Gln-synt_C domain-containing protein

Overview
NameGln-synt_C domain-containing protein
Smed IDSMED30010540
Length (bp)1931
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Gln-synt_C domain-containing protein (SMED30010540) t-SNE clustered cells

Violin plots show distribution of expression levels for Gln-synt_C domain-containing protein (SMED30010540) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Gln-synt_C domain-containing protein (SMED30010540) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Gln-synt_C domain-containing protein (SMED30010540) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30010540

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30010540SMESG000064881.1 dd_Smed_v4_9076_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30010540SMESG000064881.1 dd_Smed_v4_9076_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30010540SMESG000064881.1 dd_Smed_v4_9076_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30010540SMESG000064881.1 Contig42860newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30010540SMESG000064881.1 Contig42860uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30010540SMESG000064881.1 OX_Smed_1.0.07969ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Gln-synt_C domain-containing protein vs. Ensembl Human
Match: LGSN (lengsin, lens protein with glutamine synthetase domain [Source:HGNC Symbol;Acc:HGNC:21016])

HSP 1 Score: 185.652 bits (470), Expect = 6.901e-51
Identity = 134/475 (28.21%), Postives = 225/475 (47.37%), Query Frame = 3 
Query:  453 CYVNGIQII*HLRILKKMSNCKSQLKD--FDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENK-SRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMYKT-TMLAKYEKFFM-DAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLH----NFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGV--VNKIYPPPKGDKSM-------GDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEY 1823
            C  +  QI+   ++  +M + +  +      F+R    DL+G   SK + +   Q   ++ V +  G + + P  +   ++       + +    P+L T + + WAD   R      VI D       P+   PR +A +Q+  L+     L SAF  +F  F +   E  +S +  +   T L  +++ FM + V  L   G +++        GQ+E+  LP FGI++AD AF  + G+KE+A+ +    SF  +    +S      +HSLW    K+N      G + L+     W+ GL+KH  A+S L  P+ +C +R      +        W  ND  C   +K   EK T IEN+L S+ A PY  LAAT+AAG+DG+   N++   P  D+S         ++P   E+AL  LE+D  +++ALGE F+ YF+ +K+     E+      + E++ +ER ++ EY
Sbjct:   56 CMRDSSQILTPPQLSSRMKHIRQAMAKNRLQFVRFEATDLHGVSRSKTIPAHFFQEKVSHGVCMPRGYLEVIPNPKDNEMNNIRATCFNSDIVLMPELSTFRVLPWADRTAR------VICDTFTVTGEPLLTSPRYIAKRQLSHLQASGFSLLSAFIYDFCIFGVP--EILNSKIISFPALTFLNNHDQPFMQELVDGLYHTGANVESFSSSTRPGQMEISFLPEFGISSADNAFTLRTGVKEVARKYNYIASFFIETGFCDSGI---LSHSLWDVDRKKNMFCSTSGTEQLTITGKKWLAGLLKHSAALSCLMAPSVSCRKRYSKDRKDLKKSVPTTWGYNDNSCIFNIKCHGEKGTRIENKLGSATANPYLVLAATVAAGLDGLHSSNEVLAGP--DESTDFYQVEPSEIPLKLEDALVALEEDQCLRQALGETFIRYFVAMKK----YEL------ENEEIAAERNKFLEY 507
[Close]
BLAST of Gln-synt_C domain-containing protein vs. Ensembl Zebrafish
Match: lgsn (lengsin, lens protein with glutamine synthetase domain [Source:ZFIN;Acc:ZDB-GENE-060312-26])

HSP 1 Score: 165.236 bits (417), Expect = 8.178e-43
Identity = 124/423 (29.31%), Postives = 195/423 (46.10%), Query Frame = 3 
Query:  528 KDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTE-NKSRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMY---KTTMLAKYEKFFMDAVTK-LAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRL---------HNFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGV-----VNKIYPPPKGDKSMGDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKR 1739
            ++  F+R    DL+G   SK V ++         + +    + L    Q   +D  +  N S +    PDL T + + WAD   R      +I D       P+   PR++A   + +L+ M   L S+F  E   F      P   G        TT+L+  ++ F+  + K +   G+D++     +G GQ+E+   P FG+ AAD A+ F+ GIKE+A+ +    +F T   +  S      +HSLW  S +R+      GE  LS++   W+ GL+ H  A+S L  P  +C  ++         H +   G      ND  C   VK    + T+I+N+L S+ A PY  LAATIAAG+DG+       ++       +    +P   ++AL  L +D VI  ALGE FV YFI +K+
Sbjct:  247 ENLSFVRFEATDLHGVSRSKTVPARFFHEKAVYGIPMPRSYLELTLSPQINEVDHASAVNFSSDVLLVPDLSTFQILPWADQTAR------LICDPCTITGVPLRTSPRLIAKMMLGQLQSMGFSLHSSFTYECCIFG----SPEHVGPKAVFFPATTLLSNNDQPFLQQLVKGMYNMGVDVESFSSANGPGQMEICFKPRFGMDAADNAYTFRTGIKEMARKYDYIATFFTYENIQNS---GLLSHSLWDASGRRSLFHSGNGE--LSEIGRKWLSGLLHHSAALSCLLAPGISCRTQISKGKKDSKNHVYATCG-----CNDNSCDFNVKIHGGRETHIDNKLASAMANPYIVLAATIAAGLDGIKRNLNAEQVLSRAPNQQKQFVIPVKLDDALLALAEDSVICGALGEPFVQYFIAMKQ 649
[Close]
BLAST of Gln-synt_C domain-containing protein vs. Ensembl Xenopus
Match: pkn2 (protein kinase N2 [Source:Xenbase;Acc:XB-GENE-995298])

