UBR-type domain-containing protein

Overview
NameUBR-type domain-containing protein
Smed IDSMED30010763
Length (bp)1606
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of UBR-type domain-containing protein (SMED30010763) t-SNE clustered cells

Violin plots show distribution of expression levels for UBR-type domain-containing protein (SMED30010763) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of UBR-type domain-containing protein (SMED30010763) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for UBR-type domain-containing protein (SMED30010763) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30010763

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30010763SMESG000037081.1 SmedASXL_019427SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30010763SMESG000037081.1 SmedASXL_019427SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30010763SMESG000037081.1 dd_Smed_v4_4379_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30010763SMESG000037081.1 dd_Smed_v4_4379_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30010763SMESG000037081.1 dd_Smed_v4_4379_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Human
Match: UBR7 (ubiquitin protein ligase E3 component n-recognin 7 (putative) [Source:HGNC Symbol;Acc:HGNC:20344])

HSP 1 Score: 110.538 bits (275), Expect = 1.520e-25
Identity = 55/107 (51.40%), Postives = 67/107 (62.62%), Query Frame = 1 
Query:   91 LAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEY 411
            L G D++   C++ +G   RQALY C TC     + AGIC  CS  CH  H L +LYTKRNFRCDCGNS F  N +C+L  +K  +N  NKYN NF GLYC+C   Y
Sbjct:   38 LGGSDSEK--CSYSQGSVKRQALYACSTCTPEGEEPAGICLACSYECHGSHKLFELYTKRNFRCDCGNSKF-KNLECKLLPDKAKVNSGNKYNDNFFGLYCICKRPY 141

HSP 2 Score: 56.9954 bits (136), Expect = 5.371e-8
Identity = 24/49 (48.98%), Postives = 34/49 (69.39%), Query Frame = 2 
Query:  920 EEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALY 1066
            +EMIQCV+CEDW+H +HL A   +S     F+E VC+ C++RC +L  Y
Sbjct:  150 DEMIQCVVCEDWFHGRHLGAIPPESG---DFQEMVCQACMKRCSFLWAY 195
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Human
Match: UBR7 (ubiquitin protein ligase E3 component n-recognin 7 (putative) [Source:HGNC Symbol;Acc:HGNC:20344])

HSP 1 Score: 110.538 bits (275), Expect = 1.520e-25
Identity = 55/107 (51.40%), Postives = 67/107 (62.62%), Query Frame = 1 
Query:   91 LAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEY 411
            L G D++   C++ +G   RQALY C TC     + AGIC  CS  CH  H L +LYTKRNFRCDCGNS F  N +C+L  +K  +N  NKYN NF GLYC+C   Y
Sbjct:   38 LGGSDSEK--CSYSQGSVKRQALYACSTCTPEGEEPAGICLACSYECHGSHKLFELYTKRNFRCDCGNSKF-KNLECKLLPDKAKVNSGNKYNDNFFGLYCICKRPY 141

HSP 2 Score: 56.9954 bits (136), Expect = 5.371e-8
Identity = 24/49 (48.98%), Postives = 34/49 (69.39%), Query Frame = 2 
Query:  920 EEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALY 1066
            +EMIQCV+CEDW+H +HL A   +S     F+E VC+ C++RC +L  Y
Sbjct:  150 DEMIQCVVCEDWFHGRHLGAIPPESG---DFQEMVCQACMKRCSFLWAY 195
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Human
Match: AL110118.2 (novel protein)

HSP 1 Score: 103.99 bits (258), Expect = 2.527e-25
Identity = 51/96 (53.12%), Postives = 60/96 (62.50%), Query Frame = 1 
Query:  136 GYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESK 423
            G   RQALY C TC     + AGIC  CS  CH  H L +LYTKRNFRCDCGNS F  N +C+L  +K  +N  NKYN NF GLYC+C   Y + +
Sbjct:   70 GSVKRQALYACSTCTPEGEEPAGICLACSYECHGSHKLFELYTKRNFRCDCGNSKF-KNLECKLLPDKAKVNSGNKYNDNFFGLYCICKRPYPDPE 164
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Human
Match: AL110118.4 (novel protein)

HSP 1 Score: 103.99 bits (258), Expect = 2.527e-25
Identity = 51/96 (53.12%), Postives = 60/96 (62.50%), Query Frame = 1 
Query:  136 GYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESK 423
            G   RQALY C TC     + AGIC  CS  CH  H L +LYTKRNFRCDCGNS F  N +C+L  +K  +N  NKYN NF GLYC+C   Y + +
Sbjct:   70 GSVKRQALYACSTCTPEGEEPAGICLACSYECHGSHKLFELYTKRNFRCDCGNSKF-KNLECKLLPDKAKVNSGNKYNDNFFGLYCICKRPYPDPE 164
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Human
Match: UBR7 (ubiquitin protein ligase E3 component n-recognin 7 (putative) [Source:HGNC Symbol;Acc:HGNC:20344])

HSP 1 Score: 84.3445 bits (207), Expect = 1.640e-18
Identity = 45/111 (40.54%), Postives = 60/111 (54.05%), Query Frame = 1 
Query:   91 LAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESK 423
            L G D++   C++ +G   RQALY C TC     + AGIC  CS  CH  H L +LYTK  F+          N +C+L  +K  +N  NKYN NF GLYC+C   Y + +
Sbjct:   38 LGGSDSEK--CSYSQGSVKRQALYACSTCTPEGEEPAGICLACSYECHGSHKLFELYTKSKFK----------NLECKLLPDKAKVNSGNKYNDNFFGLYCICKRPYPDPE 136
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Celegans
Match: T22C1.1 (pep chromosome:WBcel235:I:7936264:7937865:1 gene:WBGene00011912.1 transcript:T22C1.1.3 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T22C1.1)

HSP 1 Score: 105.531 bits (262), Expect = 1.262e-24
Identity = 53/129 (41.09%), Postives = 82/129 (63.57%), Query Frame = 1 
Query:   40 EEDTISFQEI-----YDYETRNLAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEY 411
            EE+ ++  EI     Y  +  ++     + + CT+ +GY  RQ L+ CLTC   + + AG+C+ C+++CH GH++ +LYTKR F+CDCGNS F +  KC L+E+KD  N  N YNHN++G +C C+  Y
Sbjct:   19 EEEAVTLGEIVETIDYLEDKADVLFATQNPNVCTYAEGYKPRQTLFTCLTCTP-APEMAGVCYGCALNCHDGHIIVELYTKRKFKCDCGNSKFGEK-KCALYEDKDAKNEYNMYNHNYNGKFCTCDVFY 145

HSP 2 Score: 62.003 bits (149), Expect = 3.987e-10
Identity = 55/226 (24.34%), Postives = 93/226 (41.15%), Query Frame = 2 
Query:  920 EEMIQCVICEDWYHLKHLA-----------ASGSDSQPLEHFEEFVCKLCLERCEYLALYNRASVNKVLGKYIAADGNCNLEAARAALEQLGNNCEEPGSLSGNNGGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYYYTNDQEKF-------NDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNN---GGPDKVVTTEDVHNFFDKIKRRRLEK 1534
            +E++QC ICEDW+H +H+             + SD+         VC +C+++  +L             K IA +                    EP +L   +        +R  LC+CA C ++ +  +  FL +  D IA + +  ++K        +DE +E +  +    A      +  FKR+L +FLN    GG  + +   D+  FFD +K   LEK
Sbjct:  152 KELLQCEICEDWFHEEHMPFKDVNYYYEEIEANSDTILNRDIASAVCLVCIKKLPFLMHMKSGKDVFCHSKLIAEETK-----------------PEPHALCIEH--------FRAKLCKCADCVRVYEMADCEFLLDDEDDIATFDSESRKKVEENKTTEDDEMREMVKQIGMDGAQHFYSEVHNFKRKLEDFLNTKAEGG--RTIAASDIKTFFDALKEENLEK 350
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Celegans
Match: T22C1.1 (pep chromosome:WBcel235:I:7936223:7938328:1 gene:WBGene00011912.1 transcript:T22C1.1.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T22C1.1)

HSP 1 Score: 105.531 bits (262), Expect = 1.262e-24
Identity = 53/129 (41.09%), Postives = 82/129 (63.57%), Query Frame = 1 
Query:   40 EEDTISFQEI-----YDYETRNLAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEY 411
            EE+ ++  EI     Y  +  ++     + + CT+ +GY  RQ L+ CLTC   + + AG+C+ C+++CH GH++ +LYTKR F+CDCGNS F +  KC L+E+KD  N  N YNHN++G +C C+  Y
Sbjct:   19 EEEAVTLGEIVETIDYLEDKADVLFATQNPNVCTYAEGYKPRQTLFTCLTCTP-APEMAGVCYGCALNCHDGHIIVELYTKRKFKCDCGNSKFGEK-KCALYEDKDAKNEYNMYNHNYNGKFCTCDVFY 145

HSP 2 Score: 62.003 bits (149), Expect = 3.987e-10
Identity = 55/226 (24.34%), Postives = 93/226 (41.15%), Query Frame = 2 
Query:  920 EEMIQCVICEDWYHLKHLA-----------ASGSDSQPLEHFEEFVCKLCLERCEYLALYNRASVNKVLGKYIAADGNCNLEAARAALEQLGNNCEEPGSLSGNNGGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYYYTNDQEKF-------NDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNN---GGPDKVVTTEDVHNFFDKIKRRRLEK 1534
            +E++QC ICEDW+H +H+             + SD+         VC +C+++  +L             K IA +                    EP +L   +        +R  LC+CA C ++ +  +  FL +  D IA + +  ++K        +DE +E +  +    A      +  FKR+L +FLN    GG  + +   D+  FFD +K   LEK
Sbjct:  152 KELLQCEICEDWFHEEHMPFKDVNYYYEEIEANSDTILNRDIASAVCLVCIKKLPFLMHMKSGKDVFCHSKLIAEETK-----------------PEPHALCIEH--------FRAKLCKCADCVRVYEMADCEFLLDDEDDIATFDSESRKKVEENKTTEDDEMREMVKQIGMDGAQHFYSEVHNFKRKLEDFLNTKAEGG--RTIAASDIKTFFDALKEENLEK 350
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Celegans
Match: T22C1.1 (pep chromosome:WBcel235:I:7936264:7938328:1 gene:WBGene00011912.1 transcript:T22C1.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T22C1.1)

