C2 domain-containing protein 3
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30010766 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of C2 domain-containing protein 3 vs. Ensembl Human
Match: C2CD3 (C2 domain containing 3 centriole elongation regulator [Source:HGNC Symbol;Acc:HGNC:24564]) HSP 1 Score: 280.411 bits (716), Expect = 4.974e-75 Identity = 286/1071 (26.70%), Postives = 466/1071 (43.51%), Query Frame = 1
Query: 2311 KSTVNGYKSDTKSCNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDL--MMSKENTFNGHWNR--NYLTNAFSS---------NELVEHSIEMDIESLGNFLVENYSELPLK---ESYFYIQYYFPLQNSISD--------NNGKNWESAVFRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFESLG---KKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLIN-QHSVDVDSLAETVTQQQLPVRLVNEDHGD-STYPVAVLNIRLCYRTS--VVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGL-GGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDV-RLLGSALFDLSNLILPSDQLNKSVSHILPLWKRGLNNCGNSNITVSMSICGASSPL----------AGYNSDNEEESNLN-------------------ATKIPNNHS------IQNGNGNFHRLRADHQSFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNY---FVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTPTIPLV 5310
K ++G CN+YL +L T E +S I WG + Q V F F + + L+S+ LE+LKNN ++E W+ + L GLVK+P++ F+MSFK+ KI + +L+ YP+++VD ++ + D SG G + V LAMGS QI L + ++E T R ++L ++ N L+EH E+ IE +V+ + L E+ Y+QYYFP+Q+S S NG + FR+A + + + H LP + ++ +L F + G + FE++ + Y P + +AKG LPL+ + ++ QH DV + LP+ E+ + +L++ L YR S + + +T++ I +++I A GLQ AA++L P LQ+ + GVN V L+ + R T + +F P+F E + + + LAE L ++ VYH S SDI + + L+G ++ +LL++ SG G W PI P D GL GL+L +K VG +E+ + F + DR+ +L+ A G W+ +D V MD + TV I L + + K++ L RY+ + +P E +I + ++ L Y RE +LEIQ W YG ND E P+ +GSA DL+ L S + +VS + PL+ R +N + + V + + SS L +S++E+ N +T++P + + Q G + +F V ++VE+A++L S+ G+ L+ + ++ VSF A+E V + +++ +WNF+ +RL LL + + TL FKV++ DE+ +IG +DL LL GF+ V GWYNI D G+CQGQIKV V+P L+
Sbjct: 815 KDFISGESEKQSPCNVYLNCKLFST-EEVTRSVIAWGTT-----QPV-----FNFSQVIPVSLSSKYLERLKNNVMVIETWNKVRSPGQDKLLGLVKLPLHQFYMSFKDAKISRLLLDAQYPVVAVDSYMPVIDVFSGHQNGSLRVFLAMGSSNQIMALQRLKNEEGTLPPFSPRPAHFLDQPTAASVAMAEDRGNGLMEHCFEIHIE-----MVKGLAPLQATVWGEADCYVQYYFPVQHSQSSVLKGPEFLENGITLKP--FRTATTLCVPDPIFNSEHHHSLLLPAEVPVQRLLLSAFSAQGLVPGGGVQFEIWCRYYYPNVRDQKVAKGTLPLSRICAMVTTQHREDVG-----IQTFNLPLTPRIENRKELRNQSSGLLDVGLRYRRSPRTAEGVLAARTVS---------ISVQIIRACGLQAAAKALAEREPALQFSATVGVNASVTTHLSFLPQGEQR--------------RTHPVACSFCPEFSHHVEFTCNLVTQHCSGEACF--LAE--LLEFAEVIFAVYHENTKSA-SDIISIESCKEYLLGVVKVPTKELLIKRSGITG--WYPIILP--EDGGLPHGLEL---------------MQKIVGGLELSISFTHRGDRERVLEAAEHLG----WSFENSLKDFV--RMDEG----EPATVTISTPRLWLPIHCVLLAGHNHIHKNTYCYL-RYKFYDHEAFWTPLKKPKESVNKKQIMVTFKASKRAEVTRGPSLLWYFREERLEIQVWRAYG----------NDSVERPHQTDSWIGSAYVDLARLGERSAR-TLTVSGVYPLFGRNASNLSGAALRVHVVLSSLSSHLEPTHELDSMDCSSHSESEQLPRRNDEVQLSPPEVISCHQKSPASTQVPCSSTTAEVRLTQEGPADL------DGTFAVSILVERAMHL--------SLKGSPLTERKVSIPSCCVSFATADESSPVYTQVVENTDSPIWNFQQQSRLSKELLLDPQQTLVFKVWHKG----------DEERVIGFASVDLSPLLSGFQFVCGWYNITDFSGECQGQIKVAVSPLESLI 1769 HSP 2 Score: 92.0485 bits (227), Expect = 1.336e-17 Identity = 56/175 (32.00%), Postives = 91/175 (52.00%), Query Frame = 1
Query: 46 NTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLEPTQLHKTLEKTY--VKPIITNELNEKAEL 564
+TSLPP + + + +L L +N + W K++ ++V+V WWGE S+G +F PR L + V+T Y +R FT+YL+DM+ L +++I K IGR I+ L QL + I++ K+GE+ + + LEP L +TY P+ T ++ E L
Sbjct: 26 STSLPPLV-EGQLRCFLKLTVNRVIW--KIAKPPTCVLVRVRWWGETSDGTLFCPRDA-LQTEPKAVRTTTRYAIRCGPKQFTSYLTDMAVLVLEVITKLDGLPIGRVQINGLAQLSPTHQINGFFTIVSSTSKKLGELQVSLALEP------LSETYDSYHPLPTTDMTENVLL 190
BLAST of C2 domain-containing protein 3 vs. Ensembl Human
Match: C2CD3 (C2 domain containing 3 centriole elongation regulator [Source:HGNC Symbol;Acc:HGNC:24564]) HSP 1 Score: 280.026 bits (715), Expect = 9.238e-75 Identity = 285/1066 (26.74%), Postives = 464/1066 (43.53%), Query Frame = 1
Query: 2311 KSTVNGYKSDTKSCNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDL--MMSKENTFNGHWNR--NYLTNAFSS---------NELVEHSIEMDIESLGNFLVENYSELPLK---ESYFYIQYYFPLQNSISD--------NNGKNWESAVFRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFESLG---KKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLIN-QHSVDVDSLAETVTQQQLPVRLVNEDHGD-STYPVAVLNIRLCYRTS--VVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLG-GLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDV-RLLGSALFDLSNLILPSDQLNKSVSHILPLWKRGLNNCGNSNITVSMSICGASSPL----------AGYNSDNEEESNLN-------------------ATKIPNNHS------IQNGNGNFHRLRADHQSFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNY---FVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTP 5295
K ++G CN+YL +L T E +S I WG + Q V F F + + L+S+ LE+LKNN ++E W+ + L GLVK+P++ F+MSFK+ KI + +L+ YP+++VD ++ + D SG G + V LAMGS QI L + ++E T R ++L ++ N L+EH E+ IE +V+ + L E+ Y+QYYFP+Q+S S NG + FR+A + + + H LP + ++ +L F + G + FE++ + Y P + +AKG LPL+ + ++ QH DV + LP+ E+ + +L++ L YR S + + +T++ I +++I A GLQ AA++L P LQ+ + GVN V L+ + R T + +F P+F E + + + LAE L ++ VYH S SDI + + L+G ++ +LL++ SG G W PI P D GL GL+L +K VG +E+ + F + DR+ +L+ A G W+ +D V MD + TV I L + + K++ L RY+ + +P E +I + ++ L Y RE +LEIQ W YG ND E P+ +GSA DL+ L S + +VS + PL+ R +N + + V + + SS L +S++E+ N +T++P + + Q G + +F V ++VE+A++L S+ G+ L+ + ++ VSF A+E V + +++ +WNF+ +RL LL + + TL FKV++ DE+ +IG +DL LL GF+ V GWYNI D G+CQGQIKV V+P
Sbjct: 815 KDFISGESEKQSPCNVYLNCKLFST-EEVTRSVIAWGTT-----QPV-----FNFSQVIPVSLSSKYLERLKNNVMVIETWNKVRSPGQDKLLGLVKLPLHQFYMSFKDAKISRLLLDAQYPVVAVDSYMPVIDVFSGHQNGSLRVFLAMGSSNQIMALQRLKNEEGTLPPFSPRPAHFLDQPTAASVAMAEDRGNGLMEHCFEIHIE-----MVKGLAPLQATVWGEADCYVQYYFPVQHSQSSVLKGPEFLENGITLKP--FRTATTLCVPDPIFNSEHHHSLLLPAEVPVQRLLLSAFSAQGLVPGGGVQFEIWCRYYYPNVRDQKVAKGTLPLSRICAMVTTQHREDVG-----IQTFNLPLTPRIENRKELRNQSSGLLDVGLRYRRSPRTAEGVLAARTVS---------ISVQIIRACGLQAAAKALAEREPALQFSATVGVNASVTTHLSFLPQGEQR--------------RTHPVACSFCPEFSHHVEFTCNLVTQHCSGEACF--LAE--LLEFAEVIFAVYHENTKSA-SDIISIESCKEYLLGVVKVPTKELLIKRSGITG--WYPIILP--EDGGLPHGLEL---------------MQKIVGGLELSISFTHRGDRERVLEAAEHLG----WSFENSLKDFV--RMDEG----EPATVTISTPRLWLPIHCVLLAGHNHIHKNTYCYL-RYKFYDHEAFWTPLKKPKESVNKKQIMVTFKASKRAEVTRGPSLLWYFREERLEIQVWRAYG----------NDSVERPHQTDSWIGSAYVDLARLGERSAR-TLTVSGVYPLFGRNASNLSGAALRVHVVLSSLSSHLEPTHELDSMDCSSHSESEQLPRRNDEVQLSPPEVISCHQKSPASTQVPCSSTTAEVRLTQEGPADL------DGTFAVSILVERAMHL--------SLKGSPLTERKVSIPSCCVSFATADESSPVYTQVVENTDSPIWNFQQQSRLSKELLLDPQQTLVFKVWHKG----------DEERVIGFASVDLSPLLSGFQFVCGWYNITDFSGECQGQIKVAVSP 1764 HSP 2 Score: 92.8189 bits (229), Expect = 8.269e-18 Identity = 55/171 (32.16%), Postives = 90/171 (52.63%), Query Frame = 1
Query: 46 NTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLEPTQLHKTLEKTY--VKPIITNELNE 552
+TSLPP + + + +L L +N + W K++ ++V+V WWGE S+G +F PR L + V+T Y +R FT+YL+DM+ L +++I K IGR I+ L QL + I++ K+GE+ + + LEP L +TY P+ T ++ E
Sbjct: 26 STSLPPLV-EGQLRCFLKLTVNRVIW--KIAKPPTCVLVRVRWWGETSDGTLFCPRDA-LQTEPKAVRTTTRYAIRCGPKQFTSYLTDMAVLVLEVITKLDGLPIGRVQINGLAQLSPTHQINGFFTIVSSTSKKLGELQVSLALEP------LSETYDSYHPLPTTDMTE 186
BLAST of C2 domain-containing protein 3 vs. Ensembl Human
Match: C2CD3 (C2 domain containing 3 centriole elongation regulator [Source:HGNC Symbol;Acc:HGNC:24564]) HSP 1 Score: 160.229 bits (404), Expect = 3.653e-39 Identity = 171/655 (26.11%), Postives = 273/655 (41.68%), Query Frame = 1
Query: 3466 IRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGL-GGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDV-RLLGSALFDLSNLILPSDQLNKSVSHILPLWKRGLNNCGNSNITVSMSICGASSPL----------AGYNSDNEEESNLN-------------------ATKIPNNHSI------QNGNGNFHRLRADHQSFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNY---FVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTPTIPLV 5310
I +++I A GLQ AA++L P LQ+ + GVN V L+ + R T + +F P+F E + + + LAE L ++ VYH S SDI + + L+G ++ +LL++ SG G W PI P D GL GL+L +K VG +E+ + F + DR+ +L+ A G W+ +D V MD + TV I L + + K++ L RY+ + +P E +I + ++ L Y RE +LEIQ W YG ND E P+ +GSA DL+ L S + +VS + PL+ R +N + + V + + SS L +S++E+ N +T++P + + Q G + +F V ++VE+A++L S+ G+ L+ + ++ VSF A+E V + +++ +WNF+ +RL LL + + TL FKV++ DE+ +IG +DL LL GF+ V GWYNI D G+CQGQIKV V+P L+
Sbjct: 7 ISVQIIRACGLQAAAKALAEREPALQFSATVGVNASVTTHLSFLPQGEQR--------------RTHPVACSFCPEFSHHVEFTCNLVTQHCSGEACF--LAE--LLEFAEVIFAVYHENTKSA-SDIISIESCKEYLLGVVKVPTKELLIKRSGITG--WYPIILP--EDGGLPHGLEL---------------MQKIVGGLELSISFTHRGDRERVLEAAEHLG----WSFENSLKDFV--RMDEG----EPATVTISTPRLWLPIHCVLLAGHNHIHKNTYCYL-RYKFYDHEAFWTPLKKPKESVNKKQIMVTFKASKRAEVTRGPSLLWYFREERLEIQVWRAYG----------NDSVERPHQTDSWIGSAYVDLARLGERSAR-TLTVSGVYPLFGRNASNLSGAALRVHVVLSSLSSHLEPTHELDSMDCSSHSESEQLPRRNDEVQLSPPEVISCHQKSPASTQVPCSSTTAEVRLTQEGPADLD------GTFAVSILVERAMHL--------SLKGSPLTERKVSIPSCCVSFATADESSPVYTQVVENTDSPIWNFQQQSRLSKELLLDPQQTLVFKVWHKG----------DEERVIGFASVDLSPLLSGFQFVCGWYNITDFSGECQGQIKVAVSPLESLI 577
BLAST of C2 domain-containing protein 3 vs. Ensembl Human
Match: C2CD3 (C2 domain containing 3 centriole elongation regulator [Source:HGNC Symbol;Acc:HGNC:24564]) HSP 1 Score: 139.428 bits (350), Expect = 9.629e-33 Identity = 153/592 (25.84%), Postives = 247/592 (41.72%), Query Frame = 1
Query: 3655 KSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGL-GGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDV-RLLGSALFDLSNLILPSDQLNKSVSHILPLWKRGLNNCGNSNITVSMSICGASSPL----------AGYNSDNEEESNLN-------------------ATKIPNNHSI------QNGNGNFHRLRADHQSFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNY---FVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTPTIPLV 5310
+ T + +F P+F E + + + LAE L ++ VYH S SDI + + L+G ++ +LL++ SG G W PI P D GL GL+L +K VG +E+ + F + DR+ +L+ A G W+ +D V MD + TV I L + + K++ L RY+ + +P E +I + ++ L Y RE +LEIQ W YG ND E P+ +GSA DL+ L S + +VS + PL+ R +N + + V + + SS L +S++E+ N +T++P + + Q G + +F V ++VE+A++L S+ G+ L+ + ++ VSF A+E V + +++ +WNF+ +RL LL + + TL FKV++ DE+ +IG +DL LL GF+ V GWYNI D G+CQGQIKV V+P L+
Sbjct: 4 RRTHPVACSFCPEFSHHVEFTCNLVTQHCSGEACF--LAE--LLEFAEVIFAVYHENTKSA-SDIISIESCKEYLLGVVKVPTKELLIKRSGITG--WYPIILP--EDGGLPHGLEL---------------MQKIVGGLELSISFTHRGDRERVLEAAEHLG----WSFENSLKDFV--RMDEG----EPATVTISTPRLWLPIHCVLLAGHNHIHKNTYCYL-RYKFYDHEAFWTPLKKPKESVNKKQIMVTFKASKRAEVTRGPSLLWYFREERLEIQVWRAYG----------NDSVERPHQTDSWIGSAYVDLARLGERSAR-TLTVSGVYPLFGRNASNLSGAALRVHVVLSSLSSHLEPTHELDSMDCSSHSESEQLPRRNDEVQLSPPEVISCHQKSPASTQVPCSSTTAEVRLTQEGPADLD------GTFAVSILVERAMHL--------SLKGSPLTERKVSIPSCCVSFATADESSPVYTQVVENTDSPIWNFQQQSRLSKELLLDPQQTLVFKVWHKG----------DEERVIGFASVDLSPLLSGFQFVCGWYNITDFSGECQGQIKVAVSPLESLI 525
BLAST of C2 domain-containing protein 3 vs. Ensembl Human
Match: C2CD3 (C2 domain containing 3 centriole elongation regulator [Source:HGNC Symbol;Acc:HGNC:24564]) HSP 1 Score: 92.4337 bits (228), Expect = 2.598e-18 Identity = 56/175 (32.00%), Postives = 91/175 (52.00%), Query Frame = 1
Query: 46 NTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLEPTQLHKTLEKTY--VKPIITNELNEKAEL 564
+TSLPP + + + +L L +N + W K++ ++V+V WWGE S+G +F PR L + V+T Y +R FT+YL+DM+ L +++I K IGR I+ L QL + I++ K+GE+ + + LEP L +TY P+ T ++ E L
Sbjct: 26 STSLPPLV-EGQLRCFLKLTVNRVIW--KIAKPPTCVLVRVRWWGETSDGTLFCPRDA-LQTEPKAVRTTTRYAIRCGPKQFTSYLTDMAVLVLEVITKLDGLPIGRVQINGLAQLSPTHQINGFFTIVSSTSKKLGELQVSLALEP------LSETYDSYHPLPTTDMTENVLL 190
BLAST of C2 domain-containing protein 3 vs. Ensembl Zebrafish
Match: c2cd3 (C2 domain containing 3 centriole elongation regulator [Source:ZFIN;Acc:ZDB-GENE-060503-104]) HSP 1 Score: 238.039 bits (606), Expect = 2.384e-62 Identity = 266/1027 (25.90%), Postives = 466/1027 (45.37%), Query Frame = 1
Query: 2353 NLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDLMMSKENTFN--------GHW--NRNYLTNAFSSNELVEHSIEMDIESLGNFLVENYSELPLK-----ESYFYIQYYFPLQN-SISDNNGKNWESAV----FRSANCQVERNVDISDTNRHRFRLPIDSSL-KAILN--KHFESLGKKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLINQHSVDVDSLAETVTQQ-QLPVRLVNEDHGDST-YPVAVLNIRLCYRTSVVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSS----PNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDVRLLGSALFDLSNLILPSDQLNKSVSHILPLWKR-GLNNCGNS---NITVSM-SICGASSPLAGYNSDNEEESNLN-ATKIPNNHS------IQN--GNGNFHRLRADHQSFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNY---FVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTP 5295
