Prolyl 4-hydroxylase subunit alpha-1-like protein

Overview


Name	Prolyl 4-hydroxylase subunit alpha-1-like protein
Smed ID	SMED30010666
Length (bp)	1835

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Prolyl 4-hydroxylase subunit alpha-1-like protein (SMED30010666) t-SNE clustered cells

Violin plots show distribution of expression levels for Prolyl 4-hydroxylase subunit alpha-1-like protein (SMED30010666) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Prolyl 4-hydroxylase subunit alpha-1-like protein (SMED30010666) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30010666

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 11

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30010666	SMESG000005668.1	dd_Smed_v4_2877_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30010666	SMESG000005668.1	dd_Smed_v4_2877_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30010666	SMESG000005668.1	dd_Smed_v4_2877_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30010666	SMESG000005668.1	dd_Smed_v4_2877_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010666	SMESG000005668.1	Contig30825	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010666	SMESG000005668.1	Contig30825	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010666	SMESG000036778.1 SMESG000005668.1 SMESG000003594.1	Contig52497	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010666	SMESG000036778.1 SMESG000005668.1 SMESG000003594.1	Contig52497	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010666	SMESG000005668.1	Contig38990	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010666	SMESG000005668.1	Contig38990	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30010666	SMESG000005668.1	dd_Smed_v4_2877_0_1	dd_Smed_v4	PMID:30962434 Cote et al., 2019

Note: Hover over icons to view figure legend

Homology

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Human
Match: P4HA2 (prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8547])

HSP 1 Score: 356.681 bits (914), Expect = 1.043e-115
Identity = 212/544 (38.97%), Postives = 311/544 (57.17%), Query Frame = 2

Query:   68 RFFLFSILVAIF---NCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYY---LEKISEEIVPNNDENP-----GFSDHY-----DGNFYTALCRGESPIEVSEREKNLKCY----NKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPC 1636
            + ++ ++L+A F   +C+  E FT++  ++ +  AEK+L + L +Y+L EE +L+++  +A +++   +++   +D+   E Y ++P+N+Y   ++   DW    DLV       F   L  +   F    P  +D  GA  A++RLQ+TY LD   +  G++   +    L+ DDCF +G  AY + ++   V W ++ L      +   + T  +  +LDYLSY +  +G    AL  T  LL    S   +R   N  Y+   LE+  E+ + N  E       G  +       + + Y +LCRGE       R+K L C     N+ P     I P K E  +  P +V  +D++ DEEIE IK +A PKL RATVR+P TG+L  ASYR+SKS+WL  D D + +++N+R+   TGL ++ AE LQV NYG+GG Y PHFD  +   +D F+ +  GNR+AT L YMSDVEAGGATVF ++GA +WPKKG+A FW+NL  +GE D  TRHA CPVLVG KWV NKWFHERGQEF RPC
Sbjct:    2 KLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWANKMEA--LTSKSAADA---EGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQFF----PTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGE---EATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPS--HERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRAPQLL--IAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 529

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Query:   68 RFFLFSILVAIF---NCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYY---LEKISEEIVPNNDENP-----GFSDHY-----DGNFYTALCRGESPIEVSEREKNLKCY----NKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPC 1636
            + ++ ++L+A F   +C+  E FT++  ++ +  AEK+L + L +Y+L EE +L+++  +A +++   +++   +D+   E Y ++P+N+Y   ++   DW    DLV       F   L  +   F    P  +D  GA  A++RLQ+TY LD   +  G++   +    L+ DDCF +G  AY + ++   V W ++ L      +   + T  +  +LDYLSY +  +G    AL  T  LL    S   +R   N  Y+   LE+  E+ + N  E       G  +       + + Y +LCRGE       R+K L C     N+ P     I P K E  +  P +V  +D++ DEEIE IK +A PKL RATVR+P TG+L  ASYR+SKS+WL  D D + +++N+R+   TGL ++ AE LQV NYG+GG Y PHFD  +   +D F+ +  GNR+AT L YMSDVEAGGATVF ++GA +WPKKG+A FW+NL  +GE D  TRHA CPVLVG KWV NKWFHERGQEF RPC
Sbjct:    2 KLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWANKMEA--LTSKSAADA---EGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQFF----PTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGE---EATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPS--HERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRAPQLL--IAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 529

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Query:   68 RFFLFSILVAIF---NCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYY---LEKISEEIVPNNDENP-----GFSDHY-----DGNFYTALCRGESPIEVSEREKNLKCY----NKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPC 1636
            + ++ ++L+A F   +C+  E FT++  ++ +  AEK+L + L +Y+L EE +L+++  +A +++   +++   +D+   E Y ++P+N+Y   ++   DW    DLV       F   L  +   F    P  +D  GA  A++RLQ+TY LD   +  G++   +    L+ DDCF +G  AY + ++   V W ++ L      +   + T  +  +LDYLSY +  +G    AL  T  LL    S   +R   N  Y+   LE+  E+ + N  E       G  +       + + Y +LCRGE       R+K L C     N+ P     I P K E  +  P +V  +D++ DEEIE IK +A PKL RATVR+P TG+L  ASYR+SKS+WL  D D + +++N+R+   TGL ++ AE LQV NYG+GG Y PHFD  +   +D F+ +  GNR+AT L YMSDVEAGGATVF ++GA +WPKKG+A FW+NL  +GE D  TRHA CPVLVG KWV NKWFHERGQEF RPC
Sbjct:    2 KLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWANKMEA--LTSKSAADA---EGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQFF----PTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGE---EATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPS--HERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRAPQLL--IAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 529

[Close]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Human
Match: P4HA2 (prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8547])

HSP 1 Score: 355.525 bits (911), Expect = 2.970e-115
Identity = 213/543 (39.23%), Postives = 310/543 (57.09%), Query Frame = 2

Query:   68 RFFLFSILVAIF---NCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYY---LEKISEEIVPNNDENP-----GFSDHY-----DGNFYTALCRGESPIEVSEREKNLKCY----NKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPC 1636
            + ++ ++L+A F   +C+  E FT++  ++ +  AEK+L + L +Y+L EE +L+++  +A +++   +++   +D+   E Y ++P+N+Y   ++   DW    DLV       F   L  +   F    P  +D  GA  A++RLQ+TY LD   +  G++   +    L+ DDCF +G  AY + ++   V W ++ L      +   + T  +  +LDYLSY +  +G    AL  T  LL    S   +R   N  Y+   LE+  E+ + N  E       G  +       + + Y +LCRGE       R+K L C     N+ P     I P K E  +  P +V  +D++ DEEIE IK +A PKL RATVR+P TG+L  ASYR+SKS+WL  D D + +++N+R+   TGL ++ AE LQV NYG+GG Y PHFD   +RP D+     GNR+AT L YMSDVEAGGATVF ++GA +WPKKG+A FW+NL  +GE D  TRHA CPVLVG KWV NKWFHERGQEF RPC
Sbjct:    2 KLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWANKMEA--LTSKSAADA---EGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQFF----PTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGE---EATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPS--HERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRAPQLL--IAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGVGGQYEPHFDF-SRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 527

[Close]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Human
Match: P4HA2 (prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8547])

HSP 1 Score: 355.525 bits (911), Expect = 2.970e-115
Identity = 213/543 (39.23%), Postives = 310/543 (57.09%), Query Frame = 2

Query:   68 RFFLFSILVAIF---NCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYY---LEKISEEIVPNNDENP-----GFSDHY-----DGNFYTALCRGESPIEVSEREKNLKCY----NKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPC 1636
            + ++ ++L+A F   +C+  E FT++  ++ +  AEK+L + L +Y+L EE +L+++  +A +++   +++   +D+   E Y ++P+N+Y   ++   DW    DLV       F   L  +   F    P  +D  GA  A++RLQ+TY LD   +  G++   +    L+ DDCF +G  AY + ++   V W ++ L      +   + T  +  +LDYLSY +  +G    AL  T  LL    S   +R   N  Y+   LE+  E+ + N  E       G  +       + + Y +LCRGE       R+K L C     N+ P     I P K E  +  P +V  +D++ DEEIE IK +A PKL RATVR+P TG+L  ASYR+SKS+WL  D D + +++N+R+   TGL ++ AE LQV NYG+GG Y PHFD   +RP D+     GNR+AT L YMSDVEAGGATVF ++GA +WPKKG+A FW+NL  +GE D  TRHA CPVLVG KWV NKWFHERGQEF RPC
Sbjct:    2 KLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWANKMEA--LTSKSAADA---EGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQFF----PTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGE---EATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPS--HERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRAPQLL--IAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGVGGQYEPHFDF-SRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 527

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Celegans
Match: phy-2 (Prolyl 4-hydroxylase subunit alpha-2 [Source:UniProtKB/Swiss-Prot;Acc:Q20065])

HSP 1 Score: 372.474 bits (955), Expect = 3.535e-122
Identity = 224/531 (42.18%), Postives = 319/531 (60.08%), Query Frame = 2

Query:   86 ILVAIFNCL-YGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEID---KFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQ-SPNSDIRDRLLKNKNYYLEKI-SEEIVPNNDENPGFSDHYDG----NFYTALCRGESPIEVSEREKNLKCYNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLK 1645
            +LV +   L + +LFTA+ DL  +  AEKD++ ++ QY+  E  RL++L  +A E     +  N  ++S+  E + +NPIN+YL  ++   +WK    + N  +NNK    L+   D   + + + P  +D+ GA  A++RLQ+TY LDT DL  G I   + + KL+  D F +G  AY ++++   + W +  + L KI   +P  T+ E  IL+YL+Y L   G  R AL+ T  L + +PN     R   N  +Y + +  +++V +          YDG    + Y ALCRGE P    + +  L+CY K   PF K+ P+KVE+    P  V+  ++IHD EIE IK +ASPKL RATV+N  TG LE A+YRISKSAWL  DLD +  ++N+RI   T LN   +E+LQV NYG+GGHY PHFD  +K  ++AF+ +  GNRIAT+LFYMS  E GGATVF  +G  ++P K  A FW+NL+ +GE D  TRHA CPVL+G KWV NKW HE+GQEF RPC L+
Sbjct:    5 LLVCLLAGLAHADLFTAIADLQHMLGAEKDVTTIIDQYIEAERARLDDLRRYAHEY----VHRNAHAESVGPE-FVTNPINAYLLIKRLTTEWKK---VENIMLNNKASTFLKNITDNRVRSEVKFPGEEDLSGAATALLRLQDTYSLDTLDLSNGIIGGEKVSNKLSGHDTFEVGRSAYNQKDYYHCLMWMQ--VALVKIENENPP-TIEEWEILEYLAYSLYQQGNVRRALSLTKRLAKIAPN---HPRAKGNVKWYEDMLQGKDMVGDLPPIVNKRVEYDGIVERDAYEALCRGEIPPVEPKWKNKLRCYLKRDKPFLKLAPIKVEILRFDPLAVLFKNVIHDSEIEVIKELASPKLKRATVQNSKTGELEHATYRISKSAWLKGDLDPVIDRVNRRIEDFTNLNQATSEELQVANYGLGGHYDPHFDFARKEEKNAFKTLNTGNRIATVLFYMSQPERGGATVFNHLGTAVFPSKNDALFWYNLRRDGEGDLRTRHAACPVLLGVKWVSNKWIHEKGQEFTRPCGLE 521

[Close]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Celegans
Match: dpy-18 (Prolyl 4-hydroxylase subunit alpha-1 [Source:UniProtKB/Swiss-Prot;Acc:Q10576])

HSP 1 Score: 343.969 bits (881), Expect = 6.031e-111
Identity = 210/539 (38.96%), Postives = 298/539 (55.29%), Query Frame = 2

Query:   77 LFSILVAIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIE---KYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFS-------DHYDGN----FYTALCRGESPIEVSEREKNLKCYNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKN 1648
            L  +++A       +LFT++ D+  + + E+++ ++L +Y+ +EE+RL +L + ++E    N         + IE   K  +NPIN++L  ++ + DWK+    +N   N     +     D +  R P  DD+ GA   ++RLQ+TY LDTKDL  GKI   Q N   +A DCF I   AY + +F   V W +E+      ++V+P  T+    IL+YL++ L      + AL  T EL +   +  R +   N  +Y + + +E V  +D             D   GN     Y ALCR E P+   +  + L CY K   PF    P+KVE+    P  V+  D+I D+E+  I+ +A PKL RATV +  TG L  A+YRISKSAWL     ++   +NKRI   T L +E AE+LQ+ NYGIGGHY PHFDH KK    +FE +  GNRIAT+LFYMS    GG TVFTE  + + P K  A FW+NL   G+ +  TRHA CPVLVG KWV NKW HE+G EF+RPC LK+
Sbjct:    3 LALLVLATIGYAVADLFTSIADMQNLLETERNIPKILDKYIHDEEERLVQLKKLSEEYSKKN--------EISIENGLKDITNPINAFLLIKRKIFDWKEIESKMN--ANKAGNVVSSITDDSYGVRYPTADDLSGAAIGLLRLQDTYRLDTKDLADGKIYADQGNYTFSAKDCFEIARAAYNEHDFYHTVMWMEEAQRRLG-DEVEP--TVEVEDILEYLAFALYKQNNLKHALKLTEELYKMNPTHPRAK--GNVKWYEDLLEQEGVRRSDMRKNLPPIQNRRPDSVLGNTERTMYEALCRNEVPVSQKDISR-LYCYYKRDRPFLVYAPIKVEIKRFNPLAVLFKDVISDDEVAAIQELAKPKLARATVHDSVTGKLVTATYRISKSAWLKEWEGDVVETVNKRIGYMTNLEMETAEELQIANYGIGGHYDPHFDHAKKEESKSFESLGTGNRIATVLFYMSQPSHGGGTVFTEAKSTILPTKNDALFWYNLYKQGDGNPDTRHAACPVLVGIKWVSNKWIHEKGNEFRRPCGLKS 525

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Celegans
Match: phy-4 (Proline HYdroxylase [Source:UniProtKB/TrEMBL;Acc:B1V8J4])

HSP 1 Score: 107.071 bits (266), Expect = 1.507e-25
Identity = 68/230 (29.57%), Postives = 109/230 (47.39%), Query Frame = 2

Query:  965 SEREKNLKCYNKIPHPFYKIGPLKVEVAFSKPRLVXXX-XXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITAST-GLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKN 1648
            S R+  L CY    H   +    KVE+  S+P ++  H  +        ++   + +L +  +   +T   E +  R +   WL +      ++I + + A+   L++  AE  Q+++Y   G+Y+PH+D+            RGNRIAT+L  +   + GG TVF  +   + PK G    W N  + GES+  T HA CP+  G+K     W HE+ QEF  PC L N
Sbjct:   44 SSRDGRLVCYRLHKHLLIR----KVEILSSEPFILQYHNQVHRRLAKRAVQEAEALRLEQLKISGFTT-TPEKSQVRAANGTWLIHTGRPSFARIFEGLQANINSLDLSTAEPWQILSYNADGYYAPHYDYLNPATNVQLVEGRGNRIATVLVILQIAKKGGTTVFPRLNLNIRPKAGDVIVWLNTLSTGESNSQTLHAACPIHEGTKIGATLWVHEKKQEFSLPCALTN 268

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Celegans
Match: Y43F8B.19 (pep chromosome:WBcel235:V:19510780:19512164:-1 gene:WBGene00077688.1 transcript:Y43F8B.19.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y43F8B.19)

HSP 1 Score: 94.3597 bits (233), Expect = 1.458e-21
Identity = 47/118 (39.83%), Postives = 65/118 (55.08%), Query Frame = 2

Query: 1274 LNIEMAEDLQVVNYGIGGHYSPHFDH---GKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQ 1618
            LN + AED+  ++Y  GGHY+ H D+     ++  D +    GNR  TL+      E+GGATVF  +GA +  K G A FWFN   N E +D++ HAGCP+  G K +   W   R Q
Sbjct:  104 LNFKTAEDILALSYNPGGHYAAHHDYLLYPSEKEWDEWMRVNGNRFGTLIMAFGAAESGGATVFPRLGAAVRTKPGDAFFWFNAMGNSEQEDLSEHAGCPIYKGQKQISTIWLRMRDQ 221

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Celegans
Match: phy-3 (Proline HYdroxylase [Source:UniProtKB/TrEMBL;Acc:Q9XUP0])

HSP 1 Score: 93.9745 bits (232), Expect = 8.320e-21
Identity = 48/133 (36.09%), Postives = 72/133 (54.14%), Query Frame = 2

Query: 1229 EITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEI---ERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQ 1618
            EI  +  KRI    GLN+ +AE    ++Y  GGHY+ H+D+   R +  ++    + GNRI TL+F +   E GG TVF  +G+ +    G A FWFN +A+ E + ++ H GCP+  G K +   W     Q
Sbjct:  152 EIKMQAQKRIP---GLNLTVAEHFSALSYLPGGHYAVHYDYLDYRSKQDYDWWMNKTGNRIGTLIFVLKPAEKGGGTVFPSIGSTVRANAGDAFFWFNAQADEEKEMLSNHGGCPIYEGRKVIATIWIRAYNQ 281

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Fly
Match: PH4alphaEFB (gene:FBgn0039776 transcript:FBtr0085650)

HSP 1 Score: 375.555 bits (963), Expect = 3.738e-123
Identity = 218/543 (40.15%), Postives = 319/543 (58.75%), Query Frame = 2

Query:  116 GELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKD-----KLDLVNDFVNN--KFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQS-PNSDIRDRLLKNKNYYLEKISEEI-------------VPNND-----ENPGFSDHYDGNFYTALCRGE---SPIEVSEREKNLKC---YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLK 1645
            GE++TAL ++ ++ + E  L   L  Y+  +E +LN L     E +  +  A     S +I  Y SNPIN+YL  ++   DW+      + D+  DF+ N  ++R +L         + P+ +D++GA  A++RLQ+TY LDT  +  GK+   Q + ++++DDCF +G  +Y   ++   V W  E++        +   +  +  IL+YL++     G   +AL  TNELLQ  P+    +R   NK +Y ++I++++             +P +D      +P   D  +   Y  LCRGE   SP ++    ++L+C    N++P  F ++GPLK+E   + P +VI HD ++D EI+ IK +A P+  RATV+N  TG LE A+YRISKSAWL    D +   + +R    TGL+++ AE+LQVVNYGIGGHY PHFD  +K  Q AFE +  GNRIAT+LFYMSDVE GGATVFT +   L+PKKG+AAFW NL  +G+ D  TRHA CPVL G+KWV NKW HERGQEF+RPC L+
Sbjct:   23 GEVYTALAEMEELLETESVLITNLEGYIRVQEDKLNFLKNKMDEYQREHSDA-----SHDITAYVSNPINAYLLTKRLTTDWRQVENLMEHDVGTDFLQNITQYRSLL---------KFPSDEDLNGAAVALLRLQDTYQLDTSSVARGKLNGIQYSTEMSSDDCFELGRQSYVNHDYYHTVLWMNEAMARMLEEPTNHTQSFTKADILEYLAFSTYKEGNIESALTMTNELLQLLPH---HERANGNKRFYEKEIAQQLQLRKMKGDDGTDEMPKSDLPVAKSDPAIFDMTERRAYEMLCRGELKPSPSDL----RSLRCRYVTNRVP--FLRLGPLKLEEVHADPYIVIYHDAMYDSEIDLIKRMARPRFRRATVQNSVTGALETANYRISKSAWLKTQEDRVIETVVQRTADMTGLDMDSAEELQVVNYGIGGHYEPHFDFARKEEQRAFEGLNLGNRIATVLFYMSDVEQGGATVFTSLHTALFPKKGTAAFWMNLHRDGQGDVRTRHAACPVLTGTKWVSNKWIHERGQEFRRPCDLE 542

