DNA ligase

Overview
NameDNA ligase
Smed IDSMED30010896
Length (bp)2459
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of DNA ligase (SMED30010896) t-SNE clustered cells

Violin plots show distribution of expression levels for DNA ligase (SMED30010896) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of DNA ligase (SMED30010896) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for DNA ligase (SMED30010896) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30010896

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30010896SMESG000046648.1 SmedASXL_013024SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X1 cellSMED30010896SMESG000046648.1 SmedASXL_013025SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30010896SMESG000046648.1 SmedASXL_013025SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
neoblastSMED30010896SMESG000046648.1 dd_Smed_v4_7382_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of DNA ligase vs. Ensembl Human
Match: LIG1 (DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598])

HSP 1 Score: 738.413 bits (1905), Expect = 0.000e+0
Identity = 350/660 (53.03%), Postives = 467/660 (70.76%), Query Frame = 3 
Query:  426 PSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNES------KLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKT--GESAINPYED 2381
            PS Y+P  N YH + DACWKP +K+PYLA+A+TFE IE  + RL +  TLSN +RSV+ LSP DLLP +YL LN + P  +G ELGVG+ V+  A+ QAT    +++ +   ++GD+GL+A N  S+QR ++ P  LT   VF K + I+  +G +S   KIDIIK L +A    E ++I RSL G+LR+ LAEQ+VLAAL QA++LTPP +          K +  ++ K  +++   I+K  FC+ P+ D +I  L ++G+  LP+HC + PG+P+KPMLAHP++G+SE+ +RF+ + FTCEYKYDG+RAQIH         +++IFSRNQE+NT KYPDI+  I +I +  SV S I+D+EAVAWDRE K I PFQ L+TRK+K+V+  +I++QVCLYAFDLIY N +SLV      RR++LRENF E  G FV ATSLD+ + ++I+EFLEQS+KD CEGLM+KTLD DATYEI+KRSHNWLKLKKDYLD +GDT+DLVVIGA  G GKRA +YG FLLA YD +SE  Q IC+LGTGF+DE+L+  +  LK  V   P      + + IPD W +P  VWE+K ADLS+SP + AA GLVD +KGISLRFPRFIR+REDK+ E ATT+ Q+A +YR Q  ++   GE + +  ED
Sbjct:  232 PSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGG----EVKIFSRNQEDNTGKYPDIISRIPKI-KLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQQGEDSGSDPED 886
[Close]
BLAST of DNA ligase vs. Ensembl Human
Match: LIG1 (DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598])

HSP 1 Score: 738.413 bits (1905), Expect = 0.000e+0
Identity = 350/660 (53.03%), Postives = 467/660 (70.76%), Query Frame = 3 
Query:  426 PSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNES------KLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKT--GESAINPYED 2381
            PS Y+P  N YH + DACWKP +K+PYLA+A+TFE IE  + RL +  TLSN +RSV+ LSP DLLP +YL LN + P  +G ELGVG+ V+  A+ QAT    +++ +   ++GD+GL+A N  S+QR ++ P  LT   VF K + I+  +G +S   KIDIIK L +A    E ++I RSL G+LR+ LAEQ+VLAAL QA++LTPP +          K +  ++ K  +++   I+K  FC+ P+ D +I  L ++G+  LP+HC + PG+P+KPMLAHP++G+SE+ +RF+ + FTCEYKYDG+RAQIH         +++IFSRNQE+NT KYPDI+  I +I +  SV S I+D+EAVAWDRE K I PFQ L+TRK+K+V+  +I++QVCLYAFDLIY N +SLV      RR++LRENF E  G FV ATSLD+ + ++I+EFLEQS+KD CEGLM+KTLD DATYEI+KRSHNWLKLKKDYLD +GDT+DLVVIGA  G GKRA +YG FLLA YD +SE  Q IC+LGTGF+DE+L+  +  LK  V   P      + + IPD W +P  VWE+K ADLS+SP + AA GLVD +KGISLRFPRFIR+REDK+ E ATT+ Q+A +YR Q  ++   GE + +  ED
Sbjct:  263 PSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGG----EVKIFSRNQEDNTGKYPDIISRIPKI-KLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQQGEDSGSDPED 917
[Close]
BLAST of DNA ligase vs. Ensembl Human
Match: LIG1 (DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598])

HSP 1 Score: 737.258 bits (1902), Expect = 0.000e+0
Identity = 350/660 (53.03%), Postives = 467/660 (70.76%), Query Frame = 3 
Query:  426 PSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNES------KLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKT--GESAINPYED 2381
            PS Y+P  N YH + DACWKP +K+PYLA+A+TFE IE  + RL +  TLSN +RSV+ LSP DLLP +YL LN + P  +G ELGVG+ V+  A+ QAT    +++ +   ++GD+GL+A N  S+QR ++ P  LT   VF K + I+  +G +S   KIDIIK L +A    E ++I RSL G+LR+ LAEQ+VLAAL QA++LTPP +          K +  ++ K  +++   I+K  FC+ P+ D +I  L ++G+  LP+HC + PG+P+KPMLAHP++G+SE+ +RF+ + FTCEYKYDG+RAQIH         +++IFSRNQE+NT KYPDI+  I +I +  SV S I+D+EAVAWDRE K I PFQ L+TRK+K+V+  +I++QVCLYAFDLIY N +SLV      RR++LRENF E  G FV ATSLD+ + ++I+EFLEQS+KD CEGLM+KTLD DATYEI+KRSHNWLKLKKDYLD +GDT+DLVVIGA  G GKRA +YG FLLA YD +SE  Q IC+LGTGF+DE+L+  +  LK  V   P      + + IPD W +P  VWE+K ADLS+SP + AA GLVD +KGISLRFPRFIR+REDK+ E ATT+ Q+A +YR Q  ++   GE + +  ED
Sbjct:  195 PSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGG----EVKIFSRNQEDNTGKYPDIISRIPKI-KLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQQGEDSGSDPED 849
[Close]
BLAST of DNA ligase vs. Ensembl Human
Match: LIG1 (DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598])

HSP 1 Score: 618.616 bits (1594), Expect = 0.000e+0
Identity = 288/539 (53.43%), Postives = 386/539 (71.61%), Query Frame = 3 
Query:  426 PSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNES------KLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRL 2024
            PS Y+P  N YH + DACWKP +K+PYLA+A+TFE IE  + RL +  TLSN +RSV+ LSP DLLP +YL LN + P  +G ELGVG+ V+  A+ QAT    +++ +   ++GD+GL+A N  S+QR ++ P  LT   VF K + I+  +G +S   KIDIIK L +A    E ++I RSL G+LR+ LAEQ+VLAAL QA++LTPP +          K +  ++ K  +++   I+K  FC+ P+ D +I  L ++G+  LP+HC + PG+P+KPMLAHP++G+SE+ +RF+ + FTCEYKYDG+RAQIH         +++IFSRNQE+NT KYPDI+  I +I +  SV S I+D+EAVAWDRE K I PFQ L+TRK+K+V+  +I++QVCLYAFDLIY N +SLV      RR++LRENF E  G FV ATSLD+ + ++I+EFLEQS+KD CEGLM+KTLD DATYEI+KRSHNWLKLKKDYLD +GDT+DLVVIGA  G GKRA +YG FLLA YD +SE  Q IC++
Sbjct:  263 PSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGG----EVKIFSRNQEDNTGKYPDIISRIPKI-KLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKV 796
[Close]
BLAST of DNA ligase vs. Ensembl Human
Match: LIG1 (DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598])

HSP 1 Score: 618.616 bits (1594), Expect = 0.000e+0
Identity = 288/539 (53.43%), Postives = 386/539 (71.61%), Query Frame = 3 
Query:  426 PSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNES------KLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRL 2024
            PS Y+P  N YH + DACWKP +K+PYLA+A+TFE IE  + RL +  TLSN +RSV+ LSP DLLP +YL LN + P  +G ELGVG+ V+  A+ QAT    +++ +   ++GD+GL+A N  S+QR ++ P  LT   VF K + I+  +G +S   KIDIIK L +A    E ++I RSL G+LR+ LAEQ+VLAAL QA++LTPP +          K +  ++ K  +++   I+K  FC+ P+ D +I  L ++G+  LP+HC + PG+P+KPMLAHP++G+SE+ +RF+ + FTCEYKYDG+RAQIH         +++IFSRNQE+NT KYPDI+  I +I +  SV S I+D+EAVAWDRE K I PFQ L+TRK+K+V+  +I++QVCLYAFDLIY N +SLV      RR++LRENF E  G FV ATSLD+ + ++I+EFLEQS+KD CEGLM+KTLD DATYEI+KRSHNWLKLKKDYLD +GDT+DLVVIGA  G GKRA +YG FLLA YD +SE  Q IC++
Sbjct:  263 PSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGG----EVKIFSRNQEDNTGKYPDIISRIPKI-KLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKV 796
[Close]
BLAST of DNA ligase vs. Ensembl Celegans
Match: lig-1 (DNA ligase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q27474])

HSP 1 Score: 602.053 bits (1551), Expect = 0.000e+0
Identity = 299/622 (48.07%), Postives = 416/622 (66.88%), Query Frame = 3 
Query:  480 WKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESKLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSM 2345
            W    K+PY   A T E IE  + + ++   L+ F   V+  SP DL  CVY+ +N++ P YEG ELGV E  +  A+ +AT   +  I   ++ +GDLG +A    S+Q+ L  P  LTVP+VF KL  I+  SG S+   K+D I  LLIA    E +++VR L GK+RI L EQ+VL+ALG A TL+   + K+ +    DSLK   D N   +KTA+C+CPNY+ LIE     G+  L + C + PG+P+KPMLAHP+KG+ EI +RF N   TCE+KYDGER QIH   D     +I I+SRNQENNT+KYPDI++ I   +    V S I+D+E VA D E   ILPFQ LSTRK+K+  + D  ++V ++ FDL+YFN + LV    R+RR++LR NF +  G F  ATS+D+ +TDEI+ F ++++++KCEGLMIKTLD +ATYEIS+RSH+WLK+KKDY+D +GDT+DLVV+GA  G GKR   YG +LL CY+  +E ++++C++GTGFTDEDL   Y  L++    K  S Y ++ +  PD  F P  V+E+K AD++ISP H+AA GL D  KGISLRFPRF+RIR+DK +++AT++ Q+ EMY+NQ++ 
Sbjct:   13 WAKGSKVPYKEFALTLEKIEELSGKKKVDE-LAQFFTKVLDFSPDDLTACVYMSVNQLGPSYEGLELGVAENSLIKAVAKATGRTEGKIKEDLRAKGDLGTVAQQSRSNQKMLAVPKALTVPTVFNKLTEIAKLSGTSAMNKKVDAISALLIACQGIEARFLVRMLAGKMRIGLGEQSVLSALGHAFTLSKITDQKV-RGDKLDSLK---DANVKRVKTAYCECPNYNRLIEVALTEGVEALVEKCKLSPGIPLKPMLAHPTKGIDEIMRRFRNQTMTCEWKYDGERGQIHKREDG----QIFIYSRNQENNTTKYPDIIEKISSCI-GDGVTSFIVDAEVVAID-EAGLILPFQVLSTRKRKNATD-DNGVKVVVFLFDLLYFNGEPLVRKPLRKRRELLRTNFKKIDGSFYFATSVDTNDTDEINSFFDEAVQNKCEGLMIKTLDTEATYEISRRSHSWLKMKKDYVDGVGDTLDLVVMGAYSGVGKRTGVYGGYLLGCYNPTTEEYESVCKIGTGFTDEDLAEQYKILQDKKIDKSPSYYQFDHTLKPDDTFSPYLVFEVKCADITISPRHKAASGLTDDGKGISLRFPRFLRIRDDKNSDDATSSEQVLEMYKNQEAF 622
[Close]
BLAST of DNA ligase vs. Ensembl Celegans
Match: lig-1 (DNA ligase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q27474])

HSP 1 Score: 150.214 bits (378), Expect = 3.960e-41
Identity = 81/196 (41.33%), Postives = 114/196 (58.16%), Query Frame = 3 
Query:  480 WKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESK 1067
            W    K+PY   A T E IE  + + ++   L+ F   V+  SP DL  CVY+ +N++ P YEG ELGV E  +  A+ +AT   +  I   ++ +GDLG +A    S+Q+ L  P  LTVP+VF KL  I+  SG S+   K+D I  LLIA    E +++VR L GK+RI L EQ+VL+ALG A TL+   + K
Sbjct:   13 WAKGSKVPYKEFALTLEKIEELSGKKKVDE-LAQFFTKVLDFSPDDLTACVYMSVNQLGPSYEGLELGVAENSLIKAVAKATGRTEGKIKEDLRAKGDLGTVAQQSRSNQKMLAVPKALTVPTVFNKLTEIAKLSGTSAMNKKVDAISALLIACQGIEARFLVRMLAGKMRIGLGEQSVLSALGHAFTLSKITDQK 207
[Close]
BLAST of DNA ligase vs. Ensembl Celegans
Match: lig-4 (LIGase [Source:UniProtKB/TrEMBL;Acc:Q95YE6])

HSP 1 Score: 65.0846 bits (157), Expect = 1.822e-10
Identity = 70/312 (22.44%), Postives = 129/312 (41.35%), Query Frame = 3 
Query: 1287 QRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPD----IVKLIKEI--LENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEV-----DIKIQVCLYAFDLIYFNDQSLVESSFRERRKILR--ENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTD------------------EDLDNFYSELKETVTRKPVSSYDYEKSQI 2129
            ++F    F  + K+DGE   +H   +     + + F+RN  + + +Y D    I KL   I    N   ES I + E + WD++TK +      ST     V        D   Q+ +  FDL+Y N +    +   +R ++L+      E+     +A   +    ++I +F E ++ +  EG+++K  D+         S+ W KLK     K  D +DL ++    G G+  N    +  A +D +++ ++       G +D                  E+L  FY +  + + R      D+E+ Q+
Sbjct:  247 EKFGGQKFFLQTKFDGENVLLHKKGN-----EYRWFTRNNNDFSKEYGDSSMAIGKLSSRIHSFFNKECESAIFNCELMLWDKKTKKLCRHNDASTTSDAQVLSFRHVKPDDNQQLTVVLFDLLYLNGKPFFGAPLHQRLEMLKIAPLKKEREDTIFVAKHEEGSKKEDIQQFFEIAMANNEEGIVVKRTDSVYVKGQRSASNGWFKLKPS-ASKDCD-LDLALVAVHPGAGR--NGKTLYRFAAFDEKTQDYKLCLSCSYGLSDTVREAIRFEYGQLLEEAPEEL-TFYGKRPKNIARGDGGYIDFERWQV 548
[Close]
BLAST of DNA ligase vs. Ensembl Celegans
Match: lig-4 (LIGase [Source:UniProtKB/TrEMBL;Acc:Q95YE6])

HSP 1 Score: 65.0846 bits (157), Expect = 1.822e-10
Identity = 70/312 (22.44%), Postives = 129/312 (41.35%), Query Frame = 3 
Query: 1287 QRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPD----IVKLIKEI--LENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEV-----DIKIQVCLYAFDLIYFNDQSLVESSFRERRKILR--ENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTD------------------EDLDNFYSELKETVTRKPVSSYDYEKSQI 2129
            ++F    F  + K+DGE   +H   +     + + F+RN  + + +Y D    I KL   I    N   ES I + E + WD++TK +      ST     V        D   Q+ +  FDL+Y N +    +   +R ++L+      E+     +A   +    ++I +F E ++ +  EG+++K  D+         S+ W KLK     K  D +DL ++    G G+  N    +  A +D +++ ++       G +D                  E+L  FY +  + + R      D+E+ Q+
Sbjct:  247 EKFGGQKFFLQTKFDGENVLLHKKGN-----EYRWFTRNNNDFSKEYGDSSMAIGKLSSRIHSFFNKECESAIFNCELMLWDKKTKKLCRHNDASTTSDAQVLSFRHVKPDDNQQLTVVLFDLLYLNGKPFFGAPLHQRLEMLKIAPLKKEREDTIFVAKHEEGSKKEDIQQFFEIAMANNEEGIVVKRTDSVYVKGQRSASNGWFKLKPS-ASKDCD-LDLALVAVHPGAGR--NGKTLYRFAAFDEKTQDYKLCLSCSYGLSDTVREAIRFEYGQLLEEAPEEL-TFYGKRPKNIARGDGGYIDFERWQV 548
[Close]
BLAST of DNA ligase vs. Ensembl Fly
Match: DNAlig1 (gene:FBgn0262619 transcript:FBtr0072132)

HSP 1 Score: 689.493 bits (1778), Expect = 0.000e+0
Identity = 346/655 (52.82%), Postives = 457/655 (69.77%), Query Frame = 3 
Query:  435 YDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNE-SKLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKTGESAINPYE-DDEFY 2393
            YDP  + YH + +A WK  +  PYLALA+TF+VIE T  RL++  TLSNF  SV+ +SP+DL+P VYL +N++AP YEG ELGV E  +  A+ +AT  +   I S+ +  GDLG++A     SQR + QPA L V  VF+KL+ I+  SG+S    K+D++ N+ +A    E ++ +RSL+GKLRI +AEQ++L AL  AI L   N       S+  D  K  I   T ++KTA+CQCPNYD++I ++ KY I  L + C + PG+P++PMLA P+KGV E+F+RF     TCE+KYDGERAQIH     N K +I IFSRN ENNT+KYPD++     +L+   V+S IIDSE VAWD E K ILPFQ LSTRK+K+V+  +IK+QVC+Y FDL+Y N  +LV  +  ERRK+L E+F E  G +  AT+LD+ + DE+ +FLE+SIK  CEGLM+KTLD +ATYEI+KRS NWLKLKKDYL  +GD++DLVVIG   G G+R   YG FLLACYD+E+E +Q+IC++GTGFTDEDL      L + VT    S Y Y+ S  PD WFEP  VWE+K ADLS+SP HRAA+G+VD E+GISLRFPRFIRIR+DK +ENAT A Q+A MY++QD +K  + +    E +DEFY
Sbjct:  104 YDPSADSYHPLKNAYWKDKKVTPYLALARTFQVIEETKGRLKMIDTLSNFFCSVMLVSPEDLVPSVYLSINQLAPAYEGLELGVAETTLMKAICKATGRNLAHIKSQTQLTGDLGIVAEQSRVSQRMMFQPAPLNVRDVFRKLREIAKLSGQS----KMDLVYNMFVACRSSEARFFIRSLIGKLRIGIAEQSLLTAL--AIGLVKKNHIDDCKASKVPDVYKDEIVDTTLLLKTAYCQCPNYDIIIPAILKYDIKELQERCPMHPGMPLRPMLAQPTKGVHEVFERFGGMQITCEWKYDGERAQIH----RNEKGEISIFSRNSENNTAKYPDLIARSTALLKGD-VKSYIIDSEIVAWDVERKQILPFQVLSTRKRKNVDIEEIKVQVCVYIFDLLYINGTALVTKNLSERRKLLLEHFQEVEGEWKFATALDTNDIDEVQQFLEESIKGNCEGLMVKTLDEEATYEIAKRSRNWLKLKKDYLSNVGDSLDLVVIGGYKGKGRRTGTYGGFLLACYDTENEEYQSICKIGTGFTDEDLQTHSEFLGKHVTSAAKSYYRYDPSLEPDHWFEPVQVWEVKCADLSLSPIHRAAIGIVDGERGISLRFPRFIRIRDDKNSENATDANQVAHMYQSQDQVKNNQKSSTQMEMEDEFY 747
[Close]
BLAST of DNA ligase vs. Ensembl Fly
Match: DNAlig3 (gene:FBgn0286075 transcript:FBtr0082600)