N+YL +LL + E +S + WG + F F + + L+ LLE++KNN ++EVW ++ L GLVK+P++ F+MSF++ KI + +L + YP++ VD ++ + D SG ++G + V LAMG QQ+ L +++ + H +R + +S+ L+EH + +E + +PL+ E+ YIQY FP QN S D + ES V FRS + H P D + K +LN H G + FE++ + Y P + +A+G LP++ L ++ + +T Q LP+ + D+ P +L + + Y++ +++ + + P + + +++ A GLQ AA++L + L Y S G+N + L+ + +SR ST+ R+F P+F+ +E ++ ++ + +LAE + Q V ++ VF+ + + S I++G +I +ADL+ + SG G W + P ++ + L S G +E+ + F +DR+ +L A G+ + + E ++ H + + ++ + L ++ + P + S RY++++Q SS P N + G + + R + L YLRE KLE+Q W +G E R + HN + RL+GSA DLS L Q ++++S + PL+KR +N CG + +ITV+ S+ + +S EE+ N + AT P+ IQ+ + + +F ++ V++A++L S+ G L+ + VS+ A++ VT+++IK + VW+ + + RL LL + + L FKV++ GE+ E+V IG V +DL LL GF+ V GWYNI D G CQGQ+KV V+P
Sbjct: 148 NVYLNCKLLGS-DETARSAVSWGQKHPT----------FSFTQVAPVALSPRLLERMKNNMMVIEVWLRASSSDHDKLLGLVKLPLHQFYMSFRDPKISELLLQSQYPVVGVDSYMPVVDVFSGSTRGNLRVCLAMGQAQQVMALQRMRDDELSHDTPVPRPAHMLDHRPHTEAKATSDVLLEHVFMVRVERVKGL-------MPLQSTVWGEADCYIQYSFPAQNESREDMDTHAVESHVDLKAFRSETTLCVPDPVFGHNETHVLLAPPDVPVQKLLLNSLAHQGLRGGGGVQFEVWCRYYYPNVRDQLVARGLLPMSKLCAMVT-----MQKQGQTEAQHFSLPLIPRTDRPVDAQPQPPGLLEVTVQYKSRPMRSVGLKSGV---VPSRRVTLVVQIHRAAGLQAAAKALADSDSSLDYYSKVGLNSFITVQLSFLPDSESR--------------STRVAARSFCPEFEHHTEFCCNLLVQRDSGESV--SLAE-----LLQDAVAIF-TVFNRDTRKMVDT-RSKDIVLGTVKIKLADLIHKRSGISG--WYSLSHPQSTSSSSSSHGLT-----------------SAGGLEISISFSHHADRERVLSSACGLGWDIEEHSEDEASTEDEDALEAHSKSLTF-SISMPRAWLP---IHCLLLPGHEDLQRSTYCYYRYKLYEQHTFSSELRHPVADKNHGD-EGLATVAFQGSRSVILRRTRPLHWYLREEKLEVQLWVTFGKEKR-----VRPHNAD----RLVGSAFVDLSALAGSLKQ-HQTISGVYPLFKRSAVNLCGAALRVHITVTTDSLTLEPQVIEQLHSSGEEDLNEDLATTSPSRPQSPSKPLIQSEVTTEDPPSTQPIENTFIANITVDRAMHL--------SLKGCPLAERGGGLPSCCVSYATADDTGTVTTALIKDNECPVWDHQQECRLSKELLLDPQQCLVFKVWHK-------GEV--ERV-IGFVSVDLSPLLSGFQSVCGWYNITDFSGQCQGQLKVSVSP 1073
BLAST of C2 domain-containing protein 3 vs. Ensembl Zebrafish
Match: c2cd3 (C2 domain containing 3 centriole elongation regulator [Source:ZFIN;Acc:ZDB-GENE-060503-104]) HSP 1 Score: 238.039 bits (606), Expect = 2.384e-62 Identity = 266/1027 (25.90%), Postives = 466/1027 (45.37%), Query Frame = 1
Query: 2353 NLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDLMMSKENTFN--------GHW--NRNYLTNAFSSNELVEHSIEMDIESLGNFLVENYSELPLK-----ESYFYIQYYFPLQN-SISDNNGKNWESAV----FRSANCQVERNVDISDTNRHRFRLPIDSSL-KAILN--KHFESLGKKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLINQHSVDVDSLAETVTQQ-QLPVRLVNEDHGDST-YPVAVLNIRLCYRTSVVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSS----PNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDVRLLGSALFDLSNLILPSDQLNKSVSHILPLWKR-GLNNCGNS---NITVSM-SICGASSPLAGYNSDNEEESNLN-ATKIPNNHS------IQN--GNGNFHRLRADHQSFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNY---FVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTP 5295
N+YL +LL + E +S + WG + F F + + L+ LLE++KNN ++EVW ++ L GLVK+P++ F+MSF++ KI + +L + YP++ VD ++ + D SG ++G + V LAMG QQ+ L +++ + H +R + +S+ L+EH + +E + +PL+ E+ YIQY FP QN S D + ES V FRS + H P D + K +LN H G + FE++ + Y P + +A+G LP++ L ++ + +T Q LP+ + D+ P +L + + Y++ +++ + + P + + +++ A GLQ AA++L + L Y S G+N + L+ + +SR ST+ R+F P+F+ +E ++ ++ + +LAE + Q V ++ VF+ + + S I++G +I +ADL+ + SG G W + P ++ + L S G +E+ + F +DR+ +L A G+ + + E ++ H + + ++ + L ++ + P + S RY++++Q SS P N + G + + R + L YLRE KLE+Q W +G E R + HN + RL+GSA DLS L Q ++++S + PL+KR +N CG + +ITV+ S+ + +S EE+ N + AT P+ IQ+ + + +F ++ V++A++L S+ G L+ + VS+ A++ VT+++IK + VW+ + + RL LL + + L FKV++ GE+ E+V IG V +DL LL GF+ V GWYNI D G CQGQ+KV V+P
Sbjct: 148 NVYLNCKLLGS-DETARSAVSWGQKHPT----------FSFTQVAPVALSPRLLERMKNNMMVIEVWLRASSSDHDKLLGLVKLPLHQFYMSFRDPKISELLLQSQYPVVGVDSYMPVVDVFSGSTRGNLRVCLAMGQAQQVMALQRMRDDELSHDTPVPRPAHMLDHRPHTEAKATSDVLLEHVFMVRVERVKGL-------MPLQSTVWGEADCYIQYSFPAQNESREDMDTHAVESHVDLKAFRSETTLCVPDPVFGHNETHVLLAPPDVPVQKLLLNSLAHQGLRGGGGVQFEVWCRYYYPNVRDQLVARGLLPMSKLCAMVT-----MQKQGQTEAQHFSLPLIPRTDRPVDAQPQPPGLLEVTVQYKSRPMRSVGLKSGV---VPSRRVTLVVQIHRAAGLQAAAKALADSDSSLDYYSKVGLNSFITVQLSFLPDSESR--------------STRVAARSFCPEFEHHTEFCCNLLVQRDSGESV--SLAE-----LLQDAVAIF-TVFNRDTRKMVDT-RSKDIVLGTVKIKLADLIHKRSGISG--WYSLSHPQSTSSSSSSHGLT-----------------SAGGLEISISFSHHADRERVLSSACGLGWDIEEHSEDEASTEDEDALEAHSKSLTF-SISMPRAWLP---IHCLLLPGHEDLQRSTYCYYRYKLYEQHTFSSELRHPVADKNHGD-EGLATVAFQGSRSVILRRTRPLHWYLREEKLEVQLWVTFGKEKR-----VRPHNAD----RLVGSAFVDLSALAGSLKQ-HQTISGVYPLFKRSAVNLCGAALRVHITVTTDSLTLEPQVIEQLHSSGEEDLNEDLATTSPSRPQSPSKPLIQSEVTTEDPPSTQPIENTFIANITVDRAMHL--------SLKGCPLAERGGGLPSCCVSYATADDTGTVTTALIKDNECPVWDHQQECRLSKELLLDPQQCLVFKVWHK-------GEV--ERV-IGFVSVDLSPLLSGFQSVCGWYNITDFSGQCQGQLKVSVSP 1073
BLAST of C2 domain-containing protein 3 vs. Ensembl Zebrafish
Match: c2cd3 (C2 domain containing 3 centriole elongation regulator [Source:ZFIN;Acc:ZDB-GENE-060503-104]) HSP 1 Score: 235.343 bits (599), Expect = 2.338e-61 Identity = 313/1254 (24.96%), Postives = 544/1254 (43.38%), Query Frame = 1
Query: 1768 SLSLDHVSEFPVTFTNSAIIQKWWRGIVRFKLICQDSNKKETV-VGVGVVPLRNIISTNNFYRLIPIRLPRNKSAKSNTRMVIGSXXXXXXXXXXXXKGFNSSDKKPEILFQDSSDSRNQISYYHPKXXXXXXXXXXXXXXXXERANFPSQQVSHISR------SSIKIPPTSLQS----LLYVSSIRYVNPKST----------VNGYKSDTKSC--NLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDLMMSKENTFN--------GHW--NRNYLTNAFS---------SNELVEHSIEMDIESLGNFLVENYSELPLK-----ESYFYIQYYFPLQN-SISDNNGKNWESAV----FRSANCQVERNVDISDTNRHRFRLPIDSSL-KAILN--KHFESLGKKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLINQHSVDVDSLAETVTQQ-QLPVRLVNEDHGDST-YPVAVLNIRLCYRTSVVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSS----PNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDVRLLGSALFDLSNLILPSDQLNKSVSHILPLWKR-GLNNCGNS---NITVSM-SICGASSPLAGYNSDNEEESNLN-ATKIPNNHS------IQN--GNGNFHRLRADHQSFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNY---FVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTP 5295
++S H S FPV F+ S+I Q W V FK+ + S +K + +G + PL +++ + + I LP + + + +G L ++ F+ + D N S P + S+ E VS+ R SI IPP +S + + SSI+ + T NG + N+YL +LL + E +S + WG + F F + + L+ LLE++KNN ++EVW ++ L GLVK+P++ F+MSF++ KI + +L + YP++ VD ++ + D SG ++G + V LAMG QQ+ L +++ + H +R + S S+ L+EH + +E + + PL+ E+ YIQY FP QN S D + ES V FRS + H P D + K +LN H G + FE++ + Y P + +A+G LP++ L ++ + +T Q LP+ + D+ P +L + + Y++ +++ + + P + + +++ A GLQ AA++L + L Y S G+N + L+ + +SR ST+ R+F P+F+ +E ++ ++ + +LAE + Q V ++ VF+ + + S I++G +I +ADL+ + SG G W + P ++ S + S G +E+ + F +DR+ +L A G+ + + E ++ H + + ++ + L ++ + P + S RY++++Q SS P N + G + + R + L YLRE KLE+Q W +G E R + HN + RL+GSA DLS L Q ++++S + PL+KR +N CG + +ITV+ S+ + +S EE+ N + AT P+ IQ+ + + +F ++ V++A++L S+ G L+ + VS+ A++ VT+++IK + VW+ + + RL LL + + L FKV++ GE+ E+V IG V +DL LL GF+ V GWYNI D G CQGQ+KV V+P
Sbjct: 463 AVSFQHQSLFPVKFSRSSIKQ-WCEMKVTFKIYSKYSLQKTPILIGSAMFPLSSLMQSESLS--ISSALPVQTANGNTDKQQVGPL---------------------KVTFELAEDKNNFSSKKRPAKQMLSPQRPLPSLLTEEHDEPKGLCVSNSRRDPSPQAQSILIPPARSRSTSPHVRFQSSIQQQEMEDTEILLHMLLMVPNGKDLNCAPMQPNVYLNCKLLGS-DETARSAVSWGQKHPT----------FSFTQVAPVALSPRLLERMKNNMMVIEVWLRASSSDHDKLLGLVKLPLHQFYMSFRDPKISELLLQSQYPVVGVDSYMPVVDVFSGSTRGNLRVCLAMGQAQQVMALQRMRDDELSHDTPVPRPAHMLDHRPHTEAKASLRCDRMHATSDVLLEHVFMVRVERVKGLM-------PLQSTVWGEADCYIQYSFPAQNESREDMDTHAVESHVDLKAFRSETTLCVPDPVFGHNETHVLLAPPDVPVQKLLLNSLAHQGLRGGGGVQFEVWCRYYYPNVRDQLVARGLLPMSKLCAMVT-----MQKQGQTEAQHFSLPLIPRTDRPVDAQPQPPGLLEVTVQYKSRPMRSVGLKSGV---VPSRRVTLVVQIHRAAGLQAAAKALADSDSSLDYYSKVGLNSFITVQLSFLPDSESR--------------STRVAARSFCPEFEHHTEFCCNLLVQRDSGESV--SLAE-----LLQDAVAIF-TVFNRDTRKMVDTR-SKDIVLGTVKIKLADLIHKRSGISG--WYSLSHP-----------------QSTSSSSSSHGLTSAGGLEISISFSHHADRERVLSSACGLGWDIEEHSEDEASTEDEDALEAHSKSLTF-SISMPRAWLP---IHCLLLPGHEDLQRSTYCYYRYKLYEQHTFSSELRHPVADKNHGD-EGLATVAFQGSRSVILRRTRPLHWYLREEKLEVQLWVTFGKEKR-----VRPHNAD----RLVGSAFVDLSALAGSLKQ-HQTISGVYPLFKRSAVNLCGAALRVHITVTTDSLTLEPQVIEQLHSSGEEDLNEDLATTSPSRPQSPSKPLIQSEVTTEDPPSTQPIENTFIANITVDRAMHL--------SLKGCPLAERGGGLPSCCVSYATADDTGTVTTALIKDNECPVWDHQQECRLSKELLLDPQQCLVFKVWHK-------GEV--ERV-IGFVSVDLSPLLSGFQSVCGWYNITDFSGQCQGQLKVSVSP 1591 HSP 2 Score: 68.5514 bits (166), Expect = 1.225e-10 Identity = 48/183 (26.23%), Postives = 88/183 (48.09%), Query Frame = 1
Query: 34 NVVVNTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLEPTQLHKTLEKTYVKPIITNELNEKAELRTSLNK 582
+V +TS+PP + F L + K + + ++++ WWGE SNG F PR + ++ +K+ A +PVR T+YL+DM L +D++ K H I +A I + +L + ++ +++ K+GE+ + + LE L + E + P L+ + + T NK
Sbjct: 21 DVSPSTSIPPLVEGQLRCF---LRVTVSKALWTIIRPPPVTLIRLRWWGESSNGTFFRPR--DGHAEQKGLKSTARFPVRCGPKQLTSYLTDMGSLVLDVLTKVDHLPIAQAQIPGIARLSFSHSINGYFTLVSPTSEKLGELQVTLALE--ALTEGYESSSSVPTTDMSLDAQTLVVTDHNK 196
BLAST of C2 domain-containing protein 3 vs. Ensembl Xenopus
Match: c2cd3 (C2 calcium-dependent domain containing 3 [Source:NCBI gene;Acc:780184]) HSP 1 Score: 272.707 bits (696), Expect = 1.457e-72 Identity = 272/1043 (26.08%), Postives = 466/1043 (44.68%), Query Frame = 1
Query: 2350 CNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDL--MMSKENTFNGHWNR--NYLTNAFSSNE-------LVEHSIEMDIESLGNFLVENYSELPLK-----ESYFYIQYYFPLQNSISDNNGKNWESAV----FRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFESL---GKKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLIN-QHSVDVDSLAETVTQQQLPVRLVNEDHGD-STYPVAVLNIRLCYRTSVVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSG---YVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSP--NFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDV-RLLGSALFDLSNLILPSDQLNK--SVSHILPLWKRGLNNCGNSNITVSMSICGASSP--------LAGYNSDNEEE----SNLNATKIPNNHSIQN----GNGNFHRLRADHQ---------SFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPL---NYFVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTP 5295
CN YL +L ++A E +S ++WG+++ + F + L L + LLE++KNN I+E+W+ + L GL K+P++ F+MSF + KI + +L YP+++VD ++ I D SG +G++ VLLA+GS Q+ L + ++E T R ++L SS++ + +H E+ +E++ PL+ E+ ++QYYFP S E A+ R+A + +D H D+ ++ +L + G + FE++ + Y P + +AKG LPL+ L ++ QH DV A + LP+ +E + P +LN+ + YR S ++N V +S I +++ A+GLQ AA + QY + GVN +V ++ + + ++T+T+ RTF P+FD E +I N +LAE + ++ + ++H S+ S T P +G RI L+ + SG G W P+ P +S KL ++ L+++ VG +E+ + F SDR +L++A G Y + + TE W ++ ++V+I +I L L + KS+ L RY+ + + SP ++ED I ++ ++ L YLRE ++EIQ W YG + + P D RL+G A DL L S+ ++ +VS + PL+KR +++ + + V +++ A P AG S +E E ++ ++ + + S +N L A Q +F ++VE+A++L S+ GT L+ + VS+P A + VT+ +I +WNF+ RL LL + + L FKV++ D + ++G +DL LL GF+ + GWYNIVD G CQGQ+KV +TP
Sbjct: 797 CNSYLNCKL-FSAQEATRSSVVWGSTQ----------PQYNFSQVAPLTLNARLLERMKNNVMIIEIWNRVASPGQDQLLGLAKLPLHQFYMSFSDPKITRLLLQAQYPVVAVDSYVPIIDVFSGCDRGKLKVLLAIGSGDQVVALQRLKNEEGTSQTAMPRPAHFLDPPLSSSQMGRPQEGMTDHIFEIHVENVKGL-------TPLQSTVWGEADCFVQYYFPAHGPDSHTAIDLPEIAMTLKPVRTATTLCVPDPVFNDRQSHTIVAQSDTPVQRLLLGAYSMQGLSGGGGVPFEIWCRYYYPNVRDQMVAKGVLPLSRLCAMVTMQHREDVGIQAFS-----LPLIPRSEKSAELPPQPSGLLNVNVTYRRS-MRNPVGMLATRMAS------ISVQIHRASGLQAAARLVAQQDASFQYSADVGVNAYVT--------------IHPAFLPDVELRNTRTVARTFCPEFDHHYEFPCNMVIQRNNGEAC--SLAEVLY--FSEIVLSIHHQNVASVGS--TRPQPVRDYHLGMVRIPCRQLITKRSGVSG--WYPVTVPEDS-------KL----PTDSTILHSV-----VGGLELSVHFAHHSDRDRVLEVARGLGWNEYNEDFQEAIATEADEWHKRED----LVNLSVNIPKIWL--PLHCLLLAGHKHIHKSTYCYL-RYKFYDREAVCSPLRRPRLSEDGQQATIMFELSENRELIKH--QPLVWYLREERMEIQVWRSYGKDT---------NGPRPQDTDRLIGCAYVDLKAL---SENTSRTLAVSGVYPLFKRNVSSLWGAAVRVHLALSSAYHPSNSSRRLSCAGERSQSEGEEWAPTSGDSFEEKQDDSAKNDKPEAKTEVPLLDAKEQPVGEVDLKNTFAASIVVERAMHL--------SLKGTPLTERAAATPTCCVSYPVAGCSEPVTTPVIANTDSPLWNFQHQARLHKELLLDPQQRLVFKVWHKT----------DVERVVGFASVDLSPLLSGFQSICGWYNIVDFVGQCQGQVKVSITP 1732 HSP 2 Score: 77.411 bits (189), Expect = 3.025e-13 Identity = 49/151 (32.45%), Postives = 78/151 (51.66%), Query Frame = 1
Query: 34 NVVVNTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLEP 486
+V +TSLPP + + + +L + ++ I W V ++V++ WWGE +NG +F PR + K KT Y VR FT+YL+DM L +++ K H IGRA I + QL + I++ K+GE+ + + LEP
