Endoplasmic reticulum chaperone BiP

Overview
NameEndoplasmic reticulum chaperone BiP
Smed IDSMED30010742
Length (bp)881
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Endoplasmic reticulum chaperone BiP (SMED30010742) t-SNE clustered cells

Violin plots show distribution of expression levels for Endoplasmic reticulum chaperone BiP (SMED30010742) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30010742

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
prepharyngeal regionSMED30010742h1SMcG0011102 SmedASXL_019761SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
prepharyngeal regionSMED30010742h1SMcG0011102 SmedASXL_009247SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
neoblastSMED30010742h1SMcG0011102 SMED_27863_V2_1GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30010742h1SMcG0011102 SMED_27863_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30010742h1SMcG0011102 SMED_27864_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30010742h1SMcG0011102 SMED_27864_V2_1GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Human
Match: HSPA5 (heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238])

HSP 1 Score: 412.92 bits (1060), Expect = 8.533e-141
Identity = 200/248 (80.65%), Postives = 223/248 (89.92%), Query Frame = 3 
Query:  138 DSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGE-ENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            + E  K+D GTV+GIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLTSNPENT+FD KR IGR ++D +V+QDIK  PF V+ K  KP++QV +G  + + FAPEEISAMVL KMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDK+EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+++F
Sbjct:   19 EEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 266
[Close]
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Human
Match: HSPA8 (heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241])

HSP 1 Score: 361.303 bits (926), Expect = 1.057e-122
Identity = 173/239 (72.38%), Postives = 207/239 (86.61%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP NT+FD KR IGR FDD  V+ D+K++PF+V+N   +P VQV+   E + F PEE+S+MVL KMKEIAE+YLGK VT+AVVTVPAYFND+QRQATKDAGTI+GLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGG DFD R++++F
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
[Close]
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Human
Match: HSPA8 (heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241])

HSP 1 Score: 362.073 bits (928), Expect = 4.797e-121
Identity = 173/239 (72.38%), Postives = 207/239 (86.61%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP NT+FD KR IGR FDD  V+ D+K++PF+V+N   +P VQV+   E + F PEE+S+MVL KMKEIAE+YLGK VT+AVVTVPAYFND+QRQATKDAGTI+GLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGG DFD R++++F
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
[Close]
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Human
Match: HSPA8 (heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241])

HSP 1 Score: 362.073 bits (928), Expect = 4.797e-121
Identity = 173/239 (72.38%), Postives = 207/239 (86.61%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP NT+FD KR IGR FDD  V+ D+K++PF+V+N   +P VQV+   E + F PEE+S+MVL KMKEIAE+YLGK VT+AVVTVPAYFND+QRQATKDAGTI+GLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGG DFD R++++F
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
[Close]
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Human
Match: HSPA8 (heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241])

HSP 1 Score: 362.073 bits (928), Expect = 4.797e-121
Identity = 173/239 (72.38%), Postives = 207/239 (86.61%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP NT+FD KR IGR FDD  V+ D+K++PF+V+N   +P VQV+   E + F PEE+S+MVL KMKEIAE+YLGK VT+AVVTVPAYFND+QRQATKDAGTI+GLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGG DFD R++++F
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
[Close]
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Celegans
Match: hsp-3 (Heat shock 70 kDa protein C [Source:UniProtKB/Swiss-Prot;Acc:P27420])

HSP 1 Score: 404.06 bits (1037), Expect = 9.787e-138
Identity = 195/240 (81.25%), Postives = 222/240 (92.50%), Query Frame = 3 
Query:  162 YGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFT-QESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            YGT+IGIDLGTTYSCVGV+K+GRVEIIANDQGNRITPSYVAF+  + +RLIGDAAKNQLT NPENTIFD KR IGR ++D+TV+ DIK++PF VI+K+NKP V+VKVG +N+ F PEE+SAMVL KMKEIAESYLGK V +AVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDKK+GE+NILVFDLGGGTFDVS+LTIDNGVFEV+ATNGDTHLGG DFD RV++YF
Sbjct:   32 YGTIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDRLIGDAAKNQLTINPENTIFDAKRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDNKQFTPEEVSAMVLVKMKEIAESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKDGERNILVFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYF 271
[Close]
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Celegans
Match: hsp-3 (Heat shock 70 kDa protein C [Source:UniProtKB/Swiss-Prot;Acc:P27420])

HSP 1 Score: 404.06 bits (1037), Expect = 9.787e-138
Identity = 195/240 (81.25%), Postives = 222/240 (92.50%), Query Frame = 3 
Query:  162 YGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFT-QESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            YGT+IGIDLGTTYSCVGV+K+GRVEIIANDQGNRITPSYVAF+  + +RLIGDAAKNQLT NPENTIFD KR IGR ++D+TV+ DIK++PF VI+K+NKP V+VKVG +N+ F PEE+SAMVL KMKEIAESYLGK V +AVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDKK+GE+NILVFDLGGGTFDVS+LTIDNGVFEV+ATNGDTHLGG DFD RV++YF
Sbjct:   32 YGTIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDRLIGDAAKNQLTINPENTIFDAKRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDNKQFTPEEVSAMVLVKMKEIAESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKDGERNILVFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYF 271
[Close]
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Celegans
Match: hsp-3 (Heat shock 70 kDa protein C [Source:UniProtKB/Swiss-Prot;Acc:P27420])

HSP 1 Score: 404.06 bits (1037), Expect = 9.787e-138
Identity = 195/240 (81.25%), Postives = 222/240 (92.50%), Query Frame = 3 
Query:  162 YGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFT-QESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            YGT+IGIDLGTTYSCVGV+K+GRVEIIANDQGNRITPSYVAF+  + +RLIGDAAKNQLT NPENTIFD KR IGR ++D+TV+ DIK++PF VI+K+NKP V+VKVG +N+ F PEE+SAMVL KMKEIAESYLGK V +AVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDKK+GE+NILVFDLGGGTFDVS+LTIDNGVFEV+ATNGDTHLGG DFD RV++YF
Sbjct:   32 YGTIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDRLIGDAAKNQLTINPENTIFDAKRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDNKQFTPEEVSAMVLVKMKEIAESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKDGERNILVFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYF 271
[Close]
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Celegans
Match: hsp-3 (Heat shock 70 kDa protein C [Source:UniProtKB/Swiss-Prot;Acc:P27420])

HSP 1 Score: 404.06 bits (1037), Expect = 9.787e-138
Identity = 195/240 (81.25%), Postives = 222/240 (92.50%), Query Frame = 3 
Query:  162 YGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFT-QESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            YGT+IGIDLGTTYSCVGV+K+GRVEIIANDQGNRITPSYVAF+  + +RLIGDAAKNQLT NPENTIFD KR IGR ++D+TV+ DIK++PF VI+K+NKP V+VKVG +N+ F PEE+SAMVL KMKEIAESYLGK V +AVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDKK+GE+NILVFDLGGGTFDVS+LTIDNGVFEV+ATNGDTHLGG DFD RV++YF
Sbjct:   32 YGTIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDRLIGDAAKNQLTINPENTIFDAKRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDNKQFTPEEVSAMVLVKMKEIAESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKDGERNILVFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYF 271
[Close]
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Celegans
Match: hsp-3 (Heat shock 70 kDa protein C [Source:UniProtKB/Swiss-Prot;Acc:P27420])

HSP 1 Score: 404.06 bits (1037), Expect = 9.787e-138
Identity = 195/240 (81.25%), Postives = 222/240 (92.50%), Query Frame = 3 
Query:  162 YGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFT-QESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            YGT+IGIDLGTTYSCVGV+K+GRVEIIANDQGNRITPSYVAF+  + +RLIGDAAKNQLT NPENTIFD KR IGR ++D+TV+ DIK++PF VI+K+NKP V+VKVG +N+ F PEE+SAMVL KMKEIAESYLGK V +AVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDKK+GE+NILVFDLGGGTFDVS+LTIDNGVFEV+ATNGDTHLGG DFD RV++YF
Sbjct:   32 YGTIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDRLIGDAAKNQLTINPENTIFDAKRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDNKQFTPEEVSAMVLVKMKEIAESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKDGERNILVFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYF 271
[Close]
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Match: Hsc70-3 (gene:FBgn0001218 transcript:FBtr0073610)

HSP 1 Score: 406.757 bits (1044), Expect = 1.012e-138
Identity = 194/238 (81.51%), Postives = 215/238 (90.34%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            GTVIGIDLGTTYSCVGV+K+GRVEIIANDQGNRITPSYVAFT + ERLIGDAAKNQLT+NPENT+FD KR IGR + D  V+ DIK +PF V+ KN+KPH+ V   +  ++FAPEEISAMVLGKMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAG I+GL V+RIINEPTAAAIAYGLDKKEGEKN+LVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+D+F
Sbjct:   29 GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHF 266
[Close]
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Match: Hsc70-3 (gene:FBgn0001218 transcript:FBtr0345166)

