PKD2-2

Overview
NamePKD2-2 (AKN21728.1)
Smed IDSMED30010684
Length (bp)2884
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of PKD2-2 (SMED30010684) t-SNE clustered cells

Violin plots show distribution of expression levels for PKD2-2 (SMED30010684) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of PKD2-2 (SMED30010684) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for PKD2-2 (SMED30010684) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30010684

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30010684h1SMcG0006542 SmedASXL_010491SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of PKD2-2 vs. Ensembl Human
Match: PKD2 (polycystin 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9009])

HSP 1 Score: 547.74 bits (1410), Expect = 1.614e-179
Identity = 316/737 (42.88%), Postives = 478/737 (64.86%), Query Frame = 3 
Query:  408 KFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTKQFNGENS-----------------------DYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE--GIDEDERRNQIHNIINSELEKYNYSDTIS 2540
            +  R LR LW T+L E++  NRE Y+K+ +REL+ Y++FL +L I+ +GM+    +YYT+ +  LFLD      EK+ F T+S++ + W++  G  L+GLYW    + Q   D+   ++YEN +LG+PRIRQL+VRN SC IP+  + ++K CY  +S  +ED+  FG  N TAWIYTS + LN S ++ + + Y   G+Y DLSR +  T   + SL +N W+  GTR  FIDF++YN NINLF V+RL+ EFP  GGV  S +F+ +KL+RY++TFD+F+AACE+IFC FI YY+VEE +EIR HKL YF  FWN LD+V++++S+V    +IYRT++V+ L+Q  L ++N FP F+ L+Y Q QFNN  A+ +F  WIK+FK+I+FN+TM+QLS+T++R +KDLFGFA+MFFIIF A+A+L Y +FG+Q++DF    +   TQFRIILGD ++ ++E A+R++GP+YF  F FF+FF+L+NMFLAII DTY+EVK+++A QK E E++D  R      L  L+ K+  + DI +++         KL++DE R +LK +G+ DAEIE++F KYD+DGD+ L  +E + +  +L  E+E ++ D     +     S                           + +  +E+ +L RRVDRME +I  IV K+D ++     +++ K+ + +V+  LL+ +   E  G D +  R Q+  ++  ELE++   D  S
Sbjct:  192 RLVRGLRGLWGTRLMEESSTNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQ-FLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEIHREQMERLVREELERWESDDAAS 923
[Close]
BLAST of PKD2-2 vs. Ensembl Human
Match: PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9011])

HSP 1 Score: 529.25 bits (1362), Expect = 1.617e-174
Identity = 303/710 (42.68%), Postives = 452/710 (63.66%), Query Frame = 3 
Query:  300 MDNEPTAMEDQHQIENVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDT-DLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEI---ESVFVKYDKDGDRTLNLNEQXXX--------XXXXXXXXXXXXXXXXXTKQFNGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDK 2393
            +  +P   ED+ Q E  Y+TQ          + C     + +R LW T LTE+T ENRELYIKTT+REL++Y+VFL  + ++ +GM     +YYTK +  LFL     D   SF  +S++++ W +  GP L+ LYW +WYN Q +   +   +YYEN +LG+PR+RQLKVRN+SC + + F+ D+  CY  +S + E++  FG  N TAW Y S + L    ++   + Y  GG+Y DL  ++  + + LR+L E  W+  GTRV+FIDF++YN NINLF V+RL+ EFP  GG   S + R VKL+RY+S +D+FI  CEVIFC+FI YY+VEE +E+  H+L Y    WN LD+VVI++S+V   F I+RT  V +L+  LL   N +  F+FL++ Q Q+NN  A+NLF AWIKIFKYISFNKTMTQLSSTL R +KD+ GFAVMFFI+FFA+A+LGY +FG+Q+E+F   IK   TQFRIILGDFDY  +++A+RI+GP YF+ + FFVFFVL+NMFLAII DTY+EVK E+A QK+E +++D  +      L  L+ +++++ D+Q  +       ++++ ++++ N L+  G+A+ EI    + F K+D+DG+R L+  EQ+ +               ++L    +   +  +G  +      +  +E+ +L RRV ++E  +  +V ++D +      L++
Sbjct:   46 LQPQPKKPEDEPQ-ETAYRTQV---------SSCCLHICQGIRGLWGTTLTENTAENRELYIKTTLRELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTP-SDTGVSFQAISSMADFWDFAQGPLLDSLYWTKWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFREDILSCYDVYSPDKEEQLPFGPFNGTAWTYHSQDELGGFSHWGRLTSYSGGGYYLDLPGSRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTVKLIRYVSNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKERVSDVQKVLQGG----EQEIQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVALNTEIEKLGRSIVSSPQGKSGPEAARAGGWVSGEEFYMLTRRVLQLETVLEGVVSQIDAVGSKLKMLER 740
[Close]
BLAST of PKD2-2 vs. Ensembl Human
Match: PKD2L2 (polycystin 2 like 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9012])

HSP 1 Score: 427.172 bits (1097), Expect = 1.002e-137
Identity = 237/513 (46.20%), Postives = 356/513 (69.40%), Query Frame = 3 
Query:  471 RELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITD--DTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKN-EFEMADYFRNTARNVLQLLQFKQQK 1997
            +E+ I TT++EL++Y +FL  L I+ FGM++   +Y  K + +LFLD     +E++ F ++ +I++ W+++ GP L GLYWD WYN Q + +  ++  +YYEN +LG+PR+RQLKVRNN+C++   FQ  M  CY +++S NED +NFGL  +T W Y++  + NS  ++     Y +GG+   LS++K+ T      L  NSW+T GTRVIFIDF+LYN N+NLF ++RL+ EFP  GG+ TS +F  VKLLRY+S +DYFIA+CE+ FC+F+  +  +E  +I++ K AYF   WNWL+++++++  V   F+ Y    +  L+  LL +  ++  F FL+     +NN +AI +F AWIKIFK+ISFNKTM+QLSSTL+R  KD+ GFA+MFFIIFFA+A+LG+ +FGSQ++DF     S   QFRI+LGDF++  ++ A+ I+GP+YFI F FFVFFVL+NMFLAII DTY+EVKA+ +  +  +FE+    + + +NVL+  + K+ +
Sbjct:   21 KEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYSTSNT-NSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRLKKAQ 532
[Close]
BLAST of PKD2-2 vs. Ensembl Human
Match: PKD2L2 (polycystin 2 like 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9012])

HSP 1 Score: 427.557 bits (1098), Expect = 1.097e-137
Identity = 237/513 (46.20%), Postives = 356/513 (69.40%), Query Frame = 3 
Query:  471 RELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITD--DTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKN-EFEMADYFRNTARNVLQLLQFKQQK 1997
            +E+ I TT++EL++Y +FL  L I+ FGM++   +Y  K + +LFLD     +E++ F ++ +I++ W+++ GP L GLYWD WYN Q + +  ++  +YYEN +LG+PR+RQLKVRNN+C++   FQ  M  CY +++S NED +NFGL  +T W Y++  + NS  ++     Y +GG+   LS++K+ T      L  NSW+T GTRVIFIDF+LYN N+NLF ++RL+ EFP  GG+ TS +F  VKLLRY+S +DYFIA+CE+ FC+F+  +  +E  +I++ K AYF   WNWL+++++++  V   F+ Y    +  L+  LL +  ++  F FL+     +NN +AI +F AWIKIFK+ISFNKTM+QLSSTL+R  KD+ GFA+MFFIIFFA+A+LG+ +FGSQ++DF     S   QFRI+LGDF++  ++ A+ I+GP+YFI F FFVFFVL+NMFLAII DTY+EVKA+ +  +  +FE+    + + +NVL+  + K+ +
Sbjct:   21 KEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYSTSNT-NSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRLKKAQ 532
[Close]
BLAST of PKD2-2 vs. Ensembl Human
Match: PKD2L2 (polycystin 2 like 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9012])

HSP 1 Score: 407.142 bits (1045), Expect = 3.354e-130
Identity = 231/513 (45.03%), Postives = 347/513 (67.64%), Query Frame = 3 
Query:  471 RELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITD--DTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKN-EFEMADYFRNTARNVLQLLQFKQQK 1997
            +E+ I TT++EL++Y +FL  L I+ FGM++   +Y  K + +LFLD     +E++ F ++ +I++ W+++ GP L GLYWD WYN Q + +  ++  +YYEN +LG+PR+RQLKVRNN+C++   FQ  M  CY +++S NED +NFGL  +T W Y++  + NS  ++     Y +GG+   LS++K+ T      L  NSW+T GTRVIFIDF+LYN N+NLF ++RL+ EFP  GG+ TS +F  VKLLRY+S +DYFIA+CE+ FC+F+  +  +E  +I++ K AYF   WNWL+++++++                        +  ++  F FL+     +NN +AI +F AWIKIFK+ISFNKTM+QLSSTL+R  KD+ GFA+MFFIIFFA+A+LG+ +FGSQ++DF     S   QFRI+LGDF++  ++ A+ I+GP+YFI F FFVFFVL+NMFLAII DTY+EVKA+ +  +  +FE+    + + +NVL+  + K+ +
Sbjct:   21 KEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYSTSNT-NSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLL----------------------KSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRLKKAQ 510
[Close]
BLAST of PKD2-2 vs. Ensembl Celegans
Match: pkd-2 (Polycystin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9U1S7])

HSP 1 Score: 341.273 bits (874), Expect = 2.668e-104
Identity = 240/686 (34.99%), Postives = 377/686 (54.96%), Query Frame = 3 
Query:  483 IKTTVR---ELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQ-MLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTKQFNGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKV-----ISSLLEALNNTEGIDEDERRNQIHNIINSELE 2513
            IK T R   E+  Y VFL +L+ +AF      ++YY+K +  LF+         +F + +++ N+W +L    + G+YW    N    TD+ +++YYEN++LG PRIR LKV N+SC + K FQ ++K C++ +  + EDK   G  +  A+IY + + L +       + Y  GGF Q L    +   Q  + +L  N W+  G+R I +DF LYN NINLF V++L+FE P  GGV T+ +     LL Y ++    +   E IFC FI+Y+I EE   I +H+L Y  +FWN +D+V++  S+   I  + RT +    +  ++ N      FD ++  +  + N  A  +F+AW+K+FK+IS NKTM+QLSSTLTRS+KD+ GFAVMF + FFAFA+ GY  FG+QI D+ NL  SA    R+ILGDF++  LES +R  GP +FI + FFV F+L+NMFLAII D+Y EVKAE+A +K+   + D+F N  R +      K+ K  D             +   Y++++  L   GYA+ +I   F +++     T ++ E+            + E   +E  +   +  +Y + + D   Y  L RRVD+M+E++  IV +++ +      ++K ++ Q        +S+LL   N     +   RR  I +I + + E
Sbjct:   67 IKLTARSFMEVGGYAVFLIVLVYVAFAQNSIQSYYYSKVMSDLFVASTGASGAPAFGSCTSMDNIWDWLSQVLIPGIYWTETSNS---TDNENMIYYENRLLGEPRIRMLKVTNDSCTVMKSFQREIKECFANYEEKLEDKTMVGDGSVDAFIYATAKELENLKTVGTIASYGGGGFVQRLPVAGSTEAQSAIATLKANRWIDRGSRAIIVDFALYNANINLFCVVKLLFELPASGGVITTPKLMTYDLLTYQTSGGTRMMIFEGIFCGFILYFIFEELFAIGRHRLHYLTQFWNLVDVVLLGFSVATIILSVNRTKTGVNRVNSVIENGLTNAPFDDVTSSENSYLNIKACVVFVAWVKVFKFISVNKTMSQLSSTLTRSAKDIGGFAVMFAVFFFAFAQFGYLCFGTQIADYSNLYNSAFALLRLILGDFNFSALESCNRFFGPAFFIAYVFFVSFILLNMFLAIINDSYVEVKAELARKKDGEGILDWFMNKVRGLT-----KRGKRPDA----------PGEDATYEDYKLMLYRAGYAEKDINEAFTRFNVT-SMTEHVPEK------------VAEDIADEVARMTEQKRNYMENHRD---YANLNRRVDQMQESVFSIVDRIEGVNATLQTIEKQRVQQQDGGNLMDLSALLT--NQVRNRESAARRPTITSIADKKEE 716
[Close]
BLAST of PKD2-2 vs. Ensembl Celegans
Match: lov-1 (Location of vulva defective 1 [Source:UniProtKB/Swiss-Prot;Acc:Q09624])

HSP 1 Score: 106.686 bits (265), Expect = 5.221e-23
Identity = 115/565 (20.35%), Postives = 249/565 (44.07%), Query Frame = 3 
Query:  465 ENR-----ELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQI---LGIPRIRQLKVRNNS-CEIPKVFQGDMKHCYSEFSSENEDKNNF------------GLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYIST--------------FDYFIAACEVIFCLFXXXXXXXXXXXXRKH-KLAY-----FYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQ-----FNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQ---FKQQKIRDIQ 2012
            ENR     +L+I  T+R+++ +   L I++++ +   D+  ++Y   + T+    + +  + +F ++    + W +        L    WY+G          Y  +++   +GI  IRQ++ + ++ C + K FQG +  C  E +S+NE+K  +            G + S  + Y + E L++     L   Y  GG+   +S  +   + +   L    W+   TR + I+F+ YN  IN FSV++L+ E P  G    ++    V+L++   +              F   I   E++F L+  Y ++      R   K+ Y      +  WN++D++V  +++   +    R  +  + ++   +N        +++  +Q+     F+  +A  +F    K+ + + FN+ +  L++TL  +   +  F + F      F  + Y + G+++  + +L+ +  T    +LG  D   ++   +    V  +L+      +++ +++ II   + E++ +   Q N++E+ D+ +   +  L LL+   F    I D Q
Sbjct: 2663 ENRKMRDEQLFI--TIRDMLCFFASLYIMVMLTYYCKDRHGYWYQLEMSTILNINQKNYGDNTFMSIQHADDFWDWARESLATAL-LASWYDGNPAYGMR--AYMNDKVSRSMGIGTIRQVRTKKSAECTMFKQFQGYINDCGEELTSKNEEKTLYMQAGWTELESENGTDASDEYTYKTSEELSTETVSGLLYSYSGGGYTISMSGTQAEIITLFNKLDSERWIDDHTRAVIIEFSAYNAQINYFSVVQLLVEIPKSGIYLPNSWVESVRLIKSEGSDGTVVKYYEMLYIFFSVLIFVKEIVFYLYGRYKVITTMKPTRNPFKIVYQLALGNFSPWNFMDLIVGALAVASVLAYTIRQRTTNRAMEDFNANNGN----SYINLTEQRNWEIVFSYCLAGAVFFTSCKMIRILRFNRRIGVLAATLDNALGAIVSFGIAFLFFSMTFNSVLYAVLGNKMGGYRSLMATFQTALAGMLGKLDVTSIQPISQ-FAFVVIMLYMIAGSKLVLQLYVTIIMFEFEEIRNDSEKQTNDYEIIDHIKYKTKRRLGLLEPKDFAPVSIADTQ 3217
[Close]
BLAST of PKD2-2 vs. Ensembl Fly
Match: Pkd2 (gene:FBgn0041195 transcript:FBtr0080365)

HSP 1 Score: 202.601 bits (514), Expect = 1.809e-53
Identity = 136/390 (34.87%), Postives = 225/390 (57.69%), Query Frame = 3 
Query:  762 YENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLA-YFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEF 1928
            YEN +LG PR+RQ++VR  SC +   F      CY+ +SS  ED+      +     + +   L+S+  +++ + Y  GG+  +L  +K   ++++  L +  W+  G+R+  ++F L+N N ++F  ++LI E P  GGV      + VK+  + +     +    + + + ++YY + E  EIRK  +  YF    N LD  +++   +  +++I+ +  V  L     S+   + + D L +    + + +AI  F+ WIKIFK+ISFNKT+ Q ++TL R SKDL GF++MF I+F A+A+LG  +FG++  DF N I S LT  R+ILGDF Y  +E A+R++GP+YF+ +   VFF+L+NMFLAII +TY  VK EI   ++  
Sbjct:  430 YENLLLGPPRLRQIRVRKESCYVNDAFIRYFNTCYAAYSSGAEDRKPMHKGSP----FRTMHDLDSTPIWTVLAFYRTGGYTVNLDYDKDRNVKIINDLKDIHWLDRGSRLCLVEFNLFNENTDIFQSIKLIAEIPPTGGVIPQAHLQTVKMYSFFTDRSMLMTVIYIFWYIMVIYYTIYEITEIRKSGIKIYFCSMLNILDCAILLGCYLALVYNIWHSFKVMSLTARAHSDVT-YQSLDVLCFWNIIYVDMMAILAFLVWIKIFKFISFNKTLVQFTTTLKRCSKDLAGFSLMFGIVFLAYAQLGLLLFGTKHPDFRNFITSILTMIRMILGDFQYNLIEQANRVLGPIYFLTYILLVFFILLNMFLAIIMETYNTVKGEITQGRSHL 814
[Close]
BLAST of PKD2-2 vs. Ensembl Fly
Match: brv3 (gene:FBgn0040333 transcript:FBtr0340092)

HSP 1 Score: 61.2326 bits (147), Expect = 4.011e-9
Identity = 65/273 (23.81%), Postives = 114/273 (41.76%), Query Frame = 3 
Query:  486 KTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEI--PKV----FQGDMKHCYSEFSSENE----------DKNNFGLNNSTAWIYTSPESLNS----SGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDY 1244
            K    +L IY  +   LM +     DQ  ++ T+ +  LF+    D        V  ++ ++ ++    +     +   +G       +    ++ +LG+ R+RQL+V N    +  PK     +  D +  Y +    ++           K  F   ++    +    SLNS    +GY SL            L+R+   +++++  L EN W+TL T  +FIDFTLYN ++NLFS+  L  E    GG+    +    KLL  +    Y
Sbjct:  123 KMIAHDLFIYGPYFLCLMCLVLVTRDQTLYHNTRIITDLFMYNHTD--YTGLQEVYFLNQLFDFIESTLVLAFNSNSTESGSPGWAHAE----QSVLLGVMRLRQLRVSNPQVGLGPPKFSDTYYMPDWQLPYRKLHYSDKYWRIYEPWIPIKMGFEFLDALLMNFDHVGSLNSYPELAGYVSL------------LARSAANSMKVIDYLSENHWLTLNTSAVFIDFTLYNVDVNLFSICTLRVEKTPFGGIVPDVQVDSAKLLENVDQMPY 377
[Close]
BLAST of PKD2-2 vs. Ensembl Fly
Match: brv3 (gene:FBgn0040333 transcript:FBtr0300708)

HSP 1 Score: 60.8474 bits (146), Expect = 4.542e-9
Identity = 51/180 (28.33%), Postives = 82/180 (45.56%), Query Frame = 3 
Query:  765 ENQILGIPRIRQLKVRNNSCEI--PKV----FQGDMKHCYSEFSSENE----------DKNNFGLNNSTAWIYTSPESLNS----SGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDY 1244
            ++ +LG+ R+RQL+V N    +  PK     +  D +  Y +    ++           K  F   ++    +    SLNS    +GY SL            L+R+   +++++  L EN W+TL T  +FIDFTLYN ++NLFS+  L  E    GG+    +    KLL  +    Y
Sbjct:  210 QSVLLGVMRLRQLRVSNPQVGLGPPKFSDTYYMPDWQLPYRKLHYSDKYWRIYEPWIPIKMGFEFLDALLMNFDHVGSLNSYPELAGYVSL------------LARSAANSMKVIDYLSENHWLTLNTSAVFIDFTLYNVDVNLFSICTLRVEKTPFGGIVPDVQVDSAKLLENVDQMPY 377
[Close]
BLAST of PKD2-2 vs. Ensembl Zebrafish
Match: pkd2 (polycystic kidney disease 2 [Source:NCBI gene;Acc:432387])