HSP 1 Score: 105.531 bits (262), Expect = 1.262e-24
Identity = 53/129 (41.09%), Postives = 82/129 (63.57%), Query Frame = 1 
Query:   40 EEDTISFQEI-----YDYETRNLAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEY 411
            EE+ ++  EI     Y  +  ++     + + CT+ +GY  RQ L+ CLTC   + + AG+C+ C+++CH GH++ +LYTKR F+CDCGNS F +  KC L+E+KD  N  N YNHN++G +C C+  Y
Sbjct:   19 EEEAVTLGEIVETIDYLEDKADVLFATQNPNVCTYAEGYKPRQTLFTCLTCTP-APEMAGVCYGCALNCHDGHIIVELYTKRKFKCDCGNSKFGEK-KCALYEDKDAKNEYNMYNHNYNGKFCTCDVFY 145

HSP 2 Score: 62.003 bits (149), Expect = 3.987e-10
Identity = 55/226 (24.34%), Postives = 93/226 (41.15%), Query Frame = 2 
Query:  920 EEMIQCVICEDWYHLKHLA-----------ASGSDSQPLEHFEEFVCKLCLERCEYLALYNRASVNKVLGKYIAADGNCNLEAARAALEQLGNNCEEPGSLSGNNGGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYYYTNDQEKF-------NDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNN---GGPDKVVTTEDVHNFFDKIKRRRLEK 1534
            +E++QC ICEDW+H +H+             + SD+         VC +C+++  +L             K IA +                    EP +L   +        +R  LC+CA C ++ +  +  FL +  D IA + +  ++K        +DE +E +  +    A      +  FKR+L +FLN    GG  + +   D+  FFD +K   LEK
Sbjct:  152 KELLQCEICEDWFHEEHMPFKDVNYYYEEIEANSDTILNRDIASAVCLVCIKKLPFLMHMKSGKDVFCHSKLIAEETK-----------------PEPHALCIEH--------FRAKLCKCADCVRVYEMADCEFLLDDEDDIATFDSESRKKVEENKTTEDDEMREMVKQIGMDGAQHFYSEVHNFKRKLEDFLNTKAEGG--RTIAASDIKTFFDALKEENLEK 350
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Celegans
Match: ubr-4 (UBR E3 ubiquitin ligase homolog [Source:UniProtKB/TrEMBL;Acc:Q7KQG4])

HSP 1 Score: 49.6766 bits (117), Expect = 7.063e-6
Identity = 38/118 (32.20%), Postives = 57/118 (48.31%), Query Frame = 1 
Query:  109 DDSCCTFPK-GYAY-RQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKR-NFRCDCGNS---------NFPD---NFKCQLWEEKDDIN---IKNKYNHNFSGLYCVCNSE 408
            D + CT+   G AY  Q  Y+C TC  +  +  G+C  C+++CH GH L   Y+K+ +F CDCG           + P+   + + QL E+  D     I+N + H F  L   C  E
Sbjct: 1219 DLNFCTYKSTGRAYVTQHWYNCYTCNMMESE--GVCSVCAINCHRGHDLA--YSKKGSFFCDCGEKKCGAMQGIYHLPNSMYSLRGQLPEKNGDKTLPKIRNVFEHRFENLNSNCCDE 1332
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Celegans
Match: ubr-4 (UBR E3 ubiquitin ligase homolog [Source:UniProtKB/TrEMBL;Acc:Q7KQG4])

HSP 1 Score: 49.6766 bits (117), Expect = 7.123e-6
Identity = 38/118 (32.20%), Postives = 57/118 (48.31%), Query Frame = 1 
Query:  109 DDSCCTFPK-GYAY-RQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKR-NFRCDCGNS---------NFPD---NFKCQLWEEKDDIN---IKNKYNHNFSGLYCVCNSE 408
            D + CT+   G AY  Q  Y+C TC  +  +  G+C  C+++CH GH L   Y+K+ +F CDCG           + P+   + + QL E+  D     I+N + H F  L   C  E
Sbjct: 1212 DLNFCTYKSTGRAYVTQHWYNCYTCNMMESE--GVCSVCAINCHRGHDLA--YSKKGSFFCDCGEKKCGAMQGIYHLPNSMYSLRGQLPEKNGDKTLPKIRNVFEHRFENLNSNCCDE 1325
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Fly
Match: CG15141 (gene:FBgn0032635 transcript:FBtr0080979)

HSP 1 Score: 98.5969 bits (244), Expect = 6.039e-22
Identity = 60/144 (41.67%), Postives = 76/144 (52.78%), Query Frame = 1 
Query:   19 MAESENLEEDTISFQEIYDYETR------NLAGCDNDDSCCTFPKGYAYRQALYHCLTC----REISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDI---NIKNKYNHNFSGLYCVCNSEY 411
            + ES  LE+ TI+  ++ + E         + G  +D+  CT+ KG   RQALY CLTC    RE   K AG+C  CS  CH  H L +LYTKRNFRCDC         KC L  + + +   N+ N YN NF GLYC C   Y
Sbjct:   13 VEESNPLEQSTITMLDVLEQEKELEDEYAAVLGA-SDEKSCTYAKGPIGRQALYSCLTCCPEAREDLDKAAGVCLACSYRCHEHHELVELYTKRNFRCDCPTQRL---GKCSLNPQVEGVQPRNVGNLYNQNFQGLYCKCKRPY 152

HSP 2 Score: 91.6633 bits (226), Expect = 1.178e-19
Identity = 62/226 (27.43%), Postives = 99/226 (43.81%), Query Frame = 2 
Query:  920 EEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALYNRASVNKVL-----GKYIAADGNCNLEAARAALEQLG--------------------NNCEEPGSLSGNNGGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYYYTNDQEKF--NDEFKEQMSTMPHAVAIKLADGIAYFKR---ELIEFLNN-GGPDKVVTTEDVHNFF 1504
            E M+QC ICEDW+HL H+ A G+  + L+   E +C  C++   +L  Y   ++  VL      K  A D     E  R+  + +                     ++C  P     + G AFW +DWR+SLC+C+ C  L K     FL +  D+   Y     ++   N  +++ +  +      +  D I  + R   +L E+L       KVVT ED++ FF
Sbjct:  161 EVMLQCAICEDWFHLPHMKAPGASDKWLDVCSEMICDGCMDAKPFLKDYTGLALQPVLEDAKEDKPEADDSQLKNELDRSICDIMKVPEGESQPDEGEPSQKRAKLDDCRRPKPTKEHQGAAFWTNDWRKSLCQCSECLSLYKELAVEFLLDVEDSAKTYEERGMKRAEENSSYEQGIRALASIDRTQQIDAITEYNRMKDKLKEYLQAFAASKKVVTEEDINRFF 386
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Zebrafish
Match: ubr7 (ubiquitin protein ligase E3 component n-recognin 7 [Source:ZFIN;Acc:ZDB-GENE-030131-1535])

HSP 1 Score: 120.553 bits (301), Expect = 3.045e-29
Identity = 58/111 (52.25%), Postives = 75/111 (67.57%), Query Frame = 1 
Query:   91 LAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESK 423
            L G D++   C++P+GY  RQALY C TC    G+ AGIC  CS  CH GH L +LYTKRNFRCDCGN  F D  +C+L+ +K+ +N  NKY+HNF GLYC C+  Y + +
Sbjct:   31 LGGSDSEK--CSYPEGYVKRQALYACNTCTPKGGEPAGICLACSYKCHEGHDLFELYTKRNFRCDCGNDKFGD-MECKLFADKEKVNSGNKYSHNFFGLYCTCDRPYPDPE 138

HSP 2 Score: 56.6102 bits (135), Expect = 3.592e-8
Identity = 57/262 (21.76%), Postives = 98/262 (37.40%), Query Frame = 2 
Query:  917 TEEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALY-NRASVNKVL---------------------------GKYIAADGNCNLEAARAALEQLGNNCE----------------EPGSLSGNNGGAFW-PSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYY-----YTNDQEKFN-----DEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNN-GGPDKVVTTEDVHNFFDKIKRRRLEK 1534
            ++EMIQC++CEDW H +HL  +  D   L   +E +C+ C+ +  +L  Y  + +V+ ++                               A D    +        +L +  E                +   +S    GA + PS WR  LC C  C+ L       FL +  DT+  Y      T   E+       D     ++ +     +++       K EL ++L       KVVT ED+  FF++ + R+  +
Sbjct:  142 SDEMIQCIVCEDWLHGRHLGCAVPDCVEL---QEMICESCMNKTPFLWNYAAQIAVSPIIKVSPCKAEEDVKVEVEKEEEEKMVKNENTKSAVDEKVQMNGTSGCKRKLQDESEGSSGHGLCSGCRLREMKASGISRKQQGAVFWPSAWRTKLCSCPDCKVLYADAGLCFLTDEADTVLAYENKGKSTEQAEQAGGAGGRDPLMSALNNLNRVQQLEIIHEYNDMKTELKDYLQRFAAEGKVVTPEDIRQFFEQQQSRKRRR 400
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Zebrafish
Match: CABZ01066926.1 (putative E3 ubiquitin-protein ligase UBR7 [Source:NCBI gene;Acc:100329344])

