Lysosomal-associated transmembrane protein 4A
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30010777 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Human
Match: QDPR (quinoid dihydropteridine reductase [Source:HGNC Symbol;Acc:HGNC:9752]) HSP 1 Score: 70.8626 bits (172), Expect = 1.558e-13 Identity = 33/69 (47.83%), Postives = 40/69 (57.97%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 MP + +LP TLDT NR SMP DF SWTP+ F+ ETF WI G RP +G I T G T++ Sbjct: 140 MPPGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGKNRPSSGSLIQVVTTEGRTEL 208
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Human
Match: QDPR (quinoid dihydropteridine reductase [Source:HGNC Symbol;Acc:HGNC:9752]) HSP 1 Score: 70.8626 bits (172), Expect = 2.682e-13 Identity = 33/69 (47.83%), Postives = 40/69 (57.97%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 MP + +LP TLDT NR SMP DF SWTP+ F+ ETF WI G RP +G I T G T++ Sbjct: 171 MPPGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGKNRPSSGSLIQVVTTEGRTEL 239
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Celegans
Match: qdpr-1 (Quinoid DihydroPteridine Reductase [Source:UniProtKB/TrEMBL;Acc:Q9XVJ3]) HSP 1 Score: 69.3218 bits (168), Expect = 3.101e-13 Identity = 34/70 (48.57%), Postives = 44/70 (62.86%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKW-IEGTERPKNGDFIYFNTKNGETKI 1308 +P NS TI+P TLDT NR MPN D SWTP+SF+SE +KW E + RP +G + T+NG + I Sbjct: 164 LPDNSAVLTIMPVTLDTPMNRKWMPNADHSSWTPLSFISEHLLKWTTETSSRPSSGALLKITTENGTSTI 233
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Fly
Match: Dhpr (gene:FBgn0035964 transcript:FBtr0076531) HSP 1 Score: 70.0922 bits (170), Expect = 2.097e-13 Identity = 31/69 (44.93%), Postives = 44/69 (63.77%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 +P S+ +ILP TLDT NR MP+ DF +WTP++ V+ F+KW + ERPK G + T NG T++ Sbjct: 163 LPAGSLAVSILPVTLDTPMNRKWMPDADFGTWTPLTEVAGLFLKWTQDQERPKTGSLLQLITTNGITQL 231
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Fly
Match: Dhpr (gene:FBgn0035964 transcript:FBtr0100531) HSP 1 Score: 70.0922 bits (170), Expect = 2.097e-13 Identity = 31/69 (44.93%), Postives = 44/69 (63.77%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 +P S+ +ILP TLDT NR MP+ DF +WTP++ V+ F+KW + ERPK G + T NG T++ Sbjct: 163 LPAGSLAVSILPVTLDTPMNRKWMPDADFGTWTPLTEVAGLFLKWTQDQERPKTGSLLQLITTNGITQL 231
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Fly
Match: Dhpr (gene:FBgn0035964 transcript:FBtr0100532) HSP 1 Score: 70.0922 bits (170), Expect = 2.097e-13 Identity = 31/69 (44.93%), Postives = 44/69 (63.77%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 +P S+ +ILP TLDT NR MP+ DF +WTP++ V+ F+KW + ERPK G + T NG T++ Sbjct: 163 LPAGSLAVSILPVTLDTPMNRKWMPDADFGTWTPLTEVAGLFLKWTQDQERPKTGSLLQLITTNGITQL 231
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Zebrafish