HSP 1 Score: 562.377 bits (1448), Expect = 0.000e+0
Identity = 305/758 (40.24%), Postives = 474/758 (62.53%), Query Frame = 3 
Query:  345 NVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNE-QXXXXXXXXXXXXXXXXXXXXTKQFNGENSDYNKTNIDI----------------------DEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE--GIDEDERRNQIHNIINSELEKYNYSDTIS 2540
             +Y T    E +      C  +    +R LW T+L  ++  NRE+Y+KT +RE+I Y++FL  L II +GM+    +YYTK +  LFLD      E + F ++ST+ + W++  GPFLNG+YW+ WYN + + ++  L+YYEN +LG+PR+RQL+VRN SC + +  + ++  CY+ +S  NEDK  FG  N TAW +    SL  S Y+   S Y  GG+YQDLSR +  +   L+ L  N W+  GTR +F+DF++YN N+NLF ++RL+ EFP  GG   S +F+ V+LLRY+S++DYF+  CEV FCLF++YY+VEE +EIR H+L YF   WN LD++++ +S+   I +I RT++V   +  LL N + +P F+ L+  Q  FNN  AI +F++W+K+FK+I+FNKTM QLS+T++R +KDL GFA+MFFI+F A+A+L Y +FG+Q+ DF        TQFRIILGDFD+ ++E A  ++GP+YF  F FF+F +L+NMFLAII DTY+EVKA++A Q++E E+ D  + +    +  L+ K+  I DI D++  A      KL +DE R +L+ +G++DAEIE++F KYD DGD+ L  +E Q+  +      ++L  +     +  +G +   ++ + +                       +E+ +L RRVDRME +I  IV K+D ++     +++ K+ +  V+  +L+ +   E  G D + +R Q+  ++  ELE++   DT+S
Sbjct:  112 GLYPTPPAQEHRS-----CGKRILEKMRVLWDTRLLGESNSNREMYLKTVLREMITYILFLLTLCIITYGMVSTNMYYYTKVMSQLFLDTPLSSGEPTNFKSLSTMEDFWKFTEGPFLNGMYWELWYNNKSLPENQSLIYYENLLLGVPRLRQLRVRNESCSVHEDLRDEVYDCYNVYSPANEDKAPFGPKNGTAWRFKDESSLGESSYWGQVSTYGGGGYYQDLSRTREKSANQLQELKNNLWLDRGTRAVFLDFSIYNGNVNLFCIVRLLVEFPATGGAVPSWQFQTVRLLRYVSSWDYFVGMCEVSFCLFVLYYLVEEALEIRLHRLRYFKSLWNCLDVLIVALSVPAIIMNICRTSAVSHRLHFLLENHSTYPNFEPLARLQVHFNNLAAIIVFLSWVKLFKFINFNKTMNQLSTTMSRCAKDLMGFAIMFFIVFLAYAQLAYLVFGTQVNDFSTFQACIFTQFRIILGDFDFSEIEEADSVLGPIYFTTFVFFIFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKSYNRAMVKLKLKKSSINDIPDSLQQA----AGKLSFDELRQDLRGKGHSDAEIEAIFAKYDLDGDQELTEHEHQQMRDDLEKEREDLDLEHSSLPRPASGRSFSRSQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKMKRRDVLGRILDGVMEDERMGRDPELQREQMDRLVRDELERWESDDTMS 860
[Close]
BLAST of PKD2-2 vs. Ensembl Zebrafish
Match: pkd2l1 (polycystic kidney disease 2-like 1 [Source:ZFIN;Acc:ZDB-GENE-030616-558])

HSP 1 Score: 545.428 bits (1404), Expect = 0.000e+0
Identity = 321/756 (42.46%), Postives = 493/756 (65.21%), Query Frame = 3 
Query:  330 QHQIENVYKTQ--AVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITD-DTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTKQFNGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEGIDEDERRNQIHNIINSELEKYNYSDTISIGNVSSASRP-GTARS 2585
               +EN Y  Q  A T   +   +GC   F R ++ LW T L +DT EN EL +K  ++EL+IY+VFL  L ++ +GM    T+YYTKA+  LF++    +   SF+++  +++VW Y+ GP L+ LYW +WYN + + + +   +YYEN +LG+PR+RQLKV+ NSC++P  F+ ++  C+  ++ + ED   FGL N TAW Y S + +  S ++ L + Y   GFYQDL+  +  +  +L  L EN W+  GTRV+FIDFT YN NINLF V+RL+ EFP  GG   S + R VKL+RY++T+DYFI  CE++FC+FI+YYIVEE +E R HKL++F   WN LDIVVI++++V  +F  +RT  V  L+  LL   + +  F+FL++ Q Q+NN  A+NLF AWIKIFKYISFNKTMTQL+STL R + D+FGFA+MFFI+FFA+A+LGY +FG+++E F    K   TQFRIILGDFDY  ++ A+R++GP+YF  + FFVFFVL+NMFLAII DTY+EVK+E+A+QK+EF++AD  + +       L+ K++KI D+Q A+     +   +L++ ++RN LK  G++D EI + F K+D+DG++TL+  EQ+N++ EL  +++ +  ++ + +  + E ++ ++  +  ++Y  L  +V ++E ++S I+ KLD +++      KM++      S  ++   N     +DE R      I+  LE+      ++ G   S + P G+AR+
Sbjct:   36 HSPLENPYLNQDKARTMPNEDKKSGCCSFFFRAIKGLWGTALRKDTKENPELNVKANLKELLIYIVFLVDLCLLTYGMTSSATYYYTKAMTDLFVNLPGSNG-MSFSSIGCMNDVWTYMEGPLLDNLYWTKWYNDEPLENGNQSFIYYENLLLGVPRVRQLKVKQNSCKVPTDFKKEISDCFDVYNIKKEDDGAFGLINGTAWQYHSEKEIKGSSHWGLLTTYSGAGFYQDLTTTRDESAALLEDLRENLWLDRGTRVLFIDFTAYNANINLFCVIRLVVEFPATGGAIPSYQIRTVKLIRYVTTWDYFIIGCEIVFCVFILYYIVEEILEFRIHKLSHFTSIWNILDIVVILLAVVAIVFSAFRTIKVDGLLGNLLKQPDIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLTSTLARCALDIFGFAIMFFIVFFAYAQLGYLLFGTEVETFSTFNKCIFTQFRIILGDFDYDAIDRANRVLGPIYFFSYVFFVFFVLLNMFLAIINDTYSEVKSELASQKDEFQIADLIKQSYAKTFMKLKLKKEKISDVQKAL----DSGASELEFKDFRNALKEMGHSDREISAAFSKFDQDGNQTLDKQEQENMKQELEEKRDALSAELRDLEN-SVEPAEEHRNTVPPEDYQRLVHKVSQLENSVSAIMSKLDFVME------KMRLQTFNTESRDMDKQTNR----DDESRPASGGNIHVNLER-----VLAQGPSWSLTGPMGSARN 770
[Close]
BLAST of PKD2-2 vs. Ensembl Zebrafish
Match: pkd1l2a (polycystic kidney disease 1 like 2a [Source:ZFIN;Acc:ZDB-GENE-050208-89])

HSP 1 Score: 171.014 bits (432), Expect = 7.153e-43
Identity = 143/533 (26.83%), Postives = 272/533 (51.03%), Query Frame = 3 
Query:  471 RELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLF---LDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNF--GLNNS----------TAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAIL 2024
            +E  +   +RE++IYV FL +L+++A+G  D   +Y T  ++  F   + E  + K+           ++ +     L  LY    Y G  ITD        ++++G  RIRQ++VR ++C+I    Q  ++ C++ +S E+ED  ++  G N +            W Y +   L ++  +   + Y  GGF  DL  ++    ++L+ LF+N+W+ + TR +F++FT+YN N+NLF ++ LIFE   +G  +  +E + V L +    F  F+ A E I+ +FI+YY+V +   +++ K AYF   WN L++ +II+S       + RT    + I+   +N++ F +F+  +         +A  + +A IK++  +  N  +  ++STL R+  D+ GF V+  I+F A++     ++G ++  +  L+++A T   + LG F+Y ++   + ++G         F+ FV++N+F+++I   + E +    T   E E+ +        V  LL  K +K +   DA +
Sbjct:  609 KEQKVFALIREILIYVGFLWMLLLVAYGQRDPNAYYLTHHIRQSFSTGISETLNHKD-----------IFIWANSSLLRNLYGQ--YPG-FITDG------NSKLVGNARIRQVRVRRDTCKIANPMQYSVRDCHAPYSWESEDMGSYSPGWNQTRNVNGSKTVLKPWYYQTQAKLRANPVWGGLALYKGGGFVVDLGPDQKNASRLLQYLFDNTWLDVYTRAVFVEFTVYNANVNLFCIVTLIFETTGVGTFQYRSEVQAVHLYQSTGGFHVFVMASEAIYYIFILYYMVVQGKLMKQQKWAYFKSKWNLLELAIIILSWSALSVFVKRTILGNRDIEFYQNNKDMFVSFNETATADAVLGYLIAFLVLLATIKLWHLLRLNPKLHMITSTLQRAWTDISGFIVVMTIMFLAYSIACNLMYGWRLNSYRTLLEAAQTIICLQLGIFNYDEVLDYNPVLGAFLIGSCIIFMTFVVLNLFISVILVAFNEEQLH-PTPSEEEEIVELM---LMKVCSLLGIKCKKKQTNADAPM 1117
[Close]
BLAST of PKD2-2 vs. Ensembl Zebrafish
Match: pkd1l2a (polycystic kidney disease 1 like 2a [Source:ZFIN;Acc:ZDB-GENE-050208-89])

HSP 1 Score: 169.088 bits (427), Expect = 5.224e-42
Identity = 143/533 (26.83%), Postives = 272/533 (51.03%), Query Frame = 3 
Query:  471 RELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLF---LDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNF--GLNNS----------TAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAIL 2024
            +E  +   +RE++IYV FL +L+++A+G  D   +Y T  ++  F   + E  + K+           ++ +     L  LY    Y G  ITD        ++++G  RIRQ++VR ++C+I    Q  ++ C++ +S E+ED  ++  G N +            W Y +   L ++  +   + Y  GGF  DL  ++    ++L+ LF+N+W+ + TR +F++FT+YN N+NLF ++ LIFE   +G  +  +E + V L +    F  F+ A E I+ +FI+YY+V +   +++ K AYF   WN L++ +II+S       + RT    + I+   +N++ F +F+  +         +A  + +A IK++  +  N  +  ++STL R+  D+ GF V+  I+F A++     ++G ++  +  L+++A T   + LG F+Y ++   + ++G         F+ FV++N+F+++I   + E +    T   E E+ +        V  LL  K +K +   DA +
Sbjct: 1969 KEQKVFALIREILIYVGFLWMLLLVAYGQRDPNAYYLTHHIRQSFSTGISETLNHKD-----------IFIWANSSLLRNLYGQ--YPG-FITDG------NSKLVGNARIRQVRVRRDTCKIANPMQYSVRDCHAPYSWESEDMGSYSPGWNQTRNVNGSKTVLKPWYYQTQAKLRANPVWGGLALYKGGGFVVDLGPDQKNASRLLQYLFDNTWLDVYTRAVFVEFTVYNANVNLFCIVTLIFETTGVGTFQYRSEVQAVHLYQSTGGFHVFVMASEAIYYIFILYYMVVQGKLMKQQKWAYFKSKWNLLELAIIILSWSALSVFVKRTILGNRDIEFYQNNKDMFVSFNETATADAVLGYLIAFLVLLATIKLWHLLRLNPKLHMITSTLQRAWTDISGFIVVMTIMFLAYSIACNLMYGWRLNSYRTLLEAAQTIICLQLGIFNYDEVLDYNPVLGAFLIGSCIIFMTFVVLNLFISVILVAFNEEQLH-PTPSEEEEIVELM---LMKVCSLLGIKCKKKQTNADAPM 2477
[Close]
BLAST of PKD2-2 vs. Ensembl Zebrafish
Match: pkd1l2b (polycystic kidney disease 1 like 2b [Source:ZFIN;Acc:ZDB-GENE-141222-87])

HSP 1 Score: 162.54 bits (410), Expect = 2.186e-40
Identity = 130/478 (27.20%), Postives = 241/478 (50.42%), Query Frame = 3 
Query:  495 VRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFG--------LNNS----TAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAE 1892
            V E++I++ FL++L+++A+G  D   FY T+ ++  F     D  + +   V   + + + LFG           Y G  ITD        ++++G  RIRQ++V+ ++C++ KV    +  C + +S  NED  ++G        +N S    TAW Y S  +L +   + L + Y  GG+  DL  +K      L+ LF ++W+   TR +F++FT+YN N++LF ++ LI E   +G  +  +  + V L   + +F  F+ A  VI+ LF+VYY+  +   +++ K AYF   WN LD+ +II+S       I +T      IQ    ++NQFP+F   +         +A  + +  +K++  +  +  +  ++S+L R+  D+    V+ FII  A++     IFG ++  +  L  +    F + +G F+Y ++ +++  +G V          FV++++F++II     E
Sbjct:  520 VMEVLIFLGFLSMLLLVAYGQQDPNAFYLTQHIQQSFSKGISDSMKTNDVFVWANTVLLKNLFGQ----------YPG-FITDG------NSKLVGNARIRQVRVKKDTCKVAKVMLHTVSQCNTPYSWGNEDMMSYGPGWEEFNSVNGSEEGITAWQYQSQSTLKALPVWGLTALYRGGGYVMDLGPDKQNATMKLQYLFNSTWLDEYTRAVFVEFTVYNANVDLFCIVTLILESSAVGAFQFRSVLQNVSLYSSVGSFMSFLMASRVIYFLFVVYYMFLQGKLLKRQKWAYFRNKWNLLDMAIIILSWSSLSLFIQKTVQGNIDIQYYQKHKNQFPSFHDTAAVDATLRYVMAFLVLLGCVKLWHLLRLSPKLYVIASSLQRAWDDMSTLTVVIFIILLAYSLACNLIFGWELYTYRTLPDAFTAIFSLQIGIFNYDEVMNSNPALGAVIISSCVLIATFVVLSLFISIILMAVTE 980
[Close]
BLAST of PKD2-2 vs. Ensembl Xenopus
Match: usp33 (ubiquitin specific peptidase 33 [Source:Xenbase;Acc:XB-GENE-1016674])

HSP 1 Score: 565.459 bits (1456), Expect = 0.000e+0
Identity = 319/779 (40.95%), Postives = 479/779 (61.49%), Query Frame = 3 
Query:  369 TEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNE-QXXXXXXXXXXXXXXXXXXXXTKQFNGEN----------------------SDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE--GIDEDERRNQIHNIINSELEKYNYSDTIS-----IGNVSS--------ASRPGTARST 2588
            + EQ     G      R+ R LW T+ TE+    RE Y+K   RELI Y+VFL I+ ++ + M+    FYYTK +  LFLD      E++ F T+ T+ + W++  GP ++GLYWD WYN + + ++   +YYEN +LG+PR+RQL+V+N SC +P+  + ++K CY  +S  NED   FGL N TAW YT  + LN S  + + S Y   G+Y DLSRN+  +   +  L  N W+  GTR +FIDF++YN N+NLF V+RL+ EFP  GG+ TS +F+ VKL+ YIS+F++F+AACE+IFC+FI+YYI+EE +EI  H L YF   WNWLDIV+I +SL      +Y+ +SV+  +   LS+ N FP  + L+Y Q QFN+  A+ +F AW+K+FK+ +FN+TMTQLS+T++R +KD+ GFA+MFFIIF A+A+  Y +FG+QI+DF        TQFRIILGDFD+ ++E A+RI+GP+YF  F FF+FF+L+NMFLAII DTY+EVK ++A QK+E E+ D  +      +  L+ K+  + DI ++I         KL++DE R +LK +G+ DAEIE++F KYD+DGD+ L  NE Q+  +      ++L        +  +G +                         + + +  +E+ +L RRVDRME +I  IV K+D ++     +++ K+ + +V+  LL+ +   E  G D +  R Q+  ++  ELE++   DT+S     +G  S          SRP +++ST
Sbjct:  157 STEQPQELEGAGKLLHRV-RGLWGTRYTEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVSKDERTNFKTLLTMDDFWKFTEGPLMDGLYWDMWYNNRTMAENHSFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPFGLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAMVKLKLKKTTVDDISESIRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEMDRGSLPRPMSGRSFPRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLDGVTEDERLGRDNELHREQMERLVREELERWESDDTVSQMSHRLGTPSGNNGQARSRGSRPPSSQST 930
[Close]
BLAST of PKD2-2 vs. Ensembl Xenopus
Match: usp33 (ubiquitin specific peptidase 33 [Source:Xenbase;Acc:XB-GENE-1016674])

HSP 1 Score: 564.303 bits (1453), Expect = 0.000e+0
Identity = 316/764 (41.36%), Postives = 479/764 (62.70%), Query Frame = 3 
Query:  414 KRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNE-QXXXXXXXXXXXXXXXXXXXXTKQFNGEN----------------------SDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE--GIDEDERRNQIHNIINSELEKYNYSDTIS-----IGNVSS--------ASRPGTARST 2588
            +R  R LW T+ TE+    RE Y+K   RELI Y+VFL I+ ++ + M+    FYYTK +  LFLD      E++ F T+ T+ + W++  GP ++GLYWD WYN + + ++   +YYEN +LG+PR+RQL+V+N SC +P+  + ++K CY  +S  NED   FGL N TAW YT  + LN S  + + S Y   G+Y DLSRN+  +   +  L  N W+  GTR +FIDF++YN N+NLF V+RL+ EFP  GG+ TS +F+ VKL+ YIS+F++F+AACE+IFC+FI+YYI+EE +EI  H L YF   WNWLDIV+I +SL      +Y+ +SV+  +   LS+ N FP  + L+Y Q QFN+  A+ +F AW+K+FK+ +FN+TMTQLS+T++R +KD+ GFA+MFFIIF A+A+  Y +FG+QI+DF        TQFRIILGDFD+ ++E A+RI+GP+YF  F FF+FF+L+NMFLAII DTY+EVK ++A QK+E E+ D  +  ++ +++ L+ K+  + DI ++I         KL++DE R +LK +G+ DAEIE++F KYD+DGD+ L  NE Q+  +      ++L        +  +G +                         + + +  +E+ +L RRVDRME +I  IV K+D ++     +++ K+ + +V+  LL+ +   E  G D +  R Q+  ++  ELE++   DT+S     +G  S          SRP +++ST
Sbjct:   47 RRETRRLWGTRYTEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVSKDERTNFKTLLTMDDFWKFTEGPLMDGLYWDMWYNNRTMAENHSFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPFGLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKVSKAMVK-LKLKKTTVDDISESIRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEMDRGSLPRPMSGRSFPRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLDGVTEDERLGRDNELHREQMERLVREELERWESDDTVSQMSHRLGTPSGNNGQARSRGSRPPSSQST 805
[Close]
BLAST of PKD2-2 vs. Ensembl Xenopus
Match: usp33 (ubiquitin specific peptidase 33 [Source:Xenbase;Acc:XB-GENE-1016674])

HSP 1 Score: 563.918 bits (1452), Expect = 0.000e+0
Identity = 316/770 (41.04%), Postives = 474/770 (61.56%), Query Frame = 3 
Query:  396 GCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNE-QXXXXXXXXXXXXXXXXXXXXTKQFNGEN----------------------SDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE--GIDEDERRNQIHNIINSELEKYNYSDTIS-----IGNVSS--------ASRPGTARST 2588
            G W         LW T+ TE+    RE Y+K   RELI Y+VFL I+ ++ + M+    FYYTK +  LFLD      E++ F T+ T+ + W++  GP ++GLYWD WYN + + ++   +YYEN +LG+PR+RQL+V+N SC +P+  + ++K CY  +S  NED   FGL N TAW YT  + LN S  + + S Y   G+Y DLSRN+  +   +  L  N W+  GTR +FIDF++YN N+NLF V+RL+ EFP  GG+ TS +F+ VKL+ YIS+F++F+AACE+IFC+FI+YYI+EE +EI  H L YF   WNWLDIV+I +SL      +Y+ +SV+  +   LS+ N FP  + L+Y Q QFN+  A+ +F AW+K+FK+ +FN+TMTQLS+T++R +KD+ GFA+MFFIIF A+A+  Y +FG+QI+DF        TQFRIILGDFD+ ++E A+RI+GP+YF  F FF+FF+L+NMFLAII DTY+EVK ++A QK+E E+ D  +      +  L+ K+  + DI ++I         KL++DE R +LK +G+ DAEIE++F KYD+DGD+ L  NE Q+  +      ++L        +  +G +                         + + +  +E+ +L RRVDRME +I  IV K+D ++     +++ K+ + +V+  LL+ +   E  G D +  R Q+  ++  ELE++   DT+S     +G  S          SRP +++ST
Sbjct:  169 GLWIYIFHFFAGLWGTRYTEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVSKDERTNFKTLLTMDDFWKFTEGPLMDGLYWDMWYNNRTMAENHSFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPFGLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAMVKLKLKKTTVDDISESIRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEMDRGSLPRPMSGRSFPRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLDGVTEDERLGRDNELHREQMERLVREELERWESDDTVSQMSHRLGTPSGNNGQARSRGSRPPSSQST 934
[Close]
BLAST of PKD2-2 vs. Ensembl Xenopus
Match: usp33 (ubiquitin specific peptidase 33 [Source:Xenbase;Acc:XB-GENE-1016674])

