Innexin

Overview
NameInnexin
Smed IDSMED30010974
Length (bp)2663
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Innexin (SMED30010974) t-SNE clustered cells

Violin plots show distribution of expression levels for Innexin (SMED30010974) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Innexin (SMED30010974) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Innexin (SMED30010974) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30010974

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30010974h1SMcG0011868 Contig763GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
pharynxSMED30010974 dd_Smed_v4_1120_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30010974 dd_Smed_v4_1120_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30010974 dd_Smed_v4_1120_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30010974 dd_Smed_v4_1120_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30010974 Contig42250uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30010974 Contig42250newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
intestinal phagocyteSMED30010974 dd_Smed_v6_1120_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-13 (Innexin [Source:UniProtKB/TrEMBL;Acc:O44887])

HSP 1 Score: 236.498 bits (602), Expect = 1.053e-69
Identity = 129/386 (33.42%), Postives = 220/386 (56.99%), Query Frame = 2 
Query: 1247 LKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQNSL-FKQRFKNHITISQRNSKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFLF-GFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTVFLSKKSDYMSNEFSALHACNSETC---------SDVYLILRLLETNCGILTTRKITENLLEYYKQPEHLGKYNSLPPNYHEL 2371
            L +  D+D +DR+N ++TP+LL IF++ +  K Y VG+P+QCW+P  F+  WE+YSE++C+++NTY++  +K IP  +  RE +E+ YYQWVPF+LGLQA+LF LPS+ W+ +N+   + +K ++  A  +     + R +       H+  SL  + RF  + +              G YLT+ Y+  K LY++ I+ QFII++ FL  ++ F G  +LS + +G +W+++G FPRVT+CDF +  +G +   ++QCVL+IN+FNEK+Y+F+WFWL  +   T  NL  W  +++        + K    + + FS  ++ N +           SD   I  L++ N G + +  +  ++ + + Q E        P  + E+
Sbjct:   11 LHKQGDDDSIDRLNYYWTPMLLVIFALTLSAKQY-VGQPIQCWIPAQFTGAWEQYSENYCFVQNTYFISPDKYIPDSEIDREGAEIGYYQWVPFILGLQAILFYLPSLFWRLMNFNSGVALKKMLFGAKKADRVDEKARNEAAKSTGAHLYESLTLQSRFAKYTS---------AFTYGGSYLTYLYLFVKFLYLVQIVFQFIILNNFLGTSYTFWGLGILSDILNGREWEESGHFPRVTMCDFEVRVLGNKHRHTVQCVLMINMFNEKVYVFLWFWLVIVGVATFLNLVNWTRKLMFRSARKAHI-KSYLQIEDNFSDDNSRNGQILDKFVDYKLKSDGVFITHLIDNNGGSVFSHDVIVDMWDRFLQDEDNRSQKKQPAEFREI 385
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412])

HSP 1 Score: 233.032 bits (593), Expect = 1.469e-67
Identity = 130/356 (36.52%), Postives = 215/356 (60.39%), Query Frame = 2 
Query: 1262 DEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWK-FLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRN---SKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFL-FGFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTVFLSK--------KSDYMSNEFSALHACNSETCSDVYLILRLLETNCGILTTRKI 2290
            D+DFVD++N +YT  +L  F++++  K Y VG P+QCWVP  F+D  E+Y+E++C+++NTY+VP +++IP E   R N ++ YYQWVPF+L ++A+LF +P ILW+  L W   I+++ LV+ A  +     E + +T++ ++ H+Q+ L     + H      N      CG  + G Y+T  YIG K+LY  N+++QF +++  L +N L +GF LL  L    +W+QTG+FPRVTLCDF +  +G     ++QCVL+IN+FNEKI++F+WFW      +TV N   WI  M +  +   F+ K         +  ++++ +     N+    D   +LR++ T+ G L + ++
Sbjct:   79 DDDFVDKLNYYYTTTILASFALLVSAKQY-VGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDELTNIDRQGHSRSCFSNLQLGANCG-RHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSEL 432
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412])

HSP 1 Score: 232.646 bits (592), Expect = 2.330e-67
Identity = 130/356 (36.52%), Postives = 215/356 (60.39%), Query Frame = 2 
Query: 1262 DEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWK-FLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRN---SKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFL-FGFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTVFLSK--------KSDYMSNEFSALHACNSETCSDVYLILRLLETNCGILTTRKI 2290
            D+DFVD++N +YT  +L  F++++  K Y VG P+QCWVP  F+D  E+Y+E++C+++NTY+VP +++IP E   R N ++ YYQWVPF+L ++A+LF +P ILW+  L W   I+++ LV+ A  +     E + +T++ ++ H+Q+ L     + H      N      CG  + G Y+T  YIG K+LY  N+++QF +++  L +N L +GF LL  L    +W+QTG+FPRVTLCDF +  +G     ++QCVL+IN+FNEKI++F+WFW      +TV N   WI  M +  +   F+ K         +  ++++ +     N+    D   +LR++ T+ G L + ++
Sbjct:   92 DDDFVDKLNYYYTTTILASFALLVSAKQY-VGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDELTNIDRQGHSRSCFSNLQLGANCG-RHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSEL 445
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-9 (Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O01393])

HSP 1 Score: 229.565 bits (584), Expect = 3.669e-67
Identity = 133/365 (36.44%), Postives = 220/365 (60.27%), Query Frame = 2 
Query: 1262 DEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNSKGCGLL----NSGFYLTFCYIGCKILYVLNIIMQFIIVHTFL-KANFLFGFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTVFLSKKSDYMSNEFSALHACNSETC---------SDVYLILRLLETNCGILTTRKITENLLEYY 2314
            D+D +D++N +YT  ++T+F+I++  K Y VG P+QCWVP  F++  E+Y+E++C+++NTY++P    IP     REN ++ YYQWVPFVL L+A+LF +P+I+W+ L+WQ  IH++ LV+ A  S     E R + L  I+ +++ +L  +    H  +S    K   L+    +SG  +TF YI  KILY +NI+ Q  +++TFL   +  +G ++L+ L +G +W+++G FPRVTLCDF +  +G     ++QCVL+IN+FNEKI++F+WFW   L   T+ +LF WI   V+  +   F+ K   Y++         +S++           D   +LR++ T+ G L   ++ + L   Y
Sbjct:   20 DDDIIDKLNYYYTTAIITVFAILVSAKQY-VGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLHDYIPHNYAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVK----HQVMSGNRLKLLNLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGK---YLTG-IEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNY 375
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412])

