E3 ubiquitin-protein ligase MARCH6

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARR-ENLRLLHLTEQ-AGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            DT    D CRVCR   T  + L++PC+CTGSIK++HQ+CL+QWLKHS++E+CELCK++FAF PIYS DMP+RLP+  +  GL +SI  A+  W HY+LVA AWL VVPLTACRI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P WLE                  NA  ++ N      N   NV     A P         N + Q +Q    E  N  E        A  N+    G Q   N+N L+W R  EELTWE+++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHF++VG    + +  +  +G+ITTI+GY+++A  L+I H L   ++     +   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF++TL  R   FQ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I+  +P FLPY      D+P+      L L  V+       GHT  WLK ++R W +T   LLDL S++LGD    E         N        I    +      +   L   GP G ++PY++P    F LR F LI  + I+ +  S I L +PV+ GR +++   G     +L +  CGL       +A   +      G   I +   ++    L++ K +++ ++    +PL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +    +IEQ  A    N+ L ++  + A P+++ + L++  P+V +  + P+  +     + V+RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    2 DTAE-EDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAAPPF------------NAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEEDDAGVEDAADANN----GAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVK---FHRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVVGE-GLHAAHQAILQQGGPVG-FQPYRRPLN--FPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQ---KVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLK---TVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYER 893          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARR-ENLRLLHLTEQ-AGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            DT    D CRVCR   T  + L++PC+CTGSIK++HQ+CL+QWLKHS++E+CELCK++FAF P                                                 RI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P WLE                  NA  ++ N      N   NV     A P         N + Q +Q    E  N  E        A  N+    G Q   N+N L+W R  EELTWE+++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHF++VG    + +  +  +G+ITTI+GY+++A  L+I H L   ++     +   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF++TL  R   FQ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I+  +P FLPY      D+P+      L L  V+       GHT  WLK ++R W +T   LLDL S++LGD    E         N        I    +      +   L   GP G ++PY++P    F LR F LI  + I+ +  S I L +PV+ GR +++   G     +L +  CGL       +A   +      G   I +   ++    L++ K +++ ++    +PL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +    +IEQ  A    N+ L ++  + A P+++ + L++  P+V +  + P+  +     + V+RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    2 DTAE-EDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTP------------------------------------------------SRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAAPPF------------NAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEEDDAGVEDAADANN----GAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVK---FHRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVVGE-GLHAAHQAILQQGGPVG-FQPYRRPLN--FPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQ---KVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLK---TVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYER 845          

Query:  472 RICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARR-ENLRLLHLTEQ-AGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            RI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P WLE                  NA  ++ N      N   NV     A P         N + Q +Q    E  N  E        A  N+    G Q   N+N L+W R  EELTWE+++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHF++VG    + +  +  +G+ITTI+GY+++A  L+I H L   ++     +   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF++TL  R   FQ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I+  +P FLPY      D+P+      L L  V+       GHT  WLK ++R W +T   LLDL S++LGD    E         N        I    +      +   L   GP G ++PY++P    F LR F LI  + I+ +  S I L +PV+ GR +++   G     +L +  CGL       +A   +      G   I +   ++    L++ K +++ ++    +PL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +    +IEQ  A    N+ L ++  + A P+++ + L++  P+V +  + P+  +     + V+RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    8 RIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAAPPF------------NAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEEDDAGVEDAADANN----GAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVK---FHRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVVGE-GLHAAHQAILQQGGPVG-FQPYRRPLN--FPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQ---KVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLK---TVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYER 788          

Query: 1210 AFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARR-ENLRLLHLTEQ-AGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            A  L+I H L   ++     +   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF++TL  R   FQ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I+  +P FLPY      D+P+      L L  V+       GHT  WLK ++R W +T   LLDL S++LGD    E         N        I    +      +   L   GP G ++PY++P    F LR F LI  + I+ +  S I L +PV+ GR +++   G     +L +  CGL       +A   +      G   I +   ++    L++ K +++ ++    +PL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +    +IEQ  A    N+ L ++  + A P+++ + L++  P+V +  + P+  +     + V+RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:   42 AITLIICHGLATLVK---FHRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVVGE-GLHAAHQAILQQGGPVG-FQPYRRPLN--FPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQ---KVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLK---TVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYER 591          

Query:  154 DFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAP 324
            D CRVCR   T  + L++PC+CTGSIK++HQ+CL+QWLKHS++E+CELCK++FAF P
Sbjct:    7 DICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTP 63          

Query:  970 DWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPM-DYSLEILFLQVVLPMLFD-GHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRN-VLNVGGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHL-TEQAGPLVAFVTLAITGPFVFSKTIAPIFFLDDHY---VYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            +W R G+ELTW++L+GLDGSL FLEHVFW++SLNTLF   FA+ P+ IG++ +    L   IS+     I+  ++GY+ IA    ++H+++   ++K + +     G+ F+IIKV L   LEIG  P++CG W+D+C+L +FN TL QR   F  AP   IF+HW VG++Y+FY ASF++LL+E+LRPG+ WF++N NDP+FNPIQ+MI     R  +R  ++ +LF   I ++ +IP  +I   IP  LPY    + ++P+ + SLE+L LQVV+P + +  +   ++K  +RFWC  +   LDL  ++L D      +   N    +      R   N         +  L        Y PY +P    FG+R   L+  + ++T   S ++ IVP  IGR  +L V G     ++ ++  GL     + K   ++  KF+ G   +  F+  +++   +  +L ++ I   + +PL +G    L   +P+R+   ++ ++  +++W  G++ +KI+ +I + GP WW +  LD++ Q     EN   LH+      P + +++  I  P V  K  A I   D  +   + R  YP   F+   ++ I +Q  +   L E IKN+RYLVG QLVNYER
Sbjct:  393 EWDRFGDELTWQRLLGLDGSLIFLEHVFWVISLNTLFTATFAYFPFRIGNWFLSVIGLHGKISY--FPSIVAMLLGYIQIAIITYVIHQIMLQFKMKMMYR---FLGIMFLIIKVFLLVFLEIGFFPVMCGCWMDVCTLPLFNITLSQRIATFATAPFMSIFLHWMVGMVYVFYSASFVILLREILRPGVLWFMRNLNDPDFNPIQEMIDLPFTRHFRRLVVSTTLFFSTILLIFYIPLNIISSLIPSLLPYNVSMSAETPLSEISLELLILQVVMPAILEHANGRGFIKYGVRFWCKVVGAALDLDQYLLSDNNNNNQNNNNNNNDPL------RAGNNQAGGGLAAEHQALLLLREPRAYEPYNRPS--LFGVRVSILLVLMSLTTTLSSVVVFIVPASIGRFIILMVSGQTNVHEMYTVSLGLYVCWTIGKFG-AVVTKFVRGGPHL--FKRAVVHYSYLGMRLFLVAIPIIIVLPLLMGTYFQLVFFTPMRLGYQQTALMFPYQDWAMGVVQIKIFGVIAVMGPDWWLKTELDLLVQRGI--ENFAALHVFVRIVVPCILYLSTFIAFPVVVIKFYAFISGADPEFTMLLLRFSYPAFLFITSAVVFIRWQVVKFRELAEKIKNDRYLVGTQLVNYER 1016          

Query:  118 DNIEESDTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPE 657
            D I + + ++L   CRVCR       +L+YPCLCTGSIKYVHQ+CL++WLK+SK+E CELC +K++F PIY  DMP  LP+  +++G+  S    V +W+ Y++V   WL +VPLTA RI   +F  S   ++  P  +   +H F D L G +++ + + TF+  +W+REQI+I GGP+
Sbjct:   41 DPIIDDNDDHL--MCRVCRGNEG---SLYYPCLCTGSIKYVHQECLVEWLKYSKKEVCELCNHKYSFQPIYRQDMPKALPILEILRGVLISGAIMVRTWIIYTIVMTTWLGIVPLTAARIYNCIFYLSFHDIVNAPFQLFKAEHFFNDILKGSLLLLVFVCTFISLVWLREQIII-GGPQ 214          

Query:  109 SDIDNIEESDTENLNDFCRVCRC--GATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREF-----CELCKYKF 312
            S + ++  SD  N    CR+C C      N  L  PC C+GS++YVH  CLM WL  S R+      CELC YK+
Sbjct:  178 SSVYSLARSDMSN-EPLCRICHCCWPPDSNDPLISPCRCSGSLQYVHVSCLMHWLDISSRKLHRPAICELCLYKY 251          

Query:  106 MSDIDNIEESDTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAP 324
            +  I + +E  T+ +   CR+C    T + +L  PC C+G++ YVH  CL QW++ +    C +C+  F   P
Sbjct:    9 LETIRSPKEVSTKTV--ICRICFDNDTSSDSLIKPCSCSGTVAYVHNGCLEQWVRTTSNIQCTICQDMFELIP 79          

Query:  121 NIEESDTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFA-----FAPIYSADMP 345
            +  ES T      CR+C+        +  PC C G++  VH++CL +W+  S ++ CE+CK ++      F PI     P
Sbjct:   39 SFSESTTSGSRRICRICQMHEG---DMVRPCDCAGTMGDVHEECLTKWVNMSNKKTCEICKSEYTNSGAQFKPIKQWSKP 115          

Query:  160 CRVCRCGAT--------LNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPL 462
            CR+C CG T            L  PC C+G++   H+ CL  WL  +    CE+CK+ F           +R  +  + QG +  ++     ++ ++ V    LL++P 
Sbjct:   13 CRICMCGETSIPYLGQQAGEPLISPCKCSGTMGLFHRSCLEHWLTLTSTTNCEICKFAFKIK------QKSRNFIDYIRQGGYKKLQSNRNPFIDFAFV----LLILPF 111          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLF-TGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLE 666
            D  +  D CRVCRC A  +R LFYPC+CTGSIKY+HQDCLM W+++S +E+CELC Y F+F PIY+ DMP  LP+  ++ GL S++      WLHY+LV +AW  VVPL+A R  R LF   S   +LTLP D+ S +++  D   G  VV  TL +F+  +W+REQI+  GGP+WLE
Sbjct:    2 DDLSQGDICRVCRCEAQPDRPLFYPCICTGSIKYIHQDCLMLWMRYSHKEYCELCSYSFSFQPIYAPDMPRVLPIKDVLVGLMSAVLEGARCWLHYTLVGLAWFGVVPLSAYRTYRYLFRASSFDMILTLPFDIFSVENLASDAFRGCFVVTCTLLSFIGLVWLREQILHGGGPDWLE 179          

