mitochondrial calcium uniporter regulator 1
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30010958 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Human
Match: MCUR1 (mitochondrial calcium uniporter regulator 1 [Source:HGNC Symbol;Acc:HGNC:21097]) HSP 1 Score: 78.9518 bits (193), Expect = 2.328e-16 Identity = 54/195 (27.69%), Postives = 108/195 (55.38%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIM-EDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFN-------QIKSEIV-----------KTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 L DTH +V + +GF+ QQAE + + +L +I+ +DM + + Q F+ Q++++++N+KKD+I F+ ++ ENEK K+E+ L+QQ+ DE+ K N E+SR ++ ++ ++++EIV +T +I++++A L+T E ++ + +KY G++ + +A+ F Sbjct: 164 LYFDTHALVCLLEDNGFATQQAEIIVSALVKILEANMDIVYKDMVTKMQQEITFQ----QVMSQIANVKKDMIILEKSEFSALRAENEKIKLELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDRALTQTDRKIETEVAGLKTMLESHKLDNIKYLAGSIFTCLTVALGF 354
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Human
Match: CCDC90B (coiled-coil domain containing 90B [Source:HGNC Symbol;Acc:HGNC:28108]) HSP 1 Score: 75.8702 bits (185), Expect = 8.348e-16 Identity = 57/194 (29.38%), Postives = 94/194 (48.45%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDF------------------NQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 L DTH +VQ+ +T GF + QAE + L N ++ + + + + E+ QL+ + I+KD++ F ++ ENEK K+E+ ++QQL E + IN E+SR D F Q KS I +T N+ID++IA+L+T E + E ++Y +V + IA+ F Sbjct: 50 LTFDTHALVQDLETHGFDKTQAETIVSALTALSNVS---LDTIYKEMVTQAQQEITVQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIASLKTLMESNKLETIRYLAASVFTCLAIALGF 240
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Human
Match: CCDC90B (coiled-coil domain containing 90B [Source:HGNC Symbol;Acc:HGNC:28108]) HSP 1 Score: 75.485 bits (184), Expect = 1.209e-15 Identity = 57/194 (29.38%), Postives = 94/194 (48.45%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDF------------------NQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 L DTH +VQ+ +T GF + QAE + L N ++ + + + + E+ QL+ + I+KD++ F ++ ENEK K+E+ ++QQL E + IN E+SR D F Q KS I +T N+ID++IA+L+T E + E ++Y +V + IA+ F Sbjct: 59 LTFDTHALVQDLETHGFDKTQAETIVSALTALSNVS---LDTIYKEMVTQAQQEITVQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIASLKTLMESNKLETIRYLAASVFTCLAIALGF 249
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Human
Match: CCDC90B (coiled-coil domain containing 90B [Source:HGNC Symbol;Acc:HGNC:28108]) HSP 1 Score: 58.5362 bits (140), Expect = 3.410e-10 Identity = 43/141 (30.50%), Postives = 69/141 (48.94%), Query Frame = 1 Query: 340 ELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDF------------------NQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 E+ QL+ + I+KD++ F ++ ENEK K+E+ ++QQL E + IN E+SR D F Q KS I +T N+ID++IA+L+T E + E ++Y +V + IA+ F Sbjct: 8 EITVQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIASLKTLMESNKLETIRYLAASVFTCLAIALGF 148
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Human
Match: CCDC90B (coiled-coil domain containing 90B [Source:HGNC Symbol;Acc:HGNC:28108]) HSP 1 Score: 58.5362 bits (140), Expect = 3.410e-10 Identity = 43/141 (30.50%), Postives = 69/141 (48.94%), Query Frame = 1 Query: 340 ELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDF------------------NQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 E+ QL+ + I+KD++ F ++ ENEK K+E+ ++QQL E + IN E+SR D F Q KS I +T N+ID++IA+L+T E + E ++Y +V + IA+ F Sbjct: 8 EITVQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIASLKTLMESNKLETIRYLAASVFTCLAIALGF 148
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Zebrafish
Match: MCUR1 (zgc:165532 [Source:ZFIN;Acc:ZDB-GENE-050417-213]) HSP 1 Score: 82.8037 bits (203), Expect = 2.138e-18 Identity = 60/185 (32.43%), Postives = 101/185 (54.59%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIM-EDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRD---DFN-----------QIKSE----IVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV 678 L DTH +VQ + SGF QQAE + +N+ N+ +IM DM + +QE L ++++ ++ +KKD+I F+ + ENEK K+E+ LR QL D I+K + +N E+SR ++ DFN ++ SE + +T +ID+++A L+T E ++ + +KY G+V Sbjct: 63 LFFDTHAMVQLLEESGFMTQQAEVIVKMMVNITNSNMDIMYSDMATK--TQQEIMLQ--KVMSHIAAVKKDMIILEKSEFSALLAENEKIKVELLQLRIQLADVINKRRADIILDLNIEKSRVKEMWADFNRKLIGTRNELLEMNSEQDRHVTQTNMKIDTEVAGLKTMLEAHKLDTIKYLAGSV 243
