 1 Score: 69.707 bits (169), Expect = 7.641e-14
Identity = 71/277 (25.63%), Postives = 115/277 (41.52%), Query Frame = 1 
Query:  166 FTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKT--SNPRVVPATFRIGEDGD---------LTEQEP-ILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPD---------NSLRHVLLAKP---------------EDWPKSEYSQ--LKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQN 882
            F L +   S+AN+ RR   ++VP++A  +V+   N++++ DE ++ R+GL+PL  D  +   V ++      F  + +I L L+V C         S D K   +N  V     +    G          +   +P IL+ K+R  Q + L+      I  DH KF P S+  +   P           S R      P               +D  K   S+  L+  E           N F F VESAG++ P+ I   ++R+LK K   ++N
Sbjct:   54 FDLINIDTSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVLAHRIGLVPLKVDPDMLTWVDSNLPDDEKFTDENTIVLSLNVKCTRNPDAPKGSTDPKELYNNAHVYARDLKFEPQGRQSTTFADCPVVPADPDILLAKLRPGQEISLKAHCILGIGGDHAKFSPVSTASYRLLPQINILQPIKGESARRFQKCFPPGVIGIDEGSDEAYVKDARKDTVSREVLRYEEFADKVKLGRVRNHFIFNVESAGAMTPEEIFFKSVRILKNKAEYLKN 330
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Nematostella
Match: EDO36595 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI64])

HSP 1 Score: 276.174 bits (705), Expect = 4.888e-92
Identity = 141/266 (53.01%), Postives = 189/266 (71.05%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGEDG--DLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKL--LAVQNSLE 891
            MPYANQ  + + E  DE +KF +E T +S+AN +RR   A+ PTIAI WV +  N+++LHDEFI+ R+GL+PLTSD++VDR+  + +C C +FC DCSIE  LDV C D+  + VT+ DL ++NPR VP T R  ED   +  EQ+ ILIVK+R+ Q LKLR  AKK  AK+H K+ PT+ V FEYDPDN+LRH    +PE+WPKSEY++L+  ++QAPF+     +KF+  VES GSLKP+NIVLS L +LK+KL  L  Q+S E
Sbjct:    1 MPYANQPSVKILELTDENVKFIIEKTGMSMANGLRRIFIAETPTIAIDWVQIENNTSVLHDEFIAHRLGLVPLTSDEVVDRMTFSRDCTCDEFCDDCSIEFTLDVKCTDDSTRHVTTQDLISTNPRCVPVTSRNREDDSREYMEQDDILIVKLRKGQELKLRAFAKKGFAKEHAKWNPTAGVAFEYDPDNALRHTTYPRPEEWPKSEYTELEEDQYQAPFDPNAKADKFYINVESCGSLKPENIVLSGLAILKKKLSDLQTQHSHE 266
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Nematostella
Match: EDO35589 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SL38])

HSP 1 Score: 51.9878 bits (123), Expect = 1.577e-7
Identity = 69/277 (24.91%), Postives = 112/277 (40.43%), Query Frame = 1 
Query:  160 IKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQ--KSVTSADLKTSNPRV-------VPATFRIGEDGDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKP-EDWPKSEYSQ-LKPG-------------------------------EHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEK 864
            ++F +     SVAN+ RR   A+VPT+AI  V +  N++++ DE ++ R+GLIP+ +D    RL +  +    +   D ++  +L V C       K  T  D    N +V       +P   +  + G    +    +V     Q L +++ A K + KDH KF P       Y     L  + L KP ED    + +    PG                                     N +   N    +VES G+L+P+ +V  A++VL  K
Sbjct:   58 MEFDMIGIDASVANAFRRILLAEVPTMAIEKVFLYNNTSIIQDEVLAHRLGLIPIHAD---PRLFNYKKQGDEEAQDDTTLVFELKVKCIKNKNAPKDATDPDELYINSKVTTDHLKWIPTPQQAQKFGPQDIRPLSNVVFFFTLQELDIKMHAVKGVGKDHAKFSPVGKSTASY---RLLPEITLLKPCEDELADKLAACFSPGVIKVKTVNEKNHTNDQNVGLRSLCNIISVYISENIIRNEFVEKNYTNVSVESIGALRPEVLVCEAIKVLISK 328
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Medaka
Match: polr2c (RNA polymerase II subunit C [Source:NCBI gene;Acc:101167955])

HSP 1 Score: 289.656 bits (740), Expect = 6.670e-97
