Potassium voltage-gated channel subfamily A member 2

Overview


Name	Potassium voltage-gated channel subfamily A member 2
Smed ID	SMED30010596
Length (bp)	485

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Embryonic Expression

Davies et. al., 2017

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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30010596

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30010596	SMESG000014206.1 SMESG000014198.1	dd_Smed_v6_56222_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
secretory cell	SMED30010596	SMESG000014206.1 SMESG000014198.1	KF134118	smed_ncbi_20200123	PMID:23903188 Currie et al., 2013
ventral region of the whole animal	SMED30010596	SMESG000014206.1 SMESG000014198.1	KF134118	smed_ncbi_20200123	PMID:23903188 Currie et al., 2013
parapharyngeal region	SMED30010596	SMESG000014206.1 SMESG000014198.1	KF134118	smed_ncbi_20200123	PMID:23903188 Currie et al., 2013
serotonergic neuron	SMED30010596	SMESG000014206.1 SMESG000014198.1	KF134118	smed_ncbi_20200123	PMID:23903188 Currie et al., 2013

Note: Hover over icons to view figure legend

Homology

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221])

HSP 1 Score: 143.665 bits (361), Expect = 3.515e-40
Identity = 68/170 (40.00%), Postives = 107/170 (62.94%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKE-------------------THCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF EE++F+Q+ +E + K++ +EG + EE   LP+  +Q+++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP F++                   T      A +F D FF++ET C  WFS E +VR   CPSK    +++ N +DI+AI+PY++TL
Sbjct:  174 NVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITL 343

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Match: KCNA2 (potassium voltage-gated channel subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:6220])

HSP 1 Score: 138.272 bits (347), Expect = 1.233e-39
Identity = 68/168 (40.48%), Postives = 109/168 (64.88%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFK-ETHCVDGSA----------------PNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF EE++F+++ +E +  ++ +EG++ EE   LP+ ++Q+++W+LFEYPE+S  A  I ++S++  LISI+ FC+ETLP+F+ E   + GS                  +F D FF++ET C  WFS EF+VR   CPSK     ++ N +DI+AI+PY++TL
Sbjct:  103 NVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITL 270

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Match: KCNA1 (potassium voltage-gated channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:6218])

HSP 1 Score: 140.198 bits (352), Expect = 1.388e-39
Identity = 69/163 (42.33%), Postives = 109/163 (66.87%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKE-------THCVDGS-----APNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP D+F EE+KF+++ +E + K++ +EG + EE   LP+ +YQ+++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP  K+        H +D +     +  F D FF++ET C  WFS E +VR   CPSK    K++ N +DI+AI+PY++TL
Sbjct:   53 NVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTVHRIDNTTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITL 215

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Match: KCNA4 (potassium voltage-gated channel subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:6222])

HSP 1 Score: 142.124 bits (357), Expect = 1.815e-39
Identity = 72/174 (41.38%), Postives = 113/174 (64.94%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV--EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCV--------------DGSAPN--------FLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF EE+KF+Q+ +E ++K++ +EG V  EE   LP+ ++++++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP F++   +              D SAP+        F D FF++ET C  WFS EF+VR   CPS+    K++ N +DI++ILPY++TL
Sbjct:  246 NVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITL 419

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Match: KCNA1 (potassium voltage-gated channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:6218])

HSP 1 Score: 139.813 bits (351), Expect = 3.049e-39
Identity = 69/163 (42.33%), Postives = 109/163 (66.87%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKE-------THCVDGS-----APNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP D+F EE+KF+++ +E + K++ +EG + EE   LP+ +YQ+++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP  K+        H +D +     +  F D FF++ET C  WFS E +VR   CPSK    K++ N +DI+AI+PY++TL
Sbjct:  107 NVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTVHRIDNTTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITL 269

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0])

HSP 1 Score: 111.309 bits (277), Expect = 4.873e-29
Identity = 59/159 (37.11%), Postives = 92/159 (57.86%), Query Frame = 2

Query:    8 VPDDIFLEELKFFQIEKEVVMKYKLEEGHVE-ETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSA-PNFLDS--------FFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            VP DIFL+E++FFQ+  +++ ++ + EG+ + +  ++P  K Q+K+W L EYP++SL A  I  IS+    +SII FC ET+P   E   ++ SA    LD         FF IE  C  WF++E I+R + CP K      + N +D +AI P++V  
Sbjct:  204 VPIDIFLKEMRFFQMGDDLLEEFWIAEGYEKPKEVMMPNNKTQRKIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFVNF 362

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0])

HSP 1 Score: 110.923 bits (276), Expect = 6.698e-29
Identity = 59/159 (37.11%), Postives = 92/159 (57.86%), Query Frame = 2

Query:    8 VPDDIFLEELKFFQIEKEVVMKYKLEEGHVE-ETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSA-PNFLDS--------FFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            VP DIFL+E++FFQ+  +++ ++ + EG+ + +  ++P  K Q+K+W L EYP++SL A  I  IS+    +SII FC ET+P   E   ++ SA    LD         FF IE  C  WF++E I+R + CP K      + N +D +AI P++V  
Sbjct:  216 VPIDIFLKEMRFFQMGDDLLEEFWIAEGYEKPKEVMMPNNKTQRKIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFVNF 374

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0])

HSP 1 Score: 109.768 bits (273), Expect = 1.619e-28
Identity = 59/159 (37.11%), Postives = 92/159 (57.86%), Query Frame = 2

Query:    8 VPDDIFLEELKFFQIEKEVVMKYKLEEGHVE-ETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSA-PNFLDS--------FFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            VP DIFL+E++FFQ+  +++ ++ + EG+ + +  ++P  K Q+K+W L EYP++SL A  I  IS+    +SII FC ET+P   E   ++ SA    LD         FF IE  C  WF++E I+R + CP K      + N +D +AI P++V  
Sbjct:  181 VPIDIFLKEMRFFQMGDDLLEEFWIAEGYEKPKEVMMPNNKTQRKIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFVNF 339

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0])

HSP 1 Score: 109.768 bits (273), Expect = 1.619e-28
Identity = 59/159 (37.11%), Postives = 92/159 (57.86%), Query Frame = 2

Query:    8 VPDDIFLEELKFFQIEKEVVMKYKLEEGHVE-ETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSA-PNFLDS--------FFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            VP DIFL+E++FFQ+  +++ ++ + EG+ + +  ++P  K Q+K+W L EYP++SL A  I  IS+    +SII FC ET+P   E   ++ SA    LD         FF IE  C  WF++E I+R + CP K      + N +D +AI P++V  
Sbjct:  181 VPIDIFLKEMRFFQMGDDLLEEFWIAEGYEKPKEVMMPNNKTQRKIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFVNF 339

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0])

HSP 1 Score: 106.301 bits (264), Expect = 1.801e-27
Identity = 59/158 (37.34%), Postives = 92/158 (58.23%), Query Frame = 2

Query:    8 VPDDIFLEELKFFQIEKEVVMKYKLEEGHVE-ETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSA-PNFLDS--------FFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVT 451
            VP DIFL+E++FFQ+  +++ ++ + EG+ + +  ++P  K Q+K+W L EYP++SL A  I  IS+    +SII FC ET+P   E   ++ SA    LD         FF IE  C  WF++E I+R + CP K      + N +D +AI P++V 
Sbjct:  115 VPIDIFLKEMRFFQMGDDLLEEFWIAEGYEKPKEVMMPNNKTQRKIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFVN 272

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Match: Sh (gene:FBgn0003380 transcript:FBtr0308199)

HSP 1 Score: 140.969 bits (354), Expect = 1.746e-41
Identity = 69/165 (41.82%), Postives = 105/165 (63.64%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKE----------THCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVL 466
            +VP D+F EE+KF+++  + + K++ +EG + EE   LP  + Q+K+W+LFEYPE+S  A  + +IS+   L+SI++FC+ETLP FK           T   +   P+  D FFLIET C  WF+ E  VR + CP+K    +D+ N +DIIAI+PY++TL  V+
Sbjct:  115 NVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVV 279