Sbjct: 21 DVTPSTSLPPLV-EGQVRSFLQVTVSKILW--TVPKPPPSVLVRLRWWGETANGTVFRPRDSSQTEQK-GAKTTTRYAVRCGPKQFTSYLTDMGMLVFEVMTKLDHFPIGRAQISGIAQLSLAHPVSGFFTIVSPTSEKLGELQVSVQLEP 167
BLAST of C2 domain-containing protein 3 vs. Ensembl Xenopus
Match: c2cd3 (C2 calcium-dependent domain containing 3 [Source:NCBI gene;Acc:780184]) HSP 1 Score: 271.552 bits (693), Expect = 2.437e-72 Identity = 272/1042 (26.10%), Postives = 466/1042 (44.72%), Query Frame = 1
Query: 2350 CNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDL--MMSKENTFNGHWNR--NYLTNAFSSNE------LVEHSIEMDIESLGNFLVENYSELPLK-----ESYFYIQYYFPLQNSISDNNGKNWESAV----FRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFESL---GKKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLIN-QHSVDVDSLAETVTQQQLPVRLVNEDHGD-STYPVAVLNIRLCYRTSVVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSG---YVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSP--NFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDV-RLLGSALFDLSNLILPSDQLNK--SVSHILPLWKRGLNNCGNSNITVSMSICGASSP--------LAGYNSDNEEE----SNLNATKIPNNHSIQN----GNGNFHRLRADHQ---------SFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPL---NYFVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTP 5295
CN YL +L ++A E +S ++WG+++ + F + L L + LLE++KNN I+E+W+ + L GL K+P++ F+MSF + KI + +L YP+++VD ++ I D SG +G++ VLLA+GS Q+ L + ++E T R ++L SS++ + +H E+ +E++ PL+ E+ ++QYYFP S E A+ R+A + +D H D+ ++ +L + G + FE++ + Y P + +AKG LPL+ L ++ QH DV A + LP+ +E + P +LN+ + YR S ++N V +S I +++ A+GLQ AA + QY + GVN +V ++ + + ++T+T+ RTF P+FD E +I N +LAE + ++ + ++H S+ S T P +G RI L+ + SG G W P+ P +S KL ++ L+++ VG +E+ + F SDR +L++A G Y + + TE W ++ ++V+I +I L L + KS+ L RY+ + + SP ++ED I ++ ++ L YLRE ++EIQ W YG + + P D RL+G A DL L S+ ++ +VS + PL+KR +++ + + V +++ A P AG S +E E ++ ++ + + S +N L A Q +F ++VE+A++L S+ GT L+ + VS+P A + VT+ +I +WNF+ RL LL + + L FKV++ D + ++G +DL LL GF+ + GWYNIVD G CQGQ+KV +TP
Sbjct: 583 CNSYLNCKL-FSAQEATRSSVVWGSTQ----------PQYNFSQVAPLTLNARLLERMKNNVMIIEIWNRVASPGQDQLLGLAKLPLHQFYMSFSDPKITRLLLQAQYPVVAVDSYVPIIDVFSGCDRGKLKVLLAIGSGDQVVALQRLKNEEGTSQTAMPRPAHFLDPPLSSSQVSPYEGMTDHIFEIHVENVKGL-------TPLQSTVWGEADCFVQYYFPAHGPDSHTAIDLPEIAMTLKPVRTATTLCVPDPVFNDRQSHTIVAQSDTPVQRLLLGAYSMQGLSGGGGVPFEIWCRYYYPNVRDQMVAKGVLPLSRLCAMVTMQHREDVGIQAFS-----LPLIPRSEKSAELPPQPSGLLNVNVTYRRS-MRNPVGMLATRMAS------ISVQIHRASGLQAAARLVAQQDASFQYSADVGVNAYVT--------------IHPAFLPDVELRNTRTVARTFCPEFDHHYEFPCNMVIQRNNGEAC--SLAEVLY--FSEIVLSIHHQNVASVGS--TRPQPVRDYHLGMVRIPCRQLITKRSGVSG--WYPVTVPEDS-------KL----PTDSTILHSV-----VGGLELSVHFAHHSDRDRVLEVARGLGWNEYNEDFQEAIATEADEWHKRED----LVNLSVNIPKIWL--PLHCLLLAGHKHIHKSTYCYL-RYKFYDREAVCSPLRRPRLSEDGQQATIMFELSENRELIKH--QPLVWYLREERMEIQVWRSYGKDT---------NGPRPQDTDRLIGCAYVDLKAL---SENTSRTLAVSGVYPLFKRNVSSLWGAAVRVHLALSSAYHPSNSSRRLSCAGERSQSEGEEWAPTSGDSFEEKQDDSAKNDKPEAKTEVPLLDAKEQPVGEVDLKNTFAASIVVERAMHL--------SLKGTPLTERAAATPTCCVSYPVAGCSEPVTTPVIANTDSPLWNFQHQARLHKELLLDPQQRLVFKVWHKT----------DVERVVGFASVDLSPLLSGFQSICGWYNIVDFVGQCQGQVKVSITP 1517 HSP 2 Score: 71.633 bits (174), Expect = 1.738e-11 Identity = 48/151 (31.79%), Postives = 77/151 (50.99%), Query Frame = 1
Query: 7 ILYVMNQNINVVVNTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGE 459
I++V+ +V +TSLPP + + + +L + ++ I W V ++V++ WWGE +NG +F PR + K KT Y VR FT+YL+DM L +++ K H IGRA I + QL + I++ K+GE
Sbjct: 11 IIFVLGLT-DVTPSTSLPPLV-EGQVRSFLQVTVSKILW--TVPKPPPSVLVRLRWWGETANGTVFRPRDSSQTEQK-GAKTTTRYAVRCGPKQFTSYLTDMGMLVFEVMTKLDHFPIGRAQISGIAQLSLAHPVSGFFTIVSPTSEKLGE 156
BLAST of C2 domain-containing protein 3 vs. Ensembl Mouse
Match: C2cd3 (C2 calcium-dependent domain containing 3 [Source:MGI Symbol;Acc:MGI:2142166]) HSP 1 Score: 277.715 bits (709), Expect = 1.309e-74 Identity = 334/1321 (25.28%), Postives = 556/1321 (42.09%), Query Frame = 1
Query: 1621 YFIEYKFPTN---------ALYTADKDKENLSNSMSTTRVLVKQTGFKCNISDSNGIKSLSLDHVSEFPVTFTNSAIIQKWWRGIVRFKLICQDS-NKKETVVGVGVVPLRNIISTN--NFYRLIPIRLPRNKSA----KSNTRMVIG-------SXXXXXXXXXXXXKGFNSSDKKPEILFQDSSDSRNQIS--YYHPKXXXXXXXXXXXXXXXXERAN--------FPSQQVSHISRSSIKIPPTSLQSLLYVSSIRYVNPKSTVNGYKSDTKSCNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDLMMSKENTFNGHWNRNYLTNAFSSNELVEHSIEMDIESLGNFLVENYSE---------LPLK-----ESYFYIQYYFPLQNS-ISDNNGKNW-ESAV----FRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFESLG---KKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLIN---QHSVDVDSLAETVTQQ-QLPVRLVNEDHGDSTYPVAVLNIRLCYRTS--VVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDV-RLLGSALFDLSNLILPSDQLNKSVSHILPLWKRGLNNCGNSNITVSMSICGASSPLAGYNSDNEEESNL---------------NATKIPNNHSIQ--------NGNGNFHRLRADHQ-------SFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNY---FVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTP 5295
+F+EY FP AL T + L++S T V+ Q F C PV F +I+ WW + F++ + + KK V+G +PLR +I + +F +P++ S+ K +V+G S L ++ A SSD QD++ +RN S H + T + + PS + H S K L LL V + K V G + SCN+YL +L T E +S + WG ++ F F + + LTS+ LE+LKNN I+E W+ + L GLVK+P++ F+MSFK+ KI + +L+ YP+++VD ++ + D SG G + V LAMGS QI +M+ + G A ++ S+ M E G L+E++ E +PL+ E+ Y+QYYFP Q+S S G ++ E+ + FR++ + + + H LP D ++ +L F S G + FE++ + Y P + +AKG LPL+ + ++ + V + S +T + + L N+ G L++ L YR S + + + ++ I + +I A GLQ AA++L P LQ+ + GVN V L+ + K + + T+ + +F P+F E + + + LAE L ++ +YH S+ SDIT + L+G ++ DLL++ SG G W P+ P D GL + L ++ K VG +E+ + F DR+ +L+ A G W+ +DLV + + TV I L + + + K++ L RY+++ Q +P E ++ I ++ S L Y RE KLEIQ W YG ND+ E P+ +GSA DLS L S + ++S + PL+ R ++ + + + + + SPL+ + E ++ +A ++ H +Q +GN ++ + +F V ++VE+A++L S+ G+ L+ + ++ VSF A E V + +++ +W F RL LL + TL FKV++ DE+ ++G +DL LL GF+ + GWYNI D G+CQGQIKV ++P
Sbjct: 187 FFVEYHFPVGFSKSGLGKTALIT---EVVRLASSKITDGVVKFQQRFVC-------------------PVEF-GGPMIEHWWDSNLIFQIYAKKTPQKKPEVIGSASLPLRAVIQSELLSFSSQLPVQQENGLSSLGPLKVTMELVLGHKDFTGISAKLSSSTQPAPVSAATSSDTILPETGQDTACTRNPQSSNKIHEETTKKTQNLVLPDQESANSVASNSSIFMAVPSCNLVHQINGSNKESGLLLHVLLMVP-----DGKDFVFGEREKQPSCNVYLNCKLFST-EEVTRSVVSWGTAQ----------PVFNFSQVIPVSLTSKCLERLKNNVMIIETWNKVRSPGQDKLLGLVKLPLHQFYMSFKDPKISRLLLDARYPVVAVDSYMPVIDVFSGHQNGSLRVFLAMGSSAQI--MMLQRLKNEEGTLPPFSPRPAHFLDQPPVASVAMP-EKQGTRLMEHHFEFCVAMVKGLMPLQATVWGEADCYVQYYFPFQDSQPSVLQGPDFLENGITLKPFRTSTTLCVPDPVFNSEHHHSLLLPTDVPVQRLLLSAFSSQGLVPGGGVQFEVWCRYYYPNVRDQMVAKGTLPLSRVCAMVTMQYREDVGMQSFNLPLTSRLEHSKELKNQSSG-------FLDVGLRYRRSPRTAEGILAARAVS---------ISVHIIRACGLQAAAKALAEQEPALQFSATVGVNASVTAHLS--------------FLPKGEQRQTRPVACSFCPEFSHHIEFPCNLVTQHCSGEACF--LAE--LLEFAEIIFAIYHENTKSV-SDITSIQSCKDYLLGIVKVPTKDLLVKRSGITG--WYPVILP--EDKGL------------PQDLDLMQ--KIVGGLELSVSFAHPGDRERVLEAAELLG----WSFESIPKDLVKKEEEVPA------TVTISTPRLWLPIHCVLLAGHMNIHKNTYCYL-RYKLYNQEAFWTPLRKPKESTNKNQVLITFKASKRAEVTRSQSLLWYFREEKLEIQVWRAYG----------NDNLERPHQTDSWIGSAYVDLSRLGEKSPR-TLTISGVYPLFGRNASDLSGAALRIHVLL----SPLSPHTEPARELDSMDCSSHSESEQHPRKSDALQLSPPHVLQTSPTSTQVHGNSAAAQVCPAQEGPPELAGTFAVSILVERAMHL--------SLKGSPLTDRKVSVPSCCVSFATATELSPVYTHVVENTDSPIWGFHQQARLSKELLLDPHQTLVFKVWHKG----------DEERVVGFASVDLSPLLSGFQFICGWYNITDFSGECQGQIKVAISP 1368
BLAST of C2 domain-containing protein 3 vs. Ensembl Mouse
Match: C2cd3 (C2 calcium-dependent domain containing 3 [Source:MGI Symbol;Acc:MGI:2142166]) HSP 1 Score: 277.33 bits (708), Expect = 3.336e-74 Identity = 336/1321 (25.44%), Postives = 557/1321 (42.17%), Query Frame = 1
Query: 1621 YFIEYKFPTN---------ALYTADKDKENLSNSMSTTRVLVKQTGFKCNISDSNGIKSLSLDHVSEFPVTFTNSAIIQKWWRGIVRFKLICQDS-NKKETVVGVGVVPLRNIISTN--NFYRLIPIRLPRNKSA----KSNTRMVIG-------SXXXXXXXXXXXXKGFNSSDKKPEILFQDSSDSRNQIS--YYHPKXXXXXXXXXXXXXXXXERAN--------FPSQQVSHISRSSIKIPPTSLQSLLYVSSIRYVNPKSTVNGYKSDTKSCNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDLMMSKENTFNGHWNRNYLTNAFSSNELVEHSIEMDIESLGNFLVENYSE---------LPLK-----ESYFYIQYYFPLQNS-ISDNNGKNW-ESAV----FRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFESLG---KKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLIN---QHSVDVDSLAETVTQQ-QLPVRLVNEDHGDSTYPVAVLNIRLCYRTS--VVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDV-RLLGSALFDLSNLILPSDQLNKSVSHILPLWKRGLNNCGNSNITVSMSICGASSPLAGYNSDNEEESNL---------------NATKIPNNHSIQ--------NGNGNFHRLRADHQ-------SFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNY---FVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTP 5295
+F+EY FP AL T + L++S T V+ Q F C PV F +I+ WW + F++ + + KK V+G +PLR +I + +F +P++ S+ K +V+G S L ++ A SSD QD++ +RN S H + T + + PS + H S K L LL V + K V G + SCN+YL +L T E +S + WG + Q V F F + + LTS+ LE+LKNN I+E W+ + L GLVK+P++ F+MSFK+ KI + +L+ YP+++VD ++ + D SG G + V LAMGS QI +M+ + G A ++ S+ M E G L+E++ E +PL+ E+ Y+QYYFP Q+S S G ++ E+ + FR++ + + + H LP D ++ +L F S G + FE++ + Y P + +AKG LPL+ + ++ + V + S +T + + L N+ G L++ L YR S + + + ++ I + +I A GLQ AA++L P LQ+ + GVN V L+ + K + + T+ + +F P+F E + + + LAE L ++ +YH S+ SDIT + L+G ++ DLL++ SG G W P+ P D GL + L ++ K VG +E+ + F DR+ +L+ A G W+ +DLV + + TV I L + + + K++ L RY+++ Q +P E ++ I ++ S L Y RE KLEIQ W YG ND+ E P+ +GSA DLS L S + ++S + PL+ R ++ + + + + + SPL+ + E ++ +A ++ H +Q +GN ++ + +F V ++VE+A++L S+ G+ L+ + ++ VSF A E V + +++ +W F RL LL + TL FKV++ DE+ ++G +DL LL GF+ + GWYNI D G+CQGQIKV ++P
Sbjct: 564 FFVEYHFPVGFSKSGLGKTALIT---EVVRLASSKITDGVVKFQQRFVC-------------------PVEF-GGPMIEHWWDSNLIFQIYAKKTPQKKPEVIGSASLPLRAVIQSELLSFSSQLPVQQENGLSSLGPLKVTMELVLGHKDFTGISAKLSSSTQPAPVSAATSSDTILPETGQDTACTRNPQSSNKIHEETTKKTQNLVLPDQESANSVASNSSIFMAVPSCNLVHQINGSNKESGLLLHVLLMVP-----DGKDFVFGEREKQPSCNVYLNCKLFST-EEVTRSVVSWGTA-----QPV-----FNFSQVIPVSLTSKCLERLKNNVMIIETWNKVRSPGQDKLLGLVKLPLHQFYMSFKDPKISRLLLDARYPVVAVDSYMPVIDVFSGHQNGSLRVFLAMGSSAQI--MMLQRLKNEEGTLPPFSPRPAHFLDQPPVASVAMP-EKQGTRLMEHHFEFCVAMVKGLMPLQATVWGEADCYVQYYFPFQDSQPSVLQGPDFLENGITLKPFRTSTTLCVPDPVFNSEHHHSLLLPTDVPVQRLLLSAFSSQGLVPGGGVQFEVWCRYYYPNVRDQMVAKGTLPLSRVCAMVTMQYREDVGMQSFNLPLTSRLEHSKELKNQSSG-------FLDVGLRYRRSPRTAEGILAARAVS---------ISVHIIRACGLQAAAKALAEQEPALQFSATVGVNASVTAHLS--------------FLPKGEQRQTRPVACSFCPEFSHHIEFPCNLVTQHCSGEACF--LAE--LLEFAEIIFAIYHENTKSV-SDITSIQSCKDYLLGIVKVPTKDLLVKRSGITG--WYPVILP--EDKGL------------PQDLDLMQ--KIVGGLELSVSFAHPGDRERVLEAAELLG----WSFESIPKDLVKKEEEVPA------TVTISTPRLWLPIHCVLLAGHMNIHKNTYCYL-RYKLYNQEAFWTPLRKPKESTNKNQVLITFKASKRAEVTRSQSLLWYFREEKLEIQVWRAYG----------NDNLERPHQTDSWIGSAYVDLSRLGEKSPR-TLTISGVYPLFGRNASDLSGAALRIHVLL----SPLSPHTEPARELDSMDCSSHSESEQHPRKSDALQLSPPHVLQTSPTSTQVHGNSAAAQVCPAQEGPPELAGTFAVSILVERAMHL--------SLKGSPLTDRKVSVPSCCVSFATATELSPVYTHVVENTDSPIWGFHQQARLSKELLLDPHQTLVFKVWHKG----------DEERVVGFASVDLSPLLSGFQFICGWYNITDFSGECQGQIKVAISP 1745 HSP 2 Score: 91.2781 bits (225), Expect = 1.729e-17 Identity = 59/188 (31.38%), Postives = 99/188 (52.66%), Query Frame = 1
Query: 46 NTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLEP-TQLHKTLEKTYVKPIITNELNEKAELRTSLNKSH-ESMKP 603
+TSLPP + + + +L L IN + W K++ ++V+V WWGE S+G +F PR L + V+T Y +R FT+YL+DM+ L +++I K H +GR I L QL + I++ K+GE+ + + LEP ++ + + + + N L + ELR + S+ +SM P
Sbjct: 26 STSLPPLV-EGQLRCFLKLTINKVVW--KIAKPPTSVLVRVRWWGETSDGTLFCPRDA-LQTEPKAVRTTTRYGIRCGPKQFTSYLTDMAVLVLEVITKFDHLPVGRVQISGLAQLSPTHQINGFFTIVSPASKKLGELQVSLALEPLSETYDSYKPLPATEVTKNVLLSERELRENTESSNTQSMIP 209
BLAST of C2 domain-containing protein 3 vs. Ensembl Mouse
Match: C2cd3 (C2 calcium-dependent domain containing 3 [Source:MGI Symbol;Acc:MGI:2142166]) HSP 1 Score: 277.33 bits (708), Expect = 4.054e-74 Identity = 336/1321 (25.44%), Postives = 557/1321 (42.17%), Query Frame = 1
Query: 1621 YFIEYKFPTN---------ALYTADKDKENLSNSMSTTRVLVKQTGFKCNISDSNGIKSLSLDHVSEFPVTFTNSAIIQKWWRGIVRFKLICQDS-NKKETVVGVGVVPLRNIISTN--NFYRLIPIRLPRNKSA----KSNTRMVIG-------SXXXXXXXXXXXXKGFNSSDKKPEILFQDSSDSRNQIS--YYHPKXXXXXXXXXXXXXXXXERAN--------FPSQQVSHISRSSIKIPPTSLQSLLYVSSIRYVNPKSTVNGYKSDTKSCNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDLMMSKENTFNGHWNRNYLTNAFSSNELVEHSIEMDIESLGNFLVENYSE---------LPLK-----ESYFYIQYYFPLQNS-ISDNNGKNW-ESAV----FRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFESLG---KKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLIN---QHSVDVDSLAETVTQQ-QLPVRLVNEDHGDSTYPVAVLNIRLCYRTS--VVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDV-RLLGSALFDLSNLILPSDQLNKSVSHILPLWKRGLNNCGNSNITVSMSICGASSPLAGYNSDNEEESNL---------------NATKIPNNHSIQ--------NGNGNFHRLRADHQ-------SFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNY---FVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTP 5295