Query: 2359 LVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            L +LGI  FV +PL +GLLI L V+ P+RVPL K+ I   WE+W  G+++ KI + + + GP W  +  LD    +  R  +L+ + + + A P+V  + LA+  P+V +  + PIF  D    H V R +YP  F +   I I+ FQ  Q+ +LY  IK ++YLVGQ+LVNYE 
Sbjct:  771 LTLLGI--FVLVPLLIGLLIELAVVIPLRVPLRKTPIHFLWEDWALGVLYCKIAIALTMMGPDWHLKRALDRAYMDGLRDFDLKFV-MRDLAVPVVTTIGLALAIPYVMAHMMFPIFLADAYAQHVVARLVYPVSFIVVGSICILLFQIDQLKKLYLSIKVDKYLVGQRLVNYEH 942          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLF-TGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLE 666
            D  +  D CRVCRC A  +R LFYPC+CTGSIKY+HQDCLM W+++S +E+CELC Y F+F PIY+ DMP  LP+  ++ GL S++      WLHY+LV +AW  VVPL+A R  R LF   S   +LTLP D+ S +++  D   G  VV  TL +F+  +W+REQI+  GGP+WLE
Sbjct:    2 DDLSQGDICRVCRCEAQPDRPLFYPCICTGSIKYIHQDCLMLWMRYSHKEYCELCSYSFSFQPIYAPDMPRVLPIKDVLVGLMSAVLEGARCWLHYTLVGLAWFGVVPLSAYRTYRYLFRASSFDMILTLPFDIFSVENLASDAFRGCFVVTCTLLSFIGLVWLREQILHGGGPDWLE 179          

Query: 2359 LVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            L +LGI  FV +PL +GLLI L V+ P+RVPL K+ I   WE+W  G+++ KI + + + GP W  +  LD    +  R  +L+ + + + A P+V  + LA+  P+V +  + PIF  D    H V R +YP  F +   I I+ FQ  Q+ +LY  IK ++YLVGQ+LVNYE 
Sbjct:  771 LTLLGI--FVLVPLLIGLLIELAVVIPLRVPLRKTPIHFLWEDWALGVLYCKIAIALTMMGPDWHLKRALDRAYMDGLRDFDLKFV-MRDLAVPVVTTIGLALAIPYVMAHMMFPIFLADAYAQHVVARLVYPVSFIVVGSICILLFQIDQLKKLYLSIKVDKYLVGQRLVNYEH 942          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLF-TGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLE 666
            D  +  D CRVCRC A  +R LFYPC+CTGSIKY+HQDCLM W+++S +E+CELC Y F+F PIY+ DMP  LP+  ++ GL S++      WLHY+LV +AW  VVPL+A R  R LF   S   +LTLP D+ S +++  D   G  VV  TL +F+  +W+REQI+  GGP+WLE
Sbjct:    2 DDLSQGDICRVCRCEAQPDRPLFYPCICTGSIKYIHQDCLMLWMRYSHKEYCELCSYSFSFQPIYAPDMPRVLPIKDVLVGLMSAVLEGARCWLHYTLVGLAWFGVVPLSAYRTYRYLFRASSFDMILTLPFDIFSVENLASDAFRGCFVVTCTLLSFIGLVWLREQILHGGGPDWLE 179          

Query: 2359 LVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            L +LGI  FV +PL +GLLI L V+ P+RVPL K+ I   WE+W  G+++ KI + + + GP W  +  LD    +  R  +L+ + + + A P+V  + LA+  P+V +  + PIF  D    H V R +YP  F +   I I+ FQ  Q+ +LY  IK ++YLVGQ+LVNYE 
Sbjct:  771 LTLLGI--FVLVPLLIGLLIELAVVIPLRVPLRKTPIHFLWEDWALGVLYCKIAIALTMMGPDWHLKRALDRAYMDGLRDFDLKFV-MRDLAVPVVTTIGLALAIPYVMAHMMFPIFLADAYAQHVVARLVYPVSFIVVGSICILLFQIDQLKKLYLSIKVDKYLVGQRLVNYEH 942          

Query:  139 TENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKF 312
            ++N  D CR+C C +     L  PC C+GS+KYVHQ CL QWL  S+   CELCK+ F
Sbjct:   36 SQNSGDICRICHCESDPQNPLLTPCYCSGSLKYVHQACLQQWLTASETNSCELCKFPF 93          

Query:  139 TENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKF 312
            ++N  D CR+C C +     L  PC C+GS+KYVHQ CL QWL  S+   CELCK+ F
Sbjct:   36 SQNSGDICRICHCESDPQNPLLTPCYCSGSLKYVHQACLQQWLTASETNSCELCKFPF 93          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            DT    D CRVCR   T ++ L++PC+CTGSIK++HQ+CL+QWLKHS++E+CELCK++FAF PIYS DMP+RLPV  +  GL +SI  A+  W HY+LVA AWL VVPLTACRI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P WLE       N     +   G       N    A    P    A    PD   D A     E+M  +  +E+    E V   N           G Q   N+N L+W R  EELTWE+++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHF++VG    + +  +  +G+ITTI+GYV++A  L++ H L   +R    ++   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF+++L  R   F+ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I+   P FLPY      D+P+      L L  V+       GHT  WLK ++R W +T   LLDL S++LGD    E +       N Q+     I    +      +   L   GP G ++PY +P +  F LR   LI  + ++ +  S + L +PV+ GR +++   G     +L +  CGL       +A   L      G   I     ++    L++ K +++ ++    IPL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +  ++ +     R  +L  + + + A P++A + L++  P+V +  I P+  +     + V RRIYP L  +  L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    2 DTAEEADICRVCRSEGTQDKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPVQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPLWLEQNQQQPANAAGPPNEAPGQGNGGAENQPMPAPAEPPAENAAAAEAPDLPADPA-----EEMELDNEDEDDGGAEDVADANN----------GAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSVVGLGFEEYVRASHFEGLITTIVGYVLLAITLIVCHGLAALVR---FQRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDASLKDRELSFESAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVVVFGSIVLLMLWLPIRIIKHIFPSFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEDNENNANQQANNNNQQARNNAIPVVGE-GLHAAHQAILQQGGPVG-FQPYHRPMK--FPLRIVLLILFMCVTLLLASLVCLTLPVFTGRWLMSFWTGSAKIHELYTAACGLYVCWLSIRAITVLLAWMPQGRRVI---LLKIQEWTLMIMKTLIVAVLLAGVIPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHFI-IRKLAAPVIAVLLLSLCIPYVIAVGIVPLLGVTMEMQNLVQRRIYPFLLMVVFLMGILSFQIRQFKRLYEHIKNDKYLVGQRLVNYER 895          

Query: 2032 GPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDG----DIQRF------RTRLINGVLIL---WKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIF 2709
            GP G ++PY +P +  F LR   LI  + ++ +  S + L +PV+ GR +++   G     +L +  CGL       +A   L      G       IQ +       + L NGV  +    K +++ ++    IPL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +  ++ +     R  +L  + + + A P++A + L++  P+V +  I P+ 
Sbjct:    3 GPVG-FQPYHRPMK--FPLRIVLLILFMCVTLLLASLVCLTLPVFTGRWLMSFWTGSAKIHELYTAACGLYVCWLSIRAITVLLAWMPQGRRVILLKIQEWTLMLQDSSCLKNGVTCIAQIMKTLIVAVLLAGVIPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHFI-IRKLAAPVIAVLLLSLCIPYVIAVGIVPLL 238          

Query:  133 SDTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKF 312
            S T +  D CR+C C       L  PC CTGS+++VHQ CL QW+K S    CELCKY F
Sbjct:   44 SVTPSNQDICRICHCEGDDESPLITPCHCTGSLRFVHQACLQQWIKSSDTRCCELCKYDF 103          

Query:  133 SDTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGL--FSSIKRAVLSWLHYSLVAIA---WLLVV 456
            S T +  D CR+C C       L  PC CTGS+++VHQ CL QW+K S    CELCKY F         M T+L      + L   +S +R ++  + + ++AI    W L V
Sbjct:   44 SVTPSNQDICRICHCEGDDESPLITPCHCTGSLRFVHQACLQQWIKSSDTRCCELCKYDFI--------METKLKPLRKWEKLQMTASERRKIMCSVTFHVIAITCVVWSLYV 148          

Query:  127 EESDTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKF 312
            + S T +  D CR+C C       L  PC CTGS+++VHQ CL QW+K S    CELCKY F
Sbjct:   63 QTSVTHSSQDICRICHCEGDEECPLITPCHCTGSLRFVHQGCLHQWIKSSDTRCCELCKYDF 124          

Query:  151 NDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
             D CRVCR   T  + L++PC+CTGSIK++HQ+CL+ WLKHS++E+CELCK++FAF PIYS DMP+RLP+  +  GL +SI  A+  W HY+LVA AWL VVPLTACRI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P+WLE       N+  Q + +  N   +N+  LD   N  P   N +     DIQ++   + EE  +        +A +A N              G Q   N+N L+W R  EELTWE+++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHF++VG      +  +  +G+ITTI+GYV++A  L++ H L   ++    ++   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF++TL  R   FQ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I+  +P FLPY      D+P+      L L  V+       GHT  WLK ++R W +T   LLDL S++LGD    E +       N Q      +    +      +   L   GP G ++PY++P +  F LR   LI  + I+ +  S I L +PV+ GR +++   G     +L +  CGL  + +LT  + ++   ++     +   + +     L++ K +V+ ++    +PL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +  ++ +     R  +L  + +   A P+++ + L++  P++ +  I P+  +     + V RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    6 EDICRVCRSEGTSEKPLYHPCVCTGSIKFIHQECLVLWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPIQDICAGLITSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPQWLEQNQPPPLNVLGQQNEVPANIAADNMA-LDQPAN--PPAGNPVVGENPDIQEEQADDEEEDNDDEEDAVIEDAADANN--------------GAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSVVGLGFEDYVRASHFEGLITTIVGYVLLAVTLILCHALAAVVK---FQRSRRLLGICYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKHMLPTFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENNANQQAANNNQHARNNAVPVVGE-GLHAAHQAILQQGGPVG-FQPYRRPVK--FPLRILLLIIFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGL-YVCWLTIRAVTVLVAWMPQGRRVILLKVK--EWSLMIIKTLVVALLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHFI-IRRLAAPVISVLLLSLCIPYIIAAAIVPVIGVTAEMQNLVQRRIYPFLLMVVVLMGILSFQIRQFKRLYEHIKNDKYLVGQRLVNYER 892          

