Serine/threonine-protein kinase B-raf

Query:   78 RNKIYCIEASAATHSILPYIKNHVIHTLKSKSHHGDSMKFNLICFNSDVAKWCVSMAPCTSEYITAAADWLRHILPEGSCNFLGAIVSALKEPLNCNICFIVTQHPNQEIKEILDLFAYIGRKIPCHIRLCVLGNTITDEIKNAETVYSQIAKETRGTFAFVQLDSDNQLHIMQSTKNIMNSTDLITIVSSNDEENENIKKF-EVLREEEKKEIFKMSEWALNPNSIDHESYLLGKVYPETHYKPFQFWKRVSASQSFMDCLRNINESNVTKMAHGSGSKLAASVIVGREVLARKYTNGQYYLGYIKDQVNNELFNIVFGPYNWGMGQFVAT--DYQETKLLDLIDLNDAMKRSIIPGDRVLAPDPTSPNKDAFLCRYITGTVLHGSVIRD 1241
            +N  + ++ S     +L  +KN +I TL +K+   DS+ FN+I F+     W   M PC+ + +  A  W+  +      +F  A+  A  +P   ++  + +  P+   + +  L   + R  P H        +I  +  +       ++  TRG+   + L+S   +  +    ++++STD     ++  E+  +   F +V        +  +  W    N     S +  +V   T   P    KRV A                                       R+  +G YYLG I  Q    L+ + F         F+ T    Q T   D+++L  A   SI+PGD VLAP       +  + RY  G V++G   RD
Sbjct:   22 KNISFVLDCSEGMSGVLGAVKNLIIQTLLTKASLRDSL-FNIISFSYKATPWSSRMLPCSPDVVYEALSWIHTLQTSSGRDFHTALALAFSDPACHSVHLVTSSVPDNPTQCLASLSTMVTR--PVHTFYISDKTSINSDTSD---FLQCLSSTTRGSCYIMALNSAGGVEEV----SLLHSTDDSIQKTTYAEDTLHSMDFNQVPYYNCTSCVCSIPYWCSPVNPFSTASCVSARVMQATELFPG---KRVLA---------------------------------------RREMDGFYYLGTIIHQGTGNLYMVEFDKSGMNGNTFMETLNIVQPTCQPDMVNLAIAHGHSIVPGDTVLAP------WEPEMRRYGPGRVIYGVEPRD 354          

Query:  918 AASVIVGREVLARKYTNGQYYLGYIKDQVNNELFNIVFGPYNWGMGQFVAT--DYQETKLLDLIDLNDAMKRSIIPGDRVLAPDPTSPNKDAFLCRYITGTVLHGSVIRD 1241
            A  +  G+ VLAR+  +G YYLG I  Q    L+ + F         F+ T    Q T   D+++L  A   SI+PGD VLAP       +  + RY  G V++G   RD
Sbjct:    3 ATELFPGKRVLARREMDGFYYLGTIIHQGTGNLYMVEFDKSGMNGNTFMETLNIVQPTCQPDMVNLAIAHGHSIVPGDTVLAP------WEPEMRRYGPGRVIYGVEPRD 106          