+F+EY FP AL T + L++S T V+ Q F C PV F +I+ WW + F++ + + KK V+G +PLR +I + +F +P++ S+ K +V+G S L ++ A SSD QD++ +RN S H + T + + PS + H S K L LL V + K V G + SCN+YL +L T E +S + WG + Q V F F + + LTS+ LE+LKNN I+E W+ + L GLVK+P++ F+MSFK+ KI + +L+ YP+++VD ++ + D SG G + V LAMGS QI +M+ + G A ++ S+ M E G L+E++ E +PL+ E+ Y+QYYFP Q+S S G ++ E+ + FR++ + + + H LP D ++ +L F S G + FE++ + Y P + +AKG LPL+ + ++ + V + S +T + + L N+ G L++ L YR S + + + ++ I + +I A GLQ AA++L P LQ+ + GVN V L+ + K + + T+ + +F P+F E + + + LAE L ++ +YH S+ SDIT + L+G ++ DLL++ SG G W P+ P D GL + L ++ K VG +E+ + F DR+ +L+ A G W+ +DLV + + TV I L + + + K++ L RY+++ Q +P E ++ I ++ S L Y RE KLEIQ W YG ND+ E P+ +GSA DLS L S + ++S + PL+ R ++ + + + + + SPL+ + E ++ +A ++ H +Q +GN ++ + +F V ++VE+A++L S+ G+ L+ + ++ VSF A E V + +++ +W F RL LL + TL FKV++ DE+ ++G +DL LL GF+ + GWYNI D G+CQGQIKV ++P
Sbjct: 564 FFVEYHFPVGFSKSGLGKTALIT---EVVRLASSKITDGVVKFQQRFVC-------------------PVEF-GGPMIEHWWDSNLIFQIYAKKTPQKKPEVIGSASLPLRAVIQSELLSFSSQLPVQQENGLSSLGPLKVTMELVLGHKDFTGISAKLSSSTQPAPVSAATSSDTILPETGQDTACTRNPQSSNKIHEETTKKTQNLVLPDQESANSVASNSSIFMAVPSCNLVHQINGSNKESGLLLHVLLMVP-----DGKDFVFGEREKQPSCNVYLNCKLFST-EEVTRSVVSWGTA-----QPV-----FNFSQVIPVSLTSKCLERLKNNVMIIETWNKVRSPGQDKLLGLVKLPLHQFYMSFKDPKISRLLLDARYPVVAVDSYMPVIDVFSGHQNGSLRVFLAMGSSAQI--MMLQRLKNEEGTLPPFSPRPAHFLDQPPVASVAMP-EKQGTRLMEHHFEFCVAMVKGLMPLQATVWGEADCYVQYYFPFQDSQPSVLQGPDFLENGITLKPFRTSTTLCVPDPVFNSEHHHSLLLPTDVPVQRLLLSAFSSQGLVPGGGVQFEVWCRYYYPNVRDQMVAKGTLPLSRVCAMVTMQYREDVGMQSFNLPLTSRLEHSKELKNQSSG-------FLDVGLRYRRSPRTAEGILAARAVS---------ISVHIIRACGLQAAAKALAEQEPALQFSATVGVNASVTAHLS--------------FLPKGEQRQTRPVACSFCPEFSHHIEFPCNLVTQHCSGEACF--LAE--LLEFAEIIFAIYHENTKSV-SDITSIQSCKDYLLGIVKVPTKDLLVKRSGITG--WYPVILP--EDKGL------------PQDLDLMQ--KIVGGLELSVSFAHPGDRERVLEAAELLG----WSFESIPKDLVKKEEEVPA------TVTISTPRLWLPIHCVLLAGHMNIHKNTYCYL-RYKLYNQEAFWTPLRKPKESTNKNQVLITFKASKRAEVTRSQSLLWYFREEKLEIQVWRAYG----------NDNLERPHQTDSWIGSAYVDLSRLGEKSPR-TLTISGVYPLFGRNASDLSGAALRIHVLL----SPLSPHTEPARELDSMDCSSHSESEQHPRKSDALQLSPPHVLQTSPTSTQVHGNSAAAQVCPAQEGPPELAGTFAVSILVERAMHL--------SLKGSPLTDRKVSVPSCCVSFATATELSPVYTHVVENTDSPIWGFHQQARLSKELLLDPHQTLVFKVWHKG----------DEERVVGFASVDLSPLLSGFQFICGWYNITDFSGECQGQIKVAISP 1745 HSP 2 Score: 90.8929 bits (224), Expect = 2.084e-17 Identity = 59/188 (31.38%), Postives = 99/188 (52.66%), Query Frame = 1
Query: 46 NTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLEP-TQLHKTLEKTYVKPIITNELNEKAELRTSLNKSH-ESMKP 603
+TSLPP + + + +L L IN + W K++ ++V+V WWGE S+G +F PR L + V+T Y +R FT+YL+DM+ L +++I K H +GR I L QL + I++ K+GE+ + + LEP ++ + + + + N L + ELR + S+ +SM P
Sbjct: 26 STSLPPLV-EGQLRCFLKLTINKVVW--KIAKPPTSVLVRVRWWGETSDGTLFCPRDA-LQTEPKAVRTTTRYGIRCGPKQFTSYLTDMAVLVLEVITKFDHLPVGRVQISGLAQLSPTHQINGFFTIVSPASKKLGELQVSLALEPLSETYDSYKPLPATEVTKNVLLSERELRENTESSNTQSMIP 209
BLAST of C2 domain-containing protein 3 vs. Ensembl Mouse
Match: C2cd3 (C2 calcium-dependent domain containing 3 [Source:MGI Symbol;Acc:MGI:2142166]) HSP 1 Score: 136.346 bits (342), Expect = 1.628e-31 Identity = 136/529 (25.71%), Postives = 227/529 (42.91%), Query Frame = 1
Query: 3811 VYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDV-RLLGSALFDLSNLILPSDQLNKSVSHILPLWKRGLNNCGNSNITVSMSICGASSPLAGYNSDNEEESNLN---------------ATKIPNNHSIQ--------NGNGNFHRLRADHQ-------SFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNY---FVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTP 5295
+YH S+ SDIT + L+G ++ DLL++ SG G W P+ P D GL + L ++K VG +E+ + F DR+ +L+ A G W+ +DLV + + TV I L + + + K++ L RY+++ Q +P E ++ I ++ S L Y RE KLEIQ W YG ND+ E P+ +GSA DLS L S + ++S + PL+ R ++ + + + + + SPL+ + E +++ A ++ H +Q +GN ++ + +F V ++VE+A++L S+ G+ L+ + ++ VSF A E V + +++ +W F RL LL + TL FKV++ DE+ ++G +DL LL GF+ + GWYNI D G+CQGQIKV ++P
Sbjct: 49 IYHENTKSV-SDITSIQSCKDYLLGIVKVPTKDLLVKRSGITG--WYPVILP--EDKGL------------PQDLDLMQK--IVGGLELSVSFAHPGDRERVLEAAELLG----WSFESIPKDLVKKEEEVPA------TVTISTPRLWLPIHCVLLAGHMNIHKNTYCYL-RYKLYNQEAFWTPLRKPKESTNKNQVLITFKASKRAEVTRSQSLLWYFREEKLEIQVWRAYG----------NDNLERPHQTDSWIGSAYVDLSRLGEKSPR-TLTISGVYPLFGRNASDLSGAALRIHVLL----SPLSPHTEPARELDSMDCSSHSESEQHPRKSDALQLSPPHVLQTSPTSTQVHGNSAAAQVCPAQEGPPELAGTFAVSILVERAMHL--------SLKGSPLTDRKVSVPSCCVSFATATELSPVYTHVVENTDSPIWGFHQQARLSKELLLDPHQTLVFKVWHKG----------DEERVVGFASVDLSPLLSGFQFICGWYNITDFSGECQGQIKVAISP 514
BLAST of C2 domain-containing protein 3 vs. Ensembl Mouse
Match: C2cd3 (C2 calcium-dependent domain containing 3 [Source:MGI Symbol;Acc:MGI:2142166]) HSP 1 Score: 85.1149 bits (209), Expect = 2.637e-17 Identity = 48/139 (34.53%), Postives = 73/139 (52.52%), Query Frame = 1
Query: 46 NTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEI 462
+TSLPP + F L L IN + W K++ ++V+V WWGE S+G +F PR L + V+T Y +R FT+YL+DM+ L +++I K H +GR I L QL + I++ K+GE+
Sbjct: 26 STSLPPLVEGQLRCF-LKLTINKVVW--KIAKPPTSVLVRVRWWGETSDGTLFCPR-DALQTEPKAVRTTTRYGIRCGPKQFTSYLTDMAVLVLEVITKFDHLPVGRVQISGLAQLSPTHQINGFFTIVSPASKKLGEL 160
BLAST of C2 domain-containing protein 3 vs. UniProt/SwissProt
Match: sp|Q4AC94|C2CD3_HUMAN (C2 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=C2CD3 PE=1 SV=4) HSP 1 Score: 280.026 bits (715), Expect = 4.436e-74 Identity = 285/1066 (26.74%), Postives = 464/1066 (43.53%), Query Frame = 1
Query: 2311 KSTVNGYKSDTKSCNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDL--MMSKENTFNGHWNR--NYLTNAFSS---------NELVEHSIEMDIESLGNFLVENYSELPLK---ESYFYIQYYFPLQNSISD--------NNGKNWESAVFRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFESLG---KKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLIN-QHSVDVDSLAETVTQQQLPVRLVNEDHGD-STYPVAVLNIRLCYRTS--VVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLG-GLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDV-RLLGSALFDLSNLILPSDQLNKSVSHILPLWKRGLNNCGNSNITVSMSICGASSPL----------AGYNSDNEEESNLN-------------------ATKIPNNHS------IQNGNGNFHRLRADHQSFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNY---FVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTP 5295
K ++G CN+YL +L T E +S I WG + Q V F F + + L+S+ LE+LKNN ++E W+ + L GLVK+P++ F+MSFK+ KI + +L+ YP+++VD ++ + D SG G + V LAMGS QI L + ++E T R ++L ++ N L+EH E+ IE +V+ + L E+ Y+QYYFP+Q+S S NG + FR+A + + + H LP + ++ +L F + G + FE++ + Y P + +AKG LPL+ + ++ QH DV + LP+ E+ + +L++ L YR S + + +T++ I +++I A GLQ AA++L P LQ+ + GVN V L+ + R T + +F P+F E + + + LAE L ++ VYH S SDI + + L+G ++ +LL++ SG G W PI P D GL GL+L +K VG +E+ + F + DR+ +L+ A G W+ +D V MD + TV I L + + K++ L RY+ + +P E +I + ++ L Y RE +LEIQ W YG ND E P+ +GSA DL+ L S + +VS + PL+ R +N + + V + + SS L +S++E+ N +T++P + + Q G + +F V ++VE+A++L S+ G+ L+ + ++ VSF A+E V + +++ +WNF+ +RL LL + + TL FKV++ DE+ +IG +DL LL GF+ V GWYNI D G+CQGQIKV V+P
Sbjct: 815 KDFISGESEKQSPCNVYLNCKLFST-EEVTRSVIAWGTT-----QPV-----FNFSQVIPVSLSSKYLERLKNNVMVIETWNKVRSPGQDKLLGLVKLPLHQFYMSFKDAKISRLLLDAQYPVVAVDSYMPVIDVFSGHQNGSLRVFLAMGSSNQIMALQRLKNEEGTLPPFSPRPAHFLDQPTAASVAMAEDRGNGLMEHCFEIHIE-----MVKGLAPLQATVWGEADCYVQYYFPVQHSQSSVLKGPEFLENGITLKP--FRTATTLCVPDPIFNSEHHHSLLLPAEVPVQRLLLSAFSAQGLVPGGGVQFEIWCRYYYPNVRDQKVAKGTLPLSRICAMVTTQHREDVG-----IQTFNLPLTPRIENRKELRNQSSGLLDVGLRYRRSPRTAEGVLAARTVS---------ISVQIIRACGLQAAAKALAEREPALQFSATVGVNASVTTHLSFLPQGEQR--------------RTHPVACSFCPEFSHHVEFTCNLVTQHCSGEACF--LAE--LLEFAEVIFAVYHENTKSA-SDIISIESCKEYLLGVVKVPTKELLIKRSGITG--WYPIILP--EDGGLPHGLEL---------------MQKIVGGLELSISFTHRGDRERVLEAAEHLG----WSFENSLKDFV--RMDEG----EPATVTISTPRLWLPIHCVLLAGHNHIHKNTYCYL-RYKFYDHEAFWTPLKKPKESVNKKQIMVTFKASKRAEVTRGPSLLWYFREERLEIQVWRAYG----------NDSVERPHQTDSWIGSAYVDLARLGERSAR-TLTVSGVYPLFGRNASNLSGAALRVHVVLSSLSSHLEPTHELDSMDCSSHSESEQLPRRNDEVQLSPPEVISCHQKSPASTQVPCSSTTAEVRLTQEGPADL------DGTFAVSILVERAMHL--------SLKGSPLTERKVSIPSCCVSFATADESSPVYTQVVENTDSPIWNFQQQSRLSKELLLDPQQTLVFKVWHKG----------DEERVIGFASVDLSPLLSGFQFVCGWYNITDFSGECQGQIKVAVSP 1764 HSP 2 Score: 92.8189 bits (229), Expect = 3.971e-17 Identity = 55/171 (32.16%), Postives = 90/171 (52.63%), Query Frame = 1
Query: 46 NTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLEPTQLHKTLEKTY--VKPIITNELNE 552
+TSLPP + + + +L L +N + W K++ ++V+V WWGE S+G +F PR L + V+T Y +R FT+YL+DM+ L +++I K IGR I+ L QL + I++ K+GE+ + + LEP L +TY P+ T ++ E
Sbjct: 26 STSLPPLV-EGQLRCFLKLTVNRVIW--KIAKPPTCVLVRVRWWGETSDGTLFCPRDA-LQTEPKAVRTTTRYAIRCGPKQFTSYLTDMAVLVLEVITKLDGLPIGRVQINGLAQLSPTHQINGFFTIVSSTSKKLGELQVSLALEP------LSETYDSYHPLPTTDMTE 186
BLAST of C2 domain-containing protein 3 vs. UniProt/SwissProt
Match: sp|Q52KB6|C2CD3_MOUSE (C2 domain-containing protein 3 OS=Mus musculus OX=10090 GN=C2cd3 PE=1 SV=3) HSP 1 Score: 277.33 bits (708), Expect = 2.836e-73 Identity = 336/1321 (25.44%), Postives = 557/1321 (42.17%), Query Frame = 1
Query: 1621 YFIEYKFPTN---------ALYTADKDKENLSNSMSTTRVLVKQTGFKCNISDSNGIKSLSLDHVSEFPVTFTNSAIIQKWWRGIVRFKLICQDS-NKKETVVGVGVVPLRNIISTN--NFYRLIPIRLPRNKSA----KSNTRMVIG-------SXXXXXXXXXXXXKGFNSSDKKPEILFQDSSDSRNQIS--YYHPKXXXXXXXXXXXXXXXXERAN--------FPSQQVSHISRSSIKIPPTSLQSLLYVSSIRYVNPKSTVNGYKSDTKSCNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDLMMSKENTFNGHWNRNYLTNAFSSNELVEHSIEMDIESLGNFLVENYSE---------LPLK-----ESYFYIQYYFPLQNS-ISDNNGKNW-ESAV----FRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFESLG---KKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLIN---QHSVDVDSLAETVTQQ-QLPVRLVNEDHGDSTYPVAVLNIRLCYRTS--VVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDV-RLLGSALFDLSNLILPSDQLNKSVSHILPLWKRGLNNCGNSNITVSMSICGASSPLAGYNSDNEEESNL---------------NATKIPNNHSIQ--------NGNGNFHRLRADHQ-------SFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNY---FVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTP 5295
+F+EY FP AL T + L++S T V+ Q F C PV F +I+ WW + F++ + + KK V+G +PLR +I + +F +P++ S+ K +V+G S L ++ A SSD QD++ +RN S H + T + + PS + H S K L LL V + K V G + SCN+YL +L T E +S + WG + Q V F F + + LTS+ LE+LKNN I+E W+ + L GLVK+P++ F+MSFK+ KI + +L+ YP+++VD ++ + D SG G + V LAMGS QI +M+ + G A ++ S+ M E G L+E++ E +PL+ E+ Y+QYYFP Q+S S G ++ E+ + FR++ + + + H LP D ++ +L F S G + FE++ + Y P + +AKG LPL+ + ++ + V + S +T + + L N+ G L++ L YR S + + + ++ I + +I A GLQ AA++L P LQ+ + GVN V L+ + K + + T+ + +F P+F E + + + LAE L ++ +YH S+ SDIT + L+G ++ DLL++ SG G W P+ P D GL + L ++ K VG +E+ + F DR+ +L+ A G W+ +DLV + + TV I L + + + K++ L RY+++ Q +P E ++ I ++ S L Y RE KLEIQ W YG ND+ E P+ +GSA DLS L S + ++S + PL+ R ++ + + + + + SPL+ + E ++ +A ++ H +Q +GN ++ + +F V ++VE+A++L S+ G+ L+ + ++ VSF A E V + +++ +W F RL LL + TL FKV++ DE+ ++G +DL LL GF+ + GWYNI D G+CQGQIKV ++P
Sbjct: 564 FFVEYHFPVGFSKSGLGKTALIT---EVVRLASSKITDGVVKFQQRFVC-------------------PVEF-GGPMIEHWWDSNLIFQIYAKKTPQKKPEVIGSASLPLRAVIQSELLSFSSQLPVQQENGLSSLGPLKVTMELVLGHKDFTGISAKLSSSTQPAPVSAATSSDTILPETGQDTACTRNPQSSNKIHEETTKKTQNLVLPDQESANSVASNSSIFMAVPSCNLVHQINGSNKESGLLLHVLLMVP-----DGKDFVFGEREKQPSCNVYLNCKLFST-EEVTRSVVSWGTA-----QPV-----FNFSQVIPVSLTSKCLERLKNNVMIIETWNKVRSPGQDKLLGLVKLPLHQFYMSFKDPKISRLLLDARYPVVAVDSYMPVIDVFSGHQNGSLRVFLAMGSSAQI--MMLQRLKNEEGTLPPFSPRPAHFLDQPPVASVAMP-EKQGTRLMEHHFEFCVAMVKGLMPLQATVWGEADCYVQYYFPFQDSQPSVLQGPDFLENGITLKPFRTSTTLCVPDPVFNSEHHHSLLLPTDVPVQRLLLSAFSSQGLVPGGGVQFEVWCRYYYPNVRDQMVAKGTLPLSRVCAMVTMQYREDVGMQSFNLPLTSRLEHSKELKNQSSG-------FLDVGLRYRRSPRTAEGILAARAVS---------ISVHIIRACGLQAAAKALAEQEPALQFSATVGVNASVTAHLS--------------FLPKGEQRQTRPVACSFCPEFSHHIEFPCNLVTQHCSGEACF--LAE--LLEFAEIIFAIYHENTKSV-SDITSIQSCKDYLLGIVKVPTKDLLVKRSGITG--WYPVILP--EDKGL------------PQDLDLMQ--KIVGGLELSVSFAHPGDRERVLEAAELLG----WSFESIPKDLVKKEEEVPA------TVTISTPRLWLPIHCVLLAGHMNIHKNTYCYL-RYKLYNQEAFWTPLRKPKESTNKNQVLITFKASKRAEVTRSQSLLWYFREEKLEIQVWRAYG----------NDNLERPHQTDSWIGSAYVDLSRLGEKSPR-TLTISGVYPLFGRNASDLSGAALRIHVLL----SPLSPHTEPARELDSMDCSSHSESEQHPRKSDALQLSPPHVLQTSPTSTQVHGNSAAAQVCPAQEGPPELAGTFAVSILVERAMHL--------SLKGSPLTDRKVSVPSCCVSFATATELSPVYTHVVENTDSPIWGFHQQARLSKELLLDPHQTLVFKVWHKG----------DEERVVGFASVDLSPLLSGFQFICGWYNITDFSGECQGQIKVAISP 1745 HSP 2 Score: 90.8929 bits (224), Expect = 1.458e-16 Identity = 59/188 (31.38%), Postives = 99/188 (52.66%), Query Frame = 1