Query:  151 NDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIV--------SLNTLFILVF-AFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
             D CRVCR   T  + L++PC+CTGSIK++HQ+CL+ WLKHS++E+CELCK++FAF PIYS DMP+RLP+  +  GL +SI  A+  W HY+LVA AWL VVPLTACRI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P+WLE       N+  Q + +  N   +N+  LD   N  P   N +     DIQ++   + EE  +        +A +A N              G Q   N+N L+W R  EELTWE+++GLDGSL FL   F +             L++  F AFCPYHIGHF++VG      +  +  +G+ITTI+GYV++A  L++ H L   ++    ++   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF++TL  R   FQ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I+  +P FLPY      D+P+      L L  V+       GHT  WLK ++R W +T   LLDL S++LGD    E +       N Q      +    +      +   L   GP G ++PY++P +  F LR   LI  + I+ +  S I L +PV+ GR +++   G     +L +  CGL  + +LT  + ++   ++     +   + +     L++ K +V+ ++    +PL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +  ++ +     R  +L  + +   A P+++ + L++  P++ +  I P+  +     + V RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    6 EDICRVCRSEGTSEKPLYHPCVCTGSIKFIHQECLVLWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPIQDICAGLITSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPQWLEQNQPPPLNVLGQQNEVPANIAADNMA-LDQPAN--PPAGNPVVGENPDIQEEQADDEEEDNDDEEDAVIEDAADANN--------------GAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLVGTFNLKINIILLYDYCQVLYLFTFAAFCPYHIGHFSVVGLGFEDYVRASHFEGLITTIVGYVLLAVTLILCHALAAVVK---FQRSRRLLGICYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKHMLPTFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENNANQQAANNNQHARNNAVPVVGE-GLHAAHQAILQQGGPVG-FQPYRRPVK--FPLRILLLIIFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGL-YVCWLTIRAVTVLVAWMPQGRRVILLKVK--EWSLMIIKTLVVALLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHFI-IRRLAAPVISVLLLSLCIPYIIAAAIVPVIGVTAEMQNLVQRRIYPFLLMVVVLMGILSFQIRQFKRLYEHIKNDKYLVGQRLVNYER 901          

Query:  151 NDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVF-AFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
             D CRVCR   T  + L++PC+CTGSIK++HQ+CL+ WLKHS++E+CELCK++FAF PIYS DMP+RLP+  +  GL +SI  A+  W HY+LVA AWL VVPLTACRI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P+WLE       N+  Q + +  N   +N+ L   A    P   N +     DIQ++   + EE  +        +A +A N              G Q   N+N L+W R  EELTWE++      +   ++         L++  F AFCPYHIGHF++VG      +  +  +G+ITTI+GYV++A  L++ H L   ++    ++   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF++TL  R   FQ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I+  +P FLPY      D+P+      L L  V+       GHT  WLK ++R W +T   LLDL S++LGD    E +       N Q      +    +      +   L   GP G ++PY++P +  F LR   LI  + I+ +  S I L +PV+ GR +++   G     +L +  CGL  + +LT  + ++   ++     +   + +     L++ K +V+ ++    +PL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +  ++ +     R  +L  + +   A P+++ + L++  P++ +  I P+  +     + V RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    6 EDICRVCRSEGTSEKPLYHPCVCTGSIKFIHQECLVLWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPIQDICAGLITSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPQWLEQNQPPPLNVLGQQNEVRSNIAADNMALDQPAN---PPAGNPVVGENPDIQEEQADDEEEDNDDEEDAVIEDAADANN--------------GAQDDMNWNALEWDRAAEELTWERVNTGANRILLYDYC------QVLYLFTFAAFCPYHIGHFSVVGLGFEDYVRASHFEGLITTIVGYVLLAVTLILCHALAAVVK---FQRSRRLLGICYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKHMLPTFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENNANQQAANNNQHARNNAVPVVGE-GLHAAHQAILQQGGPVG-FQPYRRPVK--FPLRILLLIIFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGL-YVCWLTIRAVTVLVAWMPQGRRVILLKVK--EWSLMIIKTLVVALLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHFI-IRRLAAPVISVLLLSLCIPYIIAAAIVPVIGVTAEMQNLVQRRIYPFLLMVVVLMGILSFQIRQFKRLYEHIKNDKYLVGQRLVNYER 887          

Query:  472 RICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFW----IVSL----NTLFILVFA-FCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            RI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P+WLE       N+  Q + +  N   +N+ L D   N  P   N +     DIQ++   + EE  +        +A +A N              G Q   N+N L+W R  EELTWE+++GLDGSL FL   F     I+ L      L++  FA FCPYHIGHF++VG      +  +  +G+ITTI+GYV++A  L++ H L   ++    ++   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF++TL  R   FQ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I+  +P FLPY      D+P+      L L  V+       GHT  WLK ++R W +T   LLDL S++LGD    E +       N Q      +    +      +   L   GP G ++PY++P +  F LR   LI  + I+ +  S I L +PV+ GR +++   G     +L +  CGL  + +LT  + ++   ++     +   + +     L++ K +V+ ++    +PL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +  ++ +     R  +L  + +   A P+++ + L++  P++ +  I P+  +     + V RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:   49 RIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPQWLEQNQPPPLNVLGQQNEVPANIAADNMAL-DQPAN--PPAGNPVVGENPDIQEEQADDEEEDNDDEEDAVIEDAADANN--------------GAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLVGTFNLKINIILLYDYCQVLYLFTFAAFCPYHIGHFSVVGLGFEDYVRASHFEGLITTIVGYVLLAVTLILCHALAAVVK---FQRSRRLLGICYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKHMLPTFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENNANQQAANNNQHARNNAVPVVGE-GLHAAHQAILQQGGPVG-FQPYRRPVK--FPLRILLLIIFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGL-YVCWLTIRAVTVLVAWMPQGRRVILLKVK--EWSLMIIKTLVVALLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHFI-IRRLAAPVISVLLLSLCIPYIIAAAIVPVIGVTAEMQNLVQRRIYPFLLMVVVLMGILSFQIRQFKRLYEHIKNDKYLVGQRLVNYER 837          

Query:  151 NDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDC 252
             D CRVCR   T  + L++PC+CTGSIK++HQ+C
Sbjct:    6 EDICRVCRSEGTSEKPLYHPCVCTGSIKFIHQEC 39          

Query:  154 DFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAF 318
            D CR+C C       L  PCLCTG++++VHQ CL QW+K S    CELCKY F  
Sbjct:  263 DVCRICHCEGDEENPLITPCLCTGTLRFVHQTCLHQWIKSSDTRCCELCKYDFVM 317          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXX--XXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARR-ENLRLLHLTEQ-AGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            DT    D CRVCR   T  + L++PC+CTGSIK++HQ+CL+QWLKHS++E+CELCK++FAF PIYS DMP+RLP+  +  GL +SI  A+  W HY+LVA AWL VVPLTACRI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P WLE           +     + GN   N     D   N  P   NA+     D QD      EE   +       +A +A N              G Q   N+N L+W R  EELTWE+++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHF++VG    + +  +  +G+ITTI+GY+++A  L+I H L   ++     +   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF++TL  R   FQ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I+  +P FLPY      D+P+      L L  V+       GHT  WLK ++R W +T   LLDL S++LGD    E +   N + N  +  +              +   L   GP G ++PY++P    F LR F LI  + I+ +  S I L +PV+ GR +++   G     +L +  CGL       +A   L      G   I +   ++    L++ K +++ ++    +PL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +    +IEQ  A    N+ L ++  + A P+++ + L++  P+V +    P+  +     + V+RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    2 DTAE-EDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAAPPFNAAGHHQNEAPVGGNGAENPAA--DQPAN--PAGENAVLGENPDAQDGQAEEEEEDNEEEDDAGVEDAADANN--------------GAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHALATLVK---FHRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKSLLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQE--ENENSANQQVNNNQPARNNNAVPAGEGLHAAHQAILQQGGPVG-FQPYRRPLN--FPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVLVAWMPQGRRVIFQ---KVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLK---TVIEQVYANGIRNIDLHYIIRKLAAPVISVLLLSLCVPYVIASGAVPLLGVTAEMQNLVHRRIYPFLLMVVVLMGILSFQVRQFKRLYEHIKNDKYLVGQRLVNYER 892          

Query:  133 SDTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGL--FSSIKRAVLSWLHYSLVAIA---WLLVVPLTACRICRSLFTGSVSSLLTLPL 528
            S T +  D CR+C C       L  PC CTGS+ +VHQ CL QW+K S    CELCKY+F         M T+L      + L   +S +R ++  + + ++AI    W L V +   R    +  G V+ +L  P 
Sbjct:   28 SVTPSNQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFI--------METKLKPLRKWEKLQMTASERRKIMCSVTFHVIAITCVVWSLYVLID--RTAEEIKQGQVTGILEWPF 154          

Query:  133 SDTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKF 312
            S T +  D CR+C C       L  PC CTGS+ +VHQ CL QW+K S    CELCKY+F
Sbjct:   67 SVTPSNQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEF 126          

Query:  133 SDTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGL--FSSIKRAVLSWLHYSLVAIA---WLLVVPLTACRICRSLFTGSVSSLLTLPL 528
            S T +  D CR+C C       L  PC CTGS+ +VHQ CL QW+K S    CELCKY+F         M T+L      + L   +S +R ++  + + ++AI    W L V +   R    +  G V+ +L  P 
Sbjct:   67 SVTPSNQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFI--------METKLKPLRKWEKLQMTASERRKIMCSVTFHVIAITCVVWSLYVLID--RTAEEIKQGQVTGILEWPF 193          