HSP 1 Score: 74.3294 bits (181), Expect = 3.371e-14
Identity = 60/226 (26.55%), Postives = 98/226 (43.36%), Query Frame = 2 
Query:  911 QDTEEMIQCVICEDWYHLKHLAASGSDSQPL--EHFEEFVCKLCLERCEYL----ALYNRASVNKVLG--KYIAADGNCNLE----------AARAALEQLGNNC-----EEPGSLSGNNGGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYY---YTNDQEKFNDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNNGG-PDKVVTTEDVHNFFD 1507
            Q  +EM+QCV+CEDW+H KHL A      PL  +   E VC  C++R  +L    A ++ ++VN  +   +  AA   C  E           A + L      C     ++  + +  +G  FWP DWR  LC C  C+++       FL + +DT+  Y      +  +        ++T+ H   +     +   K+EL EFL       + +T E +  F +
Sbjct:   75 QVNDEMVQCVVCEDWFHEKHLQAP-----PLCCDSLTEMVCVGCMKRVPFLWTYAAHFSVSAVNSAVSSRETTAASVCCQQEAAAASADAGVCAASPLCSGSGVCVFTKLKDTETHTDQHGSVFWPYDWRSKLCTCTDCKRMYVASGVQFLLDESDTVLAYEDRAKTEALRSGGGVLSCLNTLTHQQQLDTLYRLNEMKQELCEFLQQCSEQSQQLTPEGLQEFLE 295

HSP 2 Score: 64.3142 bits (155), Expect = 8.224e-11
Identity = 28/53 (52.83%), Postives = 36/53 (67.92%), Query Frame = 1 
Query:  262 TKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDES 420
             +R+FRCDCGN  FP  F C+L   KD  N+KN YNHN+SG YC C+  Y ++
Sbjct:   21 ARRSFRCDCGNEKFP-GFSCRLHANKDGRNVKNSYNHNYSGRYCSCDRPYPDT 72
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Zebrafish
Match: ubr7 (ubiquitin protein ligase E3 component n-recognin 7 [Source:ZFIN;Acc:ZDB-GENE-030131-1535])

HSP 1 Score: 50.0618 bits (118), Expect = 2.426e-6
Identity = 33/122 (27.05%), Postives = 51/122 (41.80%), Query Frame = 2 
Query: 1202 GGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYY-----YTNDQEKFN-----DEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNN-GGPDKVVTTEDVHNFFDKIKRRRLEK 1534
            G  FWPS WR  LC C  C+ L       FL +  DT+  Y      T   E+       D     ++ +     +++       K EL ++L       KVVT ED+  FF++ + R+  +
Sbjct:  104 GAVFWPSAWRTKLCSCPDCKVLYADAGLCFLTDEADTVLAYENKGKSTEQAEQAGGAGGRDPLMSALNNLNRVQQLEIIHEYNDMKTELKDYLQRFAAEGKVVTPEDIRQFFEQQQSRKRRR 225
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Xenopus
Match: pbx1 (pre-B-cell leukemia homeobox 1 [Source:Xenbase;Acc:XB-GENE-1217592])

HSP 1 Score: 113.235 bits (282), Expect = 7.840e-27
Identity = 59/139 (42.45%), Postives = 81/139 (58.27%), Query Frame = 1 
Query:    7 ISNIMAESENLEEDTISFQEIYDYETRNLAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESK 423
            + +++ E + LE++  +           L  CD +   C++P+GY  RQALY C TC       AGIC  CS  CH GH L +LYTKRNFRCDCGN+ F    +C+L+ EK++ N  NKYN NF G+YC C   Y + +
Sbjct:   22 LLDVLEEDDALEDEACAV----------LGACDAEK--CSYPEGYVRRQALYACNTCTPNKEDPAGICLACSYKCHEGHDLFELYTKRNFRCDCGNAKF-KQLECKLFSEKENSNSLNKYNQNFFGVYCTCKRPYPDPE 147

HSP 2 Score: 110.923 bits (276), Expect = 5.848e-26
Identity = 74/224 (33.04%), Postives = 111/224 (49.55%), Query Frame = 2 
Query:  920 EEMIQCVICEDWYHLKHLAASGSDSQPLEH--FEEFVCKLCLERCEYLALYNRASVNKVLGKYIA---ADGN----CNLEAARAALEQLGNNCEEPGSLSGNNGGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYY----YTNDQEKFNDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNNGGPD-KVVTTEDVHNFFDKI---KRRRLEKFE 1540
            +EMIQC++CEDW+H +HL A      P EH  FEE VC+ C++RC +L  Y     +K    ++    ADG        EA   ++ +L      P  +S  N   +WPS+WR  LC C  C+ +  + E  FL + NDT+  Y     T    +  D     +S+M     ++L       K EL ++L     + KVV TED+  FF+++   KRRRL+  +
Sbjct:  152 DEMIQCIVCEDWFHGRHLGAV-----PPEHMDFEEMVCQTCMDRCSFLWTYAAHIASKAYIIFLVEKCADGKDSHLLKTEANAQSVCKLQEMKMHP--VSKANTATYWPSNWRSKLCTCDDCKNMYTKFEVLFLLDENDTVQAYENKGKTQQATERRDPLMTALSSMNRVQQVELICEYNDLKTELTDYLKRFAEEGKVVKTEDIQQFFEELRSRKRRRLDGMQ 368
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Xenopus
Match: pbx1 (pre-B-cell leukemia homeobox 1 [Source:Xenbase;Acc:XB-GENE-1217592])

HSP 1 Score: 113.235 bits (282), Expect = 8.325e-27
Identity = 59/139 (42.45%), Postives = 81/139 (58.27%), Query Frame = 1 
Query:    7 ISNIMAESENLEEDTISFQEIYDYETRNLAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESK 423
            + +++ E + LE++  +           L  CD +   C++P+GY  RQALY C TC       AGIC  CS  CH GH L +LYTKRNFRCDCGN+ F    +C+L+ EK++ N  NKYN NF G+YC C   Y + +
Sbjct:   13 LLDVLEEDDALEDEACAV----------LGACDAEK--CSYPEGYVRRQALYACNTCTPNKEDPAGICLACSYKCHEGHDLFELYTKRNFRCDCGNAKF-KQLECKLFSEKENSNSLNKYNQNFFGVYCTCKRPYPDPE 138

HSP 2 Score: 105.145 bits (261), Expect = 6.183e-24
Identity = 74/234 (31.62%), Postives = 111/234 (47.44%), Query Frame = 2 
Query:  920 EEMIQCVICEDWYHLKHLAASGSDSQPLEH--FEEFVCKLCLERCEYLALYNRASVNKVLGKYI--AADGNCNL------------------EAARAALEQLGNNCEEPGSLSGNNGGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYY----YTNDQEKFNDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNNGGPD-KVVTTEDVHNFFDKI---KRRRLE 1531
            +EMIQC++CEDW+H +HL A      P EH  FEE VC+ C++RC +L  Y     +K    ++  A   +C L                  EA   ++ +L      P  +S  N   +WPS+WR  LC C  C+ +  + E  FL + NDT+  Y     T    +  D     +S+M     ++L       K EL ++L     + KVV TED+  FF+++   KRRRL+
Sbjct:  143 DEMIQCIVCEDWFHGRHLGAV-----PPEHMDFEEMVCQTCMDRCSFLWTYAAHIASKAYIIFLVEAFYFSCTLLFFPQYYIYVFDSHLLKTEANAQSVCKLQEMKMHP--VSKANTATYWPSNWRSKLCTCDDCKNMYTKFEVLFLLDENDTVQAYENKGKTQQATERRDPLMTALSSMNRVQQVELICEYNDLKTELTDYLKRFAEEGKVVKTEDIQQFFEELRSRKRRRLD 369
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Xenopus
Match: pbx1 (pre-B-cell leukemia homeobox 1 [Source:Xenbase;Acc:XB-GENE-1217592])

HSP 1 Score: 113.235 bits (282), Expect = 9.298e-27
Identity = 59/139 (42.45%), Postives = 81/139 (58.27%), Query Frame = 1 
Query:    7 ISNIMAESENLEEDTISFQEIYDYETRNLAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESK 423
            + +++ E + LE++  +           L  CD +   C++P+GY  RQALY C TC       AGIC  CS  CH GH L +LYTKRNFRCDCGN+ F    +C+L+ EK++ N  NKYN NF G+YC C   Y + +
Sbjct:   27 LLDVLEEDDALEDEACAV----------LGACDAEK--CSYPEGYVRRQALYACNTCTPNKEDPAGICLACSYKCHEGHDLFELYTKRNFRCDCGNAKF-KQLECKLFSEKENSNSLNKYNQNFFGVYCTCKRPYPDPE 152

HSP 2 Score: 110.538 bits (275), Expect = 7.394e-26
Identity = 74/224 (33.04%), Postives = 111/224 (49.55%), Query Frame = 2 
Query:  920 EEMIQCVICEDWYHLKHLAASGSDSQPLEH--FEEFVCKLCLERCEYLALYNRASVNKVLGKYIA---ADGN----CNLEAARAALEQLGNNCEEPGSLSGNNGGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYY----YTNDQEKFNDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNNGGPD-KVVTTEDVHNFFDKI---KRRRLEKFE 1540
            +EMIQC++CEDW+H +HL A      P EH  FEE VC+ C++RC +L  Y     +K    ++    ADG        EA   ++ +L      P  +S  N   +WPS+WR  LC C  C+ +  + E  FL + NDT+  Y     T    +  D     +S+M     ++L       K EL ++L     + KVV TED+  FF+++   KRRRL+  +
Sbjct:  157 DEMIQCIVCEDWFHGRHLGAV-----PPEHMDFEEMVCQTCMDRCSFLWTYAAHIASKAYIIFLVEKCADGKDSHLLKTEANAQSVCKLQEMKMHP--VSKANTATYWPSNWRSKLCTCDDCKNMYTKFEVLFLLDENDTVQAYENKGKTQQATERRDPLMTALSSMNRVQQVELICEYNDLKTELTDYLKRFAEEGKVVKTEDIQQFFEELRSRKRRRLDGMQ 373
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Xenopus
Match: pbx1 (pre-B-cell leukemia homeobox 1 [Source:Xenbase;Acc:XB-GENE-1217592])

HSP 1 Score: 113.235 bits (282), Expect = 1.059e-26
Identity = 59/139 (42.45%), Postives = 81/139 (58.27%), Query Frame = 1 
Query:    7 ISNIMAESENLEEDTISFQEIYDYETRNLAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESK 423
            + +++ E + LE++  +           L  CD +   C++P+GY  RQALY C TC       AGIC  CS  CH GH L +LYTKRNFRCDCGN+ F    +C+L+ EK++ N  NKYN NF G+YC C   Y + +
Sbjct:   17 LLDVLEEDDALEDEACAV----------LGACDAEK--CSYPEGYVRRQALYACNTCTPNKEDPAGICLACSYKCHEGHDLFELYTKRNFRCDCGNAKF-KQLECKLFSEKENSNSLNKYNQNFFGVYCTCKRPYPDPE 142