HSP 1 Score: 170.244 bits (430), Expect = 9.886e-46
Identity = 130/458 (28.38%), Postives = 214/458 (46.72%), Query Frame = 3 
Query:  528 KDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENKSRNAYFF-------PDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMY-KTTMLAKYEKFFMDAV-TKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLHNFIAPGS--------LNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGV---------VNKIYPPPKGDKSMGDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEY 1823
            +D  FIR    DL+G   SK++  +       + + +      L P    +     +E   + A +F       PDL T + + WA+      K G VI D        +  +PR +A + + +L+E    L ++F  EF  F +   E   S   ++   T++   ++ F+  +   +   G +I+  C     GQ+E+   P +G+ AAD AF F+  +KE+AK +    SF     +    +   F+HSLW  S  +N   D      L+D+   W+ GL+ H  A+S L  P  +C +      A G+          +  ND  CS  VK      TYIEN+L S+AA PY  LAAT+AAG+DG+          N+ + P +    M  +P   E+AL+ L++D  I+ ALG+ F++YFI +K+     E+      + E++++ER ++ EY
Sbjct:   41 EDIHFIRFEVADLHGFPRSKIIPERFFHEKAVSGIHV--SRSYLEPNMNPID----SEADHKKAIYFNSDIVLKPDLSTFRVLPWAE------KTGKVICDAYTIMGDSLLTYPRYLAKQLLMQLQESGFSLHASFNYEFCIFGVA--ETVDSKKVVFPAATLVTDNDQLFLQELFDGMYYIGGNIESFCSSSTPGQMEISFQPEYGLTAADNAFTFRAALKEVAKKYGYISSFCND--VGGIYNSGVFSHSLWDSSGTKNLFIDGNQIQELTDIGRKWLSGLLFHSAALSCLVAPGVSCRKHF----AKGAKDPQESIGATYGFNDNSCSYNVKCHCSSGTYIENKLCSAAANPYLVLAATVAAGLDGIRRGLDLFIDTNRKFSPHQ--FKMHSVPMKMEDALSALKEDRYIRAALGDVFIHYFIAVKQH----EL------ETEEMDTERNKFLEY 466
[Close]
BLAST of Gln-synt_C domain-containing protein vs. Ensembl Xenopus
Match: avpr1b (arginine vasopressin receptor 1B [Source:Xenbase;Acc:XB-GENE-481094])

HSP 1 Score: 167.162 bits (422), Expect = 1.430e-44
Identity = 129/457 (28.23%), Postives = 209/457 (45.73%), Query Frame = 3 
Query:  528 KDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENKSRNAYFF-------PDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMYKTTMLAKYEKFFMDAV-TKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLHNFIAPGS--------LNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGV---------VNKIYPPPKGDKSMGDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEY 1823
            +D  FIR    DL G   SK++  +       + + +      L P    +     +E   + A +F       PDL T + + WA+      K G VI D        +   PR +A + + +L+E    L ++F  EF  F +      S  +     T++   ++ F+  +   +   G +I+  C     GQ+E+   P +G+ AAD AF F+  +KE+AK +    SF     +    +   F+HSLW  S  +N   D      L D+   W+ GL+ H  A+S L  P  +C +      A G+          +  ND  CS  VK      TYIEN+L S+AA PY  LAAT+AAG+DG+          N+ + P +    M  +P   E+AL+ L++D  I+ ALG+ F++YFI +K+     E+      + E++++ER ++ EY
Sbjct:   41 EDIHFIRFEVADLYGFPRSKIIPERFFHEKAVSGIHV--SRSYLEPNMNPID----SEADHKKAIYFNSDIVLKPDLSTFRVLPWAE------KTGKVICDAYTIMGDSLLTSPRYLAKQLLMQLQESGFSLHASFNYEFCIFGVAETVD-SKKVVFPAATLVTDNDQLFLQELFDGMYYIGGNIESFCSSSTPGQMEISFQPEYGLTAADNAFTFRAALKEVAKKYGYISSFCND--VGGIYNSGVFSHSLWDSSGTKNLFIDGNQIQELPDIGRKWLSGLLFHSAALSCLVAPGVSCRKHF----AKGAKDPQESIGATYGFNDNSCSYNVKCHCSSGTYIENKLCSAAANPYLVLAATVAAGLDGIRRGLDLFIDTNRKFSPHQ--FKMHSVPMKMEDALSALKEDRYIRAALGDVFIHYFIAVKQH----EL------ETEEMDTERNKFLEY 466
[Close]
BLAST of Gln-synt_C domain-containing protein vs. Ensembl Mouse
Match: Lgsn (lengsin, lens protein with glutamine synthetase domain [Source:MGI Symbol;Acc:MGI:2672844])

HSP 1 Score: 185.652 bits (470), Expect = 1.115e-50
Identity = 129/460 (28.04%), Postives = 220/460 (47.83%), Query Frame = 3 
Query:  489 RILKKMSNCKSQL--KDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENK-SRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMYKTTMLAKYEKFFM-DAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRL----HNFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDKSM-------GDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEY 1823
            ++  +M + K ++      F+R    DL+G   SK + +Q  Q    + V +  G + L P  +   ++       + +    P+L T + + WA+   R      VI D       P+   PR +A +Q+R+L++    L SAF  +F  F +      S  +    +T+L+ +++ FM + V  L   G +++        GQ+E+  LP FGI++AD AF  + G++E+A+ +    S + +     S      +HS+W    K N      G + L+     W+ GL+KH  A+S L  P  NC +R      +        W  ND  C++ +K   EK T IEN+L S+ A PY  LAAT+AAG+DG+ +        D+S         ++P   E+AL  LE+D+ +K+ALGE F+ YF+ +K+     E+      + E+ ++E  ++ EY
Sbjct:  122 QLSARMKHIKQEMAKNHLQFVRFEATDLHGVSRSKSIPAQFFQEKVIHGVFMPRGYLELMPNPKDNEVNHIRATCFNSDIVLMPELSTFRVLPWAERTAR------VICDTFTVTGEPLLTSPRYIAKRQLRQLQDAGFCLLSAFIYDFCIFGVPEV-INSKTISFPASTLLSNHDQPFMQELVEGLYQTGANVESFSSSTRPGQMEICFLPEFGISSADNAFTLRTGLQEVARRYNYIASLVIETGFCNSGI---LSHSIWDVGGKTNMFCSGSGVERLTLTGKKWLAGLLKHSAALSCLMAPAVNCRKRYCKDSRDLKDSVPTTWGYNDNSCALNIKCHGEKGTQIENKLGSATANPYLVLAATVAAGLDGLQSSDGAAAGSDESQDLYQPEPSEIPLKMEDALAALEQDECLKQALGETFIRYFVAMKK----YEL------ENEETDAEGNKFLEY 561
[Close]
BLAST of Gln-synt_C domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7TT51|LGSN_RAT (Lengsin OS=Rattus norvegicus OX=10116 GN=Lgsn PE=2 SV=1)