HSP 1 Score: 180.259 bits (456), Expect = 7.721e-47
Identity = 124/375 (33.07%), Postives = 188/375 (50.13%), Query Frame = 3 
Query: 1233 VPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNT-SKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYL--DKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGF---TDEDLDNFYSELKETVTRKPVSSYDY-EKSQIPDCWFEPKY---VWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMY 2327
             PI PMLA P K V + F++     ++ E KYDGER QIH   +       + FSRN +     K   + K I +          I+DSE +  D +T ++LPF  L   KK+          VCL+ FD I ++ + L +  FR+RR+IL +N         L+ S     T E++    + +    EG+++K+    +TY+  KR  NWLK+KKDYL   KM DT DLVV+GA YG+GK+      FL+ CYD+   L++T+ ++ +G    T+ ++     +L E      + S+    KS +PD   +      VWEI  A+ + S  H A+        GIS+RFPR  R R DK A+ A     + +++
Sbjct:  253 TPISPMLASPCKSVEDAFKKSPTGLYS-EIKYDGERVQIHKQGN-----DFKFFSRNLKPVVDHKIRALKKYIPQAFPGGG--EMILDSEIILVDTDTGALLPFGSLGAHKKQTFANA----AVCLFVFDCILYDGEDLTQLPFRKRREILEQNIQPIKSHVQLSESEFLKTTRELAAMTARVLHANLEGVVLKS--PTSTYQPGKR--NWLKVKKDYLFDGKMADTADLVVLGAWYGSGKKGGTLSIFLMGCYDAFGRLWKTVTKVHSGLDDATNAEVHKSLIKLTERADANAIPSWLLCSKSLVPDVLAKDPMKMPVWEITGAEFTKSDAHTAS--------GISVRFPRITRRRSDKSAKEANDLAHLEDLF 603
[Close]
BLAST of DNA ligase vs. Ensembl Fly
Match: DNAlig4 (gene:FBgn0030506 transcript:FBtr0073847)

HSP 1 Score: 100.908 bits (250), Expect = 2.169e-21
Identity = 133/559 (23.79%), Postives = 218/559 (39.00%), Query Frame = 3 
Query:  771 DLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAAL--------------GQAITLTPPNESKLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKG-VSEIFQRFDNSD-FTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYP---DIVKLIKEI--LENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEV-----DIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKR-SHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYD-------SESELFQTICRLGTGFTDEDLDN--FYSELKETVTRKPVSSYDY---EKSQIPDCWFEPK--YVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEM 2324
            D G + Y++    R    P+ L +  + Q L  I+    +      I   +     +S  E+K+++R LL  L + + EQ +   L              G    L     + LD S + DS   +   N   +   F Q                              I+PML     G + E+ Q    SD    E K DGER Q+H+      + +    SRN  + T  +    D   L  ++  L    +ES I+D E + WD          KL  R+K +  +V     +   Q C   +DL+YFN QSL++ ++ +R   L++   E+ G   L  +    +  E +E  +Q++    EG+++K     + Y+   R    W K K DY+  +    D+++IGA Y   ++     +FLL           +  E+F +I  +        + N        + V   P   + Y   E+S  PD W EP+   + ++KAADL       A  G     K  SL FPR    R+DK      T ++  ++
Sbjct:  121 DYGDVVYSVLKP-RCFNPPSNLRLKEIHQMLDTIANEDTEVKQQQLIRFTEQ----ASPEEQKWLIRLLLKSLGLGIGEQKIFGVLHPKAQDIYQRCSDLGHVCNLLADRTTDLDASSSKDSKAAVKFVNLNSVIRPFHQ------------------------------IRPMLCERFPGDIQELMQ----SDVLYLETKMDGERFQLHID-----RGRFMYISRNGVDYTRNFGHSYDHGTLTPKLRGLLPLGLESIILDGEMMVWDT--------NKLRFREKGENTDVKSLKPEGSWQPCFVVYDLLYFNGQSLLDHTYIQRAYKLQKLIVEQSGVLQLMRARKIGSVQEFNELFQQALDSHAEGIVLKK--QGSRYQPGVRLGGGWYKDKADYIKGLITEFDVLIIGAFY--NRKRTFVDSFLLGVLQPAPPGSSNRPEVF-SIGVVANNTKQRGVLNHTLKPHWHDVVNEPPPLWFHYKPKERSGCPDLWIEPQNSVILQVKAADL-------APNGAFFTRK--SLHFPRTEMKRDDKTWSECMTLKEFNDL 613
[Close]
BLAST of DNA ligase vs. Ensembl Zebrafish
Match: lig1 (ligase I, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB-GENE-110404-2])

HSP 1 Score: 771.926 bits (1992), Expect = 0.000e+0
Identity = 374/666 (56.16%), Postives = 486/666 (72.97%), Query Frame = 3 
Query:  372 TDDLNQTEIETVEKVNK-IPSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNE----SKLD--KSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMK 2348
            +D + Q E ++ + V+  + S+YDP    YH I+ ACWK  +K+PYLA+A+TFE IE  + RL+   TLSNF+RSVI LSP DLL CVYLCLN++ P Y+G ELG+GE V+  A+ QAT      I +  +++GDLGL+A +  S+QR +  PA LT   VF KLK I+  SG S+   KIDIIK L +A    E +YIVRSL GKLRI LAEQ+VLAAL QA+ LTPP +    + LD  K  + ++ +  +++   I+K  +C+ PNYD +I  L K GI  LP+HC + PGVP++PMLAHP+KGV E+ +RFD + FTCEYKYDGERAQIH+    NG+  ++IFSRNQE+NTSKYPDI+  I ++ +  SV SC++DSEAVAWDRE K I PFQ L+TRK+KDV+  +IK+QVC+YAFDL+Y N +SLV     +RR +LRE+F EK G FV A SLD+ NT+ I+EFLEQS++D CEGLM+KTL+  ATYEI+KRSHNWLKLKKDYL+ +GDTVDL VIGA  G GKRA  YG FLLACYD E+E FQ++C++GTGF DEDL+  Y+ LKE +  KP   Y  ++S  PD W E   VWE+K ADLS+SP ++AA+GLVD EKGISLRFPRF+RIR+DKK E+ATT  QIA++Y+ Q  ++
Sbjct:  386 SDVVEQKEKKSEKGVDSAVQSQYDPSRAHYHPIDHACWKKGQKVPYLAVARTFEKIEEDSGRLKNIETLSNFLRSVILLSPDDLLCCVYLCLNQLGPAYQGLELGIGETVLMKAVAQATGRQLDKIKAEAQEKGDLGLVAESSRSNQRMMFAPANLTAGGVFNKLKEIAHMSGNSAMNKKIDIIKGLFVACRFSEARYIVRSLAGKLRIGLAEQSVLAALSQAVCLTPPGQEFPPAVLDAGKGMSTENRRVFLEEKALILKQTYCEMPNYDAIIPVLLKEGIDELPNHCKLTPGVPLRPMLAHPTKGVGEVMKRFDEASFTCEYKYDGERAQIHILE--NGE--VRIFSRNQEDNTSKYPDIISRIPQV-KKESVRSCVLDSEAVAWDREKKQIQPFQVLTTRKRKDVDASEIKVQVCVYAFDLLYLNGESLVREPLSKRRALLRESFVEKEGEFVFARSLDADNTETIAEFLEQSVRDSCEGLMVKTLEKHATYEIAKRSHNWLKLKKDYLEGVGDTVDLCVIGAYLGKGKRAGGYGGFLLACYDEENEEFQSVCKIGTGFKDEDLEQHYNFLKEHILPKPRPYYRVDQSAEPDVWLEAVQVWEVKCADLSLSPVYKAAMGLVDPEKGISLRFPRFLRIRDDKKPEDATTGSQIADLYKKQQQIQ 1046
[Close]
BLAST of DNA ligase vs. Ensembl Zebrafish
Match: lig1 (ligase I, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB-GENE-110404-2])

HSP 1 Score: 771.926 bits (1992), Expect = 0.000e+0
Identity = 374/666 (56.16%), Postives = 486/666 (72.97%), Query Frame = 3 
Query:  372 TDDLNQTEIETVEKVNK-IPSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNE----SKLD--KSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMK 2348
            +D + Q E ++ + V+  + S+YDP    YH I+ ACWK  +K+PYLA+A+TFE IE  + RL+   TLSNF+RSVI LSP DLL CVYLCLN++ P Y+G ELG+GE V+  A+ QAT      I +  +++GDLGL+A +  S+QR +  PA LT   VF KLK I+  SG S+   KIDIIK L +A    E +YIVRSL GKLRI LAEQ+VLAAL QA+ LTPP +    + LD  K  + ++ +  +++   I+K  +C+ PNYD +I  L K GI  LP+HC + PGVP++PMLAHP+KGV E+ +RFD + FTCEYKYDGERAQIH+    NG+  ++IFSRNQE+NTSKYPDI+  I ++ +  SV SC++DSEAVAWDRE K I PFQ L+TRK+KDV+  +IK+QVC+YAFDL+Y N +SLV     +RR +LRE+F EK G FV A SLD+ NT+ I+EFLEQS++D CEGLM+KTL+  ATYEI+KRSHNWLKLKKDYL+ +GDTVDL VIGA  G GKRA  YG FLLACYD E+E FQ++C++GTGF DEDL+  Y+ LKE +  KP   Y  ++S  PD W E   VWE+K ADLS+SP ++AA+GLVD EKGISLRFPRF+RIR+DKK E+ATT  QIA++Y+ Q  ++
Sbjct:  386 SDVVEQKEKKSEKGVDSAVQSQYDPSRAHYHPIDHACWKKGQKVPYLAVARTFEKIEEDSGRLKNIETLSNFLRSVILLSPDDLLCCVYLCLNQLGPAYQGLELGIGETVLMKAVAQATGRQLDKIKAEAQEKGDLGLVAESSRSNQRMMFAPANLTAGGVFNKLKEIAHMSGNSAMNKKIDIIKGLFVACRFSEARYIVRSLAGKLRIGLAEQSVLAALSQAVCLTPPGQEFPPAVLDAGKGMSTENRRVFLEEKALILKQTYCEMPNYDAIIPVLLKEGIDELPNHCKLTPGVPLRPMLAHPTKGVGEVMKRFDEASFTCEYKYDGERAQIHILE--NGE--VRIFSRNQEDNTSKYPDIISRIPQV-KKESVRSCVLDSEAVAWDREKKQIQPFQVLTTRKRKDVDASEIKVQVCVYAFDLLYLNGESLVREPLSKRRALLRESFVEKEGEFVFARSLDADNTETIAEFLEQSVRDSCEGLMVKTLEKHATYEIAKRSHNWLKLKKDYLEGVGDTVDLCVIGAYLGKGKRAGGYGGFLLACYDEENEEFQSVCKIGTGFKDEDLEQHYNFLKEHILPKPRPYYRVDQSAEPDVWLEAVQVWEVKCADLSLSPVYKAAMGLVDPEKGISLRFPRFLRIRDDKKPEDATTGSQIADLYKKQQQIQ 1046
[Close]
BLAST of DNA ligase vs. Ensembl Zebrafish
Match: lig1 (ligase I, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB-GENE-110404-2])

HSP 1 Score: 739.184 bits (1907), Expect = 0.000e+0
Identity = 363/666 (54.50%), Postives = 474/666 (71.17%), Query Frame = 3 
Query:  372 TDDLNQTEIETVEKVNK-IPSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNE----SKLD--KSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMK 2348
            +D + Q E ++ + V+  + S+YDP    YH I+ ACWK  +       ++ F        +L+   TLSNF+RSVI LSP DLL CVYLCLN++ P Y+G ELG+GE V+  A+ QAT      I +  +++GDLGL+A +  S+QR +  PA LT   VF KLK I+  SG S+   KIDIIK L +A    E +YIVRSL GKLRI LAEQ+VLAAL QA+ LTPP +    + LD  K  + ++ +  +++   I+K  +C+ PNYD +I  L K GI  LP+HC + PGVP++PMLAHP+KGV E+ +RFD + FTCEYKYDGERAQIH+    NG+  ++IFSRNQE+NTSKYPDI+  I ++ +  SV SC++DSEAVAWDRE K I PFQ L+TRK+KDV+  +IK+QVC+YAFDL+Y N +SLV     +RR +LRE+F EK G FV A SLD+ NT+ I+EFLEQS++D CEGLM+KTL+  ATYEI+KRSHNWLKLKKDYL+ +GDTVDL VIGA  G GKRA  YG FLLACYD E+E FQ++C++GTGF DEDL+  Y+ LKE +  KP   Y  ++S  PD W E   VWE+K ADLS+SP ++AA+GLVD EKGISLRFPRF+RIR+DKK E+ATT  QIA++Y+ Q  ++
Sbjct:  386 SDVVEQKEKKSEKGVDSAVQSQYDPSRAHYHPIDHACWKKGQNPTISDFSQNF--FNHPYSQLKNIETLSNFLRSVILLSPDDLLCCVYLCLNQLGPAYQGLELGIGETVLMKAVAQATGRQLDKIKAEAQEKGDLGLVAESSRSNQRMMFAPANLTAGGVFNKLKEIAHMSGNSAMNKKIDIIKGLFVACRFSEARYIVRSLAGKLRIGLAEQSVLAALSQAVCLTPPGQEFPPAVLDAGKGMSTENRRVFLEEKALILKQTYCEMPNYDAIIPVLLKEGIDELPNHCKLTPGVPLRPMLAHPTKGVGEVMKRFDEASFTCEYKYDGERAQIHILE--NGE--VRIFSRNQEDNTSKYPDIISRIPQV-KKESVRSCVLDSEAVAWDREKKQIQPFQVLTTRKRKDVDASEIKVQVCVYAFDLLYLNGESLVREPLSKRRALLRESFVEKEGEFVFARSLDADNTETIAEFLEQSVRDSCEGLMVKTLEKHATYEIAKRSHNWLKLKKDYLEGVGDTVDLCVIGAYLGKGKRAGGYGGFLLACYDEENEEFQSVCKIGTGFKDEDLEQHYNFLKEHILPKPRPYYRVDQSAEPDVWLEAVQVWEVKCADLSLSPVYKAAMGLVDPEKGISLRFPRFLRIRDDKKPEDATTGSQIADLYKKQQQIQ 1044
[Close]
BLAST of DNA ligase vs. Ensembl Zebrafish
Match: lig3 (ligase III, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB-GENE-030131-8453])

HSP 1 Score: 187.963 bits (476), Expect = 6.894e-49
Identity = 132/385 (34.29%), Postives = 188/385 (48.83%), Query Frame = 3 
Query: 1233 VPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENS--SVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDK--MGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFE------PKY---------VWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYR 2330
             P++PMLA   K +    ++  N  ++ E KYDGER Q+H     NG      FSR+ +      P  V   K+ +  +     S I+D+E +  D +T   LPF  L   KK    +     QV L+ FD IYFN  SL++    ERRK L +N  E P   + +         +++E + + I++  EGL++K  D    YE  KR  +WLK+KKDYL++  M DT DLVV+GA YG G       +FL+ CYD ES  + T+ +   GF D  LD    +L        V     + S+IP  W +      P +         VWEI  A+ S S  H A         GIS+RFPR  R+R+DK  + AT  +Q+ E+YR
Sbjct:  478 TPVQPMLAEACKSIEYAMKKCPNGMYS-EIKYDGERVQVH----KNGNH-FSYFSRSLK---PVLPHKVAHFKDFIPQAFAGGHSMILDAEVLLIDTKTSKPLPFGTLGVHKKAAFQDA----QVGLFVFDCIYFNGVSLMDKPLCERRKFLHDNMVEVPNRILFSEMKHVTRAPDLAEMITRVIREGLEGLVLK--DIKGLYEPGKR--HWLKVKKDYLNEGAMADTADLVVLGAFYGKGSNGGIMSSFLMGCYDPESRKWCTVTKCSGGFDDAMLDRLQKDLD-------VIKIGKDPSKIPG-WLKIVKNYYPDFIIRDPQKAPVWEITGAEFSKSEMHTA--------DGISIRFPRCTRMRDDKDWKTATNLQQLKELYR 829
[Close]
BLAST of DNA ligase vs. Ensembl Zebrafish
Match: lig4 (ligase IV, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB-GENE-070820-10])

HSP 1 Score: 142.51 bits (358), Expect = 2.091e-34
Identity = 132/556 (23.74%), Postives = 252/556 (45.32%), Query Frame = 3 
Query:  768 GDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESKLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYP------DIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEV--DIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSES-----ELFQTICRLGTGFTDEDLDNFYSELK---ETVTRKPVSSYDYEKSQIPDCWFEPK--YVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKTGESAINPYED 2381
            GD  L+AY +   ++       L++  V   L  ++  +           + +L+  SS  E+K+++R +L  +++ ++++TVL                    Q F    P     T  +     Q  +  + +  +            SI      KPMLA  +  + +I ++  N  F  E K DGER Q+H + D       + ++RN    T ++        +   I  +  +  V +CI+D E +A++ +T++ +  QK S   K D+  +  D  +Q C   FD++  N+Q   +   ++R + L   F+   G   L +  +     E+   L ++I ++ EG+M+K  D  + Y+  KR   WLK+K +Y+D + D +DL+++G  +G G+R+     FL A  +  S      +F T+CR+G+G+T ++L +   +L    +   +    +     ++ P+ + EP+   + ++KAA++  S  ++            +LRFPR  RIREDK+     T   + + +R++ S K     +N +ED
Sbjct:  128 GDFALMAYFV--LKKRCTSQGNLSIKEVNDFLDSVAINNASKQKDQVKKSLLHLITQSSALEQKWLIRMILKDMKLGISKETVL--------------------QVFHPDAPEFYNVTTDLNKVCRQLHDPSVSLSEV------------SIDLFSAFKPMLAAVA-NIRQIEKQMGNRPFYIETKLDGERIQLHKAGDV-----YKYYTRNSYEYTQQFGASPLEGSLTPYIHNVF-SPHVVNCILDGEMMAYNPKTETFM--QKGS---KFDIKRLVDDSDLQTCFCVFDVLLINNQKFGKEPLKKRYESLETVFSPIKGRIHLVSKSEGRTMQEVVNSLNEAIDNREEGIMVK--DPMSIYKPDKRGEGWLKIKPEYVDGLMDELDLLIVGGYWGKGRRSGMLSHFLCAVAEVPSPGEKPTVFHTLCRIGSGYTLKELYDLGVKLAKHWKVYNKNNPPAAILCGTEKPEVYIEPRNSVILQVKAAEIVTSEMYKT---------DCTLRFPRIERIREDKEWHQCMTLDDLNQ-FRSKASGKLASRHLNIHED 625
[Close]
BLAST of DNA ligase vs. Ensembl Xenopus
Match: golga5 (golgin A5 [Source:Xenbase;Acc:XB-GENE-1014825])

HSP 1 Score: 768.074 bits (1982), Expect = 0.000e+0
Identity = 367/645 (56.90%), Postives = 474/645 (73.49%), Query Frame = 3 
Query:  426 PSE----YDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESK------LDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYR 2330
            PSE    Y+P  + YH INDACW   +K+PYLA+A+TFE IE  + RL+   TLSNF+RSVI L+P DLLPC+YLCLN++ P YEG ELG+GE ++  A+ QAT    + I S  +++GDLGL+A +  S+QR +  P KL    VF KLK I+  +G +S   KIDIIK L +A    E +YI RSL GKLRI LAEQ+VL+A+ QA+ LTPP            K  + D+ K  I+    I+K  FC+ PNYD +I  L ++GI +LP HC + PG+P+KPMLAHP+KG+ E+ +RFD + FTCEYKYDGERAQIH+    NG+  + I+SRNQENNT+KYPDI+  I +I +  SV+SCI+D+EAVAWD E K I PFQ L+TRK+KDV+  +IK+QVC+YAFD++Y N +SLV+  F +RR++LR++F E  G F+ AT +D+ NTDEISEFL+QSIKD CEGLM+KTL+ DATYEI+KRSHNWLKLKKDYL+ +GDT+DLVVIGA  G GKR   YG FLLA YD ESE +QTIC++GTGFTDEDL+  Y+ LK+ V   P S Y ++ +  PD WF+P  VWE+K ADLSISP H+AA+GLV+ EKGISLRFPRF+RIR+DKK E AT + Q+A++YR
Sbjct:  348 PSEDQAVYNPSKSSYHPINDACWSNGQKVPYLAVARTFERIEEESARLKNIETLSNFLRSVIALTPGDLLPCIYLCLNRLGPAYEGLELGIGETILMKAVAQATGRQLEKIKSEAQEKGDLGLVAESSRSNQRTMFTPPKLMASGVFSKLKDIARMTGNASMNKKIDIIKGLFVACRHSEARYIARSLGGKLRIGLAEQSVLSAIAQAVCLTPPGHDAPPTVMDAGKGMSTDARKSWIEDKAMILKQTFCELPNYDAIIPILLEHGIDDLPKHCRLTPGIPLKPMLAHPTKGIGEVLKRFDEAAFTCEYKYDGERAQIHILE--NGE--VHIYSRNQENNTTKYPDIISRIPKI-KKESVKSCILDTEAVAWDPEKKQIQPFQVLTTRKRKDVDASEIKVQVCVYAFDMLYLNGESLVKEPFAKRRQLLRDSFLETEGEFMFATYMDTSNTDEISEFLDQSIKDSCEGLMVKTLEQDATYEIAKRSHNWLKLKKDYLEGVGDTLDLVVIGAYLGKGKRTGIYGGFLLASYDEESEEYQTICKIGTGFTDEDLEKHYNYLKDHVIDSPRSYYRWDSATEPDHWFDPVQVWEVKCADLSISPVHKAALGLVEDEKGISLRFPRFLRIRDDKKPEEATNSFQVADLYR 987
[Close]
BLAST of DNA ligase vs. Ensembl Xenopus
Match: golga5 (golgin A5 [Source:Xenbase;Acc:XB-GENE-1014825])