HSP 1 Score: 406.757 bits (1044), Expect = 1.012e-138
Identity = 194/238 (81.51%), Postives = 215/238 (90.34%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            GTVIGIDLGTTYSCVGV+K+GRVEIIANDQGNRITPSYVAFT + ERLIGDAAKNQLT+NPENT+FD KR IGR + D  V+ DIK +PF V+ KN+KPH+ V   +  ++FAPEEISAMVLGKMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAG I+GL V+RIINEPTAAAIAYGLDKKEGEKN+LVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+D+F
Sbjct:   29 GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHF 266
[Close]
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Match: Hsc70-3 (gene:FBgn0001218 transcript:FBtr0073609)

HSP 1 Score: 406.757 bits (1044), Expect = 1.012e-138
Identity = 194/238 (81.51%), Postives = 215/238 (90.34%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            GTVIGIDLGTTYSCVGV+K+GRVEIIANDQGNRITPSYVAFT + ERLIGDAAKNQLT+NPENT+FD KR IGR + D  V+ DIK +PF V+ KN+KPH+ V   +  ++FAPEEISAMVLGKMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAG I+GL V+RIINEPTAAAIAYGLDKKEGEKN+LVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+D+F
Sbjct:   29 GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHF 266
[Close]
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Match: Hsc70-3 (gene:FBgn0001218 transcript:FBtr0073611)

HSP 1 Score: 406.757 bits (1044), Expect = 1.012e-138
Identity = 194/238 (81.51%), Postives = 215/238 (90.34%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            GTVIGIDLGTTYSCVGV+K+GRVEIIANDQGNRITPSYVAFT + ERLIGDAAKNQLT+NPENT+FD KR IGR + D  V+ DIK +PF V+ KN+KPH+ V   +  ++FAPEEISAMVLGKMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAG I+GL V+RIINEPTAAAIAYGLDKKEGEKN+LVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+D+F
Sbjct:   29 GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHF 266
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Match: Hsc70-3 (gene:FBgn0001218 transcript:FBtr0073608)

HSP 1 Score: 406.757 bits (1044), Expect = 1.012e-138
Identity = 194/238 (81.51%), Postives = 215/238 (90.34%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            GTVIGIDLGTTYSCVGV+K+GRVEIIANDQGNRITPSYVAFT + ERLIGDAAKNQLT+NPENT+FD KR IGR + D  V+ DIK +PF V+ KN+KPH+ V   +  ++FAPEEISAMVLGKMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAG I+GL V+RIINEPTAAAIAYGLDKKEGEKN+LVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+D+F
Sbjct:   29 GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHF 266
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Zebrafish
Match: hspa5 (heat shock protein 5 [Source:NCBI gene;Acc:378848])

HSP 1 Score: 416.001 bits (1068), Expect = 3.171e-142
Identity = 204/267 (76.40%), Postives = 234/267 (87.64%), Query Frame = 3 
Query:   90 ILCINVVIS---YATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGE-ENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            +LC+ ++++   +A E+ K     K+  GTVIGIDLGTTYSCVGV+K+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLTSNPENT+FD KR IGR + D +V+QDIK +PF VI K NKPH+Q+ +G  + + FAPEEISAMVL KMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDK++GEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+++F
Sbjct:    3 LLCLFLLVAGSVFAEEDDK-----KESVGTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTTEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWGDSSVQQDIKYFPFKVIEKKNKPHIQLDIGSGQMKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKRDGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 264
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Zebrafish
Match: hspa8 (heat shock protein 8 [Source:NCBI gene;Acc:573376])

HSP 1 Score: 362.844 bits (930), Expect = 8.732e-122
Identity = 175/239 (73.22%), Postives = 209/239 (87.45%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP NT+FD KR IGR FDD  V+ D+K++PF VIN N++P VQV+   E++ F PEEIS+MVL KMKEIAE+YLGK V++AV+TVPAYFND+QRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGG DFD R++++F
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDGVVQSDMKHWPFNVINDNSRPKVQVEYKGESKSFYPEEISSMVLTKMKEIAEAYLGKTVSNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Zebrafish
Match: hspa8 (heat shock protein 8 [Source:NCBI gene;Acc:573376])

HSP 1 Score: 362.844 bits (930), Expect = 1.352e-121
Identity = 175/239 (73.22%), Postives = 209/239 (87.45%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP NT+FD KR IGR FDD  V+ D+K++PF VIN N++P VQV+   E++ F PEEIS+MVL KMKEIAE+YLGK V++AV+TVPAYFND+QRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGG DFD R++++F
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDGVVQSDMKHWPFNVINDNSRPKVQVEYKGESKSFYPEEISSMVLTKMKEIAEAYLGKTVSNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Zebrafish
Match: hspa8 (heat shock protein 8 [Source:NCBI gene;Acc:573376])

HSP 1 Score: 362.844 bits (930), Expect = 1.352e-121
Identity = 175/239 (73.22%), Postives = 209/239 (87.45%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP NT+FD KR IGR FDD  V+ D+K++PF VIN N++P VQV+   E++ F PEEIS+MVL KMKEIAE+YLGK V++AV+TVPAYFND+QRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGG DFD R++++F
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDGVVQSDMKHWPFNVINDNSRPKVQVEYKGESKSFYPEEISSMVLTKMKEIAEAYLGKTVSNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Zebrafish
Match: hspa8 (heat shock protein 8 [Source:NCBI gene;Acc:573376])

HSP 1 Score: 362.844 bits (930), Expect = 1.352e-121
Identity = 175/239 (73.22%), Postives = 209/239 (87.45%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP NT+FD KR IGR FDD  V+ D+K++PF VIN N++P VQV+   E++ F PEEIS+MVL KMKEIAE+YLGK V++AV+TVPAYFND+QRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGG DFD R++++F
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDGVVQSDMKHWPFNVINDNSRPKVQVEYKGESKSFYPEEISSMVLTKMKEIAEAYLGKTVSNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Match: nsg1 (neuronal vesicle trafficking associated 1 [Source:Xenbase;Acc:XB-GENE-992527])

HSP 1 Score: 420.239 bits (1079), Expect = 2.294e-144
Identity = 203/272 (74.63%), Postives = 233/272 (85.66%), Query Frame = 3 
Query:   63 MLNKNFICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            M+      ++L ++  +  A     D +  ++D GTV+GIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLTSNPENT+FD KR IGR ++D +V+QDIK  PF VI +  KP++QV +G++ + FAPEEISAMVL KMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+++F
Sbjct:    1 MVTMKLFALVLLVSASVFAA-----DDDDKREDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDIGDQMKTFAPEEISAMVLVKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 267
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Match: nsg1 (neuronal vesicle trafficking associated 1 [Source:Xenbase;Acc:XB-GENE-992527])

HSP 1 Score: 420.624 bits (1080), Expect = 6.907e-144
Identity = 203/272 (74.63%), Postives = 233/272 (85.66%), Query Frame = 3 
Query:   63 MLNKNFICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            M+      ++L ++  +  A     D +  ++D GTV+GIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLTSNPENT+FD KR IGR ++D +V+QDIK  PF VI +  KP++QV +G++ + FAPEEISAMVL KMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+++F
Sbjct:    1 MVTMKLFALVLLVSASVFAA-----DDDDKREDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDIGDQMKTFAPEEISAMVLVKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 267
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Match: nsg1 (neuronal vesicle trafficking associated 1 [Source:Xenbase;Acc:XB-GENE-992527])

HSP 1 Score: 418.313 bits (1074), Expect = 6.048e-143
Identity = 203/272 (74.63%), Postives = 232/272 (85.29%), Query Frame = 3 
Query:   63 MLNKNFICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            M       ++L ++  +  A     D +  ++D GTV+GIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLTSNPENT+FD KR IGR ++D +V+QDIK  PF VI +  KP++QV +G++ + FAPEEISAMVL KMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+++F
Sbjct:    1 MFFPTLFALVLLVSASVFAA-----DDDDKREDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDIGDQMKTFAPEEISAMVLVKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 267
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Match: nsg1 (neuronal vesicle trafficking associated 1 [Source:Xenbase;Acc:XB-GENE-992527])

HSP 1 Score: 417.927 bits (1073), Expect = 6.942e-143
Identity = 204/269 (75.84%), Postives = 234/269 (86.99%), Query Frame = 3 
Query:   75 NFI-CIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            NF+  ++L ++  +  A     D +  ++D GTV+GIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLTSNPENT+FD KR IGR ++D +V+QDIK  PF VI +  KP++QV +G++ + FAPEEISAMVL KMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+++F
Sbjct:    5 NFLFALVLLVSASVFAA-----DDDDKREDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDIGDQMKTFAPEEISAMVLVKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 268
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Match: nsg1 (neuronal vesicle trafficking associated 1 [Source:Xenbase;Acc:XB-GENE-992527])

HSP 1 Score: 417.157 bits (1071), Expect = 1.394e-142
Identity = 200/247 (80.97%), Postives = 224/247 (90.69%), Query Frame = 3 
Query:  138 DSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            D +  ++D GTV+GIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLTSNPENT+FD KR IGR ++D +V+QDIK  PF VI +  KP++QV +G++ + FAPEEISAMVL KMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+++F
Sbjct:   21 DDDDKREDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDIGDQMKTFAPEEISAMVLVKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 267
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Mouse
Match: Hspa5 (heat shock protein 5 [Source:MGI Symbol;Acc:MGI:95835])