Query:   27 LISKMSYIETIFETVSSRNKIYCIEASAATHSILPYIKNHVIHTLKSKSHHGDSMKFNLICFNSDVAKWCVSMAPCTSEYITAAADWLRHILPEGSCNFLGAIVSALKEPLNCNICFIVTQH-PNQEIKEILDLFAYIGRKIPCH-IRLCVLGNTITDEIKNAETVYSQIAKETRGTFAFVQLDSDNQL----------HIMQSTKNIMNSTDLITIVSSNDEENENIKKFEVLREEEKKEIFKMSEWALNPNSI-DHESYLLGKVYPETHYKPFQF-----WKRVSASQSFMDCLRNINESNVTKMAHGSGSKLAASVIVGREVLARKYTNGQYYLGYIKDQVNNELFNIVFGPYNWGMGQFVATDYQETKLLDLIDLNDAMKRSIIPGDRVLAPDPTSPNKDAFLCRYITGTVLHGSVIRDYSTARIPVTDTNEGKNIDAPIKHSENLIIEFTSPLSKTEKVVGDKVIYIPEPFFQRLCLESAMPKSAREKLY-KVPNYPLNSLPGYPTSG 1508
            LI K+  I TIF  V  RN  +CI+ S + +  L  +K H++ TL  +++  + M FN+I FNS+V +W   M  CT E +  AA W++ +  +   N  GA+++AL +  NC   +IVT   P+Q  ++ILD     G   P H I LC   NT    I+  E     +A E+ G+F  V L     +          H  +     MN T        N  +N  +    ++  EE   +        +P+ + D   Y     +    + P+++     W R   ++ ++       +  ++ M + S S  A ++++G++VLAR+  +G +Y+G ++ Q+ ++ F + FGP     G++  T YQ+T + D+ID  DA + +I  GDRVLA     P  +    R+  G V+ G                 E + +D P    ++  I  T    KTEKV  D  I+ PE  ++RL LE  MPK AR  L  + P+YP  +L GYPTSG
Sbjct:   36 LIPKIKGIPTIFGEVLERNVTFCIDTSGSMYKGLDVVKEHLVETLLKQANKPNCM-FNIIEFNSEVTQWADKMVKCTPETVAVAATWVKKLSAKTGTNTQGALLTALSD-RNCEAVYIVTDGLPDQHPQDILDQVGLAGHNRPIHCIYLCSEDNTDQVSIEFLED----LAVESFGSFHIVTLTVHGCVERITPIYRADHAHERIIRTMNGT------IHNSTKNCGVSTTLLVDPEESLRLTPRVSLLGHPHPVPDPLGYPYWDTWKNWFFHPYRYYYPHGWSRYRPARGWLKA----QDQMMSSMENSSVSPAAGALLIGKKVLARRIDDGYFYIGTVQSQILSDKFLVAFGPCK--HGKYNETKYQDTFIFDIIDYEDAKRHTIQTGDRVLA--TWEPEGE----RFCPGVVIEG----------------QEKRQVDGP----DDRQITVTFANGKTEKVPMDVAIWTPEQVYERLTLELKMPKEARLSLQNQEPHYPKENLEGYPTSG 504          

Query:   54 TIFETVSSRNKIYCIEASAATHSILPYIKNHVIHTLKSKSHHGD-SMKFNLICFNSDVAKWCVSMAPCTSEYITAAADWLRHILPEGSCNFLGAIVSALKEPLNCNICFIVTQH-PNQEIKEILDLFAYIGRKIPCHIRLCVLGNTITDEIKNAETVYSQIAKETRGTFAFVQLDSDNQLHIMQSTKNIMNSTDLITIVSSNDEENENIKKF--EVLREEEKKEIFKMS-----EWALNP--NSIDHESYLLG--------KVYPETHYKPFQFWKRVSASQSFMDCLRNINESNVTKMAHGSGSKLAASVIVGREVLARKYTNGQYYLGYIKDQVNNELFNIVFGPYNWGMGQFVATDYQETKLLDLIDLNDAMKRSIIPGDRVLAPDPTSPNKDAFLCRYITGTVLHGSVIRDYSTARIPVTDTNEGKNIDAPIKHSENLIIEFTSPLSKTEKVVGDKVIYIPEPFFQRLCLESAMPKSAREKLYK-VPNYPLNSLPGYPTSGSKKIPDDFTFTNPNVL 1556
            T+F  V  +   +CI+ S +    LP +K H++ TL S S   D ++ FNLI FNS V +W   +  CT E +  A  W++ +  +   N   A+++A  +P  C   ++VT   P+Q ++E+LD           H    V G    + +         +A ET G+           LHI+  T  +    + +T +  +D  +E I +     LR   K      S     E  L P  NS+ +    LG           PE +Y P  +W R   ++++++    + +  +  ++  +G     SV+VG+ VLAR+  +G +Y+  ++ Q   E F + FGP     G++  T YQ+T + D++D  DA++ +I+ GDRVLA  P  P  +    RY  G VL G                 E ++ + P    ++L + F++   KTE+V  D  +++P   ++RL LE  MP+ AR+ L   V NYP+ +LPGYP SG    P ++    P+ +
Sbjct:   67 TMFGLVPEKRVTFCIDTSGSMFKSLPVVKEHLMETLHSLSKFRDETVMFNLIEFNSQVTQWADKLVQCTPETVAVAGQWVKALSAKTGTNTQDALLAAFADP-TCQSVYLVTDGPPDQYVEEVLDRVVAASGPRTVHCVYVVTGEAADEAVVE---FLEDLAVETFGS-----------LHIV--TLTLHGCVERVTPIYRSDHAHERIVRTVNNTLRPSVKACSVATSLQIDPEEILAPRLNSLVYPHPYLGYHVSPALVSTMPERYYYP-HYWSRYRPAKAWLEAQDKLVDPRLAGLSPAAG-----SVLVGKRVLARRIEDGYFYMATVQSQNLGEKFLVAFGPCK--HGKYKQTQYQDTYVFDIVDHQDALRHTILTGDRVLA--PWEPEGE----RYAPGIVLSG----------------QEKRHAEGP--EDQDLTVSFSN--GKTERVPRDVAVWLPSSLYERLSLELQMPQEARKTLLSAVDNYPIENLPGYPASGPVGNPPEYPTIEPSFV 536          