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Match: Sh (gene:FBgn0003380 transcript:FBtr0089659)

HSP 1 Score: 140.969 bits (354), Expect = 2.128e-41
Identity = 69/165 (41.82%), Postives = 105/165 (63.64%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKE----------THCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVL 466
            +VP D+F EE+KF+++  + + K++ +EG + EE   LP  + Q+K+W+LFEYPE+S  A  + +IS+   L+SI++FC+ETLP FK           T   +   P+  D FFLIET C  WF+ E  VR + CP+K    +D+ N +DIIAI+PY++TL  V+
Sbjct:  122 NVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVV 286

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Match: Sh (gene:FBgn0003380 transcript:FBtr0301955)

HSP 1 Score: 140.969 bits (354), Expect = 2.128e-41
Identity = 69/165 (41.82%), Postives = 105/165 (63.64%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKE----------THCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVL 466
            +VP D+F EE+KF+++  + + K++ +EG + EE   LP  + Q+K+W+LFEYPE+S  A  + +IS+   L+SI++FC+ETLP FK           T   +   P+  D FFLIET C  WF+ E  VR + CP+K    +D+ N +DIIAI+PY++TL  V+
Sbjct:  122 NVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVV 286

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Match: Sh (gene:FBgn0003380 transcript:FBtr0332299)

HSP 1 Score: 140.584 bits (353), Expect = 5.028e-41
Identity = 69/165 (41.82%), Postives = 105/165 (63.64%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKE----------THCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVL 466
            +VP D+F EE+KF+++  + + K++ +EG + EE   LP  + Q+K+W+LFEYPE+S  A  + +IS+   L+SI++FC+ETLP FK           T   +   P+  D FFLIET C  WF+ E  VR + CP+K    +D+ N +DIIAI+PY++TL  V+
Sbjct:  155 NVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVV 319

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Match: Sh (gene:FBgn0003380 transcript:FBtr0089663)

HSP 1 Score: 140.969 bits (354), Expect = 6.352e-41
Identity = 69/165 (41.82%), Postives = 105/165 (63.64%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKE----------THCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVL 466
            +VP D+F EE+KF+++  + + K++ +EG + EE   LP  + Q+K+W+LFEYPE+S  A  + +IS+   L+SI++FC+ETLP FK           T   +   P+  D FFLIET C  WF+ E  VR + CP+K    +D+ N +DIIAI+PY++TL  V+
Sbjct:  167 NVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVV 331

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Zebrafish
Match: kcna1b (potassium voltage-gated channel, shaker-related subfamily, member 1b [Source:ZFIN;Acc:ZDB-GENE-140515-1])

HSP 1 Score: 141.354 bits (355), Expect = 5.180e-40
Identity = 70/161 (43.48%), Postives = 109/161 (67.70%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKET-----HCVDGSA----PNFL-DSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP D+F EE+KF+++ +E + K++ +EG + EE   LP  ++Q+++W+LFE+PE+S  A  I ++S++  LISI++FC+ETLP  KE        +  S     PN L D FF++ET C  WFS E IVR   CPSK A  K++ NT+D+++I+PY++TL
Sbjct:  102 NVPLDMFSEEIKFYELGEEAMEKFREDEGFIREEERPLPDNEFQRQIWLLFEHPESSGPARGIAIVSVMVILISIVIFCLETLPELKEDPQGRLQVIGNSTFYYKPNILTDPFFVVETLCIIWFSFELIVRFFACPSKPAFFKNMMNTIDVVSIIPYFITL 262

[Close]

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKET-----HCVDGSA----PNFL-DSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP D+F EE+KF+++ +E + K++ +EG + EE   LP  ++Q+++W+LFE+PE+S  A  I ++S++  LISI++FC+ETLP  KE        +  S     PN L D FF++ET C  WFS E IVR   CPSK A  K++ NT+D+++I+PY++TL
Sbjct:  102 NVPLDMFSEEIKFYELGEEAMEKFREDEGFIREEERPLPDNEFQRQIWLLFEHPESSGPARGIAIVSVMVILISIVIFCLETLPELKEDPQGRLQVIGNSTFYYKPNILTDPFFVVETLCIIWFSFELIVRFFACPSKPAFFKNMMNTIDVVSIIPYFITL 262

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Zebrafish
Match: kcna1a (potassium voltage-gated channel, shaker-related subfamily, member 1a [Source:ZFIN;Acc:ZDB-GENE-110408-15])

HSP 1 Score: 138.272 bits (347), Expect = 7.627e-39
Identity = 72/161 (44.72%), Postives = 110/161 (68.32%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETH----CVDGSA-----PNFL-DSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP D+F EE+KF+++  E + K++ +EG + EE   LP+ ++Q+++W+LFE+PE+S  A  I ++S++  LISI++FC+ETLP  KE       + G+      P+ L D FF+IET C  WFS E IVR   CPSK A  K++ NT+DI+AI+PY++TL
Sbjct:  104 NVPLDMFSEEIKFYELGVEAMEKFREDEGFIREEERPLPEKEFQRQIWLLFEHPESSGPARGIAIVSVMVILISIVIFCLETLPELKEDPEGRIKIIGNTTYYYKPSILADPFFIIETLCIIWFSFELIVRFFACPSKAAFFKNMMNTIDIVAIIPYFITL 264

[Close]

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETH----CVDGSA-----PNFL-DSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP D+F EE+KF+++  E + K++ +EG + EE   LP+ ++Q+++W+LFE+PE+S  A  I ++S++  LISI++FC+ETLP  KE       + G+      P+ L D FF+IET C  WFS E IVR   CPSK A  K++ NT+DI+AI+PY++TL
Sbjct:  104 NVPLDMFSEEIKFYELGVEAMEKFREDEGFIREEERPLPEKEFQRQIWLLFEHPESSGPARGIAIVSVMVILISIVIFCLETLPELKEDPEGRIKIIGNTTYYYKPSILADPFFIIETLCIIWFSFELIVRFFACPSKAAFFKNMMNTIDIVAIIPYFITL 264

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Zebrafish
Match: CABZ01113981.1 (pep scaffold:GRCz11:KN150008.1:12653:14179:-1 gene:ENSDARG00000102982.2 transcript:ENSDART00000162692.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CABZ01113981.1)

HSP 1 Score: 137.887 bits (346), Expect = 8.019e-39
Identity = 71/157 (45.22%), Postives = 108/157 (68.79%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSA-----PN-FLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF+EE+KF+++ +EV+  +K +EG + EE   LP+ ++Q+++W+LFEYPE+S  A  I ++S++  LISI     E    F+E   V+G+A     PN F D FF++ET C  WFS E +VR + CPSK A  K++ NT+DI+AI+PY++TL
Sbjct:  104 NVPVDIFMEEIKFYELGEEVIENFKEDEGFIKEEERPLPESEFQRQVWLLFEYPESSGPARGIAIVSVLVILISIFR---EDGKAFEEHPGVNGTAASVKKPNPFTDPFFIVETLCIIWFSFELLVRFLACPSKPAFFKNIMNTIDIVAIIPYFITL 257

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Match: KCNA4 (potassium voltage-gated channel subfamily A member 4 [Source:NCBI gene;Acc:100495646])

HSP 1 Score: 145.591 bits (366), Expect = 1.475e-40
Identity = 73/179 (40.78%), Postives = 110/179 (61.45%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETH----------------------------CVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF EE+KF+++ +E ++KY+ +EG V EE   LP+ ++++++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP F++                                D +A  F D FF++ET C  WFS EF VRL  CPSK    KD+ N +DI++ILPY++TL
Sbjct:  263 NVPFDIFSEEVKFYELGEEALLKYREDEGFVKEEEKQLPENEFKKQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDDKDSLLSPLGMGDDGTGEDGEGGAYNATFLLTDHTA--FNDPFFIVETVCIVWFSFEFAVRLFACPSKPGFFKDIMNIIDIVSILPYFITL 439