HSP 1 Score: 412.92 bits (1060), Expect = 5.412e-141
Identity = 200/250 (80.00%), Postives = 224/250 (89.60%), Query Frame = 3 
Query:  132 KKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGE-ENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            + + E  K+D GTV+GIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLTSNPENT+FD KR IGR ++D +V+QDIK  PF V+ K  KP++QV +G  + + FAPEEISAMVL KMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDK+EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+++F
Sbjct:   18 RAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 267
[Close]
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Mouse
Match: Hspa5 (heat shock protein 5 [Source:MGI Symbol;Acc:MGI:95835])

HSP 1 Score: 412.92 bits (1060), Expect = 5.412e-141
Identity = 200/250 (80.00%), Postives = 224/250 (89.60%), Query Frame = 3 
Query:  132 KKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGE-ENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            + + E  K+D GTV+GIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLTSNPENT+FD KR IGR ++D +V+QDIK  PF V+ K  KP++QV +G  + + FAPEEISAMVL KMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDK+EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+++F
Sbjct:   18 RAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 267
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Mouse
Match: Hspa8 (heat shock protein 8 [Source:MGI Symbol;Acc:MGI:105384])

HSP 1 Score: 362.073 bits (928), Expect = 3.329e-121
Identity = 173/239 (72.38%), Postives = 207/239 (86.61%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP NT+FD KR IGR FDD  V+ D+K++PF+V+N   +P VQV+   E + F PEE+S+MVL KMKEIAE+YLGK VT+AVVTVPAYFND+QRQATKDAGTI+GLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGG DFD R++++F
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Mouse
Match: Hspa1a (heat shock protein 1A [Source:MGI Symbol;Acc:MGI:96244])

HSP 1 Score: 357.836 bits (917), Expect = 1.142e-119
Identity = 173/238 (72.69%), Postives = 204/238 (85.71%), Query Frame = 3 
Query:  168 TVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKK-EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            T IGIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP+NT+FD KR IGR F D  V+ D+K++PF V+N  +KP VQV    E+R F PEEIS+MVL KMKEIAE+YLG  VT+AV+TVPAYFND+QRQATKDAG I+GLNVLRIINEPTAAAIAYGLD+  +GE+N+L+FDLGGGTFDVS+LTID+G+FEV AT GDTHLGG DFD R++ +F
Sbjct:    5 TAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHF 241
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Mouse
Match: Hspa1b (heat shock protein 1B [Source:MGI Symbol;Acc:MGI:99517])

HSP 1 Score: 357.836 bits (917), Expect = 1.336e-119
Identity = 173/238 (72.69%), Postives = 204/238 (85.71%), Query Frame = 3 
Query:  168 TVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKK-EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            T IGIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP+NT+FD KR IGR F D  V+ D+K++PF V+N  +KP VQV    E+R F PEEIS+MVL KMKEIAE+YLG  VT+AV+TVPAYFND+QRQATKDAG I+GLNVLRIINEPTAAAIAYGLD+  +GE+N+L+FDLGGGTFDVS+LTID+G+FEV AT GDTHLGG DFD R++ +F
Sbjct:    5 TAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHF 241
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BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Match: sp|Q16956|BIP_APLCA (Endoplasmic reticulum chaperone BiP OS=Aplysia californica OX=6500 PE=1 SV=1)

HSP 1 Score: 424.476 bits (1090), Expect = 1.392e-144
Identity = 204/267 (76.40%), Postives = 233/267 (87.27%), Query Frame = 3 
Query:   78 FICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
             + I+   N+++    + + + +  K + GTVIGIDLGTTYSCVGVFK+GRV+IIANDQGNRITPSYVAFT + ERLIGDAAKNQLTSNPENTIFDVKR IGR FDD++V+ DIK YPF V N NNKPH+Q   GE +R FAPEEISAMVL KM++IAE YLGK++T+AVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVV+TNGDTHLGG DFD RV+++F
Sbjct:    9 LLVILFSSNLLVRADGDEEDEGDKKKSEVGTVIGIDLGTTYSCVGVFKNGRVDIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTSNPENTIFDVKRLIGRTFDDKSVQHDIKFYPFKVTNANNKPHIQAATGEGDRSFAPEEISAMVLSKMRDIAEEYLGKKITNAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVSTNGDTHLGGEDFDQRVMEHF 275
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BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Match: sp|Q90593|BIP_CHICK (Endoplasmic reticulum chaperone BiP OS=Gallus gallus OX=9031 GN=HSPA5 PE=1 SV=1)

HSP 1 Score: 417.927 bits (1073), Expect = 3.604e-142
Identity = 203/250 (81.20%), Postives = 224/250 (89.60%), Query Frame = 3 
Query:  132 KKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGE-ENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            + D E  K+D GTV+GIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLTSNPENT+FD KR IGR ++D +V+QDIK  PF V+ K  KPH+QV VG  + + FAPEEISAMVL KMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDK+EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+++F
Sbjct:   15 RADDEEKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKYLPFKVVEKKAKPHIQVDVGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 264
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BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Match: sp|Q24895|BIP_ECHMU (Endoplasmic reticulum chaperone BiP OS=Echinococcus multilocularis OX=6211 GN=GRP78 PE=2 SV=1)

HSP 1 Score: 417.542 bits (1072), Expect = 4.874e-142
Identity = 206/263 (78.33%), Postives = 232/263 (88.21%), Query Frame = 3 
Query:   90 ILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            +LCI + +S+        +S K++YGTVIGIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAF+ + ERLIGDAAKNQLTSNP+NT+FD KR IGR +DD+ V+ DIK YPF VINKNNKP+++V+VG E + FAPEE+SAMVL KMKEIAE+YLG  VTHAVVTVPAYFNDAQRQATKDAG I+GL VLRIINEPTAAAIAYGLDKK+ EKNILVFDLGGGTFDVSLLTIDNGVFEVVAT+GDTHLGG DFD R+IDYF
Sbjct:   11 LLCI-LTLSHC-------KSGKEEYGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFSGDGERLIGDAAKNQLTSNPKNTLFDAKRLIGRDYDDKDVQGDIKRYPFKVINKNNKPYMKVQVGSEEKGFAPEEVSAMVLSKMKEIAEAYLGTEVTHAVVTVPAYFNDAQRQATKDAGAIAGLTVLRIINEPTAAAIAYGLDKKDTEKNILVFDLGGGTFDVSLLTIDNGVFEVVATSGDTHLGGEDFDQRLIDYF 265
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BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Match: sp|Q0VCX2|BIP_BOVIN (Endoplasmic reticulum chaperone BiP OS=Bos taurus OX=9913 GN=HSPA5 PE=2 SV=1)

HSP 1 Score: 413.69 bits (1062), Expect = 1.997e-140
Identity = 201/250 (80.40%), Postives = 224/250 (89.60%), Query Frame = 3 
Query:  132 KKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGE-ENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            + + E  K+D GTV+GIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLTSNPENT+FD KR IGR ++D +V+QDIK  PF V+ K  KP++QV VG  + + FAPEEISAMVL KMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDK+EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+++F
Sbjct:   18 RAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDVGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 267
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BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Match: sp|Q3S4T7|BIP_ICTTR (Endoplasmic reticulum chaperone BiP OS=Ictidomys tridecemlineatus OX=43179 GN=HSPA5 PE=2 SV=1)

HSP 1 Score: 412.92 bits (1060), Expect = 3.677e-140
Identity = 200/248 (80.65%), Postives = 223/248 (89.92%), Query Frame = 3 
Query:  138 DSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGE-ENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            + E  K+D GTV+GIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLTSNPENT+FD KR IGR ++D +V+QDIK  PF V+ K  KP++QV +G  + + FAPEEISAMVL KMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDK+EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+++F
Sbjct:   19 EEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 266
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BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Match: A0A1I8HNI7 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032526g1 PE=3 SV=1)

HSP 1 Score: 441.425 bits (1134), Expect = 1.500e-148
Identity = 215/282 (76.24%), Postives = 247/282 (87.59%), Query Frame = 3 
Query:   39 LLHDFKIMMLNKN--FICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            LL+     ++NK   ++ +++CI + ++ + + K D +  K+D GTVIGIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLT+NPENTIFDVKR IGR + D+ V++DIK  P+ V+NKN+KP +QV+VG E + FAPEEISAMVLGKMKEIAESYLGK+VTHAVVTVPAYFNDAQRQATKDAG I+GLNV+RIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV++YF
Sbjct:    1 LLNSQTQTIMNKQLFYLAMLVCIGLALADSDKEKTD-QKKKEDVGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTTNPENTIFDVKRIIGRNYADDVVQKDIKLLPYTVVNKNSKPAIQVQVGSETKTFAPEEISAMVLGKMKEIAESYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEYF 281
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BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Match: A0A267GFX2 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032526g2 PE=3 SV=1)