HSP 1 Score: 763.837 bits (1971), Expect = 0.000e+0
Identity = 371/676 (54.88%), Postives = 483/676 (71.45%), Query Frame = 3 
Query:  345 PKKELNCIKTDDLNQTEIETVEKVNKIPSE----YDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESK------LDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDS 2342
            PKK    IKT+   +   E    +   PSE    Y+P  + YH INDACW   +K+PYLA+A+TFE IE  + RL+   TLSNF+RSVI L+P DLLPC+YLCLN++ P YEG ELG+GE ++  A+ QAT    + I S  +++GDLGL+A +  S+QR +  P KL    VF KLK I+  +G +S   KIDIIK L +A    E +YI RSL GKLRI LAEQ+VL+A+ QA+ LTPP            K  + D+ K  I+    I+K  FC+ PNYD +I  L ++GI +LP HC + PG+P+KPMLAHP+KG+ E+ +RFD + FTCEYKYDGERAQIH+  +     ++ I+SRNQENNT+KYPDI+  I +I +  SV+SCI+D+EAVAWD E K I PFQ L+TRK+KDV+  +IK+QVC+YAFD++Y N +SLV+  F +RR++LR++F E  G F+ AT +D+ NTDEISEFL+QSIKD CEGLM+KTL+ DATYEI+KRSHNWLKLKKDYL+ +GDT+DLVVIGA  G GKR   YG FLLA YD ESE +QTIC++GTGFTDEDL+  Y+ LK+ V   P S Y ++ +  PD WF+P  VWE+K ADLSISP H+AA+GLV+ EKGISLRFPRF+RIR+DKK E AT + Q+   + +Q+S
Sbjct:  247 PKKP--AIKTEKKEEIMNEKNATIKPEPSEDQAVYNPSKSSYHPINDACWSNGQKVPYLAVARTFERIEEESARLKNIETLSNFLRSVIALTPGDLLPCIYLCLNRLGPAYEGLELGIGETILMKAVAQATGRQLEKIKSEAQEKGDLGLVAESSRSNQRTMFTPPKLMASGVFSKLKDIARMTGNASMNKKIDIIKGLFVACRHSEARYIARSLGGKLRIGLAEQSVLSAIAQAVCLTPPGHDAPPTVMDAGKGMSTDARKSWIEDKAMILKQTFCELPNYDAIIPILLEHGIDDLPKHCRLTPGIPLKPMLAHPTKGIGEVLKRFDEAAFTCEYKYDGERAQIHILENG----EVHIYSRNQENNTTKYPDIISRIPKI-KKESVKSCILDTEAVAWDPEKKQIQPFQVLTTRKRKDVDASEIKVQVCVYAFDMLYLNGESLVKEPFAKRRQLLRDSFLETEGEFMFATYMDTSNTDEISEFLDQSIKDSCEGLMVKTLEQDATYEIAKRSHNWLKLKKDYLEGVGDTLDLVVIGAYLGKGKRTGIYGGFLLASYDEESEEYQTICKIGTGFTDEDLEKHYNYLKDHVIDSPRSYYRWDSATEPDHWFDPVQVWEVKCADLSISPVHKAALGLVEDEKGISLRFPRFLRIRDDKKPEEATNSFQLVRQHNSQNS 915
[Close]
BLAST of DNA ligase vs. Ensembl Xenopus
Match: golga5 (golgin A5 [Source:Xenbase;Acc:XB-GENE-1014825])

HSP 1 Score: 759.214 bits (1959), Expect = 0.000e+0
Identity = 364/641 (56.79%), Postives = 470/641 (73.32%), Query Frame = 3 
Query:  426 PSE----YDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESK------LDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIA 2318
            PSE    Y+P  + YH INDACW   +K+PYLA+A+TFE IE  + RL+   TLSNF+RSVI L+P DLLPC+YLCLN++ P YEG ELG+GE ++  A+ QAT    + I S  +++GDLGL+A +  S+QR +  P KL    VF KLK I+  +G +S   KIDIIK L +A    E +YI RSL GKLRI LAEQ+VL+A+ QA+ LTPP            K  + D+ K  I+    I+K  FC+ PNYD +I  L ++GI +LP HC + PG+P+KPMLAHP+KG+ E+ +RFD + FTCEYKYDGERAQIH+    NG+  + I+SRNQENNT+KYPDI+  I +I +  SV+SCI+D+EAVAWD E K I PFQ L+TRK+KDV+  +IK+QVC+YAFD++Y N +SLV+  F +RR++LR++F E  G F+ AT +D+ NTDEISEFL+QSIKD CEGLM+KTL+ DATYEI+KRSHNWLKLKKDYL+ +GDT+DLVVIGA  G GKR   YG FLLA YD ESE +QTIC++GTGFTDEDL+  Y+ LK+ V   P S Y ++ +  PD WF+P  VWE+K ADLSISP H+AA+GLV+ EKGISLRFPRF+RIR+DKK E AT + Q++
Sbjct:  433 PSEDQAVYNPSKSSYHPINDACWSNGQKVPYLAVARTFERIEEESARLKNIETLSNFLRSVIALTPGDLLPCIYLCLNRLGPAYEGLELGIGETILMKAVAQATGRQLEKIKSEAQEKGDLGLVAESSRSNQRTMFTPPKLMASGVFSKLKDIARMTGNASMNKKIDIIKGLFVACRHSEARYIARSLGGKLRIGLAEQSVLSAIAQAVCLTPPGHDAPPTVMDAGKGMSTDARKSWIEDKAMILKQTFCELPNYDAIIPILLEHGIDDLPKHCRLTPGIPLKPMLAHPTKGIGEVLKRFDEAAFTCEYKYDGERAQIHILE--NGE--VHIYSRNQENNTTKYPDIISRIPKI-KKESVKSCILDTEAVAWDPEKKQIQPFQVLTTRKRKDVDASEIKVQVCVYAFDMLYLNGESLVKEPFAKRRQLLRDSFLETEGEFMFATYMDTSNTDEISEFLDQSIKDSCEGLMVKTLEQDATYEIAKRSHNWLKLKKDYLEGVGDTLDLVVIGAYLGKGKRTGIYGGFLLASYDEESEEYQTICKIGTGFTDEDLEKHYNYLKDHVIDSPRSYYRWDSATEPDHWFDPVQVWEVKCADLSISPVHKAALGLVEDEKGISLRFPRFLRIRDDKKPEEATNSFQVS 1068
[Close]
BLAST of DNA ligase vs. Ensembl Xenopus
Match: golga5 (golgin A5 [Source:Xenbase;Acc:XB-GENE-1014825])

HSP 1 Score: 756.133 bits (1951), Expect = 0.000e+0
Identity = 369/674 (54.75%), Postives = 485/674 (71.96%), Query Frame = 3 
Query:  384 NQTEIETVEKVNKIPSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESK------LDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQ--IAEMYRNQDS--MKTGESAINPY 2375
            ++T +E   K  K  + Y+P  + YH INDACW   +K+PYLA+A+TFE IE  + RL+   TLSNF+RSVI L+P DLLPC+YLCLN++ P YEG ELG+GE ++  A+ QAT    + I S  +++GDLGL+A +  S+QR +  P KL    VF KLK I+  +G +S   KIDIIK L +A    E +YI RSL GKLRI LAEQ+VL+A+ QA+ LTPP            K  + D+ K  I+    I+K  FC+ PNYD +I  L ++GI +LP HC + PG+P+KPMLAHP+KG+ E+ +RFD + FTCEYKYDGERAQIH+  +     ++ I+SRNQENNT+KYPDI+  I +I +  SV+SCI+D+EAVAWD E K I PFQ L+TRK+KDV+  +IK+QVC+YAFD++Y N +SLV+  F +RR++LR++F E  G F+ AT +D+ NTDEISEFL+QSIKD CEGLM+KTL+ DATYEI+KRSHNWLKLKKDYL+ +GDT+DLVVIGA  G GKR   YG FLLA YD ESE +QTIC++GTGFTDEDL+  Y+ LK+ V   P S Y ++ +  PD WF+P  VWE+K ADLSISP H+AA+GLV+ EKGISLRFPRF+RIR+DKK E AT + Q  I +M  ++ S  M +  +A++ Y
Sbjct:   33 SETSLEASPKPKKT-AVYNPSKSSYHPINDACWSNGQKVPYLAVARTFERIEEESARLKNIETLSNFLRSVIALTPGDLLPCIYLCLNRLGPAYEGLELGIGETILMKAVAQATGRQLEKIKSEAQEKGDLGLVAESSRSNQRTMFTPPKLMASGVFSKLKDIARMTGNASMNKKIDIIKGLFVACRHSEARYIARSLGGKLRIGLAEQSVLSAIAQAVCLTPPGHDAPPTVMDAGKGMSTDARKSWIEDKAMILKQTFCELPNYDAIIPILLEHGIDDLPKHCRLTPGIPLKPMLAHPTKGIGEVLKRFDEAAFTCEYKYDGERAQIHILENG----EVHIYSRNQENNTTKYPDIISRIPKI-KKESVKSCILDTEAVAWDPEKKQIQPFQVLTTRKRKDVDASEIKVQVCVYAFDMLYLNGESLVKEPFAKRRQLLRDSFLETEGEFMFATYMDTSNTDEISEFLDQSIKDSCEGLMVKTLEQDATYEIAKRSHNWLKLKKDYLEGVGDTLDLVVIGAYLGKGKRTGIYGGFLLASYDEESEEYQTICKIGTGFTDEDLEKHYNYLKDHVIDSPRSYYRWDSATEPDHWFDPVQVWEVKCADLSISPVHKAALGLVEDEKGISLRFPRFLRIRDDKKPEEATNSFQSCIYQMVNSKHSIGMNSEGTAVSSY 700
[Close]
BLAST of DNA ligase vs. Ensembl Xenopus
Match: golga5 (golgin A5 [Source:Xenbase;Acc:XB-GENE-1014825])

HSP 1 Score: 708.368 bits (1827), Expect = 0.000e+0
Identity = 343/615 (55.77%), Postives = 449/615 (73.01%), Query Frame = 3 
Query:  561 ITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESK------LDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQ--IAEMYRNQDS--MKTGESAINPY 2375
            +T+TLSNF+RSVI L+P DLLPC+YLCLN++ P YEG ELG+GE ++  A+ QAT    + I S  +++GDLGL+A +  S+QR +  P KL    VF KLK I+  +G +S   KIDIIK L +A    E +YI RSL GKLRI LAEQ+VL+A+ QA+ LTPP            K  + D+ K  I+    I+K  FC+ PNYD +I  L ++GI +LP HC + PG+P+KPMLAHP+KG+ E+ +RFD + FTCEYKYDGERAQIH+  +     ++ I+SRNQENNT+KYPDI+  I +I +  SV+SCI+D+EAVAWD E K I PFQ L+TRK+KDV+  +IK+QVC+YAFD++Y N +SLV+  F +RR++LR++F E  G F+ AT +D+ NTDEISEFL+QSIKD CEGLM+KTL+ DATYEI+KRSHNWLKLKKDYL+ +GDT+DLVVIGA  G GKR   YG FLLA YD ESE +QTIC++GTGFTDEDL+  Y+ LK+ V   P S Y ++ +  PD WF+P  VWE+K ADLSISP H+AA+GLV+ EKGISLRFPRF+RIR+DKK E AT + Q  I +M  ++ S  M +  +A++ Y
Sbjct:    1 MTQTLSNFLRSVIALTPGDLLPCIYLCLNRLGPAYEGLELGIGETILMKAVAQATGRQLEKIKSEAQEKGDLGLVAESSRSNQRTMFTPPKLMASGVFSKLKDIARMTGNASMNKKIDIIKGLFVACRHSEARYIARSLGGKLRIGLAEQSVLSAIAQAVCLTPPGHDAPPTVMDAGKGMSTDARKSWIEDKAMILKQTFCELPNYDAIIPILLEHGIDDLPKHCRLTPGIPLKPMLAHPTKGIGEVLKRFDEAAFTCEYKYDGERAQIHILENG----EVHIYSRNQENNTTKYPDIISRIPKI-KKESVKSCILDTEAVAWDPEKKQIQPFQVLTTRKRKDVDASEIKVQVCVYAFDMLYLNGESLVKEPFAKRRQLLRDSFLETEGEFMFATYMDTSNTDEISEFLDQSIKDSCEGLMVKTLEQDATYEIAKRSHNWLKLKKDYLEGVGDTLDLVVIGAYLGKGKRTGIYGGFLLASYDEESEEYQTICKIGTGFTDEDLEKHYNYLKDHVIDSPRSYYRWDSATEPDHWFDPVQVWEVKCADLSISPVHKAALGLVEDEKGISLRFPRFLRIRDDKKPEEATNSFQSCIYQMVNSKHSIGMNSEGTAVSSY 610
[Close]
BLAST of DNA ligase vs. Ensembl Mouse
Match: Lig1 (ligase I, DNA, ATP-dependent [Source:MGI Symbol;Acc:MGI:101789])

HSP 1 Score: 736.487 bits (1900), Expect = 0.000e+0
Identity = 348/641 (54.29%), Postives = 462/641 (72.07%), Query Frame = 3 
Query:  426 PSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNES------KLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYR 2330
            P+ Y+P  N YH I DACWK  +K+P+LA+A+TFE IE  + RL++  TLSN +RSV+ LSP DLLP +YL LN++ P  +G ELGVG+ V+  A+ QAT    ++I + + ++GD+GL+A N  S+QR ++ P  LT+  VF K   I+  +G +S   K+DIIK L +A    E +YI RSL G+LR+ LAEQ+VLAAL QA++LTPP +          K +  ++ K  +++   I+K  FC+ P+ D +I  L ++G+  LP+HC + PGVP+KPMLAHP++GVSE+ +RF+  DFTCEYKYDG+RAQIHV        +++IFSRNQE+NT KYPDI+  I +I ++ SV S I+D+EAVAWDRE K I PFQ L+TRK+K+V+  +I++QVCLYAFDLIY N +SLV      RR++LRENF E  G FV  TSLD+ +T++I+EFLEQS+KD CEGLM+KTLD DATYEI+KRSHNWLKLKKDYLD +GDT+DLVVIGA  G GKRA +YG FLLA YD ESE  Q IC+LGTGF+DE+L+  +  L+  V   P      + +  PD W +P  VWE+K ADLS+SP + AA GLVDKEKGISLRFPRFIR+R+DK+ E ATT+ Q+A +YR
Sbjct:  277 PANYNPSKNNYHPIEDACWKHGQKVPFLAVARTFEKIEEVSARLKMVETLSNLLRSVVALSPPDLLPVLYLSLNRLGPPQQGLELGVGDGVLLKAVAQATGRQLESIRAEVAEKGDVGLVAENSRSTQRLMLPPPPLTISGVFTKFCDIARLTGSASMAKKMDIIKGLFVACRHSEARYIARSLSGRLRLGLAEQSVLAALAQAVSLTPPGQEFPTAVVDAGKGKTAEARKMWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGVPLKPMLAHPTRGVSEVLKRFEEVDFTCEYKYDGQRAQIHVLEGG----EVKIFSRNQEDNTGKYPDIISRIPKI-KHPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVRQPLSRRRQLLRENFVETEGEFVFTTSLDTKDTEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLAAYDEESEELQAICKLGTGFSDEELEEHHQSLQALVLPTPRPYVRIDGAVAPDHWLDPSIVWEVKCADLSLSPIYPAARGLVDKEKGISLRFPRFIRVRKDKQPEQATTSNQVASLYR 912
[Close]
BLAST of DNA ligase vs. Ensembl Mouse
Match: Lig1 (ligase I, DNA, ATP-dependent [Source:MGI Symbol;Acc:MGI:101789])

HSP 1 Score: 736.487 bits (1900), Expect = 0.000e+0
Identity = 348/641 (54.29%), Postives = 462/641 (72.07%), Query Frame = 3 
Query:  426 PSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNES------KLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYR 2330
            P+ Y+P  N YH I DACWK  +K+P+LA+A+TFE IE  + RL++  TLSN +RSV+ LSP DLLP +YL LN++ P  +G ELGVG+ V+  A+ QAT    ++I + + ++GD+GL+A N  S+QR ++ P  LT+  VF K   I+  +G +S   K+DIIK L +A    E +YI RSL G+LR+ LAEQ+VLAAL QA++LTPP +          K +  ++ K  +++   I+K  FC+ P+ D +I  L ++G+  LP+HC + PGVP+KPMLAHP++GVSE+ +RF+  DFTCEYKYDG+RAQIHV        +++IFSRNQE+NT KYPDI+  I +I ++ SV S I+D+EAVAWDRE K I PFQ L+TRK+K+V+  +I++QVCLYAFDLIY N +SLV      RR++LRENF E  G FV  TSLD+ +T++I+EFLEQS+KD CEGLM+KTLD DATYEI+KRSHNWLKLKKDYLD +GDT+DLVVIGA  G GKRA +YG FLLA YD ESE  Q IC+LGTGF+DE+L+  +  L+  V   P      + +  PD W +P  VWE+K ADLS+SP + AA GLVDKEKGISLRFPRFIR+R+DK+ E ATT+ Q+A +YR
Sbjct:  277 PANYNPSKNNYHPIEDACWKHGQKVPFLAVARTFEKIEEVSARLKMVETLSNLLRSVVALSPPDLLPVLYLSLNRLGPPQQGLELGVGDGVLLKAVAQATGRQLESIRAEVAEKGDVGLVAENSRSTQRLMLPPPPLTISGVFTKFCDIARLTGSASMAKKMDIIKGLFVACRHSEARYIARSLSGRLRLGLAEQSVLAALAQAVSLTPPGQEFPTAVVDAGKGKTAEARKMWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGVPLKPMLAHPTRGVSEVLKRFEEVDFTCEYKYDGQRAQIHVLEGG----EVKIFSRNQEDNTGKYPDIISRIPKI-KHPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVRQPLSRRRQLLRENFVETEGEFVFTTSLDTKDTEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLAAYDEESEELQAICKLGTGFSDEELEEHHQSLQALVLPTPRPYVRIDGAVAPDHWLDPSIVWEVKCADLSLSPIYPAARGLVDKEKGISLRFPRFIRVRKDKQPEQATTSNQVASLYR 912
[Close]
BLAST of DNA ligase vs. Ensembl Mouse
Match: Lig1 (ligase I, DNA, ATP-dependent [Source:MGI Symbol;Acc:MGI:101789])

