Lebercilin LCA5

Overview
NameLebercilin LCA5
Smed IDSMED30010778
Length (bp)1916
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Lebercilin LCA5 (SMED30010778) t-SNE clustered cells

Violin plots show distribution of expression levels for Lebercilin LCA5 (SMED30010778) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30010778

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
reproductive organSMED30010778h1SMcG0023095 Contig14281newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30010778h1SMcG0023095 Contig14281uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Human
Match: LCA5 (lebercilin LCA5 [Source:HGNC Symbol;Acc:HGNC:31923])

HSP 1 Score: 82.4185 bits (202), Expect = 5.393e-16
Identity = 61/210 (29.05%), Postives = 126/210 (60.00%), Query Frame = 3 
Query:  213 DTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKT 842
            DT+ ++++I+SA+LL++   +NE+  L+ +L  +  EN++L+   ++QE+ L + ++ +  I++LI +H  EI   K+++RK++      +   K+ E+E    K +L K KEI   + L ++ +L ++L  A   L  T+  +++    L+    +++ +LL  +K++    ++ + L+ ++  L   L+EKE+ L+I+NIYSNRL K+
Sbjct:   96 DTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKS 305
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Human
Match: LCA5 (lebercilin LCA5 [Source:HGNC Symbol;Acc:HGNC:31923])

HSP 1 Score: 82.8037 bits (203), Expect = 8.060e-16
Identity = 61/210 (29.05%), Postives = 126/210 (60.00%), Query Frame = 3 
Query:  213 DTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKT 842
            DT+ ++++I+SA+LL++   +NE+  L+ +L  +  EN++L+   ++QE+ L + ++ +  I++LI +H  EI   K+++RK++      +   K+ E+E    K +L K KEI   + L ++ +L ++L  A   L  T+  +++    L+    +++ +LL  +K++    ++ + L+ ++  L   L+EKE+ L+I+NIYSNRL K+
Sbjct:   96 DTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKS 305
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Human
Match: LCA5 (lebercilin LCA5 [Source:HGNC Symbol;Acc:HGNC:31923])

HSP 1 Score: 82.8037 bits (203), Expect = 8.060e-16
Identity = 61/210 (29.05%), Postives = 126/210 (60.00%), Query Frame = 3 
Query:  213 DTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKT 842
            DT+ ++++I+SA+LL++   +NE+  L+ +L  +  EN++L+   ++QE+ L + ++ +  I++LI +H  EI   K+++RK++      +   K+ E+E    K +L K KEI   + L ++ +L ++L  A   L  T+  +++    L+    +++ +LL  +K++    ++ + L+ ++  L   L+EKE+ L+I+NIYSNRL K+
Sbjct:   96 DTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKS 305
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Human
Match: LCA5L (lebercilin LCA5 like [Source:HGNC Symbol;Acc:HGNC:1255])

HSP 1 Score: 56.9954 bits (136), Expect = 8.454e-8
Identity = 51/208 (24.52%), Postives = 113/208 (54.33%), Query Frame = 3 
Query:  219 NSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSL-RKEAENESINLKTA--LNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRL 833
            ++M+ +I+SA+L ++   KNE+ ++  +LE I +EN+ L+    +  + + + +N   N+ +++ +H+ E++  +  +RK++     E++L RK  E +S  LKT   L   +++  +K L ++ EL  +L      +      +Q  + +L      +  +L    +++ +     + L+ ++  L   L+EK++ LEI+NIYS+R+
Sbjct:  137 DAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEK---ERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRI 341
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Human
Match: LCA5L (lebercilin LCA5 like [Source:HGNC Symbol;Acc:HGNC:1255])

HSP 1 Score: 56.9954 bits (136), Expect = 8.454e-8
Identity = 51/208 (24.52%), Postives = 113/208 (54.33%), Query Frame = 3 
Query:  219 NSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSL-RKEAENESINLKTA--LNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRL 833
            ++M+ +I+SA+L ++   KNE+ ++  +LE I +EN+ L+    +  + + + +N   N+ +++ +H+ E++  +  +RK++     E++L RK  E +S  LKT   L   +++  +K L ++ EL  +L      +      +Q  + +L      +  +L    +++ +     + L+ ++  L   L+EK++ LEI+NIYS+R+
Sbjct:  137 DAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEK---ERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRI 341
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Zebrafish
Match: lca5 (lebercilin LCA5 [Source:ZFIN;Acc:ZDB-GENE-090313-268])

HSP 1 Score: 74.3294 bits (181), Expect = 2.177e-13
Identity = 56/231 (24.24%), Postives = 135/231 (58.44%), Query Frame = 3 
Query:  183 KSSSKSTHIYDTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAK-TTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKTKLTRKCENAA 872
            +S SK     D + ++++++SA+LL++   KN +  L+   + +  ENR LR    +QE+ L + ++ D  I++L+ +H  E  + ++++R+++    T E+SLR E + +    ++ + K +++  ++ L ++ EL R+L      L  +++ +++ +  ++   G+++ +L N ++++    ++ + L+ ++  L   L+EKE+ L+ +NIY+NR++K    ++ EN +
Sbjct:  140 QSLSKDAPSKDVDQVTKRMLSARLLKINELKNALSELRLHADELQRENRLLRQLQLRQEKALHRYNDTDSEISQLLARHNNETHVLRERLRRSQENQRTAERSLR-ERDAQLQRCRSQMQKLQQLADDQNLGEREELSRKLIGTQSRLQDSEHRVKELEKNMELSSGSFQRQLANERRKTHDAQQEVKALQEEVERLCTKLKEKERELDARNIYANRMHKASSRKEAENGS 369
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Zebrafish
Match: lca5 (lebercilin LCA5 [Source:ZFIN;Acc:ZDB-GENE-090313-268])

HSP 1 Score: 72.7886 bits (177), Expect = 7.019e-13
Identity = 55/231 (23.81%), Postives = 135/231 (58.44%), Query Frame = 3 
Query:  183 KSSSKSTHIYDTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAK-TTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKTKLTRKCENAA 872
            +S SK     + + ++++++SA+LL++   KN +  L+   + +  ENR LR    +QE+ L + ++ D  I++L+ +H  E  + ++++R+++    T E+SLR E + +    ++ + K +++  ++ L ++ EL R+L      L  +++ +++ +  ++   G+++ +L N ++++    ++ + L+ ++  L   L+EKE+ L+ +NIY+NR++K    ++ EN +
Sbjct:  140 QSLSKDAPSKEVDQVTKRMLSARLLKINELKNALSELRLHADELQRENRLLRQLQLRQEKALHRYNDTDSEISQLLARHNNETHVLRERLRRSQENQRTAERSLR-ERDAQLQRCRSQMQKLQQLADDQNLGEREELSRKLIGTQSRLQDSEHRVKELEKNMELSSGSFQRQLANERRKTHDAQQEVKALQEEVERLCTKLKEKERELDARNIYANRMHKASSRKEAENGS 369
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Zebrafish
Match: lca5 (lebercilin LCA5 [Source:ZFIN;Acc:ZDB-GENE-090313-268])