Query:   57 IFETVSSRNKIYCIEASAATHSILPYIKNHVIHTL-KSKSHHGDSMKFNLICFNSDVAKWCVSMAPCTSEYITAAADWLRHILPEGSCNFLGAIVSALKEPLNCNICFIVTQH-PNQEIKEILDLFAYIGRKIPCHIRLCV-LGNTITDEIKNAETVYSQIAKETRGTFAFVQLDSDNQLHIMQST-----KNIMNSTD-----------LITIVSSNDEENENIKKFEVLREEEKKEIFKMSEWALNPNSIDHESYLLGKVYPETHYKPFQFWKRVSASQSFMDCL-RNINESNVTKMAHGSGSKLAASVIVGREVLARKYTNGQYYLGYIKDQVNNELFNIVFGPYNWGMGQFVATDYQETKLLDLIDLNDAMKRSIIPGDRVLAPDPTSPNKDAFLCRYITGTVLHGSVIRDYSTARIPVTDTNEGKNIDAPIKHSENLIIEFTSPLSKTEKVVGDKVIYIPEPFFQRLCLESAMPKSAREKLYKVPNYPLNSLPGYPTSGSKKIPDDFTFTNPNVLKSRTLQIDXXXXXXXXXXXXVIEIFDKDDRTGNILTKSDWASGNVIKKSNMHKKNETLVPESIYTISELQLKVKDQLETFKDLPESRMNPEKPFLL 1844
            IF+ V   +  +C++ S + ++ L  +K  ++  L K   H   S  FN++ FNS + +W   M  CT E +  A+ W+  +  +   N + A++ A  +P  C   ++VT   P+Q  +EILD   Y+    P H   CV L     DE  +A      +A ET G+F    + +   +  +         N + STD           + T ++++  E+  +               ++    +NP       Y+   V    +Y P  +W R   ++ ++    + ++E+   +M     S  A ++++G+EVLAR+  +G +Y G ++ Q+    F + FGP     G++  T YQET + D++D  DA +R+++ GD+VL+P    P  D F      G V+ G   R+           +EG +        + + + F++   KTEKV  D  ++IPEP + RL LE  MP+S REKL   PNYPL +LPGYPTSG    P  +      VL+S    +         P  PV  I+ K        T        V+K  ++H     L+P +  T  EL+ +V  QL   K L + R N +   LL
Sbjct:   23 IFDNVVEESVTFCVDTSGSMYNCLHVVKEQLVEALYKHVKHSSGSPLFNIVEFNSQITQWSDKMVKCTPETVAVASKWIDELSAKTGTNTMDALLIAFGDP-ECKAVYLVTDGLPDQNPEEILDHVGYVDNDRPVH---CVYLMGEKADE--SATEFLEDLAIETYGSFFIASITTKGAIEKLTPVFKAEHSNYLKSTDNNLFSKIKQCNVSTTLAADPIESAYLNS-------------RLVSPVINP-------YVFPPVQGYRYYHP-SYWSRYRPAKGWLKMQDKLLDEAQALEM-----SPAAGALLIGKEVLARRNEDGYFYSGSVQSQIYENKFLVAFGPCK--HGKYKDTTYQETMVHDILDYVDAKRRTVVTGDKVLSP--WEPEGDKFG----PGVVIDGFEKRE-----------SEGPD-------DKGITVAFSN--GKTEKVAPDTAVWIPEPMYDRLKLELNMPRSTREKLASQPNYPLENLPGYPTSGPIAYPQKYPKPVSLVLES---DVPLNSFHRYPPYAPVYPIYLKRSEPKKHKT--------VVKSEDVH----ALIPGTQLTTKELEDRVSSQLMEHKLLLDERENEKNGRLL 563          