HSP 2 Score: 103.99 bits (258), Expect = 1.359e-23
Identity = 74/240 (30.83%), Postives = 110/240 (45.83%), Query Frame = 2 
Query:  920 EEMIQCVICEDWYHLKHLAASGSDSQPLEH--FEEFVCKLCLERCEYLALYNRASVNKVLGKYIA----------------------ADGN----CNLEAARAALEQLGNNCEEPGSLSGNNGGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYY----YTNDQEKFNDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNNGGPD-KVVTTEDVHNFFDKI---KRRRLE 1531
            +EMIQC++CEDW+H +HL A      P EH  FEE VC+ C++RC +L  Y     +K    ++                       ADG        EA   ++ +L      P  +S  N   +WPS+WR  LC C  C+ +  + E  FL + NDT+  Y     T    +  D     +S+M     ++L       K EL ++L     + KVV TED+  FF+++   KRRRL+
Sbjct:  147 DEMIQCIVCEDWFHGRHLGAV-----PPEHMDFEEMVCQTCMDRCSFLWTYAAHIASKAYIIFLVEAFYFSCTLLFFPQYYIYVFKCADGKDSHLLKTEANAQSVCKLQEMKMHP--VSKANTATYWPSNWRSKLCTCDDCKNMYTKFEVLFLLDENDTVQAYENKGKTQQATERRDPLMTALSSMNRVQQVELICEYNDLKTELTDYLKRFAEEGKVVKTEDIQQFFEELRSRKRRRLD 379
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Xenopus
Match: pbx1 (pre-B-cell leukemia homeobox 1 [Source:Xenbase;Acc:XB-GENE-1217592])

HSP 1 Score: 113.62 bits (283), Expect = 1.215e-26
Identity = 56/111 (50.45%), Postives = 70/111 (63.06%), Query Frame = 1 
Query:   91 LAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESK 423
            L  CD +   C++P+GY  RQALY C TC       AGIC  CS  CH GH L +LYTKRNFRCDCGN+ F    +C+L+ EK++ N  NKYN NF G+YC C   Y + +
Sbjct:   40 LGACDAEK--CSYPEGYVRRQALYACNTCTPNKEDPAGICLACSYKCHEGHDLFELYTKRNFRCDCGNAKF-KQLECKLFSEKENSNSLNKYNQNFFGVYCTCKRPYPDPE 147

HSP 2 Score: 97.8265 bits (242), Expect = 2.688e-21
Identity = 73/261 (27.97%), Postives = 109/261 (41.76%), Query Frame = 2 
Query:  920 EEMIQCVICEDWYHLKHLAASGSDSQPLEH--FEEFVCKLCLERCEYLALY------NRASVNKVLGKYIAADGNCNLEAARAALE-----------------QLGNNCEEPGSL---------------------SGNNGGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYY----YTNDQEKFNDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNNGGPD-KVVTTEDVHNFFDKI---KRRRLEKFE 1540
            +EMIQC++CEDW+H +HL A      P EH  FEE VC+ C++RC +L  Y          V+  L + I      N++  +   E                       E+   L                     S  N   +WPS+WR  LC C  C+ +  + E  FL + NDT+  Y     T    +  D     +S+M     ++L       K EL ++L     + KVV TED+  FF+++   KRRRL+  +
Sbjct:  152 DEMIQCIVCEDWFHGRHLGAV-----PPEHMDFEEMVCQTCMDRCSFLWTYAAHIASKDIKVDDSLAEGILDGDGSNIKTEKLKEEITACVIKEEEINKTNGASTSTETEQDSHLLKTEANAQSVCKLQEMKMHPVSKANTATYWPSNWRSKLCTCDDCKNMYTKFEVLFLLDENDTVQAYENKGKTQQATERRDPLMTALSSMNRVQQVELICEYNDLKTELTDYLKRFAEEGKVVKTEDIQQFFEELRSRKRRRLDGMQ 407
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Mouse
Match: Ubr7 (ubiquitin protein ligase E3 component n-recognin 7 (putative) [Source:MGI Symbol;Acc:MGI:1913872])

HSP 1 Score: 110.153 bits (274), Expect = 1.333e-25
Identity = 56/111 (50.45%), Postives = 70/111 (63.06%), Query Frame = 1 
Query:   91 LAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESK 423
            L G D++   C++ +G   RQALY C TC     + AGIC  CS  CH  H L +LYTKRNFRCDCGNS F  N +C+L+ +K  +N  NKYN NF GLYCVC   Y + +
Sbjct:   38 LGGSDSEK--CSYSQGSVGRQALYACSTCTPEGEEPAGICLACSYECHGSHKLFELYTKRNFRCDCGNSKF-KNLECKLFPDKSKVNSCNKYNDNFFGLYCVCKRPYPDPE 145

HSP 2 Score: 56.6102 bits (135), Expect = 5.103e-8
Identity = 24/49 (48.98%), Postives = 33/49 (67.35%), Query Frame = 2 
Query:  920 EEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALY 1066
            +EMIQCV+CEDW+H +HL A   +S     F+E VC+ C+ RC +L  Y
Sbjct:  150 DEMIQCVVCEDWFHGRHLGAIPPESG---DFQEMVCQACMRRCSFLWAY 195

HSP 3 Score: 52.373 bits (124), Expect = 1.006e-6
Identity = 34/122 (27.87%), Postives = 55/122 (45.08%), Query Frame = 2 
Query: 1199 NGGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYYYT---NDQ-EKFNDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNN-GGPDKVVTTEDVHNFFDKI---KRRRLEKFE 1540
            +   +WP +WR  LC C  C ++    +  FL +  DT+  Y     NDQ     D   + +S+M     ++L       K EL ++L        VV  ED+  FF++    KRRR++  +
Sbjct:  300 DAATYWPLNWRSKLCTCQDCMKMYGELDVLFLTDECDTVLAYENKGKNDQATDRRDPLMDTLSSMNRVQQVELICEYNDLKTELKDYLKRFADEGTVVKREDIQQFFEEFQSKKRRRVDGLQ 421
[Close]
BLAST of UBR-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8N806|UBR7_HUMAN (Putative E3 ubiquitin-protein ligase UBR7 OS=Homo sapiens OX=9606 GN=UBR7 PE=1 SV=2)

HSP 1 Score: 110.538 bits (275), Expect = 7.301e-25
Identity = 55/107 (51.40%), Postives = 67/107 (62.62%), Query Frame = 1 
Query:   91 LAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEY 411
            L G D++   C++ +G   RQALY C TC     + AGIC  CS  CH  H L +LYTKRNFRCDCGNS F  N +C+L  +K  +N  NKYN NF GLYC+C   Y
Sbjct:   38 LGGSDSEK--CSYSQGSVKRQALYACSTCTPEGEEPAGICLACSYECHGSHKLFELYTKRNFRCDCGNSKF-KNLECKLLPDKAKVNSGNKYNDNFFGLYCICKRPY 141

HSP 2 Score: 56.9954 bits (136), Expect = 2.579e-7
Identity = 24/49 (48.98%), Postives = 34/49 (69.39%), Query Frame = 2 
Query:  920 EEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALY 1066
            +EMIQCV+CEDW+H +HL A   +S     F+E VC+ C++RC +L  Y
Sbjct:  150 DEMIQCVVCEDWFHGRHLGAIPPESG---DFQEMVCQACMKRCSFLWAY 195
[Close]
BLAST of UBR-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8BU04|UBR7_MOUSE (Putative E3 ubiquitin-protein ligase UBR7 OS=Mus musculus OX=10090 GN=Ubr7 PE=1 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 9.325e-25
Identity = 56/111 (50.45%), Postives = 70/111 (63.06%), Query Frame = 1 
Query:   91 LAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESK 423
            L G D++   C++ +G   RQALY C TC     + AGIC  CS  CH  H L +LYTKRNFRCDCGNS F  N +C+L+ +K  +N  NKYN NF GLYCVC   Y + +
Sbjct:   38 LGGSDSEK--CSYSQGSVGRQALYACSTCTPEGEEPAGICLACSYECHGSHKLFELYTKRNFRCDCGNSKF-KNLECKLFPDKSKVNSCNKYNDNFFGLYCVCKRPYPDPE 145

HSP 2 Score: 56.6102 bits (135), Expect = 3.570e-7
Identity = 24/49 (48.98%), Postives = 33/49 (67.35%), Query Frame = 2 
Query:  920 EEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALY 1066
            +EMIQCV+CEDW+H +HL A   +S     F+E VC+ C+ RC +L  Y
Sbjct:  150 DEMIQCVVCEDWFHGRHLGAIPPESG---DFQEMVCQACMRRCSFLWAY 195

HSP 3 Score: 52.373 bits (124), Expect = 7.036e-6
Identity = 34/122 (27.87%), Postives = 55/122 (45.08%), Query Frame = 2 
Query: 1199 NGGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYYYT---NDQ-EKFNDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNN-GGPDKVVTTEDVHNFFDKI---KRRRLEKFE 1540
            +   +WP +WR  LC C  C ++    +  FL +  DT+  Y     NDQ     D   + +S+M     ++L       K EL ++L        VV  ED+  FF++    KRRR++  +
Sbjct:  300 DAATYWPLNWRSKLCTCQDCMKMYGELDVLFLTDECDTVLAYENKGKNDQATDRRDPLMDTLSSMNRVQQVELICEYNDLKTELKDYLKRFADEGTVVKREDIQQFFEEFQSKKRRRVDGLQ 421
[Close]
BLAST of UBR-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q09329|MLO2_SCHPO (Protein mlo2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=mlo2 PE=2 SV=1)