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221])

HSP 1 Score: 142.124 bits (357), Expect = 3.229e-40
Identity = 68/163 (41.72%), Postives = 108/163 (66.26%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSA------------PNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF EE++F+++ +E + K++ +EG + EE   LP  ++Q+++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP F++     G+A             +F D FF++ET C  WFS E +VR   CPSK    K++ N +DI+AI+PY++TL
Sbjct:   92 NVPIDIFSEEIRFYELGEEAMEKFREDEGFIREEERPLPPNEFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDDKEYSGTALPPGNGTGPYISSSFTDPFFVVETLCIIWFSFELLVRFFACPSKATFCKNIMNIIDIVAIIPYFITL 254

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Match: KCNA2 (potassium channel, voltage gated shaker related subfamily A, member 3 [Source:NCBI gene;Acc:100496794])

HSP 1 Score: 140.584 bits (353), Expect = 1.734e-39
Identity = 72/168 (42.86%), Postives = 107/168 (63.69%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFK-ETHCVDGSAPN----------------FLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF EE++F+++ +E +  ++ +EG + EE   LP  +YQ+++W+LFEYPE+S  A  I +IS++  LISI+ FC+ETLPVF+ E   + GS  N                F D FF++ET C  WFS EF+VR   CPSK     ++ N +DI+AI+PY++TL
Sbjct:  103 NVPLDIFSEEIRFYELGEEAMEIFREDEGFIKEEERPLPDNEYQKQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPVFRDENEDMHGSGVNYYPYSNSTVRYQKSNTFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITL 270

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Match: fastkd3 (FAST kinase domains 3 [Source:Xenbase;Acc:XB-GENE-5998409])

HSP 1 Score: 136.732 bits (343), Expect = 1.577e-38
Identity = 69/162 (42.59%), Postives = 106/162 (65.43%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPN-----------FLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP D+F+EEL F+Q+   V+ K++ +EG + EE  +LP+ ++ +++W+LFE+P++S  A  I +IS++  LISI++FC+ETLP F++    D S P            F D FF++ET C  WFS E  VR + CPSK A  KD+ N +D +AI+PY+V L
Sbjct:   78 NVPLDVFMEELLFYQLGDNVIRKFREDEGFMKEEERLLPECEFMKQVWLLFEHPDSSSAARIIAIISVMVILISIVIFCLETLPEFRDDR--DLSLPKDPLSGRPQKSPFEDPFFIVETICICWFSFELSVRFIACPSKAAFFKDIMNMIDFVAIIPYFVAL 237

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Match: KCNA1 (potassium channel, voltage gated shaker related subfamily A, member 1 [Source:NCBI gene;Acc:100492822])

HSP 1 Score: 137.502 bits (345), Expect = 1.887e-38
Identity = 67/160 (41.88%), Postives = 105/160 (65.62%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPN---------FLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP D+F EE+KF+++ +E + K++ +EG + EE   LP+ ++Q+++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP  K+         N         F D FF++ET C  WFS E +VR   CPSK    K++ N +DI+AI+PY++TL
Sbjct:  104 NVPLDMFSEEIKFYELGEEAMEKFREDEGFIREEERPLPEKEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVIFCLETLPELKDERIFSRRVNNSTVFYKSNIFTDPFFVVETLCIIWFSFELVVRFFACPSKPEFFKNIMNFIDIVAIIPYFITL 263

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
Match: Kcna3 (potassium voltage-gated channel, shaker-related subfamily, member 3 [Source:MGI Symbol;Acc:MGI:96660])

HSP 1 Score: 141.354 bits (355), Expect = 9.205e-40
Identity = 68/170 (40.00%), Postives = 107/170 (62.94%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKE-------------------THCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF EE++F+Q+ +E + K++ +EG + EE   LP+  +Q+++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP F++                   T      A +F D FF++ET C  WFS E +VR   CPSK    +++ N +DI+AI+PY++TL
Sbjct:  127 NVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASPSQDVFEAANNSTSGAPSGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITL 296

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
Match: Kcna4 (potassium voltage-gated channel, shaker-related subfamily, member 4 [Source:MGI Symbol;Acc:MGI:96661])

HSP 1 Score: 142.51 bits (358), Expect = 1.090e-39
Identity = 72/174 (41.38%), Postives = 113/174 (64.94%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV--EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCV--------------DGSAPN--------FLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF EE+KF+Q+ +E ++K++ +EG V  EE   LP+ ++++++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP F++   +              D SAP+        F D FF++ET C  WFS EF+VR   CPS+    K++ N +DI++ILPY++TL
Sbjct:  247 NVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLIMALSAGGHSRLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITL 420

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
Match: Kcna1 (potassium voltage-gated channel, shaker-related subfamily, member 1 [Source:MGI Symbol;Acc:MGI:96654])

HSP 1 Score: 139.813 bits (351), Expect = 2.885e-39
Identity = 69/163 (42.33%), Postives = 109/163 (66.87%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKET-------HCVDGS-----APNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP D+F EE+KF+++ +E + K++ +EG + EE   LP+ +YQ+++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP  K+        H +D +     +  F D FF++ET C  WFS E +VR   CPSK    K++ N +DI+AI+PY++TL
Sbjct:  107 NVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTIHRIDNTTVIYTSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITL 269

[Close]

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKET-------HCVDGS-----APNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP D+F EE+KF+++ +E + K++ +EG + EE   LP+ +YQ+++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP  K+        H +D +     +  F D FF++ET C  WFS E +VR   CPSK    K++ N +DI+AI+PY++TL
Sbjct:  107 NVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTIHRIDNTTVIYTSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITL 269

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
Match: Kcna2 (potassium voltage-gated channel, shaker-related subfamily, member 2 [Source:MGI Symbol;Acc:MGI:96659])

HSP 1 Score: 137.887 bits (346), Expect = 1.211e-38
Identity = 67/168 (39.88%), Postives = 109/168 (64.88%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKET-----------HCVDGS------APNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF EE++F+++ +E +  ++ +EG++ EE   LP+ ++Q+++W+LFEYPE+S  A  I ++S++  LISI+ FC+ETLP+F++            H    S      + +F D FF++ET C  WFS EF+VR   CPSK     ++ N +DI+AI+PY++TL
Sbjct:  103 NVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGGGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITL 270

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Match: sp|P22001|KCNA3_HUMAN (Potassium voltage-gated channel subfamily A member 3 OS=Homo sapiens OX=9606 GN=KCNA3 PE=1 SV=3)

HSP 1 Score: 143.665 bits (361), Expect = 1.688e-39
Identity = 68/170 (40.00%), Postives = 107/170 (62.94%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKE-------------------THCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF EE++F+Q+ +E + K++ +EG + EE   LP+  +Q+++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP F++                   T      A +F D FF++ET C  WFS E +VR   CPSK    +++ N +DI+AI+PY++TL
Sbjct:  174 NVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITL 343

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Match: sp|P16390|KCNA3_MOUSE (Potassium voltage-gated channel subfamily A member 3 OS=Mus musculus OX=10090 GN=Kcna3 PE=1 SV=3)

HSP 1 Score: 141.354 bits (355), Expect = 6.439e-39
Identity = 68/170 (40.00%), Postives = 107/170 (62.94%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKE-------------------THCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF EE++F+Q+ +E + K++ +EG + EE   LP+  +Q+++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP F++                   T      A +F D FF++ET C  WFS E +VR   CPSK    +++ N +DI+AI+PY++TL
Sbjct:  127 NVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASPSQDVFEAANNSTSGAPSGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITL 296

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Match: sp|P15385|KCNA4_RAT (Potassium voltage-gated channel subfamily A member 4 OS=Rattus norvegicus OX=10116 GN=Kcna4 PE=1 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 7.438e-39
Identity = 72/174 (41.38%), Postives = 113/174 (64.94%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV--EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCV--------------DGSAPN--------FLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF EE+KF+Q+ +E ++K++ +EG V  EE   LP+ ++++++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP F++   +              D SAP+        F D FF++ET C  WFS EF+VR   CPS+    K++ N +DI++ILPY++TL
Sbjct:  248 NVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLIMALSAGGHSRLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITL 421