HSP 1 Score: 192.2 bits (487), Expect = 3.806e-52
Identity = 131/460 (28.48%), Postives = 223/460 (48.48%), Query Frame = 3 
Query:  489 RILKKMSNCKSQL--KDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENK-SRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMYKTTMLAKYEKFFM-DAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRL----HNFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDKSM-------GDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEY 1823
            ++  +M + K ++      F+R    DL+G   SK + +Q  Q    + V +  G + L P  +   ++       + +    P+L T + + WA+   R      VI D       P+   PR +A +Q+R+L++    L SAF  +F  F +      S  +    +T+L+ +++ FM + V  L   G +++        GQ+E+  LP FGI++AD AF  + G++E+A+ +    S + +     S      +HS+W  S K N  +   G + L+     W+ GL+KH  A+S L  P  NC +R      +        W  ND  C++ VK   EK T IEN+L S+ A PY  LAAT+AAG+DG+ +      + D+S         ++P   E+AL  LE+D+ +K+ALGE F+ YF+ +K+     E+      + E+ ++E  ++ EY
Sbjct:  120 QLSSRMKHIKQEMAKNHLQFVRFEATDLHGVSRSKSIPAQFFQEKVIHGVFMPRGYLELMPNPKDNEVNHIRATCFNSDIVLMPELSTFRVLPWAERTAR------VICDTFTVTGEPLLTSPRYIAKRQLRQLQDAGFSLLSAFIYDFCIFGVPEV-INSKTISFPASTLLSNHDQPFMQELVDGLYHTGANVESFSSSTRPGQMEICFLPEFGISSADNAFTLRTGVQEVARRYNYIASLVIETGFCNSGI---LSHSIWDVSGKTNMFYSGSGVERLTLTGKKWLAGLLKHSAALSCLMAPAVNCRKRYCKDSRDLKDSVPTTWGYNDNSCALNVKCHGEKGTQIENKLGSATANPYLVLAATVAAGLDGLQSSDGAAAESDESQDLYQPEPSEIPLKMEDALAALEQDECLKQALGETFIRYFVAMKK----YEL------ENEETDAEGNKFLEY 559
[Close]
BLAST of Gln-synt_C domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5TDP6|LGSN_HUMAN (Lengsin OS=Homo sapiens OX=9606 GN=LGSN PE=1 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 3.314e-50
Identity = 134/475 (28.21%), Postives = 225/475 (47.37%), Query Frame = 3 
Query:  453 CYVNGIQII*HLRILKKMSNCKSQLKD--FDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENK-SRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMYKT-TMLAKYEKFFM-DAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLH----NFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGV--VNKIYPPPKGDKSM-------GDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEY 1823
            C  +  QI+   ++  +M + +  +      F+R    DL+G   SK + +   Q   ++ V +  G + + P  +   ++       + +    P+L T + + WAD   R      VI D       P+   PR +A +Q+  L+     L SAF  +F  F +   E  +S +  +   T L  +++ FM + V  L   G +++        GQ+E+  LP FGI++AD AF  + G+KE+A+ +    SF  +    +S      +HSLW    K+N      G + L+     W+ GL+KH  A+S L  P+ +C +R      +        W  ND  C   +K   EK T IEN+L S+ A PY  LAAT+AAG+DG+   N++   P  D+S         ++P   E+AL  LE+D  +++ALGE F+ YF+ +K+     E+      + E++ +ER ++ EY
Sbjct:   56 CMRDSSQILTPPQLSSRMKHIRQAMAKNRLQFVRFEATDLHGVSRSKTIPAHFFQEKVSHGVCMPRGYLEVIPNPKDNEMNNIRATCFNSDIVLMPELSTFRVLPWADRTAR------VICDTFTVTGEPLLTSPRYIAKRQLSHLQASGFSLLSAFIYDFCIFGVP--EILNSKIISFPALTFLNNHDQPFMQELVDGLYHTGANVESFSSSTRPGQMEISFLPEFGISSADNAFTLRTGVKEVARKYNYIASFFIETGFCDSGI---LSHSLWDVDRKKNMFCSTSGTEQLTITGKKWLAGLLKHSAALSCLMAPSVSCRKRYSKDRKDLKKSVPTTWGYNDNSCIFNIKCHGEKGTRIENKLGSATANPYLVLAATVAAGLDGLHSSNEVLAGP--DESTDFYQVEPSEIPLKLEDALVALEEDQCLRQALGETFIRYFVAMKK----YEL------ENEEIAAERNKFLEY 507
[Close]
BLAST of Gln-synt_C domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8CIX8|LGSN_MOUSE (Lengsin OS=Mus musculus OX=10090 GN=Lgsn PE=1 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 7.801e-50
Identity = 129/460 (28.04%), Postives = 220/460 (47.83%), Query Frame = 3 
Query:  489 RILKKMSNCKSQL--KDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENK-SRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMYKTTMLAKYEKFFM-DAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRL----HNFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDKSM-------GDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEY 1823
            ++  +M + K ++      F+R    DL+G   SK + +Q  Q    + V +  G + L P  +   ++       + +    P+L T + + WA+   R      VI D       P+   PR +A +Q+R+L++    L SAF  +F  F +      S  +    +T+L+ +++ FM + V  L   G +++        GQ+E+  LP FGI++AD AF  + G++E+A+ +    S + +     S      +HS+W    K N      G + L+     W+ GL+KH  A+S L  P  NC +R      +        W  ND  C++ +K   EK T IEN+L S+ A PY  LAAT+AAG+DG+ +        D+S         ++P   E+AL  LE+D+ +K+ALGE F+ YF+ +K+     E+      + E+ ++E  ++ EY
Sbjct:  122 QLSARMKHIKQEMAKNHLQFVRFEATDLHGVSRSKSIPAQFFQEKVIHGVFMPRGYLELMPNPKDNEVNHIRATCFNSDIVLMPELSTFRVLPWAERTAR------VICDTFTVTGEPLLTSPRYIAKRQLRQLQDAGFCLLSAFIYDFCIFGVPEV-INSKTISFPASTLLSNHDQPFMQELVEGLYQTGANVESFSSSTRPGQMEICFLPEFGISSADNAFTLRTGLQEVARRYNYIASLVIETGFCNSGI---LSHSIWDVGGKTNMFCSGSGVERLTLTGKKWLAGLLKHSAALSCLMAPAVNCRKRYCKDSRDLKDSVPTTWGYNDNSCALNIKCHGEKGTQIENKLGSATANPYLVLAATVAAGLDGLQSSDGAAAGSDESQDLYQPEPSEIPLKMEDALAALEQDECLKQALGETFIRYFVAMKK----YEL------ENEETDAEGNKFLEY 561
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BLAST of Gln-synt_C domain-containing protein vs. UniProt/SwissProt
Match: sp|Q0GA40|LGSN_RABIT (Lengsin OS=Oryctolagus cuniculus OX=9986 GN=LGSN PE=2 SV=1)