Query: 46 NTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLEP-TQLHKTLEKTYVKPIITNELNEKAELRTSLNKSH-ESMKP 603
+TSLPP + + + +L L IN + W K++ ++V+V WWGE S+G +F PR L + V+T Y +R FT+YL+DM+ L +++I K H +GR I L QL + I++ K+GE+ + + LEP ++ + + + + N L + ELR + S+ +SM P
Sbjct: 26 STSLPPLV-EGQLRCFLKLTINKVVW--KIAKPPTSVLVRVRWWGETSDGTLFCPRDA-LQTEPKAVRTTTRYGIRCGPKQFTSYLTDMAVLVLEVITKFDHLPVGRVQISGLAQLSPTHQINGFFTIVSPASKKLGELQVSLALEPLSETYDSYKPLPATEVTKNVLLSERELRENTESSNTQSMIP 209
BLAST of C2 domain-containing protein 3 vs. UniProt/SwissProt
Match: sp|A0JM13|C2CD3_XENTR (C2 domain-containing protein 3 OS=Xenopus tropicalis OX=8364 GN=c2cd3 PE=2 SV=2) HSP 1 Score: 273.092 bits (697), Expect = 6.298e-72 Identity = 272/1043 (26.08%), Postives = 466/1043 (44.68%), Query Frame = 1
Query: 2350 CNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDL--MMSKENTFNGHWNR--NYLTNAFSSNE-------LVEHSIEMDIESLGNFLVENYSELPLK-----ESYFYIQYYFPLQNSISDNNGKNWESAV----FRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFESL---GKKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLIN-QHSVDVDSLAETVTQQQLPVRLVNEDHGD-STYPVAVLNIRLCYRTSVVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSG---YVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSP--NFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDV-RLLGSALFDLSNLILPSDQLNK--SVSHILPLWKRGLNNCGNSNITVSMSICGASSP--------LAGYNSDNEEE----SNLNATKIPNNHSIQN----GNGNFHRLRADHQ---------SFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPL---NYFVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTP 5295
CN YL +L ++A E +S ++WG+++ + F + L L + LLE++KNN I+E+W+ + L GL K+P++ F+MSF + KI + +L YP+++VD ++ I D SG +G++ VLLA+GS Q+ L + ++E T R ++L SS++ + +H E+ +E++ PL+ E+ ++QYYFP S E A+ R+A + +D H D+ ++ +L + G + FE++ + Y P + +AKG LPL+ L ++ QH DV A + LP+ +E + P +LN+ + YR S ++N V +S I +++ A+GLQ AA + QY + GVN +V ++ + + ++T+T+ RTF P+FD E +I N +LAE + ++ + ++H S+ S T P +G RI L+ + SG G W P+ P +S KL ++ L+++ VG +E+ + F SDR +L++A G Y + + TE W ++ ++V+I +I L L + KS+ L RY+ + + SP ++ED I ++ ++ L YLRE ++EIQ W YG + + P D RL+G A DL L S+ ++ +VS + PL+KR +++ + + V +++ A P AG S +E E ++ ++ + + S +N L A Q +F ++VE+A++L S+ GT L+ + VS+P A + VT+ +I +WNF+ RL LL + + L FKV++ D + ++G +DL LL GF+ + GWYNIVD G CQGQ+KV +TP
Sbjct: 797 CNSYLNCKL-FSAQEATRSSVVWGSTQ----------PQYNFSQVAPLTLNARLLERMKNNVMIIEIWNRVASPGQDQLLGLAKLPLHQFYMSFSDPKITRLLLQAQYPVVAVDSYVPIIDVFSGCDRGKLKVLLAIGSGDQVVALQRLKNEEGTSQTAMPRPAHFLDPPLSSSQMGRPQEGMTDHIFEIHVENVKGL-------TPLQSTVWGEADCFVQYYFPAHGPDSHTAIDLPEIAMTLKPVRTATTLCVPDPVFNDRQSHTIVAQSDTPVQRLLLGAYSMQGLSGGGGVPFEIWCRYYYPNVRDQMVAKGVLPLSRLCAMVTMQHREDVGIQAFS-----LPLIPRSEKSAELPPQPSGLLNVNVTYRRS-MRNPVGMLATRMAS------ISVQIHRASGLQAAARLVAQQDASFQYSADVGVNAYVT--------------IHPAFLPDVELRNTRTVARTFCPEFDHHYEFPCNMVIQRNNGEAC--SLAEVLY--FSEIVLSIHHQNVASVGS--TRPQPVRDYHLGMVRIPCRQLITKRSGVSG--WYPVTVPEDS-------KL----PTDSTILHSV-----VGGLELSVHFAHHSDRDRVLEVARGLGWNEYNEDFQEAIATEADEWHKRED----LVNLSVNIPKIWL--PLHCLLLAGHKHIHKSTYCYL-RYKFYDREAVCSPLRRPRLSEDGQQATIMFELSENRELIKH--QPLVWYLREERMEIQVWRSYGKDT---------NGPRPQDTDRLIGCAYVDLKAL---SENTSRTLAVSGVYPLFKRNVSSLWGAAVRVHLALSSAYHPSNSSRRLSCAGERSQSEGEEWAPTSGDSFEEKQDDSAKNDKPEAKTEVPLLDAKEQPVGEVDLKNTFAASIVVERAMHL--------SLKGTPLTERAAATPTCCVSYPVAGCSEPVTTPVIANTDSPLWNFQHQARLHKELLLDPQQRLVFKVWHKT----------DVERVVGFASVDLSPLLSGFQSICGWYNIVDFVGQCQGQVKVSITP 1732 HSP 2 Score: 77.411 bits (189), Expect = 1.563e-12 Identity = 49/151 (32.45%), Postives = 78/151 (51.66%), Query Frame = 1
Query: 34 NVVVNTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLEP 486
+V +TSLPP + + + +L + ++ I W V ++V++ WWGE +NG +F PR + K KT Y VR FT+YL+DM L +++ K H IGRA I + QL + I++ K+GE+ + + LEP
Sbjct: 21 DVTPSTSLPPLV-EGQVRSFLQVTVSKILW--TVPKPPPSVLVRLRWWGETANGTVFRPRDSSQTEQK-GAKTTTRYAVRCGPKQFTSYLTDMGMLVFEVMTKLDHFPIGRAQISGIAQLSLAHPVSGFFTIVSPTSEKLGELQVSVQLEP 167
BLAST of C2 domain-containing protein 3 vs. TrEMBL
Match: A0A1S3H009 (C2 domain-containing protein 3-like OS=Lingula unguis OX=7574 GN=LOC106150507 PE=4 SV=1) HSP 1 Score: 311.612 bits (797), Expect = 3.286e-81 Identity = 284/1102 (25.77%), Postives = 480/1102 (43.56%), Query Frame = 1
Query: 2314 STVNGYKSDTKSCNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDLMMSKENTFNG----------HWNRNYLTNAFSSNE---------LVEHSIEMDIESLGNFLVENYSELPLKESYFYIQYYFPLQNSISDNNGKNWESAV-----FRSANCQVERNVDISDTNRHRFRLPIDSSLKA--ILNKHFESLGKKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLINQHSVDVDSLAETVTQQQLPVRLVNEDHGDSTYP--------VAVLNIRLCYRTSVVQNAVRQK--TLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGV------FDS--IYSDITEV------PPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEK---------RKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQS--ISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIY-GSEARCNNDYLNDHNENPNDVRLLGSALFDLSNLILPSDQLNKS--VSHILPLWKRGLNNCGNSNITVSMSICGASSPLAGYNSDNEEE-------SNLNATKIPNNHSIQNGNGNFHR-----------LRADHQSFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNYFVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTPTIPLVPNTAVLSKVSSSVYSPPTKPL 5373
ST+ D + NLYL+ R+ W + S + WG F FV+ +++T LLE+++NNF +LEVWD T L G+VK+ ++ F+MSF++ KI + +L + YP++SVD+W+ ++DP +G GQ+ VLLA+GS +Q+ L K + NG + R ++ SS LVEH E IE + + + ++ E+ +IQY+FP Q + AV FR+A + + RHR LP + ++ + G + E++ + Y P + IAK LPL L ++ S V LP+ + D D+ P +L + + Y+T+ ++ + +K T + + Q I + ++ A+GL+ AA ++ +QYP+ GVN +V+ L+ S + RI T+T+ RTF P+F + + +E+S+ L LAE + ++ E++H V D +Y+ EV + +L+G I + LL +G G W P+ P L W K + + A + + VG +EV L F DR ++ A G W + ED W+ D + ++TVH++ L NA+ + K++ + RY+ F ++ +S ++E+ G I VNH+ S YL+E +LE+Q W Y G + D +L+G A DL +L +D+ + VS + PL+K G+++ G + + +++ A ++EEE N + +P + + G H+ + D SF H+ +E+A++L + TG P N +V++ A + ++++ +W + DTRL LL E L FKV++ + + + ++VL G V +DL LL G +++ GWYNI+D G CQGQIKV V P L P + K + + P KP
Sbjct: 909 STLGWTGRDMATRNLYLVCRMFW-CDDAVTSSVCWGTFNPV----------FNFVQIGPVLVTQYLLERMRNNFMVLEVWDKKTGAQNDKLVGIVKLSLHQFYMSFRDRKICRALLKSQYPVVSVDNWLPVQDPFTGIQFGQLKVLLAVGSAEQVSALQRLKLDK-NGDSSMPQRPQHYLERQHVVGDVSSRRPEDYPPTEVLVEHVFEFVIEGVKGLKL--FDDMIWGEADCFIQYHFPAQQQTKQPGVPAIQYAVPTLKPFRTATTLCIPDPTFHEVTRHRILLPEGTPVQRELVTACAGAGGGGGGVPIEVWCRYYYPNVRDQVIAKAVLPLAKLCAMVTMQKRGEPS----VQTFSLPLTTLAGD-SDNLGPEERAKLKEAGLLEVTVHYKTNTLKASPEEKYGTASHAVASAQVCISVGIVRASGLKAAAVAVARHDDGMQYPAEVGVNAYVRTRLSFLSKQDERI--------------TRTVARTFAPEFSYFMDFPCPLLWTEEDSDAL--CLAE--ILETAEVTFEMWHQVPGLSPDLDGQYVYTGSAEVTGRKLFTKTGDVLLGTTTIPLLYLLTHKTGLHG--WYPVHLP----------SLGWAKKAGKDEVQADDSSPHHGNKGLERVVGGLEVSLRFAHHDDRGRVIHAARGVG----WAPEYDLED-DWESADESSDSINHVTVHLDMGAFP--LTNALIAGQTKLDKNA-RCYVRYKFFDKAATLSRLSPLTVHEE---GYIVSAVNHQHNLNISRSAPFLWYLKEERLEVQLWVSYSGKDGERAKPRHRD--------KLIGCAYIDLESL---ADRRRRQHRVSGMYPLFKPGVSSLGGAFLRAHVTLKPA---FGRMEQESEEEVTFASSDENSDVEMLPRSRHGKEKEGGAHKKQKYKDEEEDIIPPDKHSFAAHISIERALHLPVVTDKHSHETG------PPNSYVAYQTAEKTVPSHTNVVPSTGCPLWEHQHDTRLSKDLLYGESKHLVFKVWHKPKAASQSPDKSVDRVL-GFVSVDLSPLLHGLKQICGWYNIMDFSGQCQGQIKVSVVPQEILQP----IEKSAPEEKTTPKKPF 1925 HSP 2 Score: 76.6406 bits (187), Expect = 9.664e-10 Identity = 56/190 (29.47%), Postives = 94/190 (49.47%), Query Frame = 1
Query: 37 VVVNTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNV-KTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLEPTQLHKTLEKTYVKPIITNELNEKAELRTSLNKSHESMKP 603
V V TSLPP + + + +L L +N I W+ V+V WWGE+ GA+F P +N+ G + + KT A Y +R T YL+DM L ++++ + +++G+A ID ++ L K + +++ D KI E+ + ++LE TL TY + EL ++ H+S P
Sbjct: 23 VPVYTSLPPMV-EGQLRCFLRLSVNQILWLLPTPPELSQ--VRVKWWGEEGLGAVFRP--LNVKGSDKTLLKTTARYAIRSGPKQLTAYLTDMGPLVLEVLSGVEMTLVGQAQIDHINTLSPVKPINGFFPVMSANDEKIAELQVSLSLE------TLTGTYDSSGSVPTTDMSTEL--PFHQDHQSAAP 199
BLAST of C2 domain-containing protein 3 vs. TrEMBL
Match: A0A2C9L6N2 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106050191 PE=4 SV=1) HSP 1 Score: 309.686 bits (792), Expect = 8.392e-81 Identity = 308/1210 (25.45%), Postives = 536/1210 (44.30%), Query Frame = 1
Query: 2248 KIPPTSLQSLLYVSSIRYVN-----PKSTVNGYKS---------DTKSCNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDLM------------------MSKENTFNGHWNRNYLTNAFSSNELVEHSIEMDIESLGNF-LVENYSELPLKESYFYIQYYFPLQNSISDNNGKNWES----AVFRSANCQVERNVDISDTNRHRFRLPIDSSL-KAILNKHFESLGKKHIL-FELYLKQYQPFPSSKSIAKGRLPLTSLFQLINQHSVD---VDSLAETVTQQQLPVRLVNEDHGDSTYPVAVLNIRLCYRTSVVQN----AVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKF----DCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITE----------VPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYG-SEARCNNDYLNDHNENPNDVRLLGSALFDLSNLI-LPSDQLNKSVSHILPLWKRGLNNCGNSNITVSMS--ICGASSPLAGYNSDNEEESNLNATKIPNNHSIQNGNGNFHRLRADHQ----------SFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNYFVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTPT----IPLVPNTAVLSKVSSSVYSPPTKPLTVEDHQSYLSSVRMRLLGQTEPLSVYPIPVSVDICPSQDIDSQDL-----------------------VTKSFLFDTLKEKMRELDNLNE 5574
K+ P +L ++L++ R ++ P + + D+ N YL+ R+ W ++ S + WG + F++ +++TS+L+E+L+NNF I+EVWD L G+VK+ ++ F MSF+ KI +L + YP++++D+++ I DP SG GQ+ V+LAMGS QI L + +++ NG N SN+ V+H E+ IE + + L EN + E+ ++Q++FP Q + + +S +R+A + DT+RH+ LP + + + +L S G L FE++ + Y P + IAKG LPL L +I V S + ++Q + + + V VL++ + Y+T Q+ AV +K + Q + + +I A+GL+ AA+ + P + YP+ GVN +V+ ++ + RI TKT+ R+F P++ D +L+ +D +++ +LAE + G + EV+H + I D V + IL+G + + LL R +G G W I P L W + E + + G +E+ L F +K DR ++ A G+ P +E D WQ D+H ITV ++++ L +A+ T ++ + RY + + S + +G + ++H+Q F + S L YLRE +LEIQAW + AR D +L+G DL +L L Q + +S + PL+K G NN ++ I VS++ + G+ ++ + + E+ +++ ++ + S + G+F ++ + SF V + VE+A++L P+ + +G P Y VS+ A K S + VW++ +TRL L E L KV++ SD+ + + ++VL G V +DL L KG ++ GWYNI+D G C+GQIKV +TP L NT S + S +S PTK LT D SS+ +L+ + + ++ +Q ID+ + +KS+L +LK +++ELD++ +
Sbjct: 119 KLEPMTLHTMLFIQEGRQISMIGVPPIHMAKKHPALMKPQPEGRDSSIRNTYLVCRMFW-CNDAVHSDVCWGTLN----------PEYNFLQVAPVLMTSQLMERLRNNFMIVEVWDKKVGSESDKLIGMVKLSLHQFFMSFRERKIANALLKSEYPVMAIDNYMPIVDPFSGLHFGQLKVVLAMGSEDQIATLQRLVIPNSVQSVPQRPSLYLERQDIMNGGDMVNV------SNKAVDHQFEITIEGIRDLKLFEN---MMWGETDCFVQFFFPAQGEGTGDGVLTLKSMPTMKCYRTATTLCTPDPTFHDTSRHKITLPFGTPVQRELLTACANSGGGVTGLPFEVWCRYYHPNVRDQLIAKGLLPLAKLCAMITMLKTGEPCVQSFSLRLSQAGQDGQPDKMEVAAKSKSVGVLDVTINYKTFAAQSDSSPAVDRKFKGS-----QVCLSVGVIRASGLKAAADYMALIDPSMAYPADVGVNSYVRIKMSFLGKENERI--------------TKTVARSFVPEYSHYMDFPCPLLMTNTLDTDST-----SLAELLETG--EALFEVWHQIPTGINRDYQSDKSTNGLRQLVYKTGDILLGTAIVPLVSLLTRRTGVNG--WFAINLP----------SLGWIKPVDEEGHPSTALDQVAGGLELSLRFANKEDRDRVVNAARSVGWS-PIDVDVEQTD--WQDEDSHH-NVHNITVGVDQVSF--PLASALLTGHSELDPTA-RCYIRYIFYDKGAVVSKCRKMTTSH-SGTLLSTLDHKQSFMFPHSAPLQWYLREERLEIQAWVTHDKGRAREKKPRQRD--------KLIGCCYLDLESLTDLRRGQ--QRISGLYPLFKPGCNNLKSAFIRVSITSRVSGSIKTISAEHKETNEDLDMSVSETDQSESGHDWMGDFTIDKSPKKNQSGSKDPAASFGVLLAVERAMHL--PMVTERNRSG---EVCPTTY-VSYQSAERSKPTCSPVFPNSSNPVWDYAVETRLSTEYLYKENKNLVLKVWHKPSDAAKSPDKSTDRVL-GFVSIDLSPLNKGLLQICGWYNIIDFNGQCRGQIKVSITPQDHAGSGLAHNTPSTSFILPS-FSLPTKSLTTGD---VASSIAHQLMSLQQQVMQRMTSLTAASGSTQAIDNAEAKDEELPCTHHWQPQFTSETRTNDSSKSYLESSLKRQLQELDSITQ 1241
BLAST of C2 domain-containing protein 3 vs. TrEMBL
Match: K1Q143 (C2 domain-containing protein 3 OS=Crassostrea gigas OX=29159 GN=CGI_10017125 PE=4 SV=1) HSP 1 Score: 310.071 bits (793), Expect = 9.823e-81 Identity = 279/1040 (26.83%), Postives = 464/1040 (44.62%), Query Frame = 1