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Fly
Match: PH4alphaPV (gene:FBgn0051015 transcript:FBtr0085670)

HSP 1 Score: 263.077 bits (671), Expect = 3.327e-80
Identity = 169/512 (33.01%), Postives = 262/512 (51.17%), Query Frame = 2

Query:  128 TALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQ-EEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFSDHYDG--NFYTALCRGESPIEVSEREKNLKC-YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 1651
            T++  + K+   E  L + L  Y +  EK+L  +      L+  N  A   +     E+Y SNP+NS+   R+   DW      ++D V      I Q E I + ++ +P   D++ A+ A+ R+Q TY L   ++  G +   Q NV L   D + +G   + ++N+  A  W  +S+ L +   +     +++  +    +  L  +  +  AL   N  L     DI+  L K++      I   I    +  P       G    Y   CRG+ P      +  L C YN+   PF  + PLK+E+    P +V+ HD++  +EI+ ++ +A+P L RATV   S+G  E    R SK AW P+  + +T ++N RI+  TG N+  +E LQ++NYG+GGHY  H+D   K   +   +  G+RIAT+LFY++DVE GGATVF  +   ++P++GS   W+NLK NG+ D  T HA CPV+VGSKWV NKW  ER Q F RPC  K +
Sbjct:   34 TSVAGMVKLLDLEAQLIDNLEDYAVELEKKLQTVRRSITSLRLENDKARSST-----EEYLSNPLNSFSLIRRMNRDWIIWQLYMDDPVG-----ISQVERIQELREHMPTHTDVEEAVTALDRIQSTYGLKVPEISHGFLNGKQYNVSLTVLDTYAMGQILFDQKNYLAAASWIYQSVVLMEAFSMAAPLEISKNEVRMVYAETLLKLNQHADALKVVNIALTDNPHDIKLLLKKSE------IETMIRTGTNNAPPVKVQATGVPTAYQIGCRGQFP---PSADSKLYCLYNRTTSPFLILAPLKMELVGLDPYMVLYHDVLSPKEIKELQGMATPGLKRATVYQASSGRNEVVKTRTSKVAWFPDGYNPLTVRLNARISDMTGFNLYGSEMLQLMNYGLGGHYDQHYDFFNKTNSNMTAMS-GDRIATVLFYLTDVEQGGATVFPNIRKAVFPQRGSVVMWYNLKDNGQIDTQTLHAACPVIVGSKWVCNKWIREREQIFSRPCLKKRM 525

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Fly
Match: PH4alphaSG1 (gene:FBgn0051014 transcript:FBtr0085686)

HSP 1 Score: 256.914 bits (655), Expect = 1.064e-77
Identity = 179/548 (32.66%), Postives = 289/548 (52.74%), Query Frame = 2

Query:   71 FFLFSILVAIFNCLY---GELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWK-DKLDLVNDFVN-NKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSN---VKLNADDCFNIGVHAYKKENFPIAVKWFKES---LNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELL-QSPNSDIRDRLLKNKNYYLEKISEE--IVPNND-ENPGFSDHYDGN---FYTALCRGESPIEVSERE-KNLKCYNKIPH---PFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKN 1648
             F  SI++++  C++   G+ ++A+ +L ++   E  + E   +Y+   ++    L  F  ++       ND  D   +E+YF NPIN+++  ++ VHDWK +  D V D  N   ++  L + ++K   + P  +D+ GA  A++RLQ  Y L+T  L  G +   + N     L+A DCF +G +  + + +    +W  E+   L+   +  + P+  +++  IL++LS     +G  + A    NE+L + P+    +  LKNK  Y  +++ E    P    E P  ++         YT +CRGE  +  S RE +NL+C+  + H   P+Y++ P K+E     P +  +H+++ D EI+ I       + R+ V          +  RIS++ WL  D +   SKI +R+   TGL+ E AE LQ+VNYGIGG Y PHFD  +   Q  F   +GNR+ T LFY++DV  GGAT F  +   + P KGS   W+NL ++   D  T+HAGCPVL GSKW+ N+WFH   QEF+RPC L +
Sbjct:    1 MFRLSIILSLL-CVFPVNGDYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQIDE---QQNDRGD---LEEYFGNPINAFITIKRLVHDWKFNVFDPVFDSSNFETYKNNLSDSLEKINFKGPTQEDLHGATRALLRLQNMYQLNTDHLASGVLHPGEKNALGTSLSASDCFELGKNLCEIKEYSYGSEWLLEARKRLHGKPLGFISPN--VSDVEILEHLSSAFNGLGNLKLAYKLNNEILDKKPD---HEEALKNKILYEGQLARERSFAPRKQVELPQIAEKEQKESYKLYTQVCRGE--LHQSPREQRNLRCW--LYHQGVPYYRLSPFKIEQLNVDPYVAYVHEVLWDSEIDTIMEHGKGNMERSKVGQSENSTT--SEVRISRNTWLWYDANPWLSKIKQRLEDVTGLSTESAEPLQLVNYGIGGQYEPHFDFVEDDGQSVFSW-KGNRLLTALFYLNDVALGGATAFPFLRLAVPPVKGSLLIWYNLHSSTHKDFRTKHAGCPVLQGSKWICNEWFHVGAQEFRRPCGLSS 529

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Fly
Match: PH4alphaMP (gene:FBgn0026190 transcript:FBtr0085689)

HSP 1 Score: 243.817 bits (621), Expect = 1.026e-72
Identity = 165/552 (29.89%), Postives = 281/552 (50.91%), Query Frame = 2

Query:   56 MDFKRFFLFSILVAIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTY--NISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRL--PNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCL---GSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPNNDEN---------PG-FSDHYDGNFYTALCRGE-SPIEVSEREKNLKCYNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRN-PSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIE---RGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLK 1645
            M   +  LF +L  + +C +GE F++   L+K+F+ E  L   L  YV       NE+ + A+ L++    I     + +  I+ Y +NP+N++   ++   DW+           +  R    + +   ++ L  P+ DD  G+  A+ RLQ+TY LD  +L  G +   +    ++  DCF +G H Y   ++   V W ++S+ L            +E + LD++   +     +G + +AL+  N +L S   D R  LL+ +        EE++ + D+N         PG + +  +   Y  +CRGE +P+    +++NL+C  ++        P K+E     P +V +H +I  ++ + ++  A P++ R+TV +    G    A++R S+ A      +  T  +++ +   +GLN++ AEDLQV NYGIGGHY PH+D     P++    E    GNR+AT ++Y++DVEAGG T F  +   + P++GS  FW+NL  +G+ D  T+HA CPVL GSKW+ N W  ER Q+  RPC L+
Sbjct:    1 MLLAKCVLFLVL-QVLSC-HGEFFSSTSGLAKLFETEVVLLAELQNYV-------NEINQHAEALQSEIDAIRVEHLNAADGIDDYLNNPVNAFRLIKRLHSDWET---FEGSVTADSSRSNYLDTMASLKENLSFPSQDDFVGSAIALTRLQQTYQLDVAELASGILNGVKYGTAMSWQDCFVLGQHLYALRDYNHTVPWLQQSMQLLGEQSYG-----SESASLDFMEAVVEYHREMGAHESALSLVNHVL-SIEPDQRSHLLEARQQL-----EELITDGDKNGLLHLTARRPGDYHESREFRMYEQVCRGELAPL--PSKQRNLRC--RLRKSRLGYAPFKLEELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTVYSLGGNGGSTAAAFRTSQGASFNYSRNAATKLLSRHVGDFSGLNMDYAEDLQVANYGIGGHYEPHWD---SFPENHIYQEGDLHGNRMATGIYYLADVEAGGGTAFPFLPLLVTPERGSLLFWYNLHPSGDQDFRTKHAACPVLQGSKWIANVWIRERNQDNVRPCDLE 522

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Fly
Match: CG9698 (gene:FBgn0039784 transcript:FBtr0085657)

HSP 1 Score: 239.58 bits (610), Expect = 5.390e-71
Identity = 172/545 (31.56%), Postives = 286/545 (52.48%), Query Frame = 2

Query:   71 FFLFSILVAIFN----CLYG-ELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDR--LPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFSDHYD--------GNF--YTALCRGESPIEVSEREKNLKC-YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEI---ERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKL 1642
            F +FS+L  +F+     + G E F+++ +++KVF  E+ +   + +++ + + +L+ L    +E +     A ++  S     YF +PIN YL  ++   DW+   +L+      K    L+    KF++R  +P+  +++GAID ++RLQ  Y L  KDL  G +       +LN++ C +I   A + ++  +A  W  E+ +  ++   + +  L  + IL  L      +  +R   +   EL+   ++   +   KN   +L  +SE+ + N  E+    +H          G F  Y+  C G   +   E +++L+C Y    HPF  I PLK E  F  P LV+ HD+I+  EI+ I+ +   +L RAT+ + +  ++  ++ R S+  ++P    ++ S I++R+   T LN++ AED Q  NYGIGGHY  H D   +   DA  +   E GNRIAT+LFY+SDV  GG T F ++   L PKK +AAFW NL A+G  D  T+H  CP++ GSKWV N+W  E  Q  +RPC+L
Sbjct:    3 FPVFSVLFLLFHQAIPSVSGVEFFSSIHEMTKVFGYEQKMVLHMQKFLSDNQDKLDFLKARLREFENERNEAREWGPS-----YFESPINKYLLNKRLTVDWQRVENLMATSTGEKPLTRLR----KFRNRETMPDKKELEGAIDGLLRLQYVYRLKAKDLARGILDGVDYGTQLNSEHCVDIARLALRDQHPRLAHSWLIEAND--RLTGGEKEEQLKPQ-ILALLVQAKKELEDFRGLNDTYQELIGIQSAS--EEHAKNYETFLNALSEKALLN--ESKPILEHAPIPEEGEPVGEFQAYSLTCSGHWRLTPKE-QRHLRCGYVTETHPFLWIAPLKAEELFQDPLLVLYHDVIYQSEIDVIRKLTENRLMRATITSHNESVV--SNVRTSQFTFIPVTAHKVLSTIDQRVADMTNLNMKYAEDHQFANYGIGGHYGQHMDWFYQTTFDAGLVSSPEMGNRIATVLFYLSDVAQGGGTAFPQLRTLLKPKKYAAAFWHNLHASGVGDVRTQHGACPIIAGSKWVQNRWIRENDQSDRRPCEL 528

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Zebrafish
Match: p4ha1a (prolyl 4-hydroxylase, alpha polypeptide I a [Source:ZFIN;Acc:ZDB-GENE-040724-91])

HSP 1 Score: 357.836 bits (917), Expect = 3.548e-116
Identity = 212/531 (39.92%), Postives = 303/531 (57.06%), Query Frame = 2

Query:  113 YGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNV----KLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYY-----LEKISEEIVPNNDENPGFSDHYDG--------NFYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLK 1645
            + + FT++  ++ +   EKDL   L  Y+  EE +L ++ ++A++L     +A       + E +  +P+N++   ++   +W +  DLV   +++ F   L  +   F    PN +D +GA  A++RLQ+TY LDT+ +  G +    + +     L  +DCF +G  AY   ++     W  ++L      +   + ++   + LDYLSY +   G    AL YT  LL         R L N  Y+      +K +E+     +E+    +  DG          Y  LCRGE       R+K+L C  +N   HPFY IGP+K E  + +PR++  H++I ++EIE IK ++ P+L RAT+ NP TG+LE A YRISKSAWL      +  +IN+RI   TGLN++ AE+LQV NYG+GG Y PHFD G+K   DAF E+  GNRIAT LFYMSDV AGGATVF EVGA + P KG+A FW+NL  +GE D  TRHA CPVLVG+KWV NKW HERGQEF+RPC LK
Sbjct:   22 HSDFFTSIGHMTDLLFTEKDLVTSLKDYIKAEESKLEQVKQWAEKLDALTATA-----VQDPEGFLGHPVNAFKLMKRLNTEWGEVEDLVLKDMSDGFISNLTIQRQYF----PNDEDQNGAAKALLRLQDTYKLDTQTISSGDLPGVNTGLPYKSTLTVEDCFELGKIAYSDADYYHTELWMAQALKQLDEGE---ESSVEIATALDYLSYSVYQQGELERALEYTKRLLTVEPE--HQRALGNLKYFDYQLAKQKKAEKEQSTKEESKKEQETSDGKKEYLPEKRKYEKLCRGEGLKMTPRRQKHLFCRYFNGNRHPFYTIGPVKQEDEWDRPRIIRYHEIITEQEIEKIKELSKPRLRRATISNPITGVLETAHYRISKSAWLAAYEHPVVDRINQRIEDITGLNVKTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVAAGGATVFPEVGAAVKPLKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCGLK 538

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Query:  113 YGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNV----KLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYY-----LEKISEEIVPNNDENPGFSDHYDG--------NFYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLK 1645
            + + FT++  ++ +   EKDL   L  Y+  EE +L ++ ++A++L     +A       + E +  +P+N++   ++   +W +  DLV   +++ F   L  +   F    PN +D +GA  A++RLQ+TY LDT+ +  G +    + +     L  +DCF +G  AY   ++     W  ++L      +   + ++   + LDYLSY +   G    AL YT  LL         R L N  Y+      +K +E+     +E+    +  DG          Y  LCRGE       R+K+L C  +N   HPFY IGP+K E  + +PR++  H++I ++EIE IK ++ P+L RAT+ NP TG+LE A YRISKSAWL      +  +IN+RI   TGLN++ AE+LQV NYG+GG Y PHFD G+K   DAF E+  GNRIAT LFYMSDV AGGATVF EVGA + P KG+A FW+NL  +GE D  TRHA CPVLVG+KWV NKW HERGQEF+RPC LK
Sbjct:   22 HSDFFTSIGHMTDLLFTEKDLVTSLKDYIKAEESKLEQVKQWAEKLDALTATA-----VQDPEGFLGHPVNAFKLMKRLNTEWGEVEDLVLKDMSDGFISNLTIQRQYF----PNDEDQNGAAKALLRLQDTYKLDTQTISSGDLPGVNTGLPYKSTLTVEDCFELGKIAYSDADYYHTELWMAQALKQLDEGE---ESSVEIATALDYLSYSVYQQGELERALEYTKRLLTVEPE--HQRALGNLKYFDYQLAKQKKAEKEQSTKEESKKEQETSDGKKEYLPEKRKYEKLCRGEGLKMTPRRQKHLFCRYFNGNRHPFYTIGPVKQEDEWDRPRIIRYHEIITEQEIEKIKELSKPRLRRATISNPITGVLETAHYRISKSAWLAAYEHPVVDRINQRIEDITGLNVKTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVAAGGATVFPEVGAAVKPLKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCGLK 538

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Zebrafish
Match: p4ha1a (prolyl 4-hydroxylase, alpha polypeptide I a [Source:ZFIN;Acc:ZDB-GENE-040724-91])

HSP 1 Score: 353.214 bits (905), Expect = 1.671e-114
Identity = 210/531 (39.55%), Postives = 301/531 (56.69%), Query Frame = 2

Query:  113 YGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNV----KLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYY-----LEKISEEIVPNNDENPGFSDHYDG--------NFYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLK 1645
            + + FT++  ++ +   EKDL   L  Y+  EE +L ++ ++A++L     +A       + E +  +P+N++   ++   +W +  DLV   +++ F   L  +   F    PN +D +GA  A++RLQ+TY LDT+ +  G +    + +     L  +DCF +G  AY   ++     W  ++L      +   + ++   + LDYLSY +   G    AL YT  LL         R L N  Y+      +K +E+     +E+    +  DG          Y  LCRGE       R+K+L C  +N   HPFY IGP+K E  + +PR++  H++I ++EIE IK ++ P+L RATV +P TG L  A YR+SKSAWL      +  +IN+RI   TGLN++ AE+LQV NYG+GG Y PHFD G+K   DAF E+  GNRIAT LFYMSDV AGGATVF EVGA + P KG+A FW+NL  +GE D  TRHA CPVLVG+KWV NKW HERGQEF+RPC LK
Sbjct:   22 HSDFFTSIGHMTDLLFTEKDLVTSLKDYIKAEESKLEQVKQWAEKLDALTATA-----VQDPEGFLGHPVNAFKLMKRLNTEWGEVEDLVLKDMSDGFISNLTIQRQYF----PNDEDQNGAAKALLRLQDTYKLDTQTISSGDLPGVNTGLPYKSTLTVEDCFELGKIAYSDADYYHTELWMAQALKQLDEGE---ESSVEIATALDYLSYSVYQQGELERALEYTKRLLTVEPE--HQRALGNLKYFDYQLAKQKKAEKEQSTKEESKKEQETSDGKKEYLPEKRKYEKLCRGEGLKMTPRRQKHLFCRYFNGNRHPFYTIGPVKQEDEWDRPRIIRYHEIITEQEIEKIKELSKPRLRRATVHDPQTGKLTTAQYRVSKSAWLAAYEHPVVDRINQRIEDITGLNVKTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVAAGGATVFPEVGAAVKPLKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCGLK 538

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Zebrafish
Match: p4ha1a (prolyl 4-hydroxylase, alpha polypeptide I a [Source:ZFIN;Acc:ZDB-GENE-040724-91])

HSP 1 Score: 353.214 bits (905), Expect = 1.671e-114
Identity = 210/531 (39.55%), Postives = 301/531 (56.69%), Query Frame = 2