HSP 1 Score: 184.496 bits (467), Expect = 2.460e-49
Identity = 130/472 (27.54%), Postives = 222/472 (47.03%), Query Frame = 3 
Query:  453 CYVNGIQII*HLRILKKMSNCKSQL--KDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENKSRN-AYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMYKTTMLAKYEKFFM-DAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRR----LHNFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDKSM-------GDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEY 1823
            C  +  QI+   ++  +M + K ++      F++    DL+G   SK + +   Q    + V +  G + L P  +   ++        N     P+L T + + WA+   R      VI D       P+   PR +A +Q+ +L++    L SAF  +F  F +      S  +    +T++  +++ FM + V  L   G  ++        GQ+E+  LP FGI++AD AF  + G+KE+A+ +    SF  +     S      +HSLW    K+N   +  G + L+ +   W+ GL+KH  A+S L  P  +C +R      +        W  ND  C+  +K   +K   IEN+L S+ A PY  LAAT+AAG+DG+ + +      D S         ++P   E+AL  LE+D+ ++EALGE F+ YF+ +K+     E+      + E+ ++ER ++ EY
Sbjct:  118 CTRDSTQILTPPQLSSRMKHIKQEMAKNHLQFVQFEASDLHGVSRSKSIPAHFFQEKVIHGVFMPRGYLELIPNPKDNEVNHIRATCFNNDIVLMPELSTFRVLPWAERTAR------VICDTFTVTGEPLLTSPRYIAKRQLNQLQDCGFSLLSAFIYDFCIFGVPEI-INSKTISFAASTLVNNHDQPFMQELVDGLYHTGASVESFSSSTRPGQMEICFLPEFGISSADNAFTLRTGVKEVARKYNYIASFFIETGFCNSGI---LSHSLWDVDGKKNMFCNSSGVEQLTIIGKKWLAGLLKHSAALSCLMAPAVSCRKRYSKETKDLKESVPTTWGYNDNSCAFNIKCHGDKGARIENKLGSATANPYLVLAATVAAGLDGLQSNLDDLAGPDDSTDLFQSEPSEIPLKLEDALVALEEDECLREALGETFIRYFVAMKK----YEL------ENEETDAERNKFLEY 569
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BLAST of Gln-synt_C domain-containing protein vs. UniProt/SwissProt
Match: sp|Q1ZZS1|LGSN_CANLF (Lengsin OS=Canis lupus familiaris OX=9615 GN=LGSN PE=2 SV=1)

HSP 1 Score: 184.111 bits (466), Expect = 3.215e-49
Identity = 131/457 (28.67%), Postives = 216/457 (47.26%), Query Frame = 3 
Query:  501 KMSNCKSQL--KDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENK-SRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMYKTTMLAKYEK-FFMDAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLH----NFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNK--IYPPPKGDKS------MGDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEY 1823
            +M + K ++      F+R    DL+G   SK + +   Q    + V +  G + L P  +   +D       + +    P+L T + + WA+   R      VI D       P+   PR +A +Q+ +L++    L SAF  +F  F +      S  +    +T+L  +++ F  + V  L   G +++        GQ+E+  LP FGI++AD AF  + G+KE+A+ +    SF  +     S      +HSLW    K+N      G + L+     W+ GL+KH  A+S L  P  +C +R      +        W  ND  C+  +K   EK T IEN+L S+ A PY  LAAT+AAG+DG+ +   +   P GD +        ++P   E+AL  LE+D  +++ALGE F+ YF+ +K+  DL         + E+ ++ER ++ EY
Sbjct:  137 RMKHIKQEMAKNHLQFVRFEATDLHGVSRSKSIPAHFFQEKVIHGVCMPRGYLELIPNPKDDEVDHIRATCFNSDIVLMPELSTFRVLPWAERTAR------VICDTFTVTGEPLLTSPRYIAKRQLSQLQDSGFSLLSAFIYDFCIFAVPEI-INSKTISFPASTLLNNHDQPFIQELVDGLYHTGANVESFSSSTRPGQMEICFLPEFGISSADNAFTLRTGVKEVARKYNYIASFFIETGFCNSGI---LSHSLWDVDGKKNMFCSSSGIEELTITGKKWLAGLLKHSAALSCLMAPAVSCRKRYSKESKDLKESVPTTWGYNDNSCAFNIKCHGEKGTRIENKLGSATANPYLVLAATVAAGLDGLQSSDGVLASP-GDSTDLYPSKPSEIPLKLEDALVALEEDQCLRQALGETFIRYFVAMKK-YDL---------ENEETDAERNKFLEY 572
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BLAST of Gln-synt_C domain-containing protein vs. TrEMBL
Match: A0A4E0R2L8 (Glutamine synthetase OS=Fasciola hepatica OX=6192 GN=D915_006866 PE=3 SV=1)

HSP 1 Score: 436.802 bits (1122), Expect = 7.555e-144
Identity = 220/481 (45.74%), Postives = 301/481 (62.58%), Query Frame = 3 
Query:  498 KKMSNCKSQLKDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENKSRNAYFFPDLDTLKPIKWADDLERDF------KVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMD-LELFSAFEPEFRAFKLDSYE---------------------PFSSGLDMYKTTMLAKYEKFFMDAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLHNFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDKSMGD--------LPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKL--NDQEQLESERKQYFEYI 1826
            KK +  ++ L+ FD++R+   DLNG H+SKLVS++ A++I + + ++Y G I  GPRT+ V + +  E K  NA   PDL TL    WA  L ++       +VG V+ D+ W E  P+E +PR+VA + ++ LEE   L L+SAFEPEFRAFKL+S E                     PF++G D YKT +LA+YE FFMD   K+   GID+QD   E+G GQLE PL+P  G+ AAD  F FKQ +KE+   H + ISFMT PF   +SSG H+NHSLW   +  NA +D +  DNLS +AL+W+GGL+ HLPAI ALC PT NCYRRLH  +AP ++NWDINDRF ++RVKN +EK TYIE+R+PSSA+CPYH +AATIAAG+DG+  ++ PP  G K +          LP + +EA+  L  D  + + LGE+FV++FI+ K   D+  +    +  N    L  ER +Y  YI
Sbjct:   10 KKQTGTRNSLESFDYVRLCIVDLNGIHLSKLVSTKFAKKITDGDCEVYSGIITFGPRTEVVDVPKVVERKHVNARLRPDLTTLHSCPWAGQLHKNISQTMEPRVGAVLCDLYWPEGDPLEAYPRVVARRLLKELEERHKLYLYSAFEPEFRAFKLESMERSCANPAQSREEKSIPPADPEPFTTGEDFYKTGLLAQYESFFMDVDMKIREIGIDVQDYSNENGAGQLECPLVPKTGLQAADHYFIFKQALKEIGLQHNIGISFMTTPFTEGTSSGCHYNHSLWNTVSGSNAFYDPQNPDNLSTVALHWLGGLMTHLPAILALCSPTVNCYRRLHRKLAPDAVNWDINDRFVAVRVKNVDEKRTYIESRIPSSASCPYHVMAATIAAGMDGLERQLLPPSPGQKPIDGRATETCKLLPHSLQEAIAGLRADTTLVKRLGEEFVDWFIQGKERGDIKSLAHSDITKNSGWDLAHERNEYLSYI 490
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BLAST of Gln-synt_C domain-containing protein vs. TrEMBL
Match: A0A504YZA2 (Glutamine synthetase OS=Fasciola gigantica OX=46835 GN=FGIG_06082 PE=3 SV=1)