HSP 1 Score: 72.4034 bits (176), Expect = 9.876e-13
Identity = 55/231 (23.81%), Postives = 135/231 (58.44%), Query Frame = 3 
Query:  183 KSSSKSTHIYDTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAK-TTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKTKLTRKCENAA 872
            +S SK     + + ++++++SA+LL++   KN +  L+   + +  ENR LR    +QE+ L + ++ D  I++L+ +H  E  + ++++R+++    T E+SLR E + +    ++ + K +++  ++ L ++ EL R+L      L  +++ +++ +  ++   G+++ +L N ++++    ++ + L+ ++  L   L+EKE+ L+ +NIY+NR++K    ++ EN +
Sbjct:  140 QSLSKDAPSKEVDQVTKRMLSARLLKINELKNALSELRLHADELQRENRLLRQLQLRQEKALHRYNDTDSEISQLLARHNNETHVLRERLRRSQENQRTAERSLR-ERDAQLQRCRSQMQKLQQLADDQNLGEREELSRKLIGTQSRLQDSEHRVKELEKNMELSSGSFQRQLANERRKTHDAQQEVKALQEEVERLCTKLKEKERELDARNIYANRMHKASSRKEAENGS 369
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Xenopus
Match: atg4d (autophagy related 4D, cysteine peptidase [Source:Xenbase;Acc:XB-GENE-1016717])

HSP 1 Score: 83.9593 bits (206), Expect = 2.734e-16
Identity = 56/209 (26.79%), Postives = 123/209 (58.85%), Query Frame = 3 
Query:  213 DTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNK 839
            D + ++++++SA+LL++   +NE+ + + +L+ + +EN+ L+   F+QE+ L + ++ +  I++LI +H  EI+  +D++RK++    + +   K+AE E       L K K++  N+ L ++ EL ++LD     L   +  ++  +  L+    +++ +LL+ KK++    E+ +  + ++  L   L+EKE+ L  +NIY+ RL+K
Sbjct:   77 DIDLVTKRVLSARLLKINELRNELTDHQTKLKELQNENKILKRLQFRQEKALTKFEDTENEISQLISRHNNEIRTLRDRLRKSQERERNMEKRLKDAEEELYRTNNTLKKLKQLSENRNLAEREELTKKLDIMESKLDEKERRVKDLEKNLELTQSSFQRQLLSEKKKAHDAQEENKTFQEELQRLTQKLKEKERELHAKNIYAYRLSK 285
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Xenopus
Match: atg4d (autophagy related 4D, cysteine peptidase [Source:Xenbase;Acc:XB-GENE-1016717])

HSP 1 Score: 83.5741 bits (205), Expect = 3.008e-16
Identity = 66/256 (25.78%), Postives = 142/256 (55.47%), Query Frame = 3 
Query:   72 SSFVISPGTPNKFLSCRINSTKNENELTRSRSQGNIGKSSSKSTHIYDTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNK 839
            ++F ++     + + C+    K E +    RSQ    +S SK     D + ++++++SA+LL++   +NE+ + + +L+ + +EN+ L+   F+QE+ L + ++ +  I++LI +H  EI+  +D++RK++    + +   K+AE E       L K K++  N+ L ++ EL ++LD     L   +  ++  +  L+    +++ +LL+ KK++    E+ +  + ++  L   L+EKE+ L  +NIY+ RL+K
Sbjct:   26 TTFFVASFLGLRKVGCKFPLNKKEGKWG-IRSQSLNKESPSK-----DIDLVTKRVLSARLLKINELRNELTDHQTKLKELQNENKILKRLQFRQEKALTKFEDTENEISQLISRHNNEIRTLRDRLRKSQERERNMEKRLKDAEEELYRTNNTLKKLKQLSENRNLAEREELTKKLDIMESKLDEKERRVKDLEKNLELTQSSFQRQLLSEKKKAHDAQEENKTFQEELQRLTQKLKEKERELHAKNIYAYRLSK 275
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Xenopus
Match: ENSXETT00000020390.1 (lebercilin-like [Source:NCBI gene;Acc:100497171])

HSP 1 Score: 83.5741 bits (205), Expect = 3.400e-16
Identity = 60/209 (28.71%), Postives = 124/209 (59.33%), Query Frame = 3 
Query:  213 DTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNK 839
            D   ++++++SA+LL++   +NEI+ L+ +LE    EN+ L+   F+QE+ L + ++ +  I++LI +H  E +  K+ +RK++    + +   KEAE+E     + + K K++  N+ L ++ EL ++LD     L   +  +Q  + KL+    +++ +L+  KK+ ++  E+ + L  ++  L   L+EKE+ L+++NIY+ RL+K
Sbjct:   49 DIALVTKRVLSARLLKINELRNEIRELQIKLEQHQKENKILKKLQFRQEKALNRFEDTESEISQLISRHNNETRALKEHLRKSQERERNTEKRLKEAEDELYRANSTVKKLKQLSENQHLGEREELAKKLDITETKLDEQERRVQDLEKKLEITQNSFQRQLMVEKKKIQNAQEENKMLLEELQKLTYKLKEKERELDVKNIYAYRLSK 257
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Xenopus
Match: atg4d (autophagy related 4D, cysteine peptidase [Source:Xenbase;Acc:XB-GENE-1016717])

HSP 1 Score: 82.4185 bits (202), Expect = 6.619e-16
Identity = 60/229 (26.20%), Postives = 132/229 (57.64%), Query Frame = 3 
Query:  162 RSQGNIG---KSSSKSTHIYDTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNK 839
            + +G  G   +S +K +   D + ++++++SA+LL++   +NE+ + + +L+ + +EN+ L+   F+QE+ L + ++ +  I++LI +H  EI+  +D++RK++    + +   K+AE E       L K K++  N+ L ++ EL ++LD     L   +  ++  +  L+    +++ +LL+ KK++    E+ +  + ++  L   L+EKE+ L  +NIY+ RL+K
Sbjct:   12 KKEGKWGIRSQSLNKESPSKDIDLVTKRVLSARLLKINELRNELTDHQTKLKELQNENKILKRLQFRQEKALTKFEDTENEISQLISRHNNEIRTLRDRLRKSQERERNMEKRLKDAEEELYRTNNTLKKLKQLSENRNLAEREELTKKLDIMESKLDEKERRVKDLEKNLELTQSSFQRQLLSEKKKAHDAQEENKTFQEELQRLTQKLKEKERELHAKNIYAYRLSK 240
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Xenopus
Match: ENSXETT00000034181.1 (lebercilin-like [Source:NCBI gene;Acc:100497171])

HSP 1 Score: 82.0333 bits (201), Expect = 1.106e-15
Identity = 66/238 (27.73%), Postives = 132/238 (55.46%), Query Frame = 3 
Query:  213 DTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKTKLTRKCE---------NAAPC---SNCT 890
            D   ++++++SA+LL++   +NEI+ L+ +LE    EN+ L+   F+QE+ L + ++ +  I++LI +H  E +  K+ +RK++    + +   KEAE+E     + + K K++  N+ L ++ EL ++LD     L   +  +Q  + KL+    +++ +L+  KK+ ++  E+ + L  ++  L   L+EKE+ L+++NIY+ RL+K    +  E         N +P     NCT
Sbjct:   46 DIALVTKRVLSARLLKINELRNEIRELQIKLEQHQKENKILKKLQFRQEKALNRFEDTESEISQLISRHNNETRALKEHLRKSQERERNTEKRLKEAEDELYRANSTVKKLKQLSENQHLGEREELAKKLDITETKLDEQERRVQDLEKKLEITQNSFQRQLMVEKKKIQNAQEENKMLLEELQKLTYKLKEKERELDVKNIYAYRLSKPSPKKDAEINPRWKGNPNYSPVFFSKNCT 283
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Mouse
Match: Lca5 (Leber congenital amaurosis 5 (human) [Source:MGI Symbol;Acc:MGI:1923032])