HSP 1 Score: 439.884 bits (1130), Expect = 6.728e-148
Identity = 215/282 (76.24%), Postives = 246/282 (87.23%), Query Frame = 3 
Query:   39 LLHDFKIMMLNKN--FICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            LL+      +NK   ++ +++CI + ++ + + K D +  K+D GTVIGIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLT+NPENTIFDVKR IGR + D+ V++DIK  P+ V+NKN+KP +QV+VG E + FAPEEISAMVLGKMKEIAESYLGK+VTHAVVTVPAYFNDAQRQATKDAG I+GLNV+RIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV++YF
Sbjct:    1 LLNSQTQTKMNKQLFYLAMLVCIGLALADSDKEKTD-QKKKEDVGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTTNPENTIFDVKRIIGRNYADDVVQKDIKLLPYTVVNKNSKPAIQVQVGSEAKTFAPEEISAMVLGKMKEIAESYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEYF 281
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BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Match: A0A430QQ45 (Heat shock 70kDa protein 5 (Fragment) OS=Schistosoma bovis OX=6184 GN=DC041_0002292 PE=3 SV=1)

HSP 1 Score: 437.958 bits (1125), Expect = 1.921e-147
Identity = 214/277 (77.26%), Postives = 237/277 (85.56%), Query Frame = 3 
Query:   51 FKIMMLNKNFICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYFS 881
            F   +L    +C++ C               E  K+DYGTVIGIDLGTTYSCVGVF+ GRVEIIANDQGNRITPSYVAFT E ERLIGDAAK+QLTSNPENTIFDVKRFIGR FD+ TV+ DI +YPF V+NK NKP+V+V VG E + FAPEEISAMVLGKMKEIAESYLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLN+LRIINEPTAAAIAYGLDKK+GEKNIL+FDLGGGTFDVSLLTI+NGVFEVVATNGDTHLGG DFD RV+D+F+
Sbjct:   10 FSCFLLLSYILCLVSC---------------EEKKEDYGTVIGIDLGTTYSCVGVFQGGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKSQLTSNPENTIFDVKRFIGRKFDEPTVQNDITHYPFSVVNKKNKPYVEVHVGSEVKTFAPEEISAMVLGKMKEIAESYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNILRIINEPTAAAIAYGLDKKDGEKNILIFDLGGGTFDVSLLTIENGVFEVVATNGDTHLGGEDFDQRVVDHFA 271
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BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Match: A0A1I8H5I1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032526g3 PE=3 SV=1)

HSP 1 Score: 438.343 bits (1126), Expect = 2.268e-147
Identity = 214/285 (75.09%), Postives = 246/285 (86.32%), Query Frame = 3 
Query:   39 LLHDFKIMMLNKN--FICIILCINVVIS---YATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            LL+      +NK   ++ +++CI + ++    + + +K  +  K+D GTVIGIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLT+NPENTIFDVKR IGR + D+ V++DIK  P+ V+NKN+KP +QV+VG E + FAPEEISAMVLGKMKEIAESYLGK+VTHAVVTVPAYFNDAQRQATKDAG I+GLNV+RIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV++YF
Sbjct:    1 LLNSQTQTKMNKQLFYLAMLVCIGLALADSDKSADKEKTDQKKKEDVGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTTNPENTIFDVKRIIGRNYADDVVQKDIKLLPYTVVNKNSKPAIQVQVGSEAKTFAPEEISAMVLGKMKEIAESYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEYF 285
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BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Match: A0A095CGL8 (78 kDa glucose-regulated protein (Fragment) OS=Schistosoma haematobium OX=6185 GN=MS3_10713 PE=3 SV=1)

HSP 1 Score: 435.261 bits (1118), Expect = 1.461e-146
Identity = 212/268 (79.10%), Postives = 236/268 (88.06%), Query Frame = 3 
Query:   78 FICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYFS 881
            F C++L   ++   + E KK+      DYGTVIGIDLGTTYSCVGVF+ GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLTSNPENTIFDVKR IGR FD+ TV+ DI +YPF V+NK NKP+++V VG E + FAPEEISAMVLGKMKE AESYLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLN+LRIINEPTAAAIAYGLDKK+GEKNIL+FDLGGGTFDVSLLTI+NGVFEVVATNGDTHLGG DFD RV+D+F+
Sbjct:    2 FSCVLLLSYILCLVSCEEKKE------DYGTVIGIDLGTTYSCVGVFQGGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTIFDVKRLIGRKFDESTVQNDITHYPFSVVNKKNKPYIEVHVGSEVKTFAPEEISAMVLGKMKEFAESYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNILRIINEPTAAAIAYGLDKKDGEKNILIFDLGGGTFDVSLLTIENGVFEVVATNGDTHLGGEDFDQRVVDHFA 263
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Match: hspa5 (heat shock protein family A (Hsp70) member 5 [Source:NCBI gene;Acc:103030781])

HSP 1 Score: 415.231 bits (1066), Expect = 5.797e-142
Identity = 206/277 (74.37%), Postives = 236/277 (85.20%), Query Frame = 3 
Query:   51 FKIMMLNKNFICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGE-ENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
             KI+ L   F+ ++ C+     YA     D +  K++ GTV+GIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLTSNPENT+FD KR IGR + D +V+QD+K +PF V+ K +KPH+QV +G  + + FAPEEISAMVL KMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDKK+GEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+++F
Sbjct:    1 MKILCL---FMLVVGCV-----YA-----DDDDKKENVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWGDSSVQQDVKYFPFKVLEKKSKPHIQVDIGAGQLKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKDGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 264
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Match: hspa8b (heat shock cognate 70 kDa protein-like [Source:NCBI gene;Acc:103047344])

HSP 1 Score: 363.229 bits (931), Expect = 9.186e-122
Identity = 176/239 (73.64%), Postives = 207/239 (86.61%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP NT+FD KR IGR FDD  V+ D+K++PF VIN + +P VQV+   E + F PEEIS+MVL KMKEIAE+YLGK VT+AVVTVPAYFND+QRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGG DFD R++++F
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFTVINDSTRPKVQVEYKGETKAFYPEEISSMVLVKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGSERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Match: hspa8 (heat shock cognate 71 kDa protein [Source:NCBI gene;Acc:103043364])

HSP 1 Score: 361.688 bits (927), Expect = 3.823e-121
Identity = 176/239 (73.64%), Postives = 206/239 (86.19%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP NTIFD KR IGR FDD  V+ D+K++PF VIN + +P VQV    E + F PEEIS+MVL KMKEIAE+YLGK VT+AV+TVPAYFND+QRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGG DFD R++++F
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTIFDAKRLIGRRFDDGVVQSDMKHWPFTVINDSTRPKVQVDYKGEAKSFYPEEISSMVLVKMKEIAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGSERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Match: ENSAMXT00000037064.1 (heat shock 70 kDa protein [Source:NCBI gene;Acc:111193176])

HSP 1 Score: 359.377 bits (921), Expect = 2.826e-120
Identity = 172/239 (71.97%), Postives = 207/239 (86.61%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDK-KEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            G  IGIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP NT+FD KR IGR FDD  V+ D+K++PF V++   KP VQV+   E + F PEEIS+MVL KMKEIAE+YLG++VT+AV+TVPAYFND+QRQATKDAG I+GLNVLRIINEPTAAAIAYGLDK K+GE+++L+FDLGGGTFDVS+LTI++G+FEV AT GDTHLGG DFD R++++F
Sbjct:    6 GVAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPNNTVFDAKRLIGRKFDDPVVQSDMKHWPFQVVSDGGKPKVQVEYKGEQKTFNPEEISSMVLVKMKEIAEAYLGQKVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGKKGERHVLIFDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRLVNHF 243
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Match: ENSAMXT00000055474.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001455.1:150188:156169:-1 gene:ENSAMXG00000043809.1 transcript:ENSAMXT00000055474.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 357.451 bits (916), Expect = 5.498e-120
Identity = 172/239 (71.97%), Postives = 206/239 (86.19%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDK-KEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            G  IGIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP NT+FD KR IGR FDD  V+ D+K++PF V++   KP VQV+   E + F PEEIS+MVL KMKEIAE+YLG++VT+AV+TVPAYFND+QRQATKDAG I+GLNVLRIINEPTAAAIAYGLDK K GE+++L+FDLGGGTFDVS+LTI++G+FEV AT GDTHLGG DFD R++++F
Sbjct:    6 GVAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPNNTVFDAKRLIGRKFDDPVVQSDMKHWPFQVVSDGGKPKVQVEHKGEQKTFYPEEISSMVLVKMKEIAEAYLGQKVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGKTGERHVLIFDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRLVNHF 243
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Sea Lamprey
Match: hspa5 (heat shock protein 5 [Source:NCBI gene;Acc:378848])