HSP 1 Score: 94.7449 bits (234), Expect = 5.380e-20
Identity = 44/98 (44.90%), Postives = 63/98 (64.29%), Query Frame = 1 
Query:  121 CTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYD 414
            CT+  GY  +Q LY CLTC++ SG    +C+ CS+ CHA H L DL+ KR+FRCDCG +    +  C L +  D+   +N YNHNF G +C+C++ Y+
Sbjct:   35 CTYSMGY-LKQPLYACLTCQKASGSLNAVCYSCSISCHADHDLVDLFNKRHFRCDCGTTR-THSIPCNLRKSVDECGSENDYNHNFEGRFCICDTVYN 130
[Close]
BLAST of UBR-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q54DV0|UBR7_DICDI (Putative E3 ubiquitin-protein ligase ubr7 OS=Dictyostelium discoideum OX=44689 GN=ubr7 PE=3 SV=2)

HSP 1 Score: 77.7962 bits (190), Expect = 5.653e-14
Identity = 52/151 (34.44%), Postives = 70/151 (46.36%), Query Frame = 1 
Query:  109 DDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNS-NFPDN-FKCQL-----------------------------------------------WEEKDDINIKNKYNHNFSGLYCVCNSEYD 414
            D+S CTF KGY   Q+++ C TC+  + K  G C+ CS+HCH  H + +L+ KRNFRCDCG     P+N FKCQL                                               +++   +N +N YNHNF G YC C+S YD
Sbjct:   98 DESICTFDKGYI-NQSVFACKTCQLSNDKLFGFCYGCSMHCHLYHDVYELFNKRNFRCDCGTKIQEPNNSFKCQLSGILKEDDNNNVNNINNSNNTTTTTTTTTTTTTTTNNNHLNDIDIGSYDKSQILNERNHYNHNFKGKYCYCDSPYD 247

HSP 2 Score: 56.6102 bits (135), Expect = 3.035e-7
Identity = 52/212 (24.53%), Postives = 87/212 (41.04%), Query Frame = 2 
Query:  920 EEMIQCVICEDWYHLK--HLAASGSDSQPLEHFEEFVCKLCLERCEYLALYNRASVNKVLGKYIAADGNCNLEAARAALEQLGNNCE-EPGSLSGNNG-GAFWPSDWRESLCRCASCQQLMKRDETGF--------LHNANDTIAYYYTNDQ----EKFNDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNNG-GPDKVVTTEDVHNFF 1504
            E+MIQC+ CEDW+H     L ++ +D      F + +C  CL + ++L LY +          I  D                + C+ E G ++ N     F    W++ LC C  C+++ K  +  F        L   N T+     N      E   D F +   T+P      L +G +  K +L E  +     ++V+T +D+ +FF
Sbjct:  250 EDMIQCIFCEDWFHENCLKLNSNVTDIPSPGEFSDLICADCLSKNQFLLLYPQIRCYIENDHIIIGD----NNNNNNNSNNSNSICKVEGGVITPNKKYDLFCKELWKDELCSCLKCKEIYKDKKVEFLFEKDENSLKKKNKTVDENLDNKPVNVFEMGQDVFSK---TLPPTQQRALIEGFSDMKEKLKELFSKKLDKNQVITKQDIQSFF 454
[Close]
BLAST of UBR-type domain-containing protein vs. TrEMBL
Match: A0A0R3W7I5 (UBR-type domain-containing protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS6243 PE=4 SV=1)

HSP 1 Score: 142.895 bits (359), Expect = 4.896e-34
Identity = 64/127 (50.39%), Postives = 87/127 (68.50%), Query Frame = 1 
Query:   55 SFQEIYDYETRNLA----GCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESK 423
            +  EI   ET   A      ++++  CTFPKGY  RQA++ C TC E++GK+AG+C+ CS+HCHA H + +LYTKR+FRCDCGNS F     C LWEEKDD+NI+N Y+HNF G++C C   Y + +
Sbjct:    8 TLDEIVSSETSESAVVYGAIEDEEEKCTFPKGYLKRQAVFACKTCSELTGKRAGVCYECSIHCHATHEIVELYTKRHFRCDCGNSKFKGAAVCNLWEEKDDVNIENSYDHNFDGVFCTCLRPYPDPE 134

HSP 2 Score: 103.219 bits (256), Expect = 4.529e-20
Identity = 73/253 (28.85%), Postives = 113/253 (44.66%), Query Frame = 2 
Query:  884 IYAYNSHLIQDTEEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALYNRASVNKVLGKYIAADGNCNL-----------EAARAALEQLGNNCEEPGSLS-----------------GNNG-----GAFWPSDWR-ESLCRCASCQQLMKRDETGFLHNANDTIAYYYTNDQEKF-------NDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNNGGPDKVVTTEDVHNFFDKIKR 1519
            +  Y    I+   EM QC +CEDW+HL+HL    SD QP + FEE VC  C++R   L L+    V            +C+L           + + AA  +    C  P  LS                   NG       FW +DWR ++LC C SC++++K    GFL +  D+I +Y    +++        ++   E ++ +P   AI++A GI  F+  L +FL       VVT E+V  F + +K+
Sbjct:  127 LRPYPDPEIKGNSEMYQCSVCEDWFHLQHLNMP-SDFQPSDDFEELVCSSCVKRFPLLWLFYYCHVQSGNADNANQSRDCSLAKKPRIDDGVDQMSTAASVESTETCRIPHVLSVCGVENVDPPTADMRRLTVNGLPFPSPIFWCNDWRTDTLCTCDSCEKMLKSLGIGFLLDPEDSIVHYMEVGRQRVAELHARRDNLISEALAELPRPAAIEVARGINRFREALTDFLTRPREQNVVTEEEVKEFCEDLKK 378
[Close]
BLAST of UBR-type domain-containing protein vs. TrEMBL
Match: A0A5K3G4N2 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 7.754e-34
Identity = 62/116 (53.45%), Postives = 85/116 (73.28%), Query Frame = 1 
Query:   73 DYETRNLAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDES 420
            D E   + G D + +C TFP+GY  RQALY C TC E++GK+AG+C+ CS+ CH  H + +LYTKR+FRCDCGNSNF    +C+LWEEKDD+N++NKY+  F G++CVC+  Y + 
Sbjct:   18 DEEVIIMGGADGEPAC-TFPRGYLKRQALYVCKTCYEVTGKRAGVCYECSLQCHCDHEVVELYTKRHFRCDCGNSNFKGASECKLWEEKDDVNVENKYDQTFDGVFCVCSRPYPDP 132

HSP 2 Score: 85.5001 bits (210), Expect = 3.878e-14
Identity = 63/241 (26.14%), Postives = 101/241 (41.91%), Query Frame = 2 
Query:  923 EMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALY------------------------NRASVNKVLGKYIAADGNCNLEAARAALEQLGNNCEEPGSLSGNN---------GGAFWPSDWRES-LCRCASCQQLMKRDETGFLHNANDTIAYYYTNDQEKFNDEFKEQ-------MSTMPHAVAIKLADGIAYFKRELIEF-LNNGGPDKVVTTEDVHNFFDKIKR 1519
            EM QC ICEDW+H  HL     D  P + +EE  C  C++R   L L                          R   +    +Y +++ N  +      L   G +   P   +               FWP +WR S LC C SC+ ++K  +  F+ +  D+IA+Y    +++  +   E+       +S +PH+ AI +A GI   +  + EF L       V+T E+V  F D++K+
Sbjct:  139 EMFQCGICEDWFHTHHLGLP-PDFLPNDDYEELTCLNCIKRLPLLWLLYYSLMHSQEKESCVELDEEPSSKKPRRDSDICPPEYPSSNSNGEICRMPQVLANCGVDTATPSPATLQKLVVRGFSFPSPIFWPKNWRTSALCACESCRNMLKTLDIEFILDPEDSIAHYMQVGKQRVQEIQSERESAISAALSELPHSAAINIARGITKLESAIAEFLLREREKGHVITEEEVKAFCDELKK 378
[Close]
BLAST of UBR-type domain-containing protein vs. TrEMBL
Match: A0A0R3WII4 (UBR-type domain-containing protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS410 PE=4 SV=1)

HSP 1 Score: 140.584 bits (353), Expect = 2.001e-33
Identity = 64/132 (48.48%), Postives = 90/132 (68.18%), Query Frame = 1 
Query:   40 EEDTISFQEIYDYETRNLA----GCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESK 423
            +++  +  E+   ET   A      ++++  CTFPKGY  RQA++ C TC EI+GK+AG+C+ CS+HCHA H + +LYTKR+FRCDCGNS F     C LWEEKDD+NI+NKY+H F G++C C   Y + +
Sbjct:    3 DDEYFTLDELVSSETSESAVVYGAIEDEEEKCTFPKGYLKRQAVFACKTCYEITGKRAGVCYECSMHCHAAHEIIELYTKRHFRCDCGNSKFKGAGVCSLWEEKDDVNIENKYDHTFDGVFCTCLRPYPDPE 134

HSP 2 Score: 83.1889 bits (204), Expect = 1.649e-13
Identity = 65/244 (26.64%), Postives = 103/244 (42.21%), Query Frame = 2 
Query:  884 IYAYNSHLIQDTEEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALYNRASVNKVLGKYIAADGNCNLEAARAALEQLGNNCEEPGSLSGN--------------------------NG-----GAFWPSDWR-ESLCRCASCQQLMKRDETGFLHNANDTIAYYYTNDQEKFNDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNNGGPDKVVTTEDVHNFFDKIKR 1519
            +  Y    I++ EEM QC ICEDW+HL+HL     D QP + FEE VC  C++R  +L L+    +     +      +C+    +A  + + N  E PGS                              NG       FW +DWR ++LC C SC+++++     FL +  D++ +Y    +++  +    + S             I  FK  L  FL       VVT E+V  F + +K+
Sbjct:  127 LRPYPDPEIKENEEMYQCSICEDWFHLQHLNMP-FDFQPNDDFEELVCPNCVKRFPFLWLFYYCQMQSRNAENANHFSDCS-SPKKAKPDDIINQPEAPGSTEACRVPYVLSVCGVEKLDPPPADMVRLTVNGFPFPSPIFWCNDWRTDTLCDCNSCEKMLENMGLEFLLDPEDSVVHYMAVGRQRVAELHARRES-------------ICRFKEALTNFLTKPREQNVVTEEEVKEFCEDLKK 355
[Close]
BLAST of UBR-type domain-containing protein vs. TrEMBL
Match: A0A087W1E8 (E3 ubiquitin protein ligase UBR7 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000218200 PE=4 SV=1)