HSP 1 Score: 229.18 bits (583), Expect = 6.918e-67
Identity = 128/358 (35.75%), Postives = 217/358 (60.61%), Query Frame = 2 
Query: 1262 DEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWK-FLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQN-----SLFKQRFKNHITISQRNSKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFL-FGFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTVFLSK--------KSDYMSNEFSALHACNSETCSDVYLILRLLETNCGILTTRKI 2290
            D+DFVD++N +YT  +L  F++++  K Y VG P+QCWVP  F+D  E+Y+E++C+++NTY+VP +++IP E   R N ++ YYQWVPF+L ++A+LF +P ILW+  L W   I+++ LV+ A  +     E + +T++ ++ H+Q+     ++ +Q        + +    CG  + G Y+T  YIG K+LY  N+++QF +++  L +N L +GF LL  L    +W+QTG+FPRVTLCDF +  +G     ++QCVL+IN+FNEKI++F+WFW      +TV N   WI  M +  +   F+ K         +  ++++ +     N+    D   +LR++ T+ G L + ++
Sbjct:   18 DDDFVDKLNYYYTTTILASFALLVSAKQY-VGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDEVQLTNIDRQGHSRSCFSNLQLGANCG-RHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSEL 373
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: shakB (gene:FBgn0085387 transcript:FBtr0112571)

HSP 1 Score: 78.1814 bits (191), Expect = 5.947e-15
Identity = 76/299 (25.42%), Postives = 135/299 (45.15%), Query Frame = 2 
Query: 1208 LLTKLQGIKLTSHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYY------------VPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQ-GRIHIKPL-VKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNSKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFL-FGFKLLSTLASGSDWQQTGL---FPRVTLCD-FTIPRVGQELHTSMQCVLVINLFNEK 2047
            +L   +G+K    +  +  +  V R++   T ++L  FS++I T+ Y VG P+ C   VH  D  E    ++C+I++TY             VP      ++    +    +YYQWV F L  QA+LF  P  LWK  +W+ G+IH   + +   + S  EK + +   L  + E++       R+ N                   +  + Y  C++L ++N+I Q  +++ F    F+ FG K++  + +  + +   +   FPR+T C  F     G+       C+L +N+ NEK
Sbjct:    1 MLDIFRGLKNLVKVSHVKTDSIVFRLHYSITVMILMSFSLIITTRQY-VGNPIDC---VHTKDIPEDVLNTYCWIQSTYTLKSLFLKKQGVSVPYPGIGNSDGDPADKKHYKYYQWVCFCLFFQAILFYTPRWLWK--SWEGGKIHALIMDLDIGICSEAEKKQKKKLLLDYLWENL-------RYHN-------------------WWAYRYYVCELLALINVIGQMFLMNRFFDGEFITFGLKVIDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICILPLNVVNEK 267
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: shakB (gene:FBgn0085387 transcript:FBtr0112570)

HSP 1 Score: 76.2554 bits (186), Expect = 2.196e-14
Identity = 79/291 (27.15%), Postives = 130/291 (44.67%), Query Frame = 2 
Query: 1235 LTSHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYV------PREKEIPTEKTMRENSE-------LQYYQWVPFVLGLQAVLFLLPSILWKFLNWQ-GRIHIKPL-VKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNSKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFL-FGFKLLSTLASGSDWQQTGL---FPRVTLCD-FTIPRVGQELHTSMQCVLVINLFNEK 2047
            + SH+K  S    V R++   T +LL  FSI + T+ Y VG P+ C   VH  D  E    ++C+I +TY V       +  E+P                  +YYQWV F L  QA+LF  P  LWK  +W+ G+IH   + +   + S  EK + +   L  + E++       R+ N                   +  + Y  C++L ++N+I Q  +++ F    F+ FG K++  + +  + +   +   FPR+T C  F     G+       C+L +N+ NEK
Sbjct:    1 MVSHVKIDSP---VFRLHTNATVILLITFSIAVTTRQY-VGNPIDC---VHTRDIPEDVLNTYCWIHSTYTVVDAFMKKQGSEVPFPGVHNSQGRGPLTIKHTKYYQWVAFTLFFQAILFYTPRWLWK--SWEGGKIHALIMDLDIGICSEAEKKQKKKLLLDYLWENL-------RYHN-------------------WWAYRYYVCELLALINVIGQMFLMNRFFDGEFITFGLKVIDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICILPLNVVNEK 256
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: shakB (gene:FBgn0085387 transcript:FBtr0309369)

HSP 1 Score: 75.485 bits (184), Expect = 4.843e-14
Identity = 76/289 (26.30%), Postives = 128/289 (44.29%), Query Frame = 2 
Query: 1241 SHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYV------PREKEIPTEKTMRENSE-------LQYYQWVPFVLGLQAVLFLLPSILWKFLNWQ-GRIHIKPL-VKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNSKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFL-FGFKLLSTLASGSDWQQTGL---FPRVTLCD-FTIPRVGQELHTSMQCVLVINLFNEK 2047
            S +  +  +  V R++   T +LL  FSI + T+ Y VG P+ C   VH  D  E    ++C+I +TY V       +  E+P                  +YYQWV F L  QA+LF  P  LWK  +W+ G+IH   + +   + S  EK + +   L  + E++       R+ N                   +  + Y  C++L ++N+I Q  +++ F    F+ FG K++  + +  + +   +   FPR+T C  F     G+       C+L +N+ NEK
Sbjct:   16 SSVSHVKIDSPVFRLHTNATVILLITFSIAVTTRQY-VGNPIDC---VHTRDIPEDVLNTYCWIHSTYTVVDAFMKKQGSEVPFPGVHNSQGRGPLTIKHTKYYQWVAFTLFFQAILFYTPRWLWK--SWEGGKIHALIMDLDIGICSEAEKKQKKKLLLDYLWENL-------RYHN-------------------WWAYRYYVCELLALINVIGQMFLMNRFFDGEFITFGLKVIDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICILPLNVVNEK 272
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: shakB (gene:FBgn0085387 transcript:FBtr0309370)

HSP 1 Score: 75.485 bits (184), Expect = 4.843e-14
Identity = 76/289 (26.30%), Postives = 128/289 (44.29%), Query Frame = 2 
Query: 1241 SHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYV------PREKEIPTEKTMRENSE-------LQYYQWVPFVLGLQAVLFLLPSILWKFLNWQ-GRIHIKPL-VKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNSKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFL-FGFKLLSTLASGSDWQQTGL---FPRVTLCD-FTIPRVGQELHTSMQCVLVINLFNEK 2047
            S +  +  +  V R++   T +LL  FSI + T+ Y VG P+ C   VH  D  E    ++C+I +TY V       +  E+P                  +YYQWV F L  QA+LF  P  LWK  +W+ G+IH   + +   + S  EK + +   L  + E++       R+ N                   +  + Y  C++L ++N+I Q  +++ F    F+ FG K++  + +  + +   +   FPR+T C  F     G+       C+L +N+ NEK
Sbjct:   16 SSVSHVKIDSPVFRLHTNATVILLITFSIAVTTRQY-VGNPIDC---VHTRDIPEDVLNTYCWIHSTYTVVDAFMKKQGSEVPFPGVHNSQGRGPLTIKHTKYYQWVAFTLFFQAILFYTPRWLWK--SWEGGKIHALIMDLDIGICSEAEKKQKKKLLLDYLWENL-------RYHN-------------------WWAYRYYVCELLALINVIGQMFLMNRFFDGEFITFGLKVIDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICILPLNVVNEK 272
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: shakB (gene:FBgn0085387 transcript:FBtr0342859)