Query:  133 SDTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGL--FSSIKRAVLSWLHYSLVAIA---WLLVVPLTACRICRSLFTGSVSSLLTLPL 528
            S T +  D CR+C C       L  PC CTGS+ +VHQ CL QW+K S    CELCKY+F         M T+L      + L   +S +R ++  + + ++AI    W L V +   R    +  G V+ +L  P 
Sbjct:   67 SVTPSNQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFI--------METKLKPLRKWEKLQMTASERRKIMCSVTFHVIAITCVVWSLYVLID--RTAEEIKQGQVTGILEWPF 193          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXX--XXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARR-ENLRLLHLTEQ-AGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            DT    D CRVCR   T  + L++PC+CTGSIK++HQ+CL+QWLKHS++E+CELCK++FAF PIYS DMP+RLP+  +  GL +SI  A+  W HY+LVA AWL VVPLTACRI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P WLE           +     + GN   N     D   N  P   NA+     D QD      EE   +       +A +A N              G Q   N+N L+W R  EELTWE+++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHF++VG    + +  +  +G+ITTI+GY+++A  L+I H L   ++     +   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF++TL  R   FQ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I+  +P FLPY      D+P+      L L  V+       GHT  WLK ++R W +T   LLDL S++LGD    E +   N + N  +  +              +   L   GP G ++PY++P    F LR F LI  + I+ +  S I L +PV+ GR +++   G     +L +  CGL       +A   L      G   I +   ++    L++ K +++ ++    +PL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +    +IEQ  A    N+ L ++  + A P+++ + L++  P+V +    P+  +     + V+RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    2 DTAE-EDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAAPPFNAAGHHQNEAPVGGNGAENPAA--DQPAN--PAGENAVLGENPDAQDGQAEEEEEDNEEEDDAGVEDAADANN--------------GAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHALATLVK---FHRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKSLLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQE--ENENSANQQVNNNQPARNNNAVPAGEGLHAAHQAILQQGGPVG-FQPYRRPLN--FPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVLVAWMPQGRRVIFQ---KVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLK---TVIEQVYANGIRNIDLHYIIRKLAAPVISVLLLSLCVPYVIASGAVPLLGVTAEMQNLVHRRIYPFLLMVVVLMGILSFQVRQFKRLYEHIKNDKYLVGQRLVNYER 892          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARR-ENLRLLHLTEQ-AGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            DT    D CRVCR   T  + L++PC+CTGSIK++HQ+CL+QWLKHS++E+CELCK++FAF PIYS DMP+RLP+  +  GL +SI  A+  W HY+LVA AWL VVPLTACRI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P WLE                  NA  ++ N      N   NV     A P         N + Q +Q    E  N  E        A  N+    G Q   N+N L+W R  EELTWE+++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHF++VG    + +  +  +G+ITTI+GY+++A  L+I H L   ++     +   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF++TL  R   FQ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I+  +P FLPY      D+P+      L L  V+       GHT  WLK ++R W +T   LLDL S++LGD    E         N        I    +      +   L   GP G ++PY++P    F LR F LI  + I+ +  S I L +PV+ GR +++   G     +L +  CGL       +A   +      G   I +   ++    L++ K +++ ++    +PL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +    +IEQ  A    N+ L ++  + A P+++ + L++  P+V +  + P+  +     + V+RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    2 DTAE-EDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAAPPF------------NAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEEDDAGVEDAADANN----GAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVK---FHRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVVGE-GLHAAHQAILQQGGPVG-FQPYRRPLN--FPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQ---KVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLK---TVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYER 893          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLFDGHTVFW--LKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARR-ENLRLLHLTEQ-AGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            DT    D CRVCR   T  + L++PC+CTGSIK++HQ+CL+QWLKHS++E+CELCK++FAF PIYS DMP+RLP+  +  GL +SI  A+  W HY+LVA AWL VVPLTACRI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P WLE                  NA  ++ N      N   NV     A P         N + Q +Q    E  N  E        A  N+    G Q   N+N L+W R  EELTWE+++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHF++VG    + +  +  +G+ITTI+GY+++A  L+I H L   ++     +   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF++TL  R   FQ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I+  +P FLPY      D+P+      L L  V+              + ++R W +T   LLDL S++LGD    E         N        I    +      +   L   GP G ++PY++P    F LR F LI  + I+ +  S I L +PV+ GR +++   G     +L +  CGL  + +LT  + ++   ++   G    F+ ++    L++ K +++ ++    +PL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +    +IEQ  A    N+ L ++  + A P+++ + L++  P+V +  + P+  +     + V+RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    2 DTAE-EDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAAPPF------------NAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEEDDAGVEDAADANN----GAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVK---FHRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQRTHEAVAEGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVVGE-GLHAAHQAILQQGGPVG-FQPYRRPLN--FPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGL-YVCWLTIRAVTVMVAWMP-QGRRVVFQ-KVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLK---TVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYER 893          

Query: 1303 IIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLFDGHTV-FWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTR------------------INENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-----GGFDVFC-DLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVL-ILWK--------LVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFG------PRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIF---FLDDHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNY 2868
            +IKVA   ++E+G+ PL+CG W+D+C++ MF  T+  R      +P     +HW VG+MY+   + F+ LL+ +LRPG+ +FL++  DPN+NP +D+I   V +  +R  ++ +++G +I ++V++P KL     P   P    S  D   +   ++L  Q+ +P + +   +   +K+++R W   +   L L  F+L   P  E D I    GN +   Q R                   ++ N S  R  N N   T     +        R  F +R   L+    ++ + F++ +++VPV +GR + +          + C DL + + G  + AF T  S + Y         I+  +++  + +L  +WK         V+L I  F+ IP+ +GLL  L V+ P+RVP+D+S +   +++W  G++ LKIW  +++           W  +   + E   +R + L +L   E   P+V  +  A+  P+V ++ + P+     + +  VYR  +     + L              L+  I+++RYL+G++L N+
Sbjct:  522 MIKVAFLLVIELGVFPLMCGWWLDVCTVRMFGKTMSHRVQFLSISPLASSLVHWVVGIMYMLQISIFVSLLRGVLRPGVLYFLRDPADPNYNPFRDLIDDPVHKHARRVLLSVAVYGSLIVMLVFLPVKLAIRMAPSIFPLDI-SVSDPFTEIPADMLLFQICIPFIIEHFRLRTTIKSLLRCWFTGVGWALGLTDFLL---PRPE-DNIGQDNGNGEPGRQNRAQVLQVGGPDRAMAALPVADDPNRSRLRAGNVN---TGEEYEDDDEQSDSDRYNFVVRIILLLLVAWVTLLLFNSALIVVPVSLGRALFSAIPILPITHGIKCNDLYAFVIG--TYAFWTTISGARYA--------IEHVKSKRTSVLLNQIWKWCGIVFKSSVLLAIWVFI-IPVLIGLLFELLVIVPMRVPVDESPVFLLYQDWALGLIFLKIWTRLVMLDHMLPIVDDSWRAKFERVREDGFSRLQGLWVLR--EIVFPIVMKLLTALCVPYVLARGVFPMLGYPLVVNSAVYRFAWIGCLSVSLFCFCAKRCHVWFRNLHNSIRDDRYLIGRRLHNF 1065          

Query:  160 CRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGN-----------------------FNLDWGRGGEELTWEKLIGLDGSLFFL-EHVFWIVSLNTLFILVFAFCPYHIGH 1119
            CR+CR     +  L YPC C+GSIK+VHQDCL+QWL HS    CE+CK+ F+F+P+Y+ + P+RLP    V G+       +  +L  S V   WLL +P     I R  F  +      L L  +ST  I  DCL+G +     L   + F++                                    +   +L D  R+     L  LG G ++  DD + N      +  G  N N      + NG+ AG+    +G     N                         LD   G E++ +++L+G+ G +F L E+ F +++ N +F+ V  F P+ +G 
Sbjct:   68 CRICRNPGDADNPLRYPCACSGSIKFVHQDCLLQWLNHSNARQCEVCKHPFSFSPVYADNAPSRLPFQEFVVGIAMKACHVLQFFLRLSFVLSVWLLTIPFITFWIWRLAFVRTFGEAQRLFLSHISTTVILTDCLHGFL-----LSASIVFIF------------------------------------LGATSLRDYFRH-----LRELG-GQEERDDDVDRNGARAARRPAGQANRN---LAGEGNGEDAGDQGAAVGQIARRNPENVLARLDIQAARLEAQVEQMFDGLDDADGAEDVPFDELVGMQGPVFHLVENAFTVLASNMIFLGVVIFVPFTLGR 361          

Query:  151 NDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPL 462
            ++ CRVCRC    +  LF+PC CTGSI+YVHQ+CL++WL HSK+  CELCK KF F  +YS  MP  +P  IL + L S++K+ V+ +    L    W +++PL
Sbjct:    5 DEICRVCRCEGAPDSPLFHPCKCTGSIRYVHQECLVEWLGHSKKTHCELCKAKFEFTKVYSESMPRTIPFTILCRKLASTLKQRVIFFTRVLLTFFCWTVLLPL 108          