Match: qdpra (quinoid dihydropteridine reductase a [Source:ZFIN;Acc:ZDB-GENE-070705-197]) HSP 1 Score: 71.633 bits (174), Expect = 8.546e-14 Identity = 30/68 (44.12%), Postives = 42/68 (61.76%), Query Frame = -1 Query: 1105 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETK 1308 +P ++ ILP TLDT NR MP+ DF SWTP+ +++ETF W G+ RP +G I T G+T+ Sbjct: 165 LPSGAVAVAILPVTLDTPMNRKFMPDADFGSWTPLEYIAETFHSWATGSGRPASGSLIQLETTGGKTE 232
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Zebrafish
Match: qdprb2 (quinoid dihydropteridine reductase b2 [Source:ZFIN;Acc:ZDB-GENE-070720-19]) HSP 1 Score: 69.3218 bits (168), Expect = 7.201e-13 Identity = 31/67 (46.27%), Postives = 40/67 (59.70%), Query Frame = -1 Query: 1108 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGET 1308 +P S+ ILP+TLDT NR MPN D SWTP++ V++ F KW G RP +G + T NG T Sbjct: 183 LPPRSVALAILPETLDTPTNRRIMPNADVSSWTPLNHVTQLFFKWTVGESRPPSGSLVELVTANGRT 249
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Zebrafish
Match: BX005473.1 (quinoid dihydropteridine reductase b2 [Source:NCBI gene;Acc:101887190]) HSP 1 Score: 68.5514 bits (166), Expect = 8.796e-13 Identity = 31/67 (46.27%), Postives = 39/67 (58.21%), Query Frame = -1 Query: 1108 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGET 1308 +P S+ ILP TLDT NR MPN D SWTP++ V++ F KW G RP +G + T NG T Sbjct: 166 LPPRSVALAILPVTLDTPTNRRIMPNADVSSWTPLNHVTQLFFKWTVGESRPASGSLVELVTANGRT 232
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Zebrafish
Match: BX005473.1 (quinoid dihydropteridine reductase b2 [Source:NCBI gene;Acc:101887190]) HSP 1 Score: 68.9366 bits (167), Expect = 8.965e-13 Identity = 31/67 (46.27%), Postives = 39/67 (58.21%), Query Frame = -1 Query: 1108 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGET 1308 +P S+ ILP TLDT NR MPN D SWTP++ V++ F KW G RP +G + T NG T Sbjct: 170 LPPRSVALAILPVTLDTPTNRRIMPNADVSSWTPLNHVTQLFFKWTVGESRPASGSLVELVTANGRT 236
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Zebrafish
Match: BX005473.1 (quinoid dihydropteridine reductase b2 [Source:NCBI gene;Acc:101887190]) HSP 1 Score: 68.5514 bits (166), Expect = 9.802e-13 Identity = 31/67 (46.27%), Postives = 39/67 (58.21%), Query Frame = -1 Query: 1108 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGET 1308 +P S+ ILP TLDT NR MPN D SWTP++ V++ F KW G RP +G + T NG T Sbjct: 171 LPPRSVALAILPVTLDTPTNRRIMPNADVSSWTPLNHVTQLFFKWTVGESRPASGSLVELVTANGRT 237
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Xenopus
Match: ifrd2 (interferon-related developmental regulator 2 [Source:Xenbase;Acc:XB-GENE-1003246]) HSP 1 Score: 78.1814 bits (191), Expect = 6.996e-16 Identity = 33/69 (47.83%), Postives = 45/69 (65.22%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 MP S ILP TLDT NR+SMP+ D+ WTP+ F++ETF WI G RP++G I T+ G+T++ Sbjct: 168 MPAKSAAVAILPVTLDTPANRASMPDADYTCWTPLDFIAETFYNWITGQNRPQSGSLIEVITEKGKTEL 236
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Mouse