Query:  113 YGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNV----KLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYY-----LEKISEEIVPNNDENPGFSDHYDG--------NFYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLK 1645
            + + FT++  ++ +   EKDL   L  Y+  EE +L ++ ++A++L     +A       + E +  +P+N++   ++   +W +  DLV   +++ F   L  +   F    PN +D +GA  A++RLQ+TY LDT+ +  G +    + +     L  +DCF +G  AY   ++     W  ++L      +   + ++   + LDYLSY +   G    AL YT  LL         R L N  Y+      +K +E+     +E+    +  DG          Y  LCRGE       R+K+L C  +N   HPFY IGP+K E  + +PR++  H++I ++EIE IK ++ P+L RATV +P TG L  A YR+SKSAWL      +  +IN+RI   TGLN++ AE+LQV NYG+GG Y PHFD G+K   DAF E+  GNRIAT LFYMSDV AGGATVF EVGA + P KG+A FW+NL  +GE D  TRHA CPVLVG+KWV NKW HERGQEF+RPC LK
Sbjct:   22 HSDFFTSIGHMTDLLFTEKDLVTSLKDYIKAEESKLEQVKQWAEKLDALTATA-----VQDPEGFLGHPVNAFKLMKRLNTEWGEVEDLVLKDMSDGFISNLTIQRQYF----PNDEDQNGAAKALLRLQDTYKLDTQTISSGDLPGVNTGLPYKSTLTVEDCFELGKIAYSDADYYHTELWMAQALKQLDEGE---ESSVEIATALDYLSYSVYQQGELERALEYTKRLLTVEPE--HQRALGNLKYFDYQLAKQKKAEKEQSTKEESKKEQETSDGKKEYLPEKRKYEKLCRGEGLKMTPRRQKHLFCRYFNGNRHPFYTIGPVKQEDEWDRPRIIRYHEIITEQEIEKIKELSKPRLRRATVHDPQTGKLTTAQYRVSKSAWLAAYEHPVVDRINQRIEDITGLNVKTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVAAGGATVFPEVGAAVKPLKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCGLK 538

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Zebrafish
Match: p4ha1b (prolyl 4-hydroxylase, alpha polypeptide I b [Source:ZFIN;Acc:ZDB-GENE-030131-4089])

HSP 1 Score: 351.673 bits (901), Expect = 5.939e-114
Identity = 207/530 (39.06%), Postives = 294/530 (55.47%), Query Frame = 2

Query:  113 YGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQ-SPNSDIRDRLLKNKNYYLEKISE-EIVPNNDENPGFSDHYDGNF------------YTALCRGESPIEVSEREKNLKCY--NKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 1651
            + + FT+   ++ +  AEKDL   L +Y+  EE RL ++ E+A +L +  I+A     + + E +  +P+N++   ++   +W D  +LV     N F   L  +   F    P  +D  GA  A++RLQ+TY L    +  G +       ++  +DC+ +G  AY   ++     W  ++L+     +  P   +++ +++DYLSY +   G    AL  T  +L+  PN    +  LK   + LEK  + E     ++     D  D               Y  LCRGE       R+  L C   N   +P   + P+K E  + +PR+V  H++I D EIE +K +A P+L RAT+ NP TG+LE A YRISKSAWL         +IN+RI   TGL ++ AE+LQV NYG+GG Y PHFD G+K   DAF E+  GNRIAT LFYMSDV AGGATVFT+VGA +WPKKG+A FW+NL  +GE D  TRHA CPVLVG+KWV NKW HERGQEF+RPC L  +
Sbjct:   18 HNDFFTSTGQMTDLLYAEKDLVTSLKEYIKQEENRLEQVKEWADKLDSLTITA-----TQDPEGFLGHPVNAFKLMKRLNSEWSDLENLVLKDTTNGFISNLTVQRQYF----PTDEDQTGAAKALLRLQDTYQLSANAISSGDLPGVVHKSRMTVEDCYELGKIAYSDADYYHTELWMAQALSQLDEGEESP---IDKVTVMDYLSYAIYQQGELDRALELTKRMLKLDPNHHRANGNLKYFEFQLEKQRKAENEKKEEDQKRVLDKRDAQRKRSKDPLPERKKYERLCRGEGIKLTPRRQSRLFCRYSNNNRNPRLLLAPVKQEDEWDRPRIVRYHEIISDSEIETVKEMAKPRLRRATISNPITGVLETAPYRISKSAWLSGYEHSTIERINQRIEDVTGLEMDTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFTDVGAAVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCALSEV 535

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Xenopus
Match: notch3 (notch 3 [Source:Xenbase;Acc:XB-GENE-6450008])

HSP 1 Score: 362.844 bits (930), Expect = 2.513e-118
Identity = 207/531 (38.98%), Postives = 307/531 (57.82%), Query Frame = 2

Query:   68 RFFLFSILVAIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFSDHYDGNFYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 1651
            +  L   L+ +F+C + + FT++  ++ +   EKDL   L  Y+  EE++L ++ ++A +L     +A     + + E Y  +P+N++   ++   +W    +L+   +++ F   L  +   F    PN +D  GA  A++RLQ+TY+LDT  +  G +   +    L A+DCF++G  AY   ++     W +++L+     +   + +L++  +LDYLSY +   G    AL  T   L+  N ++R  ++  ++        E            DH +   Y  LCRGE     S R+K L C  ++    P   + P K E  + KPR+V  HD+I DEEI  +K +A P+L RAT+ NP TG+LE A YRI+KSAWL    D + +++N+RI   TGL++  AE+LQV NYGIGG Y PHFD  +K   DAF+ +  GNR+AT LFYMSDVEAGGATVF EVGA ++PKKG+A FW+NL  +GE D  TRHA CPVLVG+KWV NKW HERGQEF+RPC L  +
Sbjct:    3 KIHLVLPLLGLFSCAHADFFTSIGHMTDLLNTEKDLVTSLKDYIKAEEQKLAQIKKWADKLDHLTDTA-----TKDPEGYLGHPVNAFKLMKRLNTEWVKLENLILKDISDGFISNLTIQRQYF----PNDEDQTGAAKALLRLQDTYNLDTDTISKGNLPGVKHKTSLTAEDCFDLGKTAYTDADYYHTELWMEQALSQLDAGE---ESSLDKVMVLDYLSYAVYQQGDLDKALTLTKRSLEG-NGNLR-HIMSKESNKSSSSPSEGAELRTRKGRPKDHLEKEKYEKLCRGEGVKMTSRRQKRLFCRYFDGKKDPLLILSPTKQEDEWDKPRIVRYHDIISDEEISKVKELAKPRLRRATISNPITGVLETAQYRITKSAWLSGYEDPVVARLNRRIEGVTGLDMSTAEELQVANYGIGGQYEPHFDFLRKYEPDAFKKLGTGNRVATWLFYMSDVEAGGATVFPEVGAAVYPKKGTAVFWYNLLESGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCNLSEL 519

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Xenopus
Match: notch3 (notch 3 [Source:Xenbase;Acc:XB-GENE-6450008])

HSP 1 Score: 359.762 bits (922), Expect = 9.359e-117
Identity = 206/530 (38.87%), Postives = 308/530 (58.11%), Query Frame = 2

Query:   68 RFFLFSILVAIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFSDHYDGNFYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKN 1648
            +  L   L+ +F+C + + FT++  ++ +   EKDL   L  Y+  EE++L ++ ++A +L     +A     + + E Y  +P+N++   ++   +W    +L+   +++ F   L  +   F    PN +D  GA  A++RLQ+TY+LDT  +  G +   +    L A+DCF++G  AY   ++     W +++L+     +   + +L++  +LDYLSY +   G    AL  T   L+  N ++R  ++  ++        E            DH +   Y  LCRGE     S R+K L C  ++    P   + P K E  + KPR+V  HD+I DEEI  +K +A P+L RAT+ NP TG+LE A YRI+KSAWL    D + +++N+RI   TGL++  AE+LQV NYGIGG Y PHFD  +K   DAF+ +  GNR+AT LFYMSDVEAGGATVF EVGA ++PKKG+A FW+NL  +GE D  TRHA CPVLVG+KWV NKW HERGQEF+RP K+++
Sbjct:    3 KIHLVLPLLGLFSCAHADFFTSIGHMTDLLNTEKDLVTSLKDYIKAEEQKLAQIKKWADKLDHLTDTA-----TKDPEGYLGHPVNAFKLMKRLNTEWVKLENLILKDISDGFISNLTIQRQYF----PNDEDQTGAAKALLRLQDTYNLDTDTISKGNLPGVKHKTSLTAEDCFDLGKTAYTDADYYHTELWMEQALSQLDAGE---ESSLDKVMVLDYLSYAVYQQGDLDKALTLTKRSLEG-NGNLR-HIMSKESNKSSSSPSEGAELRTRKGRPKDHLEKEKYEKLCRGEGVKMTSRRQKRLFCRYFDGKKDPLLILSPTKQEDEWDKPRIVRYHDIISDEEISKVKELAKPRLRRATISNPITGVLETAQYRITKSAWLSGYEDPVVARLNRRIEGVTGLDMSTAEELQVANYGIGGQYEPHFDFLRKYEPDAFKKLGTGNRVATWLFYMSDVEAGGATVFPEVGAAVYPKKGTAVFWYNLLESGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPSKIRS 518

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Xenopus
Match: mlxip (MLX interacting protein [Source:Xenbase;Acc:XB-GENE-990525])

HSP 1 Score: 356.295 bits (913), Expect = 1.327e-115
Identity = 217/537 (40.41%), Postives = 303/537 (56.42%), Query Frame = 2

Query:  119 ELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKF-------QDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQ-SPNSDIRDRLLKNKNYY---LEKISEEIVPNNDEN-------PG-FSDHYD----GNFYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 1651
            E+FT+   ++ +   E+DL + L +Y+  EE+RL+++  +A E+    +S+   +D    E Y  +P+N+Y   ++F  DW    +LV           LQ+    F       ++  P  +D  GA  A++R+Q+TY LD   +  GK+        L+ADD F +G  AY   ++   V W +++L      +   D  +N+  +LDYLSY +  +G    AL  T  LL   PN    DR + N  Y+    EK   E+  N   N       PG +S   D     + Y ALCRGE       R++ L C  +N    P+  + P+KVE  +  PR+V   + + DEEI  IK +A PKL RATVR+P TG+L  A+YR+SKSAWL  + D + +++N R+ A TGL ++ AE LQV NYG+GG Y PHFD  +K   D F+ +  GNR+AT L YMSDVEAGGATVF + GA +WPKKG+A FW+NL  +GE D  TRHA CPVLVGSKWV NKWFHERGQEF RPC L  +
Sbjct:   22 EVFTSTGQMTDLIFRERDLLQSLKEYIREEEERLSKIKRWASEVD--ELSSRSTADP---EGYLGHPVNAYKLVKRFNTDWSSLENLV-----------LQDSAKGFIANFTFQREYFPTEEDETGAARALMRIQDTYKLDPDVIAKGKLPGTNYISSLSADDSFGMGKIAYHDGDYYHTVLWMQQALKQMDEGE---DAVVNKVDVLDYLSYTVFQLGDVPRALELTKRLLVLDPN---HDRAVNNLKYFEKMQEKQKAELKQNESTNTESATRQPGVYSRPLDYLPERDVYEALCRGEGVKMNPRRQRRLFCRYHNGNRSPYLILSPVKVEDEWDSPRIVRYLNALSDEEIAKIKELAKPKLARATVRDPKTGVLSVANYRVSKSAWLEENDDPVIARVNLRMQAITGLTVDTAELLQVANYGMGGQYEPHFDFSRKDEPDVFKRLGTGNRVATFLNYMSDVEAGGATVFPDFGAAIWPKKGTAVFWYNLFRSGEGDYRTRHAACPVLVGSKWVSNKWFHERGQEFLRPCGLTEV 536

[Close]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Xenopus
Match: mlxip (MLX interacting protein [Source:Xenbase;Acc:XB-GENE-990525])

HSP 1 Score: 353.214 bits (905), Expect = 2.041e-114
Identity = 222/558 (39.78%), Postives = 310/558 (55.56%), Query Frame = 2

Query:   56 MDFKRFFLFSILVAIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKF-------QDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQ-SPNSDIRDRLLKNKNYY---LEKISEEIVPNNDEN-------PG-FSDHYD----GNFYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 1651
            M+ + F +F         L  + F  + DL  +F+ E+DL + L +Y+  EE+RL+++  +A E+    +S+   +D    E Y  +P+N+Y   ++F  DW    +LV           LQ+    F       ++  P  +D  GA  A++R+Q+TY LD   +  GK+        L+ADD F +G  AY   ++   V W +++L      +   D  +N+  +LDYLSY +  +G    AL  T  LL   PN    DR + N  Y+    EK   E+  N   N       PG +S   D     + Y ALCRGE       R++ L C  +N    P+  + P+KVE  +  PR+V   + + DEEI  IK +A PKL RATVR+P TG+L  A+YR+SKSAWL  + D + +++N R+ A TGL ++ AE LQV NYG+GG Y PHFD  +K   D F+ +  GNR+AT L YMSDVEAGGATVF + GA +WPKKG+A FW+NL  +GE D  TRHA CPVLVGSKWV NKWFHERGQEF RPC L  +
Sbjct:    1 MNSEMFVVFVKSTTFSWKLTEQDFCQMTDL--IFR-ERDLLQSLKEYIREEEERLSKIKRWASEVD--ELSSRSTADP---EGYLGHPVNAYKLVKRFNTDWSSLENLV-----------LQDSAKGFIANFTFQREYFPTEEDETGAARALMRIQDTYKLDPDVIAKGKLPGTNYISSLSADDSFGMGKIAYHDGDYYHTVLWMQQALKQMDEGE---DAVVNKVDVLDYLSYTVFQLGDVPRALELTKRLLVLDPN---HDRAVNNLKYFEKMQEKQKAELKQNESTNTESATRQPGVYSRPLDYLPERDVYEALCRGEGVKMNPRRQRRLFCRYHNGNRSPYLILSPVKVEDEWDSPRIVRYLNALSDEEIAKIKELAKPKLARATVRDPKTGVLSVANYRVSKSAWLEENDDPVIARVNLRMQAITGLTVDTAELLQVANYGMGGQYEPHFDFSRKDEPDVFKRLGTGNRVATFLNYMSDVEAGGATVFPDFGAAIWPKKGTAVFWYNLFRSGEGDYRTRHAACPVLVGSKWVSNKWFHERGQEFLRPCGLTEV 533

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Xenopus
Match: notch3 (notch 3 [Source:Xenbase;Acc:XB-GENE-6450008])

HSP 1 Score: 351.288 bits (900), Expect = 1.028e-113
Identity = 208/540 (38.52%), Postives = 308/540 (57.04%), Query Frame = 2

Query:   68 RFFLFSILVAIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVG-MYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFS-------DHY-DGNFYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 1651
            +  L   L+ +F+C + + FT++  ++ +   EKDL   L  Y+  EE++L ++ ++A +L     +A     + + E +  +P+N++   ++   +W    +L+   +++ F   L  +   F    PN +D  GA  A++RLQ+TY+LDT  +  G +   +    L A+DCF++G  AY   ++     W +++L+     +   + +L++  +LDYLSY +   G + +A       L   P     +  L+   Y + K S +   +  E            DH  +   Y  LCRGE     S R+K L C  ++    P   + P K E  + KPR+V  HD+I DEEI  +K +A P+L RAT+ NP TG+LE A YRISKSAWL    D + +++N+RI   TGL++  AE+LQV NYG+GG Y PHFD  +K   DAF E+  GNR+AT LFYMSDVEAGGATVF EVGA ++PKKG+A FW+NL  +GE D  TRHA CPVLVG+KWV NKW HERGQEF+RPC L  +
Sbjct:    3 KIHLVLPLLGLFSCAHADFFTSIGHMTDLLNTEKDLVTSLKDYIKAEEQKLAQIKKWADKLDHLTDTA-----TKDPEGFLGHPVNAFKLMKRLNTEWVKLENLILKDISDGFISNLTIQRQYF----PNDEDQTGAAKALLRLQDTYNLDTDTISKGNLPGVKHKTSLTAEDCFDLGKTAYTDADYYHTELWMEQALSQLDAGE---ESSLDKVMVLDYLSYAVYQQGDLDKALTLTKLLLELDPEHQRGNGNLRYFEYIMSKESNKSSSSPSEGAELGTRKGRPKDHLPERQKYEKLCRGEGVKMTSRRQKRLFCRYFDGNKDPLLILSPTKQEDEWDKPRIVRYHDIISDEEISKVKELAKPRLRRATISNPITGVLETAQYRISKSAWLSAYEDPVVARLNRRIEGVTGLDMSTAEELQVANYGMGGQYEPHFDFARKDEPDAFKELGTGNRVATWLFYMSDVEAGGATVFPEVGAAVYPKKGTAVFWYNLFESGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCNLSEL 530

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Mouse
Match: P4ha2 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide [Source:MGI Symbol;Acc:MGI:894286])

HSP 1 Score: 357.451 bits (916), Expect = 4.213e-116
Identity = 208/537 (38.73%), Postives = 303/537 (56.42%), Query Frame = 2

Query:   95 AIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPN--NDENPGFSDHY-----------DGNFYTALCRGESPIEVSEREKNLKCY----NKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 1651
             + + +  E FT++  ++ +  AEKDL + L +Y+L EE +L ++  +A +++   +++   +D    E Y ++P+N+Y   ++   DW    DLV    +  F   L  +   F    P  +D  GA  A++RLQ+TY LD   +  G++   +    L+ DDCF +G  AY + ++   V W ++ L      +   + T+ +  +LDYLSY +  +G    A+  T  LL    S   +R   N  Y+   + EE   +  N  + G +              + + Y +LCRGE       R+K L C     N++P     I P K E  +  P +V  +D++ DEEIE IK +A PKL RATVR+P TG+L  ASYR+SKS+WL  D D + +++N+R+   TGL ++ AE LQV NYG+GG Y PHFD  +   QDAF+ +  GNR+AT L YMSDVEAGGATVF ++GA +WPKKG+A FW+NL  +GE D  TRHA CPVLVG KWV NKWFHERGQEF RPC    +
Sbjct:   16 GVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLAKIKSWASKMEA--LTSRSAADP---EGYLAHPVNAYKLVKRLNTDWPALGDLVLQDASAGFVANLSVQRQFF----PTDEDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGLGRSAYNEGDYYHTVLWMEQVLKQLDAGE---EATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPS--HERAGGNLRYFERLLEEERGKSLSNQTDAGLATQENLYERPTDYLPERDVYESLCRGEGVKLTPRRQKKLFCRYHHGNRVPQLL--IAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDEQDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGTTEV 536

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Mouse
Match: P4ha2 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide [Source:MGI Symbol;Acc:MGI:894286])

HSP 1 Score: 352.829 bits (904), Expect = 2.527e-114
Identity = 207/536 (38.62%), Postives = 301/536 (56.16%), Query Frame = 2