Query: 1303 IIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRH-NLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFL-PYKFQSTK---DSPMD-YSLEIL-FLQVVLPMLFDGHTVFWLKTIIRFWCITISNLLDLRSFMLGD-VPFLEGDIIMNYEGNIQRVI-QTRINENNDSSFRQTNNNHLATQG-----PSGNYRPYKK-----------------PKR---------CYFGLRFFA-----LIFCVLISTIAFSTIILIVPVYIGRNVL-----NVGGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGD---GDIQRFRTRLINGVLIL-WKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDK-SIILSFWENWMFGMMHLKI 2517
            I K  +   +E+ + P+ CG+ + +C +  F     +   N+    PA  IF+ W +G+ ++F FA F+ ++++++RPG+ +FL++ NDP F+PI++++ + +   +K+   +  L+    FI+  + + +  +   G + P +F +     ++P+D  +LEIL FL + L    +    FW +T++  +C      L L S+++G      EG     Y   ++R+I +    EN D   +Q         G     PS +  P ++                  K+          Y    F+      L+FC + ST+  + +++ VP+ +GR +      NV   D +   +    G  SI+F   A ++   KFL  D     + +   +++   L++  K ++L  +    +PL LG +  L V  P R   ++ ++ L  ++NW+ G+  L++
Sbjct:  661 IAKFGIIFSIELVVFPIFCGILLSMCLIGTFKKLAAENLLNVMTVYPAQSIFLAWFIGITFMFEFAVFISMVRKIVRPGVLYFLRDPNDPQFHPIREILEKPMLFQLKKIGFSAILY--FAFIIGCVGSVIHLLKSTGIIFPIEFTTKPAVFEAPIDLLALEILIFLSIKLFKPLELTRSFW-RTLVSTFC----RCLRLSSYVMGQRYSDEEGYYPKQYFSFLRRIISKPSDTENQDDGDKQKAKKDFVQDGFFLWCPSKDVVPVRQGAMLIPVTENGYEIFGEKKKVEENADYTITYAPSNFYKRLIALLLFCWICSTLV-TVLLVFVPLSLGRAIYAWCFPNVVKHDFYAYAI----GFYSISFPMYAIHASV-KFLKLDYLRSLMNKLNLKIVMRSLVMALKYLLLAFLGIFILPLLLGAIWELYVAIPFRTIFNRGTLALDAFQNWVIGLFMLRM 1107          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDD--IQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFNLDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSP-MDYSLEILFLQVVLPMLFD-GHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSS-------------------------FRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV---GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIF---FLDDHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            D   L D CRVCR     ++ LF+PC+CTGSIKY+HQDCL+QWLK+S++E+CELC ++F+F PIYS DMP RLP+  +V GL SS+  A+  WLHY++VA AWL +VPLTACRI R LFTGSVSSLLTLPLDMLST+++  D LYG  +V  TL  F+  +W+REQ++   GP+WLE                 G A      ++      +P+      A  DD   QDD NWN                                            ++W R  EELTWE+L+GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIG F I+GF L   ++ ++ +G++TT+ GYV++   L+ LH L   ++++  ++   + GL ++++KVAL +++EIG+ PL+CG W+D+CSLSM ++TL  R + FQ AP TF+F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNPIQ+MI   + + ++RF ++  +FG  + +MVW+P +LI+  +PGFLPY    + +SP  + SLE++ LQVVLP L + GH   WLK ++R WC+ ++ LLDLRS++LGD P  + +     EG  Q    +++    +                               +   L   GPS  ++ Y++P+  +F LR  AL+ C+  S  A S  +L +PV +GR V+ V   GG     +  +  CGL S     +    L      G   I    ++L + +LI  K +V   +    IPL +GLL +L V+ P+RVPL+ + +   W +W  G++H KI   + L GP WW +  +D + Q+  R+ NLRL+ +      +V  + LA+  P++ + ++ P F       + V RRIYP+L  L   +  + FQ RQ  RLYEHIKN++YLVG++LVNYE 
Sbjct:    2 DDSQLQDICRVCRSEGAPDKPLFHPCICTGSIKYIHQDCLVQWLKYSRKEYCELCNHRFSFMPIYSPDMPKRLPIRDIVSGLLSSLGTAIRYWLHYTVVAFAWLGIVPLTACRIYRCLFTGSVSSLLTLPLDMLSTENLLSDSLYGCCIVTCTLCAFISLVWLREQVIHGEGPDWLEQDPQHA----------EGLAEAEPGEVVGPPLGPVPHHAEEPPAQADDHVAQDDINWN-------------------------------------------PIEWDRAAEELTWERLLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGQFAIMGFRLKSYVAVSQFEGLLTTLCGYVLLGVVLVFLHGLAALVKLRRTQR---LLGLCYVVVKVALLSVVEIGLFPLVCGWWLDVCSLSMLDATLSDRESSFQLAPGTFMFLHWLVGMVYVFYFASFVLLLREVLRPGLLWFLRNLNDPDFNPIQEMIHLPILQHVRRFLVSLVIFGTTVLLMVWVPVRLIQCLLPGFLPYHVLISSESPSQEISLELILLQVVLPTLLEQGHMKQWLKALVRAWCVGVACLLDLRSYLLGDAPDTQTEQDGAAEGGQQAGDGSQLMGPLNEVDDEVDDEEEEDEEDDEEEAGAAPVVLGAAHQALLQGPGPSA-FQAYQRPR--WFPLRLAALLCCIAFSLTALSFAMLTIPVSMGRLVMMVLMPGG--RVHEFYTAACGLYSCWLALRCLTLLCSWLPRGWNTI---LSKLHSWMLISVKSLVAMSLLLGLIPLLMGLLFDLVVIIPLRVPLNATPLFYLWHDWALGVLHTKIICAVTLMGPNWWLKRVIDEMYQDGVRQLNLRLVVMDLVVP-VVVVLGLALAVPYLLATSLVPAFGSSMETQNLVLRRIYPSLLALCAFMAFMVFQVRQFCRLYEHIKNDKYLVGRRLVNYEH 884          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQII--------------------GNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLATQ------GPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLIN-----GVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            DT    D CRVCR   T ++ L++PC+CTGSIK++HQ+CL+QWLKHS++E+CELCK++FAF PIYS DMP+RLPV  ++ GL +SI  A+  W HY+LVA AWL VVPLTACR+ + LFTGSVSSLLTLP+DMLS +++  DCL G  VV  TL  F+  +W+REQI+  G P+WLE                                  L    N  G  P+++  + N   E Q      N +A   EAVN    Q      +                      G Q   N+N LDW R  EELTWE+++GLDGSL FLEHVFW++SLNTLFILVFAFCPYHIGHF++VG      I  +  DG+ITTI+GYV++A  L++ H L   +R    ++   + G+ +I++KV+L  ++EIGI PL+CG W+DICSL MF+++L  R   F  AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I++ +P FLPY      D+P+      L L  V+       GHT  WLK ++R W +T   LLDL S++LGD    + D         Q+    +   N +++       H A Q      GP G ++PY++P R  F  R   LI  + ++ +A S I L +PV+ GR +++   G     +L +  CGL       +A   L      G       RT LI       V+IL  LVV  +VT V IPL LGLL    +++P+RVPLD++ +   W++W  G++H KI   + L GP+WW +  ++ +     R  +L  + + + A P+++ + L++  P+V +  I P+  +     + V RRIYP L  + +LI I++FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    2 DTAEEADICRVCRSEGTPDKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPVQDILAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRMYKCLFTGSVSSLLTLPIDMLSMENLLADCLQGCFVVTCTLCAFIGLVWLREQIVHGGAPQWLEQN--------------------------------LEQPPNEAGQ-PNEVPGEENGPAENQ--PVVPNGHAEEEEAVNDPEAQLDAEEDEDGDDEDEDEEDDAAEDGEEANNGAQDDMNWNALDWDRAAEELTWERMLGLDGSLVFLEHVFWVISLNTLFILVFAFCPYHIGHFSVVGLGFEDYIEASHFDGLITTIVGYVLLAVTLIVCHGLAALVR---FQRSRRLLGVCYIVVKVSLLVVVEIGIFPLICGWWLDICSLEMFDASLKDRELSFDSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVVVFGSIVLLMLWLPIRIIKLVVPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEESDDD-------GQQQANNNQQVRNEEAAPAVGEGLHAAHQAILQQGGPVG-FQPYRRPVR--FPFRIVLLIAFMCVTLLATSLICLTLPVFAGRWLMSFWTGSAKVHELYTAACGLYVCWLSVRAVTVLLAWMPQG-------RTVLILKVQEWSVMILKSLVVAFLVTGV-IPLLLGLLFEQVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAVTLMGPQWWLKAVIEQVYANGIRNMDLHFI-IQKLAVPVISVLLLSLCVPYVIAAGIVPVMGVTVEMQNLVQRRIYPFLLMVVMLIGILFFQIRQFKRLYEHIKNDKYLVGQRLVNYER 895          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXX-----XXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIF--------FLDDHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            DT    D CRVCR   TL++ L++PC+CTGSIK++HQ+CL+QWLKHS++E+CELCK++FAF PIYS DMP+RLPV  +  GL +S+  A+  W HY+LVA AWL VVPLTACRI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P+WLE      Q+        Q  G    A  N    +           N   A   DIQ D   ++E +       + A A +  +  NG            Q   N+N L+W R  EELTWE+++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHFT+VG    + +  +  +G+ITTI+GY+++A  L++ H L   +R    ++  H+ G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF+++L  R   F  AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P + I++ +P FLPY      D+P+      L L  V+       GHT  WLK ++R W +T   LLDL S++LGD    E +     +       +   N          +   L   GP G  +PY +P +  F  R   LI  + ++ +  S   L +PV+ GR +++   G     +L +  CGL       +    L      G   I     ++    L++ K VV+ ++    IPL LGLL  + +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +  ++ +     R  +L  + + + A P++  + +++  P+V S  I PI             + V RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    2 DTAEEGDICRVCRSEGTLDKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPVQDIFAGLLTSVGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPQWLEQNQQQPQHAPAPQPNEQAPGPGQGAAENQPAPVAAEPP----ADNGPAAEVPDIQMDPAEDMELE-------DEAGAEDVADANNGA-----------QDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFTVVGLGFEENVRASHFEGLITTIVGYILLAMLLILCHGLAALVR---FQRSRHLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDASLKDRELSFDSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVVVFGSIVLLMLWLPIRTIKLILPAFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQ---EENDDDADQQANNNQQRRNNNNAIPEGLHAAHQAILQQGGPVG-VQPYHRPMK--FTFRIVLLIVFMCVTLLVASLACLTLPVFTGRYLMSFWTGSAKIHELYTAACGLYVCWLSIRVITVLLSWMPQGRRAI---LLKVQEWTLMILKTVVIAVLLAGAIPLLLGLLFEMVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHFI-IRKLAAPVICVLLVSLCVPYVISAGIVPIVAQYSPGVTMEMQNLVQRRIYPFLLMVVMLLGILSFQIRQFKRLYEHIKNDKYLVGQRLVNYER 896          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXG---IAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIFFLDDHY---VYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            DT    D CRVCR   T  + L++PC+CTGSIK++HQ+CL+QWLKHS++E+CELCK++FAF PIYS DMP+RLPV  +  GL +S+  A+  W HY+LVA AWL VVPLTACRI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P+WL+ +         Q+     + G  +  +    +   N       A+G    DIQ D    +E +     G E+             A  N+    G Q   N+N L+W R  EELTWE+++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHFT+VG      +  +  +G++TTI+GY+++A  L++ H L   +R    ++   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF+++L  R   F+ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I++ +P FLPY      D+P+      L L  V+       GHT  WLK ++R W ++   LLDL S++LGD    EG+   + + + Q   Q   N+N         +  +  QG    ++PY++P +  F  R   LI  + ++ +  S + L +PV+ GR +++   G     +L +  CGL       +A   L      G G +     ++    L++ K VV+ ++    IPL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +  ++ +     R  +L  + + + A P++  + +++ GP+V S  I PI  +       V RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    2 DTAEEADICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPVQDIFAGLVTSVGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPQWLDQQQQPQHAPAAQHQEQDPVPGQELGEDQVAAEPQAND-----AAVGDDVPDIQVDPAEEMELEDEDEAGAEDV------------ADANN----GAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFTVVGLGFEDNVRSSHFEGLVTTILGYILLAMTLILCHGLAALVR---FQRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDASLKDRELSFESAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVVVFGSIVLLMLWLPVRMIKLLLPAFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVSAGYLLDLHSYLLGDQ---EGE---DNDADQQANNQPGRNDNAIPQGLHAAHQAVLQQGGPVGFQPYRRPMK--FSFRIVLLILFMCVTLMVASLLCLTLPVFTGRYLMSFWTGSAKIHELYTAACGLYVCWLSIRAVTVLPGWMPRGRGVV---LLKVQEWALMILKTVVVAVLLAGAIPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHFI-IRKLAAPVLCVLLVSLCGPYVISAGIVPIVGVTMEMQILVQRRIYPFLLMVVMLLGILSFQIRQFKRLYEHIKNDKYLVGQRLVNYER 888          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLA--TQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            DT    D CRVCR   T ++ L++PC+CTGSIK++HQ+CL+QWLKHS++E+CELCK++FAF PIYS DMP+RLPV  +  GL +SI  A+  W HY+LVA AWL VVPLTACRI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P WLE       N     +   G       N    A    P    A    PD   D A     E+M  +  +E     E V   N           G Q   N+N L+W R  EELTWE+++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHF++VG    + +  +  +G+ITTI+GYV +A  L++ H L   +R    ++   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF+++L  R   F+ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I+   P FLPY      D+P+      L L  V+       GHT  WLK ++R W +T  +LLDL S++LGD    + D   N       + Q   N          +  H A   QG    ++PY +P +  F LR   LI  + ++ +  S + L +PV+ GR +++   G     +L +  CGL       +A   L      G   I     ++    L++ K +++ ++    IPL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +  ++ +     R  +L  + + + A P++A + L++  P+V S  I P+  +     + V RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    2 DTAEEADICRVCRSEGTQDKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPVQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPLWLEQNQQQPANAAGPPNEAPGQGNGGAENQPMPAPAEPPGENAAAAEAPDLPADPA-----EEMELDNDDEEDGGAEDVADANN----------GAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSVVGLGFEEYVRASHFEGLITTIVGYVPLAITLIVCHGLAALVR---FQRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDASLKDRELSFESAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVVVFGSIVLLMLWLPIRIIKHIFPSFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGHLLDLHSYLLGD----QEDNENNANQQANNINQQARNNAIPVVGEGLHAAHQAILQQGGPVGFQPYHRPMK--FPLRIVLLILFMCLTLLLASLVCLTLPVFTGRWLMSFWTGSAKIHELYTAACGLYVCWLSIRAITVLLAWMPQGRRVI---LLKVQEWTLMIMKTLIVAVLLAGVIPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHFI-IRKLAAPVIAVLLLSLCIPYVISVGIVPLIGVTMEMQNLVQRRIYPFLLMVVVLMGILSFQIRQFKRLYEHIKNDKYLVGQRLVNYER 895          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENN----DSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            DT    D CRVCR   TL++ L++PC+CTGSIK++HQ+CL+QWLKHS++E+CELCK++FAF PIYS DMP+RLPV  +  GL +SI  A+  W HY+LVA AWL VVPLTACRI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P WLE       N   Q +  AG       N    A    P         P+   D A    E+    N   E A   +A +  NG            Q   N+N L+W R  EELTWE+++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHF++VG      +  +  +G+ITTI+GYV++A  L++ H L   +R    ++   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF+++L  R   F+ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I+  +P FLPY      D+P+      L L  V+       GHT  WLK ++R W +T   LLDL S++LGD      +   N         Q R N N            +   L   GP G ++PY +P +  F LR   LI  + ++ +  S + L +PV+ GR +++   G     +L +  CGL  + +L+  + ++   ++     +   + +     L++ K +++ ++    IPL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +  ++ +     R  +L  + + + A P++A + L++  P+V +  I PI  +     + V RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    2 DTGEEADICRVCRSEGTLDKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPVQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPLWLEQNQQQPANAAAQANEAAGAGNGGADNQPVPAPAEPPAENAVPAEVPEVPPDPA----EDLELDNDDEEEAGGEDAADANNGA-----------QDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSVVGLGFEDYVRASHFEGLITTIVGYVLLAIALIVCHGLAALVR---FQRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDASLKDRELSFESAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVVVFGSIVLLMLWLPIRIIKHILPAFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQ----EENENNANQAANNNQQPRNNANAIPVVGEGLHAAHQAILQQGGPVG-FQPYHRPMK--FPLRIVLLILFMCVTLLLASLLCLTLPVFAGRWLMSFWTGSAKIHELYTAACGL-YVCWLSIRAITVLLAWMPQGRRVILLKVQ--EWTLMIMKTLIVAVLLAGVIPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHFI-IRKLAAPVIAVLLLSLCVPYVIAVGIVPIVGVTMEMQNLVQRRIYPFLLMVVVLMGILSFQIRQFKRLYEHIKNDKYLVGQRLVNYER 896          