Match: Qdpr (quinoid dihydropteridine reductase [Source:MGI Symbol;Acc:MGI:97836]) HSP 1 Score: 72.0182 bits (175), Expect = 8.654e-15 Identity = 33/69 (47.83%), Postives = 43/69 (62.32%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 MP + +LP TLDT NR SMP DF SWTP+ F+ ETF WI G +RP +G I T +G+T++ Sbjct: 66 MPPGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGNKRPNSGSLIQVVTTDGKTEL 134
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Mouse
Match: Qdpr (quinoid dihydropteridine reductase [Source:MGI Symbol;Acc:MGI:97836]) HSP 1 Score: 72.0182 bits (175), Expect = 2.857e-14 Identity = 33/69 (47.83%), Postives = 43/69 (62.32%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 MP + +LP TLDT NR SMP DF SWTP+ F+ ETF WI G +RP +G I T +G+T++ Sbjct: 116 MPPGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGNKRPNSGSLIQVVTTDGKTEL 184
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Mouse
Match: Qdpr (quinoid dihydropteridine reductase [Source:MGI Symbol;Acc:MGI:97836]) HSP 1 Score: 72.0182 bits (175), Expect = 2.857e-14 Identity = 33/69 (47.83%), Postives = 43/69 (62.32%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 MP + +LP TLDT NR SMP DF SWTP+ F+ ETF WI G +RP +G I T +G+T++ Sbjct: 116 MPPGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGNKRPNSGSLIQVVTTDGKTEL 184
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Mouse
Match: Qdpr (quinoid dihydropteridine reductase [Source:MGI Symbol;Acc:MGI:97836]) HSP 1 Score: 72.0182 bits (175), Expect = 2.857e-14 Identity = 33/69 (47.83%), Postives = 43/69 (62.32%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 MP + +LP TLDT NR SMP DF SWTP+ F+ ETF WI G +RP +G I T +G+T++ Sbjct: 116 MPPGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGNKRPNSGSLIQVVTTDGKTEL 184
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Mouse
Match: Qdpr (quinoid dihydropteridine reductase [Source:MGI Symbol;Acc:MGI:97836]) HSP 1 Score: 72.4034 bits (176), Expect = 5.769e-14 Identity = 33/69 (47.83%), Postives = 43/69 (62.32%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 MP + +LP TLDT NR SMP DF SWTP+ F+ ETF WI G +RP +G I T +G+T++ Sbjct: 168 MPPGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGNKRPNSGSLIQVVTTDGKTEL 236
BLAST of Lysosomal-associated transmembrane protein 4A vs. UniProt/SwissProt
Match: sp|P11348|DHPR_RAT (Dihydropteridine reductase OS=Rattus norvegicus OX=10116 GN=Qdpr PE=1 SV=1) HSP 1 Score: 72.7886 bits (177), Expect = 2.489e-13 Identity = 33/69 (47.83%), Postives = 43/69 (62.32%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 MP + +LP TLDT NR SMP DF SWTP+ F+ ETF WI G +RP +G I T +G+T++ Sbjct: 168 MPSGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGNKRPNSGSLIQVVTTDGKTEL 236
BLAST of Lysosomal-associated transmembrane protein 4A vs. UniProt/SwissProt