Query:   95 AIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPN--NDENPGFSDHY-----------DGNFYTALCRGESPIEVSEREKNLKCY----NKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 1651
             + + +  E FT++  ++ +  AEKDL + L +Y+L EE +L ++  +A +++   +++   +D    E Y ++P+N+Y   ++   DW    DLV    +  F   L  +   F    P  +D  GA  A++RLQ+TY LD   +  G++   +    L+ DDCF +G  AY + ++   V W ++ L      +   + T+ +  +LDYLSY +  +G    A+  T  LL    S   +R   N  Y+   + EE   +  N  + G +              + + Y +LCRGE       R+K L C     N++P     I P K E  +  P +V  +D++ DEEIE IK +A PKL RATVR+P TG+L  ASYR+SKS+WL  D D + +++N+R+   TGL ++ AE LQV NYG+GG Y PHFD   +RP D+     GNR+AT L YMSDVEAGGATVF ++GA +WPKKG+A FW+NL  +GE D  TRHA CPVLVG KWV NKWFHERGQEF RPC    +
Sbjct:   16 GVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLAKIKSWASKMEA--LTSRSAADP---EGYLAHPVNAYKLVKRLNTDWPALGDLVLQDASAGFVANLSVQRQFF----PTDEDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGLGRSAYNEGDYYHTVLWMEQVLKQLDAGE---EATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPS--HERAGGNLRYFERLLEEERGKSLSNQTDAGLATQENLYERPTDYLPERDVYESLCRGEGVKLTPRRQKKLFCRYHHGNRVPQLL--IAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDF-SRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGTTEV 534

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Mouse
Match: P4ha2 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide [Source:MGI Symbol;Acc:MGI:894286])

HSP 1 Score: 352.829 bits (904), Expect = 2.527e-114
Identity = 207/536 (38.62%), Postives = 301/536 (56.16%), Query Frame = 2

Query:   95 AIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPN--NDENPGFSDHY-----------DGNFYTALCRGESPIEVSEREKNLKCY----NKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 1651
             + + +  E FT++  ++ +  AEKDL + L +Y+L EE +L ++  +A +++   +++   +D    E Y ++P+N+Y   ++   DW    DLV    +  F   L  +   F    P  +D  GA  A++RLQ+TY LD   +  G++   +    L+ DDCF +G  AY + ++   V W ++ L      +   + T+ +  +LDYLSY +  +G    A+  T  LL    S   +R   N  Y+   + EE   +  N  + G +              + + Y +LCRGE       R+K L C     N++P     I P K E  +  P +V  +D++ DEEIE IK +A PKL RATVR+P TG+L  ASYR+SKS+WL  D D + +++N+R+   TGL ++ AE LQV NYG+GG Y PHFD   +RP D+     GNR+AT L YMSDVEAGGATVF ++GA +WPKKG+A FW+NL  +GE D  TRHA CPVLVG KWV NKWFHERGQEF RPC    +
Sbjct:   16 GVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLAKIKSWASKMEA--LTSRSAADP---EGYLAHPVNAYKLVKRLNTDWPALGDLVLQDASAGFVANLSVQRQFF----PTDEDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGLGRSAYNEGDYYHTVLWMEQVLKQLDAGE---EATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPS--HERAGGNLRYFERLLEEERGKSLSNQTDAGLATQENLYERPTDYLPERDVYESLCRGEGVKLTPRRQKKLFCRYHHGNRVPQLL--IAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDF-SRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGTTEV 534

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Mouse
Match: P4ha1 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide [Source:MGI Symbol;Acc:MGI:97463])

HSP 1 Score: 339.347 bits (869), Expect = 4.373e-109
Identity = 209/528 (39.58%), Postives = 297/528 (56.25%), Query Frame = 2

Query:  122 LFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVG-MYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFSDHYDG--------------NFYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 1651
             FT++  ++ +   EKDL   L  Y+  EE +L ++ ++A++L     +A     + + E +  +P+N++   ++   +W +  +L+   +++ F   L  +   F    PN +D  GA  A+ RLQ+TY+LDT  +  G +   Q    L A+DCF +G  AY + ++     W +++L   +  ++    T+++ S+LDYLSY +   G + +A L     L   P      R   N  Y+   +S+E   N   +   SD                    Y  LCRGE       R+K L C  ++   +P + + P K E  + KPR++  HD+I D EIE +K +A P+L RAT+ NP TG LE   YRISKSAWL    D + S+IN RI   TGL++  AE+LQV NYG+GG Y PHFD  +K   DAF E+  GNRIAT LFYMSDV AGGATVF EVGA +WPKKG+A FW+NL A+GE D  TRHA CPVLVG+KWV NKW HERGQEF+RPC L  +
Sbjct:   21 FFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTA-----TKDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGFISNLTIQRQYF----PNDEDQVGAAKALFRLQDTYNLDTNTISKGNLPGVQHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALTQLEEGEL---STVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPE---HQRANGNLVYFEYIMSKEKDANKSASGDQSDQKTAPKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPVTGALETVHYRISKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSEL 533

[Close]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Mouse
Match: P4ha1 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide [Source:MGI Symbol;Acc:MGI:97463])

HSP 1 Score: 338.191 bits (866), Expect = 1.041e-108
Identity = 208/528 (39.39%), Postives = 298/528 (56.44%), Query Frame = 2

Query:  122 LFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVG-MYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFSDHYDG--------------NFYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 1651
             FT++  ++ +   EKDL   L  Y+  EE +L ++ ++A++L     +A     + + E +  +P+N++   ++   +W +  +L+   +++ F   L  +   F    PN +D  GA  A+ RLQ+TY+LDT  +  G +   Q    L A+DCF +G  AY + ++     W +++L   +  ++    T+++ S+LDYLSY +   G + +A L     L   P      R   N  Y+   +S+E   N   +   SD                    Y  LCRGE       R+K L C  ++   +P + + P K E  + KPR++  HD+I D EIE +K +A P+L+RATV +P TG L  A YR+SKSAWL    D + S+IN RI   TGL++  AE+LQV NYG+GG Y PHFD  +K   DAF E+  GNRIAT LFYMSDV AGGATVF EVGA +WPKKG+A FW+NL A+GE D  TRHA CPVLVG+KWV NKW HERGQEF+RPC L  +
Sbjct:   21 FFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTA-----TKDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGFISNLTIQRQYF----PNDEDQVGAAKALFRLQDTYNLDTNTISKGNLPGVQHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALTQLEEGEL---STVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPE---HQRANGNLVYFEYIMSKEKDANKSASGDQSDQKTAPKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSEL 533

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. UniProt/SwissProt
Match: sp|Q20065|P4HA2_CAEEL (Prolyl 4-hydroxylase subunit alpha-2 OS=Caenorhabditis elegans OX=6239 GN=phy-2 PE=1 SV=1)

HSP 1 Score: 372.474 bits (955), Expect = 4.497e-121
Identity = 224/531 (42.18%), Postives = 319/531 (60.08%), Query Frame = 2

Query:   86 ILVAIFNCL-YGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEID---KFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQ-SPNSDIRDRLLKNKNYYLEKI-SEEIVPNNDENPGFSDHYDG----NFYTALCRGESPIEVSEREKNLKCYNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLK 1645
            +LV +   L + +LFTA+ DL  +  AEKD++ ++ QY+  E  RL++L  +A E     +  N  ++S+  E + +NPIN+YL  ++   +WK    + N  +NNK    L+   D   + + + P  +D+ GA  A++RLQ+TY LDT DL  G I   + + KL+  D F +G  AY ++++   + W +  + L KI   +P  T+ E  IL+YL+Y L   G  R AL+ T  L + +PN     R   N  +Y + +  +++V +          YDG    + Y ALCRGE P    + +  L+CY K   PF K+ P+KVE+    P  V+  ++IHD EIE IK +ASPKL RATV+N  TG LE A+YRISKSAWL  DLD +  ++N+RI   T LN   +E+LQV NYG+GGHY PHFD  +K  ++AF+ +  GNRIAT+LFYMS  E GGATVF  +G  ++P K  A FW+NL+ +GE D  TRHA CPVL+G KWV NKW HE+GQEF RPC L+
Sbjct:    5 LLVCLLAGLAHADLFTAIADLQHMLGAEKDVTTIIDQYIEAERARLDDLRRYAHEY----VHRNAHAESVGPE-FVTNPINAYLLIKRLTTEWKK---VENIMLNNKASTFLKNITDNRVRSEVKFPGEEDLSGAATALLRLQDTYSLDTLDLSNGIIGGEKVSNKLSGHDTFEVGRSAYNQKDYYHCLMWMQ--VALVKIENENPP-TIEEWEILEYLAYSLYQQGNVRRALSLTKRLAKIAPN---HPRAKGNVKWYEDMLQGKDMVGDLPPIVNKRVEYDGIVERDAYEALCRGEIPPVEPKWKNKLRCYLKRDKPFLKLAPIKVEILRFDPLAVLFKNVIHDSEIEVIKELASPKLKRATVQNSKTGELEHATYRISKSAWLKGDLDPVIDRVNRRIEDFTNLNQATSEELQVANYGLGGHYDPHFDFARKEEKNAFKTLNTGNRIATVLFYMSQPERGGATVFNHLGTAVFPSKNDALFWYNLRRDGEGDLRTRHAACPVLLGVKWVSNKWIHEKGQEFTRPCGLE 521

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. UniProt/SwissProt
Match: sp|O15460|P4HA2_HUMAN (Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens OX=9606 GN=P4HA2 PE=1 SV=1)

HSP 1 Score: 356.681 bits (914), Expect = 5.010e-115
Identity = 212/544 (38.97%), Postives = 311/544 (57.17%), Query Frame = 2

Query:   68 RFFLFSILVAIF---NCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYY---LEKISEEIVPNNDENP-----GFSDHY-----DGNFYTALCRGESPIEVSEREKNLKCY----NKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPC 1636
            + ++ ++L+A F   +C+  E FT++  ++ +  AEK+L + L +Y+L EE +L+++  +A +++   +++   +D+   E Y ++P+N+Y   ++   DW    DLV       F   L  +   F    P  +D  GA  A++RLQ+TY LD   +  G++   +    L+ DDCF +G  AY + ++   V W ++ L      +   + T  +  +LDYLSY +  +G    AL  T  LL    S   +R   N  Y+   LE+  E+ + N  E       G  +       + + Y +LCRGE       R+K L C     N+ P     I P K E  +  P +V  +D++ DEEIE IK +A PKL RATVR+P TG+L  ASYR+SKS+WL  D D + +++N+R+   TGL ++ AE LQV NYG+GG Y PHFD  +   +D F+ +  GNR+AT L YMSDVEAGGATVF ++GA +WPKKG+A FW+NL  +GE D  TRHA CPVLVG KWV NKWFHERGQEF RPC
Sbjct:    2 KLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWANKMEA--LTSKSAADA---EGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQFF----PTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGE---EATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPS--HERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRAPQLL--IAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 529

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. UniProt/SwissProt
Match: sp|Q60716|P4HA2_MOUSE (Prolyl 4-hydroxylase subunit alpha-2 OS=Mus musculus OX=10090 GN=P4ha2 PE=1 SV=1)

HSP 1 Score: 355.91 bits (912), Expect = 1.024e-114
Identity = 207/537 (38.55%), Postives = 303/537 (56.42%), Query Frame = 2

Query:   95 AIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPN--NDENPGFSDHY-----------DGNFYTALCRGESPIEVSEREKNLKCY----NKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 1651
             + + +  E FT++  ++ +  AEKDL + L +Y+L EE +L ++  +A +++   +++   +D    E Y ++P+N+Y   ++   DW    DLV    +  F   L  +   F    P  +D  GA  A++RLQ+TY LD   +  G++   +    L+ DDCF +G  AY + ++   V W ++ L      +   + T+ +  +LDYLSY +  +G    A+  T  LL    S   +R   N  Y+   + EE   +  N  + G +              + + Y +LCRGE       R+K L C     N++P     I P K E  +  P +V  +D++ DEEIE IK +A PKL RATVR+P TG+L  ASYR+SKS+WL  D D + +++N+R+   TGL ++ AE LQV NYG+GG Y PHFD  +   +DAF+ +  GNR+AT L YMSDVEAGGATVF ++GA +WPKKG+A FW+NL  +GE D  TRHA CPVLVG KWV NKWFHERGQEF RPC    +
Sbjct:   16 GVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLAKIKSWASKMEA--LTSRSAADP---EGYLAHPVNAYKLVKRLNTDWPALGDLVLQDASAGFVANLSVQRQFF----PTDEDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGLGRSAYNEGDYYHTVLWMEQVLKQLDAGE---EATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPS--HERAGGNLRYFERLLEEERGKSLSNQTDAGLATQENLYERPTDYLPERDVYESLCRGEGVKLTPRRQKKLFCRYHHGNRVPQLL--IAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDDEDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGTTEV 536

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. UniProt/SwissProt
Match: sp|Q5ZLK5|P4HA2_CHICK (Prolyl 4-hydroxylase subunit alpha-2 OS=Gallus gallus OX=9031 GN=P4HA2 PE=2 SV=1)

HSP 1 Score: 348.591 bits (893), Expect = 5.912e-112
Identity = 212/526 (40.30%), Postives = 301/526 (57.22%), Query Frame = 2

Query:  116 GELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELL------QSPNSDIR--DRLLKNKNYYLEKISEEIVPNND---ENPGFSDHYD----GNFYTALCRGESPIEVSEREKNLKCY----NKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPC 1636
             E FT++  ++ +  AEKDL + L +Y+  EE +L+++  +A+++    +++   SD    E Y ++P+N+Y   ++   DW +  +LV     N F   L  +   F    P  +D  GA  A++RLQ+TY LD + L  G +   +    L   DCF +G  AY   ++   V W +++L   K +    D T+++  ILDYLSY +   G    A+  T  L+      +   S++R  ++LL+ +    EK S + V   +   ++  +    D     + Y ALCRGE       R+K L C     N+ PH    I P K E  +  P +V  +D++ DEEIE IK +A PKL RATVR+P TG+L  ASYR+SKS+WL  D D + +K+N+R+   TGL ++ AE LQV NYG+GG Y PHFD  + RP D+     GNR+AT L YMSDVEAGGATVF + GA +WPKKG+A FW+NL  +GE D  TRHA CPVLVG KWV NKWFHERG EF RPC
Sbjct:   21 AEFFTSIGQMTDLIYAEKDLVQSLKEYIRAEETKLSQIKSWAEKMDV--LTSKSTSDP---EGYLAHPVNAYKLVKRLNTDWLELENLVLQDTTNGFITNLTIQRQFF----PTEEDETGAAKALMRLQDTYKLDPETLSRGNLPGTKYRSSLTVSDCFGMGKTAYNDGDYYHTVLWMEQAL---KQHDEGEDTTVSKVEILDYLSYAVFQFGDLHRAMELTRRLISLDSTHERAGSNLRYFEKLLEKER---EKPSNKTVATTEPVVQSGAYERPLDYLPERDIYEALCRGEGVKMTPRRQKRLFCRYHDGNRNPHLL--IAPFKEEDEWDSPHIVRYYDVMSDEEIEKIKQLAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVAKVNQRMQQITGLTVKTAELLQVANYGMGGQYEPHFDFSR-RPFDSTLKSEGNRLATFLNYMSDVEAGGATVFPDFGAAIWPKKGTAVFWYNLFRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGNEFLRPC 528

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. UniProt/SwissProt
Match: sp|Q10576|P4HA1_CAEEL (Prolyl 4-hydroxylase subunit alpha-1 OS=Caenorhabditis elegans OX=6239 GN=dpy-18 PE=1 SV=2)

HSP 1 Score: 343.969 bits (881), Expect = 7.671e-110
Identity = 210/539 (38.96%), Postives = 298/539 (55.29%), Query Frame = 2

Query:   77 LFSILVAIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIE---KYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFS-------DHYDGN----FYTALCRGESPIEVSEREKNLKCYNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKN 1648
            L  +++A       +LFT++ D+  + + E+++ ++L +Y+ +EE+RL +L + ++E    N         + IE   K  +NPIN++L  ++ + DWK+    +N   N     +     D +  R P  DD+ GA   ++RLQ+TY LDTKDL  GKI   Q N   +A DCF I   AY + +F   V W +E+      ++V+P  T+    IL+YL++ L      + AL  T EL +   +  R +   N  +Y + + +E V  +D             D   GN     Y ALCR E P+   +  + L CY K   PF    P+KVE+    P  V+  D+I D+E+  I+ +A PKL RATV +  TG L  A+YRISKSAWL     ++   +NKRI   T L +E AE+LQ+ NYGIGGHY PHFDH KK    +FE +  GNRIAT+LFYMS    GG TVFTE  + + P K  A FW+NL   G+ +  TRHA CPVLVG KWV NKW HE+G EF+RPC LK+
Sbjct:    3 LALLVLATIGYAVADLFTSIADMQNLLETERNIPKILDKYIHDEEERLVQLKKLSEEYSKKN--------EISIENGLKDITNPINAFLLIKRKIFDWKEIESKMN--ANKAGNVVSSITDDSYGVRYPTADDLSGAAIGLLRLQDTYRLDTKDLADGKIYADQGNYTFSAKDCFEIARAAYNEHDFYHTVMWMEEAQRRLG-DEVEP--TVEVEDILEYLAFALYKQNNLKHALKLTEELYKMNPTHPRAK--GNVKWYEDLLEQEGVRRSDMRKNLPPIQNRRPDSVLGNTERTMYEALCRNEVPVSQKDISR-LYCYYKRDRPFLVYAPIKVEIKRFNPLAVLFKDVISDDEVAAIQELAKPKLARATVHDSVTGKLVTATYRISKSAWLKEWEGDVVETVNKRIGYMTNLEMETAEELQIANYGIGGHYDPHFDHAKKEESKSFESLGTGNRIATVLFYMSQPSHGGGTVFTEAKSTILPTKNDALFWYNLYKQGDGNPDTRHAACPVLVGIKWVSNKWIHEKGNEFRRPCGLKS 525

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. TrEMBL
Match: G4VTC9 (Putative prolyl 4-hydroxylase alpha subunit 1 OS=Schistosoma mansoni OX=6183 GN=Smp_068280 PE=4 SV=1)

HSP 1 Score: 436.417 bits (1121), Expect = 7.948e-143
Identity = 242/558 (43.37%), Postives = 342/558 (61.29%), Query Frame = 2