HSP 1 Score: 75.485 bits (184), Expect = 4.843e-14
Identity = 76/289 (26.30%), Postives = 128/289 (44.29%), Query Frame = 2 
Query: 1241 SHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYV------PREKEIPTEKTMRENSE-------LQYYQWVPFVLGLQAVLFLLPSILWKFLNWQ-GRIHIKPL-VKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNSKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFL-FGFKLLSTLASGSDWQQTGL---FPRVTLCD-FTIPRVGQELHTSMQCVLVINLFNEK 2047
            S +  +  +  V R++   T +LL  FSI + T+ Y VG P+ C   VH  D  E    ++C+I +TY V       +  E+P                  +YYQWV F L  QA+LF  P  LWK  +W+ G+IH   + +   + S  EK + +   L  + E++       R+ N                   +  + Y  C++L ++N+I Q  +++ F    F+ FG K++  + +  + +   +   FPR+T C  F     G+       C+L +N+ NEK
Sbjct:   16 SSVSHVKIDSPVFRLHTNATVILLITFSIAVTTRQY-VGNPIDC---VHTRDIPEDVLNTYCWIHSTYTVVDAFMKKQGSEVPFPGVHNSQGRGPLTIKHTKYYQWVAFTLFFQAILFYTPRWLWK--SWEGGKIHALIMDLDIGICSEAEKKQKKKLLLDYLWENL-------RYHN-------------------WWAYRYYVCELLALINVIGQMFLMNRFFDGEFITFGLKVIDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICILPLNVVNEK 272
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O01393|UNC9_CAEEL (Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN=unc-9 PE=1 SV=1)

HSP 1 Score: 229.565 bits (584), Expect = 4.667e-66
Identity = 133/365 (36.44%), Postives = 220/365 (60.27%), Query Frame = 2 
Query: 1262 DEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNSKGCGLL----NSGFYLTFCYIGCKILYVLNIIMQFIIVHTFL-KANFLFGFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTVFLSKKSDYMSNEFSALHACNSETC---------SDVYLILRLLETNCGILTTRKITENLLEYY 2314
            D+D +D++N +YT  ++T+F+I++  K Y VG P+QCWVP  F++  E+Y+E++C+++NTY++P    IP     REN ++ YYQWVPFVL L+A+LF +P+I+W+ L+WQ  IH++ LV+ A  S     E R + L  I+ +++ +L  +    H  +S    K   L+    +SG  +TF YI  KILY +NI+ Q  +++TFL   +  +G ++L+ L +G +W+++G FPRVTLCDF +  +G     ++QCVL+IN+FNEKI++F+WFW   L   T+ +LF WI   V+  +   F+ K   Y++         +S++           D   +LR++ T+ G L   ++ + L   Y
Sbjct:   20 DDDIIDKLNYYYTTAIITVFAILVSAKQY-VGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLHDYIPHNYAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVK----HQVMSGNRLKLLNLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGK---YLTG-IEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNY 375
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q03412|UNC7_CAEEL (Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN=unc-7 PE=1 SV=1)

HSP 1 Score: 229.18 bits (583), Expect = 1.981e-64
Identity = 128/358 (35.75%), Postives = 217/358 (60.61%), Query Frame = 2 
Query: 1262 DEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWK-FLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQN-----SLFKQRFKNHITISQRNSKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFL-FGFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTVFLSK--------KSDYMSNEFSALHACNSETCSDVYLILRLLETNCGILTTRKI 2290
            D+DFVD++N +YT  +L  F++++  K Y VG P+QCWVP  F+D  E+Y+E++C+++NTY+VP +++IP E   R N ++ YYQWVPF+L ++A+LF +P ILW+  L W   I+++ LV+ A  +     E + +T++ ++ H+Q+     ++ +Q        + +    CG  + G Y+T  YIG K+LY  N+++QF +++  L +N L +GF LL  L    +W+QTG+FPRVTLCDF +  +G     ++QCVL+IN+FNEKI++F+WFW      +TV N   WI  M +  +   F+ K         +  ++++ +     N+    D   +LR++ T+ G L + ++
Sbjct:  138 DDDFVDKLNYYYTTTILASFALLVSAKQY-VGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDEVQLTNIDRQGHSRSCFSNLQLGANCG-RHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSEL 493
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q19746|INX3_CAEEL (Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx-3 PE=1 SV=2)

HSP 1 Score: 213.386 bits (542), Expect = 8.239e-60
Identity = 143/422 (33.89%), Postives = 226/422 (53.55%), Query Frame = 2 
Query: 1235 LTSHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHIT--ISQRNSKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFL-KANFLFGFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKK----LTVFLSKKSDYMSNEFSALHA-CNSETCSDVYLILRLLETNCGILTTRKITENLLEYYKQPEHLGKYNSLPPNYHELDKNDNHXXXXXXXXXXGLHIAYIYISDCLSLKHPN 2476
            L+   K  + +D VDR++   T  LL  FSI++  K Y VG  +QCW+P+ F  GWE+Y+E +C+I+NT+++P   EIP +   R+ +E+ YYQWVP VL +QA +F LPS +W  L  Q  +    ++  A     +  E R K ++K+ + I + L   R KN        R  KG G + S       YI  K++Y+ N+ +QFII++ FL    FL+GF   + L +G +WQ +G+FPRVTLCDF++ ++      ++QCVL+IN+FNEKIY+FIWFW  F+   T  N    I R+         +   LS   +   +E + + +  N+    D  L++R ++ + G + T++I E L +  K  E+L          H  D +  HS  S+       H  ++Y  + + L  P+
Sbjct:   11 LSETFKPKTFDDAVDRLSYVTTATLLAFFSIMVSCKQY-VGSAIQCWMPMEFKGGWEQYAEDYCFIQNTFFIPERSEIPGDVEDRQKAEIGYYQWVPIVLAIQAFMFYLPSWIWSSLYKQCGLDFPSVISEAEALRSQDSETRTKGVNKLVDFIGDIL-DTRSKNEYGRFYCYRFGKGLGSMTS-----MLYICIKLMYLANVFVQFIILNKFLGNETFLWGFHTFADLYAGREWQDSGVFPRVTLCDFSVRKLANVHRYTVQCVLMINMFNEKIYLFIWFWFVFVLITTFINTLCTIYRLSFDSSRHNYIRSLLSGPVNNFKDEKAMIASFANNGLKQDGVLLMRFIDDHAGAMVTKEICEELFK--KHGENLQ---------HNRDFHHGHSTKSTSPGLEEGHHEHLYTPEKMKLMAPD 414
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q27295|EAT5_CAEEL (Innexin eat-5 OS=Caenorhabditis elegans OX=6239 GN=eat-5 PE=2 SV=1)