HSP 1 Score: 736.487 bits (1900), Expect = 0.000e+0
Identity = 348/641 (54.29%), Postives = 462/641 (72.07%), Query Frame = 3 
Query:  426 PSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNES------KLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYR 2330
            P+ Y+P  N YH I DACWK  +K+P+LA+A+TFE IE  + RL++  TLSN +RSV+ LSP DLLP +YL LN++ P  +G ELGVG+ V+  A+ QAT    ++I + + ++GD+GL+A N  S+QR ++ P  LT+  VF K   I+  +G +S   K+DIIK L +A    E +YI RSL G+LR+ LAEQ+VLAAL QA++LTPP +          K +  ++ K  +++   I+K  FC+ P+ D +I  L ++G+  LP+HC + PGVP+KPMLAHP++GVSE+ +RF+  DFTCEYKYDG+RAQIHV        +++IFSRNQE+NT KYPDI+  I +I ++ SV S I+D+EAVAWDRE K I PFQ L+TRK+K+V+  +I++QVCLYAFDLIY N +SLV      RR++LRENF E  G FV  TSLD+ +T++I+EFLEQS+KD CEGLM+KTLD DATYEI+KRSHNWLKLKKDYLD +GDT+DLVVIGA  G GKRA +YG FLLA YD ESE  Q IC+LGTGF+DE+L+  +  L+  V   P      + +  PD W +P  VWE+K ADLS+SP + AA GLVDKEKGISLRFPRFIR+R+DK+ E ATT+ Q+A +YR
Sbjct:  277 PANYNPSKNNYHPIEDACWKHGQKVPFLAVARTFEKIEEVSARLKMVETLSNLLRSVVALSPPDLLPVLYLSLNRLGPPQQGLELGVGDGVLLKAVAQATGRQLESIRAEVAEKGDVGLVAENSRSTQRLMLPPPPLTISGVFTKFCDIARLTGSASMAKKMDIIKGLFVACRHSEARYIARSLSGRLRLGLAEQSVLAALAQAVSLTPPGQEFPTAVVDAGKGKTAEARKMWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGVPLKPMLAHPTRGVSEVLKRFEEVDFTCEYKYDGQRAQIHVLEGG----EVKIFSRNQEDNTGKYPDIISRIPKI-KHPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVRQPLSRRRQLLRENFVETEGEFVFTTSLDTKDTEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLAAYDEESEELQAICKLGTGFSDEELEEHHQSLQALVLPTPRPYVRIDGAVAPDHWLDPSIVWEVKCADLSLSPIYPAARGLVDKEKGISLRFPRFIRVRKDKQPEQATTSNQVASLYR 912
[Close]
BLAST of DNA ligase vs. Ensembl Mouse
Match: Lig3 (ligase III, DNA, ATP-dependent [Source:MGI Symbol;Acc:MGI:109152])

HSP 1 Score: 191.43 bits (485), Expect = 4.658e-50
Identity = 131/381 (34.38%), Postives = 190/381 (49.87%), Query Frame = 3 
Query: 1233 VPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENS--SVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDK--MGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKET-VTRKP--------VSSYDYEKSQIPDCWFEPK--YVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYR 2330
             P++PMLA   K +    ++  N  F+ E KYDGER Q+H   D         FSR+ +      P  V   K+ +  +    +S I+DSE +  D  T   LPF  L   KK    + +    VCL+ FD IYFND SL++    ERRK L +N  E     + +         ++++ + + I++  EGL++K  D   TYE  KR  +WLK+KKDYL++  M DT DLVV+GA YG G +      FL+ CYD +S+ + T+ +   G  D  L     EL    +++ P        ++   Y    +PD    PK   VWEI  A+ S S  H A         GIS+RFPR  RIR+DK  ++AT   Q+ E+Y+
Sbjct:  481 TPVQPMLAEACKSIEYAMKKCPNGMFS-EIKYDGERVQVHKKGD-----HFSYFSRSLK---PVLPHKVAHFKDYIPKAFPGGQSMILDSEVLLIDNNTGKPLPFGTLGVHKKAAFQDAN----VCLFVFDCIYFNDVSLMDRPLCERRKFLHDNMVEIRNRIMFSEMKQVTKASDLADMINRVIREGLEGLVLK--DVKGTYEPGKR--HWLKVKKDYLNEGAMADTADLVVLGAFYGQGSKGGMMSIFLMGCYDPDSQKWCTVTKCAGGHDDATLARLQKELVMVKISKDPSKIPSWLKINKIYYPDFIVPD----PKKAAVWEITGAEFSRSEAHTA--------DGISIRFPRCTRIRDDKDWKSATNLPQLKELYQ 832
[Close]
BLAST of DNA ligase vs. Ensembl Mouse
Match: Lig3 (ligase III, DNA, ATP-dependent [Source:MGI Symbol;Acc:MGI:109152])

HSP 1 Score: 191.43 bits (485), Expect = 6.707e-50
Identity = 131/381 (34.38%), Postives = 190/381 (49.87%), Query Frame = 3 
Query: 1233 VPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENS--SVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDK--MGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKET-VTRKP--------VSSYDYEKSQIPDCWFEPK--YVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYR 2330
             P++PMLA   K +    ++  N  F+ E KYDGER Q+H   D         FSR+ +      P  V   K+ +  +    +S I+DSE +  D  T   LPF  L   KK    + +    VCL+ FD IYFND SL++    ERRK L +N  E     + +         ++++ + + I++  EGL++K  D   TYE  KR  +WLK+KKDYL++  M DT DLVV+GA YG G +      FL+ CYD +S+ + T+ +   G  D  L     EL    +++ P        ++   Y    +PD    PK   VWEI  A+ S S  H A         GIS+RFPR  RIR+DK  ++AT   Q+ E+Y+
Sbjct:  481 TPVQPMLAEACKSIEYAMKKCPNGMFS-EIKYDGERVQVHKKGD-----HFSYFSRSLK---PVLPHKVAHFKDYIPKAFPGGQSMILDSEVLLIDNNTGKPLPFGTLGVHKKAAFQDAN----VCLFVFDCIYFNDVSLMDRPLCERRKFLHDNMVEIRNRIMFSEMKQVTKASDLADMINRVIREGLEGLVLK--DVKGTYEPGKR--HWLKVKKDYLNEGAMADTADLVVLGAFYGQGSKGGMMSIFLMGCYDPDSQKWCTVTKCAGGHDDATLARLQKELVMVKISKDPSKIPSWLKINKIYYPDFIVPD----PKKAAVWEITGAEFSRSEAHTA--------DGISIRFPRCTRIRDDKDWKSATNLPQLKELYQ 832
[Close]
BLAST of DNA ligase vs. UniProt/SwissProt
Match: sp|P51892|DNLI1_XENLA (DNA ligase 1 OS=Xenopus laevis OX=8355 GN=lig1 PE=2 SV=1)

HSP 1 Score: 759.985 bits (1961), Expect = 0.000e+0
Identity = 363/661 (54.92%), Postives = 481/661 (72.77%), Query Frame = 3 
Query:  429 SEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESK------LDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKTGESAINPYEDDEFY 2393
            +EY+P  + YH I+DACW   +K+PYLA+A+TFE IE  + RL+   TLSNF+RSVI L+P+DLLPC+YLCLN++ P YEG ELG+GE ++  A+ QAT    + I +  +++GDLGL+A +  S+QR +  P KL    VF KLK I+  +G +S   KIDIIK L +A    E +YI RSL GKLRI LAEQ+VL+++ QA+ LTPP            K  + D+ K  I++   I+K  FC+ PNYD +I  L ++GI +LP HC + PG+P+KPMLAHP+KG+ E+ +RFD + FTCEYKYDGERAQIH+    NG+  + ++SRNQENNT+KYPDI+  I +I +  SV+SCI+D+EAVA D E K I PFQ L+TRK+KDV+  +IK+QVC+YAFD++Y N +SLV+  F +RR++LR++F E  G F+ AT +D  NTDEISEFL+QSIKD CEGLM+KTL+ DATYEI+KRSHNWLKLKKDYL+ +GDT+DLVVIGA  G GKR   YG FLLA YD ESE +QTIC++GTGFTD+DL+  Y+ LK+ V   P S Y ++ +  PD WF+P  VWE+K ADLSISP H+AA+GLV+ +KGISLRFPRF+RIR+DKK E +T + Q+A++YR Q  ++   S     ED  FY
Sbjct:  417 TEYNPSKSKYHPIDDACWCNGQKVPYLAVARTFERIEEESARLKNVETLSNFLRSVIALTPEDLLPCIYLCLNRLGPAYEGLELGIGETILMKAVAQATGRQLEKIKAEAQEKGDLGLVAESSRSNQRTMFTPPKLMASGVFGKLKDIARMTGNASMNKKIDIIKGLFVACRHSEARYIARSLGGKLRIGLAEQSVLSSIAQAVCLTPPGRDAPPTVMDAGKGMSADARKSWIEEKAMILKQTFCELPNYDAIIPILLEHGIDDLPKHCRLTPGIPLKPMLAHPTKGIGEVLKRFDEAAFTCEYKYDGERAQIHILE--NGE--VHVYSRNQENNTTKYPDIISRIPKI-KKESVKSCILDTEAVAGDAEKKQIQPFQVLTTRKRKDVDASEIKVQVCVYAFDMLYLNGESLVKEPFAKRRQLLRDSFLETEGQFMFATYMDKSNTDEISEFLDQSIKDSCEGLMVKTLEQDATYEIAKRSHNWLKLKKDYLEGVGDTLDLVVIGAYLGKGKRTGIYGGFLLASYDEESEEYQTICKIGTGFTDDDLEKHYNFLKDHVIENPRSYYRWDSATEPDHWFDPVQVWEVKCADLSISPVHKAALGLVEDQKGISLRFPRFLRIRDDKKPEESTNSFQVADLYRKQQQIQNTSSTEKAEED--FY 1070
[Close]
BLAST of DNA ligase vs. UniProt/SwissProt
Match: sp|P18858|DNLI1_HUMAN (DNA ligase 1 OS=Homo sapiens OX=9606 GN=LIG1 PE=1 SV=1)

HSP 1 Score: 738.413 bits (1905), Expect = 0.000e+0
Identity = 350/660 (53.03%), Postives = 467/660 (70.76%), Query Frame = 3 
Query:  426 PSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNES------KLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKT--GESAINPYED 2381
            PS Y+P  N YH + DACWKP +K+PYLA+A+TFE IE  + RL +  TLSN +RSV+ LSP DLLP +YL LN + P  +G ELGVG+ V+  A+ QAT    +++ +   ++GD+GL+A N  S+QR ++ P  LT   VF K + I+  +G +S   KIDIIK L +A    E ++I RSL G+LR+ LAEQ+VLAAL QA++LTPP +          K +  ++ K  +++   I+K  FC+ P+ D +I  L ++G+  LP+HC + PG+P+KPMLAHP++G+SE+ +RF+ + FTCEYKYDG+RAQIH         +++IFSRNQE+NT KYPDI+  I +I +  SV S I+D+EAVAWDRE K I PFQ L+TRK+K+V+  +I++QVCLYAFDLIY N +SLV      RR++LRENF E  G FV ATSLD+ + ++I+EFLEQS+KD CEGLM+KTLD DATYEI+KRSHNWLKLKKDYLD +GDT+DLVVIGA  G GKRA +YG FLLA YD +SE  Q IC+LGTGF+DE+L+  +  LK  V   P      + + IPD W +P  VWE+K ADLS+SP + AA GLVD +KGISLRFPRFIR+REDK+ E ATT+ Q+A +YR Q  ++   GE + +  ED
Sbjct:  263 PSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGG----EVKIFSRNQEDNTGKYPDIISRIPKI-KLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQQGEDSGSDPED 917
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BLAST of DNA ligase vs. UniProt/SwissProt
Match: sp|P37913|DNLI1_MOUSE (DNA ligase 1 OS=Mus musculus OX=10090 GN=Lig1 PE=1 SV=2)

HSP 1 Score: 735.332 bits (1897), Expect = 0.000e+0
Identity = 348/641 (54.29%), Postives = 462/641 (72.07%), Query Frame = 3 
Query:  426 PSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNES------KLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYR 2330
            P+ Y+P  N YH I DACWK  +K+P+LA+A+TFE IE  + RL++  TLSN +RSV+ LSP DLLP +YL LN++ P  +G ELGVG+ V+  A+ QAT    ++I + + ++GD+GL+A N  S+QR ++ P  LT+  VF K   I+  +G +S   K+DIIK L +A    E +YI RSL G+LR+ LAEQ+VLAAL QA++LTPP +          K +  ++ K  +++   I+K  FC+ P+ D +I  L ++G+  LP+HC + PGVP+KPMLAHP++GVSE+ +RF+  DFTCEYKYDG+RAQIHV        +++IFSRNQE+NT KYPDI+  I +I ++ SV S I+D+EAVAWDRE K I PFQ L+TRK+K+V+  +I++QVCLYAFDLIY N +SLV      RR++LRENF E  G FV  TSLD+ +T++I+EFLEQS+KD CEGLM+KTLD DATYEI+KRSHNWLKLKKDYLD +GDT+DLVVIGA  G GKRA +YG FLLA YD ESE  Q IC+LGTGF+DE+L+  +  L+  V   P      + +  PD W +P  VWE+K ADLS+SP + AA GLVDKEKGISLRFPRFIR+R+DK+ E ATT+ Q+A +YR
Sbjct:  261 PANYNPSKNNYHPIEDACWKHGQKVPFLAVARTFEKIEEVSARLKMVETLSNLLRSVVALSPPDLLPVLYLSLNRLGPPQQGLELGVGDGVLLKAVAQATGRQLESIRAEVAEKGDVGLVAENSRSTQRLMLPPPPLTISGVFTKFCDIARLTGSASMAKKMDIIKGLFVACRHSEARYIARSLSGRLRLGLAEQSVLAALAQAVSLTPPGQEFPTVVVDAGKGKTAEARKMWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGVPLKPMLAHPTRGVSEVLKRFEEVDFTCEYKYDGQRAQIHVLEGG----EVKIFSRNQEDNTGKYPDIISRIPKI-KHPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVRQPLSRRRQLLRENFVETEGEFVFTTSLDTKDTEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLAAYDEESEELQAICKLGTGFSDEELEEHHQSLQALVLPTPRPYVRIDGAVAPDHWLDPSIVWEVKCADLSLSPIYPAARGLVDKEKGISLRFPRFIRVRKDKQPEQATTSNQVASLYR 896
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BLAST of DNA ligase vs. UniProt/SwissProt
Match: sp|Q9JHY8|DNLI1_RAT (DNA ligase 1 OS=Rattus norvegicus OX=10116 GN=Lig1 PE=1 SV=1)

HSP 1 Score: 710.294 bits (1832), Expect = 0.000e+0
Identity = 336/641 (52.42%), Postives = 457/641 (71.29%), Query Frame = 3 
Query:  426 PSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNES------KLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYR 2330
            P+ Y+P  + YH I DACWK  +K+P+LA+A+TFE IE  + RL++  TLSN +RSV+ LSP DLLP +YL LN++ P  +G ELGVG+ V+  A+ QAT    ++I + + ++GD+GL+A N  S+QR ++    LTV  VF K   I+  +G +S   K+DIIK L +A    E ++I RSL G+LR+ LAEQ+VLAAL QA +LTPP +          K +  ++ K  +++   I+K  FC+ P+ D +I  L ++G+ +LP+HC + PGVP+KPMLAHP++GV E+ +RF+  DFTCEYKY G+RAQIHV        +++IFSRNQE+N+ KYPDI+  I +I ++ SV S I+D+EAVAWDRE K I PFQ L+TRK+K+V+  +I++QVCLYAFDLIY N +SL       RR++LRENF E  G FV ATSLD+ + ++I+EFLEQS+KD CEGLM+KTLD DATYEI+KRSHNWLKLKKDYL+ +GDT+DLVVIGA  G GKR  +YG FLLA YD ESE    IC+LGTGF+DE+L+  +  ++  +   P      + +  P+ W +P  VWE+K ADL++SP +RAA G+VDKEKGISLRFPRFIR+REDK+ E ATT+ Q+A +YR
Sbjct:  263 PTNYNPSKSNYHPIEDACWKHGQKVPFLAVARTFEKIEEVSARLKMVETLSNLLRSVVALSPTDLLPVLYLSLNRLGPPQQGLELGVGDGVLLKAVAQATGRQLESIRAEVAEKGDVGLVAENSRSTQRLMLPSPPLTVSGVFTKFCDIARLTGSASMAKKMDIIKGLFVACRYSEARFIARSLSGRLRLGLAEQSVLAALAQAGSLTPPGQEFPTVVVDAGKGKTAEARKMWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLESLPEHCKLSPGVPLKPMLAHPTRGVREVLKRFEEVDFTCEYKYYGQRAQIHVLEGG----EVKIFSRNQEDNSGKYPDIISRIPKI-KHPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLARQPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLEGVGDTLDLVVIGAYLGRGKRPGRYGGFLLAAYDEESEELAAICKLGTGFSDEELEEHHQNMQALLLPTPRPYVRIDGAVAPNHWLDPSIVWEVKCADLTLSPIYRAARGMVDKEKGISLRFPRFIRVREDKQPEQATTSDQVASLYR 898
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BLAST of DNA ligase vs. UniProt/SwissProt
Match: sp|Q9W1H4|DNLI1_DROME (DNA ligase 1 OS=Drosophila melanogaster OX=7227 GN=DNAlig1 PE=1 SV=2)

HSP 1 Score: 689.493 bits (1778), Expect = 0.000e+0
Identity = 346/655 (52.82%), Postives = 457/655 (69.77%), Query Frame = 3 
Query:  435 YDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNE-SKLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKTGESAINPYE-DDEFY 2393
            YDP  + YH + +A WK  +  PYLALA+TF+VIE T  RL++  TLSNF  SV+ +SP+DL+P VYL +N++AP YEG ELGV E  +  A+ +AT  +   I S+ +  GDLG++A     SQR + QPA L V  VF+KL+ I+  SG+S    K+D++ N+ +A    E ++ +RSL+GKLRI +AEQ++L AL  AI L   N       S+  D  K  I   T ++KTA+CQCPNYD++I ++ KY I  L + C + PG+P++PMLA P+KGV E+F+RF     TCE+KYDGERAQIH     N K +I IFSRN ENNT+KYPD++     +L+   V+S IIDSE VAWD E K ILPFQ LSTRK+K+V+  +IK+QVC+Y FDL+Y N  +LV  +  ERRK+L E+F E  G +  AT+LD+ + DE+ +FLE+SIK  CEGLM+KTLD +ATYEI+KRS NWLKLKKDYL  +GD++DLVVIG   G G+R   YG FLLACYD+E+E +Q+IC++GTGFTDEDL      L + VT    S Y Y+ S  PD WFEP  VWE+K ADLS+SP HRAA+G+VD E+GISLRFPRFIRIR+DK +ENAT A Q+A MY++QD +K  + +    E +DEFY
Sbjct:  104 YDPSADSYHPLKNAYWKDKKVTPYLALARTFQVIEETKGRLKMIDTLSNFFCSVMLVSPEDLVPSVYLSINQLAPAYEGLELGVAETTLMKAICKATGRNLAHIKSQTQLTGDLGIVAEQSRVSQRMMFQPAPLNVRDVFRKLREIAKLSGQS----KMDLVYNMFVACRSSEARFFIRSLIGKLRIGIAEQSLLTAL--AIGLVKKNHIDDCKASKVPDVYKDEIVDTTLLLKTAYCQCPNYDIIIPAILKYDIKELQERCPMHPGMPLRPMLAQPTKGVHEVFERFGGMQITCEWKYDGERAQIH----RNEKGEISIFSRNSENNTAKYPDLIARSTALLKGD-VKSYIIDSEIVAWDVERKQILPFQVLSTRKRKNVDIEEIKVQVCVYIFDLLYINGTALVTKNLSERRKLLLEHFQEVEGEWKFATALDTNDIDEVQQFLEESIKGNCEGLMVKTLDEEATYEIAKRSRNWLKLKKDYLSNVGDSLDLVVIGGYKGKGRRTGTYGGFLLACYDTENEEYQSICKIGTGFTDEDLQTHSEFLGKHVTSAAKSYYRYDPSLEPDHWFEPVQVWEVKCADLSLSPIHRAAIGIVDGERGISLRFPRFIRIRDDKNSENATDANQVAHMYQSQDQVKNNQKSSTQMEMEDEFY 747
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BLAST of DNA ligase vs. TrEMBL
Match: A0A098LZ92 (DNA ligase OS=Hypsiglena sp. JMG-2014 OX=1550645 PE=3 SV=1)