Match: sp|Q8BVI4|DHPR_MOUSE (Dihydropteridine reductase OS=Mus musculus OX=10090 GN=Qdpr PE=1 SV=2) HSP 1 Score: 72.4034 bits (176), Expect = 4.036e-13 Identity = 33/69 (47.83%), Postives = 43/69 (62.32%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 MP + +LP TLDT NR SMP DF SWTP+ F+ ETF WI G +RP +G I T +G+T++ Sbjct: 168 MPPGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGNKRPNSGSLIQVVTTDGKTEL 236
BLAST of Lysosomal-associated transmembrane protein 4A vs. UniProt/SwissProt
Match: sp|P09417|DHPR_HUMAN (Dihydropteridine reductase OS=Homo sapiens OX=9606 GN=QDPR PE=1 SV=2) HSP 1 Score: 70.8626 bits (172), Expect = 1.288e-12 Identity = 33/69 (47.83%), Postives = 40/69 (57.97%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 MP + +LP TLDT NR SMP DF SWTP+ F+ ETF WI G RP +G I T G T++ Sbjct: 171 MPPGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGKNRPSSGSLIQVVTTEGRTEL 239
BLAST of Lysosomal-associated transmembrane protein 4A vs. UniProt/SwissProt
Match: sp|Q8MJ30|DHPR_PIG (Dihydropteridine reductase OS=Sus scrofa OX=9823 GN=QDPR PE=2 SV=1) HSP 1 Score: 68.5514 bits (166), Expect = 7.195e-12 Identity = 32/69 (46.38%), Postives = 41/69 (59.42%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 MP + +LP TLDT NR SMP+ DF SWTP+ F+ ETF WI RP +G I T G+T++ Sbjct: 170 MPSGAAAIAVLPVTLDTPLNRKSMPHADFSSWTPLEFLVETFHDWIIEKNRPSSGSLIQVVTTQGKTEL 238
BLAST of Lysosomal-associated transmembrane protein 4A vs. UniProt/SwissProt
Match: sp|Q3T0Z7|DHPR_BOVIN (Dihydropteridine reductase OS=Bos taurus OX=9913 GN=QDPR PE=2 SV=1) HSP 1 Score: 67.0106 bits (162), Expect = 2.503e-11 Identity = 31/69 (44.93%), Postives = 40/69 (57.97%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 +P + +LP TLDT NR SMP DF SWTP+ F+ ETF WI RP +G I T G+T++ Sbjct: 169 LPPGAAAVALLPVTLDTPVNRKSMPEADFSSWTPLEFLVETFHDWITEKNRPSSGSLIQVVTTEGKTEL 237
BLAST of Lysosomal-associated transmembrane protein 4A vs. TrEMBL
Match: Q52KN0 (MGC115198 protein OS=Xenopus laevis OX=8355 GN=qdpr PE=2 SV=1) HSP 1 Score: 82.4185 bits (202), Expect = 4.252e-14 Identity = 35/69 (50.72%), Postives = 47/69 (68.12%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 MP+NS ILP TLDT NR+SMP+ D+ SWTP+ F++ETF WI G RP++G I T+ G T++ Sbjct: 168 MPVNSAAVAILPVTLDTPANRASMPDADYTSWTPLDFIAETFYNWINGQNRPQSGSLIEVKTQKGITEL 236
BLAST of Lysosomal-associated transmembrane protein 4A vs. TrEMBL
Match: A0A0M4EAY3 (Dhpr OS=Drosophila busckii OX=30019 GN=Dbus_chr3Lg1657 PE=4 SV=1) HSP 1 Score: 81.2629 bits (199), Expect = 9.264e-14 Identity = 36/69 (52.17%), Postives = 48/69 (69.57%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 +P +++ +ILP TLDT NR MPNGDF +WTP+SFV+E F KWI+ ERPK G + T NG T++ Sbjct: 163 LPNDALVVSILPVTLDTPMNRKWMPNGDFGTWTPLSFVAELFCKWIKAEERPKTGALLQLITTNGVTEL 231
BLAST of Lysosomal-associated transmembrane protein 4A vs. TrEMBL