HSP 1 Score: 561.222 bits (1445), Expect = 0.000e+0
Identity = 314/758 (41.42%), Postives = 472/758 (62.27%), Query Frame = 3 
Query:  432 LWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNE-QXXXXXXXXXXXXXXXXXXXXTKQFNGEN----------------------SDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE--GIDEDERRNQIHNIINSELEKYNYSDTIS-----IGNVSS--------ASRPGTARST 2588
            LW T+ TE+    RE Y+K   RELI Y+VFL I+ ++ + M+    FYYTK +  LFLD      E++ F T+ T+ + W++  GP ++GLYWD WYN + + ++   +YYEN +LG+PR+RQL+V+N SC +P+  + ++K CY  +S  NED   FGL N TAW YT  + LN S  + + S Y   G+Y DLSRN+  +   +  L  N W+  GTR +FIDF++YN N+NLF V+RL+ EFP  GG+ TS +F+ VKL+ YIS+F++F+AACE+IFC+FI+YYI+EE +EI  H L YF   WNWLDIV+I +SL      +Y+ +SV+  +   LS+ N FP  + L+Y Q QFN+  A+ +F AW+K+FK+ +FN+TMTQLS+T++R +KD+ GFA+MFFIIF A+A+  Y +FG+QI+DF        TQFRIILGDFD+ ++E A+RI+GP+YF  F FF+FF+L+NMFLAII DTY+EVK ++A QK+E E+ D  +      +  L+ K+  + DI ++I         KL++DE R +LK +G+ DAEIE++F KYD+DGD+ L  NE Q+  +      ++L        +  +G +                         + + +  +E+ +L RRVDRME +I  IV K+D ++     +++ K+ + +V+  LL+ +   E  G D +  R Q+  ++  ELE++   DT+S     +G  S          SRP +++ST
Sbjct:   15 LWGTRYTEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVSKDERTNFKTLLTMDDFWKFTEGPLMDGLYWDMWYNNRTMAENHSFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPFGLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAMVKLKLKKTTVDDISESIRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEMDRGSLPRPMSGRSFPRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLDGVTEDERLGRDNELHREQMERLVREELERWESDDTVSQMSHRLGTPSGNNGQARSRGSRPPSSQST 768
[Close]
BLAST of PKD2-2 vs. Ensembl Xenopus
Match: usp33 (ubiquitin specific peptidase 33 [Source:Xenbase;Acc:XB-GENE-1016674])

HSP 1 Score: 559.681 bits (1441), Expect = 0.000e+0
Identity = 313/749 (41.79%), Postives = 469/749 (62.62%), Query Frame = 3 
Query:  432 LWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNE-QXXXXXXXXXXXXXXXXXXXXTKQFNGEN----------------------SDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE--GIDEDERRNQIHNIINSELEKYNYSDTIS-----IGNVSSASRPGTARS 2585
            LW T+ TE+    RE Y+K   RELI Y+VFL I+ ++ + M+    FYYTK +  LFLD      E++ F T+ T+ + W++  GP ++GLYWD WYN + + ++   +YYEN +LG+PR+RQL+V+N SC +P+  + ++K CY  +S  NED   FGL N TAW YT  + LN S  + + S Y   G+Y DLSRN+  +   +  L  N W+  GTR +FIDF++YN N+NLF V+RL+ EFP  GG+ TS +F+ VKL+ YIS+F++F+AACE+IFC+FI+YYI+EE +EI  H L YF   WNWLDIV+I +SL      +Y+ +SV+  +   LS+ N FP  + L+Y Q QFN+  A+ +F AW+K+FK+ +FN+TMTQLS+T++R +KD+ GFA+MFFIIF A+A+  Y +FG+QI+DF        TQFRIILGDFD+ ++E A+RI+GP+YF  F FF+FF+L+NMFLAII DTY+EVK ++A QK+E E+ D  +      +  L+ K+  + DI ++I         KL++DE R +LK +G+ DAEIE++F KYD+DGD+ L  NE Q+  +      ++L        +  +G +                         + + +  +E+ +L RRVDRME +I  IV K+D ++     +++ K+ + +V+  LL+ +   E  G D +  R Q+  ++  ELE++   DT+S     +G  S  +  G ARS
Sbjct:  178 LWGTRYTEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVSKDERTNFKTLLTMDDFWKFTEGPLMDGLYWDMWYNNRTMAENHSFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPFGLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAMVKLKLKKTTVDDISESIRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEMDRGSLPRPMSGRSFPRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLDGVTEDERLGRDNELHREQMERLVREELERWESDDTVSQMSHRLGTPSGNN--GQARS 920
[Close]
BLAST of PKD2-2 vs. Ensembl Mouse
Match: Pkd2 (polycystin 2, transient receptor potential cation channel [Source:MGI Symbol;Acc:MGI:1099818])

HSP 1 Score: 548.51 bits (1412), Expect = 4.754e-180
Identity = 307/737 (41.66%), Postives = 472/737 (64.04%), Query Frame = 3 
Query:  408 KFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTKQFNGENS-----------------------DYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE--GIDEDERRNQIHNIINSELEKYNYSDTIS 2540
            +  R LR LW T+L E++  NRE Y+K+ +REL+ Y+ FL +L I+ +GM+    +YYT+ L  LF+D      EK+ F T+S++ + W++  G FL+GLYW    +     D+   ++YEN +LG+PR+RQL+VRN SC IP+  + ++K CY  +S  +ED+  FG  N TAW+YTS + LN S ++ + + Y   G+Y DLSR +  T   L  L  N W+  GTR  FIDF++YN NINLF V+RL+ EFP  GGV  S +F+ VKL+RY++ FD+F+AACE+IFC FI+YY+VEE +EIR H+L+YF  FWN LD+V++++S+V  + +IYR ++ + L+Q  L ++N FP F+ ++Y Q QFNN  A+ +F+ WIK+FK+I+FN+TM+QLS+T++R +KDLFGF +MF IIF A+A+L Y +FG+Q++DF    +   TQFRIILGD ++ ++E A+R++GP+YF  F FF+FF+L+NMFLAII D+Y+EVK+++A QK E E++D  R   +  L  L+ K    R+  DAI  +      KL++DE R +LK +G+ DAEIE++F KYD+DGD+ L   E + +  +L  E+E ++ +     +     S                           + +  +E+ +L RRVDRME +I  IV K+D ++     +++ K+ + +V+  LL+ +      G D +  R Q+  ++  ELE++   D  S
Sbjct:  190 RLVRGLRGLWGTRLMEESNANREKYLKSVLRELVTYLFFLVVLCILTYGMMSSNVYYYTRTLSQLFIDTPVSKTEKTNFKTLSSMEDFWKFTEGSFLDGLYWKAQTSNHTQADNRSFIFYENLLLGVPRLRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWMYTSEKELNGSSHWGIIASYSGAGYYLDLSRTREETAAQLAGLRRNFWLDRGTRAAFIDFSVYNANINLFCVVRLLAEFPATGGVVPSWQFQPVKLIRYVTAFDFFLAACEIIFCFFIIYYVVEEILEIRIHRLSYFRSFWNCLDVVIVVLSVVAMVINIYRMSNAEGLLQ-FLEDQNSFPNFEHVAYWQIQFNNISAVMVFLVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFTIMFSIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPLYFTTFVFFMFFILLNMFLAIINDSYSEVKSDLAQQKAEMELSDLIRKGCQKALVKLKLK----RNTVDAISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEREHQQMRDDLEKEREDLDLEHSSLPRPMSSRSFPRSLDDSEEEDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDARLGRDSEIHREQMERLVREELERWESDDAAS 921
[Close]
BLAST of PKD2-2 vs. Ensembl Mouse
Match: Pkd2l1 (polycystic kidney disease 2-like 1 [Source:MGI Symbol;Acc:MGI:1352448])

HSP 1 Score: 522.702 bits (1345), Expect = 1.152e-172
Identity = 292/681 (42.88%), Postives = 448/681 (65.79%), Query Frame = 3 
Query:  378 QKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDT-DLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTKQFNGEN--------SDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDK 2393
            Q+   + C     R +R LW T LTE+T ENRELY+KTT+REL++Y+VFL  + ++ +GM     +YYTK +  LFL     D   SF T+S++S+ W +  GP L+ LYW +WYN Q +   +   +YYEN +LG PR+RQL+VRN+SC + + F+ D+ +CY  +S + ED+  FG  N TAW Y S   L  S ++   + Y  GG+Y DL  ++  + + L+ L E  W+  GTRV+FIDF++YN NINLF ++RL+ EFP  GG   S + R VKL+RY++ +D+FI  CEV+FC+FI YY+VEE +EI  H+L Y    WN LD+VVI++S+V   F I+RT  V +L+  LL   + +  F+FL++ Q Q+NN  A+NLF AWIKIFKYISFNKTMTQLSSTL R +KD+ GFA+MFFI+FFA+A+LGY +FG+Q+E+F   +K   TQFRIILGDFDY  +++A+RI+GPVYF+ + FFVFFVL+NMFLAII DTY+EVK E+A QK++ +++D+ + +    L  L+ +++++ D+Q  +       + ++ ++++ + L+  G+ + EI + F ++D+DGD  L+  EQ+ +   L  E+  +  +IE   +  G +        +   ++ +  +E+++L RRV +++  +  +V ++D +      L++
Sbjct:   62 QRTLVSSCCLHICRSIRGLWGTTLTENTAENRELYVKTTLRELVVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTP-SDSGVSFQTISSMSDFWDFAQGPLLDSLYWTKWYNNQSLGRGSHSFIYYENLLLGAPRLRQLRVRNDSCVVHEDFREDILNCYDVYSPDKEDQLPFGPQNGTAWTYHSQNELGGSSHWGRLTSYSGGGYYLDLPGSRQASAEALQGLQEGLWLDRGTRVVFIDFSVYNANINLFCILRLVVEFPATGGTIPSWQIRTVKLIRYVNNWDFFIVGCEVVFCVFIFYYVVEEILEIHLHRLRYLSSVWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPDTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDYNAIDNANRILGPVYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDQLQLSDFLKQSYNKTLLRLRLRKERVSDVQKVLKGG----EPEIQFEDFTSTLRELGHEEHEITAAFTRFDQDGDHILDEEEQEQMRQGLEEERVTLNAEIENLGRSVGHSPPGELGAEAARGQSWVSGEEFDMLTRRVLQLQCVLEGVVSQIDAVGSKLKMLER 737
[Close]
BLAST of PKD2-2 vs. Ensembl Mouse
Match: Pkd2l2 (polycystic kidney disease 2-like 2 [Source:MGI Symbol;Acc:MGI:1858231])

HSP 1 Score: 417.157 bits (1071), Expect = 7.062e-134
Identity = 233/514 (45.33%), Postives = 350/514 (68.09%), Query Frame = 3 
Query:  453 EDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKF-DDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDI--TDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIAT-QKNEFEMADYFRNTARNVLQLLQ 1982
             D    RE  + TT+ EL++Y +FL  L I+ FGM++   +Y  K + +LF+D    DD+  SF ++ +I+  W+++ GP ++GLYWD WY  + +    ++  +YYEN +LGIPR+RQL+VRNN+C++   FQ  +  CYS+++ ENED ++FGL  +  W +T P S  +  ++     Y DGG+   LS++K+ T      L  N+W++ GTR +FIDF+LYN N+NLF ++RL+ EFP  GG+ TS +F  VKLLRY+S +DYFIA+CEVIFC+F+  +I++E  ++ + K AYF   WNWL+++++++  +   F  Y       L+  LL N + +P F FL+Y    +NN +AI +F AWIKIFK+ISFN+TM+QLSSTL+R  KD+ GFA+MFFIIF A+A+LG+ +FGSQ++DF     S   QFRI+LGDF++  ++ A+ I+GP+YFI F FFVFFVL+NMFLAII DTY+EVKA+ +  ++ +FE+    + +  NVL+ L+
Sbjct:   15 HDLHYRREAEVNTTLEELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFVDTSLPDDERSSFRSIRSITEFWKFMEGPLIDGLYWDSWYGNKQLYSVKNSSRIYYENVLLGIPRVRQLRVRNNTCKVYPAFQSLVSDCYSKYTVENEDFSDFGLKRNPEWTHT-PSSRTAPWHWGFVGVYRDGGYIVTLSKSKSETKAKFVDLRLNNWISRGTRAVFIDFSLYNANVNLFCIIRLLAEFPATGGLLTSWQFYSVKLLRYVSYYDYFIASCEVIFCIFLFVFIIQELRKVNEFKSAYFRSVWNWLEMLLLLLCFLAVSFYAYCNMQSFLLLGQLLKNTDSYPDFYFLAYWHIYYNNVIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFSAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANWILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRPDFELGKIIQKSCFNVLEKLR 527
[Close]
BLAST of PKD2-2 vs. Ensembl Mouse
Match: Pkd2l2 (polycystic kidney disease 2-like 2 [Source:MGI Symbol;Acc:MGI:1858231])

HSP 1 Score: 417.157 bits (1071), Expect = 7.062e-134
Identity = 233/514 (45.33%), Postives = 350/514 (68.09%), Query Frame = 3 
Query:  453 EDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKF-DDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDI--TDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIAT-QKNEFEMADYFRNTARNVLQLLQ 1982
             D    RE  + TT+ EL++Y +FL  L I+ FGM++   +Y  K + +LF+D    DD+  SF ++ +I+  W+++ GP ++GLYWD WY  + +    ++  +YYEN +LGIPR+RQL+VRNN+C++   FQ  +  CYS+++ ENED ++FGL  +  W +T P S  +  ++     Y DGG+   LS++K+ T      L  N+W++ GTR +FIDF+LYN N+NLF ++RL+ EFP  GG+ TS +F  VKLLRY+S +DYFIA+CEVIFC+F+  +I++E  ++ + K AYF   WNWL+++++++  +   F  Y       L+  LL N + +P F FL+Y    +NN +AI +F AWIKIFK+ISFN+TM+QLSSTL+R  KD+ GFA+MFFIIF A+A+LG+ +FGSQ++DF     S   QFRI+LGDF++  ++ A+ I+GP+YFI F FFVFFVL+NMFLAII DTY+EVKA+ +  ++ +FE+    + +  NVL+ L+
Sbjct:   15 HDLHYRREAEVNTTLEELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFVDTSLPDDERSSFRSIRSITEFWKFMEGPLIDGLYWDSWYGNKQLYSVKNSSRIYYENVLLGIPRVRQLRVRNNTCKVYPAFQSLVSDCYSKYTVENEDFSDFGLKRNPEWTHT-PSSRTAPWHWGFVGVYRDGGYIVTLSKSKSETKAKFVDLRLNNWISRGTRAVFIDFSLYNANVNLFCIIRLLAEFPATGGLLTSWQFYSVKLLRYVSYYDYFIASCEVIFCIFLFVFIIQELRKVNEFKSAYFRSVWNWLEMLLLLLCFLAVSFYAYCNMQSFLLLGQLLKNTDSYPDFYFLAYWHIYYNNVIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFSAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANWILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRPDFELGKIIQKSCFNVLEKLR 527
[Close]
BLAST of PKD2-2 vs. Ensembl Mouse
Match: Pkd1l2 (polycystic kidney disease 1 like 2 [Source:MGI Symbol;Acc:MGI:2664668])

HSP 1 Score: 146.747 bits (369), Expect = 4.034e-35
Identity = 115/477 (24.11%), Postives = 232/477 (48.64%), Query Frame = 3 
Query:  495 VRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFG-------LNNST----AWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAE 1892
            +RE++ Y+ FL +L+++A+G  D   +++ + L+  F         + F+ V      +++     +  LY    ++   +TD        ++++G   IRQ++VR +SC + +  Q  +  C+  +S   ED  ++G        NNS     AW Y S         +   + Y  GG+   L  +     ++L+ LF+NSW+   TR +F++FT+YN N+NLF  + L  E   +G   +    + ++L  +   +  F+ A E+ + LF+ YY+V +   +RK K  YF   WN L++ +I+ S    +  + RT    + +Q    + ++  +F   +         +A  + ++ +K++  +  N  M  ++S L R+  D+ GF  +  I+  A++     +FG ++  ++ L  +A T   + LG F+Y+++     I+G +       F+ FV++N+F+++I   ++E
Sbjct: 1944 IREILAYLAFLWMLLLVAYGQRDPNAYHFHRHLERSF--------SQGFSPVLGFRGFFEWANTTLVKNLYG---HHPGFVTDG------NSKLVGSAHIRQVRVRESSCAVAQQLQDSLDGCHGPYSLGIEDLVDYGEGWNASAYNNSNGFPQAWRYQSQSQRRGYPMWGKLTLYGGGGYVVPLGTDHQSASRILQYLFDNSWLDALTRAVFVEFTVYNANVNLFCTVTLTLETSGLGTFFSHVTLQSLRLYPFTDGWHPFVVAAELTYFLFLFYYMVVQGKLMRKQKWGYFCSKWNLLEVAIILASWSALVVFVKRTILADRDLQRYREHRDEGISFSETAAADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMITSALRRAWGDISGFVAVILIMLLAYSFASNLVFGWKLRSYKTLFDAAETMVSLQLGIFNYEEVLDYSPILGSLLIGSCIVFMTFVVLNLFISVILVAFSE 2403
[Close]
BLAST of PKD2-2 vs. UniProt/SwissProt
Match: sp|Q4GZT3|PKD2_BOVIN (Polycystin-2 OS=Bos taurus OX=9913 GN=PKD2 PE=2 SV=1)

HSP 1 Score: 563.148 bits (1450), Expect = 0.000e+0
Identity = 319/737 (43.28%), Postives = 479/737 (64.99%), Query Frame = 3 
Query:  408 KFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTKQFNGENS-----------------------DYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE--GIDEDERRNQIHNIINSELEKYNYSDTIS 2540
            +  R LR LW T+L E++  +RE Y+K+ +REL  Y++FL +L I+ +GM+    +YYT+ +  LFLD      EK+ F T+S++ + W++  G  L+GLYW    + +   D+   +YYEN +LG+PRIRQL+VRN SC IP   + ++K CY  +S  +ED+  FG  N TAWIYTS + LN S ++ + + Y   G+Y DLSR +  T   + +L +N W+  GTR IFIDFT+YN NINLF V+RL+ EFP  GGV  S +F+ VKL+RY++TFD+F+AACE+IFCLFI+YY+VEE +EIR HKL YF  FWN LD+V+I++S+V    +IYRT++V+ L+Q  L ++N FP F+ L+Y Q QFNN  A+ +F  WIK+FK+I+FN+TM+QLS+T++R +KDLFGFA+MFFIIF A+A+L Y +FG+Q++DF    +   TQFRIILGD ++ ++E A+R++GP+YF  F FF+FF+L+NMFLAII DTY+EVK+++A QK E E++D  R      L  L+ K+  + DI +++         KL++DE R +LK +G+ DAEIE++F KYD+DGD+ L  +E + +  +L  E+E ++ D     +     S                           + +  +E+ +L RRVDRME +I  IV K+D ++     +++ K+ + +V+  LL+ +   E  G D +  R Q+  ++  ELE++   D  S
Sbjct:  194 RLVRGLRGLWGTRLMEESSTDREKYLKSVLRELATYLLFLIVLCILTYGMMSSSVYYYTRIMSQLFLDTPVSKMEKTNFKTLSSMEDFWKFTEGALLDGLYWKTQPSNRTEADNRSFIYYENLLLGVPRIRQLRVRNGSCSIPLDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGMIATYSGAGYYLDLSRTREETAAQVANLKKNVWLDRGTRAIFIDFTVYNANINLFCVIRLLIEFPATGGVIPSWQFQPVKLIRYVTTFDFFLAACEIIFCLFILYYVVEEILEIRIHKLHYFRSFWNCLDVVIIVLSVVAIGINIYRTSNVEALLQ-FLEDQNTFPNFENLAYWQTQFNNIAAVIVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALIKLKLKKNTVDDISESLRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEEDDDDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDNEIHREQMERLVREELERWESDDAAS 925
[Close]
BLAST of PKD2-2 vs. UniProt/SwissProt
Match: sp|Q6IVV8|PKD2_DANRE (Polycystin-2 OS=Danio rerio OX=7955 GN=pkd2 PE=1 SV=1)

HSP 1 Score: 562.377 bits (1448), Expect = 0.000e+0
Identity = 305/758 (40.24%), Postives = 474/758 (62.53%), Query Frame = 3 
Query:  345 NVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNE-QXXXXXXXXXXXXXXXXXXXXTKQFNGENSDYNKTNIDI----------------------DEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE--GIDEDERRNQIHNIINSELEKYNYSDTIS 2540
             +Y T    E +      C  +    +R LW T+L  ++  NRE+Y+KT +RE+I Y++FL  L II +GM+    +YYTK +  LFLD      E + F ++ST+ + W++  GPFLNG+YW+ WYN + + ++  L+YYEN +LG+PR+RQL+VRN SC + +  + ++  CY+ +S  NEDK  FG  N TAW +    SL  S Y+   S Y  GG+YQDLSR +  +   L+ L  N W+  GTR +F+DF++YN N+NLF ++RL+ EFP  GG   S +F+ V+LLRY+S++DYF+  CEV FCLF++YY+VEE +EIR H+L YF   WN LD++++ +S+   I +I RT++V   +  LL N + +P F+ L+  Q  FNN  AI +F++W+K+FK+I+FNKTM QLS+T++R +KDL GFA+MFFI+F A+A+L Y +FG+Q+ DF        TQFRIILGDFD+ ++E A  ++GP+YF  F FF+F +L+NMFLAII DTY+EVKA++A Q++E E+ D  + +    +  L+ K+  I DI D++  A      KL +DE R +L+ +G++DAEIE++F KYD DGD+ L  +E Q+  +      ++L  +     +  +G +   ++ + +                       +E+ +L RRVDRME +I  IV K+D ++     +++ K+ +  V+  +L+ +   E  G D + +R Q+  ++  ELE++   DT+S
Sbjct:  112 GLYPTPPAQEHRS-----CGKRILEKMRVLWDTRLLGESNSNREMYLKTVLREMITYILFLLTLCIITYGMVSTNMYYYTKVMSQLFLDTPLSSGEPTNFKSLSTMEDFWKFTEGPFLNGMYWELWYNNKSLPENQSLIYYENLLLGVPRLRQLRVRNESCSVHEDLRDEVYDCYNVYSPANEDKAPFGPKNGTAWRFKDESSLGESSYWGQVSTYGGGGYYQDLSRTREKSANQLQELKNNLWLDRGTRAVFLDFSIYNGNVNLFCIVRLLVEFPATGGAVPSWQFQTVRLLRYVSSWDYFVGMCEVSFCLFVLYYLVEEALEIRLHRLRYFKSLWNCLDVLIVALSVPAIIMNICRTSAVSHRLHFLLENHSTYPNFEPLARLQVHFNNLAAIIVFLSWVKLFKFINFNKTMNQLSTTMSRCAKDLMGFAIMFFIVFLAYAQLAYLVFGTQVNDFSTFQACIFTQFRIILGDFDFSEIEEADSVLGPIYFTTFVFFIFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKSYNRAMVKLKLKKSSINDIPDSLQQA----AGKLSFDELRQDLRGKGHSDAEIEAIFAKYDLDGDQELTEHEHQQMRDDLEKEREDLDLEHSSLPRPASGRSFSRSQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKMKRRDVLGRILDGVMEDERMGRDPELQREQMDRLVRDELERWESDDTMS 860
[Close]
BLAST of PKD2-2 vs. UniProt/SwissProt
Match: sp|O35245|PKD2_MOUSE (Polycystin-2 OS=Mus musculus OX=10090 GN=Pkd2 PE=1 SV=2)