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Zebrafish
Match: ccdc90b (coiled-coil domain containing 90B [Source:ZFIN;Acc:ZDB-GENE-040724-162]) HSP 1 Score: 78.9518 bits (193), Expect = 5.088e-17 Identity = 67/242 (27.69%), Postives = 117/242 (48.35%), Query Frame = 1 Query: 43 KNNLYLNPFF-CIFLMIFYKTFKYIQLFNFNKFCTKVKHDVLSKRLMLVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIM-EDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQ------------------IKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 +N LY + CIFL+ +KT ++ ++ K V+ L +R L D+H +V+E ++SGF ++QAE + + L +I+ DM + Q E+ Q++ + I+KD++ F ++ EN K K E++ + +L +E K IN E+SR D F + I+SE V+T +ID Q+A+L+T E + E ++Y + + IA+ F Sbjct: 14 QNGLYWSQHGRCIFLLGLHKT-TAVKTYDVRK----VELTPLEQR-KLTFDSHALVKELESSGFEKRQAELIVTALVTLTTANIDIVYRDMVTGAHQ----EIALQQIMAHLDAIRKDMVILEKSEFANLRSENAKMKTELEQITNRLLEESQKIRAEAKLDINLERSRVTDMFTEQEKKLMDVRMEFQKMNADIESEAVETSKKIDIQVASLKTLLESLKLETVRYLAACIFTCLAIALGF 245
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Zebrafish
Match: ccdc90b (coiled-coil domain containing 90B [Source:ZFIN;Acc:ZDB-GENE-040724-162]) HSP 1 Score: 77.411 bits (189), Expect = 1.649e-16 Identity = 64/231 (27.71%), Postives = 112/231 (48.48%), Query Frame = 1 Query: 73 CIFLMIFYKTFKYIQLFNFNKFCTKVKHDVLSKRLMLVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIM-EDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQ------------------IKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 CIFL+ +KT ++ ++ K V+ L +R L D+H +V+E ++SGF ++QAE + + L +I+ DM + Q E+ Q++ + I+KD++ F ++ EN K K E++ + +L +E K IN E+SR D F + I+SE V+T +ID Q+A+L+T E + E ++Y + + IA+ F Sbjct: 33 CIFLLGLHKT-TAVKTYDVRK----VELTPLEQR-KLTFDSHALVKELESSGFEKRQAELIVTALVTLTTANIDIVYRDMVTGAHQ----EIALQQIMAHLDAIRKDMVILEKSEFANLRSENAKMKTELEQITNRLLEESQKIRAEAKLDINLERSRVTDMFTEQEKKLMDVRMEFQKMNADIESEAVETSKKIDIQVASLKTLLESLKLETVRYLAACIFTCLAIALGF 253
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Zebrafish
Match: ccdc90b (coiled-coil domain containing 90B [Source:ZFIN;Acc:ZDB-GENE-040724-162]) HSP 1 Score: 71.633 bits (174), Expect = 2.171e-14 Identity = 54/195 (27.69%), Postives = 94/195 (48.21%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIM-EDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQ------------------IKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 L D+H +V+E ++SGF ++QAE + + L +I+ DM + Q E+ Q++ + I+KD++ F ++ EN K K E++ + +L +E K IN E+SR D F + I+SE V+T +ID Q+A+L+T E + E ++Y + + IA+ F Sbjct: 58 LTFDSHALVKELESSGFEKRQAELIVTALVTLTTANIDIVYRDMVTGAHQ----EIALQQIMAHLDAIRKDMVILEKSEFANLRSENAKMKTELEQITNRLLEESQKIRAEAKLDINLERSRVTDMFTEQEKKLMDVRMEFQKMNADIESEAVETSKKIDIQVASLKTLLESLKLETVRYLAACIFTCLAIALGF 248
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Zebrafish
Match: MCUR1 (zgc:165532 [Source:ZFIN;Acc:ZDB-GENE-050417-213]) HSP 1 Score: 50.8322 bits (120), Expect = 8.917e-8 Identity = 34/106 (32.08%), Postives = 58/106 (54.72%), Query Frame = 1 Query: 415 FNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRD---DFN-----------QIKSE----IVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV 678 F+ + ENEK K+E+ LR QL D I+K + +N E+SR ++ DFN ++ SE + +T +ID+++A L+T E ++ + +KY G+V Sbjct: 9 FSALLAENEKIKVELLQLRIQLADVINKRRADIILDLNIEKSRVKEMWADFNRKLIGTRNELLEMNSEQDRHVTQTNMKIDTEVAGLKTMLEAHKLDTIKYLAGSV 114
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Xenopus