Query:  958 NFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENN----DSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIFFLD---DHYVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNER 2838
            N+N L+W R  EELTWE+++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHF++VG      +  +  +G+ITTI+GYV++A  L++ H L   +R    ++   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF+++L  R   F+ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I+  +P FLPY      D+P+      L L  V+       GHT  WLK ++R W +T   LLDL S++LGD      +   N         Q R N N            +   L   GP G ++PY +P +  F LR   LI  + ++ +  S + L +PV+ GR +++   G     +L +  CGL  + +L+  + ++   ++     +   + +     L++ K +++ ++    IPL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +  ++ +     R  +L  + + + A P++A + L++  P+V +  I PI  +     + V RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++
Sbjct:  161 NWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSVVGLGFEDYVRASHFEGLITTIVGYVLLAIALIVCHGLAALVR---FQRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDASLKDRELSFESAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVVVFGSIVLLMLWLPIRIIKHILPAFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQ----EENENNANQAANNNQQPRNNANAIPVVGEGLHAAHQAILQQGGPVG-FQPYHRPMK--FPLRIVLLILFMCVTLLLASLLCLTLPVFAGRWLMSFWTGSAKIHELYTAACGL-YVCWLSIRAITVLLAWMPQGRRVILLKVQ--EWTLMIMKTLIVAVLLAGVIPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHFI-IRKLAAPVIAVLLLSLCVPYVIAVGIVPIVGVTMEMQNLVQRRIYPFLLMVVVLMGILSFQIRQFKRLYEHIKNDK 784          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLE 666
            DT    D CRVCR   TL++ L++PC+CTGSIK++HQ+CL+QWLKHS++E+CELCK++FAF P                                                 RI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P WLE
Sbjct:    2 DTGEEADICRVCRSEGTLDKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTP------------------------------------------------SRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPLWLE 130          

Query:  154 DFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKF 312
            + CR+C C    +  L  PC CTGS+++VHQ CL QW+K S    CELCKY F
Sbjct:  285 EVCRICHCEGDEDCPLITPCRCTGSLRFVHQACLHQWIKSSDTRCCELCKYDF 337          

Query:  133 SDTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKF 312
            S T +  D CR+C C       L  PC CTGS+++VHQ CL QW+K S    CELCK++F
Sbjct:  178 SVTPSNQDICRICHCEGDDESPLITPCHCTGSLRFVHQACLQQWIKSSDTRCCELCKFEF 237          

Query:  154 DFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKF 312
            + CR+C C    +  L  PC CTGS+++VHQ CL QW+K S    CELCKY F
Sbjct:  300 EVCRICHCEGDEDCPLITPCRCTGSLRFVHQACLHQWIKSSDTRCCELCKYDF 352          

Query:  151 NDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFNLDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGF 1137
            ++ CRVCR   T+++ LF+PC+CTGSIK++HQDCL+QWLKHS++E+CELCK++F F PIYS DMP RLPV  +V GL +S+  A+  W HY+LVA AWL VVPLTACRI + LFTG VSSLLTLP+DMLST++I +DCL G +VV  TL  F+  +W+REQIM  G P WLE                         +L   A   +P V++ L     D +      + + +  +  ++          E  + AG++      + +    L+W R  EELTWE+++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHF+++G 
Sbjct:    5 HNICRVCRSEGTVDKPLFHPCVCTGSIKFIHQDCLLQWLKHSRKEYCELCKHRFTFTPIYSPDMPPRLPVGDVVAGLLASVGTALRFWFHYTLVAFAWLGVVPLTACRIYKCLFTGCVSSLLTLPMDMLSTENILVDCLQGCLVVTCTLCAFISLVWLREQIMHGGAPPWLEQN-----------------------HLAARANGTIPVVIDEL-----DPEPPGEARVAQALPADAEDDEDEENVDEGDEEEEQAGDNANNDAQEDMNWNALEWDRAAEELTWERILGLDGSLIFLEHVFWVVSLNTLFILVFAFCPYHIGHFSVIGL 305          

Query: 1387 SMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRV---IQTRINENNDSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV--GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGD-IQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIFFLDDH---YVYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
             MF++T+  R   FQ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   +FR  +RF ++  +FG I+ +M+W+P ++I+  +P FLPY      D+P+      L L  V+       GHT  WLK ++R W  T + LLDL S++LGD      +   N     +     I   I E   ++     +  +  QG    ++PY +P   +F LR F LI C+ ++ ++ S   L+VPV  GR ++++  GG  +  +L +  CGL +     + +  L      G    +QR + R     L++ K ++   +    +PL +GLL  L V+ P+RVPL ++ +    ++W  G++H KI   I L GP+W  +  ++ +     R  ++R+L L E  GP+ A + LA+  P+  S  + P+  L         RR+YP L    L++ ++  Q RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    1 EMFDATMKDREASFQSAPGTTMFLHWLVGMVYVFYFASFVLLLREVLRPGVLWFLRNINDPDFNPVQEMIHLPLFRHARRFLLSTVVFGSIVVLMLWLPIRIIKGTLPSFLPYNVTLYSDAPVSELSLELLLLQVVLPALLEQGHTRHWLKGLLRAWTRTAAYLLDLHSYLLGDQDEENENNAENAREEEEEERNGIAVPIVEGLHAA-----HQAMLQQGGPTEFQPYTRP--LHFTLRIFLLIGCICLTLLSSSLTCLVVPVLAGRYIMSMWAGGLKLH-ELYTAACGLYACWLAARGATVLASWAPQGRRVLLQRLKER----TLMVLKTLLAAFLLAGVVPLLVGLLFELVVVVPLRVPLHQTPLFFPLQDWALGVLHTKIVAAITLMGPQWRLKAAIEQVYANGLRNLDMRVL-LLELTGPVTAALLLALCVPYAVSFGLVPLLGLSAETQTLAERRVYPCLLGGCLVLGVLGAQLRQFRRLYEHIKNDKYLVGQRLVNYER 494          