HSP 1 Score: 414.846 bits (1065), Expect = 2.142e-142
Identity = 202/248 (81.45%), Postives = 223/248 (89.92%), Query Frame = 3 
Query:  138 DSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKV-GEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            + +  K++ GTVIGIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLTSNPENT+FD KR IGR + D TV+ DIK +PF V+ K  KPH+QV+V   E++ FAPEEISAMVL KMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTID+GVFEVVATNGDTHLGG DFD RV+++F
Sbjct:   24 EDDKEKENMGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTSNPENTVFDAKRLIGRSWTDPTVQHDIKFWPFTVLEKKGKPHIQVEVIAGESKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDHGVFEVVATNGDTHLGGEDFDQRVMEHF 271
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Sea Lamprey
Match: hspa9 (heat shock protein 9 [Source:ZFIN;Acc:ZDB-GENE-030828-12])

HSP 1 Score: 266.929 bits (681), Expect = 6.762e-85
Identity = 133/238 (55.88%), Postives = 171/238 (71.85%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            G VIGIDLGTT SCV V +  + +++ N +G R TPS VAFT + ERL+G  AK Q  +NP NT +  KR IGR FDD  V++D+ N  + ++  +N       V    ++++P +I A VL KMKE AE+++G  V +AV+TVPAYFND+QRQATKDAG ISGLNVLR+INEPTAAA+AYGLDK + +K I V+DLGGGTFD+S+L I  GVFEV +TNGDT LGG DFD  ++ Y 
Sbjct:   53 GAVIGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYATKRLIGRRFDDSDVQKDMNNLSYKIVRASNG---DAWVEAHGKMYSPSQIGAFVLLKMKETAENFMGTSVKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKAD-DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDNALLKYI 286
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Sea Lamprey
Match: hspa13 (heat shock protein 70 family, member 13 [Source:ZFIN;Acc:ZDB-GENE-070410-58])

HSP 1 Score: 189.504 bits (480), Expect = 4.445e-57
Identity = 101/240 (42.08%), Postives = 148/240 (61.67%), Query Frame = 3 
Query:  171 VIGIDLGTTYSCVGVFKSG--RVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVK-VGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYFS 881
            ++GIDLGTTY  +GV+ +G   VE++A+  G R  PS VA   +   L G  A  Q   NP  T++D KRFIGR F    ++++   Y F V   + +    ++  G   +   PE + A +L +++ +AE  LG  V +AV+ VPA F++ QR +T  A T++GL VLR++NEPTAAA+AYGL ++E   ++LV DLGGGT DVSLLT   G+F   A  G+ HLGG DF  R++++ +
Sbjct:   33 IVGIDLGTTYCSIGVYHAGVGEVEVLADADGRRAFPSVVAAGSDGRVLAGFPALQQAADNPHATLYDAKRFIGRAFSPGELEREAGRYQFTVRQVSGEVVFVLRGHGGAEQTVTPEWVGAQMLDQLRLLAEERLGLPVRYAVLAVPAEFDERQRNSTIKAATMAGLEVLRVVNEPTAAALAYGLHEEESVSSVLVVDLGGGTTDVSLLTKQGGMFFTRAMAGNNHLGGQDFTQRLVEHLT 272
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Sea Lamprey
Match: hspa14 (heat shock protein 14 [Source:NCBI gene;Acc:565232])

HSP 1 Score: 153.68 bits (387), Expect = 2.448e-43
Identity = 80/238 (33.61%), Postives = 137/238 (57.56%), Query Frame = 3 
Query:  174 IGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEK--NILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYFS 881
            +G+ LG+T +CV ++K GR ++IAND G+R+TP+ VAF ++SE+++G AAK     N   T+  VKR +G  F+D+ V++ I +    VI K+  P   +  G   +     E++ ++L KMKE A   +G     AV+T P  F   Q    + A   +G NVLRI++EP AA +A+G+ ++       +LV+ LGG     + + +++G++ V+ +  D  +GG +F   + +Y +
Sbjct:    4 VGVHLGSTCACVAIYKDGRADVIANDAGDRVTPAMVAF-RDSEKIVGLAAKQGRIRNATTTVVGVKRILGHRFEDDVVQKYISSSSCPVIEKDGCPVFSINNGTVKKHITRHEVATLILQKMKETALFAVGADAKDAVITTPLNFTTQQVDELRQAAESAGFNVLRILSEPAAALLAFGIGQESSHSKCKVLVYKLGGTCAYATAIEVNSGLYRVLGSVSDDTVGGEEFTEALAEYLA 240
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Match: KAR2 (ATPase involved in protein import into the ER; also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p [Source:SGD;Acc:S000003571])

HSP 1 Score: 367.081 bits (941), Expect = 1.070e-123
Identity = 173/238 (72.69%), Postives = 209/238 (87.82%), Query Frame = 3 
Query:  156 DDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVI 869
            ++YGTVIGIDLGTTYSCV V K+G+ EI+AN+QGNRITPSYVAFT + ERLIGDAAKNQ+ +NP+NTIFD+KR IG  ++D +V++DIK+ PF V+NK+ KP V+V V  E ++F PEEIS M+LGKMK+IAE YLG +VTHAVVTVPAYFNDAQRQATKDAGTI+GLNVLRI+NEPTAAAIAYGLDK + E  I+V+DLGGGTFDVSLL+I+NGVFEV AT+GDTHLGG DFD +++
Sbjct:   47 ENYGTVIGIDLGTTYSCVAVMKNGKTEILANEQGNRITPSYVAFT-DDERLIGDAAKNQVAANPQNTIFDIKRLIGLKYNDRSVQKDIKHLPFNVVNKDGKPAVEVSVKGEKKVFTPEEISGMILGKMKQIAEDYLGTKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVLRIVNEPTAAAIAYGLDKSDKEHQIIVYDLGGGTFDVSLLSIENGVFEVQATSGDTHLGGEDFDYKIV 283
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Match: SSA1 (ATPase involved in protein folding and NLS-directed nuclear transport; member of HSP70 family; required for ubiquitin-dependent degradation of short-lived proteins; forms chaperone complex with Ydj1p; localized to nucleus, cytoplasm, cell wall; 98% identical to paralog Ssa2p with different functional specificity in propagation of yeast [URE3] prions, vacuolar-mediated degradations of gluconeogenesis enzymes; general targeting factor of Hsp104p to prion fibrils [Source:SGD;Acc:S000000004])

HSP 1 Score: 344.739 bits (883), Expect = 1.606e-115
Identity = 164/236 (69.49%), Postives = 199/236 (84.32%), Query Frame = 3 
Query:  171 VIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
             +GIDLGTTYSCV  F + RV+IIANDQGNR TPS+VAFT ++ERLIGDAAKNQ   NP NT+FD KR IGR F+D  V+ D+K++PF +I+ + KP +QV+   E + F PE+IS+MVLGKMKE AESYLG +V  AVVTVPAYFND+QRQATKDAGTI+GLNVLRIINEPTAAAIAYGLDKK  E+++L+FDLGGGTFDVSLL+I++G+FEV AT GDTHLGG DFD R++++F
Sbjct:    4 AVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFT-DTERLIGDAAKNQAAMNPSNTVFDAKRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEHVLIFDLGGGTFDVSLLSIEDGIFEVKATAGDTHLGGEDFDNRLVNHF 238
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Match: SSA4 (Heat shock protein that is highly induced upon stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the HSP70 family; cytoplasmic protein that concentrates in nuclei upon starvation; SSA4 has a paralog, SSA3, that arose from the whole genome duplication [Source:SGD;Acc:S000000905])

HSP 1 Score: 344.354 bits (882), Expect = 1.971e-115
Identity = 170/238 (71.43%), Postives = 194/238 (81.51%), Query Frame = 3 
Query:  171 VIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKK-EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYFS 881
             +GIDLGTTYSCV  F + RVEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ   NP NT+FD KR IGR FDD  V  D K+YPF VI+K  KP VQV+   E + F PEEIS+M+L KMKE AE++LG  V  AVVTVPAYFND+QRQATKDAGTI+GLNVLRIINEPTAAAIAYGLDKK + E N+L+FDLGGGTFDVSLL+ID GVFEV AT GDTHLGG DFD R++++ +
Sbjct:    4 AVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQAAMNPHNTVFDAKRLIGRKFDDPEVTNDAKHYPFKVIDKGGKPVVQVEYKGETKTFTPEEISSMILTKMKETAENFLGTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKSQKEHNVLIFDLGGGTFDVSLLSIDEGVFEVKATAGDTHLGGEDFDSRLVNFLA 240
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Match: SSA3 (ATPase involved in protein folding and the response to stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm; SSA3 has a paralog, SSA4, that arose from the whole genome duplication [Source:SGD;Acc:S000000171])