Query:  116 GELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSM-----EIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRK---------------------ILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLN-----LFKINKVDPDGTL--NERS------------ILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKI--SEEIVPNNDENPGFSDH-YDGNFYTALCRGESPIEVSEREKNLKCYNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLK 1645
             E +TA+VD++K ++  ++L   L+ Y+  EE RLN + +  K L + N S +D S ++     ++E+Y  NPIN+YL  ++    WK +L  + D V N F+K                      ++  + +  D LP  +D+ GA+DA++RLQ TY L  + L  G++ +  S  +L+A  C  +G HAY + +F  + +WF+ + +     L +  +VD  GT   N+ +            ILDYL+Y LG  G Y  ALN T  L++   ++ R   + N+ YY+E+I   E  +  N  +   S H  +   Y +LCR E+P        +L C    PH F+KIGP+K E     PR+V+ +DLI   EIE IK +A+P+L RATV+NP TGILE A YR SKSAWLP+ + EIT +I++RI A TGL++E AEDLQV NYG+GGHY+PHFD G+KR +DAFE++ GNRIAT++FY+SDV+AGGATVF  +G ++ PKKG+A FWFNL  NGE D  TRHA CPVL GSKWVMN WFHERGQEF+RPC+L+
Sbjct:   21 AEYYTAVVDITKAWRLSQELVSDLNSYIALEEGRLNRIRKVVKVLDS-NGSISDASSTLNQQNNDLEEYLGNPINAYLTMKRLSSSWKSQLSQLVDNVPNGFQKGDTDGSDYLNISDAQNTITMNTIRSRVKQHTDMLPGDNDVSGAVDAILRLQSTYKLPARRLAYGQLIDNLSTPQLSAAQCLEVGRHAYLQGDFEQSEEWFRVAYDRLFDELEEKREVDAQGTTIANDETEENGETEPTVGQILDYLAYSLGRQGRYAEALNVTRLLIEEEPTNTR--AINNEAYYVEQIDRGEGRIGPNPRSQAISKHDQETELYESLCRNENPFPTVP-SHHLTCRYYTPHAFFKIGPVKEETLNPDPRIVMWYDLIFPSEIEKIKELATPRLRRATVKNPVTGILEIAFYRTSKSAWLPHSMSEITDQISQRIRAVTGLSLETAEDLQVGNYGLGGHYAPHFDFGRKREKDAFEVKNGNRIATIIFYLSDVQAGGATVFNRIGTRVVPKKGAAGFWFNLLPNGEGDLRTRHAACPVLAGSKWVMNLWFHERGQEFRRPCELE 574

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. TrEMBL
Match: A0A1C9TA56 (Prolyl 4-hydroxylase subunit alpha-1-like protein OS=Saccoglossus kowalevskii OX=10224 PE=2 SV=1)

HSP 1 Score: 407.527 bits (1046), Expect = 2.538e-132
Identity = 236/549 (42.99%), Postives = 320/549 (58.29%), Query Frame = 2

Query:   65 KRFFLFSILVAIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKD-----KLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKIS--------EEIVPNNDENPGFSDHYDGN-------FYTALCRGESPIEVSEREKNLKC----YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPC 1636
            K     S+L+  F+    E FTAL DL ++   E ++ + L QY+L E+ +L+EL   A EL+  ++ A     S + E+Y  +P+N++L  ++ + DW       K    +++V N         I   Q+  P T+D+ GA++A+ RLQ+TY LD+ D+  G+I     +  LNA +CF +G  AY   +    V W KE+L     N      + +E +ILDYLSY    +G  + AL  TN LL      +R   L NK Y+ ++++        +  VP  +E      H   N        Y ALCRGE      +R+K LKC    YN+   PF  + P K EV F KP+L+I HD I   EI  +K++ASP+L RAT++N  TG LEFA YRISKSAWL  D  ++  ++N RI   TGL ++ AE+LQV NYG+GGHY PHFD  +K   +AF+ +  GNRIAT LFYMSDVEAGGATVF +VGA+L P+KGSAAFW+NL  NGE D  TRHA CPVLVGSKWV NKW HERGQEF+  C
Sbjct:    6 KGILACSVLLLCFSVGCCEFFTALSDLERLVHKESEMVQSLKQYILMEQAKLDELNRMASELEVMSLKA-----SKDPEEYLHHPVNAFLLVKRLLSDWNTIEETVKYSHADEYVRN---------ISDHQEWFPGTEDLTGAVNALFRLQDTYKLDSSDIAEGRIIGATDSPTLNAQECFELGRVAYVAGDNYHTVIWMKEALRQLTTN-----NSSDEATILDYLSYSTYMIGNIKEALRLTNSLLAIDPEHVRG--LGNKAYFEQELAKYNRQRGDDADVPGEEEKEFLESHKPLNDYLPEREAYEALCRGEQVKMSPQRQKKLKCRLRDYNR---PFLILQPAKEEVVFDKPKLIIFHDAILTNEIRKVKALASPRLRRATIQNSVTGNLEFAEYRISKSAWLSEDDGDVVHRLNHRIEQYTGLTMDTAEELQVANYGLGGHYEPHFDFARKEEINAFKSLNTGNRIATFLFYMSDVEAGGATVFPQVGARLIPEKGSAAFWYNLLKNGEGDYSTRHAACPVLVGSKWVSNKWIHERGQEFRHKC 530

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. TrEMBL
Match: A0A0P5JIY1 (Prolyl 4-hydroxylase subunit alpha-1 OS=Daphnia magna OX=35525 PE=4 SV=1)

HSP 1 Score: 394.43 bits (1012), Expect = 4.983e-127
Identity = 239/549 (43.53%), Postives = 323/549 (58.83%), Query Frame = 2

Query:   74 FLFSIL-VAIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKT-YNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISE--EIVPNNDENPGFSDHYDGNFYTA-------------------LCRGESPIEVSEREKNLKC-YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLK 1645
            FL +IL V      +GE+FTALVD+  +   E +L + L+ Y+  EE +L +L  + +E ++ Y  +  D S      KY +NP+N++L  ++   DWK   +++   V + F K L +       R P+ +D++GA  A++RLQ+TY LDT  L  G +     + +L A DC+ +G  +Y   +    V W  E+LN F     + + T+   SIL+YL++     G    AL  TNELL+  N     R L NK +Y + + +  EI+PN D   G  +     F TA                   LCRGE  +   E E  L C Y    +PF+ I PLK+EV F KP LVI H++I DEEI  +K +A P+  RAT+RNP TG LE A+YRISKSAWL  +  E   K+ +R+   TGL++  AEDLQVVNYGIGGHY PH+D+ +    +AF E+  GNRIAT LFYMSDVEAGGATVF  VGA LWP+KGSAAFW+NL  NG+ +++TRHA CPVL GSKWV NKW HE  QEF+RPC LK
Sbjct:    9 FLSTILFVMQTRNAFGEMFTALVDMEGLVSTEYELVKQLNNYIQEEETKLKQLRGYMEEYESMYQEAITDVS------KYLANPVNAFLLVKRLTSDWKKIEEVMTQNVGSAFVKNLTQHRTDL--RFPSDEDLNGAAVALMRLQDTYKLDTHALANGNLLGKTYSRQLTAGDCWELGRQSYNNGDHYHTVLWMGEALNKFDD---ESNKTVTRESILEYLAFSTFKQGNVMEALQLTNELLK--NVPYHQRALGNKKHYEQVLLDQGEILPNVD-TAGLENVIAKPFNTANLKLKKPHDHLEEREKFEKLCRGERLMS-PEMESRLHCSYVTNNNPFFFIQPLKMEVGFLKPLLVIYHEVISDEEIATVKRMAQPRFKRATIRNPKTGELEHANYRISKSAWLKTEEHEHIFKVTRRVGDITGLDMATAEDLQVVNYGIGGHYDPHYDYARGDRLNAFKELGWGNRIATWLFYMSDVEAGGATVFPTVGAALWPRKGSAAFWYNLHPNGDGNELTRHAACPVLTGSKWVSNKWIHEHNQEFRRPCGLK 542

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. TrEMBL
Match: A0A0P5NSW2 (Prolyl 4-hydroxylase subunit alpha-1 OS=Daphnia magna OX=35525 PE=4 SV=1)

HSP 1 Score: 394.815 bits (1013), Expect = 2.240e-126
Identity = 239/549 (43.53%), Postives = 323/549 (58.83%), Query Frame = 2

Query:   74 FLFSIL-VAIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKT-YNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISE--EIVPNNDENPGFSDHYDGNFYTA-------------------LCRGESPIEVSEREKNLKC-YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLK 1645
            FL +IL V      +GE+FTALVD+  +   E +L + L+ Y+  EE +L +L  + +E ++ Y  +  D S      KY +NP+N++L  ++   DWK   +++   V + F K L +       R P+ +D++GA  A++RLQ+TY LDT  L  G +     + +L A DC+ +G  +Y   +    V W  E+LN F     + + T+   SIL+YL++     G    AL  TNELL+  N     R L NK +Y + + +  EI+PN D   G  +     F TA                   LCRGE  +   E E  L C Y    +PF+ I PLK+EV F KP LVI H++I DEEI  +K +A P+  RAT+RNP TG LE A+YRISKSAWL  +  E   K+ +R+   TGL++  AEDLQVVNYGIGGHY PH+D+ +    +AF E+  GNRIAT LFYMSDVEAGGATVF  VGA LWP+KGSAAFW+NL  NG+ +++TRHA CPVL GSKWV NKW HE  QEF+RPC LK
Sbjct:   65 FLSTILFVMQTRNAFGEMFTALVDMEGLVSTEYELVKQLNNYIQEEETKLKQLRGYMEEYESMYQEAITDVS------KYLANPVNAFLLVKRLTSDWKKIEEVMTQNVGSAFVKNLTQHRTDL--RFPSDEDLNGAAVALMRLQDTYKLDTHALANGNLLGKTYSRQLTAGDCWELGRQSYNNGDHYHTVLWMGEALNKFDD---ESNKTVTRESILEYLAFSTFKQGNVMEALQLTNELLK--NVPYHQRALGNKKHYEQVLLDQGEILPNVD-TAGLENVIAKPFNTANLKLKKPHDHLEEREKFEKLCRGERLMS-PEMESRLHCSYVTNNNPFFFIQPLKMEVGFLKPLLVIYHEVISDEEIATVKRMAQPRFKRATIRNPKTGELEHANYRISKSAWLKTEEHEHIFKVTRRVGDITGLDMATAEDLQVVNYGIGGHYDPHYDYARGDRLNAFKELGWGNRIATWLFYMSDVEAGGATVFPTVGAALWPRKGSAAFWYNLHPNGDGNELTRHAACPVLTGSKWVSNKWIHEHNQEFRRPCGLK 598

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. TrEMBL
Match: A0A430Q6X2 (Prolyl 4-hydroxylase OS=Schistosoma bovis OX=6184 GN=DC041_0007604 PE=4 SV=1)

HSP 1 Score: 394.045 bits (1011), Expect = 2.394e-126
Identity = 225/582 (38.66%), Postives = 330/582 (56.70%), Query Frame = 2

Query:   74 FLFSILVAIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSM-----EIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRK---------------------ILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLN-----LFKINKVDPDGTL--------------NERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISE---EIVPNNDENPGFSDHYDGNFYTALCRGESPIEVSEREKNLKCYNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISK----------SAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLK 1645
            F  + L+     +  E +TA++D++K ++  ++L   L+ Y+  EE+RLN + +  K L   N S +D S ++     ++E+Y  NPIN+YL  ++    WK ++  + D V N F+K                      ++  + +  D LP  +D+ GA+DA++RLQ TY L  + L  G++ +  S  +L+A  C  +G HAY + +F  + +WF+ + +     L +  +VD  GT                   ILDYL+Y LG  G Y  ALN T  L++   ++ R   + N+ +Y+E+I      I PN           +   Y +LCR E+P       ++L C    PH F++IGP+K E     PR+V+ +DLI   EIE IK +A+P+         ST +  F  Y +S           SAWLP+ + EIT +I++RI A TGL++E AEDLQV NYG+GGHY+PHFD G+KR +DAFE++ GNRIAT++FY+SDV+AGGATVF  +G ++ PKKG+A FWFNL  +GE D  TRHA CPVL GSKWVMN WFHERGQEF RPC+L+
Sbjct:    6 FTITWLLLFQQNINAEYYTAVIDITKAWRLSQELVSDLNSYIALEERRLNRIRKVVKVLDA-NGSISDASSTLSQQNNDLEEYLGNPINAYLTMKRLSSSWKSQISQLVDNVPNGFQKGDTDGSDYLNISDAQNTITMNTIRSRVKQHTDMLPGDNDVSGAVDAILRLQSTYKLPARQLAYGQLIDNLSTPQLSAAQCLEVGRHAYSQGDFEQSEEWFRVAYDRLFDELEQKKEVDAQGTTIASDETEENGETEPTVGQILDYLAYSLGRQGRYAEALNVTRLLIEEEPTNTR--AINNEAFYVEQIDRGEGRIGPNPRSQATSKHDQETELYESLCRNENPFPTVP-SRHLTCQYYTPHAFFRIGPIKEETLNPDPRIVMWYDLIFPSEIEKIKELATPR---------STIMSSFEQYFLSPTSLTCGPFSFSAWLPHSMTEITDQISQRIRAVTGLSLETAEDLQVGNYGLGGHYAPHFDFGRKREKDAFEVKNGNRIATIIFYLSDVQAGGATVFNRIGTRVVPKKGAAGFWFNLLPSGEGDLRTRHAACPVLAGSKWVMNLWFHERGQEFHRPCELE 574

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Cavefish
Match: p4ha1b (prolyl 4-hydroxylase subunit alpha-1-like [Source:NCBI gene;Acc:103026899])

HSP 1 Score: 346.665 bits (888), Expect = 4.797e-112
Identity = 204/529 (38.56%), Postives = 291/529 (55.01%), Query Frame = 2

Query:  119 ELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQ-SPNSDIRDRLLKNKNYYLEKI--SEEIVPNNDENPGFSDHYDGN---------------FYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKL 1642
            + FT++  ++ +   EKDL   L  Y+  EE +L E+ ++A++L +   +A       + E +  +P+N++   ++   +W D  +LV     + F   L  +   F    P  +D  GA  A++RLQ+TY L ++ +  G +       ++  +DCF +G  AY   ++     W  ++L+     +  P   +++ +++DYLSY +   G    AL  T  +L+  P     +  LK   + LEK   +EE      +  G   H D                  Y  LCRGE       R   L C   +    P   + P+K E  + +P +V  HD+I D EI  +K +A P+L RAT+ NP TG+LE A YRISKSAWL  D   +  +IN+RI   TGL ++ AE+LQV NYG+GG Y PHFD G+K   DAF E+  GNR+AT LFYMSDV AGGATVFT+VGA +WPKKG+A FW+NL A+GE D  TRHA CPVLVG+KWV NKW HERGQEF+RPC L
Sbjct:   20 DFFTSIGQMTDLLYTEKDLVTSLKDYIRAEESKLQEVKQWAEKLDSLTSTA-----VQDPEGFLGHPVNAFKLMKRLNSEWSDLENLVLKDTTDGFISNLTVQRQHF----PTDEDQTGAAKALLRLQDTYQLSSRAISAGDLPGVIHKSRMTVEDCFELGKIAYSDVDYYHTELWMTQALHQLDEGEESP---IDKVTVMDYLSYAIYQQGEIDRALELTKRMLKLDPTHQRANGNLKYFEFQLEKQRKAEEEAGKEAQKEGEKKHMDKRDVQMKRSKDPLPERKKYEQLCRGEGIKMTPRRWSRLFCRYQDNGRTPSLILAPVKEEDEWDRPHIVRFHDIISDYEISKVKELAKPRLRRATISNPITGVLETAPYRISKSAWLTADEHPVIERINQRIEDLTGLEMDTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRVATWLFYMSDVSAGGATVFTDVGAAVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCGL 536

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Cavefish
Match: p4ha1a (prolyl 4-hydroxylase subunit alpha 1 [Source:NCBI gene;Acc:103044793])

HSP 1 Score: 346.28 bits (887), Expect = 5.913e-112
Identity = 209/545 (38.35%), Postives = 313/545 (57.43%), Query Frame = 2

Query:   71 FFLFSILVAIFNC---LYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNV----KLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELL------QSPNSDIRD---RLLKNKNYYLEK--ISEEIVPNNDENPGFSDHYDGNFYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKL 1642
            + ++ +L+  + C    + + FT++  ++ +   EKDL   L  Y+  EE +L  + ++A++L     +A     + + E +  +P+N++   ++   +W +  DLV   +++ F   L  +   F    PN +D  GA  A++RLQ+TY LDT  +  G +    S++     L  DDCF +G  AY   ++     W  ++L   +++K + + +++  ++LDYLSY +   G    AL +T  LL      Q  N +++    +L K +    E+   +EE    + E   F    +   Y  LCRGE       R+  L C  ++   HP+Y +GP+K E  + +PR+V  H++I D+E+E +K ++ P+L RAT+ NP TG+LE A YRISKSAWL      +  +IN+RI   TGL++  AE+LQV NYG+GG Y PHFD G+K   DAF E+  GNRIAT LFYMSDV AGGATVF EVGA + P KG+A FW+NL  +GE D  TRHA CPVLVG+KWV NKW HERGQEF+R C L
Sbjct:    4 WCVWYVLLIGYLCKCSAHNDFFTSIGQMTDLLFTEKDLVTSLKDYIKAEESKLELVKQWAEKLDALTATA-----TQDPEGFLGHPVNAFKLMKRLNTEWGEVEDLVLKDMSDGFISNLTIQRQYF----PNDEDQTGAAKALLRLQDTYRLDTHTISSGNLPGVTSDLPYKSTLTVDDCFELGKIAYSDADYYHTELWMGQALR--QLDKGE-ESSIDSVTVLDYLSYSVYQQGELEKALEHTKRLLTLDSEHQRANGNLKYFEYQLAKQRKAEKEQKGTTEERTKRDTEKNSFLP--EKRKYEKLCRGEGLRLTPRRQSRLFCRFHDNNRHPYYILGPVKQEDEWDRPRIVRYHNIISDKEMEKVKELSKPRLRRATISNPITGVLETAHYRISKSAWLAAYEHPVVDRINQRIQDITGLDVTTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVAAGGATVFPEVGAAIKPMKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRRCSL 534

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Cavefish
Match: p4ha2 (prolyl 4-hydroxylase subunit alpha 2 [Source:NCBI gene;Acc:103035211])

HSP 1 Score: 341.658 bits (875), Expect = 4.067e-110
Identity = 202/555 (36.40%), Postives = 311/555 (56.04%), Query Frame = 2