HSP 1 Score: 548.51 bits (1412), Expect = 3.325e-179
Identity = 307/737 (41.66%), Postives = 472/737 (64.04%), Query Frame = 3 
Query:  408 KFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTKQFNGENS-----------------------DYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE--GIDEDERRNQIHNIINSELEKYNYSDTIS 2540
            +  R LR LW T+L E++  NRE Y+K+ +REL+ Y+ FL +L I+ +GM+    +YYT+ L  LF+D      EK+ F T+S++ + W++  G FL+GLYW    +     D+   ++YEN +LG+PR+RQL+VRN SC IP+  + ++K CY  +S  +ED+  FG  N TAW+YTS + LN S ++ + + Y   G+Y DLSR +  T   L  L  N W+  GTR  FIDF++YN NINLF V+RL+ EFP  GGV  S +F+ VKL+RY++ FD+F+AACE+IFC FI+YY+VEE +EIR H+L+YF  FWN LD+V++++S+V  + +IYR ++ + L+Q  L ++N FP F+ ++Y Q QFNN  A+ +F+ WIK+FK+I+FN+TM+QLS+T++R +KDLFGF +MF IIF A+A+L Y +FG+Q++DF    +   TQFRIILGD ++ ++E A+R++GP+YF  F FF+FF+L+NMFLAII D+Y+EVK+++A QK E E++D  R   +  L  L+ K    R+  DAI  +      KL++DE R +LK +G+ DAEIE++F KYD+DGD+ L   E + +  +L  E+E ++ +     +     S                           + +  +E+ +L RRVDRME +I  IV K+D ++     +++ K+ + +V+  LL+ +      G D +  R Q+  ++  ELE++   D  S
Sbjct:  190 RLVRGLRGLWGTRLMEESNANREKYLKSVLRELVTYLFFLVVLCILTYGMMSSNVYYYTRTLSQLFIDTPVSKTEKTNFKTLSSMEDFWKFTEGSFLDGLYWKAQTSNHTQADNRSFIFYENLLLGVPRLRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWMYTSEKELNGSSHWGIIASYSGAGYYLDLSRTREETAAQLAGLRRNFWLDRGTRAAFIDFSVYNANINLFCVVRLLAEFPATGGVVPSWQFQPVKLIRYVTAFDFFLAACEIIFCFFIIYYVVEEILEIRIHRLSYFRSFWNCLDVVIVVLSVVAMVINIYRMSNAEGLLQ-FLEDQNSFPNFEHVAYWQIQFNNISAVMVFLVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFTIMFSIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPLYFTTFVFFMFFILLNMFLAIINDSYSEVKSDLAQQKAEMELSDLIRKGCQKALVKLKLK----RNTVDAISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEREHQQMRDDLEKEREDLDLEHSSLPRPMSSRSFPRSLDDSEEEDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDARLGRDSEIHREQMERLVREELERWESDDAAS 921
[Close]
BLAST of PKD2-2 vs. UniProt/SwissProt
Match: sp|H2LRU7|PKD2_ORYLA (Polycystin-2 OS=Oryzias latipes OX=8090 GN=pkd2 PE=1 SV=2)

HSP 1 Score: 545.814 bits (1405), Expect = 6.206e-179
Identity = 305/778 (39.20%), Postives = 480/778 (61.70%), Query Frame = 3 
Query:  345 NVYKTQAVTEEQ--KYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFD-DKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNE-QXXXXXXXXXXXXXXXXXXXXTKQFNGENSDYNKTNIDI----------------------DEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE--GIDEDERRNQIHNIINSELEKYNYSDTISIGNVSSASRPGTARSTRK 2594
             +Y TQ +  +Q  ++   GC  +  + +R LW T+L ED   NRE Y+   +REL+ Y+ FL  + I+ +GMI    +YYTKA+  LFLD     +  K+F ++ST+ + W+Y  GPFL G+YW+ WYN Q +  +   +YYEN +LG+PR+RQ++V N +C I +  + +++ CY  ++  NED + FG  N TAW++T+   +N+S ++   S+Y  GG+YQDLSR +  +   L+ L ++ W+  GTR IF+DF++YN N+NL  + RL+ EFP  GGV TS +F+ ++L++Y+S++DYF+  CEV FCLF++YY+VEE +EI  H+L YF   WN LD++++ +S+V  I  I R A    L++G L N     +FD L+  Q QFNN  A+ +F  W+K+FK+I+FNKTM+QLS+T++R +KDL GFA+MFFIIF A+A+L Y +FG+Q+ DF     S  TQFRIILGDFD+ +++ A+ ++GP+YFI F  F+FF+L+NMFLAII DTY+EVKA++A  ++E EM D+ +      L  L+ K+  + DI D++  A      KL+YDE   +LK +G+ +AEI+++F KYD+DGD  L  ++ Q+  +      ++L  +    T+  +G +    + + +                       +E+ +L RRVDRME +I  IV K+D ++     +++ K+ +  V+  LL+ +   E  G D D  R Q+  ++  ELE++   D   + +  S  +P T    R 
Sbjct:  111 GLYPTQTLNGQQQDRHEHPGCMKRIFQNIRILWGTELMEDGDSNRERYLWNVLRELLTYIAFLITICILTYGMISTNMYYYTKAMSQLFLDAPLSSENPKTFRSLSTMEDFWKYTQGPFLGGMYWEVWYNNQSLPGNQSFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQGCYGVYTPSNEDNSPFGPQNGTAWVHTTESKMNASTHWGQVSKYGGGGYYQDLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGVLTSWQFQTLRLIKYVSSWDYFVGVCEVAFCLFVLYYVVEEVLEIHIHRLHYFKNLWNCLDVLIVTLSVVAIIMSITRAAMGGDLLKG-LENYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQGSVFTQFRIILGDFDFFEIKEANPVLGPIYFITFVLFIFFILMNMFLAIINDTYSEVKADMAQHRSEMEMTDFIKKGCTKALVKLRLKKTTVDDISDSLRQA----GGKLNYDELLQDLKEKGHTEAEIQAIFAKYDQDGDLELTEHDHQQMRDDLEKEREDLDLERNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEGMERAKLKRRDVLVRLLDGVMEDERLGRDADTHREQMERLVKEELERWETDD---VASQVSHPQPATPIGPRP 880
[Close]
BLAST of PKD2-2 vs. UniProt/SwissProt
Match: sp|Q13563|PKD2_HUMAN (Polycystin-2 OS=Homo sapiens OX=9606 GN=PKD2 PE=1 SV=3)

HSP 1 Score: 547.74 bits (1410), Expect = 7.749e-179
Identity = 316/737 (42.88%), Postives = 478/737 (64.86%), Query Frame = 3 
Query:  408 KFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTKQFNGENS-----------------------DYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE--GIDEDERRNQIHNIINSELEKYNYSDTIS 2540
            +  R LR LW T+L E++  NRE Y+K+ +REL+ Y++FL +L I+ +GM+    +YYT+ +  LFLD      EK+ F T+S++ + W++  G  L+GLYW    + Q   D+   ++YEN +LG+PRIRQL+VRN SC IP+  + ++K CY  +S  +ED+  FG  N TAWIYTS + LN S ++ + + Y   G+Y DLSR +  T   + SL +N W+  GTR  FIDF++YN NINLF V+RL+ EFP  GGV  S +F+ +KL+RY++TFD+F+AACE+IFC FI YY+VEE +EIR HKL YF  FWN LD+V++++S+V    +IYRT++V+ L+Q  L ++N FP F+ L+Y Q QFNN  A+ +F  WIK+FK+I+FN+TM+QLS+T++R +KDLFGFA+MFFIIF A+A+L Y +FG+Q++DF    +   TQFRIILGD ++ ++E A+R++GP+YF  F FF+FF+L+NMFLAII DTY+EVK+++A QK E E++D  R      L  L+ K+  + DI +++         KL++DE R +LK +G+ DAEIE++F KYD+DGD+ L  +E + +  +L  E+E ++ D     +     S                           + +  +E+ +L RRVDRME +I  IV K+D ++     +++ K+ + +V+  LL+ +   E  G D +  R Q+  ++  ELE++   D  S
Sbjct:  192 RLVRGLRGLWGTRLMEESSTNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQ-FLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEIHREQMERLVREELERWESDDAAS 923
[Close]
BLAST of PKD2-2 vs. TrEMBL
Match: A0A0H3YKM7 (PKD2-2 OS=Schmidtea mediterranea OX=79327 GN=PKD2-2 PE=2 SV=1)

HSP 1 Score: 1493.02 bits (3864), Expect = 0.000e+0
Identity = 797/797 (100.00%), Postives = 797/797 (100.00%), Query Frame = 3 
Query:  207 MHNYGMNKSRPPTADSRRVLWNDEDYVESEHMDNEPTAMEDQHQIENVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTKQFNGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEGIDEDERRNQIHNIINSELEKYNYSDTISIGNVSSASRPGTARSTRKD 2597
            MHNYGMNKSRPPTADSRRVLWNDEDYVESEHMDNEPTAMEDQHQIENVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFIVYYIVEETIEIRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLFGFAVMFFIIFFAFAELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYFILFTFFVFFVLINMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQKNLEGELNIEKELIEKDIEETKQFNGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEGIDEDERRNQIHNIINSELEKYNYSDTISIGNVSSASRPGTARSTRKD
Sbjct:    1 MHNYGMNKSRPPTADSRRVLWNDEDYVESEHMDNEPTAMEDQHQIENVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFIVYYIVEETIEIRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLFGFAVMFFIIFFAFAELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYFILFTFFVFFVLINMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQKNLEGELNIEKELIEKDIEETKQFNGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEGIDEDERRNQIHNIINSELEKYNYSDTISIGNVSSASRPGTARSTRKD 797
[Close]
BLAST of PKD2-2 vs. TrEMBL
Match: A0A267F8W2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig009158g1 PE=4 SV=1)

HSP 1 Score: 699.893 bits (1805), Expect = 0.000e+0
Identity = 402/820 (49.02%), Postives = 546/820 (66.59%), Query Frame = 3 
Query:  222 MNKSRPPT-------ADSRRVLWNDEDYVESEHMDNEPTAMEDQHQIENVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEK-SFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITD--DTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTKQFNGENSDYNKTN-----------IDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEGIDEDERRNQIHNIINSELEKYNYSDTISIGNVSSASRPGTARSTRKD*STLRKQ 2618
            M  SRP T       A S+  + + + +     MDN P  ++     ++  +T  V +++K    GCW +F+R +  +W T +TE+T E+RE YIKTT+RELIIY +FL +LMI+ FGM     +YYT+ L  LFLD   D   K +F  + +I + W Y+    L GLYW+ WYN  + TD  +T+ +YYEN++LG+PR+RQL+VRNNSC I   F+  +  CYS +SS  + K+ FG  NSTAW YTS + L+   Y +  + Y  GG+Y DL R++  TL ++  L+   WV   TRV F+DFT+YN NINLF V++L+ EFP  GG   S EFR VKLLRY+   DYF+  CE IF LFI YYIVEE IEI+++KL YF  FWNWLDI+VI+ISLVCA F++YRT +V K +  LL +EN++P FDFLSY QQQFN+ +AI +F AW+KIFKYISFNKTMTQLSSTL   +KDL GFAVMFFIIFFAFA+LGY IFG+Q++DF    ++  T FRIILGDFD+  L++AHR++GP+YF+L+ FFVFFVLINMFLAII DTY+EVK+E+A Q N+FEM DYF+  A  VL  L FK+ KI DIQ AI +AD+N+D++LD++EWR ELK RGYAD EIE++F KYD DGDR L+  EQ+ ++ EL  +K  +   IEET+Q     S     +           + ++E+ +L RRVDRME +I  IV K+D +L     ++K K+ + + +S LL+++   +G  E E+R  +  ++  ELE++   +    G  S A  P +AR TR   S  R+Q
Sbjct:    1 MATSRPATGGVGASRAKSQASVASSQAWSNDPAMDN-PEMLDQDPAFDS--QTNIVAKDEK---AGCWQRFRRGIHVIWRTNMTENTKEDREKYIKTTLRELIIYCIFLIVLMILTFGMTSTTMYYYTQVLSALFLDATDDPVNKPTFRNLGSIPDWWTYMQNALLTGLYWNTWYNSNNFTDPRETNFIYYENKLLGVPRLRQLRVRNNSCNIASNFKDTIPFCYSTYSSSAQSKDPFGYMNSTAWNYTSDDILDGQSYSAQLASYPSGGYYIDLGRDRDTTLAIVNELYSGLWVDRATRVAFVDFTVYNANINLFCVIKLVMEFPATGGALPSWEFRTVKLLRYVEPMDYFVLVCEGIFMLFICYYIVEEAIEIKRNKLDYFKSFWNWLDILVIVISLVCACFNVYRTIAVGKKLTSLLQDENKYPDFDFLSYWQQQFNHGIAITVFFAWVKIFKYISFNKTMTQLSSTLGACAKDLLGFAVMFFIIFFAFAQLGYLIFGTQVQDFREFQQAIFTLFRIILGDFDFNSLQTAHRVLGPLYFLLYVFFVFFVLINMFLAIINDTYSEVKSELANQPNDFEMTDYFKQRAGKVLDKLSFKRDKIVDIQKAIQSADLNNDRQLDFEEWRAELKQRGYADGEIEALFAKYDLDGDRVLDEEEQRRMQAELEGQKSALNDQIEETEQQQERPSTARSLDGEGAIGGGGGGVSVEEFTVLARRVDRMEHSIGSIVTKIDSVLVKLESMEKAKLRRRETMSKLLDSIAECDGASEAEKREHMERLVREELERWESDNAAGSGADSVA--PSSARGTRSSASGSRRQ 812
[Close]
BLAST of PKD2-2 vs. TrEMBL
Match: A0A1I8GRD3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 696.812 bits (1797), Expect = 0.000e+0
Identity = 398/837 (47.55%), Postives = 544/837 (64.99%), Query Frame = 3 
Query:  222 MNKSRPPT-------ADSRRVLWNDEDYVESEHMDNEPTAMEDQHQIENVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEK-SFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITD--DTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXX----------XXXXXXXTKQFNGENS------------------DYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEGIDEDERRNQIHNIINSELEKYNYSDTISIGNVSSASRPGTARSTRKD*STLRKQ 2618
            M  SRP T       A S+  + + + +     MDN P  ++     ++  +T  V +++K    GCW +F+R +  +W T +TE+T E+RE YIKTT+RELIIY +FL +LMI+ FGM     +YYT+ L  LFLD   D   K +F  + +I + W Y+    L GLYW+ WYN  + TD  +T+ +YYEN++LG+PR+RQL+VRNNSC I   F+  +  CYS +SS  + K+ FG  NSTAW YTS + L+   Y +  + Y  GG+Y DL R++  TL ++  L+   WV   TRV F+DFT+YN NINLF V++L+ EFP  GG   S EFR VKLLRY+   DYF+  CE IF LFI YYIVEE IEI+++KL YF  FWNWLDI+VI+ISLVCA F++YRT +V K +  LL +EN++P FDFLSY QQQFN+ +AI +F AW+KIFKYISFNKTMTQLSSTL   +KDL GFAVMFFIIFFAFA+LGY IFG+Q++DF    ++  T FRIILGDFD+  L++AHR++GP+YF+L+ FFVFFVLINMFLAII DTY+EVK+E+A Q N+FEM DYF+  A  VL  L FK+ KI DIQ AI +AD+N+D++LD++EWR ELK RGYAD EIE++F KYD DGDR L+  EQ+ ++ EL  +K             ++     +  +GE +                        + ++E+ +L RRVDRME +I  IV K+D +L     ++K K+ + + +S LL+++   +G  E E+R  +  ++  ELE++   +    G  S A  P +AR TR   S  R+Q
Sbjct:    1 MATSRPATGGVGASRAKSQASVASSQAWSNDPAMDN-PEMLDQDPAFDS--QTNIVAKDEK---AGCWQRFRRGIHVIWRTNMTENTKEDREKYIKTTLRELIIYCIFLIVLMILTFGMTSTTMYYYTQVLSALFLDATDDPVNKPTFRNLGSIPDWWTYMQNALLTGLYWNTWYNSNNFTDPRETNFIYYENKLLGVPRLRQLRVRNNSCNIASNFKDTIPFCYSTYSSSAQSKDPFGYMNSTAWNYTSDDILDGQSYSAQLASYPSGGYYIDLGRDRDTTLAIVNELYSGLWVDRATRVAFVDFTVYNANINLFCVIKLVMEFPATGGALPSWEFRTVKLLRYVEPMDYFVLVCEGIFMLFICYYIVEEAIEIKRNKLDYFKSFWNWLDILVIVISLVCACFNVYRTIAVGKKLTSLLQDENKYPDFDFLSYWQQQFNHGIAITVFFAWVKIFKYISFNKTMTQLSSTLGACAKDLLGFAVMFFIIFFAFAQLGYLIFGTQVQDFREFQQAIFTLFRIILGDFDFNSLQTAHRVLGPLYFLLYVFFVFFVLINMFLAIINDTYSEVKSELANQPNDFEMTDYFKQRAGKVLDKLSFKRDKIVDIQKAIQSADLNNDRQLDFEEWRAELKQRGYADGEIEALFAKYDLDGDRVLDEEEQRRMQAELEGQKSALNDQIEETEQQQERPSTARSLDGEGAIGGRPRSSRRGGGGGGGGGGGGGGVSVEEFTVLARRVDRMEHSIGSIVTKIDSVLVKLESMEKAKLRRRETMSKLLDSIAECDGASEAEKREHMERLVREELERWESDNAAGSGADSVA--PSSARGTRSSASGSRRQ 829
[Close]
BLAST of PKD2-2 vs. TrEMBL
Match: A0A1I8FWB2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031000g1 PE=4 SV=1)