HSP 1 Score: 342.813 bits (878), Expect = 1.135e-114
Identity = 169/238 (71.01%), Postives = 194/238 (81.51%), Query Frame = 3 
Query:  171 VIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKK-EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYFS 881
             +GIDLGTTYSCV  F + RVEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ   NP NT+FD KR IGR FDD  V  D K++PF VI+++ KP VQV+   E + F PEEIS+MVL KMKE AE+YLG  V  AVVTVPAYFND+QRQATKDAGTI+G+NVLRIINEPTAAAIAYGLDKK   E N+L+FDLGGGTFDVSLL+ID GVFEV AT GDTHLGG DFD R++++ +
Sbjct:    4 AVGIDLGTTYSCVAHFSNDRVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQAAINPHNTVFDAKRLIGRKFDDPEVTTDAKHFPFKVISRDGKPVVQVEYKGETKTFTPEEISSMVLSKMKETAENYLGTTVNDAVVTVPAYFNDSQRQATKDAGTIAGMNVLRIINEPTAAAIAYGLDKKGRAEHNVLIFDLGGGTFDVSLLSIDEGVFEVKATAGDTHLGGEDFDNRLVNHLA 240
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Match: SSA2 (HSP70 family ATP-binding protein; involved in protein folding, vacuolar import of proteins; required for ubiquitin-dependent degradation of short-lived proteins; associated with chaperonin-containing T-complex; 98% identical to paralog Ssa1p with distinct functional specificity in propagation of yeast [URE3] prions and vacuolar-mediated degradation of gluconeogenesis enzymes; binds tRNA, has role in tRNA nuclear import during starvation [Source:SGD;Acc:S000003947])

HSP 1 Score: 341.273 bits (874), Expect = 3.003e-114
Identity = 163/236 (69.07%), Postives = 198/236 (83.90%), Query Frame = 3 
Query:  171 VIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
             +GIDLGTTYSCV  F + RV+IIANDQGNR TPS+V FT ++ERLIGDAAKNQ   NP NT+FD KR IGR F+D  V+ D+K++PF +I+ + KP +QV+   E + F PE+IS+MVLGKMKE AESYLG +V  AVVTVPAYFND+QRQATKDAGTI+GLNVLRIINEPTAAAIAYGLDKK  E+++L+FDLGGGTFDVSLL+I++G+FEV AT GDTHLGG DFD R++++F
Sbjct:    4 AVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFT-DTERLIGDAAKNQAAMNPANTVFDAKRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEHVLIFDLGGGTFDVSLLSIEDGIFEVKATAGDTHLGGEDFDNRLVNHF 238
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Match: EDO33296 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSL5])

HSP 1 Score: 414.075 bits (1063), Expect = 9.093e-142
Identity = 202/267 (75.66%), Postives = 231/267 (86.52%), Query Frame = 3 
Query:   81 ICII-LCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            IC + L  ++V +   E +K+    ++  GTVIGIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT+E ERLIGD AKNQLT+NPENT+FD KR IGR +DD +V+ D+K +PF V++KN KPHVQVKV +E + FA EEISAMVL KMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAG I+GL V+RIINEPTAAAIAYG+DKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD  V+++F
Sbjct:    7 ICTLALASSLVFADKKEERKEQ---REKVGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTEEGERLIGDGAKNQLTTNPENTVFDAKRLIGRSWDDTSVQNDLKFFPFKVVDKNKKPHVQVKVKDEIKTFAAEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGAIAGLTVMRIINEPTAAAIAYGMDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQNVMEHF 270
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Match: EDO44530 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RV88])

HSP 1 Score: 358.221 bits (918), Expect = 2.709e-120
Identity = 172/238 (72.27%), Postives = 207/238 (86.97%), Query Frame = 3 
Query:  171 VIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKK-EGEKNILVFDLGGGTFDVSLLTIDNG-VFEVVATNGDTHLGG*DFD*RVIDYF 878
             IGIDLGTTYSCVGVF++G+VEIIANDQGNR TPSYV FT ++ERL+GDAAKNQ+  NPENTIFD KR IGR +DD TV+ D+K +PF +I+ NNKP +QV+   E + FA EEIS+MVLGKMKE AE+YLG++VT AV+TVPAYFND+QRQATKDAGTI+GLNVLR+INEPTAAA+AYGLDK   GEKN+L+FDLGGGTFDVS+LTID+G +FEV +T GDTHLGG DFD R++++F
Sbjct:    6 AIGIDLGTTYSCVGVFQNGKVEIIANDQGNRTTPSYVGFT-DTERLVGDAAKNQVALNPENTIFDAKRLIGRRYDDATVQSDMKLWPFKIISDNNKPKIQVEYKGERKTFAAEEISSMVLGKMKETAEAYLGQKVTSAVITVPAYFNDSQRQATKDAGTIAGLNVLRVINEPTAAALAYGLDKSLSGEKNVLIFDLGGGTFDVSILTIDDGSLFEVKSTAGDTHLGGEDFDNRLVNHF 242
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Match: EDO37280 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG65])

HSP 1 Score: 352.058 bits (902), Expect = 8.435e-118
Identity = 168/236 (71.19%), Postives = 203/236 (86.02%), Query Frame = 3 
Query:  174 IGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAF+ ++ERLIGDAAKNQ+  NPENT+FD KR IGR FDD  V +D+ ++PF VI +  +P +QV+   E + F PEEIS+MVL KMKE AE+YLG +VT AVVTVPAYFND+QRQATKDAGTI+GLNVLRIINEPTAAAIAYGLDKK G E+N+L++DLGGGTFDVS+LTI++G+FEV +T GDTHLGG DFD +++D+F
Sbjct:    7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFS-DTERLIGDAAKNQVAMNPENTVFDAKRLIGRKFDDPVVARDMTHWPFHVIREGERPKIQVEFKGEKKSFFPEEISSMVLTKMKETAEAYLGAKVTDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGVERNVLIYDLGGGTFDVSVLTIEDGIFEVKSTAGDTHLGGEDFDNKMVDHF 241
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Match: EDO30323 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T144])

HSP 1 Score: 347.821 bits (891), Expect = 4.371e-116
Identity = 170/237 (71.73%), Postives = 200/237 (84.39%), Query Frame = 3 
Query:  171 VIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
             IGIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT E ERL+GDAAKNQ+  NP NTIFD KR IGR FDD  VK D+K++ F V+N+  +P V+V+   E + F  EEIS+MVL KMKE AE+YLG +VT AVVTVPAYFND+QRQATKDAG ISGLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+L+I++G+FEV +T+GDTHLGG DFD  ++D+F
Sbjct:    6 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDE-ERLVGDAAKNQVAMNPTNTIFDAKRLIGRRFDDPGVKDDMKHWSFEVVNEAGRPKVKVEYKGETKTFFAEEISSMVLNKMKETAEAYLGCKVTDAVVTVPAYFNDSQRQATKDAGVISGLNVLRIINEPTAAAIAYGLDKKVGQERNVLIFDLGGGTFDVSVLSIEDGIFEVKSTHGDTHLGGEDFDNNMVDFF 241
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Match: EDO47723 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLN7])

HSP 1 Score: 271.552 bits (693), Expect = 1.146e-86
Identity = 138/250 (55.20%), Postives = 179/250 (71.60%), Query Frame = 3 
Query:  129 NKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            ++  SES +   G V GIDLGTT SCV V      ++I N +G+R TPS VAFT E ERL+G  A+ Q  +NP+NT++  KR+IGR FD   +K+D+KN  + ++  +N        G   ++++P ++ A VL KMKE AESYLG  V +AVVTVPAYFND+QRQATKDAG I+GLNVLR+INEPTAAA+AYG+DK E +K I V+DLGGGTFD+S+L I  GVFEV ATNGDT+LGG DFD  ++ + 
Sbjct:    3 SRSSSESVR---GAVCGIDLGTTNSCVAVMDGKTPKVIENAEGSRTTPSVVAFTPEGERLVGAPARRQAITNPQNTLYATKRYIGRRFDAPEIKKDLKNVSYKIVRASNGDAWFEVAG---KVYSPSQVGAFVLMKMKETAESYLGTNVNNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKTE-DKIIAVYDLGGGTFDISILEIQKGVFEVKATNGDTYLGGEDFDNTLLKFL 245
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
Match: hspa5 (heat shock protein family A (Hsp70) member 5 [Source:NCBI gene;Acc:101157378])

HSP 1 Score: 418.313 bits (1074), Expect = 2.713e-143
Identity = 206/270 (76.30%), Postives = 231/270 (85.56%), Query Frame = 3 
Query:   72 KNFICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGE-ENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            K    ++L +  VI+       + E  KD  GTVIGIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLTSNPENT+FD KR IGR + D +V+QDIK +PF VI K +KPH+Q+ +G  + + FAPEEISAMVL KMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDKK+GEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+++F
Sbjct:    2 KLLWVVMLVVGAVIA-------EEEDKKDSVGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTSNPENTVFDAKRLIGRSWGDSSVQQDIKYFPFKVIEKKSKPHIQIDIGGGQMKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKDGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 264
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
Match: hspa5 (heat shock protein family A (Hsp70) member 5 [Source:NCBI gene;Acc:101157378])

HSP 1 Score: 418.313 bits (1074), Expect = 2.713e-143
Identity = 206/270 (76.30%), Postives = 231/270 (85.56%), Query Frame = 3 
Query:   72 KNFICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGE-ENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            K    ++L +  VI+       + E  KD  GTVIGIDLGTTYSCVGVFK+GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLTSNPENT+FD KR IGR + D +V+QDIK +PF VI K +KPH+Q+ +G  + + FAPEEISAMVL KMKE AE+YLGK+VTHAVVTVPAYFNDAQRQATKDAGTI+GLNV+RIINEPTAAAIAYGLDKK+GEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+++F
Sbjct:    2 KLLWVVMLVVGAVIA-------EEEDKKDSVGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTSNPENTVFDAKRLIGRSWGDSSVQQDIKYFPFKVIEKKSKPHIQIDIGGGQMKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKDGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 264
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
Match: hspa8b (heat shock cognate 70 kDa protein [Source:NCBI gene;Acc:100125490])