Query:   77 LFSILVAIFNC-LYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLV-----NDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKI--QNFQSNVKLNA----DDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFSDHYD---GNF------------YTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 1651
            +F   V    C ++ E+FT++  ++ +   E++L + L +Y+  EE +L  +  +A +L+    ++     + + E + ++P+N+Y   ++   +W +   LV     + F++N         I   +   P+ +D +GA  A++RLQ+TY+LD++    GK+  Q   S V+ NA    DDCF++G  AY + ++  AV W +++L   +      +  + +  ILDYLSY +  +G    A+  T  L+    S    R   N  Y+   +S+E+   +   P  ++      G +            Y ALCRGE      +R   L C   ++  +P   + P+K E  +  P +V   + + DEE+  IK +A PKL RATVR+P TG+L  A YR+SKSAWL ++ D +  ++N+RI   TGL ++ AE LQV NYG+GG Y PHFD  +K   DAF+ +  GNR+AT L YMSDV+AGGATVF + GA +WP+KG+A FW+NL  +GE D  TRHA CPVL+GSKWV NKW HERGQEF+RPC L  +
Sbjct:    6 VFVWTVCCITCSVHAEIFTSIGQMTDLLFTERELVQSLKEYIQAEESKLAAVKRWADKLEVLTRAS-----TSDPEGFLAHPVNAYKLVKRLNTEWSELESLVLHDPSDGFISN---------ISVHRQVFPDQEDENGAAKALMRLQDTYNLDSESFSKGKLPGQGQYSGVRYNAFLTVDDCFDMGKTAYNENDYYHAVLWMQQAL---RQKDAGEEAKVPKAEILDYLSYSVYQMGDLPRAIELTRRLVSIDPS--HQRAGGNLRYFERLLSKELREMDQNRPEPTEEKPIQLGTYERPRDYLPEREAYEALCRGEGIRMTPQRSSRLFCRYQDRNRNPRLLLKPMKEEDEWDSPHIVRYLEALSDEEMNRIKELAKPKLARATVRDPKTGVLTTAQYRVSKSAWLEDEDDLVIRRVNQRIEDVTGLTVDTAELLQVANYGVGGQYEPHFDFSRKDEPDAFKSLGTGNRVATYLNYMSDVDAGGATVFPDFGAAIWPRKGTAVFWYNLFRSGEGDYRTRHAACPVLIGSKWVSNKWIHERGQEFRRPCGLTEV 541

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Cavefish
Match: p4ha1b (prolyl 4-hydroxylase subunit alpha-1-like [Source:NCBI gene;Acc:103026899])

HSP 1 Score: 341.273 bits (874), Expect = 6.841e-110
Identity = 202/529 (38.19%), Postives = 289/529 (54.63%), Query Frame = 2

Query:  119 ELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQ-SPNSDIRDRLLKNKNYYLEKI--SEEIVPNNDENPGFSDHYDGN---------------FYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKL 1642
            + FT++  ++ +   EKDL   L  Y+  EE +L E+ ++A++L +   +A       + E +  +P+N++   ++   +W D  +LV     + F   L  +   F    P  +D  GA  A++RLQ+TY L ++ +  G +       ++  +DCF +G  AY   ++     W  ++L+     +  P   +++ +++DYLSY +   G    AL  T  +L+  P     +  LK   + LEK   +EE      +  G   H D                  Y  LCRGE       R   L C   +    P   + P+K E  + +P +V  HD+I D EI  +K +A P+L RATV +P TG L  A YR+SKSAWL  D   +  +IN+RI   TGL ++ AE+LQV NYG+GG Y PHFD G+K   DAF E+  GNR+AT LFYMSDV AGGATVFT+VGA +WPKKG+A FW+NL A+GE D  TRHA CPVLVG+KWV NKW HERGQEF+RPC L
Sbjct:   20 DFFTSIGQMTDLLYTEKDLVTSLKDYIRAEESKLQEVKQWAEKLDSLTSTA-----VQDPEGFLGHPVNAFKLMKRLNSEWSDLENLVLKDTTDGFISNLTVQRQHF----PTDEDQTGAAKALLRLQDTYQLSSRAISAGDLPGVIHKSRMTVEDCFELGKIAYSDVDYYHTELWMTQALHQLDEGEESP---IDKVTVMDYLSYAIYQQGEIDRALELTKRMLKLDPTHQRANGNLKYFEFQLEKQRKAEEEAGKEAQKEGEKKHMDKRDVQMKRSKDPLPERKKYEQLCRGEGIKMTPRRWSRLFCRYQDNGRTPSLILAPVKEEDEWDRPHIVRFHDIISDYEISKVKELAKPRLRRATVHDPITGKLTTAQYRVSKSAWLTADEHPVIERINQRIEDLTGLEMDTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRVATWLFYMSDVSAGGATVFTDVGAAVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCGL 536

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Cavefish
Match: p4ha2 (prolyl 4-hydroxylase subunit alpha 2 [Source:NCBI gene;Acc:103035211])

HSP 1 Score: 316.235 bits (809), Expect = 2.102e-100
Identity = 190/561 (33.87%), Postives = 296/561 (52.76%), Query Frame = 2

Query:   35 VLSYSIWMDFKRFFLFSILVAIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLV-----NDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFSDHYD---GNF------------YTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 1651
            V  +  W+    F +F   + +F+  Y  L   L  ++ +   E++L + L +Y+  EE +L  +  +A +L+    ++     + + E + ++P+N+Y   ++   +W +   LV     + F++N         I   +   P+ +D +GA  A++RLQ+TY+LD++    GK+   + N  L  DDCF++G  AY + ++  AV W +++L   +      +  + +  ILDYLSY +  +G    A+  T  L+    S    R   N  Y+   +S+E+   +   P  ++      G +            Y ALCRGE      +R   L C   ++  +P   + P+K E  +  P +V   + + DEE+  IK +A PKL RATVR+P TG+L  A YR+SKSAWL ++ D +  ++N+RI   TGL ++ AE LQV NYG+GG Y PHFD  +                     MSDV+AGGATVF + GA +WP+KG+A FW+NL  +GE D  TRHA CPVL+GSKWV NKW HERGQEF+RPC L  +
Sbjct:    6 VREWGEWVTNAIFLVFKYFLLMFSITY--LPLQLGQMTDLLFTERELVQSLKEYIQAEESKLAAVKRWADKLEVLTRAS-----TSDPEGFLAHPVNAYKLVKRLNTEWSELESLVLHDPSDGFISN---------ISVHRQVFPDQEDENGAAKALMRLQDTYNLDSESFSKGKLPGVRYNAFLTVDDCFDMGKTAYNENDYYHAVLWMQQAL---RQKDAGEEAKVPKAEILDYLSYSVYQMGDLPRAIELTRRLVSIDPS--HQRAGGNLRYFERLLSKELREMDQNRPEPTEEKPIQLGTYERPRDYLPEREAYEALCRGEGIRMTPQRSSRLFCRYQDRNRNPRLLLKPMKEEDEWDSPHIVRYLEALSDEEMNRIKELAKPKLARATVRDPKTGVLTTAQYRVSKSAWLEDEDDLVIRRVNQRIEDVTGLTVDTAELLQVANYGVGGQYEPHFDFSR---------------------MSDVDAGGATVFPDFGAAIWPRKGTAVFWYNLFRSGEGDYRTRHAACPVLIGSKWVSNKWIHERGQEFRRPCGLTEV 524

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Sea Lamprey
Match: p4ha1b (prolyl 4-hydroxylase, alpha polypeptide I b [Source:ZFIN;Acc:ZDB-GENE-030131-4089])

HSP 1 Score: 113.62 bits (283), Expect = 9.157e-28
Identity = 97/363 (26.72%), Postives = 164/363 (45.18%), Query Frame = 2

Query:   74 FLFSILVAIFNCLYG--ELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRL-------PNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQN-----FQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNEL-LQSPNSDIRDRLLKNKNYYLEKISE--------------EIVPNNDENPGFSDHYDGNFYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLV 1069
            FL  +L+A     +G  E+FT++  ++ +   E++L   L +++  +E RL  +  + KE+K     A     + + E +  NPIN+Y    +    W                  LQE  + F  RL       P+ +D  GA  A++RLQ+TY LD + L  GK+         S   L+ADDCF++G  AY +  +  A  W   +L+      V  +GT+    +LDYLSY +  +G  + ALN T  L +  P+     R   N +Y+  ++++              ++   +D+   FS+  +   Y  LCR  S +    R++ L C  ++   HP   + PL  E  + +PR+V
Sbjct:    7 FLKWLLLAALVMQHGTAEVFTSIGHMTDLLYVEQELLSSLEKHIAEQELRLQRVKRW-KEMK----EAESHVATSDPEGFLGNPINAY-HTMRMGQRWA------------ALENFLQESAEGFVSRLAERRALFPSEEDRVGAARALLRLQDTYALDAELLASGKLPGGLCVPLVSASALSADDCFSLGRLAYSEGRYARAEPWLGHALS---QEGVGDEGTVGASDVLDYLSYSVYRLGDVQRALNLTRRLAVLDPD---HPRAQANLHYFEYEMAQAAATEEATTDDAEGDVAAADDDEEYFSEKEE---YELLCRSASGLMTPRRQRLLSCRYWDGRRHPLLILAPLMEEDEWDRPRIV 342

[Close]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Sea Lamprey
Match: p4ha1b (prolyl 4-hydroxylase, alpha polypeptide I b [Source:ZFIN;Acc:ZDB-GENE-030131-4089])

HSP 1 Score: 89.3521 bits (220), Expect = 1.852e-20
Identity = 66/225 (29.33%), Postives = 104/225 (46.22%), Query Frame = 2

Query:  143 LSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRL-------PNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQN--FQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNEL 790
            ++ +   E++L   L +++  +E RL  +  + KE+K     A     + + E +  NPIN+Y    +    W                  LQE  + F  RL       P+ +D  GA  A++RLQ+TY LD + L  GK+      S   L+ADDCF++G  AY +  +  A  W   +L+      V  +GT+    +LDYLSY +  +G  + ALN T  L
Sbjct:    4 MTDLLYVEQELLSSLEKHIAEQELRLQRVKRW-KEMK----EAESHVATSDPEGFLGNPINAY-HTMRMGQRWA------------ALENFLQESAEGFVSRLAERRALFPSEEDRVGAARALLRLQDTYALDAELLASGKLPGVPLVSASALSADDCFSLGRLAYSEGRYARAEPWLGHALS---QEGVGDEGTVGASDVLDYLSYSVYRLGDVQRALNLTRRL 207

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002062.1 (pep scaffold:Pmarinus_7.0:GL478223:560729:563134:-1 gene:ENSPMAG00000001867.1 transcript:ENSPMAT00000002062.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.8322 bits (120), Expect = 1.150e-7
Identity = 41/164 (25.00%), Postives = 60/164 (36.59%), Query Frame = 2

Query: 1250 KRITASTGLN---IEMAEDLQVVNYGIGGHYSPHFD-----------HGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVF---------------------------TEVGAKLWPKKGSAAFWFNLKANG-----ESDDMTRHAGCPVLVGSKWVMNKWF 1603
            +R+   TGL    +E  E +QV     GGH   H D           H +   Q     E   R  T+L +++DVE GG T F                           +    ++ P  GSA  W+N  ++G     E DD +    C V+ G++W    W 
Sbjct:    2 RRVVHLTGLPRALVEAGEPVQVHVLAEGGHERAHRDSGATDARTVCAHTRMLAQHHHTAETPCRYVTVLVFLNDVEEGGETAFPAADNRTFDSSDLVRGDVDLSDMRAHCSRANLRVTPHAGSALLWYNHLSDGRGWVGELDDYSLQGDCAVVRGARWTARLWV 165

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Nematostella
Match: EDO30487 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0N3])

HSP 1 Score: 335.88 bits (860), Expect = 2.182e-108
Identity = 211/541 (39.00%), Postives = 305/541 (56.38%), Query Frame = 2

Query:   86 ILVAIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKE---LKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLV--NDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPD----GTLNERSILDYLSYCLGSVGMYRAALNYTNELLQ-SPNSDIRDRLLKNKNYYLEKISEEI-----VPNNDENPGFSDHYDGNFYTALCRGESPIEVSEREKNLKCYNKIP-HPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWL--PNDLDE--ITSKINKRITASTGLNI--EMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKL 1642
            +LV       GELFTAL  +  + + EK L   L +Y LN   R +E +    E     T NI  +       +EK+  +P+N+Y+  R+F+ +WKD  + +  +D   +    +   ++D      P + D+ G + A+ R+Q+ Y++  K +  G + +  S   ++AD CF IG   ++ E    A +W +ESL      ++DP     G+L ++ IL+++++          AL +T+ELLQ  PN+D   R   N  ++L++   +       PN  + P     +    Y  LCRG S    +E    L+CY     HP ++I PLKVE   S P + ++ D+++D EIE+IK  A+PKL RATV N  TG LEFA YRISKS WL  P D +E  I +++N+R +  TGL+     AE LQ+VNYG  GHY PHFDH  +      ++  GNRIAT+L+YMSDVEAGGATVF +  A + P KG AAFW+NL  NG+ D+ TRHA CP++VGSKWV NKW HE GQEF+RPC L
Sbjct:    9 LLVCASTLACGELFTALTHMRGLIRLEKTLQRKLVEY-LNLNPRASEDLRITMEEVKQHTKNIRGD-------VEKFLGHPVNAYMLIRRFIKNWKDVEEYLEKHDDQEDLLALLRLHKVD-----FPTSKDMLGCVQAIQRIQDVYNITAKRIASGHLSDITSTPPMSADSCFEIGYAHHRWEKHEEARQWMEESLR-----RLDPPFRYRGSLQKQDILEFIAWSEYMTEREDLALAHTSELLQLDPNNDFAAR---NLEFFLQEYQAKANGSTKKPNIFKKPPPPREHFMEAYERLCRGIS-YRSNEEAAKLRCYYDFTRHPMFRIRPLKVEELHSDPPIWMLRDVMYDSEIEYIKRTATPKLRRATVTNLKTGELEFADYRISKSGWLEDPRDDNEEKILNRVNRRTSIITGLDTTPRSAEALQIVNYGAAGHYEPHFDHATEAVSSILKLGIGNRIATVLYYMSDVEAGGATVFVDAEAIVKPSKGDAAFWYNLHKNGKGDERTRHAACPIIVGSKWVCNKWIHEHGQEFRRPCGL 527

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Nematostella
Match: EDO36261 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJ24])

HSP 1 Score: 329.717 bits (844), Expect = 6.058e-106
Identity = 191/533 (35.83%), Postives = 284/533 (53.28%), Query Frame = 2

Query:  164 EKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFSD----------------HYDGNF--YTALCRGESPIEVSEREKNLKCYNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTG----------------------ILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKL 1642
            EK+L E L +YV  EE RL ++ +F  ++ T +  A  + D   I  +  +P+NS+   ++F   W      + +       ++  E + K +D+ P+ +D+DGAI A++RLQ+TY L    +  G++   ++   +   D F+IG  AY   +      W + +L   KI K +    +    + D+L++     G ++ ALNY+ E+++   +  R     N  Y+  +I+++     D                       H    F  Y  LCRGE        +  + C+     P   + P ++E  F KP ++I  + I D EI+ IK +A+P+L RATV++P TG                       LEFA+YRISKS WL ++ DE+  +I+ R+ A +GLN+  +EDLQVVNYGIGGHY PH+D  +        +  GNRIAT L Y+SDVEAGG TVFT VGA +WP+KG AAFW+NLK +G+ D  TRHA CPVLVGSKWV NKW HE GQEF++PC +
Sbjct:    5 EKELQEALKRYVEVEESRLAQIKKFLAKVDTAHELATKYGD---IGGFLGHPVNSFALIKRFHKGW----SRMEELALKDTSEVFVETLTKHKDQFPSQEDVDGAITALLRLQDTYRLTPDVISTGRLPKVRAVPMMTVSDTFDIGRSAYLSNDMFYTKAWMEVALE--KIKKGEDSEDVKLFDVYDHLAFAEYQRGNFKKALNYSEEMVKIDPTHTR--ATDNVAYFGSEIAKQTKKRGDTGTSRRTKSPSSTFKKLKEREYFHRTKAFQNYEKLCRGEVRSLTKWEQGQMSCWQIRDDPLTVLKPGRIERVFVKPEVLIFRNFITDSEIKRIKELATPRLKRATVKDPVTGELIFANYRISKRRATIQHPVTGKLEFANYRISKSGWLRDEEDELVKRISYRVQAYSGLNMTTSEDLQVVNYGIGGHYEPHYDFARDGEDKFTSLGTGNRIATFLSYLSDVEAGGGTVFTRVGATVWPQKGDAAFWYNLKRSGDGDSSTRHAACPVLVGSKWVANKWIHEVGQEFRKPCSV 526

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Nematostella
Match: EDO46235 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQV7])

HSP 1 Score: 268.47 bits (685), Expect = 5.829e-83
Identity = 177/521 (33.97%), Postives = 263/521 (50.48%), Query Frame = 2

Query:  116 GELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQ-NFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPNNDE---NPGFSDHYDGNFYTALCRGESPI-EVSEREKNLKCY----NKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPN-DLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLK 1645
             E+++AL    ++   E +L++ L  Y+  +E RL  +  FA E+K     + D S       Y  +P+N YL  ++FV++W     +V +  N++    L + +   + + P ++D+ GAI A+ RLQE Y L   D   G+     ++   L   D + IG  +Y   +     +W  E+L L  +   +         +LD+L++     G  R ALN+T EL++    + R +   N  ++ +++  +  P N     N  F       F   + R ES   +  E +KN+  Y    +++    ++     VE    K RL               +    P LNRATV NP TG LE A YRISK+ WL   +  E+  ++ +RI A T LN+E AE  QV NYG+ G Y PHFD  +     +   +  GNRIAT+L +MS VE+GGATVF  VGA++ P+KG A FW NL  +G+ D  TRHAGCPVL G KWV NKW HE G EF RPC L+
Sbjct:    2 AEVYSALSHTQRIRDIELELNDALQDYIEEQETRLAAIKRFATEVK----HSVDLSAEGSPGSYIGHPVNMYLMIKRFVNEWPQVEKVVEEQSNSE--AFLLDRLASSKSKFPTSEDLTGAITAIKRLQEVYALKPVDFSEGRFGFKPKTGYLLGPKDTYKIGRESYLDGDMVGTAEWMTETLRLMDLGVSNGAQAPRRTDVLDHLAFAEFKNGDGRKALNHTLELIKIDPENTRAK--NNLAFFTQEMKRDENPENTRAKNNLAF-------FTQEMKRDESKFTKKEEEKKNVPSYKWMKSRLSQDVFENFNWHVERDIYK-RLC--------------RGEKLPTLNRATVHNPITGHLETAHYRISKNCWLSGREHGEVIDRVERRIAAMTRLNLETAEGFQVQNYGLAGQYDPHFDFSRDLANSSLGSLGTGNRIATVLVWMSQVESGGATVFPYVGARILPQKGDAVFWHNLLRSGDGDFRTRHAGCPVLSGIKWVANKWIHEYGNEFHRPCSLR 492