HSP 1 Score: 783.867 bits (2023), Expect = 0.000e+0
Identity = 370/662 (55.89%), Postives = 491/662 (74.17%), Query Frame = 3 
Query:  426 PSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNES----KLD--KSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKTGESAINPYEDDEFY 2393
            P+EY+P  + YH +NDACW P +KIPY+A+A+TFE IE  + RL+I  TLSN  RS I LSP+DLLPCVYLCLN++ P YEG ELG+G+ ++  AL QAT      I +   ++GDLGL+A N  ++Q  +  P KL   +VF KL+ I   +G SS   KIDIIK+L +A    E +Y+ RSL GKLRI LAEQ+VL+AL QA +LTPP +      LD  K ++ D+ K  +D+   I+K AFC+ PNYD+L+  L  +G+ +LP +C I PG+P+KPMLAHP+KG+ E+ +RF+ + FTCEYKYDGERAQIH+    NG+  + I+SRNQENNT+KYPDIV  I ++ +NS+V+SCI+D+EAVAWD  +K ILPFQ L+TRK+KDV+  +I++QVC+YAFD++Y N  SLV+    +RR +L  +FTE  G F+ ATS+D+ N DEI+EFLE+SIKD CEGLM+KTL+ DATYEI+KRSHNWLKLKKDYL+ +GDT+DLVVIGA  G GKRA  YG FLLACYD ESE FQ+IC++GTGF+DEDL+  ++ LK+ V  +P   Y +  +  PD W E ++VWE+K ADLSISP HRAA GLVD+EKGISLRFPRF+RIR+DKK E AT++ ++AE+YR Q  +   ++ ++  +DDEFY
Sbjct:  257 PAEYNPTKSSYHPVNDACWGPGQKIPYMAVARTFEYIEQESARLKIIETLSNLFRSAIVLSPQDLLPCVYLCLNQLGPAYEGLELGIGKTILMKALAQATGRQLDQIKAEAAEKGDLGLVAENSRTTQGTVFAPPKLGAAAVFGKLQAIGHMAGSSSMNKKIDIIKSLFVACRHSEARYVARSLEGKLRIGLAEQSVLSALAQAASLTPPGQKFPPDVLDAAKGKSADARKAWLDERALIVKQAFCELPNYDILVPVLLDHGVESLPQYCKITPGIPLKPMLAHPTKGIGEVLKRFEEAAFTCEYKYDGERAQIHILE--NGE--VHIYSRNQENNTTKYPDIVTRIPKV-KNSTVKSCILDAEAVAWDPVSKQILPFQVLTTRKRKDVDAAEIRVQVCIYAFDMLYLNGMSLVQKPLSQRRTLLHNSFTEVEGQFLFATSMDTSNVDEIAEFLERSIKDSCEGLMVKTLEVDATYEIAKRSHNWLKLKKDYLEGVGDTLDLVVIGAYLGKGKRAGTYGGFLLACYDEESEEFQSICKIGTGFSDEDLEKIHNSLKDYVIPQPRRYYRWGGTAEPDHWLESQHVWEVKCADLSISPIHRAASGLVDEEKGISLRFPRFLRIRDDKKPEEATSSAEVAELYRKQQQI---QNQLSLEKDDEFY 910
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BLAST of DNA ligase vs. TrEMBL
Match: H9GHC9 (DNA ligase OS=Anolis carolinensis OX=28377 GN=LIG1 PE=3 SV=2)

HSP 1 Score: 781.941 bits (2018), Expect = 0.000e+0
Identity = 371/662 (56.04%), Postives = 487/662 (73.56%), Query Frame = 3 
Query:  426 PSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNES------KLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKTGESAINPYEDDEFY 2393
            PSEY+   + YH I+DACW   +++PYLA+A+TFE IE  + RL+I  TLSNF RSVI LSP+DLLPCVYLCLN++ P YEG ELG+G+ ++  AL QAT      I +   ++GDLGL+A +  ++Q  +  P KL   +VF KL+ I    G SS   KIDIIK+L +A    E +YI RSL GKLRI LAEQ+VL+AL QA +LTPP +          K ++ ++ K  +D+   I+K AFC+ PNYD+++  L ++G+ +LP HC I PG+P+KPMLAHP+KG+ E+ +RF+ + FTCEYKYDGERAQIH+  +     ++ I+SRNQENNT+KYPDIV  I ++ + S+VESCI+D+EAVAWD ++K I PFQ L+TRK+KDV+  DI++QVC+YAFD++Y N QSLV     +RR +LR++FTE  G F+ ATS+D+ NTDEI+EFLE+SIKD CEGLM+KTL+ DATYEI+KRSHNWLKLKKDYLD +GDT+DLVVIGA  G GKRA  YG FLLACYD ESE FQ+IC++GTGFTDEDL+  ++ LK  V  +P   Y +  +  PD W E  +VWE+K ADLSISP HRAA GLVD+EKGISLRFPRF+R+R+DKK E ATT+ Q+AE+YR Q  ++  +S  N   +D+FY
Sbjct:  259 PSEYNSAKSNYHPIHDACWGSGQRVPYLAVARTFEWIEQESARLKIIETLSNFFRSVIALSPEDLLPCVYLCLNRLGPAYEGLELGIGKTILMKALAQATGRQLDQIKAEAAEKGDLGLVAESSRTTQGTMFAPPKLGAGAVFGKLQAIGRMMGSSSMNKKIDIIKSLFVACRHSEARYIARSLEGKLRIGLAEQSVLSALAQAASLTPPGQKFPPEILDASKGKSAETRKSWLDERALIVKQAFCELPNYDIIVPVLLEHGVESLPKHCKITPGIPLKPMLAHPTKGIGEVLKRFEEAAFTCEYKYDGERAQIHILENG----EVHIYSRNQENNTTKYPDIVSRIPKV-KKSTVESCILDAEAVAWDPDSKQIQPFQVLTTRKRKDVDTEDIRVQVCVYAFDMLYLNGQSLVREPLTQRRTLLRDSFTEVEGQFLFATSMDTSNTDEIAEFLERSIKDSCEGLMVKTLEVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGKGKRAGIYGGFLLACYDDESEEFQSICKIGTGFTDEDLEKLHTSLKAHVIPQPRPYYRWGGTAEPDHWLETHHVWEVKCADLSISPVHRAAAGLVDEEKGISLRFPRFLRLRDDKKPEEATTSAQVAELYRKQQQIQNQQSVEN--GNDDFY 913
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BLAST of DNA ligase vs. TrEMBL
Match: A0A402FQ34 (DNA ligase OS=Paroedura picta OX=143630 GN=parPi_0021613 PE=3 SV=1)

HSP 1 Score: 778.474 bits (2009), Expect = 0.000e+0
Identity = 370/664 (55.72%), Postives = 488/664 (73.49%), Query Frame = 3 
Query:  426 PSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNE----SKLD--KSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKTGESAINPYE--DDEFY 2393
            P++Y+P  N YH ++DACW P +++PYLA+A+TFE IE  + RL+I  TLSN  RSVI LSP+DLLPCVYLCLN++ P YEG ELG+G+ ++  AL QAT      I +   ++GDLGL+A N  ++Q  +  P KL    VF KL+ I   +G SS   KIDIIK+L +A    E +Y+ RSL GKLRI LAEQ+VL+AL QA +LTPP +      LD  K ++ ++ K  +D+   I+K AFC+ PNY+ ++  L ++G+ +LP HC I PG+P+KPMLAHP+KG+ E+ +RF+ + FTCEYKYDGERAQIH+    NG+  + I+SRNQENNTSKYPDIV  I ++ + S+V+SCI+D+EAVAWD ++K I PFQ L+TRK+KDV+  +I++QVC+YAFD++Y N QSLV  +  +RR +L ++FTE  G F+ ATS+D+ NTDEI++FLE SIKD CEGLM+KTL+ DATYEI+KRSHNWLKLKKDYLD +GDT+DLVVIGA  G GKRA  YG +LLACYD ESE FQ+IC++GTGFTDEDL+  ++ LK+ V  +P   Y +  +  PD W E ++VWE+K ADLSISP H+AA GLVD+EKGISLRFPRF+RIREDKK E AT + Q+AE+YR Q  +        P E  DD+FY
Sbjct:  270 PADYNPTKNNYHPVHDACWSPGQRVPYLAVARTFEQIEEMSARLKIIETLSNLFRSVIALSPEDLLPCVYLCLNRLGPAYEGLELGIGKTILMKALAQATGRQLDQIKAEAAEKGDLGLVAENSRTTQGTMFAPPKLGAAVVFGKLQAIGRMTGSSSMNKKIDIIKSLFVACRYSEARYVARSLEGKLRIGLAEQSVLSALAQAASLTPPGQKFPPEILDAAKGKSAEARKAWLDERALIVKQAFCELPNYNTIVPVLLEHGVESLPQHCKITPGIPLKPMLAHPTKGIGEVLKRFEEAAFTCEYKYDGERAQIHILE--NGE--VHIYSRNQENNTSKYPDIVSRISKV-KKSTVQSCILDAEAVAWDPDSKQIQPFQVLTTRKRKDVDATEIRVQVCVYAFDMLYLNGQSLVREALAQRRTLLHDSFTEVEGQFLFATSMDTNNTDEIADFLECSIKDSCEGLMVKTLEVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGKGKRAGIYGGYLLACYDEESEEFQSICKIGTGFTDEDLEKLHASLKDHVIPQPRPYYRWGGTAEPDHWLEAQHVWEVKCADLSISPVHKAATGLVDEEKGISLRFPRFLRIREDKKPEEATASSQVAELYRKQQQI----QNQQPVEKGDDDFY 924
[Close]
BLAST of DNA ligase vs. TrEMBL
Match: A0A210PFJ6 (DNA ligase OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT05982 PE=3 SV=1)

HSP 1 Score: 777.319 bits (2006), Expect = 0.000e+0
Identity = 373/666 (56.01%), Postives = 490/666 (73.57%), Query Frame = 3 
Query:  429 SEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQAT--DVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNES------KLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKTGESAINPY---EDDEFY 2393
            S Y P  + YH I+DACWKP EK+PYLALAKTFE IE  + RL+I   L NF RSVI LSP DLL CVYLCLNK+AP YEG ELG+GE V+  A+ Q+T   +DK  +D++ K  GDLG++A +  S+QR +  P KLT+ +VF KLK I+  SG +  + KIDIIK L +A  + E +Y++RSL GKLRI LAEQ+VL ALG A+ LTPP +          K  + ++LK  ++++   IK+ +C+CPNY  +I +L K GI +LP HC + PG+P+KPMLAHP+KGV E+ +RF+N++FTCEYKYDGERAQIH+  +      + I+SRN ENNT+KYPDI+  + +++++S V+SC+IDSEAVAWD E K I PFQ LS RK+KD +  +IKIQVC+YAFDL+Y N +SLV+  F+ RR++L E+F E  G FV A S+ S +T+EI+ FL++S+K  CEGLM+KTLD DATYEI+KRSHNWLKLKKDYL+ +GDT+DLVVIG   G+GKR  KYG FLLACY+ ESE FQ+IC++GTGF D+DL+   +  KE +  KP   Y ++ S  PD WFEP  VWE+K ADLSISP HRAA G+VD EKGISLRFPRF+RIR+DKK E+AT+A Q+A+MY+NQD ++  +S   P    +++EFY
Sbjct:  424 STYHPSKSRYHPIDDACWKPKEKVPYLALAKTFEAIEEISARLKIVDILCNFFRSVIALSPDDLLFCVYLCLNKLAPAYEGVELGIGETVLMKAIAQSTGRSMDKIKLDAQEK--GDLGIVAESSRSNQRTMFAPPKLTIRAVFTKLKEIALMSGNNVMSKKIDIIKGLFVACRQSEARYLIRSLGGKLRIGLAEQSVLTALGNAVFLTPPGQDFPPEILDAGKGLSAENLKKKMEESALTIKSVYCECPNYGSIISTLMKKGIEDLPKHCKLTPGIPLKPMLAHPTKGVGEVLKRFENAEFTCEYKYDGERAQIHILENGT----VNIYSRNSENNTTKYPDIIARVPKVMKDS-VKSCVIDSEAVAWDAEKKQIQPFQVLSHRKRKDADASEIKIQVCVYAFDLLYLNGESLVKEPFKRRRELLHESFEEVEGEFVFAKSMISSDTEEIAVFLDESVKGNCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLEGVGDTLDLVVIGGYLGSGKRTGKYGGFLLACYEPESEEFQSICKIGTGFKDDDLEQHATFFKEQLIDKPKQYYCWDSSHEPDHWFEPVQVWEVKCADLSISPTHRAASGIVDPEKGISLRFPRFLRIRDDKKPEDATSASQVADMYKNQDQIQNQQSTSGPSKEGDEEEFY 1082
[Close]
BLAST of DNA ligase vs. TrEMBL
Match: A0A2B4RKL2 (DNA ligase OS=Stylophora pistillata OX=50429 GN=lig1 PE=3 SV=1)

HSP 1 Score: 776.548 bits (2004), Expect = 0.000e+0
Identity = 379/683 (55.49%), Postives = 495/683 (72.47%), Query Frame = 3 
Query:  369 KTDDLNQTEIETVEKVNKIPSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNES----KLDKSQNF--DSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKTGESAINPYED--DEFY 2393
            KT   N+T +  + K    P+EY P  + YH I +ACW+  E++PYLA+AKTF  IE T+ RL+IT  LSNF RSVI LSP+DLLPCVYLCLNK+AP YEG ELG+GE ++  A+ ++T    + I   + ++GDLG++A +  S+QR +  P KLT  SVF KLK I+  +G SS T K + IK + +A    E +Y++RSL GKLRI LAEQ+VL ALG A+ LTPP++      +D ++NF  D LK   D+   I+KT +C+ P+Y+ LI SL ++G+  LP+HC + PG+P+KPMLAHPSKGV E+F+RF+++ FTCEYKYDGERAQIHV        +I I+SRNQE+NTSKYPDI++ + ++L    V+SCIID+EAVAWDRE K ILPFQ LSTRK+KD N  DIK+QVC+YAFDL+Y N +S ++ +F++RR+ LR +  E  G F+ A S DS N D+I+EFL+ SIK  CEGLM+KTLD DATYEI+KRSHNWLKLKKDYL+ +GDT+D+VVIG   G GKR   YG +LLACYD E+E FQTIC++GTGFTDE LD  Y   K+ V   P + Y Y+ +  PD WF P  VWEI+AADLS+SP H+AA+GLVD  KGISLRFPRF+RIR+DKK E AT + Q+AEMYR+Q+++K   +   P  D  D+FY
Sbjct:  364 KTSSSNKTGLSELVK----PTEYSPEKSDYHPIQNACWRHGERVPYLAVAKTFHAIEDTSARLKITSILSNFFRSVIVLSPEDLLPCVYLCLNKLAPAYEGIELGIGENILMKAVAESTGRSLQQIKYDVGEKGDLGIVAESCRSTQRTMFAPPKLTASSVFTKLKEIAMMTGHSSMTRKSEKIKGMFVACRDAEARYLIRSLGGKLRIGLAEQSVLTALGHAVFLTPPSKEFPSPIIDNAKNFSGDGLKKKQDEAALIVKTCYCEMPSYNKLIPSLLEHGLETLPEHCHLTPGIPLKPMLAHPSKGVEEVFKRFEDAAFTCEYKYDGERAQIHVLESG----EIHIYSRNQEDNTSKYPDIIERMPKVL-GDKVKSCIIDAEAVAWDREKKQILPFQILSTRKRKDANASDIKVQVCVYAFDLLYLNGKSYIKETFQKRREALRSSLVEVEGEFMFAQSSDSINADDIAEFLDNSIKGNCEGLMVKTLDMDATYEIAKRSHNWLKLKKDYLNGVGDTLDVVVIGGYLGKGKRTGSYGGYLLACYDPENEEFQTICKIGTGFTDELLDKHYQFFKDQVIPHPKAYYRYDDNLAPDHWFVPVQVWEIRAADLSVSPVHKAALGLVDPVKGISLRFPRFLRIRDDKKPEQATDSSQVAEMYRSQETVKNNANP-PPTTDASDDFY 1036
[Close]
BLAST of DNA ligase vs. Ensembl Cavefish
Match: lig1 (ligase I, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB-GENE-110404-2])

HSP 1 Score: 699.508 bits (1804), Expect = 0.000e+0
Identity = 344/619 (55.57%), Postives = 439/619 (70.92%), Query Frame = 3 
Query:  552 RLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNE----SKLD--KSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKTGESAINPYEDDEF 2390
            RL    TLSN +RSVI LSP DLL CVYLCLN++ P Y+G ELGVGE V+  A+ QAT      I +  +++GDLGL+A +  S+QR +  PA L    VF KLK I   SG S+   KIDIIK L +A    E ++IVRSL GKLRI LAEQ+VLAAL QA+ LTPP +    S +D  K  + +S +  +++   I+K  +C+ PNYD++I  L K GI  LP HC + PGVP++PMLAHP+KGV E+ +RFD + FTCEYKYDGERAQIH+  +     +++IFSRNQE+NTSKYPDI+  I ++ +  SV  C++D+EAVAWDRE K I PFQ L+TRK+KDV+  +IK+QVC+YAFDL+Y N +SLV      RR +L+E+F EK G FV A SLDS NTD I+EFLEQS++D CEGLM+KTL+ DATYEI+KRSHNWLKLKKDYL+ +GDT+DL VIGA  G GKRA  YG FLLACYD E+E FQ++C++GTGF DEDL+  Y+ LKE +  KP   Y  ++S  PD W +   VWE+K ADLS+SP ++AA+GLVD EKGISLRFPRF+ IREDKK E+ATT  Q+    +N     TG +  N  +   F
Sbjct:    3 RLRNIETLSNLLRSVILLSPDDLLCCVYLCLNQLGPAYQGLELGVGETVLMKAVAQATGRQLDKIKAEAQEKGDLGLVAESSRSNQRMMFAPASLNAAGVFNKLKEIGNMSGNSAMNKKIDIIKGLFVACRFSEARFIVRSLAGKLRIGLAEQSVLAALSQAVCLTPPGQEFPPSVIDAGKGMSTESRRAWLEEKALILKQTYCEMPNYDVIIPVLVKEGIDQLPKHCKLTPGVPLRPMLAHPTKGVGEVMKRFDEAAFTCEYKYDGERAQIHILENG----EVRIFSRNQEDNTSKYPDIISRIPQV-KKESVRCCVLDTEAVAWDREKKQIQPFQVLTTRKRKDVDASEIKVQVCVYAFDLLYLNGESLVREPLSRRRALLKESFVEKEGEFVFARSLDSDNTDTIAEFLEQSVRDSCEGLMVKTLEKDATYEIAKRSHNWLKLKKDYLEGVGDTMDLCVIGAYLGKGKRAGSYGGFLLACYDEENEEFQSVCKIGTGFKDEDLEQHYNFLKEHILPKPRPYYRVDQSAEPDVWLDAVQVWEVKCADLSLSPVYKAAMGLVDSEKGISLRFPRFLHIREDKKPEDATTGAQVTSTPQN-----TGHTVHNTPQRQSF 611
[Close]
BLAST of DNA ligase vs. Ensembl Cavefish
Match: lig3 (DNA ligase 3 [Source:NCBI gene;Acc:103047681])

HSP 1 Score: 172.17 bits (435), Expect = 9.324e-44
Identity = 128/385 (33.25%), Postives = 188/385 (48.83%), Query Frame = 3 
Query: 1233 VPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENS--SVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDK--MGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFE------PKY---------VWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYR 2330
             P++PMLA   K +    ++  N  ++ E KYDGER Q+H + D         FSR+ +      P  V   KE +  +     S I+D+E +  D +T   LPF  L   KK    +     QV L+ FD IYFN  SL++    ERRK L +N  E P   + +         +++E + + I++  EGL++K  D    YE  KR  +WLK+KKDYL++  M DT DLVV+G  +G+G +     +FL+ CYD +S+ + T+ +   G+ D  L     EL        V     + S+IP  W +      P +         VWEI  A+ S S  H A         GIS+RFPR  R+R+DK  + AT   Q+ E+YR
Sbjct:  479 TPVQPMLAEACKSIEHAMKKCPNGMYS-EIKYDGERVQVHKNGD-----HFSYFSRSLK---PVLPHKVAHFKEFIPQAFAGGHSMILDAEVLLIDTKTSKPLPFGTLGVHKKAAFQDA----QVGLFVFDCIYFNGVSLMDKPLCERRKFLHDNMIEVPNRILFSEMKHVTRAADLAEMITRVIREGLEGLVLK--DIKGLYEPGKR--HWLKVKKDYLNEGAMADTADLVVLGGFFGSGSKGGIMSSFLMGCYDPDSKKWCTVTKCSGGYDDATLARLQKELD-------VIKIGKDPSKIPG-WLKIVKNYYPDFLIRDPQKAPVWEITGAEFSKSEMHTA--------DGISIRFPRCTRMRDDKDWKTATNLPQLKELYR 830
[Close]
BLAST of DNA ligase vs. Ensembl Cavefish
Match: lig4 (ligase IV, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB-GENE-070820-10])