HSP 1 Score: 82.8037 bits (203), Expect = 2.389e-16
Identity = 59/210 (28.10%), Postives = 125/210 (59.52%), Query Frame = 3 
Query:  213 DTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKT 842
            D + ++++++SA+LL++   +NE+  L+ +L  +  EN+ L++  ++QE+ L + ++ +  I++LI +H  EI   K+++RK++      +   KE E E    K +L K K+I   + L ++ +L ++L  A   L  T+  +++    L+    +++ +LL  +K++    ++ + L+ ++  L+  L+EKEK L+I+NIY+NRL K+
Sbjct:   99 DPDIVTKRVLSARLLKINELQNEVSELQVKLAQLLKENKALKSLQYRQEKALNKFEDAENEISQLIHRHNNEITALKERLRKSQEKERATEKRVKETEGELFRTKFSLQKLKKISEARHLPERDDLAKKLVSAELKLDDTERKIKELSKNLELSTNSFQRQLLAERKRAFEAYDENKVLQKELQRLHHKLKEKEKELDIKNIYANRLPKS 308
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Mouse
Match: Lca5 (Leber congenital amaurosis 5 (human) [Source:MGI Symbol;Acc:MGI:1923032])

HSP 1 Score: 82.4185 bits (202), Expect = 3.719e-16
Identity = 59/210 (28.10%), Postives = 125/210 (59.52%), Query Frame = 3 
Query:  213 DTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKT 842
            D + ++++++SA+LL++   +NE+  L+ +L  +  EN+ L++  ++QE+ L + ++ +  I++LI +H  EI   K+++RK++      +   KE E E    K +L K K+I   + L ++ +L ++L  A   L  T+  +++    L+    +++ +LL  +K++    ++ + L+ ++  L+  L+EKEK L+I+NIY+NRL K+
Sbjct:   99 DPDIVTKRVLSARLLKINELQNEVSELQVKLAQLLKENKALKSLQYRQEKALNKFEDAENEISQLIHRHNNEITALKERLRKSQEKERATEKRVKETEGELFRTKFSLQKLKKISEARHLPERDDLAKKLVSAELKLDDTERKIKELSKNLELSTNSFQRQLLAERKRAFEAYDENKVLQKELQRLHHKLKEKEKELDIKNIYANRLPKS 308
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Mouse
Match: Lca5 (Leber congenital amaurosis 5 (human) [Source:MGI Symbol;Acc:MGI:1923032])

HSP 1 Score: 83.1889 bits (204), Expect = 3.744e-16
Identity = 59/210 (28.10%), Postives = 125/210 (59.52%), Query Frame = 3 
Query:  213 DTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKT 842
            D + ++++++SA+LL++   +NE+  L+ +L  +  EN+ L++  ++QE+ L + ++ +  I++LI +H  EI   K+++RK++      +   KE E E    K +L K K+I   + L ++ +L ++L  A   L  T+  +++    L+    +++ +LL  +K++    ++ + L+ ++  L+  L+EKEK L+I+NIY+NRL K+
Sbjct:   99 DPDIVTKRVLSARLLKINELQNEVSELQVKLAQLLKENKALKSLQYRQEKALNKFEDAENEISQLIHRHNNEITALKERLRKSQEKERATEKRVKETEGELFRTKFSLQKLKKISEARHLPERDDLAKKLVSAELKLDDTERKIKELSKNLELSTNSFQRQLLAERKRAFEAYDENKVLQKELQRLHHKLKEKEKELDIKNIYANRLPKS 308
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Mouse
Match: Lca5l (Leber congenital amaurosis 5-like [Source:MGI Symbol;Acc:MGI:3041157])

HSP 1 Score: 56.6102 bits (135), Expect = 8.441e-8
Identity = 45/205 (21.95%), Postives = 106/205 (51.71%), Query Frame = 3 
Query:  219 NSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRL 833
            ++M+ +I+SA+L ++   KNE+ ++  +LE    EN+ L+    +  + + +  N   N+ ++  +H+ E++  +  +RK++          +E + E +  K  L   + +  +K L ++ EL  +L +    +      +Q  + +L   + +Y  +L    +++ +     + L++++  L   L+EK++ LEI+NIY+NR+
Sbjct:  137 DTMTHRILSARLHKIKELKNELADVHRKLEASAIENQFLKQLQLRHLKAIGKYVNSQNNLPQITAKHQNEVKNLRQLLRKSQEKERAVSRKLRETDGELLRTKDVLQALQRLSEDKNLAEREELTDRLTDLTAKMEANDKKIQNLEKQLRLNNRSYSRQLAKENRKTLAAQTATKTLQAEVRQLQQKLKEKDRELEIKNIYTNRI 341
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Mouse
Match: Lca5l (Leber congenital amaurosis 5-like [Source:MGI Symbol;Acc:MGI:3041157])

HSP 1 Score: 56.6102 bits (135), Expect = 8.538e-8
Identity = 45/205 (21.95%), Postives = 106/205 (51.71%), Query Frame = 3 
Query:  219 NSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRL 833
            ++M+ +I+SA+L ++   KNE+ ++  +LE    EN+ L+    +  + + +  N   N+ ++  +H+ E++  +  +RK++          +E + E +  K  L   + +  +K L ++ EL  +L +    +      +Q  + +L   + +Y  +L    +++ +     + L++++  L   L+EK++ LEI+NIY+NR+
Sbjct:  142 DTMTHRILSARLHKIKELKNELADVHRKLEASAIENQFLKQLQLRHLKAIGKYVNSQNNLPQITAKHQNEVKNLRQLLRKSQEKERAVSRKLRETDGELLRTKDVLQALQRLSEDKNLAEREELTDRLTDLTAKMEANDKKIQNLEKQLRLNNRSYSRQLAKENRKTLAAQTATKTLQAEVRQLQQKLKEKDRELEIKNIYTNRI 346
[Close]
BLAST of Lebercilin LCA5 vs. UniProt/SwissProt
Match: sp|Q5U2Y9|LCA5_RAT (Lebercilin OS=Rattus norvegicus OX=10116 GN=Lca5 PE=2 SV=1)

HSP 1 Score: 86.2705 bits (212), Expect = 3.497e-16
Identity = 61/225 (27.11%), Postives = 132/225 (58.67%), Query Frame = 3 
Query:  213 DTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKTKLTRKCENAAPCSNC 887
            D + ++++++SA+LL++   +NE+  L+ +L  +  EN+ L++  ++QE+ L + ++ +  I++LI +H  EI   K+++RK++      +   K+ E E    K +L K K+I   + L ++ +L ++L  A   L  T+  +++    L+    +++ +LL  +K++    ++ + L+ ++  L+  L+EKEK L+I+NIY+NRL K+   ++ E A   ++C
Sbjct:  100 DPDIVTKRVLSARLLKITELQNEVSELQVKLAQLLKENKALKSLQYRQEKALSKFEDAENEISQLIHRHNGEITALKERLRKSQEKERMAEKRVKDTEGELFRTKFSLQKLKKISEARHLPERDDLAKKLVSAELKLDNTERKIKELSKNLELSTNSFQRQLLAERKRAFEAHDENKILQKELQRLHHKLKEKEKELDIKNIYANRLPKSSPKKEKEIARKHASC 324
[Close]
BLAST of Lebercilin LCA5 vs. UniProt/SwissProt
Match: sp|Q80ST9|LCA5_MOUSE (Lebercilin OS=Mus musculus OX=10090 GN=Lca5 PE=1 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 2.596e-15
Identity = 59/210 (28.10%), Postives = 125/210 (59.52%), Query Frame = 3 
Query:  213 DTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKT 842
            D + ++++++SA+LL++   +NE+  L+ +L  +  EN+ L++  ++QE+ L + ++ +  I++LI +H  EI   K+++RK++      +   KE E E    K +L K K+I   + L ++ +L ++L  A   L  T+  +++    L+    +++ +LL  +K++    ++ + L+ ++  L+  L+EKEK L+I+NIY+NRL K+
Sbjct:   99 DPDIVTKRVLSARLLKINELQNEVSELQVKLAQLLKENKALKSLQYRQEKALNKFEDAENEISQLIHRHNNEITALKERLRKSQEKERATEKRVKETEGELFRTKFSLQKLKKISEARHLPERDDLAKKLVSAELKLDDTERKIKELSKNLELSTNSFQRQLLAERKRAFEAYDENKVLQKELQRLHHKLKEKEKELDIKNIYANRLPKS 308
[Close]
BLAST of Lebercilin LCA5 vs. UniProt/SwissProt
Match: sp|Q86VQ0|LCA5_HUMAN (Lebercilin OS=Homo sapiens OX=9606 GN=LCA5 PE=1 SV=2)