HSP 1 Score: 140.969 bits (354), Expect = 2.287e-33
Identity = 64/127 (50.39%), Postives = 87/127 (68.50%), Query Frame = 1 
Query:   55 SFQEIYDYETRNLA----GCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESK 423
            +  EI   ET   A      ++D+  CTFPKGY  RQA++ C TC E++GK+AG+C+ CS++CHA H + +LYTKR+FRCDCGNS F     C LWEEKDD+N +NKY+HNF G++C C   Y + +
Sbjct:    8 TLDEIVSSETSESAVVYGAIEDDEEKCTFPKGYLKRQAVFACKTCYELTGKRAGVCYECSMNCHAAHEIVELYTKRHFRCDCGNSKFKGAAVCNLWEEKDDVNTENKYDHNFDGVFCTCLRPYPDPE 134

HSP 2 Score: 102.834 bits (255), Expect = 4.771e-20
Identity = 71/246 (28.86%), Postives = 116/246 (47.15%), Query Frame = 2 
Query:  884 IYAYNSHLIQDTEEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALY-----NRASVNKVLGKYIAADGNCN----------LEAAR-------AALEQLGNNCEEPGSLSGNN----GGAFWPSDWR-ESLCRCASCQQLMKRDETGFLHNANDTIAYYY-------TNDQEKFNDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNNGGPDKVVTTEDVHNFFDKIKR 1519
            +  Y    ++   EM QC ICEDW+HL+HL     D +P + FEE VC  C++R   L L+        + +  L K    D + N           EA R         +++L     + G L+ N        FW +DWR ++LC C SC++++K  + GFL +  D++ +Y           Q +  +   E ++ +PH  A+++A GI+ F+  L +FL       VVT E+V  F + +K+
Sbjct:  127 LRPYPDPELEGNTEMYQCSICEDWFHLQHLNMP-LDFRPNDDFEELVCLNCVKRFPLLWLFYYCQMQPKNADCSLPKKPRIDDSVNQLNTSASVKSTEACRIPHVLSVCGVKKLNPPTADMGRLTVNGLSFPSPIFWCNDWRTDTLCTCDSCKKMLKSLDIGFLLDPEDSVVHYMEVGRQRVAQLQARRENLISEALAELPHPAAVEVARGISRFREALTDFLTKPREKNVVTEEEVKEFCEDLKK 371
[Close]
BLAST of UBR-type domain-containing protein vs. TrEMBL
Match: U6JE40 (E3 ubiquitin protein ligase UBR7 OS=Echinococcus granulosus OX=6210 GN=EGR_08657 PE=4 SV=1)

HSP 1 Score: 140.584 bits (353), Expect = 3.149e-33
Identity = 64/127 (50.39%), Postives = 87/127 (68.50%), Query Frame = 1 
Query:   55 SFQEIYDYETRNLA----GCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESK 423
            +  EI   ET   A      ++D+  CTFPKGY  RQA++ C TC E++GK+AG+C+ CS++CHA H + +LYTKR+FRCDCGNS F     C LWEEKDD+N +NKY+HNF G++C C   Y + +
Sbjct:    8 TLDEIVSSETSESAVVYGAIEDDEEKCTFPKGYLKRQAVFACKTCYELTGKRAGVCYECSMNCHAAHEIVELYTKRHFRCDCGNSKFKGASVCNLWEEKDDVNTENKYDHNFDGVFCTCLRPYPDPE 134

HSP 2 Score: 100.908 bits (250), Expect = 2.518e-19
Identity = 67/246 (27.24%), Postives = 114/246 (46.34%), Query Frame = 2 
Query:  884 IYAYNSHLIQDTEEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALY---------------NRASVNKVLGKYIAADGNCNLEAAR-------AALEQLGNNCEEPGSLSGNN----GGAFWPSDWR-ESLCRCASCQQLMKRDETGFLHNANDTIAYYY-------TNDQEKFNDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNNGGPDKVVTTEDVHNFFDKIKR 1519
            +  Y    ++   EM QC ICEDW+HL+HL     D +P + FEE VC  C++R   L L+                +  ++  + +   +    + EA R         + +L     + G L+ N        FW +DWR ++LC C SC++++K    GFL +  D++ +Y           Q +  +   E ++ +PH  A+++A GI+ F+  L +FL       VVT E+V  F + +K+
Sbjct:  127 LRPYPDPELEGNTEMYQCSICEDWFHLQHLNMP-LDFRPNDDFEELVCLNCVKRFPLLWLFYYCQMQPENADCSLPKKPRIDDSVDQLNTSASVKSTEACRIPHVLSVCGVRKLNPPTADMGRLTVNGFSFPSPIFWCNDWRTDTLCTCDSCKKMLKSLGIGFLLDPEDSVVHYMEVGRQRVAQLQARRENLISEALAELPHPAAVEVARGISRFREALTDFLTKPREKNVVTEEEVKEFCEDLKK 371
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Cavefish
Match: ubr7 (putative E3 ubiquitin-protein ligase UBR7 [Source:NCBI gene;Acc:103040793])

HSP 1 Score: 122.479 bits (306), Expect = 4.704e-30
Identity = 65/142 (45.77%), Postives = 88/142 (61.97%), Query Frame = 1 
Query:   19 MAESENLEEDTISFQEIYDY-------ETRNLAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESK 423
            MA +E  EE T+S  ++ +         +  L G D++   C++P+GY  RQALY C TC    G+ AGIC  CS  CH GH L +LYTKRNFRCDCGN  F +  +C+L+ EK+ +N  NKY+HNF GLYC C+  Y + +
Sbjct:    1 MAANEGGEEATVSLVDVLEEDEELEQEASAVLGGSDSEK--CSYPEGYVKRQALYACNTCTPKGGEPAGICLACSYKCHEGHELFELYTKRNFRCDCGNDKFGE-LECKLFTEKEKVNSGNKYSHNFFGLYCTCDRPYPDPE 139

HSP 2 Score: 75.8702 bits (185), Expect = 2.062e-14
Identity = 63/258 (24.42%), Postives = 102/258 (39.53%), Query Frame = 2 
Query:  917 TEEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALY---------------------------------NRASVNKVLGKYIAADGNCNLEAARAALEQLGNNCEEPGSLSG--------------NNGGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYY----YTNDQ---EKFNDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNN-GGPDKVVTTEDVHNFFDKIKRRR 1525
            ++EMIQC++CEDW H +HL     +   L+   E +C+ C+ +  +L  Y                                    S + V  K +  +G       +  L++L N+  E GS SG                G  FWP+ WR  LC C  C+ +       FL +  DT+  Y     T +Q    +  D     ++T+     +++       K EL ++L       KVVT ED+ NFF++ + R+
Sbjct:  143 SDEMIQCIVCEDWLHGRHLGCVVPECVELQ---EMICESCMNKSPFLWTYAAHIAVPPVLKVCKAEEAEKVDVDHVEEESKPEKEDSKSPVDDKQVEMNGT---AGCKRKLQELENSSAE-GSCSGCRLAEMKTSGQSRAQQGAVFWPAAWRAKLCSCTHCKNVFTDAGVAFLLDETDTVLAYENKGKTTEQAGGAEGRDPLMSALNTLNRVQQLEIIHEYNDMKTELKDYLQRFAAEGKVVTPEDIRNFFEQQQSRK 393
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000015002.2 (putative E3 ubiquitin-protein ligase UBR7 [Source:NCBI gene;Acc:103039744])

HSP 1 Score: 110.923 bits (276), Expect = 4.740e-26
Identity = 58/127 (45.67%), Postives = 77/127 (60.63%), Query Frame = 1 
Query:   49 TISFQEIYDYETRN----LAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDE 417
             +S  ++ D E R     LAG D D   C++ +GY  RQA++ C TCR    +  G+C  C+ HCH GH + +LYTKRNF CDCGN NF   F+C+L  +KD  N KN YNHN+ G YC C+  Y +
Sbjct:   10 AVSLVDVEDEELREALAVLAGSDPDQ--CSYQQGYMKRQAVFACNTCRTEGMEPTGVCLACANHCHDGHDIFELYTKRNFCCDCGNKNF-GTFECKLSPKKDSQNTKNVYNHNYFGRYCSCDRPYPD 133

HSP 2 Score: 83.1889 bits (204), Expect = 1.039e-16
Identity = 76/285 (26.67%), Postives = 103/285 (36.14%), Query Frame = 2 
Query:  851 YIMRYSVSVVPIYAYNSHLIQDTEEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALY-----------------NRASVNKVLGKYIAADGN--------------------------------------CNLEAARAALEQLGNNCEEPGSLSGNNGGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYYYTNDQEKFNDEFKEQ-MSTMPHAVAIKLADGIAYFKRELIEFLNN-GGPDKVVTTEDVHNFFDKI---KRRR 1525
            Y  RY     P   Y     Q  EEMIQC+ICEDWYHLKHL  +  DS   E   E VC+ C+ +  +L  Y                    +V K    Y   DG                                       C  EAA   L+ L       G +    G  FWP  WR  LC C  C++        FL + +DT+  Y    +    ++      S++     +++       K EL  FL +     K VT E +H FF+++   KRRR
Sbjct:  120 YFGRYCSCDRP---YPDEDDQVGEEMIQCIICEDWYHLKHLGCAAVDS---EELLEMVCESCMNKAPFLWTYAAYFATPPVTSKENEDVTTPNVEKETSSYPCRDGGHAEPSTSQGCIKNPTLPNGDRTESQKRTREEMERHSSACQSEAALCKLKNLKTK----GLVRPRVGSVFWPYCWRSKLCTCTDCKRAYVEAGVQFLLDESDTVLAYENKGKSLLREDLLTSCFSSLDRVQQLEIIYQFNDMKDELNAFLRDLADQGKEVTPEAIHAFFEELQAKKRRR 394
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ubr7 (ubiquitin protein ligase E3 component n-recognin 7 [Source:ZFIN;Acc:ZDB-GENE-030131-1535])