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Nematostella
Match: EDO36263 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJ26])

HSP 1 Score: 263.848 bits (673), Expect = 7.150e-81
Identity = 177/530 (33.40%), Postives = 274/530 (51.70%), Query Frame = 2

Query:   98 IFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQ-SNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLF----KINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELL-QSPN-----SDIRD-RLLKNKNYYLEKISEEIVPNNDENPGFSD--HYDGNFYTALCRGESPIEVSEREKNLKCYNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKL 1642
            + + +  E+FT++  L ++   EK+L E L  Y++ E KRL       ++LK    +  +     E +    +P++ +    +   +W     LV     N  +    +EI  +    P+  D DG   AM+RLQ+ Y++ ++ +  G I   + ++ +L+  D + IG  AY+  N   A  W + +L +      +  +     ++   +L++L++    +G    +L +  E+L   PN     S+IR  + L  K  +L   S     N  E+ G  +    +   YT LCR  S   +    K L C     HP  K+ P+ +E+    P++ + H+++ + EIE +  +A P+L RA V N  TG +E   YRIS+ AWL +   +I  +IN+R+   TGLN    E LQV NYG+GGHY PHFDH           + +GNRIAT +FY+S+VEAGG+TVF + G K  P KG A FW+NLK +GE D  + HAGCPVL+G+KWV NKW HE G EF R C L
Sbjct:    2 LLSTITAEIFTSMDQLQRLSTVEKNLHETLDLYIMQERKRL-------EDLKGIYAAKKEELKKRERDDEVYHPLDVFRVINRVSSEWSTVEKLVR---FNPHKSEFIQEIRNYHASFPSDADFDGTRAAMLRLQKVYNISSQSISSGVIPGQRNAHARLSGIDSYQIGRKAYEDGNIIQAKAWMENTLRMMGTSESLQNLTGHVVVSRNDVLNHLAFLEYKIGDLARSLRFYREMLVNDPNDTELQSNIRKLKHLIAKQPHLNVTSPPNTANRIEDDGDDELSREEMAEYTRLCRPNSQTRLPSSNKQLTCSYLNKHPGLKLKPVAMEIVSVNPQITLFHNVLSEMEIEQMLELARPRLRRARVNNLETGEIEDVDYRISQIAWLSDSDGDIVRRINRRVGFITGLNTNTGECLQVNNYGVGGHYEPHFDHSLDMENSPIASLGQGNRIATFMFYLSEVEAGGSTVFIKTGVKTNPFKGGAVFWYNLKKSGEGDWDSLHAGCPVLIGNKWVANKWLHEHGNEFTRQCGL 521

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Nematostella
Match: EDO36288 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJ23])

HSP 1 Score: 233.802 bits (595), Expect = 5.665e-70
Identity = 166/473 (35.10%), Postives = 254/473 (53.70%), Query Frame = 2

Query:  122 LFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYN----ISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTD--DIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNER-SILDYLSYCLGSVGMYRAALNYTNELLQ--SPNSDIRDRL---LKNKNYYLEKISEEIVPNNDENPGFSDHYDGNFYTALCRGESPIEVSERE----KNLKC-YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKK 1489
            +F +L  L  + + E +L + L  YV  + +    L EFA  ++  N    I   D         Y +NP+N +   ++F   WK    L+ +   +++  +L + ++  + R P+ D  D+ GAI A+ R+Q TY++  +  V GK+    +  KL ADDCF +G  AY  E +  A +W +E+    +I K +   T   R  +L+YLS+   + G  +AALN + ELL+    +  +R+ +    K   +   ++S   +  N++     +++  + Y+ LCRGE PI+V   +    K+  C Y+        + P KVE     PR+VI   L+ D E   IK +ASP LNRATV N  TG+LE+A YR+SKSAWL + LDE  + +NKRI   TGL+++ AE LQ+ NYG+GG Y  H DHG+     A +   GNRIATLL Y++DV  GGATVF + G  + P K
Sbjct:   24 VFDSLSHLKDLVQLETELGDRLKTYVEKQHENFETLKEFAALVRESNNLVKIHGTD---------YLNNPVNQFAIIKRFFKGWKQVESLLTE--GDEYTALL-DSLEANKKRFPSDDGNDLMGAIAAIFRIQHTYNITAQTFVNGKLPGCPAASKLTADDCFELGTAAYGSEQYTRAREWLEEA---DRILKEEHQETATSRIEVLEYLSWLQYATGDTKAALNSSLELLRIDPRHKSVRESIEHYSKAVKHGEPELSYPQIKANEQRLNI-EYFVNSDYSKLCRGE-PIKVRHFQVMSAKSYHCWYDNRGDARLLLKPNKVEQVNDDPRVVIFRGLVTDRETARIKQIASPMLNRATVYNIDTGVLEYADYRVSKSAWLEDHLDETIATVNKRIAMVTGLDVQTAEKLQIANYGMGGQYEQHTDHGEPDSPLAND-PLGNRIATLLIYLNDVALGGATVFLKAGVHVPPTK 478

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Medaka
Match: p4ha2 (prolyl 4-hydroxylase subunit alpha 2 [Source:NCBI gene;Acc:101166436])

HSP 1 Score: 350.132 bits (897), Expect = 1.841e-113
Identity = 209/552 (37.86%), Postives = 307/552 (55.62%), Query Frame = 2

Query:   74 FLFSILVAIFNCL--YGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYN-ISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLV-----NDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQ-SPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFS-------------DHY-DGNFYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 1651
            FL  I   + +CL  + E+FT++  ++ +   EK+L + L  Y+  EE +L  +  +A +L     +S +D       E Y ++P+N+Y   ++   +W +   LV     + F++N         +   +   P+ +D  GA  A++RLQ+TY LD++    G +    SN  L  DDCF++G  AY   ++  AV WF+++L      +   +  +++  ILDYLSY +  +G    A+  T  L+   PN     R   N  Y+ + + +++  +N +    S             DH  +   Y ALCRGE       R   L C  ++    P   + P+K E  +  P +V   +++ D+EIE IK +A P+L RATVR+P TG+L  A YR+SKSAWL  + D +  ++N+RI   TGL +E AE LQV NYG+GG Y PHFD  +K   DAF+ +  GNR+AT L YMSDVEAGGATVF + GA +WP+KG+A FW+NL  +GE D  TRHA CPVLVGSKWV NKW HERGQEF+RPC L  +
Sbjct:    3 FLVFISWVLVSCLRTHAEVFTSIGQMTDLLYTEKELVQSLRDYIKAEESKLAAVKSWANKLDALTRVSTSD------PEGYLAHPVNAYKLMKRLNTEWSELESLVLQNPSDGFISN---------MSVHRQYFPDEEDQTGAAKALMRLQDTYQLDSEAFSKGMLPGVHSNAVLTVDDCFDMGKTAYNDADYYHAVLWFQQALKQLDDGE---EAAVSKADILDYLSYSVYQMGDLPRAIELTRRLVAIDPN---HQRAGGNLRYFEQLLMKQLKESNQDYQPPSEEPIQLGTYTRPKDHLPERETYEALCRGEGLQLTEARRSRLFCRYHDGKRSPRLLLKPIKEEDEWDNPHIVRYLNILSDQEIEKIKELAKPRLARATVRDPKTGVLTTAPYRVSKSAWLEGEDDPVIDRVNQRIQDITGLTVETAELLQVANYGVGGQYEPHFDFSRKDEPDAFKRLGTGNRMATFLNYMSDVEAGGATVFPDFGASIWPRKGTAVFWYNLFRSGEGDYRTRHAACPVLVGSKWVSNKWIHERGQEFRRPCGLTEV 533

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Query:   74 FLFSILVAIFNCL--YGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYN-ISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLV-----NDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQ-SPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFS-------------DHY-DGNFYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFE-IERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 1651
            FL  I   + +CL  + E+FT++  ++ +   EK+L + L  Y+  EE +L  +  +A +L     +S +D       E Y ++P+N+Y   ++   +W +   LV     + F++N         +   +   P+ +D  GA  A++RLQ+TY LD++    G +    SN  L  DDCF++G  AY   ++  AV WF+++L      +   +  +++  ILDYLSY +  +G    A+  T  L+   PN     R   N  Y+ + + +++  +N +    S             DH  +   Y ALCRGE       R   L C  ++    P   + P+K E  +  P +V   +++ D+EIE IK +A P+L RATVR+P TG+L  A YR+SKSAWL  + D +  ++N+RI   TGL +E AE LQV NYG+GG Y PHFD  +K   DAF+ +  GNR+AT L YMSDVEAGGATVF + GA +WP+KG+A FW+NL  +GE D  TRHA CPVLVGSKWV NKW HERGQEF+RPC L  +
Sbjct:    3 FLVFISWVLVSCLRTHAEVFTSIGQMTDLLYTEKELVQSLRDYIKAEESKLAAVKSWANKLDALTRVSTSD------PEGYLAHPVNAYKLMKRLNTEWSELESLVLQNPSDGFISN---------MSVHRQYFPDEEDQTGAAKALMRLQDTYQLDSEAFSKGMLPGVHSNAVLTVDDCFDMGKTAYNDADYYHAVLWFQQALKQLDDGE---EAAVSKADILDYLSYSVYQMGDLPRAIELTRRLVAIDPN---HQRAGGNLRYFEQLLMKQLKESNQDYQPPSEEPIQLGTYTRPKDHLPERETYEALCRGEGLQLTEARRSRLFCRYHDGKRSPRLLLKPIKEEDEWDNPHIVRYLNILSDQEIEKIKELAKPRLARATVRDPKTGVLTTAPYRVSKSAWLEGEDDPVIDRVNQRIQDITGLTVETAELLQVANYGVGGQYEPHFDFSRKDEPDAFKRLGTGNRMATFLNYMSDVEAGGATVFPDFGASIWPRKGTAVFWYNLFRSGEGDYRTRHAACPVLVGSKWVSNKWIHERGQEFRRPCGLTEV 533

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BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Medaka
Match: p4ha1b (prolyl 4-hydroxylase subunit alpha 1 [Source:NCBI gene;Acc:101163841])

HSP 1 Score: 340.502 bits (872), Expect = 1.315e-109
Identity = 202/535 (37.76%), Postives = 296/535 (55.33%), Query Frame = 2

Query:  119 ELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQ-SPNSDIRDRLLKNKNYY---LEK------ISEEIVPNNDENPGFSDHY--------------DGNFYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKL 1642
            + FT++  ++ +   EKDL   L  Y+  EE +L ++  +A  L +   +A     + + E +  +P+N++   ++   +W +   LV     + F   L  +   F    P  +D  GA  A++RLQ+TY+LD   +  G +   +   ++  +DC+ +G  AY + ++     W  ++L   +  +  P   L++ ++LDYLSY +   G  + AL YT +LLQ  P      R   N+ Y+   LEK       +E+     D     +                 +   Y  LCRGE     S R+  L C  Y+   +P + + P+K +  + +P +V   D+I + E++ IK +A P+L RAT+ NP TG+LE A YRISKSAWL    D +  KIN+RI   TGL ++ AE+LQV NYG+GG Y PHFD G+K   DAF E+  GNRIAT LFYMSDV AGGATVF +VGA + P+KG+A FW+NL A+GE D  TRHA CPVLVG+KWV NKW HERGQE++RPC L
Sbjct:   22 DFFTSIGQMTDLLYTEKDLVTSLKDYIRAEENKLEQVKRWADRLDSLTSTA-----TQDPEGFLGHPVNAFKLMKRLNTEWGNLESLVLSDTTDGFISNLTIQRQYF----PTEEDQTGAAKALLRLQDTYNLDANTISTGDLPGVKHKNRMTVEDCYELGKVAYAEADYYHTELWMAQALRQLEEGEESP---LDKVTVLDYLSYAIYQQGDLKRALEYTKKLLQLDPE---HQRANGNQKYFEFQLEKQEKQDETAEKETQQQDREKRDTTQKKKKKQSQKSLSLIPERKKYEMLCRGEGVRMTSRRQSRLFCRYYDNKHNPRFVLAPVKQQDEWDRPYIVRYIDIISEAEMDKIKQLAKPRLRRATISNPVTGVLETAPYRISKSAWLTAYEDPVVEKINQRIEDLTGLEMDTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPDVGASVGPQKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEWRRPCGL 541

[Close]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Medaka
Match: p4ha1b (prolyl 4-hydroxylase subunit alpha 1 [Source:NCBI gene;Acc:101163841])

HSP 1 Score: 335.495 bits (859), Expect = 5.999e-108
Identity = 200/527 (37.95%), Postives = 291/527 (55.22%), Query Frame = 2

Query:  143 LSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQ-SPNSDIRDRLLKNKNYY---LEK------ISEEIVPNNDENPGFSDHY--------------DGNFYTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKL 1642
            ++ +   EKDL   L  Y+  EE +L ++  +A  L +   +A     + + E +  +P+N++   ++   +W +   LV     + F   L  +   F    P  +D  GA  A++RLQ+TY+LD   +  G +   +   ++  +DC+ +G  AY + ++     W  ++L   +  +  P   L++ ++LDYLSY +   G  + AL YT +LLQ  P      R   N+ Y+   LEK       +E+     D     +                 +   Y  LCRGE     S R+  L C  Y+   +P + + P+K +  + +P +V   D+I + E++ IK +A P+L RAT+ NP TG+LE A YRISKSAWL    D +  KIN+RI   TGL ++ AE+LQV NYG+GG Y PHFD G+K   DAF E+  GNRIAT LFYMSDV AGGATVF +VGA + P+KG+A FW+NL A+GE D  TRHA CPVLVG+KWV NKW HERGQE++RPC L
Sbjct:    1 MTDLLYTEKDLVTSLKDYIRAEENKLEQVKRWADRLDSLTSTA-----TQDPEGFLGHPVNAFKLMKRLNTEWGNLESLVLSDTTDGFISNLTIQRQYF----PTEEDQTGAAKALLRLQDTYNLDANTISTGDLPGVKHKNRMTVEDCYELGKVAYAEADYYHTELWMAQALRQLEEGEESP---LDKVTVLDYLSYAIYQQGDLKRALEYTKKLLQLDPE---HQRANGNQKYFEFQLEKQEKQDETAEKETQQQDREKRDTTQKKKKKQSQKSLSLIPERKKYEMLCRGEGVRMTSRRQSRLFCRYYDNKHNPRFVLAPVKQQDEWDRPYIVRYIDIISEAEMDKIKQLAKPRLRRATISNPVTGVLETAPYRISKSAWLTAYEDPVVEKINQRIEDLTGLEMDTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPDVGASVGPQKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEWRRPCGL 512

[Close]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Medaka
Match: ENSORLT00000018692.2 (prolyl 4-hydroxylase subunit alpha-1 [Source:NCBI gene;Acc:101172363])

HSP 1 Score: 335.88 bits (860), Expect = 1.121e-107
Identity = 194/515 (37.67%), Postives = 298/515 (57.86%), Query Frame = 2

Query:  119 ELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQ-SPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFSDHYDGNF------YTALCRGESPIEVSEREKNLKC--YNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAF-EIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRP 1633
            +LFT++  ++ +   EKDL   L  Y+  EE++L  + ++A+ L   + ++++     + E +  +P+N++   ++   +W +  +LV   +++ F   L  +   F    PN +D  GA  A++RLQ+TY L+T  +  G++      + L ADDC+++G  AY + ++     W  ++L   ++ + +   T++  ++LDYLSY +   G  +AAL++T  LL+  P     +  LK   Y L K  + +  N  E        D  +      Y  LCRG+  +    R   L C  +N   HP Y IGP+K E  +  P +V  HD+  ++E+E +K +A P+L RATV +P TG L  A YR+SKSAWL +    I  +IN+RI   TGL++  AEDLQV NYG+GG Y PHFD G+K   DAF E+  GNRIAT L YMSDV+AGG TVFT++GA +WPKKG+A FW+NL  +GE D  TRHA CPVLVG+KW  + + H +G++ +RP
Sbjct:   35 DLFTSIGQMTDLLIMEKDLLSSLKDYISAEEQKLRRIKQWAERLDVLSAASSE-----DAEGFLGHPVNAFKLVKRLNTEWAELENLVLTDMSDAFIANLTIQRQFF----PNDEDQAGAAKALMRLQDTYQLETSIISSGQL----PGLVLTADDCYDLGKVAYSEADYFHTKLWMTQALR--QLEQGEASSTVDTATVLDYLSYSVYQQGELQAALDFTKRLLELDPTHQRANGNLKYFEYQLSKQKKAVQMNESEEDQKGAQADDEYLLERRKYEQLCRGQGALMTPRRLSRLFCRYFNNHGHPNYLIGPVKQEDEWDSPYIVRYHDVASEKEMETVKELAKPRLRRATVHDPQTGKLTTAQYRVSKSAWLGSHEHPIVDRINQRIEDITGLDVSTAEDLQVANYGVGGQYEPHFDFGRKDEADAFEELGTGNRIATWLLYMSDVQAGGNTVFTDIGAVVWPKKGTAVFWYNLHRSGEGDYRTRHAACPVLVGNKWGESTFLH-KGKQKRRP 533

[Close]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Planmine SMEST
Match: SMESG000005668.1 (SMESG000005668.1)

HSP 1 Score: 1065.06 bits (2753), Expect = 0.000e+0
Identity = 532/532 (100.00%), Postives = 532/532 (100.00%), Query Frame = 2

Query:   56 MDFKRFFLFSILVAIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFSDHYDGNFYTALCRGESPIEVSEREKNLKCYNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 1651
            MDFKRFFLFSILVAIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFSDHYDGNFYTALCRGESPIEVSEREKNLKCYNKIPHPFYKIGPLKVEVAFSKPRLVIIHDLIHDEEIEHIKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI
Sbjct:    1 MDFKRFFLFSILVAIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIRDRLLKNKNYYLEKISEEIVPNNDENPGFSDHYDGNFYTALCRGESPIEVSEREKNLKCYNKIPHPFYKIGPLKVEVAFSKPRLVIIHDLIHDEEIEHIKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI 532

[Close]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Planmine SMEST
Match: SMESG000060999.1 (SMESG000060999.1)

HSP 1 Score: 395.201 bits (1014), Expect = 4.997e-131
Identity = 237/531 (44.63%), Postives = 324/531 (61.02%), Query Frame = 2