HSP 1 Score: 363.614 bits (932), Expect = 5.169e-122
Identity = 176/239 (73.64%), Postives = 207/239 (86.61%), Query Frame = 3 
Query:  165 GTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP NT+FD KR IGR FDD  V+ D+K++PF VIN N +P V+V+   E + F PEEIS+MVL KMKEIAE+YLGK VT+AVVTVPAYFND+QRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGG DFD R++++F
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVALNPNNTVFDAKRLIGRRFDDSVVQSDMKHWPFTVINDNTRPKVKVEYKGETKTFYPEEISSMVLVKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
Match: ENSORLT00000042552.1 (pep primary_assembly:ASM223467v1:8:710990:713238:-1 gene:ENSORLG00000027683.1 transcript:ENSORLT00000042552.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 350.517 bits (898), Expect = 8.385e-122
Identity = 168/236 (71.19%), Postives = 204/236 (86.44%), Query Frame = 3 
Query:  174 IGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDK-KEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            IGIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP NT+FD KR IGR FD+  V+ D+K++PF V+++  KP +QV    EN+ F PEEIS+MVL KMKEIAE+YLG +V++AV+TVPAYFND+QRQATKDAG I+GLN+ RIINEPTAAAIAYGLDK K GE+N+L+FDLGGGTFDVS+LTI++G+FEV AT GDTHLGG DFD R++++F
Sbjct:    9 IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVALNPSNTVFDAKRLIGRRFDEPVVQADMKHWPFKVVSEGGKPKIQVDYKGENKTFFPEEISSMVLVKMKEIAEAYLGHKVSNAVITVPAYFNDSQRQATKDAGVIAGLNIQRIINEPTAAAIAYGLDKGKSGERNVLIFDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRMVNHF 243
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
Match: hsc70 (heat shock protein 70 cognate [Source:NCBI gene;Acc:100049425])

HSP 1 Score: 361.303 bits (926), Expect = 5.627e-121
Identity = 175/236 (74.15%), Postives = 205/236 (86.86%), Query Frame = 3 
Query:  174 IGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            IGIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP NT+FD KR IGR FDD  V+ D+K++PF VIN N +P VQV+   E + F PEEIS+MVL KMKEIAE+YLGK V +AV+TVPAYFND+QRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGG DFD R++++F
Sbjct:    4 IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDHVVQSDMKHWPFNVINDNTRPKVQVEYKGETKSFYPEEISSMVLTKMKEIAEAYLGKTVNNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGSERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 238
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BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Match: SMESG000068215.1 (SMESG000068215.1)

HSP 1 Score: 553.903 bits (1426), Expect = 0.000e+0
Identity = 270/273 (98.90%), Postives = 271/273 (99.27%), Query Frame = 3 
Query:   60 MMLNKNFICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            MMLNKNFICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+DYF
Sbjct:    1 MMLNKNFICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDYF 273
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BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Match: SMESG000068215.1 (SMESG000068215.1)

HSP 1 Score: 551.592 bits (1420), Expect = 0.000e+0
Identity = 269/272 (98.90%), Postives = 270/272 (99.26%), Query Frame = 3 
Query:   63 MLNKNFICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            MLNKNFICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG DFD RV+DYF
Sbjct:    1 MLNKNFICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDYF 272
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BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Match: SMESG000062699.1 (SMESG000062699.1)

HSP 1 Score: 423.705 bits (1088), Expect = 2.398e-145
Identity = 213/267 (79.78%), Postives = 237/267 (88.76%), Query Frame = 3 
Query:   78 FICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
            FI +++C      YA ++ K  ++ K+DYGTVIGIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLT+NPENT+FDVKR IGR F+D+TV+ D+K++PF VINKNNKP V+V+VG E + FAPEEISAMVLGKMK IAE+YLGK+VTHAVVTVPAYFNDAQRQAT DAG I+GLNVLRIINEPTAAAIAYGLDKK GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGG DFD RV+ YF
Sbjct:    8 FISLLICS----IYAADDDKKEKTKKEDYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYF 270
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BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Match: SMESG000061528.1 (SMESG000061528.1)

HSP 1 Score: 403.29 bits (1035), Expect = 2.519e-137
Identity = 203/278 (73.02%), Postives = 229/278 (82.37%), Query Frame = 3 
Query:   60 MMLNKNFICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKK----EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYFS 881
            M  + +F+ ++LC    I    EN+K+++    DYGTVIGIDLGTTYSCVG+FK GRVEII NDQGNRITPSY+AFTQ+ ERLIGD+AKNQLT+NP NTIFDVKR IGR + D +V++DI +YPF VIN +NKPH+ V +  E + F PEEISAMVLGKMK IAE YLGK+VTHAVVTVPAYFNDAQRQATK+AG I+GL VLRIINEPTAAAIAYGLDKK      E  ILVFDLGGGTFDVSLLTID GVFEVVATNGDTHLGG DFD RVIDYFS
Sbjct:    1 MYYSTSFL-LLLCTAGFIHSDKENEKETKDKILDYGTVIGIDLGTTYSCVGIFKEGRVEIIPNDQGNRITPSYIAFTQDGERLIGDSAKNQLTTNPVNTIFDVKRLIGREWTDSSVQKDITHYPFKVINVDNKPHISVNIKGEEKSFQPEEISAMVLGKMKTIAEEYLGKKVTHAVVTVPAYFNDAQRQATKNAGIIAGLIVLRIINEPTAAAIAYGLDKKAKSEPKEHQILVFDLGGGTFDVSLLTIDQGVFEVVATNGDTHLGGEDFDQRVIDYFS 277
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BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Match: SMESG000081110.1 (SMESG000081110.1)