Query:   54 TIFETVSSRNKIYCIEASAATHSILPYIKNHVIHTLKSKSHHGDSMKFNLICFNSDVAKWCVSMAPCTSEYITAAADWLRHILPEGSCNFLGAIVSALKEPLNCNICFIVTQH-PNQEIKEILDLFAYI--GRKIPCHIRLCVLGNTITDEIKNAETVYSQIAKETRGTFAFVQLDSDNQLHIMQSTKNIMNSTDLITIVSSNDEENENIKKFEVLREEE--KKEIFKMSEW--ALNPNSIDHESYLLGKVYP--------ETHYKPFQFWKRVSASQSFMDCLRNINESNVTKMAHGSGSKLAASVIVGREVLARKYTNGQYYLGYIKDQVNNELFNIVFGPYNWGMGQFVATDYQETKLLDLIDLNDAMKRSIIPGDRVLAPDPTSPNKDAFLCRYITGTVLHGSVIRDYSTARIPVTDTNEGKNIDAPIKHSENLIIEFTSPLSKTEKVVGDKVIYIPEPFFQRLCLESAMPKSAREKLYKVP-NYPLNSLPGYPTSGSKKIPDDFTFTNPNVLKSRTLQID 1580
            T+F  V   +  +CI+ S +    L  +K H++ TL S +       FNLI FNS V +W   M  CT E +  A  W++ +  +   N   A+++AL +PL C   ++VT   P+Q  +++LD    I   R++ C   + + G T  DE   A      +A ET G+F  V L +   +  +       +S + I + + N+    NIK+  +    +   +E   M  +  AL  N   H S L+G V P         + Y+P + W + S  QSFMD L  +             S  A S+++G++V+AR+  +G +Y   ++ Q  +E F + FGP     G+++ T+YQ+T + D++D +DA+  SII GD VLA  P  P+ +    R+  GTV+ G                +E ++ + P   +  L + FT  +  TEKV  +  ++IP   + RL LE  MPK AR+ L     NYP+++LPGYPTSG+   P ++   +P +++S +   D
Sbjct:   79 TMFGRVIENSVTFCIDTSGSMFKYLDVVKQHLMETLLSLAAREYQPMFNLIDFNSQVTRWADKMVKCTPETVAVAEKWIKELQAKTGTNTQDALLTALSDPL-CEAIYLVTDGLPDQYPEDVLDSIVGICGNRRVHC---IYITGET-ADE--TATEFLEDLAVETFGSFHIVTLTTHGCIERITPIYRSDHSHEKI-VQTVNNTLRPNIKRCSIATSLQINPEETLNMVPYTRALLYNWGPHISPLIG-VGPARYYYPYYWSRYRPAKAWLK-SQEQSFMDPLLGL-------------SPAAGSLLIGKKVVARRIDDGFFYRATVQSQNLDEKFLVAFGPCK--HGKYLQTEYQDTYVFDIVDYHDALHHSIITGDNVLA--PWEPDGE----RFAPGTVIEG----------------HEKRHAEGP--DNVQLTVLFTHGI--TEKVPLNTAVWIPPSVYDRLSLELQMPKEARKTLLSCSDNYPIDNLPGYPTSGTLGDPPEYPTADPFIVESNSFLWD 552          