Query:  116 GELFTALVDLSKVFKAEKDLSELLHQYVLNEEKRLNELVEFAKELKTYNISANDFSDSMEI-------EKYFSNPINSYLFARKFVHDWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQETYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKESLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPNSDIR-----------DRLLKNKNYYLE-KISEEIVPNNDENPGFSDHYDGN---FYTALCRGESPIEVSEREKNLKCYNKIPHPFYKIGPLKVEVAFSKPRLVXXXXXXXXXXXXXXKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKRITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPCKL 1642
            GE+FTALVDL++ F ++  L               N L+EFA E K +  S   F+ S+ +       E Y +NP+ +YL  ++ +  WK++  ++    +  F  I    I +  + LPN DD+ G+IDA++RLQ+TY + T  +  G I   + +  L +  CF IG+ +++K+ F   V+W  E+   ++IN+      +    +LDYLS+        R AL  T E  +    ++R            + ++N N + +  I +        N   S H  GN    Y ALCRGES I+ +    +LKC   +PH ++ +GP+K E  F KPR+VI HDLI+D EIE IK ++  KL RATV+N  TG LEFA+YRISKSAWL  D++E+T +IN RI   TG+N+E AE+LQVVNYGIGGHY PHFD  +K   ++FE E GNR+ATLLFYMSDVEAGGATVFT++GAK+WPKKG+AAFW+NL  +GE D  TRHA CPVL+GSKWVMNKWFHERGQEF RPC L
Sbjct:   15 GEVFTALVDLTQSFNSKLQLG--------------NNLLEFANEAKAHIQSLKAFTKSIHVTPENQNPETYINNPLKAYLLIQRLIRYWKEEFPILIS-TDENFDSI-ANRIQQLLNYLPNKDDLKGSIDALVRLQDTYKIKTHKIANGIITRNEKSNSLTSQQCFEIGLRSFEKDYFYF-VEWASEAY--YRINENVKSEKI---KLLDYLSFGFFKQNNLRQALALTKEWRKIDPLNVRASENEIYFTQEQQNIRNSNSFFKGDIGDLFTDLAAINVRPSTHDRGNEFRTYEALCRGESTIK-NPNLHSLKCRYYVPHYYFLLGPIKEETLFHKPRIVIYHDLINDNEIEGIKRLSINKLRRATVQNSITGKLEFANYRISKSAWLRTDVNELTERINLRIQLVTGINLETAEELQVVNYGIGGHYEPHFDFARKSEINSFESEIGNRLATLLFYMSDVEAGGATVFTKIGAKIWPKKGAAAFWWNLLPSGEGDLSTRHAACPVLLGSKWVMNKWFHERGQEFTRPCAL 522

[Close]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Planmine SMEST
Match: SMESG000006029.1 (SMESG000006029.1)

HSP 1 Score: 94.3597 bits (233), Expect = 4.577e-20
Identity = 51/151 (33.77%), Postives = 78/151 (51.66%), Query Frame = 2

Query: 1229 EITSKINKRITASTGLN---------IEMAEDLQVVNYGIGGH------YSPHFDHGKKRPQDAFEIERGNRIATLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHAGCPVLVGSKWVMNKWFHERGQEFQRPC 1636
            ++   ++++I+  TGL          I  +   +V+NYGIGG+      Y    D  KK+    F    G+R+AT  ++++D   GG  VF +V   L  ++G+   WFNL  NG  + ++ H  CPV  GSKWV+ K+ HE G  F R C
Sbjct:  415 DVMKSLSRQISHQTGLETNNHKYNTRISSSGPFKVINYGIGGYEELEVDYLAKVDEEKKKDVSVFG---GDRLATWHYHLTDKIEGGRIVFPKVKMSLLLEQGTGLLWFNLLKNGTVNPLSEHMECPVAYGSKWVVKKFIHENGNMFTRKC 562

The following BLAST results are available for this feature:

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Human
BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Celegans
BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Fly
BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Zebrafish
BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Xenopus
BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Mouse
BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. UniProt/SwissProt
BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. TrEMBL
BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Cavefish
BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Sea Lamprey
BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Yeast
BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Nematostella
BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Medaka
BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Planmine SMEST

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
P4HA2	1.043e-115	38.97	prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC ...	[more]
P4HA2	1.043e-115	38.97	prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC ...	[more]
P4HA2	1.043e-115	38.97	prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC ...	[more]
P4HA2	2.970e-115	39.23	prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC ...	[more]
P4HA2	2.970e-115	39.23	prolyl 4-hydroxylase subunit alpha 2 [Source:HGNC ...	[more]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
phy-2	3.535e-122	42.18	Prolyl 4-hydroxylase subunit alpha-2 [Source:UniP...	[more]
dpy-18	6.031e-111	38.96	Prolyl 4-hydroxylase subunit alpha-1 [Source:UniP...	[more]
phy-4	1.507e-25	29.57	Proline HYdroxylase [Source:UniProtKB/TrEMBL;Acc:...	[more]
Y43F8B.19	1.458e-21	39.83	pep chromosome:WBcel235:V:19510780:19512164:-1 gen...	[more]
phy-3	8.320e-21	36.09	Proline HYdroxylase [Source:UniProtKB/TrEMBL;Acc:...	[more]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PH4alphaEFB	3.738e-123	40.15	gene:FBgn0039776 transcript:FBtr0085650	[more]
PH4alphaPV	3.327e-80	33.01	gene:FBgn0051015 transcript:FBtr0085670	[more]
PH4alphaSG1	1.064e-77	32.66	gene:FBgn0051014 transcript:FBtr0085686	[more]
PH4alphaMP	1.026e-72	29.89	gene:FBgn0026190 transcript:FBtr0085689	[more]
CG9698	5.390e-71	31.56	gene:FBgn0039784 transcript:FBtr0085657	[more]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
p4ha1a	3.548e-116	39.92	prolyl 4-hydroxylase, alpha polypeptide I a [Sourc...	[more]
p4ha1a	3.548e-116	39.92	prolyl 4-hydroxylase, alpha polypeptide I a [Sourc...	[more]
p4ha1a	1.671e-114	39.55	prolyl 4-hydroxylase, alpha polypeptide I a [Sourc...	[more]
p4ha1a	1.671e-114	39.55	prolyl 4-hydroxylase, alpha polypeptide I a [Sourc...	[more]
p4ha1b	5.939e-114	39.06	prolyl 4-hydroxylase, alpha polypeptide I b [Sourc...	[more]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
notch3	2.513e-118	38.98	notch 3 [Source:Xenbase;Acc:XB-GENE-6450008]	[more]
notch3	9.359e-117	38.87	notch 3 [Source:Xenbase;Acc:XB-GENE-6450008]	[more]
mlxip	1.327e-115	40.41	MLX interacting protein [Source:Xenbase;Acc:XB-GEN...	[more]
mlxip	2.041e-114	39.78	MLX interacting protein [Source:Xenbase;Acc:XB-GEN...	[more]
notch3	1.028e-113	38.52	notch 3 [Source:Xenbase;Acc:XB-GENE-6450008]	[more]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
P4ha2	4.213e-116	38.73	procollagen-proline, 2-oxoglutarate 4-dioxygenase ...	[more]
P4ha2	2.527e-114	38.62	procollagen-proline, 2-oxoglutarate 4-dioxygenase ...	[more]
P4ha2	2.527e-114	38.62	procollagen-proline, 2-oxoglutarate 4-dioxygenase ...	[more]
P4ha1	4.373e-109	39.58	procollagen-proline, 2-oxoglutarate 4-dioxygenase ...	[more]
P4ha1	1.041e-108	39.39	procollagen-proline, 2-oxoglutarate 4-dioxygenase ...	[more]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q20065\|P4HA2_CAEEL	4.497e-121	42.18	Prolyl 4-hydroxylase subunit alpha-2 OS=Caenorhabd...	[more]
sp\|O15460\|P4HA2_HUMAN	5.010e-115	38.97	Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapie...	[more]
sp\|Q60716\|P4HA2_MOUSE	1.024e-114	38.55	Prolyl 4-hydroxylase subunit alpha-2 OS=Mus muscul...	[more]
sp\|Q5ZLK5\|P4HA2_CHICK	5.912e-112	40.30	Prolyl 4-hydroxylase subunit alpha-2 OS=Gallus gal...	[more]
sp\|Q10576\|P4HA1_CAEEL	7.671e-110	38.96	Prolyl 4-hydroxylase subunit alpha-1 OS=Caenorhabd...	[more]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
G4VTC9	7.948e-143	43.37	Putative prolyl 4-hydroxylase alpha subunit 1 OS=S...	[more]
A0A1C9TA56	2.538e-132	42.99	Prolyl 4-hydroxylase subunit alpha-1-like protein ...	[more]
A0A0P5JIY1	4.983e-127	43.53	Prolyl 4-hydroxylase subunit alpha-1 OS=Daphnia ma...	[more]
A0A0P5NSW2	2.240e-126	43.53	Prolyl 4-hydroxylase subunit alpha-1 OS=Daphnia ma...	[more]
A0A430Q6X2	2.394e-126	38.66	Prolyl 4-hydroxylase OS=Schistosoma bovis OX=6184 ...	[more]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
p4ha1b	4.797e-112	38.56	prolyl 4-hydroxylase subunit alpha-1-like [Source:...	[more]
p4ha1a	5.913e-112	38.35	prolyl 4-hydroxylase subunit alpha 1 [Source:NCBI ...	[more]
p4ha2	4.067e-110	36.40	prolyl 4-hydroxylase subunit alpha 2 [Source:NCBI ...	[more]
p4ha1b	6.841e-110	38.19	prolyl 4-hydroxylase subunit alpha-1-like [Source:...	[more]
p4ha2	2.102e-100	33.87	prolyl 4-hydroxylase subunit alpha 2 [Source:NCBI ...	[more]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3


Match Name	E-value	Identity	Description
p4ha1b	9.157e-28	26.72	prolyl 4-hydroxylase, alpha polypeptide I b [Sourc...	[more]
p4ha1b	1.852e-20	29.33	prolyl 4-hydroxylase, alpha polypeptide I b [Sourc...	[more]
ENSPMAT00000002062.1	1.150e-7	25.00	pep scaffold:Pmarinus_7.0:GL478223:560729:563134:-...	[more]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO30487	2.182e-108	39.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36261	6.058e-106	35.83	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46235	5.829e-83	33.97	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36263	7.150e-81	33.40	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36288	5.665e-70	35.10	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
p4ha2	1.841e-113	37.86	prolyl 4-hydroxylase subunit alpha 2 [Source:NCBI ...	[more]
p4ha2	1.841e-113	37.86	prolyl 4-hydroxylase subunit alpha 2 [Source:NCBI ...	[more]
p4ha1b	1.315e-109	37.76	prolyl 4-hydroxylase subunit alpha 1 [Source:NCBI ...	[more]
p4ha1b	5.999e-108	37.95	prolyl 4-hydroxylase subunit alpha 1 [Source:NCBI ...	[more]
ENSORLT00000018692.2	1.121e-107	37.67	prolyl 4-hydroxylase subunit alpha-1 [Source:NCBI ...	[more]

BLAST of Prolyl 4-hydroxylase subunit alpha-1-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3


Match Name	E-value	Identity	Description
SMESG000005668.1	0.000e+0	100.00	SMESG000005668.1	[more]
SMESG000060999.1	4.997e-131	44.63	SMESG000060999.1	[more]
SMESG000006029.1	4.577e-20	33.77	SMESG000006029.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30010666 ID=SMED30010666|Name=Prolyl 4-hydroxylase subunit alpha-1-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1835bp
GGGAAAGTGATTTATCAATCGATAAGCATATCACGTACTTTCTTATTCAA
TTTGGATGGATTTTAAACGATTTTTTTTATTTTCAATTCTAGTTGCAATT
TTCAATTGTCTGTATGGTGAACTGTTTACAGCGTTAGTCGATCTTTCAAA
GGTTTTTAAAGCAGAAAAAGACCTTAGTGAATTGTTGCATCAATATGTTT
TAAACGAAGAAAAACGACTCAATGAACTTGTTGAATTTGCAAAAGAACTC
AAAACTTACAACATCTCAGCAAATGATTTCAGTGATTCAATGGAAATTGA
AAAATACTTTTCCAATCCAATCAATTCTTATTTATTCGCAAGAAAATTTG
TTCACGATTGGAAAGATAAACTGGATTTGGTGAATGATTTCGTAAATAAC
AAATTCAGAAAAATCCTACAAGAAGAAATTGACAAATTCCAAGATCGCCT
TCCGAATACTGATGATATTGACGGAGCAATAGACGCAATGATTAGATTAC
AGGAAACATATCATTTAGACACGAAAGACCTTGTTGTTGGGAAAATTCAG
AATTTTCAATCAAATGTTAAGTTAAACGCCGATGATTGTTTCAACATTGG
AGTACATGCATACAAAAAGGAAAATTTTCCCATAGCTGTAAAATGGTTCA
AAGAATCATTAAATTTATTTAAAATAAATAAAGTTGACCCTGATGGAACT
CTAAATGAAAGATCAATTCTTGATTATCTTTCCTATTGTCTAGGATCAGT
TGGAATGTATAGAGCGGCTTTGAATTACACAAACGAATTACTCCAATCTC
CAAACAGTGATATTCGAGATCGGTTACTAAAAAATAAAAATTACTATTTG
GAAAAAATATCTGAAGAAATAGTTCCTAATAATGATGAAAATCCTGGCTT
TTCCGATCATTATGACGGGAATTTTTACACCGCTTTGTGTCGAGGTGAAT
CCCCAATTGAGGTGTCTGAAAGGGAAAAAAATCTGAAATGTTACAACAAA
ATACCTCATCCGTTTTACAAAATCGGACCATTGAAAGTTGAAGTAGCATT
TAGCAAACCGAGATTGGTAATAATTCATGATTTAATACATGATGAAGAAA
TTGAACATATTAAATCTGTCGCGTCACCAAAACTGAACAGAGCCACTGTA
AGGAATCCATCAACTGGAATTCTAGAATTTGCAAGCTATCGAATAAGTAA
AAGTGCTTGGTTGCCAAATGATTTGGACGAAATAACTTCAAAAATTAACA
AAAGAATAACTGCTTCGACAGGACTTAATATTGAGATGGCGGAAGATTTG
CAAGTGGTTAACTACGGAATAGGGGGTCATTATTCACCACATTTTGACCA
TGGAAAAAAACGTCCTCAAGATGCTTTTGAAATCGAGCGTGGCAATAGAA
TAGCAACTCTATTATTTTATATGTCTGATGTCGAAGCTGGTGGAGCAACA
GTATTCACGGAGGTAGGTGCTAAATTGTGGCCAAAAAAAGGCAGTGCTGC
TTTCTGGTTTAATCTTAAAGCAAATGGGGAAAGTGACGATATGACAAGAC
ATGCTGGTTGTCCAGTTTTAGTGGGTTCGAAATGGGTTATGAATAAATGG
TTTCATGAAAGAGGCCAAGAATTCCAACGACCTTGCAAGTTGAAAAATAT
ATGAATCATTTGCTCTTTTCTAATGAAAGTTTCTCAAAATATATTTTTAC
TACTGAAGTTTTTATTAAAATTAAAAAATAACACTAGAATTACCAGCATT
TGATGTAAACATATTTTTACTAGCTCCGTCACTTTAACGGGTTAAAAAAC
ACTTATTCTGGGCAACAAAAGTTTATTTAAGTTAT

protein sequence of SMED30010666-orf-1

>SMED30010666-orf-1 ID=SMED30010666-orf-1|Name=SMED30010666-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=533bp
MDFKRFFLFSILVAIFNCLYGELFTALVDLSKVFKAEKDLSELLHQYVLN
EEKRLNELVEFAKELKTYNISANDFSDSMEIEKYFSNPINSYLFARKFVH
DWKDKLDLVNDFVNNKFRKILQEEIDKFQDRLPNTDDIDGAIDAMIRLQE
TYHLDTKDLVVGKIQNFQSNVKLNADDCFNIGVHAYKKENFPIAVKWFKE
SLNLFKINKVDPDGTLNERSILDYLSYCLGSVGMYRAALNYTNELLQSPN
SDIRDRLLKNKNYYLEKISEEIVPNNDENPGFSDHYDGNFYTALCRGESP
IEVSEREKNLKCYNKIPHPFYKIGPLKVEVAFSKPRLVIIHDLIHDEEIE
HIKSVASPKLNRATVRNPSTGILEFASYRISKSAWLPNDLDEITSKINKR
ITASTGLNIEMAEDLQVVNYGIGGHYSPHFDHGKKRPQDAFEIERGNRIA
TLLFYMSDVEAGGATVFTEVGAKLWPKKGSAAFWFNLKANGESDDMTRHA
GCPVLVGSKWVMNKWFHERGQEFQRPCKLKNI*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000101	muscle cell

Vocabulary: **INTERPRO**
Term	Definition
IPR006620	Pro_4_hyd_alph
IPR005123	Oxoglu/Fe-dep_dioxygenase
IPR011990	TPR-like_helical_dom_sf
IPR013547	Pro_4_hyd_alph_N

Vocabulary: **biological process**
Term	Definition
GO:0055114	oxidation-reduction process
GO:0019511	peptidyl-proline hydroxylation

Vocabulary: **molecular function**
Term	Definition
GO:0031418	L-ascorbic acid binding
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0005506	iron ion binding
GO:0016491	oxidoreductase activity
GO:0005515	protein binding
GO:0004656	procollagen-proline 4-dioxygenase activity
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

Vocabulary: **cellular component**
Term	Definition
GO:0005783	endoplasmic reticulum

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006620	Prolyl 4-hydroxylase, alpha subunit	SMART	SM00702	p4hc	coord: 335..517 e-value: 5.7E-63 score: 225.2
None	No IPR available	GENE3D	G3DSA:2.60.120.620		coord: 328..517 e-value: 1.7E-60 score: 206.4
None	No IPR available	PANTHER	PTHR10869	PROLYL 4-HYDROXYLASE ALPHA SUBUNIT	coord: 26..528
None	No IPR available	PANTHER	PTHR10869:SF154	PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2	coord: 26..528
None	No IPR available	TMHMM	TMhelix		coord: 7..29
IPR011990	Tetratricopeptide-like helical domain superfamily	GENE3D	G3DSA:1.25.40.10		coord: 135..268 e-value: 6.9E-33 score: 115.4
IPR011990	Tetratricopeptide-like helical domain superfamily	SUPERFAMILY	SSF48452	TPR-like	coord: 173..251
IPR005123	Oxoglutarate/iron-dependent dioxygenase	PFAM	PF13640	2OG-FeII_Oxy_3	coord: 415..517 e-value: 4.6E-16 score: 59.5
IPR005123	Oxoglutarate/iron-dependent dioxygenase	PROSITE	PS51471	FE2OG_OXY	coord: 411..518 score: 11.888
IPR013547	Prolyl 4-hydroxylase alpha-subunit, N-terminal	PFAM	PF08336	P4Ha_N	coord: 27..165 e-value: 2.4E-28 score: 98.8

Main menu

Prolyl 4-hydroxylase subunit alpha-1-like protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 11

Owlery

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