HSP 1 Score: 82.8037 bits (203), Expect = 3.871e-15
Identity = 61/210 (29.05%), Postives = 126/210 (60.00%), Query Frame = 3 
Query:  213 DTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKT 842
            DT+ ++++I+SA+LL++   +NE+  L+ +L  +  EN++L+   ++QE+ L + ++ +  I++LI +H  EI   K+++RK++      +   K+ E+E    K +L K KEI   + L ++ +L ++L  A   L  T+  +++    L+    +++ +LL  +K++    ++ + L+ ++  L   L+EKE+ L+I+NIYSNRL K+
Sbjct:   96 DTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKS 305
[Close]
BLAST of Lebercilin LCA5 vs. UniProt/SwissProt
Match: sp|B0CM36|LCA5L_PAPAN (Lebercilin-like protein OS=Papio anubis OX=9555 GN=LCA5L PE=3 SV=1)

HSP 1 Score: 57.7658 bits (138), Expect = 2.550e-7
Identity = 47/206 (22.82%), Postives = 111/206 (53.88%), Query Frame = 3 
Query:  219 NSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAK-TTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRL 833
            ++M+ +I+SA+L ++   KNE+ ++  +LE I +EN+ L+    +  + + + +N   N+ +++ +H+ E++  +  +RK++    T  + LR E +++ +  K  L   +++  +K L ++ EL  +L      +      +Q  + +L      +  +L    +++ +     + L+ ++  L   L+EK++ LEI+NIYS+R+
Sbjct:  137 DAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTVSRKLR-ETDSQLLKTKDTLQALQKLSEDKNLAEREELTHKLSIITTKMEANDKKIQSLEKQLRLNSRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRI 341
[Close]
BLAST of Lebercilin LCA5 vs. UniProt/SwissProt
Match: sp|O95447|LCA5L_HUMAN (Lebercilin-like protein OS=Homo sapiens OX=9606 GN=LCA5L PE=1 SV=1)

HSP 1 Score: 56.9954 bits (136), Expect = 4.060e-7
Identity = 51/208 (24.52%), Postives = 113/208 (54.33%), Query Frame = 3 
Query:  219 NSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSL-RKEAENESINLKTA--LNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRL 833
            ++M+ +I+SA+L ++   KNE+ ++  +LE I +EN+ L+    +  + + + +N   N+ +++ +H+ E++  +  +RK++     E++L RK  E +S  LKT   L   +++  +K L ++ EL  +L      +      +Q  + +L      +  +L    +++ +     + L+ ++  L   L+EK++ LEI+NIYS+R+
Sbjct:  137 DAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEK---ERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRI 341
[Close]
BLAST of Lebercilin LCA5 vs. TrEMBL
Match: A0A401NKI7 (Lebercilin domain-containing protein OS=Scyliorhinus torazame OX=75743 GN=scyTo_0009326 PE=4 SV=1)

HSP 1 Score: 92.4337 bits (228), Expect = 8.940e-16
Identity = 71/263 (27.00%), Postives = 150/263 (57.03%), Query Frame = 3 
Query:  159 SRSQGNIGKSSSKSTHIYDTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKTKLTRKCENAAPCSNCTIRNKEKNLKSKSRTETKFL 947
            SR  G+  +S +K T   D + ++++++SA+LL++   +NE+  L+ +LE +  EN+ L+   ++QER L + ++ +  I+ LI +H  E+++ ++++RK++      +   K+ E E    +++L K K++  +K L+++ EL ++L +A   +  ++  L++ +  ++  + ++  ++ + +K++    E  + L+  I  LN  L+ KEK L+I+NIY+NRL K    +  E + P    T+ N  K ++    TE  FL
Sbjct:   79 SRRWGSRTQSLNKETVHKDVDLVTKRMLSARLLKINELRNEVTELQAKLEDLQKENKILKRLQYRQERALNKFEDTENEISLLITRHNDEVRVLRERLRKSQEKERAIEKQLKDTEEELYRTRSSLQKLKKLSEDKHLVERDELAQKLAKAEIKMEESERKLKELERNMELSNNSFLRQVTSERKKTHVAQENVQNLQETIQHLNQKLKGKEKELDIKNIYANRLIKASPKKDAE-SIPKKKATVPNTVKGVQ----TEEYFL 336
[Close]
BLAST of Lebercilin LCA5 vs. TrEMBL
Match: F7FYX1 (Lebercilin domain-containing protein OS=Ornithorhynchus anatinus OX=9258 PE=4 SV=2)

HSP 1 Score: 92.0485 bits (227), Expect = 1.591e-15
Identity = 67/254 (26.38%), Postives = 142/254 (55.91%), Query Frame = 3 
Query:   84 ISPG-TPNKFLSCRINSTKNENELTRSRSQGNIGKSSSKSTHIYDTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKT 842
             +PG +P  +   R  ST+      R    G   +S  +     D + ++++++SA+LLR+   ++++  L+ +L  +  ENR L+   ++QE+ L + ++ +  I++L+ +H  E++  ++Q+RK++      +   +EA+ E    + AL K K++   + L ++  L  +L  A   L  T+  +++    L+  + +++ +L + KK+++S  E+ E L+ ++  LN  L+EKE+ L+++NIYSNRL K+
Sbjct:   60 AAPGRSPGPYAVAR-KSTRRGPADGRGIRPGRRAQSLGREPPPKDVDLLARRVLSARLLRIGQLQSQVTELQVKLAELQKENRALKRLQYRQEKALNRFEDTENEISQLLARHGDEVKALREQLRKSQEKERATERRVREADCELYRTRRALRKLKKLAEARHLPERDRLATKLSAAEARLEDTERRIKEMAKNLELSNSSFQRQLHSEKKKTQSAQEENEALKLELQRLNQKLKEKERELDVKNIYSNRLAKS 312
[Close]
BLAST of Lebercilin LCA5 vs. TrEMBL
Match: A0A1L8G8W8 (Lebercilin domain-containing protein OS=Xenopus laevis OX=8355 GN=XELAEV_18027027mg PE=4 SV=1)