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Match: sp|Q28527|KCNA4_MUSPF (Potassium voltage-gated channel subfamily A member 4 OS=Mustela putorius furo OX=9669 GN=KCNA4 PE=2 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 7.546e-39
Identity = 72/174 (41.38%), Postives = 113/174 (64.94%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV--EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCV--------------DGSAPN--------FLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF EE+KF+Q+ +E ++K++ +EG V  EE   LP+ ++++++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP F++   +              D SAP+        F D FF++ET C  WFS EF+VR   CPS+    K++ N +DI++ILPY++TL
Sbjct:  247 NVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLIMALSAGGHSGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITL 420

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Match: sp|Q61423|KCNA4_MOUSE (Potassium voltage-gated channel subfamily A member 4 OS=Mus musculus OX=10090 GN=Kcna4 PE=1 SV=2)

HSP 1 Score: 142.51 bits (358), Expect = 7.622e-39
Identity = 72/174 (41.38%), Postives = 113/174 (64.94%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV--EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCV--------------DGSAPN--------FLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF EE+KF+Q+ +E ++K++ +EG V  EE   LP+ ++++++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP F++   +              D SAP+        F D FF++ET C  WFS EF+VR   CPS+    K++ N +DI++ILPY++TL
Sbjct:  247 NVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLIMALSAGGHSRLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITL 420

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Match: A0A183A880 (BTB domain-containing protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS3165 PE=3 SV=1)

HSP 1 Score: 215.312 bits (547), Expect = 2.051e-62
Identity = 94/158 (59.49%), Postives = 122/158 (77.22%), Query Frame = 2

Query:    8 VPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVLYSFSC 481
            V DD+FL EL+FFQIE++ +  YK  EG+V E  +LP+ ++++KLW+LFEYPETS LA+   + S+IFT+ISIILFCVETLPV+ +THC  G+ PNF D FF+IET CT WF+ E I+R   CPS  A IKD KN +D+ AI+PYY+TLVNVL +FSC
Sbjct:  531 VADDVFLRELEFFQIEEDALESYKKHEGYVPEVIILPENQFKRKLWLLFEYPETSPLAFCFSVTSVIFTIISIILFCVETLPVYAQTHCEPGAKPNFRDPFFIIETICTIWFTFELIIRFSSCPSHKAFIKDFKNLIDLAAIVPYYITLVNVLITFSC 688

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Match: A0A267H803 (BTB domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000942g2 PE=3 SV=1)

HSP 1 Score: 206.838 bits (525), Expect = 1.689e-61
Identity = 96/159 (60.38%), Postives = 126/159 (79.25%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVLYSFSC 481
            +V DDIFL EL+F++IE+EV+  YK +EG++ ET VLP+   ++K+W+LFEYPETS  A+ + +IS++FT+ISIILFCVETL  FK++HCV    PNFLD FF+IE+ CTAWF+LE ++R  VCPSK A IKD+KN VD  AI+PYYVTL NVL + SC
Sbjct:  202 NVTDDIFLSELEFYEIEREVIDAYKKDEGYISETVVLPEHPVKRKIWMLFEYPETSTPAFLVAIISVLFTVISIILFCVETLKEFKDSHCVAHELPNFLDPFFIIESACTAWFTLELVIRFAVCPSKKAFIKDIKNAVDFSAIVPYYVTLTNVLITMSC 360

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Match: A0A267DW52 (BTB domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000942g3 PE=3 SV=1)

HSP 1 Score: 206.453 bits (524), Expect = 2.206e-61
Identity = 96/159 (60.38%), Postives = 126/159 (79.25%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVLYSFSC 481
            +V DDIFL EL+F++IE+EV+  YK +EG++ ET VLP+   ++K+W+LFEYPETS  A+ + +IS++FT+ISIILFCVETL  FK++HCV    PNFLD FF+IE+ CTAWF+LE ++R  VCPSK A IKD+KN VD  AI+PYYVTL NVL + SC
Sbjct:  202 NVTDDIFLSELEFYEIEREVIDAYKKDEGYISETVVLPEHPVKRKIWMLFEYPETSTPAFLVAIISVLFTVISIILFCVETLKEFKDSHCVAHELPNFLDPFFIIESACTAWFTLELVIRFAVCPSKKAFIKDIKNAVDFSAIVPYYVTLTNVLITMSC 360

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Match: A0A267FZA9 (BTB domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000942g4 PE=3 SV=1)

HSP 1 Score: 205.682 bits (522), Expect = 2.614e-61
Identity = 96/159 (60.38%), Postives = 126/159 (79.25%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVLYSFSC 481
            +V DDIFL EL+F++IE+EV+  YK +EG++ ET VLP+   ++K+W+LFEYPETS  A+ + +IS++FT+ISIILFCVETL  FK++HCV    PNFLD FF+IE+ CTAWF+LE ++R  VCPSK A IKD+KN VD  AI+PYYVTL NVL + SC
Sbjct:  202 NVTDDIFLSELEFYEIEREVIDAYKKDEGYISETVVLPEHPVKRKIWMLFEYPETSTPAFLVAIISVLFTVISIILFCVETLKEFKDSHCVAHELPNFLDPFFIIESACTAWFTLELVIRFAVCPSKKAFIKDIKNAVDFSAIVPYYVTLTNVLITMSC 360

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Match: A0A430PX56 (Ion_trans domain-containing protein (Fragment) OS=Schistosoma bovis OX=6184 GN=DC041_0001353 PE=3 SV=1)

HSP 1 Score: 199.904 bits (507), Expect = 7.292e-61
Identity = 92/158 (58.23%), Postives = 121/158 (76.58%), Query Frame = 2

Query:    8 VPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVLYSFSC 481
            V DD+FL EL+FFQIE E +  YK  EG+V +  VLP+   ++KLW+LFEYPETS+LA+T  + S IFT+ISIILFC+ETLPV+ +THC  G+ PNF D FF+IET CT WF++E  +R + CPS+   IKD+KN +D+ AI+PYY+TL NVL +FSC
Sbjct:    9 VSDDVFLTELEFFQIESEALDVYKKNEGYVPDIIVLPENLIKRKLWMLFEYPETSILAFTFSMASFIFTVISIILFCIETLPVYAQTHCEPGTKPNFRDPFFIIETLCTFWFTIEIFIRFISCPSQKIFIKDIKNLIDLAAIVPYYITLFNVLITFSC 166

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Match: ENSAMXT00000041810.1 (shaker-related potassium channel tsha2-like [Source:NCBI gene;Acc:103046217])

HSP 1 Score: 147.902 bits (372), Expect = 2.115e-42
Identity = 72/166 (43.37%), Postives = 106/166 (63.86%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKE---THCVDGSAPN------------FLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIFLEE+KF++I ++VV  +  +EG   EE   +P   +QQ+LW+LFE+P++S  A  I ++S++  LISI +FC+ETLP F++    H  D  A N            ++D FF++E+ C AWFS E + R   CPSK A  KD+ NT+D++AI PY+V L
Sbjct:  136 NVPVDIFLEEIKFYEIGEDVVEGFLEDEGLTREEERPMPSSAFQQQLWLLFEFPDSSSAARVIAVVSVMVILISIAVFCLETLPEFRQETDVHTNDHLASNATHHGGQEPPLWYMDPFFMLESLCIAWFSFELLARFFACPSKTAFYKDIMNTIDLVAIAPYFVVL 301

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:NCBI gene;Acc:103031324])