HSP 1 Score: 55.8398 bits (133), Expect = 7.246e-9
Identity = 31/93 (33.33%), Postives = 45/93 (48.39%), Query Frame = 2 
Query:  911 QDTEEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALYNRASVNKVLGKYIAADGNCNLEAARAALEQLGNNCEEPGSL 1189
            +  +EMIQC+ICEDW H +HL     +S     + E VC  C+ RC +L  Y   S    + +       C+   AR  ++ +  N E  GSL
Sbjct:   49 KTPDEMIQCIICEDWLHGRHLGVEAPESV---EYHEMVCGGCMARCSFLWAYAVPSAGDTVARVARPCRRCSGTGARKVVKLV--NEEHEGSL 136

HSP 2 Score: 53.5286 bits (127), Expect = 4.219e-8
Identity = 24/47 (51.06%), Postives = 29/47 (61.70%), Query Frame = 1 
Query:  280 CDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDES 420
            CDCGN+ FP    C+L  +K+  N  NKYNHNF GLYC C   Y + 
Sbjct:    1 CDCGNARFP-VVACKLLPDKEASNPGNKYNHNFFGLYCTCKKPYPDP 46
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Nematostella
Match: EDO38158 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDR6])

HSP 1 Score: 126.331 bits (316), Expect = 9.675e-32
Identity = 64/138 (46.38%), Postives = 85/138 (61.59%), Query Frame = 1 
Query:   25 ESENLEEDTISFQEIYDY-----ETRNLAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESK 423
            E  NL ++ +S  ++        E  N    D+DD  CT+ KGY  RQALY C TC   S + AG+C  CS+ CH GH L +LYTKRNFRCDCGNS F + F C+L+ +KD +N  N YN NF+G+YC C+  Y + +
Sbjct:    2 EGSNLTDEVVSMVDVLQEDNELEEEANAVFGDSDDQQCTYEKGYVGRQALYACSTCSCPSSEPAGLCLACSLTCHDGHELYELYTKRNFRCDCGNSKF-EGFNCKLFPDKDAVNKSNMYNQNFTGVYCTCHRPYPDPE 138

HSP 2 Score: 55.0694 bits (131), Expect = 3.417e-8
Identity = 31/115 (26.96%), Postives = 49/115 (42.61%), Query Frame = 2 
Query: 1202 GGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYYYTNDQEKFNDEFKEQMSTMPHAVAIKLADGIAYF---KRELIEFLNN-GGPDKVVTTEDVHNFFDKIKRRRLEK 1534
            G +FW   WR  LC C  C+ L       FL +  DT+  Y    Q      ++  M  +     I   + +  +   K EL +FL       KVV  ED+  FF+ ++ R+ ++
Sbjct:  290 GASFWNVGWRAQLCTCTKCKTLYNTLGVSFLTSEQDTLVAYEARGQSARQSAYESGMQALGGMGRINQVEALHEYNNMKDELTDFLREFATQGKVVKPEDIQGFFESMQARKRQR 404

HSP 3 Score: 52.373 bits (124), Expect = 2.526e-7
Identity = 22/53 (41.51%), Postives = 33/53 (62.26%), Query Frame = 2 
Query:  920 EEMIQCVICEDWYHLKHLA----ASGSDSQPLEHFEEFVCKLCLERCEYLALY 1066
            +EMIQC++CEDWYH +HL     A+G        ++E +C  C++RC +L  Y
Sbjct:  143 DEMIQCIVCEDWYHSRHLGCLPPANGD-------YQEMICDSCMDRCTFLQAY 188
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Medaka
Match: ubr7 (putative E3 ubiquitin-protein ligase UBR7 [Source:NCBI gene;Acc:101174971])

HSP 1 Score: 125.946 bits (315), Expect = 1.693e-31
Identity = 62/109 (56.88%), Postives = 73/109 (66.97%), Query Frame = 1 
Query:   91 LAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDE 417
            LAG D+D   C++P GY  RQALY C TC    G+ AG+C  CS  CH GH L +LYTKRNFRCDCGN  F D  +C+L  EKDDIN  NKY+HNF G+YC C   Y +
Sbjct:   27 LAGSDSDH--CSYPLGYVKRQALYACNTCTPKGGEAAGVCLACSYKCHEGHELFELYTKRNFRCDCGNRKFSD-LQCKLQPEKDDINSLNKYSHNFFGVYCTCRRPYPD 132

HSP 2 Score: 93.5893 bits (231), Expect = 2.371e-20
Identity = 64/231 (27.71%), Postives = 104/231 (45.02%), Query Frame = 2 
Query:  920 EEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALY--------------NRASVNKVLGKYIAADGNCNLEAARAALEQLGNNC-----EEPGSLSGNNGGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYY----YTNDQEK-FNDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNN-GGPDKVVTTEDVHNFFDK--IKRRRLE 1531
            +EMIQCV+CEDW H +HL     D   L+   E +C+ C++R   L +Y                    ++  K    + +    + + + E+   +C     +  G     +G  FWPS WR  LC CASCQ ++      FL +  DT+  Y     T ++E+   D     +  +     +++  G    K +L +FL       KVVT+ED+  FF++   KRRR++
Sbjct:  139 DEMIQCVVCEDWLHSRHLGCVVPDCVELQ---EMICEACMKRSPVLWVYAAHLAAAGPEEPKEEGPGAEEITAKSENHEKDVTEPSCKRSHEEAEPSCRLKELQAGGQKRVQSGAVFWPSGWRSKLCSCASCQLMLSEAGLSFLLDEADTVLEYENKGKTREREQPGTDPLMSALDNLSRVQQLEIIHGYNDMKTDLKDFLQRFAAEGKVVTSEDIRQFFEQQSSKRRRMD 366
[Close]
BLAST of UBR-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000020014.2 (ubiquitin protein ligase E3 component n-recognin 7 (putative) [Source:NCBI gene;Acc:101157579])

HSP 1 Score: 114.005 bits (284), Expect = 5.760e-27
Identity = 56/110 (50.91%), Postives = 75/110 (68.18%), Query Frame = 1 
Query:   91 LAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDES 420
            LAG D ++  C++ +GY  RQA++ C TC   + + AGIC  C+  CH GH + +LYTKR+FRCDCGN  F D F+CQL   KD+ N KN+YNHNFSG YC C+  Y ++
Sbjct:   63 LAGSDPEN--CSYSRGYVKRQAVFACNTCTPDATEPAGICLACANKCHDGHDIFELYTKRHFRCDCGNGKFGD-FQCQLNPAKDERNDKNRYNHNFSGCYCTCDRPYPDT 169

HSP 2 Score: 87.0409 bits (214), Expect = 5.954e-18
Identity = 69/256 (26.95%), Postives = 108/256 (42.19%), Query Frame = 2 
Query:  911 QDTEEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALY---------------------NRASVNKVLGKYIAADGNCNLEAARAALEQLGNNCEE------------PG-----SLSG----NNGGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYYYTNDQEKFNDEFKEQ-----MSTMPHAVAIKLADGIAYFKRELIEFLNNGGPD-KVVTTEDVHNFFDKIKRRRLEK 1534
            QD +EMIQCVICEDW+H KHL  +  +    E  +E VC+ C+ +  +L  Y                           K   K    +G+ + + +R A   +G++  +            PG      L G      G  FWP  WR  LC C +C++     E  FL + +DTI  Y   ++   ++ F +      +S+M     +++  GI      L EFL     + K VT E VH FF +++ R+  +
Sbjct:  172 QDDDEMIQCVICEDWFHSKHLGCTVVEP---EELQEMVCETCMNKAPFLWTYAAHFAEPPFIKISHSNKEEDVEVEVEEKSPEKRPRNEGSTSSDESRKAEAGIGSSPRKRNHPETSKVNTTPGECRLKKLQGLERPRLGAVFWPYSWRSELCTCTNCKKAYVAAEVQFLMDQSDTILAY---EKRGLDEPFGQHPLMALLSSMDRVQQLEVLYGINELTSSLNEFLEQCVSERKTVTAEAVHEFFAELRARKKRR 421
[Close]
BLAST of UBR-type domain-containing protein vs. Planmine SMEST
Match: SMESG000037081.1 (SMESG000037081.1)

HSP 1 Score: 432.95 bits (1112), Expect = 1.419e-149
Identity = 206/209 (98.56%), Postives = 207/209 (99.04%), Query Frame = 2 
Query:  914 DTEEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALYNRASVNKVLGKYIAADGNCNLEAARAALEQLGNNCEEPGSLSGNNGGAFWPSDWRESLCRCASCQQLMKRDETGFLHNANDTIAYYYTNDQEKFNDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNNGGPDKVVTTEDVHNFFDKIKRRRLEKFE 1540
            DTEEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALYN ASVNKVLGKY AADGNCNLEAARAALEQLGNNCEEPGSLSGNNGGAFWPSDWRESLCRCASCQQLM+RDETGFLHNANDTIAYYYTNDQEKFNDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNNGGPDKVVTTEDVHNFFDKIKRRRLEKFE
Sbjct:  136 DTEEMIQCVICEDWYHLKHLAASGSDSQPLEHFEEFVCKLCLERCEYLALYNLASVNKVLGKYTAADGNCNLEAARAALEQLGNNCEEPGSLSGNNGGAFWPSDWRESLCRCASCQQLMERDETGFLHNANDTIAYYYTNDQEKFNDEFKEQMSTMPHAVAIKLADGIAYFKRELIEFLNNGGPDKVVTTEDVHNFFDKIKRRRLEKFE 344