Query:   48 IETIFETVSSRNKIYCIEASAATHSILPYIKNHVIHTLKSKSHHGDSMKFNLICFNSDVAKWCVSMAPCTSEYITAAADWLRHILPEGSCNFLGAIVSALKEPLNCNICFIVTQH-PNQEIKEILDLF--AYIGRKIPCHIRLCVLGNTITDEIKNAETVYSQIAKETRGTFAFVQLDSDNQLHIMQSTKNIMNSTDLITIVSSNDEENENIK-----KFEVLREEEKKEIFKMSEWALNP----NSIDHESYLLGKVYPETHYKPFQFWKRVSASQSFMDCLRNINESNVTKMAHGSGSKLAASVIVGREVLARKYTNGQYYLGYIKDQVNNELFNIVFGPYNWGMGQFVATDYQETKLLDLIDLNDAMKRSIIPGDRVLAPDPTSPNKDAFLCRYITGTVLHGSVIRDYSTARIPVTDTNEGKNIDAPIKHSENLIIEFTSPLSKTEKVVGDKVIYIPEPFFQRLCLESAMPKSAREKLYKVPNYPLNSLPGYPTSGSKKIPDDFTFTNP 1547
            I TIF     +N  +C++ S +    L  +K H++ TL   +       FN+I FNS+V +W   M  C++E +  AA+W++ +  +   N L A+++AL E   C   ++VT   P+Q   +ILD    A  GR I C I LC      T  I+  E     ++ E+ G+F  V L     +  +       ++ + I    +    N   +       +V  EE      ++S +   P    N   H ++    + P  +Y P   W +   ++ ++       ES +  + +   S  A ++++ ++VLAR+  +G +YLG +K Q+  + F + FGP     G++  T YQ+T + DL+D  DA + +I   D+VLAP    P  +    R+  G V+ G                +E +  + P  H   + + F++   +TEK+  D  +++PE  ++RL LE  MP+ ARE L   P+YPL +LPGYPTSG    P  +   +P
Sbjct:    8 IPTIFGETFEKNVTFCVDTSGSMFKGLGVVKEHLVETLLKHARKSQPTSFNIIEFNSEVTQWADKMVKCSAETVEVAAEWVKRLSAKTGTNTLDALLTAL-EDRGCESVYLVTDGLPDQHPVDILDQVTNAVRGRPIHC-IYLCAEDAMDTSAIEFLED----LSVESYGSFHIVSLTQHGCVERVTPIYRADHAHERIVRTINGTLHNHGKQCSVATTLKVDPEESLALTPRVSSFNSYPGFPGNPYGHLAWGHWFMQPHRYYFP-NGWSQYRPARGWLKS----QESMMDHIENSGVSPAAGALLISKKVLARRIDDGYFYLGKVKSQILGDKFLVAFGPSK--PGKYKETTYQDTFVYDLVDYEDAKRHTINTSDKVLAP--WEPQGE----RFGPGVVIEG----------------HEKRGSEGPDDH--QITVTFSN--GRTEKIPSDMALWVPEEVYERLVLELKMPREARETLQTNPHYPLENLPGYPTSGPTAEPRVYEQPHP 480          

Query:   78 RNKIYCIEASAATHSILPYIKNHVIHTLKSKSHHGDSMKFNLICFNSDVAKWCVSMAPCTSEYITAAADWLRHILPEGSCNFLGAIVSALKEPLNCNICFIVTQHPNQEIKEILDLFAYIGRKIPCHIRLCVLGNTITDEIKNAETVYSQIAKETRGTFAFVQ---LDSDNQLHIMQSTKNIMNSTDLITIVSSNDEENENIKKFEVLREEEKKEIFKMSEWALNPNSIDHESYLLGKVYPETHYKPFQ------FWKRVSASQSFMDCLRNINESNVTKMAHGSGSKLAASVIVGREVLARKYTNGQYYLGYIKDQVNNE--LFNIVF 1031
            RN    ++ S A  ++L  +KN ++ TL +K+   +S+ FN+I F+  V  W   M PC  + +  A  W+  +      + L A+ +A  +P  C    +VT                               N++ D  +N  +  S        TF   +   LDSD    +   T     S   + + S +  E     +  +L   E +              I   S+   +     HY P        +W  +    S   C+         ++  G      A    G  VLAR+  +G YYLG I  Q+ +    F + F
Sbjct:   16 RNVTLILDTSEAMTAVLGTVKNLIVQTLLAKASLRNSL-FNIITFSYKVTPWSDHMVPCAPDTVYEALGWIHTLTTSPGKDLLTALTTAFSDPA-CQSVHLVT-------------------------------NSLPDNPENCLSALSTCGTRPVHTFHIAEKQALDSDTLDFLKCLTSATRGSCYRLNLNSGSTAE-----QVALLHSAEHQ--------------IQEPSFSENRCCRALHYNPMHAVCLSPYWGSLRNPFSATPCIS-------ARLMRG------AEFYPGCRVLARREADGFYYLGTIVHQLQDRGGFFMVAF 279          