HSP 1 Score: 145.206 bits (365), Expect = 2.901e-41
Identity = 70/169 (41.42%), Postives = 109/169 (64.50%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETH--------------CVDGSAP----NFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP D+F EE++F+Q+ +E + K++ +EG + EE   LP  ++Q+++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP F++                  +G+AP     F D FF+IET C  WFS E +VR   CPSK    K++ N +DI+AI+PY++TL
Sbjct:  138 NVPIDVFSEEIRFYQLGEEAMEKFREDEGFIKEEERPLPSREFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDDREAAAAAAAAAAAVPLNNGTAPYGPGAFTDPFFVIETLCIVWFSFELLVRFFACPSKATFSKNIMNIIDIVAIIPYFITL 306

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Match: kcna1a (potassium voltage-gated channel subfamily A member 1 [Source:NCBI gene;Acc:103039047])

HSP 1 Score: 139.813 bits (351), Expect = 1.815e-39
Identity = 69/160 (43.12%), Postives = 107/160 (66.88%), Query Frame = 2

Query:    8 VPDDIFLEELKFFQIEKEVVMKYKLEEGHVEET-FVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKET-----HCVDGSA----PNFL-DSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            VP D+F EE+KF+++  E + K++ +EG + E    LP+ ++Q+++W+LFE+PE+S  A  I ++S+   L+SI++FC+ETLP  KE        +  S     P+ L D FF++ET C  WFS E IVR + CPSK A  KD+ NT+D++AI+PY++TL
Sbjct:  105 VPLDMFSEEIKFYELGYEAMEKFREDEGFIREKERPLPEAEFQRQIWLLFEHPESSGPARGIAIVSVTVILVSIVIFCLETLPQLKENPEGHIQIIGNSTFYYKPSLLTDPFFIVETLCIIWFSFELIVRFLACPSKAAFFKDMMNTIDVVAIIPYFITL 264

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Match: ENSAMXT00000027012.2 (potassium voltage-gated channel subfamily A member 2-like [Source:NCBI gene;Acc:103027793])

HSP 1 Score: 137.117 bits (344), Expect = 2.792e-38
Identity = 68/184 (36.96%), Postives = 109/184 (59.24%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKE-----THCVDGSAP----------------------------NFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP D+F EE++F+++ +E + K++ +EG + EE   LP G++Q+++W+LFEYPE+S  A  I ++S++  L+SI++FC+ETLP F++     T    G+ P                             F D FF++ET C  WFS E +VR   CPSK    K++ N +DI+AI+PY++TL
Sbjct:  146 NVPIDVFTEEIRFYELGEEAMEKFREDEGFIKEEERALPAGEFQRQVWLLFEYPESSGPARGIAIVSVLVILVSIVIFCLETLPEFRDDDSDVTRDRVGTTPLHMLNHYPNEMHGHGNLTGGLPPILSGTPFSDPFFVVETLCIVWFSFELLVRFFACPSKATFSKNIMNIIDIVAIIPYFITL 329

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BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Match: kcna7 (potassium voltage-gated channel subfamily A member 7-like [Source:NCBI gene;Acc:103039250])

HSP 1 Score: 133.265 bits (334), Expect = 8.022e-37
Identity = 65/169 (38.46%), Postives = 102/169 (60.36%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGH-VEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPN------------------FLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF++EL+F+ + ++++ ++K +EG   EE   LP  + Q+KLW+LFE+PE+S  A  I +IS++  ++SI++FC+ETLP F+    +    P+                  F D FF++ET C  WFS E ++R    PSK    KD+ N +D  AI+PY+VTL
Sbjct:  137 NVPLDIFMDELRFYDLGEDIMNRFKEDEGFPKEEPRPLPDNELQRKLWMLFEHPESSGGARIIAIISVMVIVVSILIFCLETLPEFRNERELREQTPSHLHHPTTNSTVPFLPASPFQDPFFMVETMCICWFSFELVMRFACSPSKMHFFKDVMNVIDFFAIIPYFVTL 305

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221])

HSP 1 Score: 125.176 bits (313), Expect = 1.057e-34
Identity = 69/161 (42.86%), Postives = 110/161 (68.32%), Query Frame = 2

Query:    8 VPDDIFLEELKFFQIEKEVVMKYKLEEGHVEE-TFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKE-------THCVDGSA----PNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            VP DIF EE++F+ + +E +++Y+ +EG+V+E    LP+ ++Q+++W+LFEYPE+S  A  I ++S++  LISII+FC+ETLP F++       ++  +G+       F D FF++ET C  WFS E +VR   CPSK    K+L N +DI+AI+PY++TL
Sbjct:  109 VPYDIFTEEVRFYDLGEETMLRYREDEGYVKEPEKPLPENEFQRQVWLLFEYPESSSPARAIAIVSVLVILISIIIFCLETLPEFRDDADLYKVSYYTNGTHYFYHNVFADPFFIMETICIIWFSFELMVRFCACPSKVEFGKNLMNIIDIVAIVPYFITL 269

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Match: kcna1b (potassium voltage-gated channel, shaker-related subfamily, member 1b [Source:ZFIN;Acc:ZDB-GENE-140515-1])

HSP 1 Score: 123.25 bits (308), Expect = 1.087e-34
Identity = 61/159 (38.36%), Postives = 94/159 (59.12%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNF--------LDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLV 457
            DVP D+F EE++F+++ +E V KY        E   +    +QQ +W LFE  + S+ A  + L+S + T++SI + C+ETLP F++ + V  +   F        LD FF++ET C  WF  E  VR   CPSK + +KD  N +DI+AI+PY++T+V
Sbjct:   79 DVPSDVFREEVEFYELGEEAVAKYGENTLDTPEEENVHGKDFQQHVWRLFESRDGSIAAKMLSLMSFVTTILSITVMCLETLPQFRKDNQVHANRTEFSIRTSIYNLDPFFMLETACVVWFIFELAVRFYACPSKTSFMKDFMNAIDILAIMPYFITVV 237

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Match: kcna1b (potassium voltage-gated channel, shaker-related subfamily, member 1b [Source:ZFIN;Acc:ZDB-GENE-140515-1])

HSP 1 Score: 123.25 bits (308), Expect = 1.179e-34
Identity = 61/159 (38.36%), Postives = 94/159 (59.12%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNF--------LDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLV 457
            DVP D+F EE++F+++ +E V KY        E   +    +QQ +W LFE  + S+ A  + L+S + T++SI + C+ETLP F++ + V  +   F        LD FF++ET C  WF  E  VR   CPSK + +KD  N +DI+AI+PY++T+V
Sbjct:   71 DVPSDVFREEVEFYELGEEAVAKYGENTLDTPEEENVHGKDFQQHVWRLFESRDGSIAAKMLSLMSFVTTILSITVMCLETLPQFRKDNQVHANRTEFSIRTSIYNLDPFFMLETACVVWFIFELAVRFYACPSKTSFMKDFMNAIDILAIMPYFITVV 229

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Match: kcna1b (potassium voltage-gated channel, shaker-related subfamily, member 1b [Source:ZFIN;Acc:ZDB-GENE-140515-1])

HSP 1 Score: 123.25 bits (308), Expect = 1.236e-34
Identity = 61/159 (38.36%), Postives = 94/159 (59.12%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNF--------LDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLV 457
            DVP D+F EE++F+++ +E V KY        E   +    +QQ +W LFE  + S+ A  + L+S + T++SI + C+ETLP F++ + V  +   F        LD FF++ET C  WF  E  VR   CPSK + +KD  N +DI+AI+PY++T+V
Sbjct:   75 DVPSDVFREEVEFYELGEEAVAKYGENTLDTPEEENVHGKDFQQHVWRLFESRDGSIAAKMLSLMSFVTTILSITVMCLETLPQFRKDNQVHANRTEFSIRTSIYNLDPFFMLETACVVWFIFELAVRFYACPSKTSFMKDFMNAIDILAIMPYFITVV 233

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221])

HSP 1 Score: 121.324 bits (303), Expect = 2.569e-33
Identity = 67/161 (41.61%), Postives = 104/161 (64.60%), Query Frame = 2