HSP 1 Score: 195.282 bits (495), Expect = 2.319e-53
Identity = 98/270 (36.30%), Postives = 157/270 (58.15%), Query Frame = 2 
Query: 1241 SHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNSKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFLF-GFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEK 2047
            S +K   D+   DR+N +Y+ L++   S+ I  + Y VG PLQCWVP  F+  WE+Y+E +C++ NTY+V    ++P     R + +L YYQW PF++ ++A  F LP I W  L+ +  I+I  LV+ A  +   + E+R K +  I  HI N+L K+R +   T   +  +  G +  G Y+T  Y+  K++Y+ N  +QF   + FL  N  + G ++L  +  G+DW+ +G FPR+ +CDF +  +G     S+QCVL +N+FNEK
Sbjct:    9 SMVKPRLDDLGTDRLNYYYSTLIIMGMSLTITARQY-VGSPLQCWVPAQFTKAWEQYAEDYCFVYNTYWVKPNDKVPLTVEERVSQQLIYYQWAPFIMAIEAAFFYLPVIFWSMLSTKSGINIIKLVETAQKAEGAESEERKKQIDIICRHISNNLRKRRNEEETTKMAKIQRIFG-MQHGKYITNVYLVTKLIYMTNSFLQFYSTNKFLGQNDPYWGMRILDDILKGTDWEHSGNFPRIAMCDFQVRVLGNLQRYSIQCVLTLNMFNEK 276
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|A8WVX4|INX19_CAEBR (Innexin-19 OS=Caenorhabditis briggsae OX=6238 GN=inx-19 PE=3 SV=3)

HSP 1 Score: 193.356 bits (490), Expect = 1.774e-52
Identity = 126/396 (31.82%), Postives = 206/396 (52.02%), Query Frame = 2 
Query: 1241 SHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAV-LSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNSK-GCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKAN--FLFGFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTVFLSKKSDYM--------SNEFSALHACNSETC------------------------SDVYLILRLLETNCGILTTRKITENLLEYYKQ 2320
            S L    D+D VDR+N +YTPL+L +  +VI  K Y  G P++CWV  H  +  E+Y ES+C+I+NTY++P  + +P + T RE  ++ YYQWVPF+L  +A++F LP I W+  ++Q  ++I+ L+  A    +   Y DR K +  I+ +  ++L  Q     I      ++       SG  ++  Y   K+LY +N++ QF I++  LK++    FGF++LS + +G  W +TG FPRVTLCDF +  +      ++QC L+IN+ NEK++ F+W W   L  IT  +   WIA   +        S+K DY+        S+E+  L     +                          SD  L+LR++  + G +   ++  NL + Y++
Sbjct:   13 SALSVRGDDDAVDRLNYYYTPLILAVCCLVISAKQY-GGTPIECWVNPHSRESMEEYIESYCWIQNTYWIPMYENVPDDHTAREEKQIGYYQWVPFILIAEALMFSLPCIFWRLCSFQSGLNIQTLINAACDAQALLDYSDRQKAVEAITCNFVDNLDLQSPNGRIRARGWIARIKFSRFLSGQCISIVYSFTKLLYSVNVVAQFFILNACLKSSEFVFFGFQVLSDIWAGRPWTETGHFPRVTLCDFEVRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIH-------SEKVDYVMKFIQIAESSEYKKLQKFEKDATVERLYTVIAFAPHLLDSFVSDFLKSDGILMLRMISNHAGDMIVVQLVRNLWQEYRE 400
[Close]
BLAST of Innexin vs. TrEMBL
Match: Q2L6M8 (Innexin OS=Dugesia japonica OX=6161 GN=inx7 PE=3 SV=1)