HSP 1 Score: 143.28 bits (360), Expect = 1.208e-34
Identity = 127/488 (26.02%), Postives = 228/488 (46.72%), Query Frame = 3 
Query:  924 NLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESKLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEV--DIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESE-----LFQTICRLGTGFTDEDLDNFYSELKET--VTRK--PVSSYDYEKSQIPDCWFEPK--YVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMK 2348
            +L+  SS  E+K+++R +L  +++ ++++TVL           P+ ++L                       +    + D +   L    +S   +  SI      KPMLA  +  + +I ++  +  F  E K DGER Q+H   D         F   Q+   S     +      +    V +CI+D E +A++   ++ +  QK S   K D+  +  D  +Q C   FD++  NDQ       ++R   L+  FT   G   L    +  N  ++   L ++I ++ EG+M+K  D  + Y+  KR   WLK+K +Y+D + D +DL+++G  +G G+R+     FL A  +S S      +F TICR+G+G+T ++L +   +L +   V RK  P +S     ++ P+ + EP+   + ++KAA++  S  ++            +LRFPR  RIREDK+     T  ++++ +R + S K
Sbjct:  233 HLITQSSALEQKWLIRMILKDMKLGVSKETVLQVFH-------PDAAEL-----------------------YNVTTDLDKVCRQLHDPSVS--LNEVSIGLFSAFKPMLAAVA-NIRQIEKQMKDQPFYIETKLDGERIQLHKDGDVYKYYTRNSFEYTQQFGASPLEGSLTPYIHNVFKPHVVNCILDGEMMAYNPTAETFM--QKGS---KFDIKRLMDDSDLQTCFCVFDVLLVNDQKFGNEPLKKRYDTLQTVFTPIKGRIQLVPKAEGRNMQQVVNALNEAIDNREEGIMVK--DPMSIYKPDKRGDGWLKIKPEYVDGLMDELDLLIVGGYWGKGRRSGMLSHFLCAVAESPSPGEKPTVFHTICRIGSGYTMKELYDLGLKLAKHWKVYRKNDPPASI-LCGTEKPEVYIEPQNSVIIQVKAAEIVESDMYKT---------NCTLRFPRIERIREDKEWHQCMTLDELSQ-FRTKASGK 669
[Close]
BLAST of DNA ligase vs. Ensembl Sea Lamprey
Match: lig1 (ligase I, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB-GENE-110404-2])

HSP 1 Score: 414.075 bits (1063), Expect = 4.677e-133
Identity = 196/384 (51.04%), Postives = 270/384 (70.31%), Query Frame = 3 
Query:  435 YDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNES----KLD--KSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKK 1568
            Y+P  + YH INDACW+  +++PYLA+A+TFE IE  + RL+I  TLSNF+RSVI L+P DLLPC+YLCLN++ P Y G ELG+GE ++  A+ QAT      I +  +++GDLG++A    S+QR +  P KL   +VF KLK IS  +G +S   KID++K + +A    E +Y++RSL GKLRI LAEQ+V+AAL QA++LTPP +      LD  K  + DS K  I++   I+K  +C+ PNYD+++ +L K G+ NLP  C + PGVP+KPMLAHP+KG+ E+ +RFD + FTCEYKYDGERAQIH+  + +    + I+SRNQENNT+KYPDI+    ++ +   V SC+IDSEAVAWD+E K I PFQ L+TRK+K
Sbjct:  408 YNPAKSHYHPINDACWEHEQRVPYLAVARTFEKIEEESARLKIVETLSNFLRSVIALTPDDLLPCIYLCLNQLGPAYLGQELGIGETILMKAVAQATGRQLDKIKAEAQEKGDLGIVAECSRSTQRTMFTPPKLNATTVFSKLKDISRLTGNTSMNKKIDVVKTMFVACRHSEARYLIRSLGGKLRIGLAEQSVIAALAQAVSLTPPGQEFPPKVLDGGKGMSPDSRKAWIEEKNQILKQTYCELPNYDVIVSTLLKEGLDNLPKFCKLTPGVPMKPMLAHPTKGIGEVLKRFDEAAFTCEYKYDGERAQIHLLENGD----LHIYSRNQENNTTKYPDIISRFSKV-KKEHVRSCVIDSEAVAWDQEKKQIQPFQVLTTRKRK 786
[Close]
BLAST of DNA ligase vs. Ensembl Sea Lamprey
Match: lig3 (ligase III, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB-GENE-030131-8453])

HSP 1 Score: 162.155 bits (409), Expect = 1.177e-41
Identity = 104/308 (33.77%), Postives = 156/308 (50.65%), Query Frame = 3 
Query: 1236 PIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENS--SVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDK--MGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFE 2147
            P++PMLA   K V+   ++  N  +  E KYDGER Q+H + D+      Q FSR+ +      P  V   ++ +  +     S I+D+E +  D  T   LPF  L   KK    + +    VCL+ FD IYFN +SL++ S ++RRK L +N  E P   + +         +++E + + IK+  EGL++K  D    YE  KR  +WLK+KKDYL++  M DT DL V+GA YG G        FL+ CYD  S  + T+ +  +G+ D  L+    EL+     K         S+IPD W +
Sbjct:  439 PVQPMLAEACKSVAYAMKKCPNGMYA-EIKYDGERVQVHKNGDS-----FQYFSRSLK---PVLPHKVAHFRDYIPKAFPGGTSMILDAEVLLIDTSTSKPLPFGTLGVHKKAAFQDAN----VCLFVFDCIYFNGESLMDRSIKDRRKFLHDNMVEIPNHILFSEMKHVTRASDLAEMISRVIKEGLEGLVLK--DVLGIYEPGKR--HWLKVKKDYLNQGAMADTADLAVLGAYYGHGSNGGIMSIFLMGCYDENSGRWCTVTKCSSGYDDATLNRLQKELEMVKISK-------SASKIPD-WLK 721
[Close]
BLAST of DNA ligase vs. Ensembl Sea Lamprey
Match: lig4 (ligase IV, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB-GENE-070820-10])

HSP 1 Score: 117.472 bits (293), Expect = 1.502e-27
Identity = 86/328 (26.22%), Postives = 151/328 (46.04%), Query Frame = 3 
Query: 1383 IQIFSRNQENNTSKY---PDIVKLIKEILEN--SSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEV----DIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESE-----LFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYE-----KSQIPDCWFEP--KYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATT 2303
             + FSRN    T+++   P    L + +       V S I+D E + ++  + + +     +   + DV  +    D  +Q C   FD++  N Q L     R R ++LRE F    G        +     ++++ L  +I  + EG+MIK  D  + Y+  KR + W K+K +Y+  + D +DL+++G  +G G+R      FL A  +   +     +F T+CR+G+G+T ++L +    LK     +P    D        ++ P+ + EP    V +++AA++  S  +R          G +LRFPR  RIR+DK      T
Sbjct:    1 FRYFSRNGFEYTAQFGGAPTEGSLTRFVHAAFAPHVSSVILDGEMMGYNARSSTFV-----TKGGRFDVKHLGADADSPLQACFCVFDVLLLNGQRLTGEPLRRRDELLRETFAPVEGRLRAVEKREIRTRGDVADALNDAIDSREEGIMIK--DPASVYKPDKRGYGWYKIKPEYMGDLMDELDLLIVGGYWGKGRRGGMMSHFLCAVAEVAEDGERPAVFHTLCRVGSGYTMQELYDL--GLKLAPHWRPYRRKDPPGCILCATEKPEVYLEPCNAVVVQVRAAEIVASDQYRT---------GCTLRFPRIERIRDDKAWHECLT 310
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BLAST of DNA ligase vs. Ensembl Yeast
Match: CDC9 (DNA ligase I found in nucleus and mitochondria; essential enzyme that joins Okazaki fragments during DNA replication; also acts in ribonucleotide excision repair, base excision repair, and recombination; DNA ligase I mutants trigger ubiquitination of PCNA at K107, facilitating Rad59p-mediated bypass of unligated Okazaki fragments; human homolog LIG1 can complement yeast cdc9 temperature-sensitive mutant at restrictive temperature [Source:SGD;Acc:S000002323])

HSP 1 Score: 527.709 bits (1358), Expect = 1.392e-177
Identity = 274/620 (44.19%), Postives = 391/620 (63.06%), Query Frame = 3 
Query:  498 IPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQAT-DVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPN-ESKLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDN-DATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMK 2348
            IPY  + + F  IE+ + RLEI R  S+F   ++  S K+L+P  YL +N++ PDYE          +    I  T       I  + K  GDLG IA    + Q  + +P  LTV  VF+ L+ I+ T GK S   K+ +IK +L A    E K+++RSL  KLRI LAE+TVL +L +A+ L   N E   DK    D L+    K    I+ AFCQ PNY+++I S  ++GI NL  +C++ PG+P+KPMLA P+K ++E+  RF    FT EYKYDGERAQ+H+  D      ++I+SRN EN T +YP+I  +   I +  + ++ I+D EAVAWD++   ILPFQ LSTRK+KDV   D+K++VCL+AFD++ +ND+ L+  S +ERR+ L +     PG F  AT + + N DE+ +FL++S+   CEGLM+K L+  ++ YE SKRS NWLKLKKDYL+ +GD++DL V+GA YG GKR   YG FLL CY+ ++  F+T C++GTGF+DE L   +  L  T+   P +++ ++ S  PD WFEP  ++E+  ADLS+SP ++A     D  KG+SLRFPRF+RIREDK  E+AT++ QI E+Y NQ  M+
Sbjct:  146 IPYSEVCEVFNKIEAISSRLEIIRICSDFFIKIMKQSSKNLIPTTYLFINRLGPDYEAGLELGLGENLLMKTISETCGKSMSQIKLKYKDIGDLGEIAMGARNVQPTMFKPKPLTVGEVFKNLRAIAKTQGKDSQLKKMKLIKRMLTACKGIEAKFLIRSLESKLRIGLAEKTVLISLSKALLLHDENREDSPDKDVPMDVLESAQQK----IRDAFCQVPNYEIVINSCLEHGIMNLDKYCTLRPGIPLKPMLAKPTKAINEVLDRFQGETFTSEYKYDGERAQVHLLNDGT----MRIYSRNGENMTERYPEI-NITDFIQDLDTTKNLILDCEAVAWDKDQGKILPFQVLSTRKRKDVELNDVKVKVCLFAFDILCYNDERLINKSLKERREYLTKVTKVVPGEFQYATQITTNNLDELQKFLDESVNHSCEGLMVKMLEGPESHYEPSKRSRNWLKLKKDYLEGVGDSLDLCVLGAYYGRGKRTGTYGGFLLGCYNQDTGEFETCCKIGTGFSDEMLQLLHDRLTPTIIDGPKATFVFDSSAEPDVWFEPTTLFEVLTADLSLSPIYKAGSATFD--KGVSLRFPRFLRIREDKGVEDATSSDQIVELYENQSHMQ 754
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BLAST of DNA ligase vs. Ensembl Yeast
Match: DNL4 (DNA ligase required for nonhomologous end-joining (NHEJ); forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth; mutations in human ortholog lead to ligase IV syndrome and Dubowitz syndrome [Source:SGD;Acc:S000005531])

HSP 1 Score: 99.7525 bits (247), Expect = 6.213e-22
Identity = 92/367 (25.07%), Postives = 153/367 (41.69%), Query Frame = 3 
Query: 1209 DHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVK---LIKEILENSSVESCIIDSEAVAWDRETKSILPFQ--KLSTRKKKDVNEVD-IKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQ------------------------------TICRLGTGFTDEDLDNF----YSELKETVTRKPVSSYDYEKSQIPDCWFEP--KYVWEIKAADL 2183
            D  SI  G    P LA       E   R  + DF  E K DGER Q+H     N    I+ FSR   + T  Y   +    + + +    SV+ C++D E V +D + + ILPF   K S ++    N ++ +        FDL+Y N  SL      +R++ L    +       +  S      + I + LE +I    EG+++K  +  ++Y ++ R++NW+K+K +YL++ G+ +DL+VI      G+ + K  +F+L     + E ++                              + C +  G + E+            K T    P +S     S+IP  W +P    V EIK+  L
Sbjct:  244 DDLSIKVGFAFAPQLAKKVNLSYEKICRTLHDDFLVEEKMDGERIQVHY---MNYGESIKFFSRRGIDYTYLYGASLSSGTISQHLRFTDSVKECVLDGEMVTFDAKRRVILPFGLVKGSAKEALSFNSINNVDFHPLYMVFDLLYLNGTSLTPLPLHQRKQYLNSILSPLKNIVEIVRSSRCYGVESIKKSLEVAISLGSEGVVLKYYN--SSYNVASRNNNWIKVKPEYLEEFGENLDLIVI------GRDSGKKDSFMLGLLVLDEEEYKKHQGDSSEIVDHSSQEKHIQNSRRRVKKILSFCSIANGISQEEFKEIDRKTRGHWKRTSEVAPPASILEFGSKIPAEWIDPSESIVLEIKSRSL 599
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BLAST of DNA ligase vs. Ensembl Nematostella
Match: EDO38508 (DNA ligase [Source:UniProtKB/TrEMBL;Acc:A7SCK7])

HSP 1 Score: 692.96 bits (1787), Expect = 0.000e+0
Identity = 338/613 (55.14%), Postives = 444/613 (72.43%), Query Frame = 3 
Query:  573 LSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNES------KLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKTGESAINPYEDDEFY 2393
            LSNF RSVI L+P DLLPCVYLCLNK+AP YEG ELG+G+ ++  A+ +AT      I + +  +GDLGL+A    S+QR +  P KLT  SV+ KLK I+  +G SS   K+DIIK + +A    E +Y++RSL GKLRI LAEQ+VL AL  ++ LTPP+           K+ + D LK ++D     +KT +C+ PNY+ +I +L +YG+ +LP+ C + PGVP+KPMLAHPSKGV+E+ +RF+ S FTCEYKYDGERAQIH+    NG+  I I+SRNQENNTSKYPDI+  + +++ +  ++S IID+EAVAWDRE + ILPFQ LSTRK+KD +  +IK+QVC+YAFDL+Y N +S V+  F  RR +LR +F E  G FV A  + S NT++++EFLE+SIK  CEGLM+KTLD DATYEI+KRSHNWLKLKKDYL  +GDT+DLV IG   G GKR   YG FLLACYD+ESE FQTIC++GTGFTDE L++ +   K+ V  KP   Y Y+    PD WF+   VWE++AADLS+SP H+AAVG VD  KGISLRFPRF+R+R+DKK E AT + Q+AEMYR+QDS+K   +A+   ++++FY
Sbjct:    4 LSNFFRSVIALTPNDLLPCVYLCLNKLAPAYEGIELGIGDHILMKAVSEATGKILSQIKADLADKGDLGLVAEASRSNQRTMFAPPKLTAASVYSKLKDIALFTGHSSTGKKVDIIKGMFVACRHSEARYLIRSLSGKLRIGLAEQSVLTALAHSVVLTPPSSEFPPPVIDAAKTLSSDELKKMLDAGALTVKTCYCELPNYNKIIPALLEYGLEDLPNKCYLTPGVPLKPMLAHPSKGVAEVLKRFEGSAFTCEYKYDGERAQIHLLE--NGE--IHIYSRNQENNTSKYPDIISRMPKVM-SEEIKSFIIDTEAVAWDREKQQILPFQILSTRKRKDADVSEIKVQVCVYAFDLLYLNGKSYVKEPFSVRRNLLRTSFKEAEGEFVFAKCMTSTNTEDMAEFLEESIKGNCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLADVGDTLDLVPIGGYRGKGKRTGAYGGFLLACYDAESEEFQTICKIGTGFTDEVLESHHQFFKDHVIDKPKPYYRYDDGLEPDHWFDAVQVWEVRAADLSVSPVHKAAVGQVDPVKGISLRFPRFLRVRDDKKPEEATDSTQVAEMYRDQDSVKN--NAVTTNQEEDFY 609
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BLAST of DNA ligase vs. Ensembl Nematostella
Match: EDO37995 (DNA ligase [Source:UniProtKB/TrEMBL;Acc:A7SE93])

HSP 1 Score: 186.808 bits (473), Expect = 3.399e-49
Identity = 134/371 (36.12%), Postives = 190/371 (51.21%), Query Frame = 3 
Query: 1233 VPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVE--SCIIDSEAVAWDRETKSILPFQKLSTRKK---KDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDK--MGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELK-----ETVTRKPVSSYDYEKSQIPDCWF-EPKY--VWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENAT 2300
             P+KPMLA   K  S   ++        E KYDGER Q+H S       K + FSR+ +      P  V   ++ L  +     + I+D E +  D +T   LPF  L   KK   KD N       VCL+ FD + FN+++++  S  ERRKIL EN T  P   +L+ +    +  ++S+ + ++++D  EGL++K  D    YE  KR  +WLK+KKDYL++  M DT DLVV+GA YGTG +      FL+  ++   + + T+ + G G  D+ LD    ELK     +   R PV   +  +S IPD    +PK   VWEI  A+ S S  H A         GIS+RFPR  RIR+DK  E AT
Sbjct:  429 TPVKPMLAEACKTFSYAIKKCPKG-MLAEIKYDGERVQVHKSGS-----KFEFFSRSLK---PVLPHKVSAFRDFLPKACPHGNNLILDCEVLLVDNKTSLPLPFGTLGIHKKSAFKDAN-------VCLFIFDCLQFNEENVMRKSMTERRKILEENVTVIPNRIMLSETTFVKDEKKLSQLMARAMRDGLEGLVLK--DVTGQYEPGKR--HWLKMKKDYLEEGSMADTADLVVLGAYYGTGNKGGLMSVFLMGVFNPRIKKWCTVAKCGNGHDDKTLDKLNRELKVKKISKDPNRVPV-WLEVHRSLIPDFVVDDPKKAPVWEITGAEFSKSTTHTA--------DGISIRFPRVTRIRDDKDWETAT 770
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BLAST of DNA ligase vs. Ensembl Nematostella
Match: EDO35746 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKL4])

HSP 1 Score: 118.627 bits (296), Expect = 2.278e-27
Identity = 100/368 (27.17%), Postives = 167/368 (45.38%), Query Frame = 3 
Query: 1239 IKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKI-----QVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRS-HNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACY---DSESE---LFQTICRLGTGFTDEDLDNFYSELKETV----TRKPVSSYDYEKS--QIPDCWFEP--KYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDK 2282
             +PMLA  S  ++++     N  F  E K DGER  +H   D     K + FSR   + T  + +           +S E C+       ++R      P Q +     +    +   +     Q C   FD++ +N + L  +   ER K+L   F    GF       ++ + +E+ + L ++I  + EGL++K+   D+ Y+ + R+   WLK+K +Y+  + D +D+V++G  +G G+R      FL A     D   E    F ++C++G+G+T  +LD    +LK         KP  S  +     + PD W EP    V +IKAA+++ S  +RA         G +LRFPR   +R DK
Sbjct:  246 FRPMLAQWSP-LNQVEDLMKNQPFYIETKMDGERFILHKDGD-----KYRYFSRGGNDFTHTFGE-----------NSREGCLTPKINDCFERLISISSPGQSIHAFWMERCWFMTHPMKFLFRQPCFVVFDVLLYNGKKLANTPLHERLKLLETVFKPCLGFLQFVERQNASSNEEVIKSLNEAIDRREEGLVVKS--RDSVYKPNVRNGGGWLKIKPEYVASLSDDLDVVIVGGYFGVGRRQGMVSHFLCAVAVPSDRRGEKPSQFYSLCKVGSGYTMNELDELGQQLKPHWQPFNQAKPPKSVCFTPGFKEKPDVWIEPSKSKVVQIKAAEITPSEKYRA---------GFTLRFPRLECVRHDK 585
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BLAST of DNA ligase vs. Ensembl Medaka
Match: lig1 (DNA ligase 1 [Source:NCBI gene;Acc:101167483])