Identity = 141/263 (53.61%), Postives = 194/263 (73.76%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGED--GDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            MPYANQ  + + E  DE +KF +E+T L+VANSIRR   ++VPTIAI W+ +  NS++LHDEFI+ RVGLIPLTSDDIVD++  + +C C DFCP+CS+EL LDV C ++  + VTS DL ++NPRV+P T R  ++   D  EQ+ IL+VK+R+ Q L+LR  AKK   K+H K+ PT+ V FEYDPDN+LRH +  +PE+WPKSEYS+++  E QAP++  G P +F++ VES GSL+P+ +V+SAL VLK+KL  +Q  L
Sbjct:    1 MPYANQPTVKITELTDENVKFVIENTDLAVANSIRRVFMSEVPTIAIDWIQIDANSSVLHDEFIAHRVGLIPLTSDDIVDKMQYSRDCTCEDFCPECSVELTLDVRCTEDQTRHVTSRDLLSNNPRVIPVTSRSRDNDPNDYVEQDDILLVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVSFEYDPDNALRHTVYPRPEEWPKSEYSEIEEDEVQAPYDPNGKPERFYYNVESCGSLRPETVVMSALAVLKKKLSDLQTQL 263
[Close]
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Medaka
Match: polr1c (RNA polymerase I and III subunit C [Source:NCBI gene;Acc:101171140])

HSP 1 Score: 67.0106 bits (162), Expect = 4.524e-12
Identity = 72/298 (24.16%), Postives = 124/298 (41.61%), Query Frame = 1 
Query:  127 VLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSD-------------DIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLK---TSNPRVVPATFRIGEDGDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQ----------------------------LKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            V++++EN    I+F +     ++AN+ RR   A+VPT+AI  V +  N++++ DE ++ R+GL+P+ +D               +D +    +  CS   P  S   +     +      V S D+      N   V A  RIG   D      I+I ++R  Q L + +   K I KDH KF P ++  +   PD +L   +  +  +  K  +S+                            L+  + +         + F FT+ES GSL    ++  A++VL  K   + N L
Sbjct:   51 VVHLDENN---IEFDMVGIDAAIANAFRRILLAEVPTMAIEKVFIYNNTSIVQDEVLAHRLGLVPIKADPRLFEYKNIEQEASEIDTIQLQLKIKCSR-NPRAS--KESSDPRELYLNHIVYSKDINWVPLGNQADVFADSRIGAVHD-----DIVIAQLRPGQELDVVMHCVKGIGKDHAKFSPVATASYRLLPDITLMEQVEGEKAERLKRCFSRGVIDLEDVRGKKVAKVVNSRLDTCSREVLRHKDLKNLVKLGRVRDHFIFTIESTGSLPADVLMQEAIKVLMAKCQMLLNEL 337
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BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Medaka
Match: polr1c (RNA polymerase I and III subunit C [Source:NCBI gene;Acc:101171140])

HSP 1 Score: 65.0846 bits (157), Expect = 1.954e-11
Identity = 72/303 (23.76%), Postives = 124/303 (40.92%), Query Frame = 1 
Query:  127 VLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSD------------------DIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLK---TSNPRVVPATFRIGEDGDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQ----------------------------LKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSL 888
            V++++EN    I+F +     ++AN+ RR   A+VPT+AI  V +  N++++ DE ++ R+GL+P+ +D                    +D +    +  CS   P  S   +     +      V S D+      N   V A  RIG   D      I+I ++R  Q L + +   K I KDH KF P ++  +   PD +L   +  +  +  K  +S+                            L+  + +         + F FT+ES GSL    ++  A++VL  K   + N L
Sbjct:   54 VVHLDENN---IEFDMVGIDAAIANAFRRILLAEVPTMAIEKVFIYNNTSIVQDEVLAHRLGLVPIKADPRLFEYKNIAEEFGEQEASEIDTIQLQLKIKCSR-NPRAS--KESSDPRELYLNHIVYSKDINWVPLGNQADVFADSRIGAVHD-----DIVIAQLRPGQELDVVMHCVKGIGKDHAKFSPVATASYRLLPDITLMEQVEGEKAERLKRCFSRGVIDLEDVRGKKVAKVVNSRLDTCSREVLRHKDLKNLVKLGRVRDHFIFTIESTGSLPADVLMQEAIKVLMAKCQMLLNEL 345
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BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Planmine SMEST
Match: SMESG000065615.1 (SMESG000065615.1)

HSP 1 Score: 513.072 bits (1320), Expect = 0.000e+0