HSP 1 Score: 572.392 bits (1474), Expect = 0.000e+0
Identity = 284/399 (71.18%), Postives = 337/399 (84.46%), Query Frame = 2 
Query: 1196 MDKGLLTKLQGIKLTSHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNSKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFLFGFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTVFLSKKSDYMSN--EFSALHACNSETCSDVYLILRLLETNCGILTTRKITENLLEYYKQPEHLGKYNSLPPNYHELDKNDN 2386
            MDKGLL+ LQ IKLTSHLKRISD+DFVDRINNFYTPL+LTI +IVICTKSYIVGEPLQCWVPVHFS GWEK+SESWCYIKNTYYVP+ KE+PTEK MRE+SELQYYQWVPFVLGLQAVLFL PSI WKF NWQGR+HIKPL++R V SS+E  + R  TL +I+EHI+NSLFK ++ NH T+S  N K CG +NSGFYLTFCY+  K+LY+ NII+QFIIVH FLKA+F FGF LL+ L+SGSDWQ+TGLFPRVT+CDFT PR+GQ+L T+MQCVLVINLFNEKIYIF+WFWLAFLF IT+ N F+W+ RM+ G+KL+ F+S KS+Y  N    S + +C SE  +DVYL+LR++++NCG++TTRKITE L+ +YK      KYNSL PNYHELDK DN
Sbjct:    1 MDKGLLSTLQKIKLTSHLKRISDDDFVDRINNFYTPLILTILTIVICTKSYIVGEPLQCWVPVHFSGGWEKFSESWCYIKNTYYVPKYKELPTEKDMREHSELQYYQWVPFVLGLQAVLFLFPSIFWKFSNWQGRLHIKPLMQRGVKSSFEVGDSRSTTLKEIAEHIRNSLFKSQYGNHPTLSAGNDKCCGFINSGFYLTFCYLISKLLYLTNIIIQFIIVHRFLKADFFFGFNLLTKLSSGSDWQETGLFPRVTMCDFTTPRIGQDLPTTMQCVLVINLFNEKIYIFLWFWLAFLFLITLINSFIWLIRMLFGRKLSRFVSTKSNYAKNPDHVSNMMSCESEANTDVYLVLRMIDSNCGLMTTRKITEYLISFYKSSPRNDKYNSLSPNYHELDKTDN 399
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A267DW92 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 282.722 bits (722), Expect = 5.584e-83
Identity = 157/387 (40.57%), Postives = 233/387 (60.21%), Query Frame = 2 
Query: 1196 MDKGLLTKLQGIKLTSHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNS-----KGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFLF-GFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTVFLSK-------KSDYMSNEFSALHACNSETCSDVYLILRLLETNCGILTTRKITENLLEYYK 2317
            MD G   K++ +K TS   RISDED VDRIN++YTP+++   S +I TK Y+VG+P+QCW+P  F DGWE+++E++C++KNTYYVP  + IP++K  R   EL YYQWVPFVL LQA+LF LPS +WK LNWQ  IHI  LV  A+    +  + R + +  ++ HI+ ++ KQR + +  I +          CG   +G YLT  Y+G K+L++ N++ QF ++++FL  ++ F G+++L+ L +  DW  TG FPRVTLCDF I  +G     ++QCVLV+NLFNEK YIF+WF   F+  IT+ +   W    VL K+    + K       +   M  +F   H       +D   +LR++  N G      + + L + Y+
Sbjct:    1 MDTGFFDKVKELKFTSRKHRISDEDAVDRINSYYTPIIIIFISTIIGTKMYLVGDPVQCWIPPEFKDGWEQFAENYCWVKNTYYVPENESIPSDKLDRSREELTYYQWVPFVLALQALLFYLPSAIWKLLNWQSGIHISDLVSTALNCLEDDEQKRQEKVALLTRHIELTIVKQRTQKYGLIVRTKRLIFRILFCGYTKTGNYLTMMYLGIKLLFIANVVGQFFLLNSFLGTDYKFYGWEVLNDLINNRDWHHTGHFPRVTLCDFDIRVLGNMHPRTLQCVLVVNLFNEKAYIFLWFLFVFVSIITIVDAIAWFLWTVLSKRRYATIKKYITPADQQERRMLRDFLEEH-----LRADGAFVLRIISKNAGDPVVSDVVKQLWDSYR 382
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A267DF38 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 281.567 bits (719), Expect = 1.863e-82
Identity = 156/387 (40.31%), Postives = 233/387 (60.21%), Query Frame = 2 
Query: 1196 MDKGLLTKLQGIKLTSHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNS-----KGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFLF-GFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTVFLSK-------KSDYMSNEFSALHACNSETCSDVYLILRLLETNCGILTTRKITENLLEYYK 2317
            MD G   K++ +K TS   RISDED VDRIN++YTP+++   S +I TK Y+VG+P+QCW+P  F DGWE+++E++C++KNTYYVP  + IP++K  R   EL YYQWVPFVL LQA+LF LPS +WK LNWQ  IHI  LV  A+    +  + R + +  ++ HI+ ++ KQR + +  I +          CG   +G YLT  Y+G K+L++ N++ QF ++++FL  ++ F G+++L+ L +  DW  TG FPRVTLCDF I  +G     ++QCVLV+NLFNEK YIF+WF   F+  IT+ +   W    +L K+    + K       +   M  +F   H       +D   +LR++  N G      + + L + Y+
Sbjct:    1 MDTGFFDKVKELKFTSRKHRISDEDAVDRINSYYTPIIIIFISTIIGTKMYLVGDPVQCWIPPEFKDGWEQFAENYCWVKNTYYVPENESIPSDKLDRSREELTYYQWVPFVLALQALLFYLPSAIWKLLNWQSGIHISDLVSTALNCLEDDKQKRQEKVALLTRHIELTIVKQRTQKYGLIVRTKRLIFRILFCGYTKTGNYLTMMYLGIKLLFIANVVGQFFLLNSFLGTDYKFYGWEVLNDLINNRDWHHTGHFPRVTLCDFDIRVLGNMHPRTLQCVLVVNLFNEKAYIFLWFLFVFVSIITIVDAIAWFLWTLLSKRRYATIKKYITPADQQERRMLRDFLEEHL-----RADGAFVLRIISKNAGDPVVSDVVKQLWDSYR 382
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A1I8J2L7 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 281.567 bits (719), Expect = 1.863e-82
Identity = 156/387 (40.31%), Postives = 233/387 (60.21%), Query Frame = 2 
Query: 1196 MDKGLLTKLQGIKLTSHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNS-----KGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFLF-GFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTVFLSK-------KSDYMSNEFSALHACNSETCSDVYLILRLLETNCGILTTRKITENLLEYYK 2317
            MD G   K++ +K TS   RISDED VDRIN++YTP+++   S +I TK Y+VG+P+QCW+P  F DGWE+++E++C++KNTYYVP  + IP++K  R   EL YYQWVPFVL LQA+LF LPS +WK LNWQ  IHI  LV  A+    +  + R + +  ++ HI+ ++ KQR + +  I +          CG   +G YLT  Y+G K+L++ N++ QF ++++FL  ++ F G+++L+ L +  DW  TG FPRVTLCDF I  +G     ++QCVLV+NLFNEK YIF+WF   F+  IT+ +   W    +L K+    + K       +   M  +F   H       +D   +LR++  N G      + + L + Y+
Sbjct:    1 MDTGFFDKVKELKFTSRKHRISDEDAVDRINSYYTPIIIIFISTIIGTKMYLVGDPVQCWIPPEFKDGWEQFAENYCWVKNTYYVPENESIPSDKLDRSREELTYYQWVPFVLALQALLFYLPSAIWKLLNWQSGIHISDLVSTALNCLEDDKQKRQEKVALLTRHIELTIVKQRTQKYGLIVRTKRLIFRILFCGYTKTGNYLTMMYLGIKLLFIANVVGQFFLLNSFLGTDYKFYGWEVLNDLINNRDWHHTGHFPRVTLCDFDIRVLGNMHPRTLQCVLVVNLFNEKAYIFLWFLFVFVSIITIVDAIAWFLWTLLSKRRYATIKKYITPADQQERRMLRDFLEEH-----LRADGAFVLRIISKNAGDPVVSDVVKQLWDSYR 382
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A0N4UAF6 (Innexin OS=Dracunculus medinensis OX=318479 GN=inx PE=3 SV=1)