HSP 1 Score: 90.8929 bits (224), Expect = 3.105e-15
Identity = 67/229 (29.26%), Postives = 134/229 (58.52%), Query Frame = 3 
Query:  153 TRSRSQGNIGKSSSKSTHIYDTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNK 839
            +R    G   +S +K +   D   ++++++SA+LL++   +NEI +L+ +LE    EN+ L+   F+QE+ L + ++ +  I++LI +H  EI+  K+ +RK++    + +   KEAE+E     + L K K++  N+ L ++ EL ++LD A   L   +  +Q  + K +    +++ +L+  KK+ ++  E+ + L+ ++  L   L+EKE+ L+I+NIY+ RL+K
Sbjct:   85 SRKGKWGFRSQSLNKESRPKDIALVTKRVLSARLLKINELRNEITDLQIKLEHFQKENKILKKMQFRQEKALNKFEDTESEISQLISRHNNEIRALKEHLRKSQERERNTEKRLKEAEDELYRANSTLKKLKQLSENRHLGEREELAKKLDIAESKLDEQERRVQDLEKKTEISQNSFQRQLMVEKKKIQNAQEENKLLQEELQKLTYKLKEKERELDIKNIYAYRLSK 313
[Close]
BLAST of Lebercilin LCA5 vs. TrEMBL
Match: A0A1I8G3D1 (Lebercilin domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 89.3521 bits (220), Expect = 1.111e-14
Identity = 65/205 (31.71%), Postives = 118/205 (57.56%), Query Frame = 3 
Query:  219 NSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNL-LQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNR 830
            +  +++++SAK  ++   KNE++    +L  + +ENR L+ QN   ER L + DN+D  +++ I +H+ E++  K+Q+R+ K   +   +  K+ E E+  LK   ++ +E  S +GL D+  L +++ E LEN +  K   +Q  +  L++L  N++ E+     + K    K  ELE ++     AL+EKEK+L+IQNIY+ R
Sbjct:  154 DQATRRVMSAKNRKMAELKNELEFAMKELNELRTENRLLQKQNRINERALNKYDNEDSQLSQTIARHQEEVRTLKEQLRRYKDRCSEAGARNKDLEAENARLKKFNDRLREQASQEGLPDREALAKRVSE-LENDNAEKEKKIQDLERHLEHLQKNHRHEVAIEVHRHKETQRKVRELEEQLQEATTALKEKEKILDIQNIYAQR 357
[Close]
BLAST of Lebercilin LCA5 vs. TrEMBL
Match: A0A267F3R2 (Lebercilin domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig015184g1 PE=4 SV=1)

HSP 1 Score: 89.3521 bits (220), Expect = 1.211e-14
Identity = 65/205 (31.71%), Postives = 118/205 (57.56%), Query Frame = 3 
Query:  219 NSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNL-LQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNR 830
            +  +++++SAK  ++   KNE++    +L  + +ENR L+ QN   ER L + DN+D  +++ I +H+ E++  K+Q+R+ K   +   +  K+ E E+  LK   ++ +E  S +GL D+  L +++ E LEN +  K   +Q  +  L++L  N++ E+     + K    K  ELE ++     AL+EKEK+L+IQNIY+ R
Sbjct:  154 DQATRRVMSAKNRKMAELKNELEFAMKELNELRTENRLLQKQNRINERALNKYDNEDSQLSQTIARHQEEVRTLKEQLRRYKDRCSEAGARNKDLEAENARLKKFNDRLREQASQEGLPDREALAKRVSE-LENDNAEKEKKIQDLERHLEHLQKNHRHEVAIEVHRHKETQRKVRELEEQLQEATTALKEKEKILDIQNIYTQR 357
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Cavefish
Match: lca5 (lebercilin LCA5 [Source:NCBI gene;Acc:103033771])

HSP 1 Score: 79.337 bits (194), Expect = 6.479e-15
Identity = 56/236 (23.73%), Postives = 129/236 (54.66%), Query Frame = 3 
Query:  162 RSQGNIGKSSSKSTHIYDTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTT-ITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKTKLTRKCEN 866
            RS G   +S  K     D + ++++++SA+LL++   KN +  L+   + +  ENR LR    + E+ L +  + +  I++LI +H  E  + ++++R+++    T E+S R EA+ +    ++ L K +++  ++ L ++ EL R+L  A      +   +++ +  L+   G+++ +L   ++++   +++ + L  +   L+  L+ KE+ L+ +NIY+NR+ +    ++ EN
Sbjct:  144 RSSGMRSQSLGKDAPPKDLDLVTKRLLSARLLKISELKNALSELRTHADELQRENRLLRQLQLRHEKALHKYSDTESEISQLISRHNNETHVLRERLRRSQERERTAERSYR-EADAQLQRCRSQLQKLQQLADDQNLGERDELSRKLTHAQARAQESDRRVKELEKNLELSKGSFQRQLAGERRKTHDAMQEIQALREETEKLSAILKGKERELDARNIYANRITRAASKKEPEN 378
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Cavefish
Match: lca5 (lebercilin LCA5 [Source:NCBI gene;Acc:103033771])

HSP 1 Score: 79.337 bits (194), Expect = 6.479e-15
Identity = 56/236 (23.73%), Postives = 129/236 (54.66%), Query Frame = 3 
Query:  162 RSQGNIGKSSSKSTHIYDTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTT-ITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKTKLTRKCEN 866
            RS G   +S  K     D + ++++++SA+LL++   KN +  L+   + +  ENR LR    + E+ L +  + +  I++LI +H  E  + ++++R+++    T E+S R EA+ +    ++ L K +++  ++ L ++ EL R+L  A      +   +++ +  L+   G+++ +L   ++++   +++ + L  +   L+  L+ KE+ L+ +NIY+NR+ +    ++ EN
Sbjct:  144 RSSGMRSQSLGKDAPPKDLDLVTKRLLSARLLKISELKNALSELRTHADELQRENRLLRQLQLRHEKALHKYSDTESEISQLISRHNNETHVLRERLRRSQERERTAERSYR-EADAQLQRCRSQLQKLQQLADDQNLGERDELSRKLTHAQARAQESDRRVKELEKNLELSKGSFQRQLAGERRKTHDAMQEIQALREETEKLSAILKGKERELDARNIYANRITRAASKKEPEN 378
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010615.1 (pep scaffold:Pmarinus_7.0:GL477304:118413:123523:-1 gene:ENSPMAG00000009611.1 transcript:ENSPMAT00000010615.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 74.7146 bits (182), Expect = 1.552e-15
Identity = 50/206 (24.27%), Postives = 113/206 (54.85%), Query Frame = 3 
Query:  225 MSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKT 842
            +S+++ SA++      +NE+  L+ +L+  T ENR L+    +QE+ L + ++Q+ ++ +L+ +H AE +  ++ +R+A+          + A++E    +  L + + +   +GL ++ EL R L  A   L  ++  ++  +  LD    +Y+ +L   +++++    +   L+ +I  L   L++KE+ L+++NIY++RL K 
Sbjct:    4 VSRRVHSARVHAAVTLRNEVSELEARLDEATRENRALKQLQHRQEKALARFESQEGDLPQLLARHAAETRALREGLRRAREAERDAARRLRAAQDELATTREGLQRLQRLSEQRGLGEREELARSLARAETRLDESERRVKDLEKNLDLTTNSYQRQLAAERRKTQEAQAQVTALQEEIERLTQKLKDKERELDVKNIYASRLLKA 209
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Nematostella
Match: EDO32244 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVL7])

HSP 1 Score: 50.8322 bits (120), Expect = 1.895e-7
Identity = 38/146 (26.03%), Postives = 84/146 (57.53%), Query Frame = 3 
Query:  183 KSSSKSTHIYDTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAE----NESIN-LKTALNKSKEIISNKGLIDKAELRRQLD 605
            KS S  +     +++ Q+ +SA   R+    N ++ L+ +++ +  ENR L+  N +QER+L  +D ++  +  L+++H AE++  ++++++ K  +     +RKE E    +  IN L+  L+  K++ +NK L ++ +L ++L+
Sbjct:    1 KSLSADSQPLQVSTVVQRALSANRKRVTKLHNTVEELQQEVDDLRKENRMLKKVNMRQERDLRHVDQEEAALPMLLQRHSAEMRTLRERLKRNKQDL-----IRKEKEAHDHDAEINILRDKLSHFKQLANNKKLEEREKLAQRLE 141
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Medaka
Match: lca5 (lebercilin LCA5 [Source:NCBI gene;Acc:101164200])