HSP 1 Score: 691.804 bits (1784), Expect = 0.000e+0
Identity = 395/835 (47.31%), Postives = 541/835 (64.79%), Query Frame = 3 
Query:  222 MNKSRPPT-------ADSRRVLWNDEDYVESEHMDNEPTAMEDQHQIENVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEK-SFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITD--DTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXX----------XXXXXXXTKQFNGENS----------------DYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEGIDEDERRNQIHNIINSELEKYNYSDTISIGNVSSASRPGTARSTRKD*STLRKQ 2618
            M  SRP T       A S+  + + + +     MDN P  ++     ++  +T  V +++K    GCW +F+R +  +W T +TE+T E+RE YIKTT+RELIIY +FL +LMI+ FGM     +YYT+ L  LFLD   D   K +F  + +I + W Y+    L GLYW+ WYN  + TD  +T+ +YYEN++LG+PR+RQL+VRNNSC I   F+  +  CYS +SS  + K+ FG  NSTAW YTS + L+   Y +  + Y  GG+Y DL R++  TL ++  L+   WV   TRV F+DFT+YN NINLF V++L+ EFP  GG   S EFR VKLLRY+   DYF+  CE IF LFI YYIVEE IEI+++KL YF  FWNWLDI+VI+ISLVCA F++YRT +V K +  LL +EN++P FDFLSY QQQFN+ +AI +F AW+KIFKYISFNKTMTQLSSTL   +KDL GFAVMFFIIFFAFA+LGY IFG+Q++DF    ++  T FRIILGDFD+  L++AHR++GP+YF+L+ FFVFFVLINMFLAII DTY+EVK ++A Q N+FEM DYF+  A  V   L FK+ KI DIQ AI +AD+N+D++LD++EWR ELK RGYAD EIE++F KYD DGDR L+  EQ+ ++ EL  +K             ++     +  +GE +                      + ++E+ +L RRVDRME +I  IV K+D +L     ++K K+ + + +S LL+++   +G  E E+R  +  ++  ELE++   +    G  S A  P +AR  R   S  R+Q
Sbjct:    1 MATSRPATGGVGASRAKSQASVASSQAWSNDPAMDN-PEMLDQDPAFDS--QTNIVAKDEK---TGCWQRFRRGIHVIWRTNMTENTKEDREKYIKTTLRELIIYCIFLIVLMILTFGMTSTTMYYYTQVLSALFLDSTDDPVNKPTFRNLGSIPDWWTYMQNALLTGLYWNTWYNSNNFTDPRETNFIYYENKLLGVPRLRQLRVRNNSCNIASNFKDTIPFCYSTYSSSAQSKDPFGYMNSTAWNYTSDDILDGQSYSAQLASYPSGGYYIDLGRDRDTTLAIVNELYSGLWVDRATRVAFVDFTVYNANINLFCVIKLVMEFPATGGALPSWEFRTVKLLRYVEPMDYFVLVCEGIFMLFICYYIVEEAIEIKRNKLDYFKSFWNWLDILVIVISLVCACFNVYRTIAVGKKLTSLLQDENKYPDFDFLSYWQQQFNHGIAITVFFAWVKIFKYISFNKTMTQLSSTLGACAKDLLGFAVMFFIIFFAFAQLGYLIFGTQVQDFREFQQAIFTLFRIILGDFDFNSLQTAHRVLGPLYFLLYVFFVFFVLINMFLAIINDTYSEVKNDLANQPNDFEMTDYFKQRAGKVFDKLSFKRDKIVDIQKAIQSADLNNDRQLDFEEWRAELKQRGYADGEIEALFAKYDLDGDRVLDEEEQRRMQAELEGQKSALNDQIEETEQQQERPSTARSLDGEGAIGGRPRSSRRGGGGGGGGGGGGVSVEEFTVLARRVDRMEHSIGSIVTKIDSVLVKLESMEKAKLRRRETMSKLLDSIAECDGASEAEKREHMERLVREELERWESDNAAGSGADSVA--PSSARGARSSASGSRRQ 827
[Close]
BLAST of PKD2-2 vs. TrEMBL
Match: A0A267G2D4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig010261g1 PE=4 SV=1)

HSP 1 Score: 681.789 bits (1758), Expect = 0.000e+0
Identity = 373/763 (48.89%), Postives = 520/763 (68.15%), Query Frame = 3 
Query:  285 VESEHMDNEPTAMEDQHQIEN--VYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITD--DTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTK------QFNGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEGIDEDERRNQIHNIINSELEKYNYSDTISI 2543
            V    + + P A E Q Q E   V             S GCW  F + +R++W T +TEDT  NRELYIKTT+REL+IY +FL +LMI++ GM     FYYT+AL  LF      D +  FT +++I   W +  GP ++GLYW+ WYN  + +D  + + +YY+N++LG+PRIRQL+VRNNSC +   F+ ++  C+S FS   E+K  FG  NS+AW Y++ + L+   +    S Y   G+Y DLSRNK  +   L  LF   W+  GTRV+F+DFT+YN NINLF V++L+ E P  GG   S++FR VKLLRY+   DYF+  CE IF LFI YYIVEE IEI+++KL YF  FWNWLDI+VI++SL+C  F++YRT +V K +Q LL +E++FP FDFLSY QQQFNNA+A  LF+AW+K FKYISFNKTMTQLSSTL+  +KDL GFAVMFFI+FFAFA+LGY IFG+QI+DF     S  T FRIILGDFD+ QLESA+R++GP++F+L+ FFVFFVLINMFLAII DTY+EVK ++A Q NEFEMADYF+  A  +LQ L  KQ+KI DIQ A+  AD+N DK+LD++EWR+ELK+RGYAD EIE++F KYD+DGDR L+  EQ+ +  EL  ++  I + I+  K      +     + + +  +  +E++ L  RVDRME +I  +V K+D +L     ++  K  + + +  LL+A+N TEG+ ++ +R ++  ++  ++++++   ++ +
Sbjct:   41 VSEPPLADAPPAGELQTQPEKSEVSGGDIGGPVLIEGSEGCWPNFVKTVRAIWRTNMTEDTKTNRELYIKTTLRELVIYCIFLAVLMILSLGMTSTNMFYYTQALSGLFTATPAADTQTPFTRINSIPGWWSFAKGPLMDGLYWESWYNSDNFSDPKEKNFIYYDNKLLGVPRIRQLRVRNNSCTVADDFKDEITFCHSSFSPGVEEKRPFGYMNSSAWNYSTEKQLDGRSFSGEISSYPGSGYYVDLSRNKEDSTAQLNELFTGLWIDRGTRVVFVDFTVYNANINLFCVVKLVLELPATGGAIPSSDFRTVKLLRYVEPKDYFVLVCEGIFMLFICYYIVEEVIEIKRNKLDYFKTFWNWLDIIVILVSLICGGFNVYRTVTVGKKLQELLQDESRFPDFDFLSYWQQQFNNAIAFTLFLAWVKFFKYISFNKTMTQLSSTLSACAKDLMGFAVMFFIVFFAFAQLGYLIFGTQIKDFREFHHSVFTLFRIILGDFDFHQLESANRVLGPLFFLLYVFFVFFVLINMFLAIINDTYSEVKTDLANQPNEFEMADYFKERASKMLQKLNLKQEKILDIQSALKTADMNDDKQLDFEEWRSELKARGYADGEIEALFSKYDQDGDRVLDEREQRAMTSELEGQRAAINRQIDSEKVRPASGKGAAAAASHAEPQVTAEEFSALAHRVDRMERSIGSVVSKIDAVLVKLDAVEAGKAKRREQMGKLLDAINETEGVTDEYKRQEMERMVREQVQRFDGEPSLVV 803
[Close]
BLAST of PKD2-2 vs. Ensembl Cavefish
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:103043751])

HSP 1 Score: 568.155 bits (1463), Expect = 0.000e+0
Identity = 307/765 (40.13%), Postives = 489/765 (63.92%), Query Frame = 3 
Query:  414 KRIL---RSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNE-QXXXXXXXXXXXXXXXXXXXXTKQFNGENSDYNKTNIDI----------------------DEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE--GIDEDERRNQIHNIINSELEKYNYSDTIS---------IGNVS--SASRPGTARST 2588
            KRIL   R LW T+L ED+  +RE+Y+K  +RE + Y+ FL  L II +GM+    ++YTK +  LFLD      + + F T+ST+ + W+Y  GPFLNG+YWD WYN + + ++  L+YYEN +LG+PR+RQ+KV N SC + +  + ++  CYS +S  +EDK  FGL N+TAW+Y+    L  S Y+   + Y  GG+YQDL+R++  + + L+ L +N W+  GTR +F+DF++YN N+NLF ++R++ EFP  GG  TS +F+ V+L+RY+S++DYF+  CEV+FCLF++YY+VEE +EIR H+L YF   WN LD++++ +S    I +IYRT++V   ++ LL N + +P F  L+  Q QFN+  A+ +F+AW+K+FK+I+FNKTM+QLS+T++R +KDL GFA+MFFI+F A+A+L Y +FG+Q+ DF        TQFRIILGDFD+ ++E  +R++GP+YF  F FF+F +L+NMFLAII DTY+EVKA++A Q++E E+ D  +   +  +  L+ ++  + DI D++  A      KL++DE R +L+ +G++DAEIE++F KYD DGD+ L+ +E Q+  +      ++L  +     +  +G +   ++ + +                       +E+ +L RRVDRME +I  IV K+D ++     +++ K+ + +V+  LL+ +   E  G D +  R  +  ++  ELE++   D IS         IG  +   ++RP ++ ST
Sbjct:  130 KRILAKLRILWGTRLMEDSESSREVYLKNVLRETVTYIFFLITLCIITYGMVSTNMYFYTKVMSQLFLDTPLSKGDPTTFKTLSTMEDFWKYTEGPFLNGMYWDVWYNNKSLPENQSLIYYENLLLGVPRLRQVKVLNKSCPVHEDLKDEVYDCYSIYSPASEDKAPFGLKNNTAWVYSEENILGESSYWGEVATYRGGGYYQDLARSREESARQLKELKDNLWLDRGTRAVFLDFSVYNGNVNLFCIVRMLVEFPATGGAVTSWQFQTVRLVRYVSSWDYFVGTCEVVFCLFVLYYMVEEVLEIRLHRLRYFKSLWNCLDVIIVTLSAPAIIMNIYRTSAVSNRLRYLLENHSTYPNFQPLAQVQVQFNHLAAVIVFLAWVKLFKFINFNKTMSQLSTTMSRCAKDLLGFAIMFFIVFLAYAQLAYLVFGNQLNDFSTFQACIFTQFRIILGDFDFSEIEETNRVLGPIYFTTFVFFMFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKGYQKAMVKLRLRKTTVDDISDSLRQA----GGKLNFDELRQDLRGKGHSDAEIEAIFAKYDLDGDQELSEHEHQQMKDDLEKEREDLDLERSSLPRPMSGRSFSRSQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLDGVMEDERMGRDTEVHREHMEKLVREELERWESDDAISQVSHQQATPIGAQARIRSARPASSLST 890
[Close]
BLAST of PKD2-2 vs. Ensembl Cavefish
Match: pkd2l1 (polycystic kidney disease 2-like 1 protein [Source:NCBI gene;Acc:103031316])

HSP 1 Score: 542.347 bits (1396), Expect = 1.311e-179
Identity = 314/749 (41.92%), Postives = 482/749 (64.35%), Query Frame = 3 
Query:  231 SRPPTADSRRVLWNDEDYVESEHMDNEPTAMEDQHQIENVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDT-DLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTK---QFNGENSDYN-KTN---IDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE 2453
            + PP   S   ++N +    S+       +  + +  EN    Q    E+K  S+GC     R ++ LW T LT+DT ENREL+++TT+REL++Y+VFL  + ++ +GM    T+YYTK +  LF++    D   +F ++ T+ + W Y  GP L+GLYW  WYN Q +   T   +YYEN +LG+PR+RQLKV+N SC++ K F+ ++  C+  ++ + ED ++FGL N TAW Y + + L  S ++ + + Y  GG+YQDL+  K  +  +L +L  N W+  GTR +FIDF+ YN NINLF V+RL+ EFP  GG   S + R VKL+RYI+T+DYFI  CE++FC+FI+YYIVEE +E+R HKL+YF   WN LD+V+I++++V  +F+++RT  V KL+  LL   + +  F+FL++ Q Q+NN  A+NLF AWIKIFKYISFNKTMTQLSSTL R + D+ GFA+MFFI+FFA+A+LGY +FG+++E F    K   TQFRIILGDFDY  +E A+R++GP+YF  + FFVFFVL+NMFLAII DTY+EVK E+A+QK++ ++ D  + +       L+ K++KI D+Q  + +      K+L++ ++R  LK  G+AD EI + F K+D DG++ L+  EQ+ ++ EL  +++ +  ++       + NG+ +D N KTN   +   ++ +L ++V  +E +++  + K+D +++     D  K ++       L   N  E
Sbjct:   36 TPPPVHRSISTVYNPQPLFHSQLDSMGKVSAPNPYPAENSVMNQY--HEKK--SSGCCSFLLRGIKGLWGTTLTKDTTENRELFVRTTLRELVVYIVFLVDMCLLTYGMTSSTTYYYTKVMTDLFVNAP-SDSGVTFQSIGTMDDFWSYAQGPLLDGLYWTSWYNNQSLQTGTHSFIYYENMLLGVPRVRQLKVKNKSCKVHKDFEEEISDCFDVYNEKKEDDSSFGLINGTAWQYHTEKELKGSNHWGMLATYSGGGYYQDLALTKEESAGVLANLNNNLWLDHGTRAVFIDFSTYNANINLFCVIRLVVEFPATGGAIPSYQIRTVKLIRYITTWDYFIIGCEIVFCVFILYYIVEEILELRIHKLSYFKSIWNILDVVIIMLAIVAIVFNVFRTIKVDKLLGNLLKEPSIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCATDILGFAIMFFIVFFAYAQLGYLLFGTEVESFSTFHKCIFTQFRIILGDFDYDGIERANRVLGPIYFFTYVFFVFFVLLNMFLAIINDTYSEVKEELASQKDDLQITDLIKQSYSKTFMKLKLKKEKISDVQKVLRSG----SKELEFKDFRETLKEMGHADHEISAAFSKFDYDGNQILDKEEQETMKQELEEKRDALSVELHNLGINYEKNGKETDDNEKTNSVLVTAQQFQMLVKQVVELECSLATTMAKIDVVMEKLGLQDAGKTNKKDATGKHLTIRNEQE 775
[Close]
BLAST of PKD2-2 vs. Ensembl Cavefish
Match: pkd1l2a (polycystin 1 like 2 [Source:NCBI gene;Acc:103044173])

HSP 1 Score: 171.014 bits (432), Expect = 9.431e-43
Identity = 130/478 (27.20%), Postives = 249/478 (52.09%), Query Frame = 3 
Query:  495 VRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGL--NNS----------TAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAE 1892
            +RE++IY+ FL +L+++A+G  D   FY T+ ++  F +   D          T   V+Q+     LN L+      GQ     TD     ++++G  R+RQ++V++ SC + +  +  +  C++ +S + ED  ++G   N S          T W Y +   L +   +   + Y  GGF  DL  N+      L+ LFEN+W+ + TR IF++FT+YN N+NLF ++ L+FE   +G  +  +E + V+L +       F+ A EV++ LFI YY+ ++   +++ K  YF   WN LD+ +II+S       I RT    + I+   ++++++  F+  +         +A  + +A +K++  +  N  +  ++STL R+  D+ GF V+  I+F A++     ++G ++  +  L+ +A T   + LG F+Y+++   + ++G         F+ FV++N+F+++I   ++E
Sbjct: 2090 IREILIYMGFLWMLLLVAYGQRDPNAFYLTQHIQQSFSNGISDSM--------THGEVFQWANSTLLNNLF------GQQPGFITD---GNSKLVGNARLRQVRVQDGSCRVDRSMRNSVPDCHAPYSWDMEDLGSYGPGWNPSIDANLSKTLPTPWQYQTQSRLRAHPIWGGVAVYRGGGFVVDLGPNRENASSSLQYLFENTWLDMFTRAIFVEFTVYNANVNLFCIVTLMFETTAVGAFQYRSELQSVRLYQSTGGLHIFVMASEVVYFLFIFYYMFQQGKLMKQQKWEYFRSKWNLLDMAIIILSWSALPVFIKRTLLGNQSIEYYQNHKDEYAGFNETATADAVLGYIIAFLVLLATVKLWHLLRLNPKLHMITSTLQRAWNDISGFIVVMTIMFLAYSVACNLLYGWKLYSYRTLLNAAQTIVSLQLGIFNYEEVLDYNPVLGAFIVGSCIIFMTFVVLNLFISVILVAFSE 2550
[Close]
BLAST of PKD2-2 vs. Ensembl Cavefish
Match: ENSAMXT00000006495.2 (pep primary_assembly:Astyanax_mexicanus-2.0:5:35007331:35041448:1 gene:ENSAMXG00000006274.2 transcript:ENSAMXT00000006495.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 156.762 bits (395), Expect = 2.679e-38
Identity = 125/511 (24.46%), Postives = 257/511 (50.29%), Query Frame = 3 
Query:  429 SLWATKLTEDTGENRELYIK-----TTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNS------------TAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQG------LLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAE 1892
            S +      D G+ +E++IK       + E++IY+ F  +L++ A+   D   F+ T+ ++  F +   D   +    +   S++   LFG           Y+G  ITD        ++++G  R+RQ++V+ +SC      +  +  C++ +S E ED  ++G   +            T W Y +   L +   +   + Y  GGF  DL  ++  +  +L+ LFEN+W+ + TR +FI+FT+YN N+NLF ++ L+ E   +G  +   E + ++L +        ++  E I+ LFI+YY+  +   +++ K  YF   WN L++ +I++S   + F ++    ++K++QG         + NQFP+F   +          A+ + +A IK++  +  N  +  +++TL ++  D+  F V+  I+F A++ +   +FG ++  ++ LI +A     + LG F+Y+++   + ++G         F+ FV++N+F+++I + +++
Sbjct: 1182 SFYQPPPPSDVGKMKEIWIKDQKAFALIWEILIYLGFFCMLLMAAYSQRDPNAFFLTRHIQQSFSNGISDSMSQQDVFIWANSSLLTNLFGQ----------YSG-FITDG------NSKLVGTARLRQVRVQKSSCRKASSVRSSVPDCHAPYSWEVEDMGSYGPGWTSLIDSNMSKALFTPWQYQTQSRLRAHTVWGGMALYRGGGFVVDLEPDQQNSSSVLQYLFENAWLDIYTRALFIEFTVYNANVNLFCIVTLMLETTAVGAFQYRTELQNIRLFQTTDGIPTLVS--EAIYFLFILYYMFLQAKLMKQQKWEYFRNKWNILELAIILLSW--SAFSVF----IKKMVQGDQDLKYYQDHRNQFPSFYETAAADSVLGYLTAVLVLLATIKMWHLMRLNSKLNMITNTLQQAWSDISSFIVVIVIMFLAYSIVSNLLFGWKLYTYKTLIDAATAMVSLQLGIFNYEEILDLNPVLGAFIIGSCIIFMTFVVLNLFISVILEAFSQ 1667
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BLAST of PKD2-2 vs. Ensembl Cavefish
Match: pkd1a (polycystic kidney disease 1a [Source:ZFIN;Acc:ZDB-GENE-100707-1])

HSP 1 Score: 74.7146 bits (182), Expect = 5.504e-13
Identity = 59/249 (23.69%), Postives = 110/249 (44.18%), Query Frame = 3 
Query:  996 GGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKL--LRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSAL 1736
            GGF Q+LSR    +  +++ L  + W    TR +F++F+LYN N +L +V  L+ EFP     ++S + +   L  L +      F+    +IF ++             +   +YF   WN   +  ++++ V +   + R+A   +L    L     F  F  L+   Q      A  LF+  +K    + F +       TL RS  +L   A+   ++  A++ +G+ +F S +E +  +  + L
Sbjct: 3727 GGFVQELSRRMEDSRSLIQQLLSHQW----TRALFVEFSLYNTNTDLLAVFTLLLEFPVSERAQSSLDLKTCSLHTLHHGLDLSLFLTLLLMIFIIYFSVREGVAA---HRQGRSYFLRVWNLAGMCTLLLAAVVSALHLSRSALATRLWASFLQQRESFTDFFPLAQQNQVLTQLNATLLFLLVLKASHQLRFLREWAVFGRTLRRSVWELLAAALALLVLLLAYSHMGHLLFHSVLEGYATVSSACL 3968
[Close]
BLAST of PKD2-2 vs. Ensembl Sea Lamprey
Match: pkd2l1 (polycystic kidney disease 2-like 1 [Source:ZFIN;Acc:ZDB-GENE-030616-558])

HSP 1 Score: 560.066 bits (1442), Expect = 0.000e+0
Identity = 317/648 (48.92%), Postives = 443/648 (68.36%), Query Frame = 3 
Query:  429 SLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTKQFNGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLL 2369
              W T+LTE     RE Y KTT+RELIIYVVFL  L ++ FGM++  T+YYTK +  LF++      + + F ++S++ + W+ + GP L+GLYW++WYNG  +  +   + YEN +LG+PR+RQLKVRN SC I  +F+  +  CY  +S   EDK  FG    TAW Y S E L+ S ++ L ++Y   G+Y+DLSR K  +  ML+ L +  W+  GTR +FIDFT YN NINLF V+RL+ EFP  GG   S +FR VKL+RY+S FDYFI ACEVIFC FI+YY+VEE +E+R H + YF   WN LDI+VI++S+V  IF+I RT +V  L+  LL++ N +  F++L++ Q QFNN +AIN+F AWIKIFKY+SFNKT+TQLSSTL R +KD+ GFAVMFFIIFFA+A+ GY +FGSQ+EDF + +    TQFRIILGDFD+  +E+A+RI+GP+YF  + FFVFFVL+NMFLAII DTY +VKAE+A  K++FE+ D+F+   +N+L  L+ K+  I D+Q A+ +A     K L+YD WR  L   G++D EI + F K+DKD D  L+ +EQK L  EL  +K+ + +DIE  K  +      + + +  D++N    RV +ME ++  ++ K++ LL
Sbjct:   10 GFWGTRLTE-VNSTREQYFKTTLRELIIYVVFLIDLCLLTFGMMNTNTYYYTKVMMDLFVESPVSPIDGTNFNSISSMDDFWKVVQGPVLDGLYWEKWYNGDQLPVNLSFIQYENVMLGVPRVRQLKVRNGSCTIYPLFRNIIPGCYDGYSCGEEDKETFGRGTGTAWKYWSEEELSGSSHWGLLAQYSGAGYYRDLSRRKNESAPMLQELKDYLWLDHGTRAVFIDFTTYNGNINLFCVVRLVVEFPLTGGALPSYQFRTVKLIRYVSAFDYFIMACEVIFCCFILYYVVEECLELRLHGMKYFKSVWNCLDIIVIVLSMVAIIFNICRTIAVSNLLGALLNDPNIYADFEYLAFWQTQFNNMLAINVFFAWIKIFKYVSFNKTLTQLSSTLARCAKDVLGFAVMFFIIFFAYAQTGYLVFGSQVEDFSSFVNCIFTQFRIILGDFDFHAIENANRILGPIYFTTYIFFVFFVLLNMFLAIINDTYTDVKAELADTKDDFEIGDFFKQGYKNMLNKLKMKKDDIADMQRALDSA----GKHLEYDIWRKNLIRLGHSDEEIAAAFSKFDKDSDNVLDEDEQKQLRAELEGQKDKLNEDIEALKTMDNSGKPGDASRVTKDDFNRFASRVAKMESSMDSLMSKVESLL 652
[Close]
BLAST of PKD2-2 vs. Ensembl Sea Lamprey
Match: pkd2l1 (polycystic kidney disease 2-like 1 [Source:ZFIN;Acc:ZDB-GENE-030616-558])