HSP 1 Score: 271.937 bits (694), Expect = 4.492e-79
Identity = 154/389 (39.59%), Postives = 235/389 (60.41%), Query Frame = 2 
Query: 1247 LKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNSKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFLF-GFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTVFLS---KKSDYMSNEF-SALHACNSETC-SDVYLILRLLETNCGILTTRKITENLLEYYKQPE--HLGKYNSLPPNYHELDKNDNH 2389
            LK   D+D +DR+N +YTP+L  IF++ +  K Y VG+P+QCW+P  F+  WE+YSE++C+I+NTY++P    IP +   RE+ E+ YYQWVPF+LGLQ +LF LP+++WK  NWQ  I +K +V  +   S  + E R  ++  +S HI +SL     K    +S+R      +L  G YLT  Y+  K++Y+L  IMQFII++ FL  N+ F GF++L  LA G +WQ++G FPRVT+CDF +  +G +   ++QCVL+IN+FNEK+Y+F+W+W+  +   T+G+LF WI   +   +   F+S   +  D + +E   A+      T  +D   ILR++ +N G L T  I   L + Y + E        SL  N  + D  +NH
Sbjct:   11 LKPEFDDDAIDRLNYYYTPMLFVIFALTLSAKQY-VGQPIQCWIPAQFTGAWEQYSENYCFIQNTYFLPLNHYIPRDLEERESREIGYYQWVPFILGLQGILFYLPNLIWKLFNWQSGIAVKGIVTMSQDVSNMQTEKRNDSVAVVSSHIYDSL-----KTQQKLSRRGLI-AAILQKGSYLTILYLFIKLVYILQAIMQFIILNNFLGTNYTFWGFEILRDLAHGREWQESGHFPRVTMCDFDVRVLGNKHRHTVQCVLMINMFNEKVYLFLWWWILLVLIATIGSLFYWIIVGLSKAQQRSFISQYLRVYDLLDDESRGAVDKFVQRTLRNDGVFILRIVSSNAGDLITTDIVAALWKMYLEDEKNRQAHRPSLIGNAPKFDDENNH 392
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000055733.1 (SMESG000055733.1)

HSP 1 Score: 784.637 bits (2025), Expect = 0.000e+0
Identity = 398/398 (100.00%), Postives = 398/398 (100.00%), Query Frame = 2 
Query: 1196 MDKGLLTKLQGIKLTSHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNSKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFLFGFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTVFLSKKSDYMSNEFSALHACNSETCSDVYLILRLLETNCGILTTRKITENLLEYYKQPEHLGKYNSLPPNYHELDKNDNH 2389
            MDKGLLTKLQGIKLTSHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNSKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFLFGFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKIYIFIWFWLAFLFFITVGNLFVWIARMVLGKKLTVFLSKKSDYMSNEFSALHACNSETCSDVYLILRLLETNCGILTTRKITENLLEYYKQPEHLGKYNSLPPNYHELDKNDNH
Sbjct:    1 MDKGLLTKLQGIKLTSHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNSKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFLFGFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKIYIFIWFWLAFLFFITVGNLFVWIARMVLGKKLTVFLSKKSDYMSNEFSALHACNSETCSDVYLILRLLETNCGILTTRKITENLLEYYKQPEHLGKYNSLPPNYHELDKNDNH 398
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000056430.1 (SMESG000056430.1)

HSP 1 Score: 235.728 bits (600), Expect = 5.311e-69
Identity = 147/409 (35.94%), Postives = 231/409 (56.48%), Query Frame = 2 
Query: 1250 KRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAV----------------LSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITI-SQRNSKG-----------CGLLNS--GFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANF-LFGFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTV---FLSKK-SDYMSNEFSALHACNSETC-SDVYLILRLLETNCGILTTRKITENLLEYYKQPEHLGKYNSLPPNYHE 2368
            +R  D+DF DRIN++YT ++L I +I I TK Y+  + + CW+PV FS  W +Y+E++C+I+NTYY+P + E+P     R  S+L YYQWVP+VL LQ  LF  P   W+ +NWQ  I+I+ L+ +A+                  +    E +V     I   +   +    +   ++I S+ NSKG           CG  +   GFYL   YI  K+LY++N++ Q  ++++F+  ++ LFGF++L  LA G+DW+ TG FPR+TLCDF I  +GQ  + ++QCVL INLFNEKIYIFIWFW+  +  ++V +LF W+ RM+  ++       L K+  ++ + + + L     E   +D   ++ L+  N G L T+++ + +   YK+        SL  NY E
Sbjct:   16 RRGRDDDFFDRINHWYTSIVLVIMAIFISTKQYL-NDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKIYIFIWFWIFIVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKM--SLDNNYPE 421
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000065921.1 (SMESG000065921.1)

HSP 1 Score: 220.32 bits (560), Expect = 3.632e-64
Identity = 135/370 (36.49%), Postives = 210/370 (56.76%), Query Frame = 2 
Query: 1196 MDKGLLTKLQGIKLTSHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAVLSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNSKGCGLLNSGFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFL-FGFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTVFLSKKSDYMSNEFSALH-ACNSETCSDVYLILRLLETNC-GILTTRKITE 2296
            M+  +   +   KL S   R+SD DFVD  N+++ PL   +FS+ IC K Y++G+PLQCWVP  +SD WE+Y+E++C+++NTY+V   + +  +++    SE+ YYQWVPFVL LQ ++F LP   W+  NW   + I  L++ A+ +S          + K+ E  Q+S F + + N   I ++           ++L  CYI  KILY+LN+I+QF I+ +FL  +F+ FG ++L+   +   W +TG FPRVT C FTI  + +  + ++QCVLV+N+  EK+YI +WF L FL F+ + N   W+  MV  +K                  +H     +  SD   +LRLL+ NC G+  +  ITE
Sbjct:    1 MNSDIFGFVSSFKLASRKLRVSDSDFVDVFNHYFLPLTFCLFSLAICAKQYLIGDPLQCWVPKEYSDAWEQYAENYCWVENTYFVRSNQTLKKDQS----SEIIYYQWVPFVLILQGLMFYLPHYFWRLTNWMSGVDILHLMRLALDASTSS-----TNITKLVERFQDS-FLESYGNKFVIKRK-----------YFLCVCYIIMKILYLLNLILQFQIISSFLNLDFMTFGVRILNEFNNNIFWDKTGDFPRVTFCHFTIRTINENQNYTVQCVLVVNMLIEKLYITLWFILVFLLFLNLFNFANWMIWMVSKRKAV-------------HDGVHTGIWDQMNSDSLFVLRLLKKNCLGLSYSSFITE 336
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000056430.1 (SMESG000056430.1)

HSP 1 Score: 221.476 bits (563), Expect = 1.015e-63
Identity = 153/429 (35.66%), Postives = 241/429 (56.18%), Query Frame = 2 
Query: 1199 DKGLLTKLQGIKLTSHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVP---REKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAV----------------LSSYEKYEDRVKTLHKISEHIQNSLFKQRFKNHITI-SQRNSKG-----------CGLLNS--GFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANF-LFGFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTV---FLSKK-SDYMSNEFSALHACNSETC-SDVYLILRLLETNCGILTTRKITENLLEYYKQPEHLGKYNSLPPNYHE 2368
            + G L  +QG+++ S LK   D+D+ DR+++ +T L L I S++I +  Y VG P+ CWVP  FS  W+KY+ ++C+IKNTY VP   ++  IP + + R   E+ YYQWVP VL  QA+LF  PSI+W+ LNW   I+I+ L+ +A+                  +    E +V     I   +   +    +   ++I S+ NSKG           CG  +   GFYL   YI  K+LY++N++ Q  ++++F+  ++ LFGF++L  LA G+DW+ TG FPR+TLCDF I  +GQ  + ++QCVL INLFNEKIYIFIWFW+  +  ++V +LF W+ RM+  ++       L K+  ++ + + + L     E   +D   ++ L+  N G L T+++ + +   YK+        SL  NY E
Sbjct:    4 NTGFLAFVQGLEIFS-LKTRRDDDYCDRLSHHHTALFLLITSVLISSNQY-VGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIP-KPSERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKIYIFIWFWIFIVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKM--SLDNNYPE 427
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000035987.1 (SMESG000035987.1)