HSP 1 Score: 436.417 bits (1121), Expect = 8.238e-144
Identity = 220/481 (45.74%), Postives = 301/481 (62.58%), Query Frame = 3 
Query:  498 KKMSNCKSQLKDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENKSRNAYFFPDLDTLKPIKWADDLERDF------KVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMD-LELFSAFEPEFRAFKLDSYE---------------------PFSSGLDMYKTTMLAKYEKFFMDAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLHNFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDKSMGD--------LPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKL--NDQEQLESERKQYFEYI 1826
            KK +  ++ L+ FD++R+   DLNG H+SKLVS++ A++I + + ++Y G I  GPRT+ V + +  E K  NA   PDL TL    WA  L ++       +VG V+ D+ W E  P+E +PRIVA + ++ LEE   L L+SAFEPEFRAFKL+S E                     PF++G D YKT +LA+YE FFMD   K+   GID+QD   E+G GQLE PL+P  G+ AAD  F FKQ +KE+   H + +SFMT PF   +SSG H+NHSLW   +  NA +D +  DNLS +AL+W+GGL+ HLPAI ALC PT NCYRRLH  +AP ++NWDINDRF ++RVKN +EK TYIE+R+PSSA+CPYH +AATIAAG+DG+  ++ PP  G K +          LP + +EA+  L  D  + + LGE+FV++FI+ K   D+  +    +  N    L  ER +Y  YI
Sbjct:   10 KKQTGTRNSLESFDYVRLCIVDLNGIHLSKLVSTKFAKKITDGDCEVYSGIITFGPRTEVVDVPKVVERKHVNARLRPDLTTLHSCPWAGQLHKNINQTMEPRVGAVLCDLYWPEGDPLEAYPRIVARRLLKELEERHKLYLYSAFEPEFRAFKLESMERSCANPAQPREEKSIPPADPEPFTTGEDFYKTGLLAQYESFFMDVDMKIREIGIDVQDYSNENGAGQLECPLVPKTGLQAADHYFIFKQALKEIGLQHNIGVSFMTTPFTEGTSSGCHYNHSLWNTVSGSNAFYDPQNPDNLSTVALHWLGGLMTHLPAILALCSPTVNCYRRLHRKLAPDAVNWDINDRFVAVRVKNVDEKRTYIESRIPSSASCPYHVMAATIAAGMDGLERQLLPPSPGQKPIDGQATETCKLLPHSLQEAIAGLRADTTLVKRLGEEFVDWFIQGKERGDIKSLAHSDITKNSGWDLAHERNEYLSYI 490
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BLAST of Gln-synt_C domain-containing protein vs. TrEMBL
Match: A0A3Q0KD81 (Glutamine synthetase bacteria, putative OS=Schistosoma mansoni OX=6183 PE=3 SV=1)

HSP 1 Score: 424.861 bits (1091), Expect = 7.387e-139
Identity = 216/482 (44.81%), Postives = 299/482 (62.03%), Query Frame = 3 
Query:  525 LKDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENKSRNAYFFPDLDTLKPIKWADDL-----ERDFKV------------GDVIADMKWDETSPVEFHPRIVAAKQIRRLEE-MDLELFSAFEPEFRAFKLDSYE---------------------PFSSGLDMYKTTMLAKYEKFFMDAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLHNFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDKSMGD-------LPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLND--QEQLESERKQYFEYI 1826
            ++ +DFIR+S PD+NG H+SKL+ ++ A+++   +V++Y G+IA GPR + V I E  E K  N+   PD  TL P  W         ++D K+              V+ D+ W    PV  +PR VA + I+ LE+  +L L+SAFEPEFRAF   SYE                     P+++  DMY+T++L+ YE +F D    + +AGIDIQD   E GEGQLE PL+P++G++AAD  F  KQ +KE+   H M ISFMT P L  SSSG H+NHSLWY +  RNA +D K  D LS LA +WIGG+++HLPA+ A+ CPT NCYRRLH  +AP  +NWD +DR+ SIRVKN NEK TYIENR+PSSA+C YH LAATIAAG+DG+  +IYPPP G K   D       LP+  ++AL  L  D ++   LG  FV+++I++K++ DL  +    ++D  +E L  ER +YF ++
Sbjct:   32 VEKYDFIRLSLPDINGIHLSKLLPTRFAKKLAMGQVEIYSGSIAFGPRFEMVSIPEVVEKKHINSVLKPDFSTLHPCHWISQKNYPHPQKDNKMVLNAEEGGKYSFCSVLCDVYWPNNQPVYAYPRFVAQRLIKELEDKYNLRLYSAFEPEFRAFVKGSYETSCLEPKSEDVTQFIDLKKPIPWTNFRDMYRTSLLSVYENYFADIDYNMQLAGIDIQDYSNEDGEGQLECPLIPTWGLSAADNYFILKQAVKEIGSKHGMEISFMTTPLLDSSSSGCHYNHSLWYANNNRNAFYDDKDPDRLSTLARHWIGGILEHLPAMLAISCPTVNCYRRLHKHLAPSCVNWDFHDRYISIRVKNLNEKQTYIENRIPSSASCSYHVLAATIAAGLDGLERQIYPPPSGLKLENDKTGVCKVLPNTIQQALRSLTDDKILVNKLGADFVDWYIQVKKNGDLSSLGHLNIHDNTEETLAYERYEYFNFM 513
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BLAST of Gln-synt_C domain-containing protein vs. TrEMBL
Match: A0A183AAU1 (Gln-synt_C domain-containing protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS4076 PE=3 SV=1)