Match: mcur1 (mitochondrial calcium uniporter regulator 1 [Source:NCBI gene;Acc:780306]) HSP 1 Score: 74.7146 bits (182), Expect = 1.635e-15 Identity = 51/191 (26.70%), Postives = 104/191 (54.45%), Query Frame = 1 Query: 190 DTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRD-------DFNQIKSEIV-----------KTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 DTH VVQ + +GFS +Q+E + + +LN M ++ + +++ E+ Q+++ ++++KKD+I F+ ++ +NEK K+E+Q L++QL D I K N E+SR ++ ++++ IV +T+ +ID++++ ++T E ++ + +KY G+V + IA+ F Sbjct: 35 DTHAVVQLLEANGFSAEQSEIVVSALVKILNVN---MNLIHKDMVTKEQQEISLQQVMSLIASVKKDMIILEKSEFSALRTQNEKVKIELQQLKKQLNDSIVKVRASNKLDFNLEKSRVKEMHADNERKLLELRTSIVELHSQQDRGLTQTKRKIDTEVSGVKTMQESHKLDTIKYLAGSVFTCLTIALGF 222
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Xenopus
Match: mcur1 (mitochondrial calcium uniporter regulator 1 [Source:NCBI gene;Acc:780306]) HSP 1 Score: 75.0998 bits (183), Expect = 2.180e-15 Identity = 54/192 (28.12%), Postives = 106/192 (55.21%), Query Frame = 1 Query: 190 DTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIM-EDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRD-------DFNQIKSEIV-----------KTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 DTH VVQ + +GFS +Q+E + + +LN ++ +DM + ++QE L Q+++ ++++KKD+I F+ ++ +NEK K+E+Q L++QL D I K N E+SR ++ ++++ IV +T+ +ID++++ ++T E ++ + +KY G+V + IA+ F Sbjct: 70 DTHAVVQLLEANGFSAEQSEIVVSALVKILNVNMNLIHKDMVTK--EQQEISLQ--QVMSLIASVKKDMIILEKSEFSALRTQNEKVKIELQQLKKQLNDSIVKVRASNKLDFNLEKSRVKEMHADNERKLLELRTSIVELHSQQDRGLTQTKRKIDTEVSGVKTMQESHKLDTIKYLAGSVFTCLTIALGF 257
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Xenopus
Match: ccdc90b (coiled-coil domain containing 90B [Source:NCBI gene;Acc:448234]) HSP 1 Score: 69.707 bits (169), Expect = 1.493e-13 Identity = 53/195 (27.18%), Postives = 94/195 (48.21%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAE-IMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQ------------------IKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 L DTH +V+E +T GF + QAE + L N + + DM R + E+ Q++ + +I+KD++ F ++ ENEK K+E++ +RQ L +E ++ + +N E+SR D F + S I + +ID IA+L+T E ++ + ++Y +V + IA+ F Sbjct: 53 LTFDTHALVRELETHGFDKVQAETIVSALATLTNASIDTVYRDM----VTRAQQEITVQQIMAHLDSIRKDMVILEKSEFATLRAENEKMKIELEHVRQHLLNETNRISADAKLDMNLERSRLTDLFTEQEKKLMEASTEFHKKNATTDSVITEINKKIDIDIASLKTLMESHKLDTVRYMAASVFTCLAIALGF 243
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Xenopus
Match: ccdc90b (coiled-coil domain containing 90B [Source:NCBI gene;Acc:448234]) HSP 1 Score: 68.9366 bits (167), Expect = 3.817e-13 Identity = 53/195 (27.18%), Postives = 94/195 (48.21%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAE-IMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQ------------------IKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 L DTH +V+E +T GF + QAE + L N + + DM R + E+ Q++ + +I+KD++ F ++ ENEK K+E++ +RQ L +E ++ + +N E+SR D F + S I + +ID IA+L+T E ++ + ++Y +V + IA+ F Sbjct: 92 LTFDTHALVRELETHGFDKVQAETIVSALATLTNASIDTVYRDM----VTRAQQEITVQQIMAHLDSIRKDMVILEKSEFATLRAENEKMKIELEHVRQHLLNETNRISADAKLDMNLERSRLTDLFTEQEKKLMEASTEFHKKNATTDSVITEINKKIDIDIASLKTLMESHKLDTVRYMAASVFTCLAIALGF 282
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Xenopus
Match: mcur1 (mitochondrial calcium uniporter regulator 1 [Source:NCBI gene;Acc:780306]) HSP 1 Score: 67.3958 bits (163), Expect = 7.656e-13 Identity = 50/176 (28.41%), Postives = 98/176 (55.68%), Query Frame = 1 Query: 190 DTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIM-EDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQL--KDEIDKTNNGMTSTINFEQSRTRDDFNQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 DTH VVQ + +GFS +Q+E + + +LN ++ +DM + ++QE L Q+++ ++++KKD+I F+ ++ +NEK K+E+Q L++QL D K TS + + R + +T+ +ID++++ ++T E ++ + +KY G+V + IA+ F Sbjct: 70 DTHAVVQLLEANGFSAEQSEIVVSALVKILNVNMNLIHKDMVTK--EQQEISLQ--QVMSLIASVKKDMIILEKSEFSALRTQNEKVKIELQQLKKQLNHADNERKLLELRTSIVELHSQQDRG--------LTQTKRKIDTEVSGVKTMQESHKLDTIKYLAGSVFTCLTIALGF 233
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Mouse