HSP 1 Score: 223.016 bits (567), Expect = 1.017e-63
Identity = 144/368 (39.13%), Postives = 214/368 (58.15%), Query Frame = 2 
Query: 1262 DEDFVDRINNFYTPLLLTIFSIVICTKSYIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYV-PREKEIPTEKTMRENSELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAVLSSYEK-YEDRVKTLHKISEHIQNSLFKQR-FKNHITISQRNSKG---CGLLNS--GFYLTFCYIGCKILYVLNIIMQFIIVHTFLKANFLF-GFKLLSTLASGSDWQQTGLFPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKXXXXXXXXXXXXXXXTVGNLFVWIARMVLGKKLTVFLS-----KKSDYMSNEFSALHA-CNSETCSDVYLILRLLETNCGILTTRKITENLLEYYKQ 2320
            D+D  DR N+F+T +LL  FS+V+ T+ Y VG+P+ CWVP  F+   E+Y+ES C++ +TY++ P +  IP     RE  ++ YYQWVPF+L LQA+LF  P  +W+ LNWQ  ++I  ++  A  +   K YE R   L  I+ HI ++L  QR ++N  T+  R+      C       G YL   Y  CK LY+LN+I QF +++ FL  N+ F G  L+  L+ G++W ++G FPRVT+CDF I ++  +   ++QCVL INLFNEKI+IF+WFW  F+  ITV +   W ++ V   +   F+      K +   + +   L+A  +     D   ILRLL  NCG L   +ITE L   +K+
Sbjct:   22 DDDQSDRFNHFFTTILLVCFSLVVSTRQY-VGKPIACWVPTEFTSSQEEYAESICWVSSTYFINPYQGSIPENTQQREEKKILYYQWVPFILMLQAILFNFPCCVWRLLNWQSGLNISAIIDIAGDTEMIKDYEQRKANLDFITRHIDDTLRIQREYRNGCTVQCRHCLAQHFCMWFGRRYGNYLVCVYTICKSLYILNVIGQFFLMNRFLGTNYTFYGLDLIYQLSIGNEWTESGNFPRVTMCDFNIRKLANQHRYTVQCVLPINLFNEKIFIFLWFWFVFIAIITVHSFIHWTSKSVCRIQRYNFIRKFLVLKDALQEAGDRKKLYAFIDLFLQQDGVFILRLLALNCGDLIAAEITEYLWCRFKE 388
The following BLAST results are available for this feature:
BLAST of Innexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
inx-131.053e-6933.42Innexin [Source:UniProtKB/TrEMBL;Acc:O44887][more]
unc-71.469e-6736.52Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q0... [more]
unc-72.330e-6736.52Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q0... [more]
unc-93.669e-6736.44Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O0... [more]
unc-76.918e-6735.75Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q0... [more]
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BLAST of Innexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
shakB5.947e-1525.42gene:FBgn0085387 transcript:FBtr0112571[more]
shakB2.196e-1427.15gene:FBgn0085387 transcript:FBtr0112570[more]
shakB4.843e-1426.30gene:FBgn0085387 transcript:FBtr0309369[more]
shakB4.843e-1426.30gene:FBgn0085387 transcript:FBtr0309370[more]
shakB4.843e-1426.30gene:FBgn0085387 transcript:FBtr0342859[more]
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BLAST of Innexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O01393|UNC9_CAEEL4.667e-6636.44Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q03412|UNC7_CAEEL1.981e-6435.75Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q19746|INX3_CAEEL8.239e-6033.89Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx... [more]
sp|Q27295|EAT5_CAEEL2.319e-5336.30Innexin eat-5 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|A8WVX4|INX19_CAEBR1.774e-5231.82Innexin-19 OS=Caenorhabditis briggsae OX=6238 GN=i... [more]
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BLAST of Innexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
Q2L6M80.000e+071.18Innexin OS=Dugesia japonica OX=6161 GN=inx7 PE=3 S... [more]
A0A267DW925.584e-8340.57Innexin OS=Macrostomum lignano OX=282301 GN=inx PE... [more]
A0A267DF381.863e-8240.31Innexin OS=Macrostomum lignano OX=282301 GN=inx PE... [more]
A0A1I8J2L71.863e-8240.31Innexin OS=Macrostomum lignano OX=282301 GN=inx PE... [more]
A0A0N4UAF64.492e-7939.59Innexin OS=Dracunculus medinensis OX=318479 GN=inx... [more]
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BLAST of Innexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000055733.10.000e+0100.00SMESG000055733.1[more]
SMESG000056430.15.311e-6935.94SMESG000056430.1[more]
SMESG000065921.13.632e-6436.49SMESG000065921.1[more]
SMESG000056430.11.015e-6335.66SMESG000056430.1[more]
SMESG000035987.11.017e-6339.13SMESG000035987.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010974 ID=SMED30010974|Name=Innexin|organism=Schmidtea mediterranea sexual|type=transcript|length=2663bp
ATTGAATTAAAATTGAACTCATAACAGCTGATAACATGATAAAAAACATC
TATTTCCTGTTTCTCAAATTTCTAGTGAAAACCGCTGTTCAGTTGTTTCT
GTTAACAGCTACCAGAAACCCTCATTGGAGTGGAGTGTTTTAAGAAATAT
ATAATGATACATAAATTACCGGATACTATTGTGAAAAATTCCTGTTTTGA
AATTTTTGAAGGTTTTCTGAATCTTGTTGATGTTAGAGTTTTTGTTATGA
CATTACTCCTTTTTACTCTACTGTAACAATTTTGAAATGGTATTCGGCTG
TCAGTCAATCATGATGACCTCCAATGAAACTTACCGTGGTATTTAGAAAT
GGGATTTTACTTTATGAGTTAGAAGGTTAGAGAGTGGATTGTAAATTGAT
AATTTTGTAGTTTTCTTATGATAATATAAAATTACATCAAATCGTAGAGA
CTAAGAAGACATGGCCGATGTGCATTTTCCAAAGAAATAATTCACAATCT
CACGCACAATATTTTATCGAAGCCACTAATTTGGTTCTAATGACTAGGGA
TTGAACGGTTCGTGTTGAGAGCCGTTTTGACCGAAAGAAGCATTGTGAAA
TGTCTAGAATGTTATATTTTCTTTTCAAAGACAAAATAGTTTTGGAAAAG
ATGGTTTTTTGCTTGAGTTTTTTATACCATATTTTAGGGTATCACGACAC
GTCGTGTACTGACATCTGGTTTATTGAAACTTAGTCGATGGTAAGTACAC
CAGCAAAATTCCCCAACAAAATTCCTTCATTATTTAAATTTTGTTATTAA
CCAGGCTCCCTTTACCGCCCGTCAAAACTGCCGCTCATTCAAAGCAGTGA
ACATCAAAACCGGAGCTATAATAATAGTGCCGATTGTACCCGCGCGTCGT
AGTGATGTATTAATTGTAATAACTGGTTAAGTCGATTAAGGCGGAATTCA
AAGCCTCAAGCGATTCCATATAACTAAAACTTACGTTAATTTATGTTTTT
AAAAGTTTTTTTTCCATTGCCTATTTATTTCAGGTAAAGCAAATTCGTAA
ATTCATTAAAATTTATCGATTTGTTTTAATTGATAAAATGAGATGCCTTT
TGAACTCAATATGTTTTTCATTTCGGTTCAAAGGTCAACAGCTGATCGGG
TTGTAAGTGATTTTCAGTTGATAATAAACTCATTAAAAATAGAACATGGA
TAAAGGTTTGTTGACGAAACTTCAGGGAATCAAGCTAACAAGTCATTTGA
AAAGAATAAGCGATGAAGATTTCGTCGACAGAATAAACAATTTCTACACT
CCTTTGCTACTGACAATTTTTTCAATCGTCATCTGCACAAAGTCTTACAT
TGTTGGTGAGCCATTGCAGTGCTGGGTACCAGTTCATTTTAGTGACGGTT
GGGAGAAATATTCAGAGTCTTGGTGTTATATAAAAAATACTTATTACGTT
CCAAGGGAGAAAGAAATACCAACAGAAAAAACAATGAGAGAAAACTCAGA
ATTACAGTATTACCAATGGGTTCCCTTCGTTTTAGGATTACAGGCTGTTC
TATTTTTGTTACCATCAATCTTATGGAAATTCTTAAATTGGCAAGGAAGA
ATTCATATTAAACCATTAGTCAAAAGAGCTGTTTTGTCATCATATGAGAA
ATACGAAGACCGAGTTAAGACTTTGCATAAGATTTCAGAACACATTCAAA
ATAGTCTTTTTAAACAAAGATTTAAAAATCATATCACAATCAGCCAGAGA
AATTCTAAAGGCTGCGGACTTTTGAATTCAGGATTTTATTTGACCTTTTG
TTACATTGGGTGTAAGATATTATACGTGCTCAACATTATTATGCAGTTCA
TTATCGTCCATACGTTTTTGAAAGCTAATTTCCTTTTTGGTTTCAAGCTC
TTGTCCACCTTGGCTAGCGGATCGGATTGGCAACAAACCGGACTTTTTCC
CAGAGTGACATTGTGCGATTTCACAATTCCTAGAGTAGGTCAGGAACTCC
ACACCTCAATGCAATGCGTTTTAGTTATCAATCTGTTTAATGAGAAAATT
TACATTTTTATTTGGTTTTGGTTGGCGTTTTTATTCTTTATTACTGTTGG
CAATTTATTTGTGTGGATTGCTCGGATGGTCCTTGGCAAAAAGTTGACGG
TTTTCCTTTCAAAGAAATCAGATTACATGTCGAATGAATTTTCTGCGTTG
CACGCATGCAATTCGGAGACCTGCTCTGATGTTTATTTGATTCTAAGACT
TTTGGAGACTAACTGTGGAATATTGACTACTCGTAAAATAACAGAAAATT
TGCTTGAATACTACAAGCAGCCGGAGCACCTAGGGAAATACAATTCCTTG
CCACCGAACTACCATGAGTTAGACAAGAATGATAACCATTCAATAATGTC
CTCGGAGTCATCCTAATCTGGCCTTCACATTGCTTATATTTATATATCTG
ATTGCCTATCATTAAAACATCCAAATATTTCATTCCCCAATTTCTTTTTC
TACGTGATGTGCTCCTAACCGTTTATTACCGAAATTTTAGTGTTTGATCA
ATAATACATTTCTAAATTAATACTTTCATTCTTCAACTATTTAATGCTAA
CAACTTATTTGTTTTAATAAATGCCAATGAATAATTTTTAATTAATATAT
TTTTAAATACAAT
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protein sequence of SMED30010974-orf-1