Identity = 262/262 (100.00%), Postives = 262/262 (100.00%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGEDGDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSLE 891
            MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIELDLDVDCDDEDQKSVTSADLKTSNPRVVPATFRIGEDGDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSLE
Sbjct:    1 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIELDLDVDCDDEDQKSVTSADLKTSNPRVVPATFRIGEDGDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSLE 262
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BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Planmine SMEST
Match: SMESG000007495.1 (SMESG000007495.1)

HSP 1 Score: 426.787 bits (1096), Expect = 2.914e-151
Identity = 212/262 (80.92%), Postives = 236/262 (90.08%), Query Frame = 1 
Query:  106 MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWVHVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIXXXXXXXXXXXXQKSVTSADLKTSNPRVVPATFRIGEDGDLTEQEPILIVKIRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPEDWPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVLKEKLLAVQNSLE 891
            MPYANQSVLN+  N +E +KFTLEDTHLSVAN+IRRTCQADVPTIAI WV + ENSTMLHDEFI+QRVGLIPLTSDDIVDRL+   +C C+DFCPDC++E DLDV+C+DEDQ++VTSADLKTSNPRVVPAT R G+D D +EQEPILIVKIRR QRLKLR MAKK  AK+HVK+CPTSSV FEYDPDNSLRHVLLA+PEDWPKSEYSQLK GEHQAPFN YGTP+KF+ TVES GSLKPQNIVLSAL+VLKEKL AVQN+LE
Sbjct:    1 MPYANQSVLNITTNSEELLKFTLEDTHLSVANAIRRTCQADVPTIAIDWVQIEENSTMLHDEFIAQRVGLIPLTSDDIVDRLIYYRQCTCTDFCPDCTVEFDLDVECEDEDQRAVTSADLKTSNPRVVPATSRSGDDVDFSEQEPILIVKIRRGQRLKLRAMAKKGFAKEHVKWCPTSSVAFEYDPDNSLRHVLLARPEDWPKSEYSQLKAGEHQAPFNPYGTPSKFYLTVESTGSLKPQNIVLSALKVLKEKLQAVQNALE 262
The following BLAST results are available for this feature:
BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
POLR2C1.435e-9353.99RNA polymerase II subunit C [Source:HGNC Symbol;Ac... [more]
POLR1C3.015e-1025.17RNA polymerase I and III subunit C [Source:HGNC Sy... [more]
POLR1C4.578e-1026.63RNA polymerase I and III subunit C [Source:HGNC Sy... [more]
POLR1C4.578e-1026.63RNA polymerase I and III subunit C [Source:HGNC Sy... [more]
POLR1C6.476e-1027.14RNA polymerase I and III subunit C [Source:HGNC Sy... [more]
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BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
rpb-31.906e-6743.84RNA Polymerase II (B) subunit [Source:UniProtKB/T... [more]
rpac-401.370e-1120.86RNA Polymerase I/III (A/C) shared subunit [Source... [more]
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BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
RpII334.763e-9353.79gene:FBgn0026373 transcript:FBtr0080544[more]
CG37561.782e-1723.97gene:FBgn0031657 transcript:FBtr0078994[more]
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BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
polr2c5.551e-9352.47polymerase (RNA) II (DNA directed) polypeptide C [... [more]
polr2c5.051e-8349.62polymerase (RNA) II (DNA directed) polypeptide C [... [more]
polr2c5.051e-8349.62polymerase (RNA) II (DNA directed) polypeptide C [... [more]
polr1c5.249e-1123.36RNA polymerase I and III subunit C [Source:ZFIN;Ac... [more]
polr1c1.674e-733.33RNA polymerase I and III subunit C [Source:ZFIN;Ac... [more]
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BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ttll14.383e-9453.99tubulin tyrosine ligase like 1 [Source:Xenbase;Acc... [more]