Match: Mcur1 (mitochondrial calcium uniporter regulator 1 [Source:MGI Symbol;Acc:MGI:1923387]) HSP 1 Score: 83.9593 bits (206), Expect = 2.714e-18 Identity = 61/219 (27.85%), Postives = 117/219 (53.42%), Query Frame = 1 Query: 121 FNFNKFCTKVKHD----VLSKRLMLVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIM-EDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFN-------QIKSEIV-----------KTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 + + C +++H LS L DTH +V + +GF+ QQAE + + + T I+ +DM S + +QE L Q+L++++N+KKD++ F+ ++ ENEK K+E+ L+QQ+ DE+ K N E+SR ++ ++ ++++EIV +T +I++++A L+T E ++ + +KY G+V + +A+ F Sbjct: 121 LSLSAKCHQLEHRKENLPLSVSRQLYFDTHALVCLLEANGFTIQQAEIIVSALVKITETNMNIIYKDMVSKM--QQEIALQ--QVLSKIANVKKDMVILEKSEFSALRAENEKIKLELHQLKQQVMDEVTKVRTDTKLNFNLEKSRVKELYSLNEKKMLELRTEIVSLHAQQDRALTQTDRKIETEVAGLKTMLEAHKLDTIKYLAGSVFTCLTVALGF 335
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Mouse
Match: Ccdc90b (coiled-coil domain containing 90B [Source:MGI Symbol;Acc:MGI:1913615]) HSP 1 Score: 78.1814 bits (191), Expect = 9.453e-17 Identity = 56/195 (28.72%), Postives = 102/195 (52.31%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEI-MEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDF------------------NQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 L DTH +VQ+ +T GF + QA+ + +++L+T + + ++ + + + + E+ QL+ + +I+KD++ F ++ ENEK K+E+ ++QQL +E + IN E+SR D F Q KS I +T N+ID++IA+L+T E + E ++Y +V + IA+ F Sbjct: 59 LTFDTHALVQDLETHGFDKTQAQTI----VSVLSTLSNVSLDTIYKEMVTKAQQEITVQQLMAHLDSIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLTNETSRIRADNKLDINLERSRVTDMFTDQEKQLIEATNEFAKKDTQTKSIISETSNKIDTEIASLKTLMESSKLETIRYLAASVFTCLAIALGF 249
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Mouse
Match: Ccdc90b (coiled-coil domain containing 90B [Source:MGI Symbol;Acc:MGI:1913615]) HSP 1 Score: 54.299 bits (129), Expect = 2.154e-8 Identity = 54/179 (30.17%), Postives = 86/179 (48.04%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAE-IMEDMNSHLFQRQEFELH--NDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 L DTH +VQ+ +T GF + QA+ + L N + I ++M + Q+ + EL QL E S I+ D NK+ E+S++ + Q K I+ TN F + T Q KS I +T N+ID++IA+L+T E + E ++Y +V + IA+ F Sbjct: 59 LTFDTHALVQDLETHGFDKTQAQTIVSVLSTLSNVSLDTIYKEMVTKAQQKMKIELDQVKQQLTNETSRIRAD---------NKLDINLERSRV-TDMFTDQEKQLIEATN-------EFAKKDT-----QTKSIISETSNKIDTEIASLKTLMESSKLETIRYLAASVFTCLAIALGF 215
BLAST of mitochondrial calcium uniporter regulator 1 vs. UniProt/SwissProt
Match: sp|Q9CXD6|MCUR1_MOUSE (Mitochondrial calcium uniporter regulator 1 OS=Mus musculus OX=10090 GN=Mcur1 PE=1 SV=1) HSP 1 Score: 83.9593 bits (206), Expect = 1.899e-17 Identity = 61/219 (27.85%), Postives = 117/219 (53.42%), Query Frame = 1 Query: 121 FNFNKFCTKVKHD----VLSKRLMLVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIM-EDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFN-------QIKSEIV-----------KTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 + + C +++H LS L DTH +V + +GF+ QQAE + + + T I+ +DM S + +QE L Q+L++++N+KKD++ F+ ++ ENEK K+E+ L+QQ+ DE+ K N E+SR ++ ++ ++++EIV +T +I++++A L+T E ++ + +KY G+V + +A+ F Sbjct: 121 LSLSAKCHQLEHRKENLPLSVSRQLYFDTHALVCLLEANGFTIQQAEIIVSALVKITETNMNIIYKDMVSKM--QQEIALQ--QVLSKIANVKKDMVILEKSEFSALRAENEKIKLELHQLKQQVMDEVTKVRTDTKLNFNLEKSRVKELYSLNEKKMLELRTEIVSLHAQQDRALTQTDRKIETEVAGLKTMLEAHKLDTIKYLAGSVFTCLTVALGF 335
BLAST of mitochondrial calcium uniporter regulator 1 vs. UniProt/SwissProt
Match: sp|Q8C3X2|CC90B_MOUSE (Coiled-coil domain-containing protein 90B, mitochondrial OS=Mus musculus OX=10090 GN=Ccdc90b PE=1 SV=1) HSP 1 Score: 78.1814 bits (191), Expect = 6.612e-16 Identity = 56/195 (28.72%), Postives = 102/195 (52.31%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEI-MEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDF------------------NQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 L DTH +VQ+ +T GF + QA+ + +++L+T + + ++ + + + + E+ QL+ + +I+KD++ F ++ ENEK K+E+ ++QQL +E + IN E+SR D F Q KS I +T N+ID++IA+L+T E + E ++Y +V + IA+ F Sbjct: 59 LTFDTHALVQDLETHGFDKTQAQTI----VSVLSTLSNVSLDTIYKEMVTKAQQEITVQQLMAHLDSIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLTNETSRIRADNKLDINLERSRVTDMFTDQEKQLIEATNEFAKKDTQTKSIISETSNKIDTEIASLKTLMESSKLETIRYLAASVFTCLAIALGF 249
BLAST of mitochondrial calcium uniporter regulator 1 vs. UniProt/SwissProt