HSP 1 Score: 536.184 bits (1380), Expect = 1.447e-178
Identity = 299/651 (45.93%), Postives = 427/651 (65.59%), Query Frame = 3 
Query:  225 NKSRPPTADSRRVLWNDEDYVESEHMDNEPTAMEDQHQIENVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEK-SFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXX--XXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNE 2168
            ++  P   D  +       YV+S     E    +  H+ E         E+Q   S G     K +LR LW T+LTED   +R+ Y+KTT+REL +Y+ FL  L+I+ FGM   + + YT A+  LFL       +  +F ++ T  + W+ + GP LNGLYW++WYN   + ++   +YYEN +LG+PRIRQLKVRN+SC +   FQ D++ CY+ +S + EDK +FG    T W Y++   +N S ++ L + Y  GG+Y DL+R+K+ +  +L+ LF+  W+  GTR I IDF+ YN NINLFSV+RL+ EFP  GG   S++   VKL+RY++  DYFI ACE IFC FI+YYIVEE +E+  HK AYF   WN LD++VI++S+V  IF++YRT +V KL++ LL   N++  F FL++ Q Q+NN VA+N+F  WIK FKY+SFNKTMTQLSSTL R +KD+ GFAVMFFIIFFA+A+LGY +FG+Q+EDF        TQFRIILGDFD+  +E+A+R++GP+YF  + F V    +  NMFLAII DTYAEVK E+A ++NEF++  YF+    ++ + L   +  I D+  ++L+A   S +K++YD+WR +LK  G++D EIE+ F K+DKD +  L+ NE
Sbjct:   40 SRGAPDAGDYPKGKPLPGSYVDSSSAVYEEIPEDGPHKAE---------EDQ---SGGPKKSRKSVLRGLWGTRLTEDI-TDRDKYVKTTLRELFVYIAFLINLIILTFGMTSDLMYKYTLAMDNLFLQNTVSPNDSVNFNSIFTFDDFWKVVQGPVLNGLYWEKWYNDIPLVENQSFIYYENFLLGVPRIRQLKVRNDSCTVHADFQKDVQGCYAAYSEDAEDKASFGPATGTPWKYSTSSDMNGSSHWGLLATYSGGGYYLDLTRSKSESAILLQDLFDKQWLDRGTRAILIDFSSYNGNINLFSVIRLLVEFPPTGGAVPSSQIYTVKLIRYVTGSDYFILACEGIFCCFILYYIVEEILELSIHKFAYFKSVWNCLDLLVIMLSVVAIIFNVYRTVTVNKLLKALLDEPNRYGNFQFLAFWQTQYNNMVAVNVFFCWIKFFKYVSFNKTMTQLSSTLARCAKDVLGFAVMFFIIFFAYAQLGYLLFGTQVEDFSTFSNCIFTQFRIILGDFDFNAIENANRVLGPLYFTTYVFVVFFVLLPKNMFLAIINDTYAEVKNELAEKENEFDVGGYFKKVYLDIRKKLGKNRGNIVDMI-SVLDA---SSQKINYDDWRLKLKRLGHSDEEIEAAFAKFDKDKNSVLDSNE 673
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BLAST of PKD2-2 vs. Ensembl Sea Lamprey
Match: pkd2 (polycystic kidney disease 2 [Source:NCBI gene;Acc:432387])

HSP 1 Score: 307.76 bits (787), Expect = 2.639e-92
Identity = 218/739 (29.50%), Postives = 367/739 (49.66%), Query Frame = 3 
Query:  429 SLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKS-FTTVSTISNVWQ----YLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSC-EIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSR-NKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYE-FWNWLDIVVIIISLVCAIFDIYRTASVQKLI-QGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGD----------RTLNLNEQXXXXXXXXXXXXXXXXXXXXTKQF-------------------NGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEG---IDEDERRNQIHNIINSELEKYN 2522
             LWAT+ TE    NRE Y+K  +RE + + VFL +L ++A+     + + YT A+  +F      + + + F  ++TI  VWQ    YL GP L  L+     N         +V  EN ++    I Q +V NNSC  +          CY  +SS NE+K+ FG  NST W + S   +   G       Y  GG+   L   ++T   Q L +L + SW+   TR++ +D  L NPN+ L+ V+RL  EFP  GG+ T+      + L     +D   A C ++  L  +YY+VEE +E+R    A F    W +LDI +I + +V   F ++       L+ +   S    F     ++  +Q F     + +F+AWIK+ ++ S  +T+T     LTR + DL G+ ++F  +F AFA+L + IFG  + DF +     LTQ RI+LGDFD+  LE+A RI+GP+YF+ + F V  +++ MFLAI+++ Y+E K+E A  + +F+++   +     V+  L  K+ ++  IQ       +    ++++  WR  LK +G+ADAEIE+VF +YD DG           R L L +Q          +E  +K    ++                      G +       +  +E+ +L RRV++ME +I  +V K+D ++     +++ ++ +  V+S L+  +   E      ++ RR+ +  ++  EL++++
Sbjct:    1 GLWATRWTESPVLNRERYVKLAIREAVTFSVFLALLCVVAYSSRIPLAYEYTHAVSEMFTSSPLSNADPTTFHNLATIEQVWQVFHGYLTGPLLWALH-----NSGSRNLTNSMVSGENLVVEPVIIWQARVHNNSCWSLSTNLGTGTTECYGPYSSANENKDPFGPANSTVWRFDSEAGVPWQGALGW---YGPGGYAVRLPADSRTAAWQELAALRDASWLDRATRLLSVDAALLNPNLRLYMVVRLSMEFPPTGGILTALSLTPGRPLG-TPLWDAR-AVCGLLAALLTIYYLVEEVLELRNLGPAGFLSSPWTFLDISIIALCVVGTAFGVHHGILSSSLLGEASSSRAMSFSTVSTVAEWEQNFIIVTGVIVFVAWIKVVRFGSMCRTLTMCGCALTRCAWDLLGYTLVFATVFLAFAQLAFLIFGGALPDFSSFSSCILTQVRILLGDFDFSSLEAASRIMGPIYFVSYVFCVGLIMMVMFLAIVSEAYSEEKSEQAHSQPQFQLSSVIKQV--KVVDRLSCKKPRVAGIQK-----TLPPSGQINFATWRQNLKGQGFADAEIEAVFARYDGDGALTRAEQLQMRRDLRLEKQTIRLHISVSPREKKKKHQVTSRDDDDDDDDGDSDEDDDITVVRRGNHHQGGGGGVSREEFRVLVRRVNQMEHSIGSVVSKMDAVMVKLEAMERQRLRRRDVLSRLISGMGEEERGSWPGQEVRRDHMERLVRDELKRWD 722
[Close]
BLAST of PKD2-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007306.1 (pep scaffold:Pmarinus_7.0:GL480012:400827:419749:1 gene:ENSPMAG00000006595.1 transcript:ENSPMAT00000007306.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 85.5001 bits (210), Expect = 4.115e-17
Identity = 95/475 (20.00%), Postives = 202/475 (42.53%), Query Frame = 3 
Query:  495 VRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDIT--DDTDLVYYENQILGIPRIRQLKVRNNSCEI----PKVFQGDMKHCYSEFSSENEDKNNFGLNNSTA----WIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEF-RVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTY 1886
            VR+LI++++   +L+ I +   D   F    +++  F+   FD                      FL   Y   WYNG+ ++  +   L  +    +G  R+RQ++    +  +    P       +  Y   +  N+           A     I++   +     +    + Y  GGF  +L  N     +++ +L   SW+   TR +  +FT YN N +LF  + L+ EF    G    + +  V ++  ++   +       ++F + +V     E + + +  +AYF  FWN  +++ I +     +    + +   + ++   ++ ++F  F  L    QQ +  +A  +F++ IK+  ++   +    L    + +   + GFAV+  ++F +F +L   +F   + ++          F ++LG   Y +L +A+R++GP+ +  FT    FV++N  L I+++ +
Sbjct:  612 VRQLILFLMHAALLVFITYRGRDPYAFLVQNSVRNAFVLNSFDHNG-------------------FLPNFYPRAWYNGERMSWRERYYLRDFSTIRVGPGRLRQIRSVPRAWNLLLSAPTAVATLSRAPYVVAARANQRCGEGTTQRKRAVRQYQIFSHRVTQLVPVWHPSLALYSGGGFIAELGLNLADGTEIVANLSSASWLDHSTRAVLTEFTGYNMNTDLFCSVTLLLEFSQGAGDAHGHAYIHVFRIESFVGKLETLTGVVYIVFAILLVIIAATEALRLSELGVAYFKSFWNIAELLSITLGAASVVTYFIKMSVATRTLEKFRTDPHKFVNFQELVTWDQQLSELLATLVFVSTIKVLGHMKSLRQFEVLVGAFSEARDHIQGFAVIVVVVFCSFGQLTSLLFAGSLRNYRTFTTCLEQLFSLLLGQPGYGELYAANRVLGPLIYFAFTSVNTFVIVNFSLGILSEGF 1067
[Close]
BLAST of PKD2-2 vs. Ensembl Nematostella
Match: EDO47023 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN85])

HSP 1 Score: 613.224 bits (1580), Expect = 0.000e+0
Identity = 328/677 (48.45%), Postives = 467/677 (68.98%), Query Frame = 3 
Query:  201 FQMHNYGMNKSRPPTADSRRVLWNDEDYVESEHMD----NEPTAMEDQHQ--IENVYKTQAVTEEQKYSSN-----------GCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDIT---DDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQ 2171
             +MH     KS  P + + R  W+++D +  +  D    + P A        + +  + + V+ +++ +++           GCW +FKRI+R LW T+ TEDT  +RE++IKTT+RELIIY+VF+TIL I+ FGM     +Y+TK ++ LF++    ++  +F  ++T++  W Y      +GLYW+++YN Q++T   DD   +Y+EN+ILG PR RQL+V N+SC +   F+  +K CY+ +S   ED N FG  N +AW Y + + L    Y+   + Y  GGF Q L+  K  T Q++  L +N W+  GTR +FIDFT+YN NINLF ++RL+FE+P  GG   S  FR VKL+RY+ TFD+F+ ACE IF LFI+YY +EE +EI+KHK+ YF  FWN LD+VVI++  V  +F++YRT +V  L+  LL + +Q+  FD L + Q QFNN VA+ +F AWIK+FKYISFNKTMTQLSSTL++ +KD+ GFA+MFFIIFFA+A+LGY IFG+Q+ DF     S  T FRIILGDFD+ Q+E+A+R++GP++F+ + FFVFFVL+NMFLAII DTYAEVK++IA+Q++EFE+ DYF+   +N+L  L FK++KI DIQ A+ +AD+N D KLD++EWR  LKSRG+ADAEIE+VF KYD DGDR L+ +EQ
Sbjct:    5 MEMHE----KSGRPASSNSRAAWSEDDLLTGQGGDEIDFSSPRAPASAAVDVMPSAMEAEPVSHQKRIAADVRVPGAKNVPVGCWTRFKRIIRGLWRTRQTEDTDSDREMHIKTTLRELIIYLVFITILCILTFGMTSSTMYYFTKVMRDLFVESSMSNR-NTFKDITTMNEFWMYTTETLSDGLYWEQYYNNQNVTKPKDDLGFIYFENKILGRPRFRQLRVLNDSCTVHDDFKSVIKECYAAYSPNVEDMNTFGKMNGSAWTYQTEKDLQGRSYWGRMTTYSGGGFTQLLAPTKAETQQIIEDLKQNLWLDRGTRAVFIDFTVYNANINLFCIVRLVFEYPPTGGCIPSFNFRTVKLIRYVDTFDHFVMACEGIFILFIIYYTIEEGLEIKKHKMKYFKSFWNVLDVVVIMLGYVAVVFNLYRTMAVGDLLSSLLEDGSQYANFDSLGFWQTQFNNMVAVAVFFAWIKVFKYISFNKTMTQLSSTLSKCAKDVAGFAIMFFIIFFAYAQLGYLIFGTQVRDFSTFEDSIFTLFRIILGDFDFHQIENANRVLGPLFFMTYVFFVFFVLLNMFLAIINDTYAEVKSDIASQESEFEITDYFKKGYQNMLNKLSFKREKILDIQKALKSADVNQDNKLDFEEWRANLKSRGHADAEIEAVFAKYDLDGDRILDEDEQ 676
[Close]
BLAST of PKD2-2 vs. Ensembl Nematostella
Match: EDO49200 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHB8])

HSP 1 Score: 223.402 bits (568), Expect = 3.161e-60
Identity = 163/511 (31.90%), Postives = 255/511 (49.90%), Query Frame = 3 
Query:  471 RELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLF--LDEK---FDDKEKSFTT--VSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYE---NQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFG-----LNNSTAWIYTSPESLNSS-----GYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADY 1943
            +E+ +   ++E++ Y +F+ +L+++A+G  D   +   K L   F  LDE     D+ +    T  V    ++W +     +  LY    YNG+    D    Y E   N ++GI R+R  +V+N SC IPK        CY EFS  N D +++      LN S A       S+         Y+   + Y  GG+  DL  +    L ++  L  ++WV   TR +FI+F +YN N NLF V  L  EF   GG     EF+V +L  Y+  F  F+ A EVI  LF+ Y++  E   + K K  YF  FWNWL++ +I++  +       R   V K    L  N   F +F +     +  N  + I +F   I+  K + FN+ M  L +T+   +K +  F + F ++F +FA  G  IFG  ++ F +   + +TQ  I LGDFDY ++E  +R++G +YF  F +F+   L+NMFLAII D+++EVK      KNE+EM ++
Sbjct:  606 KEIQMSMILKEILAYFIFIAVLLLVAYGNRDPNAYLLRKTLVEEFVSLDESGVSLDEVQWKNGTIIVGDGDSLWHWARETLIKNLYPGNLYNGKP---DKYTGYLEDRVNYLVGISRLRLERVKNGSCTIPKEMDRFFDECYGEFSYSNSDSDDYEVEWMFLNKSAAPSARKRRSIAEQFSFGFPYWGKMNFYSGGGYPADLGYDYPTALTVVADLHSHNWVNSNTRGVFIEFAIYNANTNLFGVAFLYVEFLPTGGAFPHGEFKVARLYSYVGPFANFVLAMEVIMLLFMFYFVYREVKSMYKLKKKYFKGFWNWLEVAMIVLEFLMLGLFFARMWEVDKNFIELHHNPKDFVSFQYALASDETLNYVIGILVFFVTIRFIKLLRFNRRMALLGNTIALIAKPIGQFLISFTLVFISFAFFGNMIFGIGLDKFRSFTTTMMTQLNICLGDFDYLEMEEENRMLGRIYFFSFMYFIVMYLMNMFLAIINDSFSEVKTSNDDLKNEYEMVEF 1113
[Close]
BLAST of PKD2-2 vs. Ensembl Nematostella
Match: EDO44884 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUD7])

HSP 1 Score: 213.386 bits (542), Expect = 4.856e-57
Identity = 150/521 (28.79%), Postives = 259/521 (49.71%), Query Frame = 3 
Query:  468 NRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKE-----KSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNF------------GLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLS-NENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQL 1976
            ++E  +   + ++  Y+ FL +L++IA   +D   ++ ++++  + +   ++        K+F  +S  S +W +     L  LY   WY     T    +      ++G  R RQL+ + ++C I  V +G + HC   +S   +D+ N+              + ST W + S   LN   YF   S Y  GG+    S      ++ ++    NSW+   T  +F +FTLYNP  NLF+   ++ E    GG     EF   +L   +  F  F   C+V+F LF  Y+   E  ++ K K +YF ++WNW +IV+++++ + A+ D +    ++K    L   N N +  F ++S  Q  F + + I +FI+ IK  K + FNK M  L+ TL+RS+KDL  + +MF I+F +FA+  Y + GS  + F   +KS      ++LG F +++     RI+G   F L+     F+L+NMF+AII +++ EVK      +NEFE+ ++     R VL +
Sbjct:  543 DKERKMSVILTDIGTYLTFLWVLLVIAHSRVDSAAYWQSRSISDVLMKTTYESPPESGLTKTFQKISNDSEIWLWTNHVLLPALYNLDWYYYTK-TAPKLVRGGAGLVVGFARWRQLRKKKDTCLITGVMRGVIHHCTDPYSMSTQDETNYNSRWRPFNTSDVPPSPSTIWSFNSASKLNGYPYFGEISTYSGGGYIVPFSSIYYKAVKEIKHARNNSWIDRYTAGLFTEFTLYNPYSNLFTASTVLVEVLPTGGFHVRPEFFTFRLYSLVGDFHIFTLVCDVVFLLFTSYFTFRELKKLYKDKCSYFRDYWNWAEIVIMVLAWI-AVADYFICLGIRKWTLKLHQENPNDYTNFQYISAWQMSFESILGILVFISTIKFIKLLRFNKKMFLLAYTLSRSAKDLAHYGIMFLIVFLSFAQFYYLLLGSDYDSFSTFVKSIEKLINVLLGRFSFEEFLIPFRIMGAFGFFLYMTLTNFLLLNMFIAIIVESFTEVKLSPELARNEFEIMEFTVERVREVLGI 1061
[Close]
BLAST of PKD2-2 vs. Ensembl Nematostella
Match: EDO40051 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8E5])

HSP 1 Score: 200.675 bits (509), Expect = 1.248e-55
Identity = 140/502 (27.89%), Postives = 266/502 (52.99%), Query Frame = 3 
Query:  471 RELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDI----TDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLN---NSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQ----DLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADY 1943
            +E  + + +RE++ Y++FL I++ I++G  D  T   T  ++ +FL   ++   K F  + +  + W +L    +  ++ ++WYN QD       DT   +    +L + R+RQL+++ ++C +    Q  +  C   +SS+ E++           TAW Y + E L +  Y+   + Y  GG+ Q      ++N      +  +L EN W+   TR +F +F++YN N NLF V+ L+ E    GG+        ++L RY+    +F+AACE+I+ LF  Y+I  E  +  K  L      W+ L+I V  +SL   +    R     ++++ + ++  +F +  + ++  +     + + +F ++IKI + + FN+ M+ L+ TL      +  F +++ I FFA+A+L   +FG   E F  + +SA T    +LG F  +++   +R+IGP +F ++T  + F+LINMF++II D++AEV ++++ Q N++E+ D+
Sbjct:    1 QERQMASIMREIVWYLIFLFIVLSISYGNRDPYTQLVTNNVENVFLQASYNGSTK-FDEIGSTRDYWPWLKDTVIPSIFIEKWYNDQDYHLGYLADTPTAW----VLAVARLRQLRMQKHTCPLLPALQHVIPSCNDFYSSDEEERGMLLPGWKEPKTAWQYQTGEELKTFPYWGQKATYSAGGYVQVFPPSTAKNYDKAQALADALNENDWLDKYTRAVFTEFSIYNANSNLFCVVTLLIEQLPTGGIFKFPSILTLRLYRYVGGEMFFVAACEIIYLLFTAYFIFREIKQAYKLGLDKLKNPWSILEIFVTCLSLSMVVLYFLRIKFTAEVVKDMRNDPTRFVSLHYTAFLDEWIKCLMGLIVFFSFIKIVRLLRFNRRMSLLAQTLKLCIPKIGAFVIVYGIAFFAYAQLACLVFGQNAEGFMTIPRSAATLMDTLLGKFTLKEMSDINRLIGPTFFYIYTLSMIFILINMFMSIINDSFAEVNSDVSKQANDYEIVDF 497
[Close]
BLAST of PKD2-2 vs. Ensembl Nematostella
Match: EDO44744 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUR6])