Query:   54 TIFETVSSRNKIYCIEASAATHSILPYIKNHVIHTLKSKSHHGDSMKFNLICFNSDVAKWCVSMAPCTSEYITAAADWLRHILPEGSCNFLGAIVSALKEPLNCNICFIVTQHPNQEIKEILDLFAYIGRKIPCH-IRLCVLGNTITDEIKNAETVYSQIAKETRGTF 554
            TIF  +  RN ++ ++ S + +  L  ++ H+I  L  ++  G    FN+I FN +V KW   M  CT   ++ A++W+  +    S N +GA++ A  +     I  +    P+Q    I++    + +  P H I LC     +      A      +AKET G+ 
Sbjct:   14 TIFGNILERNVVFLLDTSGSMYHCLDVVREHLIEILFFRATSGRDTMFNVIEFNEEVTKWADRMVQCTPRTVSVASEWINKLQCGTSTNTMGALLEAYDDDGMQAIYLVTDGMPDQRPGIIMENVRKLHKGRPIHAIYLCGAKADVA-----AVEFLEDLAKETNGSL 176          

Query:   39 MSYIETIFETVSSRNKIYCIEASAATHSILPYIKNHVIHTLKSKSHHGDSMKFNLICFNSDVAKWCVSMAPCTSEYITAAADWLRHILPEGSCNFLGAIVSALKEPLNCNICFIVTQHPNQEIKEILDLFAYIGRKIPCHIRLCVLGNTITDEIKNAETVYSQIAKETRGTFAFVQLDSDNQLHIMQSTKNIMNSTDLITIVSSNDEENENIKKFEVLREEEKKEIFKMSEWALNPNSIDHESYLLGKVYPETHYKPFQFWKRVSASQSFMDCLRNINESNVTKMAHGSGSKLAASVIVGREVLARKYTNGQYYLGYIKDQVNNELFNIVFGPYNWGMGQFVATDYQETKLLDLIDLNDAMKRSIIPGDRVLAPDPTSPNKDAFLCRYITGTVLHGSVIRDYSTARIPVTDTNEGKNIDAPIKHSENLIIEFTSPLSKTEKVVGDKVIYIPEPFFQRLCLESAMPKSAREKLYKVPNYPLNSLPGYPTSGSKKIPDDFTFTNPNVLKSRTLQIDXXXXXXXXXXXXVIEIFDKDDRTGNILTKSDWASGNVIKKSNMHKKNETLVPESIYTISELQLKVKDQLETFKDLPESRMNPEKPFLLKGASKKVENDARVAKTVHIKSNEKLLTSPARKVQIDSEPLVEINAPKKSSSLQSLVIQEEYFEDLRKIRESVNEDKDYXXXXXXXXXXXXXXVAEDGVKRILVPQSGQLFQKSFTGKLEVQNSNVVYITDIGEKDKERETVEKIKLQRQ 2291
            MSYIETIFETVSSRNKIYCIEASAATHSILPYIKNHVIHTLKSKSHHGDSMKFNLICFNSDVAKWCVSMAPCTSEYITAAADWLRHILPEGSCNFLGA+VSALKEPLNCNICFIVTQHPNQEIKEILDLFAYIGRKIPCHIRLCVLGNTITDEIKNAETVYSQIAKETRGTFAFVQLDSDNQLHIMQSTKNIMNSTDLITIVSSNDEENENIKKFEVLREEEKKEIFKMSEWALNPNSIDHESYLLGKVYPETHYKPFQFWKRVSASQSFMDCLRNINESNVTKMA