Query:   17 DIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKE--------THCVDGS------APNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            D+F EE+KF+++  E + K++ +EG + EE   LP  ++Q+++W+LFEYPE+S  A  I ++S++  LISII+FC+ETLP F++           ++G+        +F D FF++ET C  WFS E +VR   CPSK    K + N +DI+AILPY++TL
Sbjct:  102 DVFSEEIKFYELGNEAMAKFQEDEGFIKEEEKPLPSDEFQRQVWLLFEYPESSNPARGIAIVSVLVILISIIIFCLETLPEFRDEKEQKFLPAKDINGTQVKIMHGSSFTDPFFIVETICIIWFSFELLVRFFACPSKPGFFKSIMNIIDIVAILPYFITL 262

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Match: SHAK4 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHB6])

HSP 1 Score: 108.227 bits (269), Expect = 1.599e-28
Identity = 60/160 (37.50%), Postives = 99/160 (61.88%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMK-YKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETH-----CVDGS----APNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP D+F +E++F+++  +V+ K  + E    EE  +LP+ K Q+++W LFE+P+TS+ A  + + S+    +SI+ FC+ETLP F++        V+G+       F   +F +ET C  WF+ E+I+RL+  P K   I+   N +DI+AILPYY+TL
Sbjct:  128 NVPMDVFADEIRFYELGDDVLHKVEQEEGYIEEEKPILPENKLQRQIWQLFEFPDTSMPARFVAIFSVFVITLSIVTFCIETLPQFQKKEEDLYVSVNGTLVPVDNRFDQPWFSMETACIIWFTFEYIMRLISSPQKLIFIRSFLNMIDIVAILPYYITL 287

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Match: SHAK6 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFM4])

HSP 1 Score: 105.916 bits (263), Expect = 5.911e-28
Identity = 56/163 (34.36%), Postives = 96/163 (58.90%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLE-EGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFK------------ETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            ++P  +F+ ++K+F + ++ + +   + E    E   +PK K+Q+ +W LFE+P+TS  A  I + S+   ++SI+LFCVETLP F+            ET  +D    +    FF IE+FC AWF+LE+ +R +  P K   +  + N +D++AILP+++TL
Sbjct:   71 NIPRKVFVSDIKYFDLGEQALRQAGDDLEITDREIRPMPKNKFQRTVWSLFEHPDTSNGARAIAIFSVAVIVLSIVLFCVETLPQFQRRPKEVLRNNITETIMIDNPKKSV---FFAIESFCIAWFTLEYFIRFLCSPDKCKFVVSVLNLIDLVAILPFFITL 230

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Match: SHAKR7 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIU2])

HSP 1 Score: 106.686 bits (265), Expect = 6.766e-28
Identity = 60/152 (39.47%), Postives = 93/152 (61.18%), Query Frame = 2

Query:    8 VPDDIFLEELKFFQIEKEVV-MKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVE-TLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLV 457
            +P++IF+EE++FF+I  +++  + +LEE  + +  VLPK  +Q+K+W+ F  PE+S LA  I L S++  LIS+I+ CVE +L  F ET  +  S     + + +IE  C  WF++E I RL   P K    K   N VDI+ +LPYY+ L 
Sbjct:   90 LPENIFVEEVRFFEIPSDLITAREELEEKLMGKNAVLPKNDHQKKIWLAFSVPESSFLARVIALWSVMVILISVIIPCVESSLLEFNET-SIGNSNVLATNVYVIIEMACYIWFTIELIFRLASAPEKIKFCKQPLNVVDILTVLPYYIVLA 240

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Match: SHAK3 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK45])

HSP 1 Score: 105.145 bits (261), Expect = 1.774e-27
Identity = 60/168 (35.71%), Postives = 97/168 (57.74%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMK-YKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSA-PNFL----------------DSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
             VP  +F +E+ FF++ K+ + +  + E    E T VLP+   Q+++W LFEYP++S+ A  + + S+   LISI++FC+ETLP F+     DG+  P  L                 ++  +E  C AWF+LE++VRL+  P K   ++   N +D++AILPYY+TL
Sbjct:   71 GVPFLLFKDEVIFFKLGKDNLKRLEEEEGYIEETTRVLPRHHLQRRIWELFEYPDSSMGARVLAVWSVSVILISIVVFCIETLPTFRCKTSPDGNGCPKLLPGTNSTADHPEPVEKSSAWLALEILCIAWFTLEYVVRLLSSPQKLLFVRSFLNVIDLMAILPYYITL 238

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Match: SHAKR1 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3Y6])

HSP 1 Score: 97.4413 bits (241), Expect = 6.854e-25
Identity = 52/153 (33.99%), Postives = 87/153 (56.86%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFV---LPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            D+    F+ E+ FF++E   ++ ++  E +  +T +   +P    Q+K+W + E P +S  A  + + S+   L+SI++FC+ETLP  +ET     SA       + IE  C AWF+LE ++R + CP+K   I    N +D++AILPYY+ L
Sbjct:   71 DLDMKTFVNEVYFFELED--LVSHQFIEAYGSDTSLVSKMPDNAIQRKIWEVLELPHSSFTAQVVAVWSVGVILLSIVVFCIETLPGLRETRTEKSSA------LYSIEILCVAWFTLELLLRFLTCPNKPHFIISFLNIIDVLAILPYYIML 215

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Match: ENSORLT00000025729.2 (shaker-related potassium channel tsha2 [Source:NCBI gene;Acc:101167693])

HSP 1 Score: 151.754 bits (382), Expect = 3.885e-44
Identity = 74/164 (45.12%), Postives = 113/164 (68.90%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKE-------------THCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF+EE+KF+++ +EV+  +K +EG + EE   LP+ ++Q+++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP F+E             T   D + P F D FF++ET C  WFS E +VR + CPSK A  K++ NT+DI+AI+PY++TL
Sbjct:  106 NVPVDIFMEEIKFYELGEEVIENFKEDEGFIKEEERPLPEHEFQRQVWLLFEYPESSGAARGIAIVSVLVILISIVIFCLETLPEFREDARDLEAQPYVNGTASADRANP-FTDPFFIVETLCIIWFSFELLVRFLACPSKPAFFKNIMNTIDIVAIMPYFITL 268

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Match: ENSORLT00000004658.2 (pep primary_assembly:ASM223467v1:6:13425755:13435070:-1 gene:ENSORLG00000003738.2 transcript:ENSORLT00000004658.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 146.747 bits (369), Expect = 2.268e-42
Identity = 74/160 (46.25%), Postives = 110/160 (68.75%), Query Frame = 2

Query:    8 VPDDIFLEELKFFQIEKEVVMKYKLEEG-HVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKET-----HCVDGSAPN-----FLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            VP DIFLEELKF+++E+EV+  +K +EG   EE   LP  ++Q+++W+LFEYPE+S  A  I ++S++  LISI++FC+ETLP FK+      +  +GSA       F D FF++ET C  WFS EF++R + CPSK    K++ N +D++AI PY++TL
Sbjct:  104 VPVDIFLEELKFYELEEEVIELFKDDEGLPREEERPLPSNEFQRQVWLLFEYPESSGPARMIAIVSVMVILISIVIFCLETLPEFKDVPPEPDNHANGSAHGKEPSPFTDPFFMVETLCIVWFSFEFMMRFLSCPSKPVFFKNIMNLIDVVAIAPYFITL 263

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3-like [Source:NCBI gene;Acc:105354379])

HSP 1 Score: 142.51 bits (358), Expect = 3.401e-40
Identity = 67/163 (41.10%), Postives = 112/163 (68.71%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETH--------CVDGSAPNFL----DSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF EE++F+++ +E + K++ +EG + EE   LP+ ++Q+++W+LFEYPE+S  A  + ++S++  LISI++FC+ETLP F++ +         ++G+ P F+    D FF++ET C  WFS E +VR   CPSK    K++ N +DI+AI+PY++TL
Sbjct:  144 NVPIDIFSEEIRFYELGEEAMEKFREDEGFIKEEERPLPENEFQRQVWLLFEYPESSGPARGVAIVSVLVILISIVIFCLETLPEFRDENNDVITLAPVINGTVPYFISPFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSKNIMNIIDIVAIVPYFITL 306