HSP 1 Score: 424.861 bits (1091), Expect = 7.629e-139
Identity = 219/481 (45.53%), Postives = 292/481 (60.71%), Query Frame = 3 
Query:  516 KSQLKDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENKSRNAYFFPDLDTLKPIKWADDLERD-----------FKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEE-MDLELFSAFEPEFRAFKLDSYEP---------------------FSSGLDMYKTTMLAKYEKFFMDAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLHNFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDKSMGD--------LPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGK---KLNDQEQLESERKQYFEYI 1826
            +SQL  +DF+R+   DLNG H+SKLVS++ A++I + + ++Y G I  GPR + V + +  E K  N +  PD  TL P  WA  L R+           +KV  V+ DM W E   ++ HPR+V  + ++ LEE   L L+SAFEPEFRAFK+++  P                     F+ G DMYKT++LA+YE FFMD  T++   GI++QD   E+G GQLE PL+P  G+ AAD  F  KQ +KE+   H M +SFMT PF   +SSG H+NHSLW   T  NA +D K  DNLS +A +WIGGL+ HLPAI A C PT NCYRRLH  +AP ++NWDINDRF ++RVKN +EK TYIENR+PSSA+C YH +AATIAAG+DG+  K+ PP  G K +          LP   +EAL  L  D+ + + LGE+FV++F++ K   DL    GK     N    L  ER +Y  YI
Sbjct:   36 QSQLATYDFVRLCFVDLNGIHLSKLVSTKYAKKIIDGQCEMYAGMITFGPRMEVVDVPKVVERKHVNGHLHPDFSTLHPCPWAGSLNRNISYPNPEAAPTYKVCAVLCDMHWPEGDAMQAHPRVVVKRLLQELEEKHKLTLYSAFEPEFRAFKVETMAPSCANPNSSTTPLEDPPADPVPFTLGEDMYKTSLLAEYESFFMDVDTRVREIGIEVQDYSNENGAGQLECPLIPKVGLQAADHYFILKQILKEIGLQHNMGVSFMTTPFQEGTSSGCHYNHSLWNVETGTNAFYDAKSPDNLSKVAHHWIGGLMAHLPAILAFCSPTVNCYRRLHKKLAPDAVNWDINDRFVAVRVKNTDEKRTYIENRIPSSASCSYHVMAATIAAGMDGIERKLEPPAPGQKPVDRKATATCKLLPHTLQEALTELRADEPLVKRLGEEFVDWFVQNKERGDL-HTLGKVDVGKNSGWDLAFERNEYLFYI 515
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BLAST of Gln-synt_C domain-containing protein vs. TrEMBL
Match: A0A3Q0KM88 (Putative glutamine synthetase bacteria OS=Schistosoma mansoni OX=6183 PE=3 SV=1)

HSP 1 Score: 423.32 bits (1087), Expect = 1.852e-138
Identity = 216/483 (44.72%), Postives = 301/483 (62.32%), Query Frame = 3 
Query:  522 QLKDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENKSRNAYFFPDLDTLKPIKW---------------ADDLERD--FKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLE-EMDLELFSAFEPEFRAFKLDSYE---------------------PFSSGLDMYKTTMLAKYEKFFMDAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLHNFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDK--------SMGDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKR--DVDLIEIFGKKLNDQEQLESERKQYFEY 1823
            +++ FD+IR+S PDLNG H+SKL+S+Q A++I   E ++Y GAI  GPR +   + E  + K  N+   PD  TL P  W               +DD  R+  + +  V+ D+ W    P++ HPR+   K I  L+ + +L LFSAFEPEFRAF+  ++E                     P++   D+Y+T++L+ YE FF+D    + +A IDIQD   E GEGQLE PL+PS+G++AAD  F  KQ IKE+ K H M ISFMTKP L+ SSSG H+NHSLWY  T RNA +D    D LS  A +WIGGLI+HLPA+ A+C PT NCYRRL+ F APG++NWD +DRF ++RVKNF+EKNTYIENR+PSSA+CPYH LAAT+AAG+DG+  ++ PPP G K         +  LPS+ +EAL  L++D++  + LG+ F  ++  +K   D+  +     K N +E L  ER +Y ++
Sbjct:   24 EVEKFDYIRLSFPDLNGIHLSKLLSTQFARKIAKGESEVYSGAITGGPRGEVFDVTEIIKRKHVNSKLKPDFSTLHPCHWISNGKAQHSHNNNTDSDDNRRNRKYSICAVLCDLAWPNDEPMKAHPRVAVKKLIDELQTKYNLRLFSAFEPEFRAFEKGTFETTCLKPTKTRETNLCSFKLPVPYTKFCDIYRTSLLSVYEDFFIDIDHNMKLANIDIQDYSNEDGEGQLESPLVPSWGLSAADNYFILKQAIKEIGKKHDMEISFMTKPLLNASSSGCHYNHSLWYADTGRNAFYDNTDPDGLSVTARHWIGGLIEHLPAMLAICSPTTNCYRRLNKFFAPGAVNWDFHDRFVAVRVKNFDEKNTYIENRIPSSASCPYHVLAATLAAGLDGLDRQLEPPPPGQKPSESKIENQVKMLPSSLQEALQSLKEDEIFTKKLGKDFFEWYTLVKELGDLGALGHLNIKDNQEETLAFERYEYLKF 506
[Close]
BLAST of Gln-synt_C domain-containing protein vs. Ensembl Cavefish
Match: lgsn (lengsin, lens protein with glutamine synthetase domain [Source:NCBI gene;Acc:103040170])