GSGSKLAASVIVGREVLARKYTNGQYYLGYIKDQVNNELFNIVFGPYNWGMGQFVATDYQETKLLDLIDLNDAMKRSIIPGDRVLAPDPTSPNKDAFLCRYITGTVLHGSVIRDYSTARIPVTDTNEGKNIDAPIKHSENLIIEFTSPLSKTEKVVGDKVIYIPEPFFQRLCLESAMPKSAREKLYKVPNYPLNSLPGYPTSGSKKIPDDFTFTNPNVLKSRTLQIDYLMPPYCLPLYPVIEIFDKDDRTGNILTKSDWASGNVIKKSNMHKKNETLVPESIYTISELQLKVKDQLETFKDLPESRMNPEKPFLLKGA+KKVENDARVAKTVHIKSNEKLLTSPARKVQIDSEPLVEINAPKKSSSLQSLVIQEEYFEDLRKIRESVNEDKDYSSSSYSRRPSRNRSVAEDGVKRILVPQSGQLFQKSFTGKLEVQNSN VYITDIGEKDKERETVEKIKLQR 
Sbjct:    1 MSYIETIFETVSSRNKIYCIEASAATHSILPYIKNHVIHTLKSKSHHGDSMKFNLICFNSDVAKWCVSMAPCTSEYITAAADWLRHILPEGSCNFLGALVSALKEPLNCNICFIVTQHPNQEIKEILDLFAYIGRKIPCHIRLCVLGNTITDEIKNAETVYSQIAKETRGTFAFVQLDSDNQLHIMQSTKNIMNSTDLITIVSSNDEENENIKKFEVLREEEKKEIFKMSEWALNPNSIDHESYLLGKVYPETHYKPFQFWKRVSASQSFMDCLRNINESNVTKMAQGSGSKLAASVIVGREVLARKYTNGQYYLGYIKDQVNNELFNIVFGPYNWGMGQFVATDYQETKLLDLIDLNDAMKRSIIPGDRVLAPDPTSPNKDAFLCRYITGTVLHGSVIRDYSTARIPVTDTNEGKNIDAPIKHSENLIIEFTSPLSKTEKVVGDKVIYIPEPFFQRLCLESAMPKSAREKLYKVPNYPLNSLPGYPTSGSKKIPDDFTFTNPNVLKSRTLQIDYLMPPYCLPLYPVIEIFDKDDRTGNILTKSDWASGNVIKKSNMHKKNETLVPESIYTISELQLKVKDQLETFKDLPESRMNPEKPFLLKGANKKVENDARVAKTVHIKSNEKLLTSPARKVQIDSEPLVEINAPKKSSSLQSLVIQEEYFEDLRKIRESVNEDKDYSSSSYSRRPSRNRSVAEDGVKRILVPQSGQLFQKSFTGKLEVQNSNAVYITDIGEKDKERETVEKIKLQRH 751          

Query: 2291 IERRLKEEQSRFCQEEMNKDRHVYFQKQKTAARIHKENLIRQSEQEAIDKAQSLKRSVLSEVENKVKSVEPLPPSYDDVDKKRIEGLKNRMAQRNNDMEKRNQDALKYIEKQELSKRNRSDERWWKAQNQMLKEYPA 2701
            IERRLKEEQSRFCQEEMNKDRHVYFQKQKTAARIHKENLIRQSEQEAIDKAQSLKRSVLSEVENKVKSVEPLPPSYDDVDKKRIEGLKNRMAQRNNDMEKRNQDALKYIEKQELSKRNRSDERWWKAQNQMLKEYPA
Sbjct:  755 IERRLKEEQSRFCQEEMNKDRHVYFQKQKTAARIHKENLIRQSEQEAIDKAQSLKRSVLSEVENKVKSVEPLPPSYDDVDKKRIEGLKNRMAQRNNDMEKRNQDALKYIEKQELSKRNRSDERWWKAQNQMLKEYPA 891          