Query: 2347 SCNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDLMMSKENTFNG--------HWNRNYLT-------NAFSSNELVEHSIEMDIESLGNFLVENYSELPLKESYFYIQYYFPLQNSISDNNGKNWESAV-----FRSANCQVERNVDISDTNRHRFRLPIDSSL-KAILNKHFESLGKKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLINQHSVDVDSLAETVTQQQLPVRLVNEDHGDSTYP--------VAVLNIRLCYRTSVVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGV--------FDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPI-FSPINSDAGLGGLKLNWPSKKNNES--LYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMF-KQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDVRLLGSALFDLSNLILPSDQLNKSVSHILPLWKRGLNNCGNSNITVSMSICGASSPLAGYNSDNEEESNL---NATKIPNNHSIQNGNGNFHRLR--ADHQ-----------SFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNYFVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTP 5295
S N YL+ R+ W + S + W D + F + ++++ LLE+++NNF ++E+WD T+ L G+VK+ ++ F+MSF++ KI +L + YP+++VD+++ I DP++G GQ+ VLLAMGS +Q+ L K + G H + N T N F ++ LVEH E+ IE + + + + E+ +IQY+FP Q+ +V FRSA + +D RHR LP S + + +L S + FE++ + Y P + IAK LPL L ++ + + +T T LP+ V D G P +L + + Y+T + N + + + Q + + ++ A GL+ AAESL T +QYP+ GVN ++K L+ + RI T+T+ R+F P+F + I + ++ L +LAE + G QL ++V+H V + D T +L+G + ++ +L +G G W PI SP N S+ N ++ + + VG VE+ + F +DR+ ++ + G+ P ++E E+ W D F +IT+ +++ L NA+ T +K + + RY+++ K ++ S + D G + + H+ S YLRE KLE+Q W Y N H + +L+G+A +L L + + VS + PL+K G N G I +++ P+ G E E+N+ + T N S +GN R + + H SF V + VE+A++L P +S +G L N +VS+ A + + VW+ + +TRL LL E L FKV++ S T + ++VL G V +DL L G +++ GWYNI+D G CQGQIKV + P
Sbjct: 1097 SRNTYLVCRMFW-CDDAVHSDVCWN----------DPQPPYNFSQIAPVLVSQSLLERMRNNFMVVEIWDKKTNAENDKLIGIVKLSLHQFYMSFRDRKISSALLKSQYPVIAVDNYLPIVDPLTGSQYGQLKVLLAMGSAEQVSALQRMKMESAAGLQVLRPSHHLDGNLETSQEGASRNQFGTSVLVEHIFEVVIEGIRGLSM--FDNMMWGEADCFIQYHFPTQSQTEVPGAPIVRHSVPKMKTFRSATTLCIPDPTFNDITRHRLCLPQGSPVQRELLTACAGSGSSGGVPFEVWCRYYHPNVRDQCIAKTSLPLAKLCAMVTMQKRN-EPAVQTFT---LPINSVTGD-GQEEDPEQKAKQKDCGLLTLTIHYKTHIAHNESSTEA-HRNIGQSQVCLTVGILKACGLKAAAESLAYTDSGMQYPAEVGVNTYIKVQLSFLDKSEERI--------------TRTVARSFAPEFSHTMDFPCNLIWTEADNEAL--SLAEILERG--QLQLQVWHQVPGLASDIDRQMMLEDTTRDKKLGDVLLGTCEVPLSTVLTHRTGISG--WFPITVSP------------NVSSEDNMDASGYHGNYLHRVVGGVELEVKFAHHNDREKVIHAGRNVGW-SPVDLQVEDEE-EWMSDDESSDRFYHITICVDQANF--PLANALATGHDTLEKGA-RCYVRYKLYDKAAVLSKVTKMADSD---GILTSELGHKHTLNIPASSPFRWYLREEKLEVQVWVSYS----YNQSQRPQHRD-----KLIGTAYINLETLA-DTRRTQHRVSGLYPLFKAGGANLGGGFIQAHVTL----KPMFGIPRQRENEANMSDIHDTDYDPNDSFHQLSGNTKRSKPISKHARVQEEDEEVVPSFSVLISVERAMHL--PRVSENSRSGEHLP----NTYVSYQTAESADPTFTDVFPNSDNPVWDHQNETRLSTELLYQENRNLVFKVWHKPSTCGKTPDKCSDRVL-GFVSVDLTPLASGLQQMCGWYNIMDFNGQCQGQIKVNIIP 2056
BLAST of C2 domain-containing protein 3 vs. TrEMBL
Match: V3ZEF6 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_165110 PE=4 SV=1) HSP 1 Score: 295.049 bits (754), Expect = 4.443e-76 Identity = 294/1078 (27.27%), Postives = 490/1078 (45.45%), Query Frame = 1
Query: 2338 DTKSCNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDLMMSK---ENTF----NGHWNRNYL--TNAFSSNEL----VEHSIEMDIESLGNF-LVENYSELPLKESYFYIQYYFPLQNSISDNNGKNWESAVFRSANCQVERNVD---ISDTNRHRFRL----PIDSS-LKAILNKHFESLGKKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLINQHSVDVDSLAETVTQQQLPVR----LVNEDHGDSTYPV--AVLNIRLCYRTSVVQNAVR-----QKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKF----DCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSI-----YSDITEVPPS-----SKILIGKGRISIADLLLRSSGFMGPIWLPIFSP-INSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDVRLLGSALFDLSNLILPSDQLNKS---VSHILPLWKRGLNNCGNSNITVSMSICGASSPLAGYNSD-NEEESNLNATKIPNNHSIQNGNGNFHRLRA-----------------DHQSFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNYFVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTPTIPLVPNTAVLS-KVSSSVYSPP 5361
D + N YL+ R+ W ++ S + WG+S+ N+ F++ +++T LLE+++NNF I+EVWD T L G++K+ ++ F MSF+ KI ++ + +P+++VD+++ I DP +G GQIHVLLAMGS +Q+ L + EN+ H R L A +L VEH E+ IE + N L EN + E+ ++QY+FP Q + +G + RS + +D NRHR L P+ L A N S G + FE++ + Y P + IAK LPL L ++ S+ QLP+ N D T + +L++ L Y+T +++N V +++NTS+ I + +I A GL+ AAE + ++YPS GVN +++ L+ +Q+ + + TKT+ RTF P+F D +L + D S AE + EV+H V S+ + + PS S L+G +S+ LL + +G G W PI P I + + + N+ +++E L + VG +E+ + F + DR ++ G+ P + LET D + N + I + I+ I L NAI T + +++ + RY+ + + S N + ++ A + +NH+ Q+ S YL+E +LE+Q W Y + R + D +L+GSA +L L + N+S +S + PL K G N S + + + I P N D ++EE +L + ++ Q+ +FH+L + SF VHV +E+A++L + + S SY VS+ +++ K + + I +W+ +TR+P + L + L KV++ SD+ + + ++VL G V +DL L G ++ GWYNI+D G CQGQ+KV +TP L P S +++SSV S P
Sbjct: 1043 DMTARNTYLVCRMFW-CNDAVSSNVCWGSSQ----------PNYNFLQIVPVLMTPSLLERMRNNFMIIEVWDKKTTAENDKLIGIIKLSLHQFFMSFRERKIANALIKSQFPVVAVDNFLPILDPFTGYQFGQIHVLLAMGSTEQVTVLQRQRIEGENSAPERPQHHLERQDLFSKEAIYKTDLQPNSVEHCFELSIEGIKNLKLFEN---MIWGEADCFVQYHFPTQ---LETDGVKHATPTLRSYRTGTTLCIPDPVFNDGNRHRITLDQGVPVQRELLTACANS---SGGSGGLPFEVWCRYYHPNVRDQVIAKATLPLAKLCAMVTMQKRGEPSIQTF----QLPLSHNTMTTNTDPELKTKCMDSGMLDVTLHYKTQLLKNDVNLNRPISRSINTSN----VCISVGVIKAAGLKTAAEHVARFDQSMEYPSEVGVNTYIRIKLS--------------FLQQGE-RLTKTVARTFAPEFSHYLDFPCPLLFTQPLADAQSLAEILESAEAVF--------EVWHQVPGSMGIANPSNQSDDYKPSTSNRTSDTLLGTVTLSLYSLLTKKTGING--WQPIIRPTIGWNQSVDQSEDNFLQSESSE-FTGLH--RVVGGLELSVRFANPEDRDHVISSGRSVGW-SPIDSNLETVDWDLDGVSNKD--YSKIKIGIDYICF--PLNNAIVTGQTVLDRNA-RCYVRYKFYDKRAVISKNVTMETND-ASYVVCSLNHKHQYILPKSSTYQWYLQEERLEVQVWVTYSRKDR------GEKRPKQRD-KLIGSAFIELEQL----SRHNRSQHRISGVYPLIKPGCNKMRGSCLQLQIGI----KPHHTQNGDSSDEEIDLLVSDTEQDYDSQD---SFHQLTSRTGTSPSKQHDRTAGLNTENSFMVHVSIERAMHLPTVSHKDRSEEVAPTSY------VSYQISDKSKPIHTDIFPSSTAPIWDHSRETRIPNTYLIQDNKNLVLKVWHKPSDAAKSPDKSSDRVL-GFVSVDLSPLSSGLLQICGWYNILDFNGQCQGQMKVNITPQTNLSPQRNTDSQQINSSVPSIP 2032 HSP 2 Score: 85.5001 bits (210), Expect = 1.716e-12 Identity = 62/241 (25.73%), Postives = 115/241 (47.72%), Query Frame = 1
Query: 34 NVVVNTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLEPTQLHKTLEKTYVKPIITNELN---EKAELRTSLNKSHESMKPK-----FIDESHEIEEKSENVLDRL-IETSKKIRETISIDVKDDEIND 729
+V V TSLPP ++ F + + I W + + + +V+ WWGED G+ F P V G + T A YP+R L FT+YL+DM L ++++ +G A I ++ L + K + L + N +D +I E+ + + +EP + I+ E++ E A L + H + PK F+ + + + S+ V + + + + +R+T++ D+ D ++ D
Sbjct: 25 DVKVFTSLPPQVDGQLRCF-CKVAVEEIIWSTDIPNPPVLTLVRTKWWGEDGEGSTFKPVDVLQQG-RTTFCTTARYPIRSGLKQFTSYLNDMGCLTLEVLSGPMAIAVGTAEITEISSLSNMKPISGLIPVFNPEDQQIAELKVSIVIEPLMASYDSMGSIPTTDISMEMHVTQESALPHRVLPEPHSHLPPKPDDDLFVSPASHLNDDSQRVENGISLRYADDLRQTLNYDLPDVKVKD 263
BLAST of C2 domain-containing protein 3 vs. TrEMBL
Match: A0A210QQZ6 (C2 domain-containing protein 3 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT12334 PE=4 SV=1) HSP 1 Score: 291.967 bits (746), Expect = 3.330e-75 Identity = 292/1126 (25.93%), Postives = 503/1126 (44.67%), Query Frame = 1
Query: 2263 SLQSLLYVSSIRY--VNPKS----TVNGYKS-DTKSCNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDLM-------MSKENTFNGHW-------NRNYLTNAFS---SNELVEHSIEMDIESLGNFLVENYSELPLKESYFYIQYYFPLQNSISDNNGKNWES------AVFRSANCQVERNVDISDTNRHRFRL----PIDSSLKAILNKHFESLGKKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLINQH---SVDVDSLAETVTQQQLPVRLVNEDHGDSTYPVAVLNIRLCYRTSVVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITE---------------VPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESL-----YALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGC-TFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSPNF-CINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDVRLLGSALFDLSNLILPSDQLNKS--VSHILPLWKRGLNNCGNSNITVSMSICGASSPLAGY---NSDNEEESNLNATKIPNNHSIQNGNGNFHRLRADHQS--------------------FPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNYFVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTPTIPLVPNTAVLSK--VSSSVYSPPTK-PLTV 5379
SLQ + +SSI+ V P + G KS D + N YL+ R+ W ++ S + WG + F F + ++L+ LLE+++NNF ++EVWD T L G+VK+ ++ F+MSF++ KI +L + YP++SVD+++ I DP+SG GQ+ VLLAMGS +Q+ +L M + H+ + L +S ++ VEH E+ IE + + + + E+ +IQY+FP+Q SD G + FRSA + +D RHR L P+ L + G + FE++ + Y P + IAK LPL L ++ V S A + Q + + ++++ + Y+T +Q+ Q N + Q I + +I A+GL+ AAE++ +QYP+ GVN ++K ++ + RI T+TI RTF P+F + P++ E N LA + +L +E++H V + SD+ V + +L+G +S+A LL +G G W + P L G + + ++ E LE + VG VE+ + F +DR ++ A G+ + + ED WQ D+ GC + ITV ++++ + NA+ + K++ + RY+++ +S S + C D G I +H+ +F IS YLRE KLE+Q W YG + + + + H + +L+G+ +L L +D+ + +S + PL+K G + G + + ++ + P G SD+E + ++ ++ + + N +FH++ +S FPV V VE+A++L PL + + + Y P N +VS+ + + + VW+ + +TRL LL E L FKV++ + + ++VL G V +DL L G ++ GWYN++D G C+GQIKV + P + + +S V+ S Y+ P+ P T+
Sbjct: 894 SLQGIPSLSSIKRHPVFPPQPHTLSSEGMKSRDMNTRNTYLVCRMFW-CNDAVHSNVCWGTFE----------PQFNFGQIAPVLLSGSLLERMRNNFMVVEVWDKKTSAENDQLIGIVKLSLHQFYMSFRDNKISNALLKSQYPVISVDNYLPIVDPMSGSQFGQLKVLLAMGSGEQVTELQQLKLDGPMVRPPERPQHFLEREDMMRQGSLAPVYSQPRADNSVEHIFEVVIEGIRGLAL--FDNMIWGEADCFIQYHFPVQPP-SDQPGTGPANDGIPSMKSFRSATTLCIPDPTFNDITRHRIVLSQGTPVQRQL--LTACAGAGGGSGGVPFEVWCRYYHPNIRDQCIAKASLPLAKLCAMVTMQKRGESSVQSFALPLKQVAVDTEFSDARAKSQVKESGLMDVTIHYKTQNIQSEQNQAA-NKNLSGAQICISVGVIRASGLKAAAEAIARLDSGMQYPAEVGVNTYIKIRMSFLPTEDERI--------------TRTIARTFAPEFSHHMDFPC-PLLWTEADN---DALALAEILETAELTLEMWHQV-PGLSSDLDRQIAQQTTHEVQGRRLVEKTQDVLLGTATLSLAGLLTNRTGING--WFAVNLP------LIGWRQDASQAEDEEDRTVPCNQGLE--RVVGGVELSVKFAHHNDRDRVVHAARGVGWSPVDLDVEDEED--WQS-DDEGCGQYHQITVCMDQVSF--PIQNALIAGQTNLDKTA-RCYIRYKVYDRSAVVSRSVKCRILD--TGYILSHCDHKHEFQIPISSPFKWYLREEKLEVQVWVSYG---KKDGNQKSQHRD-----KLIGTTYIELDAL---NDERRRQHRISGMFPLYKPGAASLGGAFLRAHIT----AKPQFGSVTKQSDDEADEKVSEGEVDEEY---DPNDSFHQIMGKKKSKSSTDVPHLERVEEDSVVPHFPVIVSVERAMHL--PLISDKNRSE---EYFP-NTYVSYQTSESASPAYTQVFYNSDNPVWDDQQETRLSTELLYQENKNLVFKVWHKPQSASKDPDKSSDRVL-GFVSVDLTPLTSGLLQICGWYNVMDFHGQCRGQIKVNIVPQDDVTRHVQGISGQPVAMSFYNQPSSLPFTI 1940 HSP 2 Score: 82.8037 bits (203), Expect = 1.348e-11 Identity = 62/195 (31.79%), Postives = 92/195 (47.18%), Query Frame = 1
Query: 34 NVVVNTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDII-VKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLE------------PT-----QLHKTLEKTY---VKPIITNELNEK 555
+V V+T LPP ++ F L I+ I W S N D+ V+V WWGED +G +F P V G K K A YPVR F +YL DM L V+I+ +G+A I ++ L + + + L +L+ ++ K+ EI + LE PT + H T E Y V+PI ++ +K
Sbjct: 22 DVQVHTGLPPQVDGQLRCF-CRLTIDQIHWHSP---NPPDVAHVRVKWWGEDGDGGLFRPLNVK-KGDKGPAKVTARYPVRSGPRQFASYLVDMGSLVVEILSGPTMIPVGQAEITQIGLLSNVRPIDGLYPVLSPREEKLAEIHASLVLESLMASYDSTGSIPTTDISMETHATQESMYPQRVQPIPHSQAPQK 211
BLAST of C2 domain-containing protein 3 vs. Ensembl Cavefish
Match: c2cd3 (C2 domain containing 3 centriole elongation regulator [Source:NCBI gene;Acc:103046868]) HSP 1 Score: 213.386 bits (542), Expect = 1.073e-54 Identity = 263/1074 (24.49%), Postives = 440/1074 (40.97%), Query Frame = 1
Query: 2353 NLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDL--MMSKENTFNGHWNR-----------NYLTNAFSSNELVEHSIEMDIESLGNFLVENYSELPLK-----ESYFYIQYYFPLQ--NSISDNNGKNWESAV----FRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFESLGKKH---ILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLINQHSVDVDSLAETVTQQ-QLPVRLVNEDHGD-STYPVAVLNIRLCYRTSVVQ------NAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIID-DENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGY-----------VVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSS----PNFCINEDEIAGK---------IFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDV-RLLGSALFDLSNLILPSDQLNKSVSHILPLWKRGLNNCGNSNITVSMSICGASSPLAGYNSDNEEE-----SNLNATKIPNNHSIQNGNGNFHRLR------------------------ADHQSFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNY---FVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTP 5295
N+YL +L + + E +S + WG + F V+ + L S LLE++KNN I+EVW + L GLVK+P++ F+MSF++ KI + +L + YP+L+VD ++ + D +G ++G++ V LAMG QQI L M +E R NA + L EH + +E + PL+ E+ YI Y FP Q ++ D + ES+V +R+ ++ + H ++ +L S G I FE++ + Y P + +A+G LP+ L ++ + +T Q LP+ + D P +L + + YRT V+ A+ + +N ++++ + A + LQY S GVN V L+ S ++SR ST+ + R+F+P+F+ +E ++ D + L E + N + GV S D ++G RI +ADLL + +G G W GL L PS ++ +L +VG +E+ + F +DR+ +L A G+ L +E WQ + ++V + L + + P + S RY+++ Q S P E+E +G+ + P N + R S L YLRE +LE+Q W +G R P+D RL+GSA DLS L + S Q ++S + PL+KR + G + + ++ S+ L EEE ++P + ++ +G R ++ ++F + VE+A++L S+ G L+ + + VS+ A+ +++ +++ VW+ + RL LL + + L FKV++ GE+ E+V IG +DL LL GF+ V GWYNI D G CQGQIKV V+P