HSP 1 Score: 76.6406 bits (187), Expect = 3.728e-14
Identity = 53/218 (24.31%), Postives = 122/218 (55.96%), Query Frame = 3 
Query:  189 SSKSTHIYDTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKT 842
            S +S+   D + ++++++SA+LL++   +N +  L+ ++E +  ENR L+    +QE+ L   D+ +  I+ L+ +H  EI + ++++R+ +      +   K+AE +    +  + + K+++  + L  + EL R+LDE        +  ++  +  L+  + +++ ++++ KK++    E+   L+ ++  L   L+EKE+ L+ +NIY+NRL K 
Sbjct:  160 SKESSPPKDLDLVTKRMLSARLLKINELRNALTELQQRMEDLKKENRVLKQLQVRQEKALRHYDDTESEISLLLSRHSNEIHVLRERLRRTQERERSSEQRLKDAEEQLQKSRATIARLKKLVDQRELGTRDELSRRLDEEKIRTQEAQQKIKDLERNLELTNSSFQRQIVSEKKKTVCAQEEVRTLQEELQRLTNKLKEKERDLDAKNIYANRLAKA 377
[Close]
BLAST of Lebercilin LCA5 vs. Ensembl Medaka
Match: lca5 (lebercilin LCA5 [Source:NCBI gene;Acc:101164200])

HSP 1 Score: 76.6406 bits (187), Expect = 3.728e-14
Identity = 53/218 (24.31%), Postives = 122/218 (55.96%), Query Frame = 3 
Query:  189 SSKSTHIYDTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKT 842
            S +S+   D + ++++++SA+LL++   +N +  L+ ++E +  ENR L+    +QE+ L   D+ +  I+ L+ +H  EI + ++++R+ +      +   K+AE +    +  + + K+++  + L  + EL R+LDE        +  ++  +  L+  + +++ ++++ KK++    E+   L+ ++  L   L+EKE+ L+ +NIY+NRL K 
Sbjct:  160 SKESSPPKDLDLVTKRMLSARLLKINELRNALTELQQRMEDLKKENRVLKQLQVRQEKALRHYDDTESEISLLLSRHSNEIHVLRERLRRTQERERSSEQRLKDAEEQLQKSRATIARLKKLVDQRELGTRDELSRRLDEEKIRTQEAQQKIKDLERNLELTNSSFQRQIVSEKKKTVCAQEEVRTLQEELQRLTNKLKEKERDLDAKNIYANRLAKA 377
[Close]
BLAST of Lebercilin LCA5 vs. Planmine SMEST
Match: SMESG000031296.1 (SMESG000031296.1)

HSP 1 Score: 1187.94 bits (3072), Expect = 0.000e+0
Identity = 594/597 (99.50%), Postives = 594/597 (99.50%), Query Frame = 3 
Query:   51 MSDSIKASSFVISPGTPNKFLSCRINSTKNENELTRSRSQGNIGKSSSKSTHIYDTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKTKLTRKCENAAPCSNCTIRNKEKNLKSKSRTETKFLSCFNKCDNFIKKNECSQQIVFHDKKDPVEFNRYKILEDIRKIISEEIKLGNLTIICNPVNSSNDQLLIPMIPSTIEKQVDSPFVDEDTGETEKSTIIAIEEPQENVLKTSKDIPRPSSVKQISIKNAIFQLQKEKNDLMRSKPKSKVRPYNPNSSQDKIETNGKVEPKLKYMYPNLDCIVSADDWWDDLETISVLNTVCDVNAKSSKVDNDKERVNCPDLLTHHEKPLQSIHLMYKLPKPIIEDLKNKEILKEKSFSNLISESRLNKVCVGNISHKNVTFQLPLTDFKKNEKFPQCSS 1841
            MSDSIKASSFVISPGTPNKFLSCRINSTKNENELTRSRSQGNIGKSSSKSTHIYDTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKTKLTRKCENAAPCSNCTIRNKEKNLKSKSRTETKFLSC NKCDNFIKKNECSQQIVFHDKKDPVEFNRYKILEDIRKIISEEIKLGNLTII NPVNSSNDQLLIPMIPSTIEKQVDSPFVDEDTGETEKSTIIAIEEPQENV KTSKDIPRPSSVKQISIKNAIFQLQKEKNDLMRSKPKSKVRPYNPNSSQDKIETNGKVEPKLKYMYPNLDCIVSADDWWDDLETISVLNTVCDVNAKSSKVDNDKERVNCPDLLTHHEKPLQSIHLMYKLPKPIIEDLKNKEILKEKSFSNLISESRLNKVCVGNISHKNVTFQLPLTDFKKNEKFPQCSS
Sbjct:    1 MSDSIKASSFVISPGTPNKFLSCRINSTKNENELTRSRSQGNIGKSSSKSTHIYDTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLNKTKLTRKCENAAPCSNCTIRNKEKNLKSKSRTETKFLSCINKCDNFIKKNECSQQIVFHDKKDPVEFNRYKILEDIRKIISEEIKLGNLTIIYNPVNSSNDQLLIPMIPSTIEKQVDSPFVDEDTGETEKSTIIAIEEPQENVSKTSKDIPRPSSVKQISIKNAIFQLQKEKNDLMRSKPKSKVRPYNPNSSQDKIETNGKVEPKLKYMYPNLDCIVSADDWWDDLETISVLNTVCDVNAKSSKVDNDKERVNCPDLLTHHEKPLQSIHLMYKLPKPIIEDLKNKEILKEKSFSNLISESRLNKVCVGNISHKNVTFQLPLTDFKKNEKFPQCSS 597
[Close]
BLAST of Lebercilin LCA5 vs. Planmine SMEST
Match: SMESG000022949.1 (SMESG000022949.1)

HSP 1 Score: 136.732 bits (343), Expect = 1.357e-33
Identity = 99/317 (31.23%), Postives = 181/317 (57.10%), Query Frame = 3 
Query:  228 SQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLN-KTKLTRKCENAAPCSNCTIRNKEKNLKSKSRTETKFLSCFNKCDNFIKKNECSQQIVFHDKKDPVEFNRY----KILEDIRKIISEEIKLGNLTIICNPVNSSNDQLLIPMIP 1163
            +Q+I+SA+  ++  Q N I  L+ Q++ +  EN+TL++Q ++Q++ L +ID++  +I K++EQH+AE+   K+Q+++ K  + +E   RKE+++E++ L+ +L K+ ++I  K L ++  L+ QL E  E L  ++  L+ T   L+ L+ ++K E+ N +KQ K Y  +C E E +++ + + L+EKEKLLEIQNIYS+R+    ++     +   CS C              T  + L   N  +N   K+  ++     ++ D    +RY    KI +DIR+I+ EEI  G +  I + +N  +     P++P
Sbjct:   81 AQRILSARKHKITDQNNLISELQKQIDDLLVENKTLKSQTYRQDKALSKIDSRQSDIPKILEQHQAEVTNLKEQLKRTKDLLNNEMKQRKESDSEALKLRNSLTKANQLIFEKNLGERNILQLQLVETQEKLESSEKSLEVTSKHLENLEKSHKREIYNLRKQLKQYEVQCRESEKELDLVKINLKEKEKLLEIQNIYSHRIKMPHRIPGSGSDRHACSTCL-----------GVTNDQLLDKLN-FNNLNGKSNPNKINYSSNQSDVSSNSRYLDPEKIKDDIRRILEEEILSGRIKPIESQMNYQS-----PVLP 380
[Close]
BLAST of Lebercilin LCA5 vs. Planmine SMEST
Match: SMESG000022949.1 (SMESG000022949.1)