Match: sp|Q96AQ8|MCUR1_HUMAN (Mitochondrial calcium uniporter regulator 1 OS=Homo sapiens OX=9606 GN=MCUR1 PE=1 SV=1) HSP 1 Score: 78.9518 bits (193), Expect = 1.118e-15 Identity = 54/195 (27.69%), Postives = 108/195 (55.38%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIM-EDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFN-------QIKSEIV-----------KTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 L DTH +V + +GF+ QQAE + + +L +I+ +DM + + Q F+ Q++++++N+KKD+I F+ ++ ENEK K+E+ L+QQ+ DE+ K N E+SR ++ ++ ++++EIV +T +I++++A L+T E ++ + +KY G++ + +A+ F Sbjct: 164 LYFDTHALVCLLEDNGFATQQAEIIVSALVKILEANMDIVYKDMVTKMQQEITFQ----QVMSQIANVKKDMIILEKSEFSALRAENEKIKLELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDRALTQTDRKIETEVAGLKTMLESHKLDNIKYLAGSIFTCLTVALGF 354
BLAST of mitochondrial calcium uniporter regulator 1 vs. UniProt/SwissProt
Match: sp|Q4V897|CC90B_RAT (Coiled-coil domain-containing protein 90B, mitochondrial OS=Rattus norvegicus OX=10116 GN=Ccdc90b PE=2 SV=1) HSP 1 Score: 77.411 bits (189), Expect = 1.555e-15 Identity = 56/195 (28.72%), Postives = 102/195 (52.31%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEI-MEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFN------------------QIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 L DTH +VQ+ +T GF + QA+ + +++L+T + + ++ + + + + E+ QL+ + +I+KD++ F ++ ENEK K+E+ ++QQL +E + IN E+SR D F Q KS I +T N+ID++IA+L+T E + E ++Y +V + IA+ F Sbjct: 59 LTFDTHALVQDLETHGFDKGQAQTI----VSVLSTLSNVSLDTVYKEMVTKAQQEITIQQLMAHLDSIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLINETSRIRADNRLDINLERSRVTDMFTDQEKQLMEATNEFTKKDMQTKSIISETSNKIDTEIASLKTLMESSKLETIRYLAASVFTCLAIALGF 249
BLAST of mitochondrial calcium uniporter regulator 1 vs. UniProt/SwissProt
Match: sp|Q9GZT6|CC90B_HUMAN (Coiled-coil domain-containing protein 90B, mitochondrial OS=Homo sapiens OX=9606 GN=CCDC90B PE=1 SV=2) HSP 1 Score: 75.485 bits (184), Expect = 5.806e-15 Identity = 57/194 (29.38%), Postives = 94/194 (48.45%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDF------------------NQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 L DTH +VQ+ +T GF + QAE + L N ++ + + + + E+ QL+ + I+KD++ F ++ ENEK K+E+ ++QQL E + IN E+SR D F Q KS I +T N+ID++IA+L+T E + E ++Y +V + IA+ F Sbjct: 59 LTFDTHALVQDLETHGFDKTQAETIVSALTALSNVS---LDTIYKEMVTQAQQEITVQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIASLKTLMESNKLETIRYLAASVFTCLAIALGF 249
BLAST of mitochondrial calcium uniporter regulator 1 vs. TrEMBL
Match: A0A1S3JPQ3 (mitochondrial calcium uniporter regulator 1 OS=Lingula unguis OX=7574 GN=LOC106175068 PE=4 SV=1) HSP 1 Score: 105.916 bits (263), Expect = 1.395e-23 Identity = 53/171 (30.99%), Postives = 101/171 (59.06%), Query Frame = 1 Query: 190 DTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAVIVIAVSFV 702 DTH +++ ++SGF+ QQAE L + +LN Q ++ + + + E+ Q++ E+S++KKD++ F+ +K+ENEK +E+ L+ + D K +G+ IN E+SR+++ + + + +NRID+++ANL+T E+YR++ KY +G + + V V Sbjct: 86 DTHALIKHLESSGFTSQQAEGLSSAFIQILNAQ---IDQQTKTMVYKGQLEITTQQIMAEISSVKKDMVILEKSEFSTLKNENEKKTLELNRLKDNMSDGFAKLQSGVKLDINLERSRSQEAHATNEKTLSRLENRIDTEVANLKTLIELYRSDYYKYVLGLCMTLIVGVV 253
BLAST of mitochondrial calcium uniporter regulator 1 vs. TrEMBL
Match: T1ED25 (Uncharacterized protein OS=Helobdella robusta OX=6412 GN=20194477 PE=4 SV=1) HSP 1 Score: 104.375 bits (259), Expect = 3.187e-23 Identity = 71/233 (30.47%), Postives = 126/233 (54.08%), Query Frame = 1 Query: 91 FYKTFKYIQLFNFNKFCTKV---------KHDVLSKRLMLVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQIKSEIVKTQNR------------------IDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 F K++ +I++FN +K C K+ K D+ + + + DTH +++ + SG + QAE L A +L+ M+ +N +L +++ E+ Q+L+ +S+IKKD+I F+ +K E EK +EI+ +++ KDEI+ +G+ +N E+SR +D + + + K +NR I+ +IANL ++E YRN+V+KYA GAV + I + F Sbjct: 19 FPKSY-FIEVFNHSK-CNKIQVRKCLESRKVDLTGAKQVYMFDTHLLIKSLQDSGIAPNQAETL---AYSLVQITQGHMDFVNKNLITKEQQEILLQQILSHISSIKKDMIILEKSEFSNLKHEYEKQNIEIEQMKRHFKDEINNLKSGVALDMNLEKSRAKDAHAESEKALTKLENRIGIMSSEHDKHISGMDNKIEKEIANLLATYERYRNDVIKYAAGAVMTCLTICLGF 246