HSP 1 Score: 186.422 bits (472), Expect = 2.908e-50
Identity = 137/450 (30.44%), Postives = 214/450 (47.56%), Query Frame = 3 
Query:  528 KDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGA-------IALGPRTQYVGIDEFTENKSRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMY-KTTMLAKYE-KFFMDAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRL---HNFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIY------PPPKGDKSMGDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEY 1823
            ++  F+R    DL+G   SK+V ++       +E  +YG         + L P+   V       N S +    PDL T + + W++   R      VI D       P+   PR++A   + +L+ M   L S+F   +    L + E     +  +  TT+L+ ++  F    V  +   G D+ +     G GQ+E+   P FGI AAD AF F+ GIKE+A+ H   ++F+T   L+        +HSLW  + +++      GE  LSD+   W+GGL+ H PA+S L  P   C  +L    +   P       ND  CS  VK    +  +I+NRL S+ A PY  LAATIAAG+DG+   +         P   K +  +P   E+AL  L +D VI+ +LGE F+ YFI +KR    +EI      + ++L+++R +  EY
Sbjct:  250 ENVGFVRFEATDLHGVSRSKMVPARYF-----HEKAVYGVPMPRSYLELTLSPKDNEVD-HPSAANFSSDVLLVPDLSTFRVLPWSEQTAR------VICDPCTVTGVPLRTSPRLIAKLMLGQLQSMGFSLHSSFT--YECCILGAPERLGPKVVFFPATTLLSNHDLPFLQQLVRAMYHMGADVDNFASASGPGQMEICFKPKFGIEAADSAFTFRTGIKEMARKHNYIVTFLTDETLNNL---GQLSHSLWDANGRKSLFHSSTGE--LSDIGKKWLGGLLHHSPALSCLLAPGIGCRSQLSKGRDSKHPLYATCGCNDNSCSFNVKIHGGREMHIDNRLGSAMANPYIVLAATIAAGLDGIKRNLSIEQGLNRAPNQQKQV-VIPVKLEDALEALAEDAVIRGSLGEPFIQYFIAMKR----LEI------ETQELDTDRNKGLEY 669
[Close]
BLAST of Gln-synt_C domain-containing protein vs. Ensembl Cavefish
Match: lgsn (lengsin, lens protein with glutamine synthetase domain [Source:NCBI gene;Acc:103040170])

HSP 1 Score: 186.037 bits (471), Expect = 5.648e-50
Identity = 137/450 (30.44%), Postives = 214/450 (47.56%), Query Frame = 3 
Query:  528 KDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGA-------IALGPRTQYVGIDEFTENKSRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMY-KTTMLAKYE-KFFMDAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRL---HNFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIY------PPPKGDKSMGDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEY 1823
            ++  F+R    DL+G   SK+V ++       +E  +YG         + L P+   V       N S +    PDL T + + W++   R      VI D       P+   PR++A   + +L+ M   L S+F   +    L + E     +  +  TT+L+ ++  F    V  +   G D+ +     G GQ+E+   P FGI AAD AF F+ GIKE+A+ H   ++F+T   L+        +HSLW  + +++      GE  LSD+   W+GGL+ H PA+S L  P   C  +L    +   P       ND  CS  VK    +  +I+NRL S+ A PY  LAATIAAG+DG+   +         P   K +  +P   E+AL  L +D VI+ +LGE F+ YFI +KR    +EI      + ++L+++R +  EY
Sbjct:  284 ENVGFVRFEATDLHGVSRSKMVPARYF-----HEKAVYGVPMPRSYLELTLSPKDNEVD-HPSAANFSSDVLLVPDLSTFRVLPWSEQTAR------VICDPCTVTGVPLRTSPRLIAKLMLGQLQSMGFSLHSSFT--YECCILGAPERLGPKVVFFPATTLLSNHDLPFLQQLVRAMYHMGADVDNFASASGPGQMEICFKPKFGIEAADSAFTFRTGIKEMARKHNYIVTFLTDETLNNL---GQLSHSLWDANGRKSLFHSSTGE--LSDIGKKWLGGLLHHSPALSCLLAPGIGCRSQLSKGRDSKHPLYATCGCNDNSCSFNVKIHGGREMHIDNRLGSAMANPYIVLAATIAAGLDGIKRNLSIEQGLNRAPNQQKQV-VIPVKLEDALEALAEDAVIRGSLGEPFIQYFIAMKR----LEI------ETQELDTDRNKGLEY 703
[Close]
BLAST of Gln-synt_C domain-containing protein vs. Ensembl Nematostella
Match: EDO25869 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TDH3])

HSP 1 Score: 100.138 bits (248), Expect = 2.709e-23
Identity = 83/299 (27.76%), Postives = 130/299 (43.48%), Query Frame = 3 
Query:  720 YFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVE-FHPRIVAAKQIRRLEEMDLELFSAFEPEF--------------RAFKLDSYEPFSSGLDMYKTTMLAKYEKFFMDAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSF-GIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLH-NFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATI 1565
            Y  P   TL+P  W     R    G +   M   +  P     PR V  + I RL+        A E EF               A + +   P +    +Y    L + + F  D  +   V G+ ++    E+  GQ+E+ L   F  + A D+  R+K+ +K +A  H M   FM KPF  ++ SG H + SL   + +         + + + L  + IGG++  L    A+ CP AN YRR   N  AP + +W +N+R  S RV     K+ ++E+R+  + A PY A AA +
Sbjct:   10 YPIPGSLTLQP--W-----RSTPTGQLQVSMHPTQGLPAAPADPRHVLVRAIDRLKADGYHPVMAVELEFYLLDKNRDANGRPQPALQANGVRPQAP--QVYGVYELEQLQPFLDDLYSACEVQGLPVRTAISEYAPGQVELTLEHRFDALQAVDEGVRYKRLVKGVANKHGMQACFMAKPFGDQAGSGMHMHVSL---ADEHGNNLMASEDPHGTPLLKHAIGGMMATLNDALAIFCPNANSYRRFQANSYAPLAKSWGVNNRTVSFRVPGGPAKSRHVEHRICGADANPYLAAAAIL 296
[Close]
BLAST of Gln-synt_C domain-containing protein vs. Ensembl Medaka
Match: lgsn (lengsin, lens protein with glutamine synthetase domain [Source:NCBI gene;Acc:101162898])