HSP 1 Score: 205.682 bits (522), Expect = 1.816e-54
Identity = 150/511 (29.35%), Postives = 256/511 (50.10%), Query Frame = 3 
Query:  492 TVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLF-----LDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTD-LVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNF--------GLNNSTA---WIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAY-FYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVL 1970
             ++E++ Y +F+ +++++A+G  D       + L+ +F      D    D       VS I++ W +     + GLY + WYNG+  +D    L  + + +LG  R+RQL+V+   C++  V+ G +  C   +S + ED              N STA   W Y     L S  Y    + Y  GG+  DL + K   + ML  L  + WV   TR IF++FT+Y+P  NL  V  L+ E    GG    +E  V ++ RY   F  F+  CE++F LF VY+  ++  EI +  +AY F+E+W+W+++V+   S    +    R    +  +     + + F  F  L+   Q F    A   F   +K  +   FNK M+ L++TL  S+K+L  F+++F ++F AF    Y IF +++  F  ++ +  T   ++LG F Y++L   +R++ P  F  ++  V F+LINMF++II + +  VK++   Q NE+E+ D+     R+ L
Sbjct:  610 VIQEILFYALFVWVVLVVAYGHRDPNAHVMNQGLEDVFSGRAKHDHSVPDGHSLLFQVSDITSFWNWTEAVLIPGLYSESWYNGR--SDKPGFLADHTSWMLGTARMRQLRVKAGDCKVHDVYSGYLAQCNGPYSWDTEDTTPVFRPGWRPAPSNYSTAQNAWKYRDSSELRSLPYLGKLALYSGGGYAFDLGK-KEKAMAMLAQLKRDKWVDRSTRAIFVEFTVYSPYTNLHCVGYLLLEVLPSGGTSPFSELLVTRIDRYAGNFMIFVLLCEILFVLFTVYFTYKQGKEIAREGVAYHFHEYWSWVELVLSGCSWTSIVLYFVRFGINKSTVLTYHKDTSVFVNFHALAASDQVFGYVYAFVAFFVSLKFLRLFRFNKRMSLLATTLKCSAKELAHFSIVFGLVFMAFVHFCYLIFSTELYIFHTVLSTVETLISVMLGKFSYERLLQTNRLLAPFMFFFYSIVVVFILINMFISIIIENFQRVKSQNDLQSNEYEIVDFMTEQFRDWL 1117
[Close]
BLAST of PKD2-2 vs. Ensembl Medaka
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:100192346])

HSP 1 Score: 546.584 bits (1407), Expect = 2.530e-180
Identity = 306/779 (39.28%), Postives = 484/779 (62.13%), Query Frame = 3 
Query:  345 NVYKTQAVTEEQ--KYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFD-DKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNE-QXXXXXXXXXXXXXXXXXXXXTKQFNGENSDYNKTNIDI----------------------DEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE--GIDEDERRNQIHNIINSELEKYNYSDTISIGNVSSASRPGTARSTRKD 2597
             +Y TQ +  +Q  ++   GC  +  + +R LW T+L ED   NRE Y+   +REL+ Y+ FL  + I+ +GMI    +YYTKA+  LFLD     +  K+F ++ST+ + W+Y  GPFL G+YW+ WYN Q +  +   +YYEN +LG+PR+RQ++V N +C I +  + +++ CY  ++  NED + FG  N TAW++T+   +N+S ++   S+Y  GG+YQDLSR +  +   L+ L ++ W+  GTR IF+DF++YN N+NL  + RL+ EFP  GGV TS +F+ V+L++Y+S++DYF+  CEV FCLF++YY+VEE +EI  H+L YF   WN LD++++ +S+V  I  I R A    L++G L N     +FD L+  Q QFNN  A+ +F  W+K+FK+I+FNKTM+QLS+T++R +KDL GFA+MFFIIF A+A+L Y +FG+Q+ DF     S  TQFRIILGDFD+ +++ A+ ++GP+YFI F  F+FF+L+NMFLAII DTY+EVKA++A  ++E EM D+ +      L  L+ K+  + DI D++  A      KL+YDE   +LK +G+ +AEI+++F KYD+DGD  L  ++ Q+  +      ++L  +    T+  +G +    + + +                       +E+ +L RRVDRME +I  IV K+D ++     +++ K+ +  V+  LL+ +   E  G D D  R Q+  ++  ELE++   D   + + ++++R  T   T +D
Sbjct:  111 GLYPTQTLNGQQQDRHEHPGCMKRIFQNIRILWGTELMEDGDSNRERYLWNVLRELLTYIAFLITICILTYGMISTNMYYYTKAMSQLFLDAPLSSENPKTFRSLSTMEDFWKYTQGPFLGGMYWEVWYNNQSLPGNQSFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQGCYGVYTPSNEDNSPFGPQNGTAWVHTTESKMNASTHWGQVSKYGGGGYYQDLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGVLTSWQFQTVRLIKYVSSWDYFVGVCEVAFCLFVLYYVVEEVLEIHIHRLHYFKNLWNCLDVLIVTLSVVAIIMSITRAAMGGDLLKG-LENYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQGSVFTQFRIILGDFDFFEIKEANPVLGPIYFITFVLFIFFILMNMFLAIINDTYSEVKADMAQHRSEMEMTDFIKKGCTKALVKLRLKKTTVDDISDSLRQA----GGKLNYDELLQDLKEKGHTEAEIQAIFAKYDQDGDLELTEHDHQQMRDDLEKEREDLDLERNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEGMERAKLKRRDVLVRLLDGVMEDERLGRDADTHREQMERLVKEELERWETDD---VASQTASTRALTEEPTCED 881
[Close]
BLAST of PKD2-2 vs. Ensembl Medaka
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:100192346])

HSP 1 Score: 545.428 bits (1404), Expect = 3.652e-179
Identity = 303/760 (39.87%), Postives = 474/760 (62.37%), Query Frame = 3 
Query:  345 NVYKTQAVTEEQ--KYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFD-DKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNE-QXXXXXXXXXXXXXXXXXXXXTKQFNGENSDYNKTNIDI----------------------DEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE--GIDEDERRNQIHNIINSELEKYNYSDTIS 2540
             +Y TQ +  +Q  ++   GC  +  + +R LW T+L ED   NRE Y+   +REL+ Y+ FL  + I+ +GMI    +YYTKA+  LFLD     +  K+F ++ST+ + W+Y  GPFL G+YW+ WYN Q +  +   +YYEN +LG+PR+RQ++V N +C I +  + +++ CY  ++  NED + FG  N TAW++T+   +N+S ++   S+Y  GG+YQDLSR +  +   L+ L ++ W+  GTR IF+DF++YN N+NL  + RL+ EFP  GGV TS +F+ V+L++Y+S++DYF+  CEV FCLF++YY+VEE +EI  H+L YF   WN LD++++ +S+V  I  I R A    L++G L N     +FD L+  Q QFNN  A+ +F  W+K+FK+I+FNKTM+QLS+T++R +KDL GFA+MFFIIF A+A+L Y +FG+Q+ DF     S  TQFRIILGDFD+ +++ A+ ++GP+YFI F  F+FF+L+NMFLAII DTY+EVKA++A  ++E EM D+ +      L  L+ K+  + DI D++  A      KL+YDE   +LK +G+ +AEI+++F KYD+DGD  L  ++ Q+  +      ++L  +    T+  +G +    + + +                       +E+ +L RRVDRME +I  IV K+D ++     +++ K+ +  V+  LL+ +   E  G D D  R Q+  ++  ELE++   D  S
Sbjct:  111 GLYPTQTLNGQQQDRHEHPGCMKRIFQNIRILWGTELMEDGDSNRERYLWNVLRELLTYIAFLITICILTYGMISTNMYYYTKAMSQLFLDAPLSSENPKTFRSLSTMEDFWKYTQGPFLGGMYWEVWYNNQSLPGNQSFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQGCYGVYTPSNEDNSPFGPQNGTAWVHTTESKMNASTHWGQVSKYGGGGYYQDLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGVLTSWQFQTVRLIKYVSSWDYFVGVCEVAFCLFVLYYVVEEVLEIHIHRLHYFKNLWNCLDVLIVTLSVVAIIMSITRAAMGGDLLKG-LENYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQGSVFTQFRIILGDFDFFEIKEANPVLGPIYFITFVLFIFFILMNMFLAIINDTYSEVKADMAQHRSEMEMTDFIKKGCTKALVKLRLKKTTVDDISDSLRQA----GGKLNYDELLQDLKEKGHTEAEIQAIFAKYDQDGDLELTEHDHQQMRDDLEKEREDLDLERNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEGMERAKLKRRDVLVRLLDGVMEDERLGRDADTHREQMERLVKEELERWETDDVAS 865
[Close]
BLAST of PKD2-2 vs. Ensembl Medaka
Match: pkd2l1 (polycystin 2 like 1, transient receptor potential cation channel [Source:NCBI gene;Acc:100820724])

HSP 1 Score: 506.523 bits (1303), Expect = 4.393e-166
Identity = 302/762 (39.63%), Postives = 475/762 (62.34%), Query Frame = 3 
Query:  210 HNYGMNKSRPPTADSRRVLWNDEDYVESEHMDNEPTAME--------DQHQIENVYKTQAVTEEQKYS------SNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITD-DTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXX-----------XXXXTKQF--NGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQS 2411
            H  G   S P    +    W +  Y ES     EP  +          Q  +++ Y   A  +  + S       +GC       ++ LW T LTE+   NRE YI+TT+REL++Y++FL  + ++ +GM    T+Y+TKA+  LF++    D   +F ++ T+++ W +  GP L+GLYW +WYN Q + + +   +YYEN +LG+PR+RQ+K++NNSC++ + F+ ++  CY  +  + ED  NFGL N TAW Y + + +  S ++ L S Y   G+YQDL R +  + ++L +L +N W+  GTRV+FIDF+ YN NIN+F V+ L+ EFP  GG   S + R VKLLRY++ +DYFI  CE +FC+FI+YY+VEE +E+R H+ +Y    WN LDIVVI+++LV   F+++RT  V  L+  LL N N +  F+FL++ Q Q+NN  A+NLF AWIKIFKYISFNKTMTQLS+TL R +KD+ GFAVMFFI+FFA+A+LGY +FG++++ F   +K   TQFRIILGDF++  ++ A+R++GP+YF+ + FFVFFVL+NMFLAII DTY+EVK E+ +QK+E ++ D  + +       L+ K+ KI D+Q A+         ++ + +++  L   G+ D EI + F K+D+DG++ L+  EQ+ ++ EL  +++ +             +  ET+ F  + + S  N+T +D  ++  L R+V +++ +++DI  +++ +L      +K K  +S
Sbjct:   11 HLSGQVGSEPGAVGTGG--WVNHGYCESP----EPPGVSTIYGPRPAPQGPVDSPYSLDAAGKFPEASVQRVKKKSGCC----SFIKGLWGTALTENVSNNREKYIRTTLRELLVYLLFLLDICLLTYGMTSSSTYYFTKAMTDLFVNSG-GDAGVAFQSIGTMADFWSFAQGPLLDGLYWTKWYNQQSLNNGNQSFIYYENMLLGVPRMRQIKMKNNSCKVHQDFKDEIFGCYDVYDEKKEDDLNFGLINGTAWTYHTEKEMRGSSHWGLLSTYSGAGYYQDLDRTRERSAEILSTLMDNCWLGRGTRVVFIDFSAYNANINMFCVISLMVEFPATGGAVPSYQIRTVKLLRYVTRWDYFILGCEAVFCVFILYYMVEEVLELRIHRFSYLKSVWNILDIVVILLALVAIAFNVFRTIKVDNLLGKLLENPNIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSTTLGRCAKDILGFAVMFFIVFFAYAQLGYLLFGTEVDTFSTFVKCIFTQFRIILGDFNFDAIDQANRVLGPIYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELTSQKDELQITDIIKQSYMKTFTRLKLKKDKITDVQKALQAG----SGEIQFKDFKQTLIEMGHTDGEISAAFSKFDRDGNQVLDAEEQERMKRELQEKRDALSTELNHLGKNYEKEPVETESFPPHEQRSVSNQTFVDQQQFQSLARQVLQVQRSVADITSRMELILAQMGLQEKAKGGES 757
[Close]
BLAST of PKD2-2 vs. Ensembl Medaka
Match: pkd2l1 (polycystin 2 like 1, transient receptor potential cation channel [Source:NCBI gene;Acc:100820724])

HSP 1 Score: 505.368 bits (1300), Expect = 5.628e-164
Identity = 302/762 (39.63%), Postives = 475/762 (62.34%), Query Frame = 3 
Query:  210 HNYGMNKSRPPTADSRRVLWNDEDYVESEHMDNEPTAME--------DQHQIENVYKTQAVTEEQKYS------SNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITD-DTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXX-----------XXXXTKQF--NGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQS 2411
            H  G   S P    +    W +  Y ES     EP  +          Q  +++ Y   A  +  + S       +GC       ++ LW T LTE+   NRE YI+TT+REL++Y++FL  + ++ +GM    T+Y+TKA+  LF++    D   +F ++ T+++ W +  GP L+GLYW +WYN Q + + +   +YYEN +LG+PR+RQ+K++NNSC++ + F+ ++  CY  +  + ED  NFGL N TAW Y + + +  S ++ L S Y   G+YQDL R +  + ++L +L +N W+  GTRV+FIDF+ YN NIN+F V+ L+ EFP  GG   S + R VKLLRY++ +DYFI  CE +FC+FI+YY+VEE +E+R H+ +Y    WN LDIVVI+++LV   F+++RT  V  L+  LL N N +  F+FL++ Q Q+NN  A+NLF AWIKIFKYISFNKTMTQLS+TL R +KD+ GFAVMFFI+FFA+A+LGY +FG++++ F   +K   TQFRIILGDF++  ++ A+R++GP+YF+ + FFVFFVL+NMFLAII DTY+EVK E+ +QK+E ++ D  + +       L+ K+ KI D+Q A+         ++ + +++  L   G+ D EI + F K+D+DG++ L+  EQ+ ++ EL  +++ +             +  ET+ F  + + S  N+T +D  ++  L R+V +++ +++DI  +++ +L      +K K  +S
Sbjct:   11 HLSGQVGSEPGAVGTGG--WVNHGYCESP----EPPGVSTIYGPRPAPQGPVDSPYSLDAAGKFPEASVQRVKKKSGCC----SFIKGLWGTALTENVSNNREKYIRTTLRELLVYLLFLLDICLLTYGMTSSSTYYFTKAMTDLFVNSG-GDAGVAFQSIGTMADFWSFAQGPLLDGLYWTKWYNQQSLNNGNQSFIYYENMLLGVPRMRQIKMKNNSCKVHQDFKDEIFGCYDVYDEKKEDDLNFGLINGTAWTYHTEKEMRGSSHWGLLSTYSGAGYYQDLDRTRERSAEILSTLMDNCWLGRGTRVVFIDFSAYNANINMFCVISLMVEFPATGGAVPSYQIRTVKLLRYVTRWDYFILGCEAVFCVFILYYMVEEVLELRIHRFSYLKSVWNILDIVVILLALVAIAFNVFRTIKVDNLLGKLLENPNIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSTTLGRCAKDILGFAVMFFIVFFAYAQLGYLLFGTEVDTFSTFVKCIFTQFRIILGDFNFDAIDQANRVLGPIYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELTSQKDELQITDIIKQSYMKTFTRLKLKKDKITDVQKALQAG----SGEIQFKDFKQTLIEMGHTDGEISAAFSKFDRDGNQVLDAEEQERMKRELQEKRDALSTELNHLGKNYEKEPVETESFPPHEQRSVSNQTFVDQQQFQSLARQVLQVQRSVADITSRMELILAQMGLQEKAKGGES 757
[Close]
BLAST of PKD2-2 vs. Ensembl Medaka
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:100192346])

HSP 1 Score: 478.404 bits (1230), Expect = 2.328e-154
Identity = 278/778 (35.73%), Postives = 448/778 (57.58%), Query Frame = 3 
Query:  345 NVYKTQAVTEEQ--KYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFD-DKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNE-QXXXXXXXXXXXXXXXXXXXXTKQFNGENSDYNKTNIDI----------------------DEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTE--GIDEDERRNQIHNIINSELEKYNYSDTISIGNVSSASRPGTARSTRK 2594
             +Y TQ +  +Q  ++   GC  +  + +R LW T+L ED   NRE Y+   +REL+ Y+ FL  + I+ +GMI    +YYTKA+  LFLD     +  K+F ++ST+ + W+Y  GPFL G+YW+ WYN Q +  +   +YYEN +LG+PR+RQ++V N +C I +  + +++ CY  ++  NED + FG  N TAW++T+   +N+S ++   S+Y  GG+YQDLSR +  +   L+ L ++ W+  GTR IF+DF++YN N+NL  + RL+ EFP  GGV TS +F+ V+L++Y+S++DYF+  CEV FCLF++YY+VEE +EI  H+L YF   WN LD++++ +S+V  I  I R A    L++G L N     +FD L+  Q QFNN  A+ +F  W+K+FK+I+FNKTM+QLS+T++R +KDL GFA+MFFIIF A+A+L Y +FG+Q+ DF         Q  +   D  Y         + P++F+          +++F          VKA++A  ++E EM D+ +      L  L+ K+  + DI D++  A      KL+YDE   +LK +G+ +AEI+++F KYD+DGD  L  ++ Q+  +      ++L  +    T+  +G +    + + +                       +E+ +L RRVDRME +I  IV K+D ++     +++ K+ +  V+  LL+ +   E  G D D  R Q+  ++  ELE++   D   + +  S  +P T    R 
Sbjct:  111 GLYPTQTLNGQQQDRHEHPGCMKRIFQNIRILWGTELMEDGDSNRERYLWNVLRELLTYIAFLITICILTYGMISTNMYYYTKAMSQLFLDAPLSSENPKTFRSLSTMEDFWKYTQGPFLGGMYWEVWYNNQSLPGNQSFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQGCYGVYTPSNEDNSPFGPQNGTAWVHTTESKMNASTHWGQVSKYGGGGYYQDLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGVLTSWQFQTVRLIKYVSSWDYFVGVCEVAFCLFVLYYVVEEVLEIHIHRLHYFKNLWNCLDVLIVTLSVVAIIMSITRAAMGGDLLKG-LENYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTF------QGSVSRTDLLYN--------LRPLHFLYSHGEKGICTVSLF----------VKADMAQHRSEMEMTDFIKKGCTKALVKLRLKKTTVDDISDSLRQA----GGKLNYDELLQDLKEKGHTEAEIQAIFAKYDQDGDLELTEHDHQQMRDDLEKEREDLDLERNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEGMERAKLKRRDVLVRLLDGVMEDERLGRDADTHREQMERLVKEELERWETDD---VASQVSHPQPATPIGPRP 856
[Close]
BLAST of PKD2-2 vs. Planmine SMEST
Match: SMESG000033381.1 (SMESG000033381.1)

HSP 1 Score: 1439.86 bits (3726), Expect = 0.000e+0
Identity = 764/792 (96.46%), Postives = 764/792 (96.46%), Query Frame = 3 
Query:  222 MNKSRPPTADSRRVLWNDEDYVESEHMDNEPTAMEDQHQIENVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTKQFNGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEGIDEDERRNQIHNIINSELEKYNYSDTISIGNVSSASRPGTARSTRKD 2597
            MNKSRPPTADSRRVLWNDEDYVESEHMDNEPTAMEDQHQIENVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFIVYYIVEETIEIRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLFGFAVMFFIIFFAFAELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGP                            VKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQKNLEGELNIEKELIEKDIEETKQFNGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEGIDEDERRNQIHNIINSELEKYNYSDTISIGNVSSASRPGTARSTRKD
Sbjct:    1 MNKSRPPTADSRRVLWNDEDYVESEHMDNEPTAMEDQHQIENVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFIVYYIVEETIEIRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLFGFAVMFFIIFFAFAELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGP----------------------------VKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQKNLEGELNIEKELIEKDIEETKQFNGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEGIDEDERRNQIHNIINSELEKYNYSDTISIGNVSSASRPGTARSTRKD 764
[Close]
BLAST of PKD2-2 vs. Planmine SMEST
Match: SMESG000033381.1 (SMESG000033381.1)

HSP 1 Score: 1205.28 bits (3117), Expect = 0.000e+0
Identity = 653/681 (95.89%), Postives = 653/681 (95.89%), Query Frame = 3 
Query:  555 MIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTKQFNGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEGIDEDERRNQIHNIINSELEKYNYSDTISIGNVSSASRPGTARSTRKD 2597
            MIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFIVYYIVEETIEIRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLFGFAVMFFIIFFAFAELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGP                            VKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQKNLEGELNIEKELIEKDIEETKQFNGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEGIDEDERRNQIHNIINSELEKYNYSDTISIGNVSSASRPGTARSTRKD
Sbjct:    1 MIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFIVYYIVEETIEIRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLFGFAVMFFIIFFAFAELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGP----------------------------VKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQKNLEGELNIEKELIEKDIEETKQFNGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEGIDEDERRNQIHNIINSELEKYNYSDTISIGNVSSASRPGTARSTRKD 653
[Close]
BLAST of PKD2-2 vs. Planmine SMEST
Match: SMESG000018492.1 (SMESG000018492.1)