HSP 1 Score: 136.732 bits (343), Expect = 1.802e-33
Identity = 130/453 (28.70%), Postives = 237/453 (52.32%), Query Frame = 3 
Query:  228 SQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRLN-KTKLTRKCENAAPCSNCTIRNKEKNLKSKSRTETKFLSCFNKCDNFIKKNECSQQIVFHDKKDPVEFNRY----KILEDIRKIISEEIKLGNLTIICNPVNSSNDQLLIPMIPSTIEKQVDSPFVD--------EDTGETEKSTIIAIEEPQENVLKTSKDIPRPSSVKQISIKNAIFQL---QKEKNDLMRSKPKSKVRPYNPN-SSQDKIETNGKVEPKLKYMYPNLDCIVSADDWWDDLETISVLN 1535
            +Q+I+SA+  ++  Q N I  L+ Q++ +  EN+TL++Q ++Q++ L +ID++  +I K++EQH+AE+   K+Q+++ K  + +E   RKE+++E++ L+ +L K+ ++I  K L ++  L+ QL E  E L  ++  L+ T   L+ L+ ++K E+ N +KQ K Y  +C E E +++ + + L+EKEKLLEIQNIYS+R+    ++     +   CS C              T  + L   N  +N   K+  ++     ++ D    +RY    KI +DIR+I+ EEI  G +  I + +N  +     P++P    +Q   P  +         +TG   +S I   +EPQ  +   +  +         ++K  + +    QK+K  L+     SK+   + + S+   IE+  K +  LKY YPN    V  D   +++ETI  ++
Sbjct:  117 AQRILSARKHKITDQNNLISELQKQIDDLLVENKTLKSQTYRQDKALSKIDSRQSDIPKILEQHQAEVTNLKEQLKRTKDLLNNEMKQRKESDSEALKLRNSLTKANQLIFEKNLGERNILQLQLVETQEKLESSEKSLEVTSKHLENLEKSHKREIYNLRKQLKQYEVQCRESEKELDLVKINLKEKEKLLEIQNIYSHRIKMPHRIPGSGSDRHACSTCL-----------GVTNDQLLDKLN-FNNLNGKSNPNKINYSSNQSDVSSNSRYLDPEKIKDDIRRILEEEILSGRIKPIESQMNYQS-----PVLPRDNIQQEREPSPELALSTHDSFNTGRAVESEIFD-KEPQTQIESVNDGVE--------NLKEDLEKFDRDQKQKQILL-----SKLSAIDQSKSTLTSIESTEKAD--LKYSYPNDKDFVENDLSINEIETIPAID 536
[Close]
BLAST of Lebercilin LCA5 vs. Planmine SMEST
Match: SMESG000004781.1 (SMESG000004781.1)

HSP 1 Score: 50.447 bits (119), Expect = 3.615e-6
Identity = 59/216 (27.31%), Postives = 118/216 (54.63%), Query Frame = 3 
Query:  216 TNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNFKQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKEAENESINLKTALNKSKEIISNKGLIDKAELRRQ---LDEALE-------NLSYTKNLLQKTQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKLLEIQNIYSNRL 833
            T   +Q+++ A  L +    +E  +L+ QL   ++E +T++ QN  QER L +++++D ++  +I ++ +E+   ++Q+R+ K  +   +  + + + E +  K  + K K +++++ L ++ +L ++   L+E+LE       +L  +  LL K  S    L+ N   EL       +SY E   EL++    +  +L+EK KLLE+QNIYS R+
Sbjct:  102 TAESTQKLLEASQLEINELISENADLRRQLLESSNELKTVQNQNKIQERYLNKVNSRDSDVPTIISRYNSELHSLQEQLRRKKEKLDTVERQKTDLDFELVKAKKKIEKLKALVADRQLQEREDLSKKIANLNESLEAEIKKNSDLERSMELLTKKYSYQMALETNKFKEL------KQSYTETLMELKN----IRSSLKEKNKLLEMQNIYSKRV 307
The following BLAST results are available for this feature:
BLAST of Lebercilin LCA5 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
LCA55.393e-1629.05lebercilin LCA5 [Source:HGNC Symbol;Acc:HGNC:31923... [more]
LCA58.060e-1629.05lebercilin LCA5 [Source:HGNC Symbol;Acc:HGNC:31923... [more]
LCA58.060e-1629.05lebercilin LCA5 [Source:HGNC Symbol;Acc:HGNC:31923... [more]
LCA5L8.454e-824.52lebercilin LCA5 like [Source:HGNC Symbol;Acc:HGNC:... [more]
LCA5L8.454e-824.52lebercilin LCA5 like [Source:HGNC Symbol;Acc:HGNC:... [more]
back to top
BLAST of Lebercilin LCA5 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Lebercilin LCA5 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Lebercilin LCA5 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
lca52.177e-1324.24lebercilin LCA5 [Source:ZFIN;Acc:ZDB-GENE-090313-2... [more]
lca57.019e-1323.81lebercilin LCA5 [Source:ZFIN;Acc:ZDB-GENE-090313-2... [more]
lca59.876e-1323.81lebercilin LCA5 [Source:ZFIN;Acc:ZDB-GENE-090313-2... [more]
back to top
BLAST of Lebercilin LCA5 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
atg4d2.734e-1626.79autophagy related 4D, cysteine peptidase [Source:X... [more]
atg4d3.008e-1625.78autophagy related 4D, cysteine peptidase [Source:X... [more]
ENSXETT00000020390.13.400e-1628.71lebercilin-like [Source:NCBI gene;Acc:100497171][more]
atg4d6.619e-1626.20autophagy related 4D, cysteine peptidase [Source:X... [more]
ENSXETT00000034181.11.106e-1527.73lebercilin-like [Source:NCBI gene;Acc:100497171][more]
back to top
BLAST of Lebercilin LCA5 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Lca52.389e-1628.10Leber congenital amaurosis 5 (human) [Source:MGI S... [more]
Lca53.719e-1628.10Leber congenital amaurosis 5 (human) [Source:MGI S... [more]
Lca53.744e-1628.10Leber congenital amaurosis 5 (human) [Source:MGI S... [more]
Lca5l8.441e-821.95Leber congenital amaurosis 5-like [Source:MGI Symb... [more]
Lca5l8.538e-821.95Leber congenital amaurosis 5-like [Source:MGI Symb... [more]
back to top
BLAST of Lebercilin LCA5 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5U2Y9|LCA5_RAT3.497e-1627.11Lebercilin OS=Rattus norvegicus OX=10116 GN=Lca5 P... [more]
sp|Q80ST9|LCA5_MOUSE2.596e-1528.10Lebercilin OS=Mus musculus OX=10090 GN=Lca5 PE=1 S... [more]
sp|Q86VQ0|LCA5_HUMAN3.871e-1529.05Lebercilin OS=Homo sapiens OX=9606 GN=LCA5 PE=1 SV... [more]
sp|B0CM36|LCA5L_PAPAN2.550e-722.82Lebercilin-like protein OS=Papio anubis OX=9555 GN... [more]
sp|O95447|LCA5L_HUMAN4.060e-724.52Lebercilin-like protein OS=Homo sapiens OX=9606 GN... [more]
back to top
BLAST of Lebercilin LCA5 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A401NKI78.940e-1627.00Lebercilin domain-containing protein OS=Scyliorhin... [more]
F7FYX11.591e-1526.38Lebercilin domain-containing protein OS=Ornithorhy... [more]
A0A1L8G8W83.105e-1529.26Lebercilin domain-containing protein OS=Xenopus la... [more]
A0A1I8G3D11.111e-1431.71Lebercilin domain-containing protein OS=Macrostomu... [more]
A0A267F3R21.211e-1431.71Lebercilin domain-containing protein OS=Macrostomu... [more]
back to top
BLAST of Lebercilin LCA5 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
lca56.479e-1523.73lebercilin LCA5 [Source:NCBI gene;Acc:103033771][more]
lca56.479e-1523.73lebercilin LCA5 [Source:NCBI gene;Acc:103033771][more]
back to top
BLAST of Lebercilin LCA5 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000010615.11.552e-1524.27pep scaffold:Pmarinus_7.0:GL477304:118413:123523:-... [more]
back to top
BLAST of Lebercilin LCA5 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Lebercilin LCA5 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO322441.895e-726.03Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Lebercilin LCA5 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
lca53.728e-1424.31lebercilin LCA5 [Source:NCBI gene;Acc:101164200][more]
lca53.728e-1424.31lebercilin LCA5 [Source:NCBI gene;Acc:101164200][more]
back to top
BLAST of Lebercilin LCA5 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000031296.10.000e+099.50SMESG000031296.1[more]
SMESG000022949.11.357e-3331.23SMESG000022949.1[more]
SMESG000022949.11.802e-3328.70SMESG000022949.1[more]
SMESG000004781.13.615e-627.31SMESG000004781.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010778 ID=SMED30010778|Name=Lebercilin LCA5|organism=Schmidtea mediterranea sexual|type=transcript|length=1916bp
TTCCGATCTAATATCCTCCATAATAATTATTATTAAGCAAGGCATAAAAA
ATGAGTGATAGTATTAAGGCATCCTCATTTGTCATTTCCCCCGGAACGCC
CAATAAATTTTTATCATGCAGAATCAATAGTACGAAAAATGAGAATGAAC
TCACCAGATCTAGATCCCAAGGAAACATTGGGAAATCCTCATCCAAATCC
ACTCATATCTATGATACCAATTCGATGTCCCAACAGATTATATCAGCAAA
ACTTCTACGTTTGCCAATGCAAAAGAATGAAATTCAAAACTTAAAGGGTC
AGCTGGAAATCATAACTTCAGAAAACCGAACCCTTCGAACTCAAAATTTT
AAACAAGAACGAGAACTAATTCAAATTGATAATCAAGACTTGAATATCAC
AAAATTAATCGAGCAGCACGAAGCGGAGATTCAAATCTTCAAGGACCAAA
TACGCAAAGCCAAAACAACGATCACTCATGAGCAAAGTCTTAGAAAGGAA
GCTGAAAATGAATCAATAAACTTAAAAACAGCTCTTAATAAAAGTAAAGA
AATCATATCCAACAAGGGATTAATTGATAAGGCAGAGTTGAGAAGACAGC
TTGACGAAGCTTTAGAAAACCTTAGTTATACGAAAAATCTACTTCAAAAA
ACTCAAAGCAAATTGGATTATTTGGACGGAAACTATAAAGTTGAGTTACT
GAACTGTAAAAAGCAATCTAAATCATATTTGGAAAAATGTGAAGAGTTGG
AATCAAAAATTAATTTCCTTAATGTTGCTTTAAGGGAAAAAGAAAAATTA
TTAGAAATTCAAAACATATATTCAAATCGGTTAAATAAAACAAAATTGAC
AAGAAAATGTGAAAATGCTGCTCCTTGTTCAAACTGTACAATTAGAAATA
AAGAAAAAAATTTAAAATCCAAATCCCGCACGGAAACCAAATTTTTATCT
TGTTTTAATAAATGTGACAACTTTATAAAGAAAAACGAATGTTCTCAGCA
AATTGTTTTTCATGATAAAAAGGATCCTGTGGAGTTTAATCGTTATAAAA
TTTTAGAGGATATTCGAAAGATAATCAGTGAAGAAATAAAACTTGGAAAT
CTTACAATAATATGTAATCCAGTTAACTCAAGCAATGATCAACTACTCAT
TCCGATGATCCCTTCTACTATTGAAAAACAGGTTGACAGTCCATTTGTCG
ACGAAGACACCGGGGAAACTGAAAAGTCGACAATAATAGCAATTGAAGAA
CCCCAAGAAAATGTTTTAAAAACGTCAAAAGATATTCCGAGACCTTCCTC
TGTCAAACAAATCAGCATTAAGAATGCTATATTTCAATTACAAAAAGAAA
AGAACGACTTAATGAGATCCAAACCAAAATCCAAAGTTAGACCTTATAAT
CCAAATTCTTCTCAAGATAAGATTGAAACAAATGGAAAAGTTGAACCTAA
ATTGAAATACATGTACCCAAATCTTGATTGTATTGTTTCCGCTGACGACT
GGTGGGATGACCTTGAAACCATAAGTGTATTAAATACAGTTTGTGATGTT
AACGCCAAATCATCTAAAGTAGACAATGATAAGGAAAGGGTGAATTGCCC
CGATTTACTTACCCACCATGAGAAACCATTACAATCCATTCATCTCATGT
ATAAACTACCAAAGCCGATTATTGAAGATCTGAAAAATAAAGAAATATTG
AAGGAAAAATCGTTTTCCAATTTAATAAGTGAATCAAGATTAAATAAAGT
CTGCGTTGGGAATATCAGTCATAAAAATGTGACTTTCCAACTACCTCTAA
CCGATTTTAAGAAGAACGAAAAGTTTCCACAGTGCAGTTCTTAAGTTGGT
ATTTGTTGAAAAATAGAAAAAACAAGGGTTAAAAATAGTGAATGACTGAA
ATTGTCTTCGTAGATT
back to top