BLAST of mitochondrial calcium uniporter regulator 1 vs. TrEMBL
Match: A0A0L8G681 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22000041mg PE=4 SV=1) HSP 1 Score: 103.219 bits (256), Expect = 7.662e-23 Identity = 58/179 (32.40%), Postives = 105/179 (58.66%), Query Frame = 1 Query: 172 RLMLVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 R L DTH +VQ+ + GF+ +QAEA+ + ++N +E + + + + E+ QLL E++ +KKD+I F+ +++ EK +I L+ ++DE+ K + +N E+ RT ++F +++I N+ID++IA+LRT+FE +RN+VLKYA G + + I++ F Sbjct: 51 RKTLHCDTHALVQQLQLRGFTIEQAEAITEALVEVVNM---TLEQQSKEMVTKTQQEIVTQQLLAEIAAVKKDMIILEKSEFSNLRNITEKQSRDILQLKDTVRDEVSKLEGKILLDVNLERGRTNEEFADKETQISNINNKIDTKIADLRTTFEQHRNDVLKYAGGTIFSCLTISLGF 226
BLAST of mitochondrial calcium uniporter regulator 1 vs. TrEMBL
Match: A0A3S1A344 (Uncharacterized protein OS=Elysia chlorotica OX=188477 GN=EGW08_002848 PE=4 SV=1) HSP 1 Score: 93.9745 bits (232), Expect = 3.386e-19 Identity = 54/172 (31.40%), Postives = 95/172 (55.23%), Query Frame = 1 Query: 190 DTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAVIVIAVSFVA 705 DT ++ + +GFS QQAEA + ++NT ++ H+ + + E+ QLL+E+ ++KKD+ F+ +K E EK ++ + + + DEI K + IN E+ R + + + + + N+ID++IANL+T +EMYRN+V KYA G V+ + +A Sbjct: 90 DTLAFSKKLEGNGFSRQQAEACAECLVEIINT---TLDHQGRHMVTKPQQEIAVQQLLSEIVSVKKDMTLLQKSEFSSLKTETEKIRIALNQSQDHMNDEIVKLKGQFSLDINLERGRAIEAHAENEKRLQQLHNKIDTEIANLKTVYEMYRNDVFKYAGGTVLAVGSIVLA 258
BLAST of mitochondrial calcium uniporter regulator 1 vs. TrEMBL
Match: R7U2J8 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_168302 PE=4 SV=1) HSP 1 Score: 91.6633 bits (226), Expect = 8.128e-19 Identity = 59/191 (30.89%), Postives = 106/191 (55.50%), Query Frame = 1 Query: 190 DTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRT----RDDFNQI----------KSEIVKT----QNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 DTH +V++F+ GF+E+Q+E L + L E ++ ++ + + E+ Q+ T +S +KKD++ F++++ E EK +E++ LR+QL D+I K G+T +N E+SR+ +D +I KSE ++ N+I +++NL ++E YRN+V+KYA G V + I + F Sbjct: 6 DTHALVKKFQACGFTERQSEELVN---GLCEISQEGLDHTGRNMVTKPQQEIMVQQIHTHLSALKKDMVILEKSEFSQLRHEYEKQNIELRQLRKQLDDDIMKLKAGVTLDLNLEKSRSVESHQDSLREIQQLMNKLDIQKSETARSLAGLDNKISREVSNLIATYERYRNDVMKYAAGTVLSCLTICLGF 193
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Cavefish
Match: ccdc90b (coiled-coil domain containing 90B [Source:NCBI gene;Acc:103026619]) HSP 1 Score: 69.3218 bits (168), Expect = 1.263e-13 Identity = 51/195 (26.15%), Postives = 95/195 (48.72%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIM-EDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDF------------------NQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV---IVIAVSF 699 L D+H VV+E +++GF ++QAE + + L +I+ DM + Q E+ Q++ + +I+KD++ F ++ EN K K E++ ++ +L DE K IN E+SR D F +I+S V T +ID ++A+L+T E + + ++Y + +V+++ F Sbjct: 66 LTFDSHAVVKELESNGFEKKQAEVIVTALVTLTTANMDIVYRDMVTGAHQ----EIALQQIMAHLDSIRKDMVILEKSEFASLRSENAKMKTELEQIKNRLFDESQKIRADAKLDINLERSRVTDMFTEQEKKLMEVNSEFNKKTGEIESSTVDTTKKIDIEVASLKTLLESLKLQTVRYLAACIFSCLVLSLGF 256
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Cavefish
Match: zgc:165532 (mitochondrial calcium uniporter regulator 1-like [Source:NCBI gene;Acc:103039460]) HSP 1 Score: 69.3218 bits (168), Expect = 2.967e-13 Identity = 48/184 (26.09%), Postives = 98/184 (53.26%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQIKSEIVKTQN------------------RIDSQIANLRTSFEMYRNEVLKYAVGAV 678 L+ DTH + Q + SGF+ QQAE + +N NT +IM S + + + E+ ++++ ++ +KKD+I F+ + EN++ K+E+ L+ QL D ++K +N E+S+ ++ + + ++++T+N +ID+++A L+T E ++ + +KY G+V Sbjct: 151 LMFDTHAMFQYLEASGFTSQQAEIIIKILVNTTNTNMDIM---YSDMVTKTQHEIMLQKVMSHITAVKKDMIILEKSEFSALLAENDRIKVELAQLKIQLLDMMNKVRVDNKLDMNLEKSQVKEMKAEHEKKLLETRNEMIEMLAEQERHVTQNNVKIDTEVAGLKTMLESHKLDSIKYLAGSV 331
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Cavefish