Match: A0A067QT37 (Dihydropteridine reductase OS=Zootermopsis nevadensis OX=136037 GN=L798_01556 PE=4 SV=1) HSP 1 Score: 80.4925 bits (197), Expect = 1.726e-13 Identity = 35/69 (50.72%), Postives = 47/69 (68.12%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 +P NS++ ILP TLDT NR MPN DF +WTP+ FV+E F++W G ERP NG ++ TKN T++ Sbjct: 166 LPPNSLSVAILPVTLDTPMNRKWMPNADFSTWTPLEFVAELFLRWSRGEERPPNGSLVHLVTKNYTTEL 234
BLAST of Lysosomal-associated transmembrane protein 4A vs. TrEMBL
Match: S4NX17 (Dihydropteridine reductase OS=Pararge aegeria OX=116150 PE=4 SV=1) HSP 1 Score: 75.8702 bits (185), Expect = 3.260e-13 Identity = 34/69 (49.28%), Postives = 46/69 (66.67%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 +P NS+ ILP TLDT+ NR MP DF SWTP++FV+E F KW++G ERP +G + TK+ T + Sbjct: 25 LPENSLAVAILPVTLDTEMNRKWMPKADFGSWTPLTFVAELFGKWLKGEERPPSGSLVALVTKDNITDL 93
BLAST of Lysosomal-associated transmembrane protein 4A vs. TrEMBL
Match: A0A194QYW2 (Dihydropteridine reductase OS=Papilio machaon OX=76193 GN=RR48_09613 PE=4 SV=1) HSP 1 Score: 79.7221 bits (195), Expect = 3.268e-13 Identity = 34/69 (49.28%), Postives = 47/69 (68.12%), Query Frame = -1 Query: 1102 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKI 1308 +P NS+ I+P TLDT+ NR MP DF +WTP+SFV++ F KWI+G ERP +G + TKN T++ Sbjct: 163 LPENSLAVAIMPVTLDTEMNRKWMPKADFSTWTPLSFVAQLFDKWIKGEERPASGSLVALVTKNNVTEL 231
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Cavefish
Match: qdpra (dihydropteridine reductase-like [Source:NCBI gene;Acc:103021866]) HSP 1 Score: 71.633 bits (174), Expect = 7.611e-14 Identity = 30/68 (44.12%), Postives = 41/68 (60.29%), Query Frame = -1 Query: 1105 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETK 1308 +P S+ ILP TLDT NR MP+ DF SWTP+ ++++TF W G+ RP +G I T G T+ Sbjct: 167 LPAGSVAVAILPVTLDTPMNRKFMPDADFSSWTPLEYIAQTFYSWATGSGRPASGSLIQLVTAGGVTE 234
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Cavefish
Match: zgc:171517 (dihydropteridine reductase [Source:NCBI gene;Acc:103041363]) HSP 1 Score: 63.5438 bits (153), Expect = 3.869e-11 Identity = 27/68 (39.71%), Postives = 39/68 (57.35%), Query Frame = -1 Query: 1105 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETK 1308 +P + ILP TLDT NR MP+ D +WTP+ +V+E KW G ERP +G + T + +T+ Sbjct: 165 LPAGASAIAILPVTLDTPMNRQFMPDADVSAWTPLEYVAELLYKWAVGEERPASGSLVQLVTTDSKTE 232
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Cavefish
Match: qdpra (dihydropteridine reductase-like [Source:NCBI gene;Acc:103021866]) HSP 1 Score: 49.2914 bits (116), Expect = 2.973e-6 Identity = 20/42 (47.62%), Postives = 28/42 (66.67%), Query Frame = -1 Query: 1183 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETF 1308 +P S+ ILP TLDT NR MP+ DF SWTP+ ++++ F Sbjct: 167 LPAGSVAVAILPVTLDTPMNRKFMPDADFSSWTPLEYIAQYF 208
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Sea Lamprey