POLR1C4.616e-1025.14RNA polymerase I and III subunit C [Source:NCBI ge... [more]
POLR1C6.273e-1025.14RNA polymerase I and III subunit C [Source:NCBI ge... [more]
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BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Polr2c6.880e-9453.99polymerase (RNA) II (DNA directed) polypeptide C [... [more]
Polr2c4.389e-7750.80polymerase (RNA) II (DNA directed) polypeptide C [... [more]
Polr2c2.181e-3053.78polymerase (RNA) II (DNA directed) polypeptide C [... [more]
Polr2c4.998e-3050.88polymerase (RNA) II (DNA directed) polypeptide C [... [more]
Polr1c1.501e-923.83polymerase (RNA) I polypeptide C [Source:MGI Symbo... [more]
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BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q3T0Q3|RPB3_BOVIN1.145e-9354.37DNA-directed RNA polymerase II subunit RPB3 OS=Bos... [more]
sp|P97760|RPB3_MOUSE4.812e-9353.99DNA-directed RNA polymerase II subunit RPB3 OS=Mus... [more]
sp|P19387|RPB3_HUMAN6.890e-9353.99DNA-directed RNA polymerase II subunit RPB3 OS=Hom... [more]
sp|P37382|RPB3_SCHPO2.187e-4437.45DNA-directed RNA polymerase II subunit RPB3 OS=Sch... [more]
sp|Q54DH7|RPB3_DICDI5.932e-4335.74DNA-directed RNA polymerase II subunit rpb3 OS=Dic... [more]
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BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0X3Q8W55.772e-10160.15DNA-directed RNA polymerase II subunit RPB3 OS=Sch... [more]
A0A0R3U2Z33.265e-9959.09RPOLD domain-containing protein OS=Mesocestoides c... [more]
A0A087W4V91.378e-9859.02DNA directed RNA polymerase II subunit RPB3 OS=Ech... [more]
U6JIB61.440e-9859.02DNA-directed RNA polymerase II subunit rpb3 OS=Ech... [more]
A0A1S3J1Y31.055e-9656.70DNA-directed RNA polymerase II subunit RPB3 isofor... [more]
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BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
polr2c1.597e-9053.99RNA polymerase II subunit C [Source:NCBI gene;Acc:... [more]
polr1c4.534e-1123.15RNA polymerase I and III subunit C [Source:NCBI ge... [more]
polr1c1.916e-732.35RNA polymerase I and III subunit C [Source:NCBI ge... [more]
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BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
polr2c2.608e-8456.14polymerase (RNA) II (DNA directed) polypeptide C [... [more]
polr1c2.072e-1122.57RNA polymerase I and III subunit C [Source:ZFIN;Ac... [more]
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BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
RPB33.846e-4236.08RNA polymerase II third largest subunit B44; part ... [more]
RPC407.641e-1425.63RNA polymerase subunit AC40; common to RNA polymer... [more]
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BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO365954.888e-9253.01Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO355891.577e-724.91Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
polr2c6.670e-9753.61RNA polymerase II subunit C [Source:NCBI gene;Acc:... [more]
polr1c4.524e-1224.16RNA polymerase I and III subunit C [Source:NCBI ge... [more]
polr1c1.954e-1123.76RNA polymerase I and III subunit C [Source:NCBI ge... [more]
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BLAST of DNA-directed RNA polymerase II subunit RPB3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000065615.10.000e+0100.00SMESG000065615.1[more]