Match: zgc:165532 (mitochondrial calcium uniporter regulator 1-like [Source:NCBI gene;Acc:103039460]) HSP 1 Score: 55.8398 bits (133), Expect = 8.107e-9 Identity = 47/178 (26.40%), Postives = 94/178 (52.81%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENE--------KSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQIKSEIVK--TQN--RIDSQIANLRTSFEMYRNEVLKYAVGAV 678 L+ DTH + Q + SGF+ QQAE + +N NT +I M S + + + E+ ++++ ++ +KKD+I F+ + EN+ +K+++ L + Q+K+ M + + TR++ ++ +E + TQN +ID+++A L+T E ++ + +KY G+V Sbjct: 151 LMFDTHAMFQYLEASGFTSQQAEIIIKILVNTTNTNMDI---MYSDMVTKTQHEIMLQKVMSHITAVKKDMIILEKSEFSALLAENDDMMNKVRVDNKLDMNLEKSQVKE--------MKAEHEKKLLETRNEMIEMLAEQERHVTQNNVKIDTEVAGLKTMLESHKLDSIKYLAGSV 317
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Sea Lamprey
Match: zgc:165532 (mitochondrial calcium uniporter regulator 1 [Source:HGNC Symbol;Acc:HGNC:21097]) HSP 1 Score: 57.7658 bits (138), Expect = 1.279e-10 Identity = 36/137 (26.28%), Postives = 77/137 (56.20%), Query Frame = 1 Query: 190 DTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQIKSEIVKTQNRI 600 DTH +V +++GF+ QAE L + +LN ME + + + + E+ Q++ ++ +KKD+I F+ ++++NEK K+E+ L++ +DE K + +N E+SR ++ F++ + ++++ + I Sbjct: 54 DTHAMVLLLESNGFATGQAEVLVAALVKILNAN---MEAVYREMVTKSQQEIMLQQVMAHLAAVKKDMIILEKSEFSALRNDNEKMKIELIHLKKHFEDEFLKVKSDAKLDMNLEKSRVKEMFSEQEKKLLEMRTEI 187
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Nematostella
Match: EDO32032 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW75]) HSP 1 Score: 51.6026 bits (122), Expect = 6.714e-8 Identity = 44/172 (25.58%), Postives = 87/172 (50.58%), Query Frame = 1 Query: 190 DTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAVIVIAVSFVA 705 DTH ++ + + +GFS QQAE++ + ++NT + ++ E+ EV N ++ F ++K+ENEK K +++ L Q ++DE+ K + ++ E+SR ++ I N+I+++IA L T E + +++KY VG+++ +A Sbjct: 107 DTHKLILKLQENGFSTQQAESVTSCLVEIINTSISGLASNTLSTLDKERLEMKWKSTYDEVRN---EMFLLEKSKFAQVKEENEKLKEKVKALEQFMQDEMQKMKGSIRLDMSLEKSRRSEELAIRDQRIKDNGNKIETEIAKLGTQMETQKLDLIKYLVGSMVSCTTLMLA 275
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Medaka
Match: ccdc90b (coiled-coil domain containing 90B [Source:NCBI gene;Acc:101162701]) HSP 1 Score: 70.4774 bits (171), Expect = 3.355e-14 Identity = 52/195 (26.67%), Postives = 97/195 (49.74%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIM-EDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQIKSEIVKTQN------------------RIDSQIANLRTSFEMYRNEVLKYAVG---AVIVIAVSF 699 L D+H + E +TSGF +QQAE + + L +I+ +DM + Q E+ Q+++ + +I+KD++ F+ ++ EN K K E++ L +LK+E +K IN E+SR D F + + ++++ + +ID Q+A+L+T E + E ++Y A + I++ F Sbjct: 43 LTFDSHAMAAELETSGFDKQQAELIVSALVTLTTANMDIVYKDMVTKAHQ----EIAVQQIMSHLDSIRKDMVILEKSEFSNLRSENTKMKHELEQLHNRLKEETEKVRAETKLDINLERSRISDMFTEQEKKLMEATSEFHHKKADLENDNMEINKKIDLQVASLKTVLESLKLETIRYLAATLFACLAISLGF 233
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Medaka
Match: ccdc90b (coiled-coil domain containing 90B [Source:NCBI gene;Acc:101162701]) HSP 1 Score: 70.0922 bits (170), Expect = 6.143e-14 Identity = 52/195 (26.67%), Postives = 97/195 (49.74%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIM-EDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQIKSEIVKTQN------------------RIDSQIANLRTSFEMYRNEVLKYAVG---AVIVIAVSF 699 L D+H + E +TSGF +QQAE + + L +I+ +DM + Q E+ Q+++ + +I+KD++ F+ ++ EN K K E++ L +LK+E +K IN E+SR D F + + ++++ + +ID Q+A+L+T E + E ++Y A + I++ F Sbjct: 48 LTFDSHAMAAELETSGFDKQQAELIVSALVTLTTANMDIVYKDMVTKAHQ----EIAVQQIMSHLDSIRKDMVILEKSEFSNLRSENTKMKHELEQLHNRLKEETEKVRAETKLDINLERSRISDMFTEQEKKLMEATSEFHHKKADLENDNMEINKKIDLQVASLKTVLESLKLETIRYLAATLFACLAISLGF 238
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Medaka
Match: zgc:165532 (mitochondrial calcium uniporter regulator 1 [Source:NCBI gene;Acc:101166999]) HSP 1 Score: 62.3882 bits (150), Expect = 2.585e-11 Identity = 44/165 (26.67%), Postives = 85/165 (51.52%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIM-EDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVG 672 L DTH VV+ F+ +GFS QQAE + + + N+ +++ DM + + Q E+ +++++++ +KKD+I F+ + ENE D I K ++ +N E+SR ++ + +T +ID+++A L+T E ++ + +KY G Sbjct: 49 LFFDTHAVVRLFEENGFSTQQAEVMVNVLMRTTNSNMDVVYSDMVTKVHQ----EIMLQRVMSQIAAVKKDMIILEKSEFSALLAENE--------------DVIKKVHSDNMLDMNLEKSRVKELVTEQDRHFTETNMKIDTEVAGLKTMLESHKLDTIKYLAG 195