Match: qdpra (quinoid dihydropteridine reductase a [Source:ZFIN;Acc:ZDB-GENE-070705-197]) HSP 1 Score: 67.0106 bits (162), Expect = 5.337e-13 Identity = 28/58 (48.28%), Postives = 39/58 (67.24%), Query Frame = -1 Query: 1096 TLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKINT 1269 TLDT NR SMPN D +WTP+ FV+ET +KW G RP +G + T++G+T++ T Sbjct: 182 TLDTPMNRKSMPNADTGTWTPLGFVAETLLKWAGGEGRPASGSLVQLLTESGKTQLLT 239
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Nematostella
Match: EDO42784 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0R5]) HSP 1 Score: 59.6918 bits (143), Expect = 3.367e-10 Identity = 26/67 (38.81%), Postives = 39/67 (58.21%), Query Frame = -1 Query: 1108 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGET 1308 +P +S ILP+TLDT NR MP D WTP+ +V++ W G++RP +G TK+G++ Sbjct: 168 LPPDSTALAILPNTLDTPMNRKFMPEADQSQWTPLEYVAKLMFDWSGGSDRPASGSLCKLITKDGQS 234
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Medaka
Match: qdpra (quinoid dihydropteridine reductase [Source:NCBI gene;Acc:101166857]) HSP 1 Score: 74.3294 bits (181), Expect = 8.448e-15 Identity = 32/68 (47.06%), Postives = 42/68 (61.76%), Query Frame = -1 Query: 1105 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETK 1308 MP + ILP TLDT NR MPN DF SWTP+ +++ETF KW G RP +G + T +G+T+ Sbjct: 164 MPPGAAAVAILPVTLDTPMNRKFMPNADFSSWTPLEYIAETFFKWAAGENRPASGSLMQLLTSDGQTQ 231
BLAST of Lysosomal-associated transmembrane protein 4A vs. Planmine SMEST
Match: SMESG000042736.1 (SMESG000042736.1) HSP 1 Score: 567.77 bits (1462), Expect = 0.000e+0 Identity = 313/313 (100.00%), Postives = 313/313 (100.00%), Query Frame = 3 Query: 72 MIVNEKEFRRCRVFHVVPLTFTFGFVKVILHVAVIVMICTLLMKPDLLDKHETHNKVFGCLCKNKFPKSNNVIDAKTEKHTTNNDVTILLDFKPQMDEIHKLKHSVQTIHQKKLLNENKITQLYWALLMTIFYLMFSLMLLQGILTKNASNMLPXXXXXXXXXXXXXXXXXGHLIVSSDINKLELEFNCLPIGKYFHNINPAISCFIILMLCVTGLMVQFFFIGVIWSCYRYIIASRCQILPTSRNNVNQNGIWGLDLWQVILSPKNRQRRKMPEISDIVVEELPKYEEVLXXXXXXXXXXXXVEKVDQEEKK 1010 MIVNEKEFRRCRVFHVVPLTFTFGFVKVILHVAVIVMICTLLMKPDLLDKHETHNKVFGCLCKNKFPKSNNVIDAKTEKHTTNNDVTILLDFKPQMDEIHKLKHSVQTIHQKKLLNENKITQLYWALLMTIFYLMFSLMLLQGILTKNASNMLPFFCLQLFDFVLDLLWLFGHLIVSSDINKLELEFNCLPIGKYFHNINPAISCFIILMLCVTGLMVQFFFIGVIWSCYRYIIASRCQILPTSRNNVNQNGIWGLDLWQVILSPKNRQRRKMPEISDIVVEELPKYEEVLNTPINTYNPPPYVEKVDQEEKK Sbjct: 1 MIVNEKEFRRCRVFHVVPLTFTFGFVKVILHVAVIVMICTLLMKPDLLDKHETHNKVFGCLCKNKFPKSNNVIDAKTEKHTTNNDVTILLDFKPQMDEIHKLKHSVQTIHQKKLLNENKITQLYWALLMTIFYLMFSLMLLQGILTKNASNMLPFFCLQLFDFVLDLLWLFGHLIVSSDINKLELEFNCLPIGKYFHNINPAISCFIILMLCVTGLMVQFFFIGVIWSCYRYIIASRCQILPTSRNNVNQNGIWGLDLWQVILSPKNRQRRKMPEISDIVVEELPKYEEVLNTPINTYNPPPYVEKVDQEEKK 313
BLAST of Lysosomal-associated transmembrane protein 4A vs. Planmine SMEST
Match: SMESG000010536.1 (SMESG000010536.1) HSP 1 Score: 166.777 bits (421), Expect = 4.816e-50 Identity = 82/100 (82.00%), Postives = 84/100 (84.00%), Query Frame = 3 Query: 633 NCLPIGKYFHNINPAISCFIILMLCVTGLMVQFFFIGVIWSCYRYIIASRCQILPTSRNNVNQNGIWGLDLWQVILSPKNRQRRKMPEISDIVVEELPKY 932 NCLPIGKYFHNINPAISCFIILMLCVTGLMVQFFFIGVIWSCYRYIIASRC ILPTSRNNVNQ+ IWGL+ RKMPEISDIVVEEL KY Sbjct: 42 NCLPIGKYFHNINPAISCFIILMLCVTGLMVQFFFIGVIWSCYRYIIASRCHILPTSRNNVNQSRIWGLE-------------RKMPEISDIVVEELSKY 128