Query:  151 NDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLE 666
             D CRVCR   T+++ LF+PC+CTGSIK++HQDCL+QWLKHS++E+CELCK++F F PIYS DMP RLPV  +V GL +S+  A+  W HY+LVA AWL VVPLTACRI + LFTG VSSLLTLP+DMLST++I +DCL G +VV  TL  F+  +W+REQIM  G P WLE
Sbjct:    1 TDICRVCRSEGTVDKPLFHPCVCTGSIKFIHQDCLLQWLKHSRKEYCELCKHRFTFTPIYSPDMPPRLPVGDVVAGLLASVGTALRFWFHYTLVAFAWLGVVPLTACRIYKCLFTGCVSSLLTLPMDMLSTENILVDCLQGCLVVTCTLCAFISLVWLREQIMHGGAPPWLE 172          

Query:  154 DFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTA 468
            D CRVCR   T  + L++PC+CTGSIKY+HQDCL+QWLKHSK+E+CELCK++FAF PIYS DMP+RLP+  ++ GLF S+   V  WLHY+LVA AWL VVPLTA
Sbjct:    3 DICRVCRSEGTAEKPLYHPCVCTGSIKYIHQDCLLQWLKHSKKEYCELCKHRFAFTPIYSPDMPSRLPLRDILAGLFRSVCTGVRFWLHYTLVAFAWLGVVPLTA 107          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKF 312
             T+ L  F R+C C       L  PC CTGS+++VHQ CL QW+K S    CELC Y F
Sbjct:   13 HTQLLCSF-RICHCEGDEEGPLTAPCQCTGSLQFVHQACLQQWIKSSGASCCELCNYSF 70          

Query:  127 EESDTENLND------FCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREF--------CELCKYKFAFAPIYSADMPTRLPVAILV-QGLFSSIKRAVLSWLHYSLVAIAWLLVVPL 462
            EE+DT   ND       CR+CR  AT +  LF+PC C GSIKY+H+ CL++W+     +         C++C Y   F  IY+ +MP ++P ++L+ + + +  ++A L+ L   L A+ +++ VPL
Sbjct:   22 EETDTATFNDDAPSGATCRICRGEATEDNPLFHPCKCRGSIKYMHESCLLEWVASKNIDISKPGADVKCDICHYPIQFKTIYAENMPEKIPFSLLLSKSILTFFEKARLA-LTIGLAAVLYIIGVPL 147          

Query: 1309 KVALFTILEIGIVPLLCGVWIDI---CSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXX-XXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDS-PMDYSLEIL----FLQVVLPMLFDG---HTVFWLKTIIRFWCITI----SNLLDLRSFMLG-DVPFLEGDII 1929
            KV     +E+   P+L GV +D    C +   NS +    ++    P   +F++WT+G +Y++ +     ++ K ++RPG+ +F+++  DPN   + D +   +   + R C++  ++ I I +      ++       F P+  +S   S P  Y    +    F  ++L + F      +  ++K ++  +  TI    S  L L SF+LG D P   G I+
Sbjct:  625 KVFTLFFIELAGFPILAGVMLDFSLFCPILASNSRMLWVPSICAIWPPFSLFVYWTIGTLYMYWFAKYIGMIRKNIIRPGVLFFIRSPEDPNIKILHDSLIHPMSIQLSRLCLSMFIYAIFIVLGFGFHTRI-------FFPFMLKSNLLSVPEAYKPTSIISWKFNTILLTLYFTKRILESSSYVKPLLERYWKTIFKLCSRKLRLSSFILGKDTPTERGHIV 841          

Query:  154 DFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAI-EAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHL-----ATQGPSG---NYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNV--LNVGGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIFFLDDHYV---YRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYE 2871
            D CRVCR   T ++ L++PC+CTGSIKY+HQ+CL+QWLKHSK+E+CELC ++F F PIY+ DMP  LPV   + GL  SI RAV  W HY+LVAIAWL VVP+TA RI R LF GSVSSLLTLPLDMLST+++F+DC+ G  VV  TL  F+  +W+REQI++NGGP+WLE     +  L     G      V     + G  +++            DI+D  +        +N   E+A+   EA   EN    G    +       N+N ++W R  EELTWE+++GLDGSL FLEHVFW+VSLNT FILVFAFCP+HIG F ++ F++ + +  ++ +G+ITT++GY+I+A  L+I H +  +   K   +   I GL ++++KV+L  ++EIG+ PL+CG W+DICSL++F +TL +R      AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+F+P+Q+MI   V R  +RF ++  +FG  + +M+++P  LI+  +P FLPY  Q + ++P+      L L  V+       GHT  WLK +I+ W +T + +LDLRS+++GDVP L+G ++ N   N+       +N + + +  Q     L     A   P G    ++PY +PK   F +    +  C+ +S  +F  +IL VPV +GR V  L +G   V  +L +  CGL  I  + +    +      G   I +   +L + +L+  K V++ +V    +PL LGLL  L V+ P+RVPLD++ +   W++W  G++H+KI   + + GP WW +  L+ +  +  R  N  L+ L   A P+V  + LA+T P+V +  I PIF      V    RRIYP L  + +LI    FQ RQ   LYE IKN++YLVGQ+LVNYE
Sbjct:    6 DICRVCRAEGTPDKPLYFPCICTGSIKYIHQECLLQWLKHSKKEYCELCNHRFTFKPIYAPDMPPHLPVRDFISGLSRSILRAVRYWFHYTLVAIAWLGVVPITAYRIYRCLFAGSVSSLLTLPLDMLSTENVFMDCVRGCFVVACTLCAFISLVWLREQIVLNGGPDWLEPNMDPLPQLPANLFGGPQGVNVGAGGGVFGGADVM-----------GDIEDPGD-------QENMEEEDADPPDEAELPENAANNGEADDV-------NWNPVEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTSFILVFAFCPFHIGQFAVILFSVEEAVQSSRFEGVITTVLGYIILAASLVICHTVSSFFSFKRARR---IFGLCYVVVKVSLLMVVEIGLFPLVCGWWLDICSLALFGATLKERVQSIGSAPGTAMFLHWLVGMVYVFYFASFVLLLREVLRPGVLWFLRNLNDPDFHPVQEMIRLPVHRHARRFLLSLVVFGTTVLLMMYLPVSLIKAFVPSFLPYNVQLSSEAPVSELSLELLLLQVVLPALLEQGHTRQWLKNLIKGWAVTAAYILDLRSYLIGDVP-LDG-LVNNAPVNLN------VNPDQNGAELQGPQAQLIPQPQAAHNPDGAVFGFQPYIRPKMFVFKIVLLVIFMCMSLSFASF--VILTVPVGVGRAVMCLWMGSLAVH-ELYTAACGLYLIWLVCRTFAVIMSWVPLGVIGIAK---KLGHWMLLGLKCVLIAVVLIGVVPLLLGLLFELIVVVPLRVPLDQTPLYFPWQDWALGVLHMKIICAVTMMGPNWWLKAILEQVYNDGIRNINTVLI-LRRLAVPVVVCLLLAVTVPYVIANGIIPIFISSADTVVFCQRRIYPFLLAVFMLIGCFMFQGRQFKMLYERIKNDKYLVGQRLVNYE 885          

Query:  808 DIQDDANWNIEEQMNQNFGNENANAI-EAVNQENGQAAGNHPQIIGNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKV 1314
            DI+D  +       ++N   E+A+   EA   EN  AA N     G     N+N ++W R  EELTWE+++GLDGSL FLEHVFW+VSLNT FILVFAFCP+HIG F ++ F++ + +  ++ +G+ITT++GY+I+A  L+I H +  ++  K   +   I GL ++++K+
Sbjct:   35 DIEDPGD-------HENMEEEDADPPDEAELPEN--AANN-----GEADDVNWNPVEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTSFILVFAFCPFHIGQFAVILFSVEEAVQSSRFEGVITTVLGYIILAASLVICHAVSSFLSFK---RARRIFGLCYVVVKM 188          

Query:  154 DFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADM-PTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIA 441
            + CR+C C A  ++ L  PC C+GS++YVHQ CL +W+K S  + CELC Y+F    I  A M P R   A+    +  S +R ++  + + ++AI 
Sbjct:    8 EICRICHCEAEPDQPLISPCHCSGSLQYVHQTCLQRWIKSSDTKKCELCNYEF----IMEAKMKPFRKWQAL---DMTRSERRKIMCSVSFHIIAIT 97          

Query:   85 LPNKFK*MSDIDNIEESDTENL-----NDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAF----APIYSADMPTRLPVAIL 369
            LP + + + +++N  +     +      D CR+C CG   +  L  PCLC G++++VH  CLM WL+   +  CELC Y  A      P+     P   P  I+
Sbjct:  166 LPQEIENICELENTTQEARAEIPDELDGDACRICHCGGE-SEVLISPCLCMGTVRFVHHSCLMDWLQRCVKTKCELCLYPVAVRRKTKPLKKWRPPDEKPTPII 268          