HSP 2 Score: 284.648 bits (727), Expect = 1.179e-91
Identity = 134/134 (100.00%), Postives = 134/134 (100.00%), Query Frame = 1 
Query:   19 MAESENLEEDTISFQEIYDYETRNLAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDES 420
            MAESENLEEDTISFQEIYDYETRNLAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDES
Sbjct:    1 MAESENLEEDTISFQEIYDYETRNLAGCDNDDSCCTFPKGYAYRQALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSNFPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDES 134
The following BLAST results are available for this feature:
BLAST of UBR-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
UBR71.520e-2551.40ubiquitin protein ligase E3 component n-recognin 7... [more]
UBR71.520e-2551.40ubiquitin protein ligase E3 component n-recognin 7... [more]
AL110118.22.527e-2553.13novel protein[more]
AL110118.42.527e-2553.13novel protein[more]
UBR71.640e-1840.54ubiquitin protein ligase E3 component n-recognin 7... [more]
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BLAST of UBR-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
T22C1.11.262e-2441.09pep chromosome:WBcel235:I:7936264:7937865:1 gene:W... [more]
T22C1.11.262e-2441.09pep chromosome:WBcel235:I:7936223:7938328:1 gene:W... [more]
T22C1.11.262e-2441.09pep chromosome:WBcel235:I:7936264:7938328:1 gene:W... [more]
ubr-47.063e-632.20UBR E3 ubiquitin ligase homolog [Source:UniProtKB... [more]
ubr-47.123e-632.20UBR E3 ubiquitin ligase homolog [Source:UniProtKB... [more]
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BLAST of UBR-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG151416.039e-2241.67gene:FBgn0032635 transcript:FBtr0080979[more]
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BLAST of UBR-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ubr73.045e-2952.25ubiquitin protein ligase E3 component n-recognin 7... [more]
CABZ01066926.13.371e-1426.55putative E3 ubiquitin-protein ligase UBR7 [Source:... [more]
ubr72.426e-627.05ubiquitin protein ligase E3 component n-recognin 7... [more]
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BLAST of UBR-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pbx17.840e-2742.45pre-B-cell leukemia homeobox 1 [Source:Xenbase;Acc... [more]
pbx18.325e-2742.45pre-B-cell leukemia homeobox 1 [Source:Xenbase;Acc... [more]
pbx19.298e-2742.45pre-B-cell leukemia homeobox 1 [Source:Xenbase;Acc... [more]
pbx11.059e-2642.45pre-B-cell leukemia homeobox 1 [Source:Xenbase;Acc... [more]
pbx11.215e-2650.45pre-B-cell leukemia homeobox 1 [Source:Xenbase;Acc... [more]
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BLAST of UBR-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Ubr71.333e-2550.45ubiquitin protein ligase E3 component n-recognin 7... [more]
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BLAST of UBR-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|Q8N806|UBR7_HUMAN7.301e-2551.40Putative E3 ubiquitin-protein ligase UBR7 OS=Homo ... [more]
sp|Q8BU04|UBR7_MOUSE9.325e-2550.45Putative E3 ubiquitin-protein ligase UBR7 OS=Mus m... [more]
sp|Q09329|MLO2_SCHPO5.380e-2044.90Protein mlo2 OS=Schizosaccharomyces pombe (strain ... [more]
sp|Q54DV0|UBR7_DICDI5.653e-1434.44Putative E3 ubiquitin-protein ligase ubr7 OS=Dicty... [more]
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BLAST of UBR-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3W7I54.896e-3450.39UBR-type domain-containing protein OS=Taenia asiat... [more]
A0A5K3G4N27.754e-3453.45Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A0R3WII42.001e-3348.48UBR-type domain-containing protein OS=Hydatigena t... [more]
A0A087W1E82.287e-3350.39E3 ubiquitin protein ligase UBR7 OS=Echinococcus m... [more]
U6JE403.149e-3350.39E3 ubiquitin protein ligase UBR7 OS=Echinococcus g... [more]
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BLAST of UBR-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ubr74.704e-3045.77putative E3 ubiquitin-protein ligase UBR7 [Source:... [more]
ENSAMXT00000015002.24.740e-2645.67putative E3 ubiquitin-protein ligase UBR7 [Source:... [more]
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BLAST of UBR-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ubr77.246e-933.33ubiquitin protein ligase E3 component n-recognin 7... [more]
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BLAST of UBR-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of UBR-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO381589.675e-3246.38Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of UBR-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ubr71.693e-3156.88putative E3 ubiquitin-protein ligase UBR7 [Source:... [more]
ENSORLT00000020014.25.760e-2750.91ubiquitin protein ligase E3 component n-recognin 7... [more]
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BLAST of UBR-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000037081.11.419e-14998.56SMESG000037081.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010763 ID=SMED30010763|Name=UBR-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1606bp
CATCTTATTTCTAATATTATGGCTGAATCTGAAAATCTTGAAGAAGATAC
TATTTCATTTCAAGAAATTTATGATTACGAAACTAGAAATCTGGCCGGAT
GTGACAATGATGATTCCTGTTGTACCTTTCCAAAAGGATATGCGTATCGG
CAGGCATTATATCACTGCTTGACATGTAGGGAAATTAGTGGCAAACAAGC
AGGAATTTGTTTTCCTTGTTCTGTTCATTGTCACGCTGGACATGTTCTTG
AAGATCTTTATACAAAGAGAAATTTTCGCTGTGATTGTGGAAATTCTAAT
TTTCCCGACAACTTTAAATGTCAGTTATGGGAGGAAAAAGATGATATCAA
CATAAAAAATAAATACAATCATAACTTTTCTGGACTCTATTGTGTTTGCA
ATTCAGAATATGATGAAAGCAAAGTGAGTTTATTTACATTAACCTTATCT
GTTTCTACAAGTTAATTTTAATTTCTTTTTTACGTCATGAATTTATATTT
GAAATATCAATTTAAAAAACAACTGCCTGTTTTTGGTCCCCTAAGGCATT
GCAGCGTAAATCATTACACAGAGCAATCTATATAATATTTACAATACAAT
ATTTACGGTTGGGATTCACCGGCAATCAGCTTCCATGCTCATTTTAACCA
ATGCAGCACATAGCTGCTTGCTAGTCCTTAATATGCTCTACTTTATGAGC
TTTTCCAAACCACTTTCTGTCCGCCTTATTGTTCGATTCGGATTTCAGTA
AGCATTAGCTGGGACATCCTCTATTCCACACCACTGTAGCTCTCATGGAT
TCTCATCAGACACAATAATGGTCCACTTCATCTTCATTCATTCACTGCCA
TATATTATGCGATACTCTGTATCCGTTGTCCCCATATATGCGTATAACTC
TCATCTCATTCAGGACACCGAGGAAATGATTCAATGCGTCATCTGTGAGG
ATTGGTATCATCTAAAGCATCTCGCAGCATCGGGCTCTGACAGCCAGCCA
TTGGAGCATTTCGAGGAATTCGTATGTAAATTGTGCCTGGAAAGGTGTGA
GTATCTCGCCTTGTATAACCGAGCAAGTGTTAACAAAGTGCTTGGCAAAT
ACATAGCAGCTGATGGAAACTGCAACTTGGAAGCAGCAAGGGCTGCATTG
GAGCAATTGGGGAATAATTGTGAGGAACCCGGATCGCTGTCTGGCAATAA
CGGCGGTGCGTTCTGGCCGAGTGATTGGAGGGAGAGTTTGTGTCGGTGTG
CCAGCTGCCAGCAACTGATGAAGCGAGATGAAACTGGATTCCTGCACAAT
GCCAATGATACAATCGCATATTACTACACCAATGACCAGGAGAAATTCAA
CGATGAGTTCAAGGAGCAGATGTCGACGATGCCGCATGCTGTAGCTATCA
AGTTGGCTGACGGAATCGCATATTTCAAGCGGGAATTGATAGAATTCTTG
AATAATGGTGGTCCGGACAAGGTGGTCACCACAGAAGACGTTCACAACTT
CTTTGACAAGATCAAGCGCAGGAGACTCGAGAAATTCGAATGAATTCTAC
GCCGGTTTCAATTTAATTTCAGCAATTTATGTAGTATTGTATAATAAATA
CTGTGT
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protein sequence of SMED30010763-orf-1

>SMED30010763-orf-1 ID=SMED30010763-orf-1|Name=SMED30010763-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=155bp
HLISNIMAESENLEEDTISFQEIYDYETRNLAGCDNDDSCCTFPKGYAYR
QALYHCLTCREISGKQAGICFPCSVHCHAGHVLEDLYTKRNFRCDCGNSN
FPDNFKCQLWEEKDDINIKNKYNHNFSGLYCVCNSEYDESKVSLFTLTLS
VSTS*
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protein sequence of SMED30010763-orf-2

>SMED30010763-orf-2 ID=SMED30010763-orf-2|Name=SMED30010763-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=242bp
MVHFIFIHSLPYIMRYSVSVVPIYAYNSHLIQDTEEMIQCVICEDWYHLK
HLAASGSDSQPLEHFEEFVCKLCLERCEYLALYNRASVNKVLGKYIAADG
NCNLEAARAALEQLGNNCEEPGSLSGNNGGAFWPSDWRESLCRCASCQQL
MKRDETGFLHNANDTIAYYYTNDQEKFNDEFKEQMSTMPHAVAIKLADGI
AYFKRELIEFLNNGGPDKVVTTEDVHNFFDKIKRRRLEKFE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0016567protein ubiquitination
Vocabulary: molecular function
TermDefinition
GO:0046872metal ion binding
GO:0061630ubiquitin protein ligase activity
GO:0008270zinc ion binding
GO:0016874ligase activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR040204UBR7
IPR003126Znf_UBR
IPR013083Znf_RING/FYVE/PHD
IPR011011Znf_FYVE_PHD
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 26..76
e-value: 1.7E-8
score: 35.9
IPR040204E3 ubiquitin-protein ligase UBR7PANTHERPTHR13513E3 UBIQUITIN-PROTEIN LIGASE UBR7coord: 26..236
NoneNo IPR availableCDDcd15542PHD_UBR7coord: 35..73
e-value: 2.36542E-13
score: 60.8443
IPR011011Zinc finger, FYVE/PHD-typeSUPERFAMILYSSF57903FYVE/PHD zinc fingercoord: 33..83