BLAST of Lysosomal-associated transmembrane protein 4A vs. Planmine SMEST
Match: SMESG000032757.1 (SMESG000032757.1) HSP 1 Score: 162.54 bits (410), Expect = 7.780e-49 Identity = 76/84 (90.48%), Postives = 78/84 (92.86%), Query Frame = 3 Query: 684 CFIILMLCVTGLMVQFFFIGVIWSCYRYIIASRCQILPTSRNNVNQNGIWGLDLWQVILSPKNRQRRKMPEISDIVVEELPKYE 935 CFIILMLCVTGLMVQ FFIGVIWSCYRYI ASRC ILPT RNNV QNGIWGLDLWQVILSP+NRQRRKMPEI+DIVVEELPKY Sbjct: 23 CFIILMLCVTGLMVQSFFIGVIWSCYRYIFASRCHILPTPRNNVYQNGIWGLDLWQVILSPQNRQRRKMPEINDIVVEELPKYR 106
BLAST of Lysosomal-associated transmembrane protein 4A vs. Planmine SMEST
Match: SMESG000042735.1 (SMESG000042735.1) HSP 1 Score: 150.984 bits (380), Expect = 7.135e-43 Identity = 70/72 (97.22%), Postives = 72/72 (100.00%), Query Frame = -1 Query: 1093 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPVSFVSETFIKWIEGTERPKNGDFIYFNTKNGETKINTE 1308 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTP+SFV+ETFIKWIEGTERPKNGDFIYFNTKNGETKINTE Sbjct: 161 MPLNSITATILPDTLDTQPNRSSMPNGDFQSWTPLSFVAETFIKWIEGTERPKNGDFIYFNTKNGETKINTE 232
BLAST of Lysosomal-associated transmembrane protein 4A vs. Planmine SMEST
Match: SMESG000011514.1 (SMESG000011514.1) HSP 1 Score: 144.436 bits (363), Expect = 2.009e-42 Identity = 67/72 (93.06%), Postives = 69/72 (95.83%), Query Frame = 3 Query: 633 NCLPIGKYFHNINPAISCFIILMLCVTGLMVQFFFIGVIWSCYRYIIASRCQILPTSRNNVNQNGIWGLDLW 848 NCLPIGKYF+NINPAISCFIILMLCVTGLMVQFFFIGVIWSCY+YIIASR ILPT RNNVNQNGIWGLDLW Sbjct: 6 NCLPIGKYFYNINPAISCFIILMLCVTGLMVQFFFIGVIWSCYQYIIASRYHILPTPRNNVNQNGIWGLDLW 77 The following BLAST results are available for this feature:
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 2
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 3
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 1
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Lysosomal-associated transmembrane protein 4A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Lysosomal-associated transmembrane protein 4A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 3
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Lysosomal-associated transmembrane protein 4A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of Lysosomal-associated transmembrane protein 4A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30010777 ID=SMED30010777|Name=Lysosomal-associated transmembrane protein 4A|organism=Schmidtea mediterranea sexual|type=transcript|length=1308bpback to top protein sequence of SMED30010777-orf-1 >SMED30010777-orf-1 ID=SMED30010777-orf-1|Name=SMED30010777-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=314bp MIVNEKEFRRCRVFHVVPLTFTFGFVKVILHVAVIVMICTLLMKPDLLDKback to top Annotated Terms
The following terms have been associated with this transcript:
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