Query:  106 MSDIDNIEESDTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAF----APIYSADMPTRLPVAIL 369
            MSD  + E ++T+N+   CR+C         L  PC C+GS K+VH  CL+ W K + +  CELC+ K A      P      P   P+ ++
Sbjct:   99 MSDRGSWEVAETQNI---CRICHSAG--EEPLVTPCHCSGSAKFVHATCLLTWFKKAVKNTCELCRCKVAIKKKGKPFAEWRKPEDKPIPLI 185          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQE-NGQAAGNHPQII------------------------------GNQGVGNFN---LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENN----DSSFRQTNNNHLATQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARR-ENLRLLHLTEQ-AGPLVAFVTLAITGPFVFSKTIAPIFFLDDHY---VYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            DT    D CRVCR   T ++ L++PC+CTGSIK++HQ+CL+QWLKHS++E+CELCK++FAF PIYS DMP+RLPV  +  GL +SI  A+  W HY+LVA AWL VVPLTACRI + LFTGSVSSLLTLPLDMLST ++  DCL G  VV  TL  F+  +W+REQI+  G P+WLE                                 L+PN  N    GP    +DA  N  +              +   +  +  AAGNH +                                 N G  + N   L+W R  EELTWE+++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHF++VG      I  +  DG+ITTI+GY+++A  L+  H L   ++    ++   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF+++L  R   F  AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P ++I++  P FLPY      D+P+      L L  V+       GHT  WLK ++  W  T    LDL S++LGD            E N    I  R N N            +   L   GP G ++PY +P    F L+   L+  + ++ +  S I L +PV++GR ++++  G  +  +L +   GL       +A+  L      G   I     ++    L++ K VV+ ++    IPL LGLL  L V+ P+RVPLD++ +   W++W  G++H KI   I L GP+WW +    +IEQ  A    N+ L ++  + A P++  + L++  P+  SK I P+  +       V RRIYP L  + +L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    2 DTAEEADICRVCRSEGTQDKPLYHPCVCTGSIKFIHQECLLQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPVQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTQNLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPQWLEQI----------------------------PPPLVPNQPN----GPAAANEDAGANAADDGQAAAAEPPPADPDPDGRPGDPHAAGNHREEAELDDDDGDDNGEDEDDEEEEEDGREDGADANNGGQEDLNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSVVGLGFEDYIKASHFDGLITTILGYILLAGALIACHALASLVK---FQRSRRLLGVCYIVVKVSLLVVMEIGLFPLICGWWLDICSLEMFDASLKDREQSFDSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFVLSVVVFGSIVLLMLWLPIRIIKLLFPTFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKRLVHAWTYTAGYALDLHSYLLGD---------HEEEENQPNNIPDRQNNNRFPGLGEGLHAAHQAILQQGGPVG-FQPYHRPPN--FPLKIVLLVVFMCVTLLLASLICLTLPVFVGRWLMSLWMGSALVHELYTAASGLYVCWLSIRAATVLLSWMPQGRTVIM---LKVHEWTLMIIKTVVIAVMLAGVIPLLLGLLFELVVVVPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLK---TVIEQVYANGIRNIDLHYIVRRLAAPVICVLLLSLCVPYTISKGITPLLGVQPEMQTLVERRIYPFLLMVVVLLAILSFQIRQFKRLYEHIKNDKYLVGQRLVNYER 907          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXG-----IAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFNLDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLA--TQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIFFLDDHY---VYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            DT    D CRVCR   T ++ L++PC+CTGSIK++HQ+CL+QWLKHS++E+CELCK++FAF PIYS DMP+RLP+  +  GL +S+  A+  W HY+LVA AWL VVPLTACRI + LFTGSV  +LT       T+++  DCL G  VV  TL  F+  +W+REQI+  G P+WLE       N   Q  G      A           + A    P+     G  PD  ++ A     +  N    + N NA+E                          L W R         ++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHF++VG    + +  +  +G+ITTI+GY+++A  L++ H L   +R    ++   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF++TL  R   F+ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P KLI++ +P FLPY      D+P+      L L  V+       GHT  WLK ++R W ++   LLDL S++LG+    E +  +N   N         N    +     +  H A   QG    ++PY +P R  F  R   LI  + I+ +  S + L +PV+ GR +++   G     +L +  CGL       + +  L      G   I R   ++    +++ K VV+ ++    IPL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +  ++ +     R  +L  + + + A P+++ + L++  P+V +  + P   +       + RRIYP L  +  L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:    2 DTAEEADICRVCRSEGTPDKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPIQDICAGLLTSVGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSV--MLT------QTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPQWLEQHQPPPPNQARQPQGAAEDPPAAQPAPAEPPAQNEAEPEPPDAPPDQGEDPDLEEEGAAAEDADPNNGAQDDMNWNALEWDRAAE-------------------ELTWER---------MLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSVVGLGFEEYVQASHFEGLITTIVGYILLAITLILCHGLAALVR---FQRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDREMSFKSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVVVFGSIVLLMLWLPIKLIKVMLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVSAGYLLDLHSYLLGEQEDNETNQPVNNNNNPPHGQPNNNNNPPPAVGEGLHAAHQAILQQGGPVGFQPYHRPVR--FPFRIVLLIAFMCITLLVASLVCLTLPVFTGRWLMSFWMGNSKIHELYTAACGLYVCWLSIRGATVLLAWMPQGRTVIMR---KVQEWTMMILKTVVVALLVAGVIPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHFI-IRKLAAPVISVLLLSLCVPYVIAAGVVPAVGVAPEMEILMQRRIYPFLLMVVSLVGILSFQIRQFKRLYEHIKNDKYLVGQRLVNYER 882          

Query:  940 GNQGVGNFN-LDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDMITQSVFRLIKRFCINCSLFGIIIFIMVWIPNKLIRICIPGFLPYKFQSTKDSPMDYSLEILFLQVVLPMLF--DGHTVFWLKTIIRFWCITISNLLDLRSFMLGDVPFLEGDIIMNYEGNIQRVIQTRINENNDSSFRQTNNNHLA--TQGPSGNYRPYKKPKRCYFGLRFFALIFCVLISTIAFSTIILIVPVYIGRNVLNV-GGFDVFCDLVSLLCGLCSIAFLTKASYSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIFFLDDHY---VYRRIYPTXXXXXXXXXXXXXQFRQMYRLYEHIKNERYLVGQQLVNYER 2874
            G Q   N+N L+W R  EELTWE+++GLDGSL FLEHVFW+VSLNTLFILVFAFCPYHIGHF++VG    + +  +  +G+ITTI+GY+++A  L++ H L   +R    ++   + G+ +I++KV+L  ++EIG+ PL+CG W+DICSL MF++TL  R   F+ AP T +F+HW VG++Y+FYFASF+LLL+E+LRPG+ WFL+N NDP+FNP+Q+MI   ++R ++RF ++  +FG I+ +M+W+P KLI++ +P FLPY      D+P+      L L  V+       GHT  WLK ++R W ++   LLDL S++LG+    E +  +N   N         N    +     +  H A   QG    ++PY +P R  F  R   LI  + I+ +  S + L +PV+ GR +++   G     +L +  CGL       + +  L      G   I R   ++    +++ K VV+ ++    IPL LGLL  L +++P+RVPLD++ +   W++W  G++H KI   I L GP+WW +  ++ +     R  +L  + + + A P+++ + L++  P+V +  + P   +       + RRIYP L  +  L+ I+ FQ RQ  RLYEHIKN++YLVGQ+LVNYER
Sbjct:  180 GAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSVVGLGFEEYVQASHFEGLITTIVGYILLAITLILCHGLAALVR---FQRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDREMSFKSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVVVFGSIVLLMLWLPIKLIKVMLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVSAGYLLDLHSYLLGEQEDNETNQPVNNNNNPPHGQPNNNNNPPPAVGEGLHAAHQAILQQGGPVGFQPYHRPVR--FPFRIVLLIAFMCITLLVASLVCLTLPVFTGRWLMSFWMGNSKIHELYTAACGLYVCWLSIRGATVLLAWMPQGRTVIMR---KVQEWTMMILKTVVVALLVAGVIPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHFI-IRKLAAPVISVLLLSLCVPYVIAAGVVPAVGVAPEMEILMQRRIYPFLLMVVSLVGILSFQIRQFKRLYEHIKNDKYLVGQRLVNYER 824          

Query:  340 MPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLE 666
            MP+RLP+  +  GL +S+  A+  W HY+LVA AWL VVPLTACRI + LFTGSVSSLLTLPLDMLST+++  DCL G  VV  TL  F+  +W+REQI+  G P+WLE
Sbjct:    1 MPSRLPIQDICAGLLTSVGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPQWLE 109          

Query:  136 DTENLNDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLE 666
            DT    D CRVCR   T ++ L++PC+CTGSIK++HQ+CL+QWLKHS++E+CELCK++FAF PIYS DMP+RLPV  +  GL +SI  A+  W HY+LVA AWL VVPLTACRI + LFTGSVSSLLTLPLDMLST ++  DCL G  VV  TL  F+  +W+REQI+  G P+WLE
Sbjct:    2 DTAEEADICRVCRSEGTQDKPLYHPCVCTGSIKFIHQECLLQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPVQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTQNLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPQWLE 178          

Query:  151 NDFCRVCRCGATLNRALFYPCLCTGSIKYVHQDCLMQWLKHSKREFCELCKYKF----AFAPI 327
             D CR+C C       L  PC CTGS+++VHQ CL QW+K S    CELCKY+F     F P+
Sbjct:   72 QDICRICHCEGDEESPLITPCHCTGSLRFVHQGCLQQWIKSSDTRCCELCKYEFIMETKFKPL 134          

Query:  256 MQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFNLDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLI 1155
            MQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEIRNLDIQNLNNQNDGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFNLDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVF      I H+ I+  +   +I
Sbjct:    1 MQWLKHSKREFCELCKYKFAFAPIYSADMPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEIRNLDIQNLNNQNDGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFNLDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFGIIVIIIVHYNILSQHFVHII 300          

Query:  340 MPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEXXXXXXXXXXXXXXGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFNLDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLI 1155
            MPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEIRNLDIQNLNNQNDGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFNLDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVF      I H+ I+  +   +I
Sbjct:    1 MPTRLPVAILVQGLFSSIKRAVLSWLHYSLVAIAWLLVVPLTACRICRSLFTGSVSSLLTLPLDMLSTDHIFIDCLYGIVVVGLTLGTFVCFMWVREQIMINGGPEWLEIRNLDIQNLNNQNDGIAGNAIVNNVNLLDGARNLLPNVLNALGAGPDDIQDDANWNIEEQMNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFNLDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFGIIVIIIVHYNILSQHFVHII 272          

Query:  847 MNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFNLDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDXXXXXXXXXXXXAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPATFIFMHWTVGVMXXXXXXXXXXXXKEMLRPGIFWFLKNFNDPNFNPIQDM 1593
            MNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFNLDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDGIITTIIGYVIIAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAP TFIFMHWTVGVMYLFYFASFLLLLKEMLRPGIFWFLKNFNDPNFNPIQD+
Sbjct:    1 MNQNFGNENANAIEAVNQENGQAAGNHPQIIGNQGVGNFNLDWGRGGEELTWEKLIGLDGSLFFLEHVFWIVSLNTLFILVFAFCPYHIGHFTIVGFNLTKLISWTKMDGIITTIIGYVIIAFGLLILHRLLKYIRIKCLEKPCHIAGLAFIIIKVALFTILEIGIVPLLCGVWIDICSLSMFNSTLYQRHNLFQYAPTTFIFMHWTVGVMYLFYFASFLLLLKEMLRPGIFWFLKNFNDPNFNPIQDV 249          

Query: 2269 YSLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIF 2709
            + LYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIA  F
Sbjct:   29 FRLYQKFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAQYF 175          

Query: 2284 KFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAPIF 2709
            KFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIA  F
Sbjct:   16 KFLNGDGDIQRFRTRLINGVLILWKLVVLGIVTFVWIPLTLGLLINLCVLSPIRVPLDKSIILSFWENWMFGMMHLKIWVMILLFGPRWWFRERLDIIEQELARRENLRLLHLTEQAGPLVAFVTLAITGPFVFSKTIAQYF 157