HSP 1 Score: 754.592 bits (1947), Expect = 0.000e+0
Identity = 361/654 (55.20%), Postives = 475/654 (72.63%), Query Frame = 3 
Query:  429 SEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNE----SKLDKSQNF--DSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKTGESAINP 2372
            +E+DP    YH ++ ACWK ++K+PYLA+A+TFE IE  + RL    TLSN  RSV+ LSP DLL CVYLCLN++ P Y G ELGVGE V+  A+ QAT      I +  +++GDLGL+A +  S+QR + QPA LTV SVF+KLK I+  SG S+   KIDIIK L +A    E +YIVRSL GKLRI LAEQ+VL+AL QA+ LTPP +    + +D S+    +S +  I++ + I+K  +C+ PNYD+++  L K GI  LP+HC + PGVP++PMLAHP+KGV E+ ++FD + FTCEYKYDGERAQIH+        +++IFSRNQE+NTSKYPDI+  I ++ +  SV SC++DSEAVAWD E K I PFQ L+TRK+KDV+  +IK+QVC+YAFDL+Y N +SLV      RR +LR++F E  G F+ A S+DS +TD I+EFLEQS++D CEGLM+KTL+ DATYEI+KRSHNWLKLKKDYLD +GDTVDL VIGA  G GKR   YG FLLACYD E+E FQ++C++GTGF DEDL+  Y  LKE +  KP + Y  ++S  PD W +   VWE+K ADLS+SP ++AA+GLVD EKGISLRFPRF+RIR+DKK E+AT+  Q+A++Y+ Q  ++      +P
Sbjct:  341 TEFDPSRPNYHPVDHACWKHSQKVPYLAVARTFEKIEEDSGRLRNIETLSNLFRSVLLLSPDDLLCCVYLCLNQLGPAYLGMELGVGETVLMKAVAQATGRQLDKIKAEAQEKGDLGLVAESSRSNQRMMFQPASLTVGSVFKKLKEIASMSGNSAMNKKIDIIKGLFVACRFSEARYIVRSLAGKLRIGLAEQSVLSALSQAVCLTPPGQDFPPAVIDASKGMSAESRRAWIEEKSLILKQTYCEMPNYDIILPVLLKEGIDQLPNHCKLTPGVPLRPMLAHPTKGVGEVMKKFDEAAFTCEYKYDGERAQIHILESG----EVRIFSRNQEDNTSKYPDIIARIPKV-KKESVVSCVLDSEAVAWDHEKKQIQPFQVLTTRKRKDVDASEIKVQVCVYAFDLLYLNGESLVRQPLCRRRALLRDSFMEVEGEFMFARSIDSDSTDAIAEFLEQSVRDSCEGLMVKTLEKDATYEIAKRSHNWLKLKKDYLDGVGDTVDLCVIGAYLGKGKRTGTYGGFLLACYDDENEEFQSVCKIGTGFKDEDLEQHYKFLKEHILPKPRAYYRVDQSAEPDVWLDAVQVWEVKCADLSLSPVYKAAMGLVDPEKGISLRFPRFLRIRDDKKPEDATSGSQMADLYKKQQQIQNQGDKADP 989
[Close]
BLAST of DNA ligase vs. Ensembl Medaka
Match: lig1 (DNA ligase 1 [Source:NCBI gene;Acc:101167483])

HSP 1 Score: 721.079 bits (1860), Expect = 0.000e+0
Identity = 351/654 (53.67%), Postives = 462/654 (70.64%), Query Frame = 3 
Query:  429 SEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNE----SKLDKSQNF--DSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKTGESAINP 2372
            +E+DP    YH ++ ACWK ++K+PYLA+A+TFE IE  + RL    TLSN  RSV+ LSP DLL CVYLCLN++ P Y G ELGVGE V+  A+ QAT      I +  +++GDLGL+A +  S+QR + QPA LTV SVF+KLK I+  SG S+   KIDIIK L +A    E +YIVRSL GKLRI LAEQ+VL+AL QA+ LTPP +    + +D S+    +S +  I++ + I+K  +C+ PNYD+++  L K GI  LP+HC + PGVP++PMLAHP+KGV E+ ++FD + FTCEYKYDGERAQIH+        +++IFSRNQE+NTSKYPDI+  I ++ +  SV SC++DSEAVAWD E K I PFQ L+TRK+KDV+  +IK+QVC+YAFDL+Y N +SLV      RR +LR++F E  G F+ A S+DS +TD I+EFLEQS++D CEGLM+KTL+ DATYEI+KRSHNWLKLKKDYLD +GDTVDL VIGA  G GKR   YG FLLACYD E+E FQ++C                  KE +  KP + Y  ++S  PD W +   VWE+K ADLS+SP ++AA+GLVD EKGISLRFPRF+RIR+DKK E+AT+  Q+A++Y+ Q  ++      +P
Sbjct:  341 TEFDPSRPNYHPVDHACWKHSQKVPYLAVARTFEKIEEDSGRLRNIETLSNLFRSVLLLSPDDLLCCVYLCLNQLGPAYLGMELGVGETVLMKAVAQATGRQLDKIKAEAQEKGDLGLVAESSRSNQRMMFQPASLTVGSVFKKLKEIASMSGNSAMNKKIDIIKGLFVACRFSEARYIVRSLAGKLRIGLAEQSVLSALSQAVCLTPPGQDFPPAVIDASKGMSAESRRAWIEEKSLILKQTYCEMPNYDIILPVLLKEGIDQLPNHCKLTPGVPLRPMLAHPTKGVGEVMKKFDEAAFTCEYKYDGERAQIHILESG----EVRIFSRNQEDNTSKYPDIIARIPKV-KKESVVSCVLDSEAVAWDHEKKQIQPFQVLTTRKRKDVDASEIKVQVCVYAFDLLYLNGESLVRQPLCRRRALLRDSFMEVEGEFMFARSIDSDSTDAIAEFLEQSVRDSCEGLMVKTLEKDATYEIAKRSHNWLKLKKDYLDGVGDTVDLCVIGAYLGKGKRTGTYGGFLLACYDDENEEFQSVC------------------KEHILPKPRAYYRVDQSAEPDVWLDAVQVWEVKCADLSLSPVYKAAMGLVDPEKGISLRFPRFLRIRDDKKPEDATSGSQMADLYKKQQQIQNQGDKADP 971
[Close]
BLAST of DNA ligase vs. Ensembl Medaka
Match: lig3 (DNA ligase 3 [Source:NCBI gene;Acc:101156760])

HSP 1 Score: 194.126 bits (492), Expect = 5.788e-51
Identity = 131/385 (34.03%), Postives = 190/385 (49.35%), Query Frame = 3 
Query: 1233 VPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENS--SVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDK--MGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWF---------------EPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYR 2330
             P++PMLA   K + +  ++  N  +  E KYDGER Q+H S D+        FSR+ +      P  V   K+ +  +     S I+D+E +  D ++   LPF  L   KK    + +    VCL+ FD IYFN  SL+E   +ERRK L +N  E P   + +         ++++ + + I++  EGL++K  D  +TYE  KR  +WLK+KKDYL++  M DT DLVV+GA YG G       +FL+ CYD +S+ + T+ +   G+ D  L     EL        V     E S+IP  W                E   VWEI  A+ S S  H A         GIS+RFPR  RIR+DK  + AT   Q+ E++R
Sbjct:  481 TPVQPMLAEACKSIDQAMKKCPNGMYA-EIKYDGERVQVHKSGDS-----FSYFSRSLK---PVLPHKVAHFKDYIPQAFPGGHSMILDAEVLLIDTKSSKPLPFGTLGIHKKAAFQDAN----VCLFVFDCIYFNGVSLMERPLKERRKFLTDNMVEVPNRILFSEMKHVTRAGDLADMITRVIREGLEGLVLK--DIKSTYEPGKR--HWLKVKKDYLNEGAMADTADLVVLGAFYGKGSNGGIMSSFLMGCYDPDSKKWCTVTKCSGGYDDAMLARLQKELD-------VIKISKEPSKIPG-WLKIVKNYYPDFIIRDPEKAPVWEITGAEFSKSEMHTA--------DGISIRFPRMTRIRDDKDWKTATNLHQLRELFR 832
[Close]
BLAST of DNA ligase vs. Ensembl Medaka
Match: lig3 (DNA ligase 3 [Source:NCBI gene;Acc:101156760])

HSP 1 Score: 193.741 bits (491), Expect = 7.602e-51
Identity = 131/385 (34.03%), Postives = 190/385 (49.35%), Query Frame = 3 
Query: 1233 VPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENS--SVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDK--MGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWF---------------EPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYR 2330
             P++PMLA   K + +  ++  N  +  E KYDGER Q+H S D+        FSR+ +      P  V   K+ +  +     S I+D+E +  D ++   LPF  L   KK    + +    VCL+ FD IYFN  SL+E   +ERRK L +N  E P   + +         ++++ + + I++  EGL++K  D  +TYE  KR  +WLK+KKDYL++  M DT DLVV+GA YG G       +FL+ CYD +S+ + T+ +   G+ D  L     EL        V     E S+IP  W                E   VWEI  A+ S S  H A         GIS+RFPR  RIR+DK  + AT   Q+ E++R
Sbjct:  481 TPVQPMLAEACKSIDQAMKKCPNGMYA-EIKYDGERVQVHKSGDS-----FSYFSRSLK---PVLPHKVAHFKDYIPQAFPGGHSMILDAEVLLIDTKSSKPLPFGTLGIHKKAAFQDAN----VCLFVFDCIYFNGVSLMERPLKERRKFLTDNMVEVPNRILFSEMKHVTRAGDLADMITRVIREGLEGLVLK--DIKSTYEPGKR--HWLKVKKDYLNEGAMADTADLVVLGAFYGKGSNGGIMSSFLMGCYDPDSKKWCTVTKCSGGYDDAMLARLQKELD-------VIKISKEPSKIPG-WLKIVKNYYPDFIIRDPEKAPVWEITGAEFSKSEMHTA--------DGISIRFPRMTRIRDDKDWKTATNLHQLRELFR 832
[Close]
BLAST of DNA ligase vs. Ensembl Medaka
Match: lig4 (DNA ligase 4 [Source:NCBI gene;Acc:101166453])

HSP 1 Score: 153.68 bits (387), Expect = 5.092e-38
Identity = 133/484 (27.48%), Postives = 237/484 (48.97%), Query Frame = 3 
Query:  924 NLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESKLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYP------DIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDS-----ESELFQTICRLGTGFTDEDLDNFYSELKET--VTRK--PVSSYDYEKSQIPDCWFEP--KYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEM 2324
            +L+  SS  E+K+++R +L  +++ ++++TVL A         P+ ++L             + NT + K   CQ          L    +S L D  SI      KPMLA  +  +  + ++  NS F  E K DGER Q+H   D       + FSRN    T ++        +   I  + + S V +CI+D E +A++  T++ +  QK S    K + + D ++Q C   FD++  NDQ L + + R+R +IL+  FT   G   L    ++ +  E+   L  +I  + EG+M+K  D  + Y+  KR   WLK+K +Y+D + D +DL+++G  +G G+R      FL A  ++     +  +F ++CR+G+G+T ++L +   +L +   V R+  P  S     ++ P+ + EP    + ++KAA++  S  +R            +LRFPR  +IR+DK+     T  ++ ++
Sbjct:  179 HLITQSSALEQKWLIRMILKDMKLGISKETVLQAFH-------PDAAEL------------YNVNTDLNKV--CQ---------QLHNPSVS-LSD-VSIGLFSAFKPMLAAVAN-IRNVEKQMGNSPFYIETKLDGERIQLHKDGDV-----YKYFSRNAFEYTQQFGGSPLEGSLTPYIHNVFK-SHVANCILDGEMMAYNPTTETFM--QKGSRFDIKKLMD-DSELQTCFCVFDVLLVNDQKLGKEALRKRHEILQTVFTPAKGRMHLVPKSEARSVQEVVSALNDAIDSREEGIMVK--DPLSIYKPDKRGEGWLKIKPEYVDSLMDELDLLIVGGYWGKGRRGGMMSHFLCAVAEAPKPGEKPSVFHSLCRIGSGYTMKELYDLGLKLAKHWKVYRRSDPPPSL-LCSTEKPEVYIEPCNSIIVQVKAAEIIPSDMYRT---------NCTLRFPRIEKIRDDKEWHQCMTLAELDQL 608
[Close]
BLAST of DNA ligase vs. Planmine SMEST
Match: SMESG000046648.1 (SMESG000046648.1)

HSP 1 Score: 1484.16 bits (3841), Expect = 0.000e+0
Identity = 749/754 (99.34%), Postives = 750/754 (99.47%), Query Frame = 3 
Query:  132 MGSTKIQKLEVKLKRKSDSPIKYENTDEVIAISKTKKRKTFLXXXXXXXXXXXXXXXXXXXXXLNDEIKALPKKELNCIKTDDLNQTEIETVEKVNKIPSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESKLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTARQIAEMYRNQDSMKTGESAINPYEDDEFY 2393
            MGSTKIQKLEVKLKRKSDSPIKYENTDEVIAI KTKKRKTFLDSDSDSNDISIKKPNKKISNNLNDEIKALPKKELNCIKTDDLNQTEIETVEKVNKIPSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSP DLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESKLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSIC GVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDA GKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATT+RQIAEMYRNQDSMKTGESAINPYEDDEFY
Sbjct:    1 MGSTKIQKLEVKLKRKSDSPIKYENTDEVIAILKTKKRKTFLDSDSDSNDISIKKPNKKISNNLNDEIKALPKKELNCIKTDDLNQTEIETVEKVNKIPSEYDPMINPYHIINDACWKPNEKIPYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPNDLLPCVYLCLNKVAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESKLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICSGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDAKGKRKIQIFSRNQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESELFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEPKYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENATTSRQIAEMYRNQDSMKTGESAINPYEDDEFY 754
[Close]
BLAST of DNA ligase vs. Planmine SMEST
Match: SMESG000020186.1 (SMESG000020186.1)

HSP 1 Score: 114.005 bits (284), Expect = 8.887e-26
Identity = 133/554 (24.01%), Postives = 246/554 (44.40%), Query Frame = 3 
Query:  771 DLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESKLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKY---PDIVKLIKEILEN--SSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKP--GFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSES--ELFQTICRLGTGFTDEDLDNFYSELKETVTR-KPVSSYDYEK-----SQIPDCWFEPK--YVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKA-ENATTARQIAEMYRNQDSMKTGESAINPYE 2378
            D   I YN+  ++        LT+  +   L  +S  SG+  N    + ++ L   ++  ++K+++R +L  L I L+ + +           P +E   +++ + + +                 C  +  L +++  +          +C   P KPML+     +  +  + +N  F  E KYDGER Q+H           + +SR+    T+ Y   P    L + I     S V++CI+D E + ++ ET ++    K      K+ N        C   FD++Y N++ L      +R+KIL  +  E    G  +++   ++   +E  E    +I++  EG+M+K    D+ Y+ + RS  W K+K DY+  + + +D V++G  +  GK   +   FL A   +ES    + +  RL +GF+ + + +F ++      R K  S  ++ K      +IPD   EPK  +V ++KAA++ IS +  A           +LRF R    REDK    +  T +Q+ E+ +N +    G+ A++P E
Sbjct:  110 DFAEITYNVLKNR--CSNKDSLTLEEINSALDKLSEASGRLKNEIIEENLRFLFQKTTALDQKWLIRIILKDLSIGLSNKAIFKCFH------PLSEECYNETTDLNLV-----------------CEKFKSLTDNIASF---------DVCIFKPFKPMLSKRG-DIKNVLGQVNNQPFIIEVKYDGERVQLH-----KFGSNYRYWSRSGLEWTNSYGMDPCNGTLTRFIYNQFKSDVDNCILDGEMMGFNIETDTMGC--KTDKFDIKNPNVEKTGYLPCFIVFDVLYLNNKVLTHEKLLDRKKILENDILESELNGKIMISKWTEASTREECLEAFNSAIENCEEGIMVKR--TDSIYKTNSRSAGWFKMKPDYVLGLHEELDCVIVGGYFSCGKLIRQ---FLCAVKSNESPNHQYYSFVRLCSGFSRKMIFDFNAKTAPFWKRCKKESIPEWLKLSEKGKEIPDVVIEPKDSFVVQLKAAEI-ISSESYAT--------KCTLRFCRIDCFREDKSPITDCMTVKQLHEL-KNSNK---GKLALHPLE 603
[Close]
BLAST of DNA ligase vs. Planmine SMEST
Match: SMESG000020186.1 (SMESG000020186.1)

HSP 1 Score: 114.005 bits (284), Expect = 9.516e-26
Identity = 133/554 (24.01%), Postives = 246/554 (44.40%), Query Frame = 3 
Query:  771 DLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESKLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKY---PDIVKLIKEILEN--SSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKP--GFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSES--ELFQTICRLGTGFTDEDLDNFYSELKETVTR-KPVSSYDYEK-----SQIPDCWFEPK--YVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKA-ENATTARQIAEMYRNQDSMKTGESAINPYE 2378
            D   I YN+  ++        LT+  +   L  +S  SG+  N    + ++ L   ++  ++K+++R +L  L I L+ + +           P +E   +++ + + +                 C  +  L +++  +          +C   P KPML+     +  +  + +N  F  E KYDGER Q+H           + +SR+    T+ Y   P    L + I     S V++CI+D E + ++ ET ++    K      K+ N        C   FD++Y N++ L      +R+KIL  +  E    G  +++   ++   +E  E    +I++  EG+M+K    D+ Y+ + RS  W K+K DY+  + + +D V++G  +  GK   +   FL A   +ES    + +  RL +GF+ + + +F ++      R K  S  ++ K      +IPD   EPK  +V ++KAA++ IS +  A           +LRF R    REDK    +  T +Q+ E+ +N +    G+ A++P E
Sbjct:  110 DFAEITYNVLKNR--CSNKDSLTLEEINSALDKLSEASGRLKNEIIEENLRFLFQKTTALDQKWLIRIILKDLSIGLSNKAIFKCFH------PLSEECYNETTDLNLV-----------------CEKFKSLTDNIASF---------DVCIFKPFKPMLSKRG-DIKNVLGQVNNQPFIIEVKYDGERVQLH-----KFGSNYRYWSRSGLEWTNSYGMDPCNGTLTRFIYNQFKSDVDNCILDGEMMGFNIETDTMGC--KTDKFDIKNPNVEKTGYLPCFIVFDVLYLNNKVLTHEKLLDRKKILENDILESELNGKIMISKWTEASTREECLEAFNSAIENCEEGIMVKR--TDSIYKTNSRSAGWFKMKPDYVLGLHEELDCVIVGGYFSCGKLIRQ---FLCAVKSNESPNHQYYSFVRLCSGFSRKMIFDFNAKTAPFWKRCKKESIPEWLKLSEKGKEIPDVVIEPKDSFVVQLKAAEI-ISSESYAT--------KCTLRFCRIDCFREDKSPITDCMTVKQLHEL-KNSNK---GKLALHPLE 603
[Close]
BLAST of DNA ligase vs. Planmine SMEST
Match: SMESG000020186.1 (SMESG000020186.1)

HSP 1 Score: 114.005 bits (284), Expect = 1.006e-25
Identity = 133/554 (24.01%), Postives = 246/554 (44.40%), Query Frame = 3 
Query:  771 DLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESKLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKY---PDIVKLIKEILEN--SSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKP--GFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSES--ELFQTICRLGTGFTDEDLDNFYSELKETVTR-KPVSSYDYEK-----SQIPDCWFEPK--YVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKA-ENATTARQIAEMYRNQDSMKTGESAINPYE 2378
            D   I YN+  ++        LT+  +   L  +S  SG+  N    + ++ L   ++  ++K+++R +L  L I L+ + +           P +E   +++ + + +                 C  +  L +++  +          +C   P KPML+     +  +  + +N  F  E KYDGER Q+H           + +SR+    T+ Y   P    L + I     S V++CI+D E + ++ ET ++    K      K+ N        C   FD++Y N++ L      +R+KIL  +  E    G  +++   ++   +E  E    +I++  EG+M+K    D+ Y+ + RS  W K+K DY+  + + +D V++G  +  GK   +   FL A   +ES    + +  RL +GF+ + + +F ++      R K  S  ++ K      +IPD   EPK  +V ++KAA++ IS +  A           +LRF R    REDK    +  T +Q+ E+ +N +    G+ A++P E
Sbjct:  110 DFAEITYNVLKNR--CSNKDSLTLEEINSALDKLSEASGRLKNEIIEENLRFLFQKTTALDQKWLIRIILKDLSIGLSNKAIFKCFH------PLSEECYNETTDLNLV-----------------CEKFKSLTDNIASF---------DVCIFKPFKPMLSKRG-DIKNVLGQVNNQPFIIEVKYDGERVQLH-----KFGSNYRYWSRSGLEWTNSYGMDPCNGTLTRFIYNQFKSDVDNCILDGEMMGFNIETDTMGC--KTDKFDIKNPNVEKTGYLPCFIVFDVLYLNNKVLTHEKLLDRKKILENDILESELNGKIMISKWTEASTREECLEAFNSAIENCEEGIMVKR--TDSIYKTNSRSAGWFKMKPDYVLGLHEELDCVIVGGYFSCGKLIRQ---FLCAVKSNESPNHQYYSFVRLCSGFSRKMIFDFNAKTAPFWKRCKKESIPEWLKLSEKGKEIPDVVIEPKDSFVVQLKAAEI-ISSESYAT--------KCTLRFCRIDCFREDKSPITDCMTVKQLHEL-KNSNK---GKLALHPLE 603
[Close]
BLAST of DNA ligase vs. Planmine SMEST
Match: SMESG000020186.1 (SMESG000020186.1)