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Match: kcna1a (potassium voltage-gated channel subfamily A member 1 [Source:NCBI gene;Acc:101161480])

HSP 1 Score: 140.198 bits (352), Expect = 1.146e-39
Identity = 71/161 (44.10%), Postives = 110/161 (68.32%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHV-EETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFK-----ETHCVDGSA----PN-FLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP D+F EE+KF+++  + + +++ +EG + EE   LP+ ++Q+++W+LFE+PE+S  A  I ++S++  LISI++FC+ETLP  K       + V  S     PN F D FF+IET C  WFS E IVR + CPSK A  K++ NT+DI+AI+PY++TL
Sbjct:  104 NVPLDMFSEEIKFYELGVDAMERFREDEGFIREEERPLPEKEFQRQMWLLFEHPESSNTARGIAIVSVMVILISIVIFCLETLPQLKVDSTGHFYSVGNSTFYYKPNIFTDPFFVIETLCIIWFSFELIVRFLACPSKPAFFKNMMNTIDIVAIIPYFITL 264

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Match: kcna7 (potassium voltage-gated channel subfamily A member 7-like [Source:NCBI gene;Acc:101163081])

HSP 1 Score: 140.969 bits (354), Expect = 1.625e-39
Identity = 72/170 (42.35%), Postives = 107/170 (62.94%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGH-VEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKE--------THCVDGSAPN-----------FLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTL 454
            +VP DIF+EEL F+++ +E + ++K +EG   EE   LP  K+QQK+W+LFEYPE+S  A  I +IS++  ++SI++FC+ETLP F++        T     + PN           F D FF++ET C  WFS E I+R +  PSK +  KD+ N +D +AILPY+VT+
Sbjct:  141 NVPLDIFMEELHFYELGEETIDRFKEDEGFPKEEERPLPAKKWQQKIWMLFEYPESSGGARIIAIISVMVIILSILIFCLETLPEFRQEKERREQYTITPHPTIPNETVQVPPKFTPFHDPFFIVETICICWFSFELIMRFISAPSKMSFFKDVMNVIDFLAILPYFVTV 310

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Match: SMESG000014198.1 (SMESG000014198.1)

HSP 1 Score: 327.405 bits (838), Expect = 3.775e-113
Identity = 161/161 (100.00%), Postives = 161/161 (100.00%), Query Frame = 2

Query:    2 FDVPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVLYSFSCS 484
            FDVPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVLYSFSCS
Sbjct:  113 FDVPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVLYSFSCS 273

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Match: SMESG000014206.1 (SMESG000014206.1)

HSP 1 Score: 323.553 bits (828), Expect = 1.063e-111
Identity = 160/161 (99.38%), Postives = 160/161 (99.38%), Query Frame = 2

Query:    2 FDVPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVLYSFSCS 484
            FDV DDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVLYSFSCS
Sbjct:  113 FDVLDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVLYSFSCS 273

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Match: SMESG000013562.1 (SMESG000013562.1)

HSP 1 Score: 195.667 bits (496), Expect = 5.253e-61
Identity = 87/159 (54.72%), Postives = 120/159 (75.47%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVLYSFSC 481
            +VPD+IFL EL F+QIEK V+  YK +EGH  E   LP  K ++ +W+LFE+PETS+ A+ + ++S+ FT++SI+LFCVET P F ++HCV G+APNFLD FF++ET CT WF++E   R + CPSK   IKD+KN +D+ A++PYYVTL NVL +F C
Sbjct:  170 NVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDC 328

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Match: SMESG000006565.1 (SMESG000006565.1)

HSP 1 Score: 168.703 bits (426), Expect = 3.821e-51
Identity = 73/159 (45.91%), Postives = 114/159 (71.70%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVLYSFSC 481
            +VP+D+FL E+++F++E  V+  +  ++G+V E   LP     QK+W+LFEYPETS  AY +G++S++ T++SI  FC+ET+P + +  C+D    NFL  FF+ ET CT WF++E I RLV CP+   ++KD KN +DI+A++PYY+TL N+L+S +C
Sbjct:  118 NVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKM-CIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNC 275

[Close]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Match: SMESG000061194.1 (SMESG000061194.1)

HSP 1 Score: 143.28 bits (360), Expect = 5.369e-40
Identity = 66/170 (38.82%), Postives = 108/170 (63.53%), Query Frame = 2

Query:    5 DVPDDIFLEELKFFQIEKEVVMKYKLEEGH-VEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSA---------------PNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVL 466
            +VP D+F+EE+KF+++ +E + KY+ +EG+  EE  VLP+ ++Q+++W+LFEYPE+S  A  + ++S+   ++SI++FCVETLP FK    ++ +                P F + FF+IET C  WF+ E +VR    P K    K++ N +DI+AI+PY++TL   L
Sbjct:  135 NVPMDVFMEEIKFYELGEEAIDKYREDEGYNKEEVKVLPENEFQRRVWLLFEYPESSTSARCVAILSVFVIVLSIVIFCVETLPHFKYYKMINKTTHSDSVQQIEFEEDDIPKFTEPFFVIETCCIVWFTFELLVRFASSPRKLDFFKNIMNLIDIVAIIPYFITLGTAL 304

The following BLAST results are available for this feature:

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Zebrafish
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Yeast
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KCNA3	3.515e-40	40.00	potassium voltage-gated channel subfamily A member...	[more]
KCNA2	1.233e-39	40.48	potassium voltage-gated channel subfamily A member...	[more]
KCNA1	1.388e-39	42.33	potassium voltage-gated channel subfamily A member...	[more]
KCNA4	1.815e-39	41.38	potassium voltage-gated channel subfamily A member...	[more]
KCNA1	3.049e-39	42.33	potassium voltage-gated channel subfamily A member...	[more]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
shk-1	4.873e-29	37.11	Potassium voltage-gated channel protein shk-1 [So...	[more]
shk-1	6.698e-29	37.11	Potassium voltage-gated channel protein shk-1 [So...	[more]
shk-1	1.619e-28	37.11	Potassium voltage-gated channel protein shk-1 [So...	[more]
shk-1	1.619e-28	37.11	Potassium voltage-gated channel protein shk-1 [So...	[more]
shk-1	1.801e-27	37.34	Potassium voltage-gated channel protein shk-1 [So...	[more]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Sh	1.746e-41	41.82	gene:FBgn0003380 transcript:FBtr0308199	[more]
Sh	2.128e-41	41.82	gene:FBgn0003380 transcript:FBtr0089659	[more]
Sh	2.128e-41	41.82	gene:FBgn0003380 transcript:FBtr0301955	[more]
Sh	5.028e-41	41.82	gene:FBgn0003380 transcript:FBtr0332299	[more]
Sh	6.352e-41	41.82	gene:FBgn0003380 transcript:FBtr0089663	[more]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kcna1b	5.180e-40	43.48	potassium voltage-gated channel, shaker-related su...	[more]
kcna1b	5.180e-40	43.48	potassium voltage-gated channel, shaker-related su...	[more]
kcna1a	7.627e-39	44.72	potassium voltage-gated channel, shaker-related su...	[more]
kcna1a	7.627e-39	44.72	potassium voltage-gated channel, shaker-related su...	[more]
CABZ01113981.1	8.019e-39	45.22	pep scaffold:GRCz11:KN150008.1:12653:14179:-1 gene...	[more]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KCNA4	1.475e-40	40.78	potassium voltage-gated channel subfamily A member...	[more]
KCNA3	3.229e-40	41.72	potassium voltage-gated channel subfamily A member...	[more]
KCNA2	1.734e-39	42.86	potassium channel, voltage gated shaker related su...	[more]
fastkd3	1.577e-38	42.59	FAST kinase domains 3 [Source:Xenbase;Acc:XB-GENE-...	[more]
KCNA1	1.887e-38	41.88	potassium channel, voltage gated shaker related su...	[more]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Kcna3	9.205e-40	40.00	potassium voltage-gated channel, shaker-related su...	[more]
Kcna4	1.090e-39	41.38	potassium voltage-gated channel, shaker-related su...	[more]
Kcna1	2.885e-39	42.33	potassium voltage-gated channel, shaker-related su...	[more]
Kcna1	2.885e-39	42.33	potassium voltage-gated channel, shaker-related su...	[more]
Kcna2	1.211e-38	39.88	potassium voltage-gated channel, shaker-related su...	[more]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P22001\|KCNA3_HUMAN	1.688e-39	40.00	Potassium voltage-gated channel subfamily A member...	[more]
sp\|P16390\|KCNA3_MOUSE	6.439e-39	40.00	Potassium voltage-gated channel subfamily A member...	[more]
sp\|P15385\|KCNA4_RAT	7.438e-39	41.38	Potassium voltage-gated channel subfamily A member...	[more]
sp\|Q28527\|KCNA4_MUSPF	7.546e-39	41.38	Potassium voltage-gated channel subfamily A member...	[more]
sp\|Q61423\|KCNA4_MOUSE	7.622e-39	41.38	Potassium voltage-gated channel subfamily A member...	[more]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A183A880	2.051e-62	59.49	BTB domain-containing protein OS=Echinostoma capro...	[more]
A0A267H803	1.689e-61	60.38	BTB domain-containing protein OS=Macrostomum ligna...	[more]
A0A267DW52	2.206e-61	60.38	BTB domain-containing protein OS=Macrostomum ligna...	[more]
A0A267FZA9	2.614e-61	60.38	BTB domain-containing protein OS=Macrostomum ligna...	[more]
A0A430PX56	7.292e-61	58.23	Ion_trans domain-containing protein (Fragment) OS=...	[more]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000041810.1	2.115e-42	43.37	shaker-related potassium channel tsha2-like [Sourc...	[more]
KCNA3	2.901e-41	41.42	potassium voltage-gated channel subfamily A member...	[more]
kcna1a	1.815e-39	43.13	potassium voltage-gated channel subfamily A member...	[more]
ENSAMXT00000027012.2	2.792e-38	36.96	potassium voltage-gated channel subfamily A member...	[more]
kcna7	8.022e-37	38.46	potassium voltage-gated channel subfamily A member...	[more]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KCNA3	1.057e-34	42.86	potassium voltage-gated channel subfamily A member...	[more]
kcna1b	1.087e-34	38.36	potassium voltage-gated channel, shaker-related su...	[more]
kcna1b	1.179e-34	38.36	potassium voltage-gated channel, shaker-related su...	[more]
kcna1b	1.236e-34	38.36	potassium voltage-gated channel, shaker-related su...	[more]
KCNA3	2.569e-33	41.61	potassium voltage-gated channel subfamily A member...	[more]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
SHAK4	1.599e-28	37.50	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
SHAK6	5.911e-28	34.36	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
SHAKR7	6.766e-28	39.47	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
SHAK3	1.774e-27	35.71	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
SHAKR1	6.854e-25	33.99	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000025729.2	3.885e-44	45.12	shaker-related potassium channel tsha2 [Source:NCB...	[more]
ENSORLT00000004658.2	2.268e-42	46.25	pep primary_assembly:ASM223467v1:6:13425755:134350...	[more]
KCNA3	3.401e-40	41.10	potassium voltage-gated channel subfamily A member...	[more]
kcna1a	1.146e-39	44.10	potassium voltage-gated channel subfamily A member...	[more]
kcna7	1.625e-39	42.35	potassium voltage-gated channel subfamily A member...	[more]

BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000014198.1	3.775e-113	100.00	SMESG000014198.1	[more]
SMESG000014206.1	1.063e-111	99.38	SMESG000014206.1	[more]
SMESG000013562.1	5.253e-61	54.72	SMESG000013562.1	[more]
SMESG000006565.1	3.821e-51	45.91	SMESG000006565.1	[more]
SMESG000061194.1	5.369e-40	38.82	SMESG000061194.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30010596 ID=SMED30010596|Name=Potassium voltage-gated channel subfamily A member 2|organism=Schmidtea mediterranea sexual|type=transcript|length=485bp
GTTTGATGTCCCGGATGATATATTCTTAGAAGAACTCAAGTTTTTTCAAA
TAGAAAAAGAAGTGGTCATGAAATACAAGTTAGAAGAAGGGCACGTAGAG
GAGACTTTTGTTCTTCCAAAAGGGAAATACCAGCAAAAACTTTGGATTCT
TTTTGAATATCCCGAAACTAGTTTATTAGCTTACACAATTGGCTTGATTT
CTATGATTTTCACACTGATTTCTATAATTTTATTTTGTGTTGAAACTTTA
CCTGTTTTCAAAGAAACGCATTGCGTTGATGGCTCGGCACCAAATTTTTT
GGATTCATTCTTTTTAATAGAAACATTTTGCACCGCTTGGTTTTCTCTTG
AATTTATTGTCCGATTAGTCGTCTGTCCATCAAAAAACGCGCACATCAAA
GACCTGAAAAATACGGTTGATATTATAGCAATTCTTCCATATTACGTAAC
TTTAGTAAATGTGCTTTATTCCTTCAGTTGCTCTG

protein sequence of SMED30010596-orf-1

>SMED30010596-orf-1 ID=SMED30010596-orf-1|Name=SMED30010596-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=161bp
FDVPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWIL
FEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFL
DSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVT
LVNVLYSFSCS

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000105	secretory cell
PLANA:0000143	ventral region of the whole animal
PLANA:0000418	head
PLANA:0000420	parapharyngeal region
PLANA:0000481	serotonergic neuron

Vocabulary: **INTERPRO**
Term	Definition
IPR028325	VG_K_chnl
IPR003972	K_chnl_volt-dep_Kv1
IPR027359	Volt_channel_dom_sf
IPR005821	Ion_trans_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005249	voltage-gated potassium channel activity
GO:0005216	ion channel activity
GO:0005244	voltage-gated ion channel activity
GO:0005267	potassium channel activity

Vocabulary: **biological process**
Term	Definition
GO:0006813	potassium ion transport
GO:0006811	ion transport
GO:0055085	transmembrane transport
GO:0006810	transport
GO:0034765	regulation of ion transmembrane transport
GO:0051260	protein homooligomerization
GO:0071805	potassium ion transmembrane transport

Vocabulary: **cellular component**
Term	Definition
GO:0008076	voltage-gated potassium channel complex
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PRINTS	PR00169	KCHANNEL	coord: 131..151 score: 42.51 coord: 54..82 score: 39.96 coord: 105..128 score: 45.36
None	No IPR available	PANTHER	PTHR11537:SF255	POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 6	coord: 2..152
None	No IPR available	CDD	cd18407	BTB_POZ_KCNA6	coord: 2..57 e-value: 1.15892E-12 score: 59.2409
None	No IPR available	SUPERFAMILY	SSF81324	Voltage-gated potassium channels	coord: 60..153
None	No IPR available	TMHMM	TMhelix		coord: 139..158
None	No IPR available	TMHMM	TMhelix		coord: 102..124
None	No IPR available	TMHMM	TMhelix		coord: 58..80
IPR003972	Potassium channel, voltage dependent, Kv1	PRINTS	PR01496	SHAKERCHANEL	coord: 74..85 score: 68.7 coord: 51..67 score: 52.65
IPR005821	Ion transport domain	PFAM	PF00520	Ion_trans	coord: 64..155 e-value: 3.2E-9 score: 36.4
IPR027359	Voltage-dependent channel domain superfamily	GENE3D	G3DSA:1.20.120.350		coord: 32..158 e-value: 1.6E-32 score: 114.3
IPR028325	Voltage-gated potassium channel	PANTHER	PTHR11537	VOLTAGE-GATED POTASSIUM CHANNEL	coord: 2..152

Main menu

Potassium voltage-gated channel subfamily A member 2

Zeng et. al., 2018

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Owlery

blazegraph-runner