Sbjct: 692 NVYLNCKL-FGSEETTRSVVSWGQTH----------PTFNLVQVAPVALNSRLLERMKNNVMIIEVWLRAGSSHNDKLLGLVKLPLHQFYMSFRDPKISQLLLKSQYPVLAVDSYMPVVDIFTGGTRGRLRVCLAMGLSQQITSLQRMRDEELASVSQIPRPAHLLDHRPVPEIKANAAPATALNEHVFVVRVEKVRGLT-------PLQSTVWGEADCYIHYSFPAQEDDARQDVDPHVVESSVNLKSYRTVTTLCVPDLVFGHSETHVLVASPAVPVQRLLLSSLASQGPSAVGGIPFEVWCRYYYPNVREQLVARGVLPMAKLCAMVT-----MQRQGQTEAQLFSLPLIPRTDRPSDVQPQPSGLLEVSVQYRTRPVRGTGVSSGALASRMVNL-------VVQVHRAAGLQAAARAAA-------LQYYSEVGVNCFVTIQLSLLSERESR--------------STRVVARSFSPEFEYHAEFCCQMLVQRDTGESVSLVELLEDAVAVFTVYNRDTRKGVGASTPKD---------AVLGSVRIRLADLLHKRTGISG--WY-------------GLSLP-PSASSHCNL------TTVGGLELSIHFSHHADRERVLSSARLLGWQDKGDDGEEKEEDKEEGDLGSER--WQSLG--------LSVSMPRAWLP---THCLLLPGHTELQRSTYCYYRYKLYDQDTFCSQLRHPILEAIEEEESGRADLDSGIATVAFPGNQTAEL--RGSQPLLWYLREERLEVQLWVSFGKGKRT----------RPHDSDRLVGSAFLDLSTLTIASKQ-KLTISGVYPLFKRSAADLGGAALRAHITATTGSACLPAPALPEEEEQVSSPGEEEEDQVPLSRLSRSADGVSRWCRVPSRQPTKSTIISEPQPPSRGAELSEEETFTARISVERAMHL--------SLKGCPLAERSGSLPSCCVSYAVADSSATLSTDVVQDSDCPVWDHHQECRLSKELLVDPQQALVFKVWHK-------GEL--ERV-IGFASVDLSPLLSGFQSVSGWYNITDFSGQCQGQIKVSVSP 1639
BLAST of C2 domain-containing protein 3 vs. Ensembl Cavefish
Match: c2cd3 (C2 domain containing 3 centriole elongation regulator [Source:NCBI gene;Acc:103046868]) HSP 1 Score: 213.001 bits (541), Expect = 1.163e-54 Identity = 263/1074 (24.49%), Postives = 440/1074 (40.97%), Query Frame = 1
Query: 2353 NLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDL--MMSKENTFNGHWNR-----------NYLTNAFSSNELVEHSIEMDIESLGNFLVENYSELPLK-----ESYFYIQYYFPLQ--NSISDNNGKNWESAV----FRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFESLGKKH---ILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLINQHSVDVDSLAETVTQQ-QLPVRLVNEDHGD-STYPVAVLNIRLCYRTSVVQ------NAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIID-DENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGY-----------VVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSS----PNFCINEDEIAGK---------IFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDV-RLLGSALFDLSNLILPSDQLNKSVSHILPLWKRGLNNCGNSNITVSMSICGASSPLAGYNSDNEEE-----SNLNATKIPNNHSIQNGNGNFHRLR------------------------ADHQSFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNY---FVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTP 5295
N+YL +L + + E +S + WG + F V+ + L S LLE++KNN I+EVW + L GLVK+P++ F+MSF++ KI + +L + YP+L+VD ++ + D +G ++G++ V LAMG QQI L M +E R NA + L EH + +E + PL+ E+ YI Y FP Q ++ D + ES+V +R+ ++ + H ++ +L S G I FE++ + Y P + +A+G LP+ L ++ + +T Q LP+ + D P +L + + YRT V+ A+ + +N ++++ + A + LQY S GVN V L+ S ++SR ST+ + R+F+P+F+ +E ++ D + L E + N + GV S D ++G RI +ADLL + +G G W GL L PS ++ +L +VG +E+ + F +DR+ +L A G+ L +E WQ + ++V + L + + P + S RY+++ Q S P E+E +G+ + P N + R S L YLRE +LE+Q W +G R P+D RL+GSA DLS L + S Q ++S + PL+KR + G + + ++ S+ L EEE ++P + ++ +G R ++ ++F + VE+A++L S+ G L+ + + VS+ A+ +++ +++ VW+ + RL LL + + L FKV++ GE+ E+V IG +DL LL GF+ V GWYNI D G CQGQIKV V+P
Sbjct: 775 NVYLNCKL-FGSEETTRSVVSWGQTH----------PTFNLVQVAPVALNSRLLERMKNNVMIIEVWLRAGSSHNDKLLGLVKLPLHQFYMSFRDPKISQLLLKSQYPVLAVDSYMPVVDIFTGGTRGRLRVCLAMGLSQQITSLQRMRDEELASVSQIPRPAHLLDHRPVPEIKANAAPATALNEHVFVVRVEKVRGLT-------PLQSTVWGEADCYIHYSFPAQEDDARQDVDPHVVESSVNLKSYRTVTTLCVPDLVFGHSETHVLVASPAVPVQRLLLSSLASQGPSAVGGIPFEVWCRYYYPNVREQLVARGVLPMAKLCAMVT-----MQRQGQTEAQLFSLPLIPRTDRPSDVQPQPSGLLEVSVQYRTRPVRGTGVSSGALASRMVNL-------VVQVHRAAGLQAAARAAA-------LQYYSEVGVNCFVTIQLSLLSERESR--------------STRVVARSFSPEFEYHAEFCCQMLVQRDTGESVSLVELLEDAVAVFTVYNRDTRKGVGASTPKD---------AVLGSVRIRLADLLHKRTGISG--WY-------------GLSLP-PSASSHCNL------TTVGGLELSIHFSHHADRERVLSSARLLGWQDKGDDGEEKEEDKEEGDLGSER--WQSLG--------LSVSMPRAWLP---THCLLLPGHTELQRSTYCYYRYKLYDQDTFCSQLRHPILEAIEEEESGRADLDSGIATVAFPGNQTAEL--RGSQPLLWYLREERLEVQLWVSFGKGKRT----------RPHDSDRLVGSAFLDLSTLTIASKQ-KLTISGVYPLFKRSAADLGGAALRAHITATTGSACLPAPALPEEEEQVSSPGEEEEDQVPLSRLSRSADGVSRWCRVPSRQPTKSTIISEPQPPSRGAELSEEETFTARISVERAMHL--------SLKGCPLAERSGSLPSCCVSYAVADSSATLSTDVVQDSDCPVWDHHQECRLSKELLVDPQQALVFKVWHK-------GEL--ERV-IGFASVDLSPLLSGFQSVSGWYNITDFSGQCQGQIKVSVSP 1722 HSP 2 Score: 77.0258 bits (188), Expect = 2.798e-13 Identity = 43/151 (28.48%), Postives = 83/151 (54.97%), Query Frame = 1
Query: 34 NVVVNTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLEP 486
+V +TS+PP + + + +L + ++ + W ++ +V++ WWGE S G +F PR +L +++VK+ +PVR FT+YL+DM L +D++ K H I R I + +L + ++ +++ K+GE+ + + LEP
Sbjct: 18 DVSPSTSVPPLV-EGQVRCFLRVTVSRVLW--TINRPPPVTLVRLRWWGESSGGTVFCPRDGSLT-RQKDVKSTCRFPVRCGPKQFTSYLTDMGSLVLDVLTKPDHLPIARVQIAGIARLSLSHSINGFFTLVSPTSEKLGELQVALALEP 164
BLAST of C2 domain-containing protein 3 vs. Ensembl Sea Lamprey
Match: c2cd3 (C2 domain containing 3 centriole elongation regulator [Source:ZFIN;Acc:ZDB-GENE-060503-104]) HSP 1 Score: 213.001 bits (541), Expect = 1.836e-55 Identity = 227/990 (22.93%), Postives = 420/990 (42.42%), Query Frame = 1
Query: 2296 RYVNPKSTVNGYKSDTKSCNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDLMMSKEN------TFNGHWNRNYLTNAFSSNELV------------EHSIEMDIESLGNFLVENYSELPLK-----ESYFYIQYYFPLQNSISDNNGKNWES-----AVFRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFESLGKKH---------ILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLIN-QHSVDVDSLAETVTQQQLPVRLVNEDHGDSTYPVA-VLNIRLCYRTSVVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMF-KQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDV-RLLGSALFDLSNLILPSDQLNK----SVSHILPLWKRGLNNCGNSNITVSMS-------ICGASSPLAGYNSDNEEESNLNATKIPNNHSIQNGN--GNFHRLRADHQ----------SFPVHVIVEKAVNLKSPLFGNDSITGTELSYK---PLNYFVSFPCANEDKCVTSSIIKGCKEAVWNFECDTR 5064
R +P S ++G + + + YL+ +L +++ E +S + W ++ F + + + + +T +LLE++ NN ++EVW+ L GL K+P++ FHMSF + + +L YP+++VD ++ + D SG G++ LLAMGS Q+ L K TF+ + A S+ V EH E+ + S+ + PL+ E+ Y+QY+FP Q + +D N++ +R+A + DT H + S + + E+ ++ I FE++ + Y P + +A+G LPL L ++ Q D + A + LP++ +P A +L + + Y+ + + + +SP+ + + + A GLQ AA P + YP+ GVN V L+ V + G + T+ + R+F+P+F+ +EV + ++LAE LC + + V+ ++ S ++ + ++G R+ +A LL R+SG G W P+ S AG+G P N + VG +E+ + F DR+ +LQ A G+ + E +D + + + V + + L E+ + P + I RYR++ +++ S P G + ++H + F ++ L Y+RE +LE+Q W A + + P+D RL+GSA DLS+L+ P Q + +VS + PL+K G ++ + + V ++ + G ++P A SD E + + ++ ++ + RLR D++ +FP V+VE+A++L S G+ S + PL++ VS+ + + V + + VW TR
Sbjct: 802 RLYSPSSRLSGGSAQQEPSSAYLVCKL-FSSKEVTRSAVCWSSAT----------PLFNYSQVSPVQVTPQLLERMNNNVMVIEVWNKEAGPGPDQLIGLAKLPLHHFHMSFSCTYVSRLLLEAQYPVVAVDGYMPVVDVFSGSCVGELRALLAMGSSNQVLALQRLKGEEVTSVPTFHSAARSMGESAAQPSSSQVPLQEPEQYGLREEHVFEVHVGSVRGLV-------PLQSGVWGEADCYVQYHFPAQPN-ADEPVINYDELSLSMCAYRTATTLCVPDPVFRDTQTHAL---VASPGEPVQRLLLEACSRQGGPDSPGGGGIHFEVWCRYYYPNVREQLVARGTLPLAKLCAMVTLQRRGDAGAQAFS-----LPLKAQTAPGHHPPHPSAGLLELSVAYKHRPITGSTHAEP--GASPHLV-TLALTVHRAMGLQAAARLAAERDPSMHYPAEAGVNACVSLGLS--------FAVAAAGRENV----TRAVARSFSPEFEHGAEVAC--HVVSRGMAGESRSLAE-TLCSAHAIFTVVHQSIYSRGRS--SDAARARGAVLGVTRVPLAALLSRTSGIHG--WFPV-----SPAGVGHGGREAPDPLN----------QCVGGLELSVAFAHAGDREKVLQAARYLGWKHHCLEQEEKDDAMSEEAFIEATV--ALKVAVPKAWLPERCLPDFNAPSRPAPE-DIHCYLRYRLYDAEAVCSRPRRPQRSCGDDGGAALDLHHARTFRLPLARPLRWYMREERLELQLW------ASGAGQKIGSRSRRPHDTDRLIGSAFVDLSSLVPPRPQRHTQDKCTVSGVYPLFKYGADDLAGAALRVHVTRSLDGRHVSGDATPHAALPSDGEATDDDEEEDDDDGYNDRDATNESGWTRLRVDNELDGEGRSRGANFPALVVVERAMHL--------SCVGSPRSRQGAPPLSFRVSYAVCGDAEPVFTEAVGTSSSPVWEHHLQTR 1710 HSP 2 Score: 79.337 bits (194), Expect = 1.112e-14 Identity = 47/150 (31.33%), Postives = 84/150 (56.00%), Query Frame = 1
Query: 49 TSLPPSINKSEPFFYLNLHINYIKWIS-----KVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLE 483
TSLPP + + +P +L + + + W + +VS+ + + V++ WWGE S G IF P +LAG ++ ++ A + V F++YLSDM L ++++ K +H +GR I+ + +L + + IL+ K+GE+ + MTLE
Sbjct: 7 TSLPPLV-EGQPRCFLRIRVGALVWSAGGAGPRVSTVHAPL-VRLRWWGEGSGGTIFRP---HLAGGTRSPQSFARFSVCCGPKQFSSYLSDMGTLVLEVLAKLEHLPVGRVHINHISRLSATQPISGSFPILSSTSHKLGELQVSMTLE 151
BLAST of C2 domain-containing protein 3 vs. Ensembl Sea Lamprey
Match: c2cd3 (C2 domain containing 3 centriole elongation regulator [Source:ZFIN;Acc:ZDB-GENE-060503-104]) HSP 1 Score: 202.601 bits (514), Expect = 3.138e-52 Identity = 225/1004 (22.41%), Postives = 407/1004 (40.54%), Query Frame = 1
Query: 2296 RYVNPKSTVNGYKSDTKSCNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDLMMSKEN------TFNGHWNRNYLTNAFSSNELV------------EHSIEMDIESLGNFLVENYSELPLK-----ESYFYIQYYFPLQNSISD---------NNGKNWESAVFRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFESLGKKH---------ILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLIN-QHSVDVDSLAETVTQQQLPVRLVNEDHGDSTYPVA-VLNIRLCYRTSVVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMF-KQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDV-RLLGSALFDLSNLILPSDQLNK----SVSHILPLWKRGLNNCGNSNITVSMSICGASSPLAGYNSDNEEESNLNATKIPNNHSIQNGNGNFHRLRADHQ-----------------------------SFPVHVIVEKAVNLKSPLFGNDSITGTELSYK---PLNYFVSFPCANEDKCVTSSIIKGCKEAVWNFECDTR 5064
R +P S ++G + + + YL+ +L +++ E +S + W ++ F + + + + +T +LLE++ NN ++EVW+ L GL K+P++ FHMSF + + +L YP+++VD ++ + D SG G++ LLAMGS Q+ L K TF+ + A S+ V EH E+ + S+ + PL+ E+ Y+QY+FP Q + + +R+A + DT H + S + + E+ ++ I FE++ + Y P + +A+G LPL L ++ Q D + A + LP++ +P A +L + + Y+ + + + +SP+ + + + A GLQ AA P + YP+ GVN V L+ V + G + T+ + R+F+P+F+ +EV + ++LAE LC + + V+ ++ S ++ + ++G R+ +A LL R+SG G W P+ S AG+G P N + VG +E+ + F DR+ +LQ A G+ + E +D V T + V + + L E+ + P + I RYR++ +++ S P G + ++H + F ++ L Y+RE +LE+Q W A + + P+D RL+GSA DLS+L+ P Q + +VS + PL+K G ++ + + V ++ L G + ++ N + RLR D++ SFP V+VE+A++L S G+ S + PL++ VS+ + + V + + VW TR
Sbjct: 786 RLYSPSSRLSGGSAQQEPSSAYLVCKL-FSSKEVTRSAVCWSSAT----------PLFNYSQVSPVQVTPQLLERMNNNVMVIEVWNKEAGPGPDQLIGLAKLPLHHFHMSFSCTYVSRLLLEAQYPVVAVDGYMPVVDVFSGSCVGELRALLAMGSSNQVLALQRLKGEEVTSVPTFHSAARSMGESAAQPSSSQVPLQEPEQYGLREEHVFEVHVGSVRGLV-------PLQSGVWGEADCYVQYHFPAQPNADEPVPFPPAPLRRRTGLSMCAYRTATTLCVPDPVFRDTQTHAL---VASPGEPVQRLLLEACSRQGGPDSPGGGGIHFEVWCRYYYPNVREQLVARGTLPLAKLCAMVTLQRRGDAGAQAFS-----LPLKAQTAPGHHPPHPSAGLLELSVAYKHRPITGSTHAEP--GASPHLV-TLALTVHRAMGLQAAARLAAERDPSMHYPAEAGVNACVSLGLS--------FAVAAAGRENV----TRAVARSFSPEFEHGAEVAC--HVVSRGMAGESRSLAE-TLCSAHAIFTVVHQSIYSRGRS--SDAARARGAVLGVTRVPLAALLSRTSGIHG--WFPV-----SPAGVGHGGREAPDPLN----------QCVGGLELSVAFAHAGDREKVLQAARYLGWKHHCLEQEEKDDAV---------TTVALKVAVPKAWLPERCLPDFNAPSRPAPED-IHCYLRYRLYDAEAVCSRPRRPQRSCGDDGGAALDLHHARTFRLPLARPLRWYMREERLELQLW------ASGAGQKIGSRSRRPHDTDRLIGSAFVDLSSLVPPRPQRHTQDKCTVSGVYPLFKYGADDLAGAALRVHVTRS-----LDGRHVSATDDDEEEDDDDGYNDRDATNESGWTRLRVDNELDGEGRSRGAKRDIGKCGTTAPSEDKAADSFPALVVVERAMHL--------SCVGSPRSRQGAPPLSFRVSYAVCGDAEPVFTEAVGTSSSPVWEHHLQTR 1697 HSP 2 Score: 79.337 bits (194), Expect = 1.110e-14 Identity = 47/150 (31.33%), Postives = 84/150 (56.00%), Query Frame = 1
Query: 49 TSLPPSINKSEPFFYLNLHINYIKWIS-----KVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLE 483
TSLPP + + +P +L + + + W + +VS+ + + V++ WWGE S G IF P +LAG ++ ++ A + V F++YLSDM L ++++ K +H +GR I+ + +L + + IL+ K+GE+ + MTLE
Sbjct: 7 TSLPPLV-EGQPRCFLRIRVGALVWSAGGAGPRVSTVHAPL-VRLRWWGEGSGGTIFRP---HLAGGTRSPQSFARFSVCCGPKQFSSYLSDMGTLVLEVLAKLEHLPVGRVHINHISRLSATQPISGSFPILSSTSHKLGELQVSMTLE 151
BLAST of C2 domain-containing protein 3 vs. Ensembl Nematostella
Match: EDO47137 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNG2]) HSP 1 Score: 106.301 bits (264), Expect = 3.453e-23 Identity = 135/558 (24.19%), Postives = 223/558 (39.96%), Query Frame = 1
Query: 3874 ILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIE--EIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAW-------------GIYGS----EARCNNDYL----NDHNEN---PNDVRLLGSALFDLSN--------LILPSDQ-----------LNKSVSHILPLWKRGLNNCGNSNITVSMSICGASSPLAGYNSDNEEESNLNATKIPNNHSIQNGNGNFHRLRADHQSFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNYFVSFPCANEDKC-VTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDS---TGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTPTIPLVPNTAVLSKVSSSVYSPPTKPLTVEDHQSYL 5400
+L+G I + DLL +G G W +F P + + G N+ + K +G +++ + F + + +T++ +A G+ P TED +W++ D + + I +SE + + F G ++ + R++ + +S S + + + + V H + F S L YL E LE+Q W + GS + C + Y+ N +N D L S DLSN L P D+ +++S S P ++G N S+ SM G KIP+ N D +F HVIV++A +L PL + +G + P N +VS+ A D C V + ++ +W ++ R+ S L ++ L FKV++ S + E +G V +DL L G +IGWYN++ G+C+GQ+KVGV P P+ P + LS S V+SPP T S+L