HSP 1 Score: 647.506 bits (1669), Expect = 0.000e+0
Identity = 356/714 (49.86%), Postives = 495/714 (69.33%), Query Frame = 3 
Query:  312 PTAMEDQHQIENVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDITDD-TDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTK-QFNGENSDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNN 2447
            P+AM D           ++ E    + N CW +FK  +RSLWAT+ TEDT  +R+LYIKTT+REL+IY+ FL +L+II+FGM     +++T  L  LF    F+D   +F   +T S+ W++L GP LNGLYW  WYN  + T D  + +YYEN+++G+PR+RQ++VRN+SC IP  FQG++K C++ +S  +E K+++G  NST W+YT+   L+++ Y  + + Y  GGFY +L+  +  +   + +LF N W+  GTR + IDFT+YN NINLF  ++L+ EFP  GG+  S++FR VKL+RY+ + D+F+ ACE++F +FIVYYIVEE++EI+  K  YF+  WN LDI+VII SL C+IF+I RT +VQ +IQ L++N+N  P F+ L++ Q QF+N +AI LF+AW+K+FKYISFNKTMTQLS+TL+R SKDL GFA+MFFIIF AFA+LGY IFG+Q+ DF  L     T FRIILGDFD+ QLE AHRI GP+YF+ + FFVFFVL NMFLAIITDTY EVK E+A QKNEFE+ADY +     VL  L  K+ KI DIQ+A+L  D N+D K+D+DEWR ELKSRGY DAEIE+VF +YD DGD+ L+  EQ  ++ EL  +K  ++ +I+  K +   +  D     + ++EY  L RRVDRM+ N   IV K+D +L+    ++K K    + +  +L  LN+
Sbjct:   13 PSAMSDDSYEYGKSTKDSIEETNFINPNSCWNRFKNGIRSLWATRHTEDTKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNFNDNSGTFAASTTESDFWKFLTGPLLNGLYWTTWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTPWVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSFNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLAGFAIMFFIIFIAFAQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPLYFVFYVFFVFFVLFNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLKKDKIIDIQNAVLAGDTNNDGKMDFDEWRVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSLDLEIQYEKSEILNKTRDVILPVVSLEEYRALNRRVDRMDNNTRVIVTKIDTVLEALESIEKDKARSRETMGIILNTLNS 726
[Close]
BLAST of PKD2-2 vs. Planmine SMEST
Match: SMESG000018504.1 (SMESG000018504.1)

HSP 1 Score: 535.028 bits (1377), Expect = 1.103e-177
Identity = 323/748 (43.18%), Postives = 468/748 (62.57%), Query Frame = 3 
Query:  291 SEHMDNEPTAMEDQHQIENVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDI-TDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTKQFNGEN---SDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEGIDEDERRNQIHNIINSELEKYN 2522
            ++  DN P AM+ ++  +N   T    +E  + +  CW KFK  +RSLWATK TE+  E++ LY  TTVREL++Y++FL +L II F M     FY+T  L  LFL  +F+D   +F+++   S+ W++L GP LNGLYW+ WYN +++  ++ + +Y+EN++LG+PRIRQ++V+NNSC IP + Q  +  CY+ +S   E K +FG  NS+AW YT    L S  +    + Y  GGFY DL+ ++  +L ++ SLF N W+   TR + +DFT+YN NINLF +++L+ EFP +GGV  S EFR VKL+RY++  D+F+ ACE++F L+++YYI+EE IEI KHK AYF   WN LD++V+ + ++C  F IYR   +Q ++  LL N N  P F++LS+ Q Q++N  A  LF+A  KIFKYISFNK MTQL STL    KDL GF++MFFI+F AFA+ GY IFGSQ+ ++        T FRIIL D ++++L   + I+GP+YFIL+ FFVFF+L NMFLAI+ D Y                 D+ +  +R V + L  K++KI D+++A+   D N+D  +D+DEW+ ELK RGYA+ EIES+F K+D DGDR L+  EQ  +  ELN +K  +E ++ E +  N E    SD  +  I   +Y  L R +D +E  I  +  K D +L NF  + K K    +    +L A +      ED R+ +I  II  EL K N
Sbjct:   15 ADSHDNAPCAMDGEY-FDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYMLFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVLYLLYYIIEELIEIDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFLAILDDAY-----------------DFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERD-NQEKLIESDAIQP-ISYAKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLN 742
[Close]
BLAST of PKD2-2 vs. Planmine SMEST
Match: SMESG000018504.1 (SMESG000018504.1)

HSP 1 Score: 535.028 bits (1377), Expect = 1.290e-177
Identity = 323/748 (43.18%), Postives = 468/748 (62.57%), Query Frame = 3 
Query:  291 SEHMDNEPTAMEDQHQIENVYKTQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVRELIIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVSTISNVWQYLFGPFLNGLYWDRWYNGQDI-TDDTDLVYYENQILGIPRIRQLKVRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLNSSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFIDFTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAACEVIFCLFXXXXXXXXXXXXRKHKLAYFYEFWNWLDIVVIIISLVCAIFDIYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIFKYISFNKTMTQLSSTLTRSSKDLXXXXXXXXXXXXXXXELGYFIFGSQIEDFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYXXXXXXXXXXXXXNMFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRDIQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTLNLNEQXXXXXXXXXXXXXXXXXXXXTKQFNGEN---SDYNKTNIDIDEYNILKRRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEGIDEDERRNQIHNIINSELEKYN 2522
            ++  DN P AM+ ++  +N   T    +E  + +  CW KFK  +RSLWATK TE+  E++ LY  TTVREL++Y++FL +L II F M     FY+T  L  LFL  +F+D   +F+++   S+ W++L GP LNGLYW+ WYN +++  ++ + +Y+EN++LG+PRIRQ++V+NNSC IP + Q  +  CY+ +S   E K +FG  NS+AW YT    L S  +    + Y  GGFY DL+ ++  +L ++ SLF N W+   TR + +DFT+YN NINLF +++L+ EFP +GGV  S EFR VKL+RY++  D+F+ ACE++F L+++YYI+EE IEI KHK AYF   WN LD++V+ + ++C  F IYR   +Q ++  LL N N  P F++LS+ Q Q++N  A  LF+A  KIFKYISFNK MTQL STL    KDL GF++MFFI+F AFA+ GY IFGSQ+ ++        T FRIIL D ++++L   + I+GP+YFIL+ FFVFF+L NMFLAI+ D Y                 D+ +  +R V + L  K++KI D+++A+   D N+D  +D+DEW+ ELK RGYA+ EIES+F K+D DGDR L+  EQ  +  ELN +K  +E ++ E +  N E    SD  +  I   +Y  L R +D +E  I  +  K D +L NF  + K K    +    +L A +      ED R+ +I  II  EL K N
Sbjct:   26 ADSHDNAPCAMDGEY-FDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYMLFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTVKLIRYVNPLDFFVLACEILFVLYLLYYIIEELIEIDKHKSAYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFLAILDDAY-----------------DFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERD-NQEKLIESDAIQP-ISYAKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLN 753
The following BLAST results are available for this feature:
BLAST of PKD2-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PKD21.614e-17942.88polycystin 2, transient receptor potential cation ... [more]
PKD2L11.617e-17442.68polycystin 2 like 1, transient receptor potential ... [more]
PKD2L21.002e-13746.20polycystin 2 like 2, transient receptor potential ... [more]
PKD2L21.097e-13746.20polycystin 2 like 2, transient receptor potential ... [more]
PKD2L23.354e-13045.03polycystin 2 like 2, transient receptor potential ... [more]
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BLAST of PKD2-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pkd-22.668e-10434.99Polycystin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9U... [more]
lov-15.221e-2320.35Location of vulva defective 1 [Source:UniProtKB/S... [more]
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BLAST of PKD2-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Pkd21.809e-5334.87gene:FBgn0041195 transcript:FBtr0080365[more]
brv34.011e-923.81gene:FBgn0040333 transcript:FBtr0340092[more]
brv34.542e-928.33gene:FBgn0040333 transcript:FBtr0300708[more]
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BLAST of PKD2-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pkd20.000e+040.24polycystic kidney disease 2 [Source:NCBI gene;Acc:... [more]
pkd2l10.000e+042.46polycystic kidney disease 2-like 1 [Source:ZFIN;Ac... [more]
pkd1l2a7.153e-4326.83polycystic kidney disease 1 like 2a [Source:ZFIN;A... [more]
pkd1l2a5.224e-4226.83polycystic kidney disease 1 like 2a [Source:ZFIN;A... [more]
pkd1l2b2.186e-4027.20polycystic kidney disease 1 like 2b [Source:ZFIN;A... [more]
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BLAST of PKD2-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
usp330.000e+040.95ubiquitin specific peptidase 33 [Source:Xenbase;Ac... [more]
usp330.000e+041.36ubiquitin specific peptidase 33 [Source:Xenbase;Ac... [more]
usp330.000e+041.04ubiquitin specific peptidase 33 [Source:Xenbase;Ac... [more]
usp330.000e+041.42ubiquitin specific peptidase 33 [Source:Xenbase;Ac... [more]
usp330.000e+041.79ubiquitin specific peptidase 33 [Source:Xenbase;Ac... [more]
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BLAST of PKD2-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pkd24.754e-18041.66polycystin 2, transient receptor potential cation ... [more]
Pkd2l11.152e-17242.88polycystic kidney disease 2-like 1 [Source:MGI Sym... [more]
Pkd2l27.062e-13445.33polycystic kidney disease 2-like 2 [Source:MGI Sym... [more]
Pkd2l27.062e-13445.33polycystic kidney disease 2-like 2 [Source:MGI Sym... [more]
Pkd1l24.034e-3524.11polycystic kidney disease 1 like 2 [Source:MGI Sym... [more]
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BLAST of PKD2-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q4GZT3|PKD2_BOVIN0.000e+043.28Polycystin-2 OS=Bos taurus OX=9913 GN=PKD2 PE=2 SV... [more]
sp|Q6IVV8|PKD2_DANRE0.000e+040.24Polycystin-2 OS=Danio rerio OX=7955 GN=pkd2 PE=1 S... [more]
sp|O35245|PKD2_MOUSE3.325e-17941.66Polycystin-2 OS=Mus musculus OX=10090 GN=Pkd2 PE=1... [more]
sp|H2LRU7|PKD2_ORYLA6.206e-17939.20Polycystin-2 OS=Oryzias latipes OX=8090 GN=pkd2 PE... [more]
sp|Q13563|PKD2_HUMAN7.749e-17942.88Polycystin-2 OS=Homo sapiens OX=9606 GN=PKD2 PE=1 ... [more]
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BLAST of PKD2-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0H3YKM70.000e+0100.00PKD2-2 OS=Schmidtea mediterranea OX=79327 GN=PKD2-... [more]
A0A267F8W20.000e+049.02Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8GRD30.000e+047.55Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8FWB20.000e+047.31Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267G2D40.000e+048.89Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of PKD2-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pkd20.000e+040.13polycystin 2, transient receptor potential cation ... [more]
pkd2l11.311e-17941.92polycystic kidney disease 2-like 1 protein [Source... [more]
pkd1l2a9.431e-4327.20polycystin 1 like 2 [Source:NCBI gene;Acc:10304417... [more]
ENSAMXT00000006495.22.679e-3824.46pep primary_assembly:Astyanax_mexicanus-2.0:5:3500... [more]
pkd1a5.504e-1323.69polycystic kidney disease 1a [Source:ZFIN;Acc:ZDB-... [more]
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BLAST of PKD2-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
pkd2l10.000e+048.92polycystic kidney disease 2-like 1 [Source:ZFIN;Ac... [more]
pkd2l11.447e-17845.93polycystic kidney disease 2-like 1 [Source:ZFIN;Ac... [more]
pkd22.639e-9229.50polycystic kidney disease 2 [Source:NCBI gene;Acc:... [more]
ENSPMAT00000007306.14.115e-1720.00pep scaffold:Pmarinus_7.0:GL480012:400827:419749:1... [more]
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BLAST of PKD2-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of PKD2-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO470230.000e+048.45Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO492003.161e-6031.90Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO448844.856e-5728.79Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO400511.248e-5527.89Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO447441.816e-5429.35Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of PKD2-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pkd22.530e-18039.28polycystin 2, transient receptor potential cation ... [more]
pkd23.652e-17939.87polycystin 2, transient receptor potential cation ... [more]
pkd2l14.393e-16639.63polycystin 2 like 1, transient receptor potential ... [more]
pkd2l15.628e-16439.63polycystin 2 like 1, transient receptor potential ... [more]
pkd22.328e-15435.73polycystin 2, transient receptor potential cation ... [more]
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BLAST of PKD2-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000033381.10.000e+096.46SMESG000033381.1[more]
SMESG000033381.10.000e+095.89SMESG000033381.1[more]
SMESG000018492.10.000e+049.86SMESG000018492.1[more]
SMESG000018504.11.103e-17743.18SMESG000018504.1[more]
SMESG000018504.11.290e-17743.18SMESG000018504.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30010684
GenBankAKN21728.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010684 ID=SMED30010684|Name=PKD2-2|organism=Schmidtea mediterranea sexual|type=transcript|length=2884bp
TAACAATACTTGGAAGAAACAACTATTTTAAAATTCGTGTCAGAAATACT
TCAGATTCTTCATTCAAAGAATTAGAAATTCAACCGAAATCTTTCAAAAT
ACCACCATCCGTTTGTATGGCTCAAGCAAAAATAAATGGCCTTCAATTGT
TACAATTCAAATCAGAAAAGACTATTACAACCTAGTGCACGTGGAGAATT
TTTCAAATGCATAATTACGGTATGAACAAAAGTAGACCCCCTACAGCTGA
TAGTAGACGCGTTTTATGGAATGATGAGGATTATGTAGAAAGTGAACACA
TGGATAATGAGCCAACTGCAATGGAAGATCAACACCAGATTGAAAATGTT
TACAAGACACAAGCCGTCACGGAAGAACAAAAATATTCTTCAAATGGTTG
CTGGTGGAAATTCAAAAGAATTTTAAGATCTCTTTGGGCAACAAAATTAA
CTGAGGACACTGGAGAGAACAGAGAATTATATATTAAAACAACTGTTAGA
GAACTGATTATTTATGTAGTATTTTTAACAATTTTAATGATAATTGCCTT
TGGAATGATTGATCAAGTCACTTTCTACTATACAAAAGCTTTGAAAACAC
TTTTCTTAGATGAAAAGTTTGATGACAAGGAAAAGTCATTTACAACGGTT
TCCACAATTTCCAATGTCTGGCAATACTTGTTTGGGCCATTTTTAAATGG
GCTTTACTGGGATAGATGGTACAATGGGCAAGACATCACGGATGACACGG
ATTTAGTTTATTATGAGAATCAAATATTGGGCATTCCGAGAATCCGACAA
CTCAAAGTACGCAACAATAGTTGCGAAATCCCCAAAGTTTTTCAGGGTGA
TATGAAACATTGCTATAGCGAATTCAGTTCGGAAAATGAAGACAAAAACA
ATTTTGGTTTGAATAATTCTACCGCATGGATTTACACATCACCTGAGAGT
TTAAATTCTTCTGGCTATTTCAGTTTATTTAGTGAATATCATGATGGGGG
ATTCTATCAAGATTTATCAAGAAATAAAACGATTACTTTACAAATGCTAA
GATCCTTATTCGAAAATAGCTGGGTTACATTGGGTACTCGGGTGATCTTC
ATTGACTTTACTTTGTACAATCCCAATATTAATCTATTTAGTGTAATGCG
ATTAATATTTGAATTTCCCACAATCGGTGGTGTAAAAACGTCAAACGAAT
TCCGAGTTGTAAAGTTGTTAAGATACATTTCAACCTTTGACTATTTCATT
GCTGCGTGTGAAGTCATATTCTGCCTGTTCATTGTCTATTATATTGTCGA
AGAAACTATTGAGATTAGGAAGCACAAATTGGCATATTTTTATGAATTCT
GGAACTGGTTAGATATTGTTGTAATTATTATAAGCCTAGTTTGCGCTATA
TTCGACATCTACCGAACGGCCAGTGTACAAAAACTTATTCAGGGACTTCT
ATCGAATGAAAACCAATTTCCAGCCTTTGACTTCCTAAGTTATTGTCAAC
AACAATTTAACAATGCGGTAGCGATAAATTTATTTATTGCTTGGATAAAG
ATATTCAAATACATCAGTTTCAATAAAACAATGACACAGCTTAGTTCGAC
TTTAACTCGAAGTTCTAAAGACTTATTCGGATTTGCTGTAATGTTTTTCA
TAATTTTCTTTGCTTTTGCTGAATTAGGATATTTTATTTTTGGATCACAA
ATTGAAGATTTTGAAAATCTTATTAAATCTGCACTAACTCAATTTCGAAT
TATCCTGGGAGACTTTGATTATCAACAGTTAGAGTCTGCTCATCGAATAA
TTGGGCCGGTTTATTTTATTTTATTTACATTTTTTGTTTTTTTTGTTTTA
ATCAACATGTTTCTCGCTATTATTACTGATACCTATGCTGAGGTAAAAGC
CGAAATAGCAACACAGAAAAATGAATTTGAAATGGCAGATTATTTTCGTA
ATACAGCTAGAAATGTTCTACAGTTGCTGCAATTCAAACAACAAAAGATT
CGAGACATTCAAGATGCAATTCTAAATGCTGATATAAATAGTGATAAGAA
ATTGGACTACGATGAATGGAGAAATGAACTGAAATCACGGGGCTATGCTG
ATGCTGAAATTGAGTCAGTTTTTGTCAAATATGACAAAGACGGAGATCGG
ACTTTGAATTTAAATGAACAGAAAAATCTAGAAGGGGAATTGAATATTGA
GAAGGAGCTAATAGAAAAAGATATAGAGGAAACAAAACAATTCAATGGCG
AAAATTCTGATTACAATAAAACAAATATAGACATTGACGAATACAATATT
TTAAAAAGGCGAGTAGACCGAATGGAAGAAAATATAAGTGATATTGTTTT
GAAGCTTGACAAACTTTTGCAAAACTTTTCCCAGTTGGATAAAATGAAAA
TTGACCAGTCTAAAGTCATTTCTTCGTTGCTAGAAGCTTTAAACAATACC
GAAGGAATTGATGAAGATGAAAGAAGAAATCAGATACATAATATAATAAA
TAGTGAATTGGAAAAATATAATTATTCCGACACAATCTCCATAGGTAATG
TAAGCAGTGCATCACGGCCTGGAACGGCTAGGAGCACAAGGAAAGACTAA
AGCACACTGAGGAAACAATAATACAGAACTAAATATCGGTGTAACTCCAT
ATAACTTCCATGTAATTGAGAAGCAAGAATTGTTGTACGGGATCTCAATA
GAAAAATGATGCGTGAGACAAACACCGTCTCAAGCGACCTGAATGTCTAC
AGTACATGAAAGACATGATATCCTTCCTTTTCATGGCCTTCAACTGTTTA
ATCAAATTGAACATCATCATCTCTATTTTAACATTTTTCCTTCTGAATGT
TTTCAAAAACTTAATAATAATATCGGAAGTGATT
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protein sequence of SMED30010684-orf-1

>SMED30010684-orf-1 ID=SMED30010684-orf-1|Name=SMED30010684-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=798bp
MHNYGMNKSRPPTADSRRVLWNDEDYVESEHMDNEPTAMEDQHQIENVYK
TQAVTEEQKYSSNGCWWKFKRILRSLWATKLTEDTGENRELYIKTTVREL
IIYVVFLTILMIIAFGMIDQVTFYYTKALKTLFLDEKFDDKEKSFTTVST
ISNVWQYLFGPFLNGLYWDRWYNGQDITDDTDLVYYENQILGIPRIRQLK
VRNNSCEIPKVFQGDMKHCYSEFSSENEDKNNFGLNNSTAWIYTSPESLN
SSGYFSLFSEYHDGGFYQDLSRNKTITLQMLRSLFENSWVTLGTRVIFID
FTLYNPNINLFSVMRLIFEFPTIGGVKTSNEFRVVKLLRYISTFDYFIAA
CEVIFCLFIVYYIVEETIEIRKHKLAYFYEFWNWLDIVVIIISLVCAIFD
IYRTASVQKLIQGLLSNENQFPAFDFLSYCQQQFNNAVAINLFIAWIKIF
KYISFNKTMTQLSSTLTRSSKDLFGFAVMFFIIFFAFAELGYFIFGSQIE
DFENLIKSALTQFRIILGDFDYQQLESAHRIIGPVYFILFTFFVFFVLIN
MFLAIITDTYAEVKAEIATQKNEFEMADYFRNTARNVLQLLQFKQQKIRD
IQDAILNADINSDKKLDYDEWRNELKSRGYADAEIESVFVKYDKDGDRTL
NLNEQKNLEGELNIEKELIEKDIEETKQFNGENSDYNKTNIDIDEYNILK
RRVDRMEENISDIVLKLDKLLQNFSQLDKMKIDQSKVISSLLEALNNTEG
IDEDERRNQIHNIINSELEKYNYSDTISIGNVSSASRPGTARSTRKD*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR003915PKD_2
IPR002048EF_hand_dom
IPR011992EF-hand-dom_pair
IPR027359Volt_channel_dom_sf
IPR013122PKD1_2_channel
IPR018247EF_Hand_1_Ca_BS
Vocabulary: molecular function
TermDefinition
GO:0005509calcium ion binding
GO:0005262calcium channel activity
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0050982detection of mechanical stimulus
GO:0070588calcium ion transmembrane transport