>SMED30010974-orf-1 ID=SMED30010974-orf-1|Name=SMED30010974-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=407bp
MDKGLLTKLQGIKLTSHLKRISDEDFVDRINNFYTPLLLTIFSIVICTKS
YIVGEPLQCWVPVHFSDGWEKYSESWCYIKNTYYVPREKEIPTEKTMREN
SELQYYQWVPFVLGLQAVLFLLPSILWKFLNWQGRIHIKPLVKRAVLSSY
EKYEDRVKTLHKISEHIQNSLFKQRFKNHITISQRNSKGCGLLNSGFYLT
FCYIGCKILYVLNIIMQFIIVHTFLKANFLFGFKLLSTLASGSDWQQTGL
FPRVTLCDFTIPRVGQELHTSMQCVLVINLFNEKIYIFIWFWLAFLFFIT
VGNLFVWIARMVLGKKLTVFLSKKSDYMSNEFSALHACNSETCSDVYLIL
RLLETNCGILTTRKITENLLEYYKQPEHLGKYNSLPPNYHELDKNDNHSI
MSSESS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
Vocabulary: INTERPRO
TermDefinition
IPR000990Innexin
Vocabulary: cellular component
TermDefinition
GO:0005921gap junction
GO:0005886plasma membrane
GO:0016020membrane
GO:0016021integral component of membrane
GO:0030054cell junction
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0006811ion transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000990InnexinPRINTSPR01262INNEXINcoord: 48..59
score: 35.33
coord: 76..85
score: 44.0
coord: 203..217
score: 42.4
coord: 105..127
score: 60.7
coord: 274..290
score: 64.0
coord: 250..259
score: 74.4
IPR000990InnexinPFAMPF00876Innexincoord: 24..373
e-value: 4.9E-93
score: 312.2
IPR000990InnexinPANTHERPTHR11893INNEXINcoord: 13..378
IPR000990InnexinPROSITEPS51013PANNEXINcoord: 19..379
score: 31.178
NoneNo IPR availableTMHMMTMhelixcoord: 30..52
NoneNo IPR availableTMHMMTMhelixcoord: 199..221
NoneNo IPR availableTMHMMTMhelixcoord: 286..308
NoneNo IPR availableTMHMMTMhelixcoord: 105..127