HSP 1 Score: 354.755 bits (909), Expect = 4.040e-119
Identity = 173/236 (73.31%), Postives = 199/236 (84.32%), Query Frame = 3 
Query:  171 VIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGG*DFD*RVIDYF 878
             IGIDLGTTYSCV VF++G+VEIIANDQGNR TPSYVAFT ++ERLIGDAAKNQ+  NP NT+FD KR IGR FDD  V++D+K +PF VIN  +KP +QV+   E + F PEEIS+MVL KMKE AESYLG +VT AVVTVPAYFND QRQATKDAG I+GLNVLRIINEPTAAAIAYGLDKK  EKNIL+FDLGGGTFDVS+L+I+ G+FEV AT GDTHLGG DFD R++ +F
Sbjct:    5 AIGIDLGTTYSCVAVFQNGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPSNTVFDAKRLIGRKFDDPVVQKDMKLWPFKVINAGSKPKIQVEYKGETKSFFPEEISSMVLTKMKETAESYLGGKVTDAVVTVPAYFNDGQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKKGKEKNILIFDLGGGTFDVSVLSIEEGIFEVKATAGDTHLGGEDFDNRMVQHF 239
The following BLAST results are available for this feature:
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HSPA58.533e-14180.65heat shock protein family A (Hsp70) member 5 [Sour... [more]
HSPA81.057e-12272.38heat shock protein family A (Hsp70) member 8 [Sour... [more]
HSPA84.797e-12172.38heat shock protein family A (Hsp70) member 8 [Sour... [more]
HSPA84.797e-12172.38heat shock protein family A (Hsp70) member 8 [Sour... [more]
HSPA84.797e-12172.38heat shock protein family A (Hsp70) member 8 [Sour... [more]
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hsp-39.787e-13881.25Heat shock 70 kDa protein C [Source:UniProtKB/Swi... [more]
hsp-39.787e-13881.25Heat shock 70 kDa protein C [Source:UniProtKB/Swi... [more]
hsp-39.787e-13881.25Heat shock 70 kDa protein C [Source:UniProtKB/Swi... [more]
hsp-39.787e-13881.25Heat shock 70 kDa protein C [Source:UniProtKB/Swi... [more]
hsp-39.787e-13881.25Heat shock 70 kDa protein C [Source:UniProtKB/Swi... [more]
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Hsc70-31.012e-13881.51gene:FBgn0001218 transcript:FBtr0073610[more]
Hsc70-31.012e-13881.51gene:FBgn0001218 transcript:FBtr0345166[more]
Hsc70-31.012e-13881.51gene:FBgn0001218 transcript:FBtr0073609[more]
Hsc70-31.012e-13881.51gene:FBgn0001218 transcript:FBtr0073611[more]
Hsc70-31.012e-13881.51gene:FBgn0001218 transcript:FBtr0073608[more]
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hspa53.171e-14276.40heat shock protein 5 [Source:NCBI gene;Acc:378848][more]
hspa88.732e-12273.22heat shock protein 8 [Source:NCBI gene;Acc:573376][more]
hspa81.352e-12173.22heat shock protein 8 [Source:NCBI gene;Acc:573376][more]
hspa81.352e-12173.22heat shock protein 8 [Source:NCBI gene;Acc:573376][more]
hspa81.352e-12173.22heat shock protein 8 [Source:NCBI gene;Acc:573376][more]
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nsg12.294e-14474.63neuronal vesicle trafficking associated 1 [Source:... [more]
nsg16.907e-14474.63neuronal vesicle trafficking associated 1 [Source:... [more]
nsg16.048e-14374.63neuronal vesicle trafficking associated 1 [Source:... [more]
nsg16.942e-14375.84neuronal vesicle trafficking associated 1 [Source:... [more]
nsg11.394e-14280.97neuronal vesicle trafficking associated 1 [Source:... [more]
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Hspa55.412e-14180.00heat shock protein 5 [Source:MGI Symbol;Acc:MGI:95... [more]
Hspa55.412e-14180.00heat shock protein 5 [Source:MGI Symbol;Acc:MGI:95... [more]
Hspa83.329e-12172.38heat shock protein 8 [Source:MGI Symbol;Acc:MGI:10... [more]
Hspa1a1.142e-11972.69heat shock protein 1A [Source:MGI Symbol;Acc:MGI:9... [more]
Hspa1b1.336e-11972.69heat shock protein 1B [Source:MGI Symbol;Acc:MGI:9... [more]
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BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q16956|BIP_APLCA1.392e-14476.40Endoplasmic reticulum chaperone BiP OS=Aplysia cal... [more]
sp|Q90593|BIP_CHICK3.604e-14281.20Endoplasmic reticulum chaperone BiP OS=Gallus gall... [more]
sp|Q24895|BIP_ECHMU4.874e-14278.33Endoplasmic reticulum chaperone BiP OS=Echinococcu... [more]
sp|Q0VCX2|BIP_BOVIN1.997e-14080.40Endoplasmic reticulum chaperone BiP OS=Bos taurus ... [more]
sp|Q3S4T7|BIP_ICTTR3.677e-14080.65Endoplasmic reticulum chaperone BiP OS=Ictidomys t... [more]
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BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8HNI71.500e-14876.24Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267GFX26.728e-14876.24Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A430QQ451.921e-14777.26Heat shock 70kDa protein 5 (Fragment) OS=Schistoso... [more]
A0A1I8H5I12.268e-14775.09Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A095CGL81.461e-14679.1078 kDa glucose-regulated protein (Fragment) OS=Sch... [more]
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hspa55.797e-14274.37heat shock protein family A (Hsp70) member 5 [Sour... [more]
hspa8b9.186e-12273.64heat shock cognate 70 kDa protein-like [Source:NCB... [more]
hspa83.823e-12173.64heat shock cognate 71 kDa protein [Source:NCBI gen... [more]
ENSAMXT00000037064.12.826e-12071.97heat shock 70 kDa protein [Source:NCBI gene;Acc:11... [more]
ENSAMXT00000055474.15.498e-12071.97pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
hspa52.142e-14281.45heat shock protein 5 [Source:NCBI gene;Acc:378848][more]
hspa96.762e-8555.88heat shock protein 9 [Source:ZFIN;Acc:ZDB-GENE-030... [more]
hspa134.445e-5742.08heat shock protein 70 family, member 13 [Source:ZF... [more]
hspa142.448e-4333.61heat shock protein 14 [Source:NCBI gene;Acc:565232... [more]
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
KAR21.070e-12372.69ATPase involved in protein import into the ER; als... [more]
SSA11.606e-11569.49ATPase involved in protein folding and NLS-directe... [more]
SSA41.971e-11571.43Heat shock protein that is highly induced upon str... [more]
SSA31.135e-11471.01ATPase involved in protein folding and the respons... [more]
SSA23.003e-11469.07HSP70 family ATP-binding protein; involved in prot... [more]
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO332969.093e-14275.66Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO445302.709e-12072.27Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO372808.435e-11871.19Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO303234.371e-11671.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO477231.146e-8655.20Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hspa52.713e-14376.30heat shock protein family A (Hsp70) member 5 [Sour... [more]
hspa52.713e-14376.30heat shock protein family A (Hsp70) member 5 [Sour... [more]
hspa8b5.169e-12273.64heat shock cognate 70 kDa protein [Source:NCBI gen... [more]
ENSORLT00000042552.18.385e-12271.19pep primary_assembly:ASM223467v1:8:710990:713238:-... [more]
hsc705.627e-12174.15heat shock protein 70 cognate [Source:NCBI gene;Ac... [more]
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BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000068215.10.000e+098.90SMESG000068215.1[more]
SMESG000068215.10.000e+098.90SMESG000068215.1[more]
SMESG000062699.12.398e-14579.78SMESG000062699.1[more]
SMESG000061528.12.519e-13773.02SMESG000061528.1[more]
SMESG000081110.14.040e-11973.31SMESG000081110.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010742 ID=SMED30010742|Name=Endoplasmic reticulum chaperone BiP|organism=Schmidtea mediterranea sexual|type=transcript|length=881bp
CGTAGACCAATAATCTTAAACCACAATAACCAATTACCCTTTTACACGAC
TTTAAAATTATGATGTTAAATAAAAATTTTATTTGTATAATACTATGTAT
TAATGTTGTCATATCTTACGCAACTGAAAACAAAAAAGATAGTGAGAGTC
CAAAGGATGATTACGGTACAGTTATTGGAATAGATCTTGGTACAACATAT
TCATGTGTTGGAGTTTTCAAATCTGGTCGAGTAGAGATAATTGCCAATGA
CCAAGGAAACAGAATCACACCTTCTTACGTTGCATTTACGCAGGAAAGTG
AACGTTTGATTGGAGACGCTGCAAAGAATCAACTGACCTCAAATCCGGAG
AATACAATATTTGATGTGAAAAGATTTATTGGACGAGGATTTGATGATGA
AACTGTGAAGCAGGATATTAAAAATTATCCTTTTTTAGTTATCAATAAAA
ATAATAAACCTCATGTCCAAGTTAAAGTTGGAGAGGAAAATCGAATATTC
GCTCCAGAGGAAATTTCAGCAATGGTCCTTGGGAAAATGAAGGAAATTGC
CGAATCCTATTTAGGTAAAAGGGTTACGCATGCTGTTGTTACTGTTCCAG
CGTATTTTAATGACGCTCAGAGACAAGCAACGAAAGATGCTGGAACTATT
TCTGGTTTAAATGTGCTGCGAATTATTAATGAGCCTACGGCTGCAGCTAT
TGCATATGGTTTGGACAAAAAGGAGGGAGAGAAAAATATTTTAGTTTTCG
ATTTGGGAGGAGGGACATTTGATGTTTCGTTATTGACAATAGATAATGGA
GTTTTCGAAGTGGTAGCTACAAATGGCGATACTCATTTGGGAGGATAAGA
TTTTGACTAAAGAGTTATAGATTATTTTAGC
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protein sequence of SMED30010742-orf-1

>SMED30010742-orf-1 ID=SMED30010742-orf-1|Name=SMED30010742-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=263bp
MMLNKNFICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCV
GVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTI
FDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPE
EISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGL
NVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFE
VVATNGDTHLGG*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0016787hydrolase activity
GO:0000166nucleotide binding
GO:0005524ATP binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000419prepharyngeal region
PLANA:0000429neoblast
Vocabulary: INTERPRO
TermDefinition
IPR043129ATPase_NBD
IPR019651Glutamate_DH_NAD-spec
IPR013126Hsp_70_fam
IPR018181Heat_shock_70_CS
Vocabulary: cellular component
TermDefinition
GO:0005783endoplasmic reticulum
GO:0005788endoplasmic reticulum lumen
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR00301HEATSHOCK70coord: 65..77
score: 80.3
coord: 88..96
score: 63.47
coord: 175..195
score: 91.95
coord: 37..50
score: 82.73
coord: 235..245
score: 79.97
NoneNo IPR availableGENE3DG3DSA:3.30.420.40coord: 228..263
e-value: 1.0E-17
score: 66.0
NoneNo IPR availableGENE3DG3DSA:3.30.30.30coord: 101..151
e-value: 1.2E-23
score: 84.7
NoneNo IPR availablePANTHERPTHR19375:SF380ENDOPLASMIC RETICULUM CHAPERONE BIPcoord: 26..263
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..21
score: 0.754
IPR013126Heat shock protein 70 familyPFAMPF00012HSP70coord: 38..263
e-value: 1.0E-114
score: 384.0
IPR013126Heat shock protein 70 familyPANTHERPTHR19375HEAT SHOCK PROTEIN 70KDAcoord: 26..263
IPR018181Heat shock protein 70, conserved sitePROSITEPS00297HSP70_1coord: 41..48
IPR018181Heat shock protein 70, conserved sitePROSITEPS00329HSP70_2coord: 229..242
IPR043129ATPase, nucleotide binding domainSUPERFAMILYSSF53067Actin-like ATPase domaincoord: 222..263
IPR043129ATPase, nucleotide binding domainSUPERFAMILYSSF53067Actin-like ATPase domaincoord: 36..220