SMESG000007495.12.914e-15180.92SMESG000007495.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011039 ID=SMED30011039|Name=DNA-directed RNA polymerase II subunit RPB3|organism=Schmidtea mediterranea sexual|type=transcript|length=1074bp
AATGCTATCATGCACATTTATAGCGCCTATTTTAAAACACGAATAAAACA
TTTAAAATAATTTGTTTAAAAATGCTCACTAAAATGAGTTTTATTATTAT
CCAATATGCCTTATGCAAATCAAAGTGTTTTAAATGTTGAAGAAAATTGT
GATGAATTCATTAAGTTTACATTGGAAGATACTCATCTCAGTGTTGCGAA
TTCAATCAGAAGGACATGTCAAGCTGATGTGCCCACCATAGCTATTGGTT
GGGTTCATGTTATAGAAAATTCAACTATGTTGCACGATGAATTTATTTCA
CAAAGAGTTGGATTGATTCCTTTGACATCAGATGACATTGTTGACCGTCT
AGTTAGCAATTCCGAATGTCCTTGCAGTGACTTCTGCCCCGATTGCTCAA
TAGAACTTGACTTAGATGTTGACTGTGACGATGAAGATCAAAAATCTGTT
ACAAGTGCTGATTTAAAAACCAGCAACCCTCGAGTGGTGCCTGCCACTTT
TCGTATTGGTGAAGATGGGGATTTAACGGAACAAGAGCCAATTCTTATTG
TGAAAATTCGTCGTAACCAGCGTTTGAAATTGAGAGTAATGGCTAAAAAA
AGCATAGCTAAAGACCATGTAAAATTTTGTCCAACTAGTAGCGTTCGTTT
TGAATATGATCCCGACAATTCTCTTCGACATGTTCTGTTAGCAAAACCTG
AAGATTGGCCGAAGTCAGAATATTCCCAATTAAAACCCGGTGAACATCAA
GCCCCGTTTAATACATACGGAACTCCAAATAAATTCTTTTTCACTGTTGA
ATCGGCAGGCTCATTAAAACCTCAAAATATTGTATTAAGTGCGTTGAGAG
TCCTTAAAGAAAAATTACTAGCGGTGCAGAACAGTTTGGAATAAAGCTTT
ATTTAATACATATTATGAAGCTCAAATCCCAGATTTTATTAGACAACATT
TCTATAAATATTTAATGAATCAAAAATATTCTTATTTTTGATATACCACG
ACTTCATTGGATTTGTATTAATTTTTAATGGTTTTCGTTAAGATTTTTTA
AATATATTTTGTCATATTGCAGTA
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protein sequence of SMED30011039-orf-1

>SMED30011039-orf-1 ID=SMED30011039-orf-1|Name=SMED30011039-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=263bp
MPYANQSVLNVEENCDEFIKFTLEDTHLSVANSIRRTCQADVPTIAIGWV
HVIENSTMLHDEFISQRVGLIPLTSDDIVDRLVSNSECPCSDFCPDCSIE
LDLDVDCDDEDQKSVTSADLKTSNPRVVPATFRIGEDGDLTEQEPILIVK
IRRNQRLKLRVMAKKSIAKDHVKFCPTSSVRFEYDPDNSLRHVLLAKPED
WPKSEYSQLKPGEHQAPFNTYGTPNKFFFTVESAGSLKPQNIVLSALRVL
KEKLLAVQNSLE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000419prepharyngeal region
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR036643RNApol_insert_sf
IPR036603RBP11-like
IPR011263DNA-dir_RNA_pol_RpoA/D/Rpb3
IPR011262DNA-dir_RNA_pol_insert
IPR009025RBP11-like_dimer
Vocabulary: molecular function
TermDefinition
GO:0003899DNA-directed 5'-3' RNA polymerase activity
GO:0046983protein dimerization activity
Vocabulary: biological process
TermDefinition
GO:0006351transcription, DNA-templated
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR011263DNA-directed RNA polymerase, RpoA/D/Rpb3-typeSMARTSM00662rpoldneu2coord: 18..260
e-value: 9.1E-58
score: 207.9
IPR011263DNA-directed RNA polymerase, RpoA/D/Rpb3-typePFAMPF01193RNA_pol_Lcoord: 20..254
e-value: 9.9E-16
score: 59.2
IPR036643DNA-directed RNA polymerase, insert domain superfamilyGENE3DG3DSA:2.170.120.12coord: 44..172
e-value: 4.3E-93
score: 313.1
IPR036643DNA-directed RNA polymerase, insert domain superfamilySUPERFAMILYSSF56553Insert subdomain of RNA polymerase alpha subunitcoord: 43..176
IPR011262DNA-directed RNA polymerase, insert domainPFAMPF01000RNA_pol_A_baccoord: 50..174
e-value: 4.1E-25
score: 88.3
IPR036603RNA polymerase, RBP11-like subunitGENE3DG3DSA:3.30.1360.10coord: 10..257
e-value: 4.3E-93
score: 313.1
IPR036603RNA polymerase, RBP11-like subunitSUPERFAMILYSSF55257RBP11-like subunits of RNA polymerasecoord: 8..261
NoneNo IPR availablePANTHERPTHR11800DNA-DIRECTED RNA POLYMERASEcoord: 1..261
NoneNo IPR availablePANTHERPTHR11800:SF2DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3coord: 1..261