protein sequence of SMED30010778-orf-1

>SMED30010778-orf-1 ID=SMED30010778-orf-1|Name=SMED30010778-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=598bp
MSDSIKASSFVISPGTPNKFLSCRINSTKNENELTRSRSQGNIGKSSSKS
THIYDTNSMSQQIISAKLLRLPMQKNEIQNLKGQLEIITSENRTLRTQNF
KQERELIQIDNQDLNITKLIEQHEAEIQIFKDQIRKAKTTITHEQSLRKE
AENESINLKTALNKSKEIISNKGLIDKAELRRQLDEALENLSYTKNLLQK
TQSKLDYLDGNYKVELLNCKKQSKSYLEKCEELESKINFLNVALREKEKL
LEIQNIYSNRLNKTKLTRKCENAAPCSNCTIRNKEKNLKSKSRTETKFLS
CFNKCDNFIKKNECSQQIVFHDKKDPVEFNRYKILEDIRKIISEEIKLGN
LTIICNPVNSSNDQLLIPMIPSTIEKQVDSPFVDEDTGETEKSTIIAIEE
PQENVLKTSKDIPRPSSVKQISIKNAIFQLQKEKNDLMRSKPKSKVRPYN
PNSSQDKIETNGKVEPKLKYMYPNLDCIVSADDWWDDLETISVLNTVCDV
NAKSSKVDNDKERVNCPDLLTHHEKPLQSIHLMYKLPKPIIEDLKNKEIL
KEKSFSNLISESRLNKVCVGNISHKNVTFQLPLTDFKKNEKFPQCSS*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0032391photoreceptor connecting cilium
GO:0005737cytoplasm
GO:0005856cytoskeleton
GO:0005929cilium
GO:0042995cell projection
Vocabulary: molecular function
TermDefinition
GO:0044877macromolecular complex binding
GO:0032403protein complex binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR026188Lebercilin-like
IPR028933Lebercilin_dom
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0015031protein transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 120..168
NoneNo IPR availableCOILSCoilCoilcoord: 177..197
NoneNo IPR availableCOILSCoilCoilcoord: 78..98
NoneNo IPR availableCOILSCoilCoilcoord: 216..250
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 31..54
NoneNo IPR availablePANTHERPTHR16650:SF6coord: 46..289
IPR028933Lebercilin domainPFAMPF15619Lebercilincoord: 60..250
e-value: 1.4E-25
score: 90.1
IPR026188Lebercilin-likePANTHERPTHR16650C21ORF13-RELATEDcoord: 46..289