Sbjct: 16 VLLGYVTIPLVDLLTHKTGIRG--WHALFPPKHLEPGT--------DLHGNDHVTT----KPIGGIQLSIKFSESNILETVVDVARSMGWCPP-PGVEATEDGLWENGDEDPSAHGGVELRIRTSRAWVSESIADD-FRSHAG--RNEVLGYVRFKFYDKSPICSRLVPLKKTKSC--FSLEVKHRKSFPLPASSSLAWYLSEEVLEMQVWLGGREDKLRKVLSALKGSWDYIDPLCLSSYVRSEENKREKNLCRNRDFCLFKSGSADLSNCGVHVQVSLTKPGDKASQQQEEQTQDMDESASTGYPSTEQGHGNGEESSSRSSMDRWG------------------TPQKIPSTPPRTNSE--------DKDTFAAHVIVQEARHL--PLV--PAASGERI---PPNVYVSYQ-ATADSCPVCTPVVATATSPLWEYQKLERIKLSTLKSQSLI--FKVWHRADISRPGPPSAEGAQGDRALGFVSMDLAPLAAGLRELIGWYNVMSFAGECKGQMKVGVIPLTPVSP-SRCLSTKSRLVFSPPQTSSTQAPSSSFL 516
BLAST of C2 domain-containing protein 3 vs. Ensembl Nematostella
Match: EDO47138 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNG4]) HSP 1 Score: 73.9442 bits (180), Expect = 6.527e-13 Identity = 79/299 (26.42%), Postives = 125/299 (41.81%), Query Frame = 1
Query: 2857 NELVEHSIEMDIESLGNFLVENYSELPLKESYFYIQYYFPLQNSISDNNGKNWES-AVFRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFES--------LGKKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLINQHSVDVDSLAETVTQQQLPVRLVNEDHGDSTYPV----AVLNIRLCYRTSVVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEV 3714
+ LVEH E+ +E + V + E+ ++QY+FP Q +D + S RS + D RH F LP ++ L F G I FEL+ + Y P + +AKG LP+ L ++ +V LP+ ++ D S + +LNI + YR S + K L T+ P DQ + ++I A GL+ AA T+ + YP+ G+N +V L ++SR +T+T+ R+F P+FD EV
Sbjct: 603 SSLVEHQFEVVVEDIRGLSV--FRSTVWGETDCFVQYHFPHQTPTNDALEEVTPSLKAHRSTTTLCVPDPSFQDVARHTFLLPGGLPVQKYLLAAFSGSWTGVGSLPGMSGIPFELWRRYYYPNIRDQLVAKGSLPVAKLCAMVTMQK----QREPSVQAFSLPLVVIPGDEDGSRQAMVQDTGLLNITVKYRHSTLST----KGL-TARP-DQVCLNFDVIRACGLKAAASYQARTNSSMAYPADVGINGYVVVRL--PFPRKSRF-------------TTRTVARSFAPEFDHHVEV 874 HSP 2 Score: 59.3066 bits (142), Expect = 1.839e-8 Identity = 33/103 (32.04%), Postives = 56/103 (54.37%), Query Frame = 1
Query: 2359 YLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNN 2667
YL+ R+ W + KS + W S F F + ++LT LL++ NNF ++EVW+ +T Q L G++K+ V+ ++SF++ KI KT+L +
Sbjct: 328 YLVCRMFW-CDDVTKSAVTWTTSN----------PRFGFKQVAPVLLTPTLLQRACNNFIVVEVWNKRVPQTDQ-LIGIIKVSVHQLYLSFRDPKITKTLLKS 418
BLAST of C2 domain-containing protein 3 vs. Ensembl Nematostella
Match: EDO28426 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6H9]) HSP 1 Score: 61.2326 bits (147), Expect = 1.341e-9 Identity = 38/156 (24.36%), Postives = 77/156 (49.36%), Query Frame = 1
Query: 22 NQNINVVVNTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGIL--NEKDTKIGEIMIVMTLE 483
++ I+VV SLPP+++ F L + ++ + W V +D+ ++V WWGE + A+ P AG + T YP+ F+ YL DM L +D++ ++G+A++ + L + ++ ++ ++ +K+ EI + + E
Sbjct: 25 DEQISVV--NSLPPAVDGQLRCF-LRVSVSKVTWT--VRHPPDDVGIRVKWWGEQGDSALLRP-VKKKAGVVKTDWTSVRYPICSGPKQFSAYLKDMGTLVLDMVHGPAKLLLGQASVPNIADLSASHPIKGFFSVMSVSQPSSKVAEIYVCVKFE 174
BLAST of C2 domain-containing protein 3 vs. Ensembl Nematostella
Match: EDO47139 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNG7]) HSP 1 Score: 58.5362 bits (140), Expect = 5.116e-9 Identity = 38/156 (24.36%), Postives = 76/156 (48.72%), Query Frame = 1
Query: 22 NQNINVVVNTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGIL--NEKDTKIGEIMIVMTLE 483
++ I+VV SLPP++ F L + ++ + W V +D+ ++V WWGE + A+ P AG + T YP+ F+ YL DM L +D++ ++G+A++ + L + ++ ++ ++ +K+ EI + + E
Sbjct: 25 DEQISVV--NSLPPAVYGQLRCF-LRVSVSKVTWT--VRHPPDDVGIRVKWWGEQGDSALLRP-VKKKAGVVKTDWTSVRYPICSGPKQFSAYLKDMGTLVLDMVHGPAKLLLGQASVPNIADLSASHPIKGFFPVMSVSQPSSKVAEIYVSVKFE 174
BLAST of C2 domain-containing protein 3 vs. Ensembl Medaka
Match: ENSORLT00000036926.1 (pep primary_assembly:ASM223467v1:13:9943706:9949932:1 gene:ENSORLG00000022243.1 transcript:ENSORLT00000036926.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 81.6481 bits (200), Expect = 4.833e-16 Identity = 43/145 (29.66%), Postives = 79/145 (54.48%), Query Frame = 1
Query: 34 NVVVNTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMI 468
+V +TSLPP + + + +L + I+ I W V + +++ WWGE S+G F+PR + K N+KT A +PVR T+YL+DM L ++++ KS H + RA + + +L ++ + +++ K+GE+ +
Sbjct: 21 DVSPSTSLPPLV-EGQLRCFLCVTISQIIWT--VQKAFSPTFIRLRWWGESSDGTHFIPRDGSQLSQK-NIKTTARFPVRCGPKQLTSYLTDMGALMLEVLTKSDHLPVARAQVAGISRLSLSQPISGFYPLVSPTSEKLGELQV 161
BLAST of C2 domain-containing protein 3 vs. Planmine SMEST
Match: SMESG000025571.1 (SMESG000025571.1) HSP 1 Score: 4115.07 bits (10671), Expect = 0.000e+0 Identity = 2143/2151 (99.63%), Postives = 2146/2151 (99.77%), Query Frame = 1
Query: 19 MNQNINVVVNTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLEPTQLHKTLEKTYVKPIITNELNEKAELRTSLNKSHESMKPKFIDESHEIEEKSENVLDRLIETSKKIRETISIDVKDDEINDAILRKRFPDIDQATDRKWIKEILVNESVNDDFSINDPSKLHTESILKTSGDFYPSKSVRRNNHTNSDRDLIKLITVSDSFCSASVTDFPDSKYQFLNHSEAXXXXXXXXXXXXXXXPCKRDSIIEELFYKQPESSSAPIMGIEAFKNKFINNECVPDLXXXXXXXXXXXDFEIYKCLSRNDYENNPNEKDMXXXXXXXXXXXXTKHEHVEMLPNGAADRNWYNNISSVKIFLDMLWLNSTPQRCNARSRSQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVTKPPTPQMFQLNPSHKYFIEYKFPTNALYTADKDKENLSNSMSTTRVLVKQTGFKCNISDSNGIKSLSLDHVSEFPVTFTNSAIIQKWWRGIVRFKLICQDSNKKETVVGVGVVPLRNIISTNNFYRLIPIRLPRNKSAKSNTRMVIGSXXXXXXXXXXXXKGFNSSDKKPEILFQDSSDSRNQISYYHPKXXXXXXXXXXXXXXXXERANFPSQQVSHISRSSIKIPPTSLQSLLYVSSIRYVNPKSTVNGYKSDTKSCNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNVYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDLMMSKENTFNGHWNRNYLTNAFSSNELVEHSIEMDIESLGNFLVENYSELPLKESYFYIQYYFPLQNSISDNNGKNWESAVFRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFESLGKKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLINQHSVDVDSLAETVTQQQLPVRLVNEDHGDSTYPVAVLNIRLCYRTSVVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDVRLLGSALFDLSNLILPSDQLNKSVSHILPLWKRGLNNCGNSNITVSMSICGASSPLAGYNSDNEEESNLNATKIPNNHSIQNGNGNFHRLRADHQSFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNYFVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTPTIPLVPNTAVLSKVSSSVYSPPTKPLTVEDHQSYLSSVRMRLLGQTEPLSVYPIPVSVDICPSQDIDSQDLVTKSFLFDTLKEKMRELDNLNETFXXXXXXXXXXXXXXNYEQSKESSLLNIQFTLPASKVDYGTNTEEENYEFRNQHFNNNCHSEFPYNENEIDSDEPYKDNSSDNNEKFNNYMTCINELEPIEQCGDIDMRIALDSQDFINRTNGSLSARKSESDNYSTSSCEIEQNPQMICXXXXXXXXXXXXXXPQELNEIISDHERSEISDEDQIEKQNDSWDETLPNTSYQKDEDNHSKNNLSKSVINQKSSIIGAIPKFFPQSFDFQEKMKALQRNIENNVEFKNRNPVAINGILENNSHIARQNHLLDISDHEASRISKIFGIQ 6471
MNQNINVVVNTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLEPTQLHKTLEKTYVKPIITNELNEKAELRTSLNKSHESMKPKFIDESHEIEEKSENVLDRLIETSKKIRETISIDVKDDEINDAILRKRFPDIDQATDRKWIKEILVNESVNDDFSINDPSKLHTESILKTSGDFYPSKSVRRNNHTNSDRDLIKLITVSDSFCSASVTDFPDSKYQFLNHSEADLLKKLDRDLSSDDDPCKRDSIIEELFYKQPESSSAPIMGIEAFKNKFINNECVPDLNANNSNNKKSNDFEIYKCLSRNDYENNPNEKDMIYNNYNINNNEETKHEHVEMLPNGAADRNWYNNISSVK+FLDMLWLNSTPQRCNARSRSQSSNCSTDRDRCRRSCDSASSFNNSSNSFSVTKPPTPQMFQLNPSHKYFIEYKFP NA YTADKDKENLSNSMSTTRVLVKQTGFKCNISDSNGIKSLSLDHVSEFPVTFTNSAIIQKWWRGIVRFKLICQDSNKKETVVGVGVVPLRNIISTNNFYRLIPIRLPRNKSAKSNTRMVIGSLALRTAMTLAATKGFNSSDKKPEILFQDSSDSRNQISY HPKITNIRSSNYSRSIRPSERANFPSQQVSHISRSSIKIPPTSLQSLLYVSSIRYVNPKSTVNGYKSDTKSCNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNN+YPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDLMMSKENTFNGHWNRNYLTNAFSSNELVEHSIEMDIESLGNFLVENYSELPLKESYFYIQYYFPLQNSISDNNGKNWESAVFRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFESLGKKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLINQHSVDVDSLAETVTQQQLPVRLVNEDHGDSTYPVAVLNIRLCYRTSVVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDVRLLGSALFDLSNLILPSDQLNKSVSHILPLWKRGLNNCGNSNITVSMSICGASSPLAGYNSDNEEESNLNATKIPNNHSIQNGNGNFHRLRADHQSFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNYFVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTPTIPLVPNTAVLSKVSSSVYSPPTKPLTVEDHQSYLSSVRMRLLGQTEPLSVYPIPVSVDICPSQDIDSQDLVTKSFLFDTLKEKMRELDNLNETFKKKMETKEDDTKMENYEQSKESSLLNIQFTLPASKVDYGTNTEEENYEFRNQHFNNNCHSEFPYNENEIDSDEPYKDNSSDNNEKFNNYMTCINELEPIEQCGDIDMRIALDSQDFINRTNGSL ARKSESDNYSTSSCEIEQNPQ+ICSSRSSSSCTQYSKSPQELNEIISDHERSEISDEDQIEKQNDSWDETLPNTSYQKDEDNHSKNNLSKSVINQKS IIGAIPKFFPQSFDFQEKMKALQRNIENNVEFKNRNPVAINGILENNSHIARQNHLLDISDHEASRISKIFGIQ
Sbjct: 1 MNQNINVVVNTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVAWWGEDSNGAIFVPRCVNLAGYKQNVKTHAIYPVRVPLNHFTTYLSDMSKLYVDIIDKSKHSVIGRATIDKLDQLVHNKNLQSLSGILNEKDTKIGEIMIVMTLEPTQLHKTLEKTYVKPIITNELNEKAELRTSLNKSHESMKPKFIDESHEIEEKSENVLDRLIETSKKIRETISIDVKDDEINDAILRKRFPDIDQATDRKWIKEILVNESVNDDFSINDPSKLHTESILKTSGDFYPSKSVRRNNHTNSDRDLIKLITVSDSFCSASVTDFPDSKYQFLNHSEADLLKKLDRDLSSDDDPCKRDSIIEELFYKQPESSSAPIMGIEAFKNKFINNECVPDLNANNSNNKKSNDFEIYKCLSRNDYENNPNEKDMIYNNYNINNNEETKHEHVEMLPNGAADRNWYNNISSVKVFLDMLWLNSTPQRCNARSRSQSSNCSTDRDRCRRSCDSASSFNNSSNSFSVTKPPTPQMFQLNPSHKYFIEYKFPANAPYTADKDKENLSNSMSTTRVLVKQTGFKCNISDSNGIKSLSLDHVSEFPVTFTNSAIIQKWWRGIVRFKLICQDSNKKETVVGVGVVPLRNIISTNNFYRLIPIRLPRNKSAKSNTRMVIGSLALRTAMTLAATKGFNSSDKKPEILFQDSSDSRNQISYCHPKITNIRSSNYSRSIRPSERANFPSQQVSHISRSSIKIPPTSLQSLLYVSSIRYVNPKSTVNGYKSDTKSCNLYLIGRLLWTASEKFKSRILWGASKVSDNQSVDELENFKFVEKTALILTSELLEKLKNNFSILEVWDISTDKTKQSLYGLVKIPVNIFHMSFKNEKIRKTILNNIYPLLSVDDWINIEDPISGKSKGQIHVLLAMGSPQQIEDLMMSKENTFNGHWNRNYLTNAFSSNELVEHSIEMDIESLGNFLVENYSELPLKESYFYIQYYFPLQNSISDNNGKNWESAVFRSANCQVERNVDISDTNRHRFRLPIDSSLKAILNKHFESLGKKHILFELYLKQYQPFPSSKSIAKGRLPLTSLFQLINQHSVDVDSLAETVTQQQLPVRLVNEDHGDSTYPVAVLNIRLCYRTSVVQNAVRQKTLNTSSPYDQPIIRIEMISATGLQCAAESLVSTHPELQYPSVTGVNVHVKFWLTDESNKQSRIYVNSKGIQKFQFKSTKTIPRTFTPKFDCISEVLLGPIIDDENSNCLYKTLAEKILCGIYQLNVEVYHGVFDSIYSDITEVPPSSKILIGKGRISIADLLLRSSGFMGPIWLPIFSPINSDAGLGGLKLNWPSKKNNESLYALEKRKSVGAVEVRLGFLDKSDRKTILQLAMDSGYVVPWTNRLETEDLVWQHMDNHGCTFKYITVHIEEIELSEKLVNAIFTPEVGFKKSSIKVLTRYRMFKQSISSSPNFCINEDEIAGKIFIPVNHEQQFCYRISGDLFRYLRESKLEIQAWGIYGSEARCNNDYLNDHNENPNDVRLLGSALFDLSNLILPSDQLNKSVSHILPLWKRGLNNCGNSNITVSMSICGASSPLAGYNSDNEEESNLNATKIPNNHSIQNGNGNFHRLRADHQSFPVHVIVEKAVNLKSPLFGNDSITGTELSYKPLNYFVSFPCANEDKCVTSSIIKGCKEAVWNFECDTRLPYSLLTNEKLTLDFKVYYSMSDSDSTGEILDEKVLIGIVKLDLYLLLKGFERVIGWYNIVDMQGDCQGQIKVGVTPTIPLVPNTAVLSKVSSSVYSPPTKPLTVEDHQSYLSSVRMRLLGQTEPLSVYPIPVSVDICPSQDIDSQDLVTKSFLFDTLKEKMRELDNLNETFKKKMETKEDDTKMENYEQSKESSLLNIQFTLPASKVDYGTNTEEENYEFRNQHFNNNCHSEFPYNENEIDSDEPYKDNSSDNNEKFNNYMTCINELEPIEQCGDIDMRIALDSQDFINRTNGSLCARKSESDNYSTSSCEIEQNPQLICSSRSSSSCTQYSKSPQELNEIISDHERSEISDEDQIEKQNDSWDETLPNTSYQKDEDNHSKNNLSKSVINQKSPIIGAIPKFFPQSFDFQEKMKALQRNIENNVEFKNRNPVAINGILENNSHIARQNHLLDISDHEASRISKIFGIQ 2151 The following BLAST results are available for this feature:
BLAST of C2 domain-containing protein 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of C2 domain-containing protein 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of C2 domain-containing protein 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of C2 domain-containing protein 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 3
BLAST of C2 domain-containing protein 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 2
BLAST of C2 domain-containing protein 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of C2 domain-containing protein 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 3
BLAST of C2 domain-containing protein 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of C2 domain-containing protein 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of C2 domain-containing protein 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of C2 domain-containing protein 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of C2 domain-containing protein 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of C2 domain-containing protein 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of C2 domain-containing protein 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30010766 ID=SMED30010766|Name=C2 domain-containing protein 3|organism=Schmidtea mediterranea sexual|type=transcript|length=6537bpback to top protein sequence of SMED30010766-orf-1 >SMED30010766-orf-1 ID=SMED30010766-orf-1|Name=SMED30010766-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2152bp MNQNINVVVNTSLPPSINKSEPFFYLNLHINYIKWISKVSSNYEDIIVKVback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