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Medaka
Match: zgc:165532 (mitochondrial calcium uniporter regulator 1 [Source:NCBI gene;Acc:101166999]) HSP 1 Score: 57.7658 bits (138), Expect = 9.599e-10 Identity = 47/175 (26.86%), Postives = 88/175 (50.29%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIM-EDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRD--DFNQIKS------EIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAV 678 L DTH VV+ F+ +GFS QQAE + + + N+ +++ DM + + Q E+ +++++++ +KKD+I F+ + ENE D I K ++ +N E+SR ++ I S +T +ID+++A L+T E ++ + +KY G+V Sbjct: 50 LFFDTHAVVRLFEENGFSTQQAEVMVNVLMRTTNSNMDVVYSDMVTKVHQ----EIMLQRVMSQIAAVKKDMIILEKSEFSALLAENE--------------DVIKKVHSDNMLDMNLEKSRVKELVSICGIISTAEQDRHFTETNMKIDTEVAGLKTMLESHKLDTIKYLAGSV 206
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Medaka
Match: zgc:165532 (mitochondrial calcium uniporter regulator 1 [Source:NCBI gene;Acc:101166999]) HSP 1 Score: 56.6102 bits (135), Expect = 3.872e-9 Identity = 46/177 (25.99%), Postives = 88/177 (49.72%), Query Frame = 1 Query: 181 LVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIM-EDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRD---------DFNQIKSE---IVKTQNRIDSQIANLRTSFEMYRNEVLKYAVG 672 L DTH VV+ F+ +GFS QQAE + + + N+ +++ DM + + Q E+ +++++++ +KKD+I F+ + ENE D I K ++ +N E+SR ++ F+Q + +T +ID+++A L+T E ++ + +KY G Sbjct: 60 LFFDTHAVVRLFEENGFSTQQAEVMVNVLMRTTNSNMDVVYSDMVTKVHQ----EIMLQRVMSQIAAVKKDMIILEKSEFSALLAENE--------------DVIKKVHSDNMLDMNLEKSRVKELGLIRLLFWVFSQTAEQDRHFTETNMKIDTEVAGLKTMLESHKLDTIKYLAG 218
BLAST of mitochondrial calcium uniporter regulator 1 vs. Planmine SMEST
Match: SMESG000000112.1 (SMESG000000112.1) HSP 1 Score: 353.984 bits (907), Expect = 2.112e-125 Identity = 176/176 (100.00%), Postives = 176/176 (100.00%), Query Frame = 1 Query: 178 MLVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAVIVIAVSFVA 705 MLVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAVIVIAVSFVA Sbjct: 1 MLVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAVIVIAVSFVA 176
BLAST of mitochondrial calcium uniporter regulator 1 vs. Planmine SMEST
Match: SMESG000000119.1 (SMESG000000119.1) HSP 1 Score: 170.629 bits (431), Expect = 4.727e-53 Identity = 81/182 (44.51%), Postives = 131/182 (71.98%), Query Frame = 1 Query: 160 VLSKRLMLVIDTHNVVQEFKTSGFSEQQAEALKHFALNLLNTQAEIMEDMNSHLFQRQEFELHNDQLLTEVSNIKKDLINSSTEYFNKMKDENEKSKMEIQLLRQQLKDEIDKTNNGMTSTINFEQSRTRDDFNQIKSEIVKTQNRIDSQIANLRTSFEMYRNEVLKYAVGAVIVIAVSFVA 705 L K +++++DTH+V+ + K+SGFSE++++A+K+FA+ L N QA+I+ + ++ EF L++ + LT V NI++D+ N STE F + +ENEK KM++ L+RQ + +E+ K NN ++ IN E+ R + NQ+++EI+KTQN ID+Q+ANLRTSFE YRN++ KYAVG +I + V+ Sbjct: 4 ALYKNMLMIMDTHSVINDLKSSGFSEEESKAIKNFAIKLFNAQADILSKTEKKVIKKHEFILYHKKYLTMVRNIQRDIFNLSTENFRTIYNENEKIKMDLLLIRQNIHEEVYKINNSVSININVERFRLAETHNQVRAEIIKTQNYIDTQVANLRTSFEQYRNDMFKYAVGTIITCFGAVVS 185 The following BLAST results are available for this feature:
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 3
BLAST of mitochondrial calcium uniporter regulator 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of mitochondrial calcium uniporter regulator 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 3
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of mitochondrial calcium uniporter regulator 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of mitochondrial calcium uniporter regulator 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 2
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30010958 ID=SMED30010958|Name=mitochondrial calcium uniporter regulator 1|organism=Schmidtea mediterranea sexual|type=transcript|length=769bpback to top protein sequence of SMED30010958-orf-1 >SMED30010958-orf-1 ID=SMED30010958-orf-1|Name=SMED30010958-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=212bp MIFYKTFKYIQLFNFNKFCTKVKHDVLSKRLMLVIDTHNVVQEFKTSGFSback to top Annotated Terms
The following terms have been associated with this transcript:
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