Query:   27 LISKMSYIETIFETVSSRNKIYCIEASAATHSILPYIKNHVIHTLKSKSHHGDSMKFNLICFNSDVAKWCVSMAPCTSEYITAAADWLRHILPEGSCNFLGAIVSALKE-PLNCNICFIVTQ-HPNQEIKEILDLFAYI--GRKIPC 455
            L + +  ++TIF  ++ RN  +C + S + +    + + H++  L       +  KFN+I FNS V ++      C  + I     W+     E   + L AI+ + ++ P   ++ +++T    N+E   +L    +I  GR I C
Sbjct:   22 LRTSLKLVKTIFGEITERNVTFCFDYSGSMYRYFHHFREHLLEALFKMLLSKNGQKFNIILFNSSVHQFASRHVDCVQDNIVDVIRWMNKPSYESKTDILAAIIKSFEDFP---DVVYLITDGFINKERATLLGNLPHISKGRPINC 165          

Query:   27 LISKMSYIETIFETVSSRNKIYCIEASAATHSILPYIKNHVIHTLKSKSHHGDSMKFNLICFNSDVAKWCVSMAPCTSEYITAAADWLRHILPEGSCNFLGAIVSALKEPLNCNICFIVTQ-HPNQEIKEILDLFAYI--GRKIPC 455
            L + +  ++TIF  ++ RN  +C + S + +    + + H++  L       +  KFN+I FNS V ++      C  + I     W+     E   + L AI+ + ++    ++ +++T    N+E   +L    +I  GR I C
Sbjct:   22 LRTSLKLVKTIFGEITERNVTFCFDYSGSMYRYFHHFREHLLEALFKMLLSKNGQKFNIILFNSSVHQFASRHVDCVQDNIVDVIRWMNKPSYESKTDILAAIIKSFED--FPDVVYLITDGFINKERATLLGNLPHISKGRPINC 165          

Query:   27 LISKMSYIETIFETVSSRNKIYCIEASAATHSILPYIKNHVIHTLKSKSHHGDSMKFNLICFNSDVAKWCVSMAPCTSEYITAAADWLRHILPEGSCNFLGAIVSALKEPLNCNICFIVTQ-HPNQEIKEILDLFAYI--GRKIPC 455
            L + +  ++TIF  ++ RN  +C + S + +    + + H++  L       +  KFN+I FNS V ++      C  + I     W+     E   + L AI+ + ++    ++ +++T    N+E   +L    +I  GR I C
Sbjct:   22 LRTSLKLVKTIFGEITERNVTFCFDYSGSMYRYFHHFREHLLEALFKMLLSKNGQKFNIILFNSSVHQFASRHVDCVQDNIVDVIRWMNKPSYESKTDILAAIIKSFED--FPDVVYLITDGFINKERATLLGNLPHISKGRPINC 165          

Query:   57 IFETVSSRNKIYCIEASAATHSILPYIKNHVIHTLKSKSHHGDSMKFNLICFNSDVAKWCVSMAPCTSEYITAAADWLRHILPEGSCNFLGAIVSALKEPLNCNICFIVTQ-HPNQEIKEILDLFAYIGRKIPCHIRLCVLGNTITDEIKNAETVYSQIAKETRGTFAF-------VQLDSDNQLHIMQS-------TKNIMNSTDLITIVSSNDEENENIKKFEVLREEEKKEIFKMSEWALNPN 749
            +F T+        I+ SA+    + ++K+ +   ++ +  H    K N + FN+    W   +   T   + +A  WL  +  +GS N L A+  A+K+  NC   +++T   P+Q  K +L        +I    RL +   +       A T   ++A+ET G F +           ++N+L   +S       ++  +    L  +    DE ++   K EV+R++E+K   K      N N
Sbjct:  562 LFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKS--KINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKD-RNCQGIYLLTDGRPDQPTKTVLS-------QIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLRDECHKLAWKSEVVRKKEQKSTRKTMAPGCNQN 797