HSP 1 Score: 114.005 bits (284), Expect = 1.472e-25
Identity = 133/554 (24.01%), Postives = 246/554 (44.40%), Query Frame = 3 
Query:  771 DLGLIAYNLPSSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKCERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESKLDKSQNFDSLKPIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPMLAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSRNQENNTSKY---PDIVKLIKEILEN--SSVESCIIDSEAVAWDRETKSILPFQKLSTRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTEKP--GFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKRSHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSES--ELFQTICRLGTGFTDEDLDNFYSELKETVTR-KPVSSYDYEK-----SQIPDCWFEPK--YVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKA-ENATTARQIAEMYRNQDSMKTGESAINPYE 2378
            D   I YN+  ++        LT+  +   L  +S  SG+  N    + ++ L   ++  ++K+++R +L  L I L+ + +           P +E   +++ + + +                 C  +  L +++  +          +C   P KPML+     +  +  + +N  F  E KYDGER Q+H           + +SR+    T+ Y   P    L + I     S V++CI+D E + ++ ET ++    K      K+ N        C   FD++Y N++ L      +R+KIL  +  E    G  +++   ++   +E  E    +I++  EG+M+K    D+ Y+ + RS  W K+K DY+  + + +D V++G  +  GK   +   FL A   +ES    + +  RL +GF+ + + +F ++      R K  S  ++ K      +IPD   EPK  +V ++KAA++ IS +  A           +LRF R    REDK    +  T +Q+ E+ +N +    G+ A++P E
Sbjct:  110 DFAEITYNVLKNR--CSNKDSLTLEEINSALDKLSEASGRLKNEIIEENLRFLFQKTTALDQKWLIRIILKDLSIGLSNKAIFKCFH------PLSEECYNETTDLNLV-----------------CEKFKSLTDNIASF---------DVCIFKPFKPMLSKRG-DIKNVLGQVNNQPFIIEVKYDGERVQLH-----KFGSNYRYWSRSGLEWTNSYGMDPCNGTLTRFIYNQFKSDVDNCILDGEMMGFNIETDTMGC--KTDKFDIKNPNVEKTGYLPCFIVFDVLYLNNKVLTHEKLLDRKKILENDILESELNGKIMISKWTEASTREECLEAFNSAIENCEEGIMVKR--TDSIYKTNSRSAGWFKMKPDYVLGLHEELDCVIVGGYFSCGKLIRQ---FLCAVKSNESPNHQYYSFVRLCSGFSRKMIFDFNAKTAPFWKRCKKESIPEWLKLSEKGKEIPDVVIEPKDSFVVQLKAAEI-ISSESYAT--------KCTLRFCRIDCFREDKSPITDCMTVKQLHEL-KNSNK---GKLALHPLE 603
The following BLAST results are available for this feature:
BLAST of DNA ligase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
LIG10.000e+053.03DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598][more]
LIG10.000e+053.03DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598][more]
LIG10.000e+053.03DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598][more]
LIG10.000e+053.43DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598][more]
LIG10.000e+053.43DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598][more]
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BLAST of DNA ligase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
lig-10.000e+048.07DNA ligase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q27... [more]
lig-13.960e-4141.33DNA ligase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q27... [more]
lig-41.822e-1022.44LIGase [Source:UniProtKB/TrEMBL;Acc:Q95YE6][more]
lig-41.822e-1022.44LIGase [Source:UniProtKB/TrEMBL;Acc:Q95YE6][more]
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BLAST of DNA ligase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
DNAlig10.000e+052.82gene:FBgn0262619 transcript:FBtr0072132[more]
DNAlig37.721e-4733.07gene:FBgn0286075 transcript:FBtr0082600[more]
DNAlig42.169e-2123.79gene:FBgn0030506 transcript:FBtr0073847[more]
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BLAST of DNA ligase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lig10.000e+056.16ligase I, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB-... [more]
lig10.000e+056.16ligase I, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB-... [more]
lig10.000e+054.50ligase I, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB-... [more]
lig36.894e-4934.29ligase III, DNA, ATP-dependent [Source:ZFIN;Acc:ZD... [more]
lig42.091e-3423.74ligase IV, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB... [more]
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BLAST of DNA ligase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
golga50.000e+056.90golgin A5 [Source:Xenbase;Acc:XB-GENE-1014825][more]
golga50.000e+054.88golgin A5 [Source:Xenbase;Acc:XB-GENE-1014825][more]
golga50.000e+056.79golgin A5 [Source:Xenbase;Acc:XB-GENE-1014825][more]
golga50.000e+054.75golgin A5 [Source:Xenbase;Acc:XB-GENE-1014825][more]
golga50.000e+055.77golgin A5 [Source:Xenbase;Acc:XB-GENE-1014825][more]
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BLAST of DNA ligase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Lig10.000e+054.29ligase I, DNA, ATP-dependent [Source:MGI Symbol;Ac... [more]
Lig10.000e+054.29ligase I, DNA, ATP-dependent [Source:MGI Symbol;Ac... [more]
Lig10.000e+054.29ligase I, DNA, ATP-dependent [Source:MGI Symbol;Ac... [more]
Lig34.658e-5034.38ligase III, DNA, ATP-dependent [Source:MGI Symbol;... [more]
Lig36.707e-5034.38ligase III, DNA, ATP-dependent [Source:MGI Symbol;... [more]
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BLAST of DNA ligase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P51892|DNLI1_XENLA0.000e+054.92DNA ligase 1 OS=Xenopus laevis OX=8355 GN=lig1 PE=... [more]
sp|P18858|DNLI1_HUMAN0.000e+053.03DNA ligase 1 OS=Homo sapiens OX=9606 GN=LIG1 PE=1 ... [more]
sp|P37913|DNLI1_MOUSE0.000e+054.29DNA ligase 1 OS=Mus musculus OX=10090 GN=Lig1 PE=1... [more]
sp|Q9JHY8|DNLI1_RAT0.000e+052.42DNA ligase 1 OS=Rattus norvegicus OX=10116 GN=Lig1... [more]
sp|Q9W1H4|DNLI1_DROME0.000e+052.82DNA ligase 1 OS=Drosophila melanogaster OX=7227 GN... [more]
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BLAST of DNA ligase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A098LZ920.000e+055.89DNA ligase OS=Hypsiglena sp. JMG-2014 OX=1550645 P... [more]
H9GHC90.000e+056.04DNA ligase OS=Anolis carolinensis OX=28377 GN=LIG1... [more]
A0A402FQ340.000e+055.72DNA ligase OS=Paroedura picta OX=143630 GN=parPi_0... [more]
A0A210PFJ60.000e+056.01DNA ligase OS=Mizuhopecten yessoensis OX=6573 GN=K... [more]
A0A2B4RKL20.000e+055.49DNA ligase OS=Stylophora pistillata OX=50429 GN=li... [more]
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BLAST of DNA ligase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
lig10.000e+055.57ligase I, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB-... [more]
lig39.324e-4433.25DNA ligase 3 [Source:NCBI gene;Acc:103047681][more]
lig41.208e-3426.02ligase IV, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB... [more]
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BLAST of DNA ligase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
lig14.677e-13351.04ligase I, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB-... [more]
lig31.177e-4133.77ligase III, DNA, ATP-dependent [Source:ZFIN;Acc:ZD... [more]
lig41.502e-2726.22ligase IV, DNA, ATP-dependent [Source:ZFIN;Acc:ZDB... [more]
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BLAST of DNA ligase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
CDC91.392e-17744.19DNA ligase I found in nucleus and mitochondria; es... [more]
DNL46.213e-2225.07DNA ligase required for nonhomologous end-joining ... [more]
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BLAST of DNA ligase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO385080.000e+055.14DNA ligase [Source:UniProtKB/TrEMBL;Acc:A7SCK7][more]
EDO379953.399e-4936.12DNA ligase [Source:UniProtKB/TrEMBL;Acc:A7SE93][more]
EDO357462.278e-2727.17Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of DNA ligase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lig10.000e+055.20DNA ligase 1 [Source:NCBI gene;Acc:101167483][more]
lig10.000e+053.67DNA ligase 1 [Source:NCBI gene;Acc:101167483][more]
lig35.788e-5134.03DNA ligase 3 [Source:NCBI gene;Acc:101156760][more]
lig37.602e-5134.03DNA ligase 3 [Source:NCBI gene;Acc:101156760][more]
lig45.092e-3827.48DNA ligase 4 [Source:NCBI gene;Acc:101166453][more]
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BLAST of DNA ligase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000046648.10.000e+099.34SMESG000046648.1[more]
SMESG000020186.18.887e-2624.01SMESG000020186.1[more]
SMESG000020186.19.516e-2624.01SMESG000020186.1[more]
SMESG000020186.11.006e-2524.01SMESG000020186.1[more]
SMESG000020186.11.472e-2524.01SMESG000020186.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010896 ID=SMED30010896|Name=DNA ligase|organism=Schmidtea mediterranea sexual|type=transcript|length=2459bp
TTCCGATCTGTTGTTTTAATATTAGTAGTTTAAAGTTATAAAAAAGAATA
ATGAAACAAACTTCTATTTCACAATTTTTTGGATCCAATACAACAAAGAA
AAATGTAGAAGATATTTCAAACAAAGATAAAATGGGCTCTACGAAAATAC
AGAAATTAGAAGTTAAACTTAAACGAAAGTCTGATTCTCCAATTAAATAT
GAAAATACTGATGAAGTTATAGCGATCTCAAAGACAAAAAAGCGAAAAAC
TTTTCTTGATTCTGACTCTGACAGTAATGATATTTCAATAAAAAAGCCAA
ATAAAAAAATATCTAATAATTTGAATGATGAGATAAAAGCATTACCAAAA
AAAGAATTAAATTGCATTAAAACGGATGATTTAAATCAAACAGAAATTGA
AACAGTTGAAAAAGTTAATAAGATCCCGAGCGAATATGATCCTATGATAA
ATCCTTATCATATCATAAATGACGCATGTTGGAAACCAAATGAAAAAATT
CCATACTTAGCATTAGCAAAAACATTTGAGGTCATAGAATCAACTACTAA
AAGATTGGAAATAACTCGAACGTTGAGCAACTTCATGAGATCTGTAATAT
ATCTCTCACCGAAAGATTTATTGCCTTGTGTTTATTTGTGCTTGAATAAG
GTGGCCCCGGACTATGAAGGTGCCGAATTAGGTGTCGGTGAAGCTGTCGT
AAAAAATGCATTAATACAGGCCACAGATGTTGACAAAAAGACAATAGATT
CGAGAATGAAGAAAGAAGGCGATCTCGGTTTAATTGCATATAATCTTCCC
AGCTCTCAACGATACCTAGTTCAACCGGCTAAATTAACTGTGCCATCTGT
GTTTCAGAAATTAAAAATTATTTCTGGAACAAGTGGTAAATCCTCGAACA
CCAACAAGATTGACATAATAAAAAATCTACTAATCGCTTCGAGTAAATGT
GAGAGAAAATATATTGTTAGAAGTTTGTTGGGAAAATTGCGCATCAGATT
GGCAGAACAAACTGTTTTAGCAGCCCTCGGTCAGGCCATCACATTGACTC
CACCTAATGAATCGAAATTAGATAAATCTCAAAATTTTGATTCATTAAAG
CCAATCATCGATAAGAACACTGCGATAATCAAGACTGCATTTTGCCAATG
CCCCAATTACGATCTTTTAATTGAATCTCTATTCAAATATGGGATATCCA
ATTTACCAGATCATTGTTCCATTTGCCCCGGAGTTCCTATCAAGCCAATG
TTGGCACATCCTTCCAAGGGTGTTTCGGAGATATTTCAAAGGTTTGATAA
CTCAGATTTTACATGCGAATACAAATATGACGGAGAACGAGCTCAAATTC
ACGTATCAACTGATGCCAATGGAAAACGAAAAATTCAAATATTTTCCAGA
AATCAAGAAAATAATACCTCAAAGTATCCAGATATTGTCAAATTGATAAA
GGAAATCCTCGAAAACAGCAGTGTTGAATCCTGTATTATTGACTCAGAGG
CAGTAGCCTGGGACAGAGAAACTAAGTCTATTTTACCATTTCAAAAATTG
TCTACAAGAAAGAAAAAAGATGTCAATGAAGTTGATATTAAAATACAGGT
CTGCCTATACGCATTTGATCTCATCTATTTCAATGACCAATCATTGGTTG
AGAGCTCTTTCAGGGAACGTCGAAAAATTCTCAGAGAAAACTTTACCGAA
AAACCTGGATTTTTCGTTCTCGCTACTTCTCTCGATTCATGTAATACTGA
TGAAATATCGGAATTTTTGGAACAGTCTATAAAAGACAAATGTGAAGGCC
TGATGATTAAGACATTAGATAATGATGCAACTTATGAAATTTCAAAACGA
TCTCATAATTGGTTAAAGCTGAAAAAGGACTATCTAGATAAAATGGGCGA
CACGGTCGATTTAGTGGTTATCGGTGCTTGTTATGGCACCGGTAAACGAG
CCAATAAATATGGCACATTTCTGTTGGCTTGCTATGACTCGGAATCGGAA
CTATTTCAAACTATCTGCAGATTGGGTACCGGATTTACTGATGAGGATTT
AGACAACTTTTACAGCGAATTAAAAGAAACCGTTACCCGAAAACCAGTCA
GCAGTTATGATTATGAGAAATCCCAGATACCCGATTGTTGGTTTGAGCCG
AAATATGTATGGGAAATAAAAGCGGCCGATTTGAGCATTTCCCCCGATCA
CAGAGCTGCCGTTGGATTGGTCGATAAAGAGAAAGGAATAAGTTTGCGTT
TCCCGAGATTTATACGGATTAGGGAAGATAAGAAAGCCGAAAATGCTACA
ACTGCTCGACAGATTGCAGAAATGTATCGCAACCAGGATTCCATGAAAAC
CGGCGAATCCGCTATCAATCCCTATGAAGATGACGAATTTTACTGAAAAT
TATTACGTCTCTTATTATCAATTTATAATTGTAGTAAAATATATATATTT
TTTTTCATT
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protein sequence of SMED30010896-orf-1

>SMED30010896-orf-1 ID=SMED30010896-orf-1|Name=SMED30010896-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=782bp
MKQTSISQFFGSNTTKKNVEDISNKDKMGSTKIQKLEVKLKRKSDSPIKY
ENTDEVIAISKTKKRKTFLDSDSDSNDISIKKPNKKISNNLNDEIKALPK
KELNCIKTDDLNQTEIETVEKVNKIPSEYDPMINPYHIINDACWKPNEKI
PYLALAKTFEVIESTTKRLEITRTLSNFMRSVIYLSPKDLLPCVYLCLNK
VAPDYEGAELGVGEAVVKNALIQATDVDKKTIDSRMKKEGDLGLIAYNLP
SSQRYLVQPAKLTVPSVFQKLKIISGTSGKSSNTNKIDIIKNLLIASSKC
ERKYIVRSLLGKLRIRLAEQTVLAALGQAITLTPPNESKLDKSQNFDSLK
PIIDKNTAIIKTAFCQCPNYDLLIESLFKYGISNLPDHCSICPGVPIKPM
LAHPSKGVSEIFQRFDNSDFTCEYKYDGERAQIHVSTDANGKRKIQIFSR
NQENNTSKYPDIVKLIKEILENSSVESCIIDSEAVAWDRETKSILPFQKL
STRKKKDVNEVDIKIQVCLYAFDLIYFNDQSLVESSFRERRKILRENFTE
KPGFFVLATSLDSCNTDEISEFLEQSIKDKCEGLMIKTLDNDATYEISKR
SHNWLKLKKDYLDKMGDTVDLVVIGACYGTGKRANKYGTFLLACYDSESE
LFQTICRLGTGFTDEDLDNFYSELKETVTRKPVSSYDYEKSQIPDCWFEP
KYVWEIKAADLSISPDHRAAVGLVDKEKGISLRFPRFIRIREDKKAENAT
TARQIAEMYRNQDSMKTGESAINPYEDDEFY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002056medial muscle cell
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR036599DNA_ligase_N_sf
IPR000977DNA_ligase_ATP-dep
IPR012310DNA_ligase_ATP-dep_cent
IPR012340NA-bd_OB-fold
IPR012308DNA_ligase_ATP-dep_N
IPR012309DNA_ligase_ATP-dep_C
IPR016059DNA_ligase_ATP-dep_CS
Vocabulary: molecular function
TermDefinition
GO:0003910DNA ligase (ATP) activity
GO:0005524ATP binding
GO:0003677DNA binding
GO:0003909DNA ligase activity
GO:0000166nucleotide binding
GO:0016874ligase activity
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0006281DNA repair
GO:0006310DNA recombination
GO:0051103DNA ligation involved in DNA repair
GO:0006260DNA replication
GO:0006974cellular response to DNA damage stimulus
GO:0007049cell cycle
GO:0051301cell division
GO:0071897DNA biosynthetic process
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:2.40.50.140coord: 613..774
e-value: 4.7E-61
score: 207.5
NoneNo IPR availableGENE3DG3DSA:3.30.470.30coord: 428..558
e-value: 6.8E-76
score: 256.4
NoneNo IPR availableGENE3DG3DSA:3.30.1490.70coord: 409..612
e-value: 6.8E-76
score: 256.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 761..781
NoneNo IPR availablePANTHERPTHR45674FAMILY NOT NAMEDcoord: 37..770
NoneNo IPR availablePANTHERPTHR45674:SF4DNA LIGASE 1coord: 37..770
NoneNo IPR availableCDDcd07900Adenylation_DNA_ligase_I_Eukcoord: 388..611
e-value: 7.92867E-135
score: 396.156
NoneNo IPR availableCDDcd07969OBF_DNA_ligase_Icoord: 616..761
e-value: 9.69008E-87
score: 268.576
NoneNo IPR availableSUPERFAMILYSSF56091DNA ligase/mRNA capping enzyme, catalytic domaincoord: 392..613
IPR012309DNA ligase, ATP-dependent, C-terminalPFAMPF04679DNA_ligase_A_Ccoord: 634..744
e-value: 4.9E-25
score: 88.0
IPR036599DNA ligase, ATP-dependent, N-terminal domain superfamilyGENE3DG3DSA:1.10.3260.10coord: 126..401
e-value: 3.4E-102
score: 343.5
IPR036599DNA ligase, ATP-dependent, N-terminal domain superfamilySUPERFAMILYSSF117018ATP-dependent DNA ligase DNA-binding domaincoord: 128..389
IPR000977DNA ligase, ATP-dependentTIGRFAMTIGR00574TIGR00574coord: 209..760
e-value: 2.9E-164
score: 545.6
IPR012308DNA ligase, ATP-dependent, N-terminalPFAMPF04675DNA_ligase_A_Ncoord: 151..326
e-value: 7.4E-41
score: 140.3
IPR012310DNA ligase, ATP-dependent, centralPFAMPF01068DNA_ligase_A_Mcoord: 399..608
e-value: 7.3E-62
score: 208.6
IPR012310DNA ligase, ATP-dependent, centralPROSITEPS50160DNA_LIGASE_A3coord: 510..646
score: 43.925
IPR016059DNA ligase, ATP-dependent, conserved sitePROSITEPS00333DNA_LIGASE_A2coord: 582..608
IPR016059DNA ligase, ATP-dependent, conserved sitePROSITEPS00697DNA_LIGASE_A1coord: 423..431
IPR012340Nucleic acid-binding, OB-foldSUPERFAMILYSSF50249Nucleic acid-binding proteinscoord: 616..762