HSP 1 Score: 184.111 bits (466), Expect = 1.124e-49
Identity = 142/464 (30.60%), Postives = 219/464 (47.20%), Query Frame = 3 
Query:  495 LKKMSNCKSQL--KDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGA-------IALGPRTQYVGIDEFTENKSRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMY-KTTMLAKYE-KFFMDAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLHNFIA-PGSLNW---DINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDG------VVNKIYPPPKGDKSMGDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEY 1823
            +  M   K Q+  ++ +F+R    DL+G   SK V  +       +E  +YG         + L P++  V     T N S +    PDL T K + WA+   R      VI D      SP+   PR++A + + +L+ +   L S+F   +    L + E       ++  TT+L+ ++  FF   V  +   G DI       G GQ+E+ L P FGI+AAD AF F+ GIKE+A+      SF T   L  +      +HSLW  + +R+     +    LS++   W+ GL+ H  A+S L  P   C   +   I  P  L +     ND   S  +K+   + T+++N+L S+ A PY  LAAT+AAG+DG      V + +   P   K    +P   ++AL  LE+D VI+ ALGE FV YFI +K+     EI      + ++L+ ER +  EY
Sbjct:  199 MASMEQIKQQIARENINFVRFEATDLHGVSRSKTVPVR-----HFHEKAVYGVPMPRSYLELTLSPKSNEVD-HASTANFSSDVLLIPDLSTFKLLPWAEQTAR------VICDPCTVTGSPLWTSPRLIAKQLLGQLQSLGFSLHSSFT--YECCVLGAPERIGPKTLLFPATTLLSNHDLPFFQQLVDSMYCMGADIDSIASASGPGQMEINLRPEFGISAADSAFTFRTGIKEMARKLSYIASFFTDDGLYNAGV---LSHSLWDANGRRSLFHGGEKPGELSEIGRKWLAGLLTHSAALSCLMSPGLGCRNHMAKTIKDPKRLLYATCGCNDNSSSFNIKSHGGRETHVDNKLGSAMANPYIVLAATVAAGLDGIRRNLTVESSLTKAPSQQKDF-SIPIKMDDALEALEEDHVIRSALGEPFVQYFIAMKK----FEI------ETQELDDERNKCLEY 634
[Close]
BLAST of Gln-synt_C domain-containing protein vs. Planmine SMEST
Match: SMESG000064881.1 (SMESG000064881.1)

HSP 1 Score: 918.687 bits (2373), Expect = 0.000e+0
Identity = 441/441 (100.00%), Postives = 441/441 (100.00%), Query Frame = 3 
Query:  504 MSNCKSQLKDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENKSRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMYKTTMLAKYEKFFMDAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLHNFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDKSMGDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEYI 1826
            MSNCKSQLKDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENKSRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMYKTTMLAKYEKFFMDAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLHNFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDKSMGDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEYI
Sbjct:    1 MSNCKSQLKDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENKSRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMYKTTMLAKYEKFFMDAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLHNFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDKSMGDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEYI 441
[Close]
BLAST of Gln-synt_C domain-containing protein vs. Planmine SMEST
Match: SMESG000064881.1 (SMESG000064881.1)

HSP 1 Score: 877.856 bits (2267), Expect = 0.000e+0
Identity = 426/441 (96.60%), Postives = 427/441 (96.83%), Query Frame = 3 
Query:  504 MSNCKSQLKDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENKSRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMYKTTMLAKYEKFFMDAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLHNFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDKSMGDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEYI 1826
            MSNCKSQLKDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENKSRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMYKTTMLAKYEKFFMDAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLHNFIAPGSLNWDINDRFC              +NRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDKSMGDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEYI
Sbjct:    1 MSNCKSQLKDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYVGIDEFTENKSRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMYKTTMLAKYEKFFMDAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLHNFIAPGSLNWDINDRFC--------------KNRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDKSMGDLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEYI 427
[Close]
BLAST of Gln-synt_C domain-containing protein vs. Planmine SMEST
Match: SMESG000003831.1 (SMESG000003831.1)

HSP 1 Score: 236.498 bits (602), Expect = 1.147e-70
Identity = 148/453 (32.67%), Postives = 238/453 (52.54%), Query Frame = 3 
Query:  483 HLRILKKMSNCKSQLKDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYV-GIDEFTENKSRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMYKTTMLAKYEKFFMDAVTKLAVA-GIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTK--RNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLHNF-IAPGSLNWDINDRFCSIRVK--NFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDKSMGD-LPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYF 1817
            +L + + MSN      + +FI+  T D++G    K+   +    +  N+ ++ G    LG R +    + E +EN  RN    P+  +L+   W+ D        D    +     SP  F+PR++A  +I+ LE M ++L    E EFR F   S +P +  + +      A     F   + K+A    I+     +E+G GQ+E+PL    GI   DK + F++  K +A    +  ++MT P   E+++G H NHSLW    K   N  +D K E++LSD+  +W+ G++KH  A+SA   PT NCYRR+     AP +++W+ +DR  ++RVK    NEK  YIENRLPSSA   Y A+A+ I AGIDG+ NK+     G+    + LP    E+L +L++D V+ E LG KFV++++K+K++ ++       ++D    E E  +YF
Sbjct:    5 YLYLFRIMSNHTKLPDEVEFIQTITVDIHGFSRGKMFPREKLNDLFQNKEEVVGLLEVLGTRFEIPESLTELSENHYRNILITPEKSSLRVAPWSKDSSLAMVFYDAYDKIT---NSPWPFNPRLLAKNKIKELEVMGMKLMIGVENEFRLFGKGSRKPLTDSVQLLSQFHQATVVLPFARELKKVAKDFDIEFDSWNLEYGSGQIEIPLRAYEGINGVDKVWMFRETSKYVADRLNLHATYMTLPISKETANGMHINHSLWSVKDKGLSNLFWDSKNENSLSDVGKHWLAGILKHTRALSAFFSPTVNCYRRVAAADWAPNNISWNYDDRSVAMRVKTSTANEKQNYIENRLPSSACNIYIAIASMIVAGIDGIKNKLDLFEAGNGFHCEKLPKTLAESLEVLKQDKVLTEGLGPKFVDWYVKVKQETEVDLFKSVNIHDVGLTELEFHKYF 454
[Close]
BLAST of Gln-synt_C domain-containing protein vs. Planmine SMEST
Match: SMESG000003836.1 (SMESG000003836.1)

HSP 1 Score: 234.958 bits (598), Expect = 4.366e-70
Identity = 152/443 (34.31%), Postives = 229/443 (51.69%), Query Frame = 3 
Query:  528 KDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQY-VGIDEFTENKSRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGL----DMYKTTMLAKYEKFFMDAVTKLAVAGIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTKR--NAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRR-LHNFIAPGSLNWDINDRFCSIRVK--NFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDKSMG-DLPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQ--EQLESERKQYF 1817
            K+ +FI+  T D+NG    K+   +    +   + ++ G    LG +++    I E T N   N    PD  +++   W+DD        D    +K     P  F+PR+ A KQ+  LE+M  + F   E EFR F   + +PF+  +       ++T    Y K     + ++    I++    +E+G GQ+E+PL    G+   D A+ FK+  K +A    M  S+M  P   ++ +G H NHSLW K+ +   NAM+    +D +S++A +W+ GL+KH  A+ A   PT NCYRR L    AP  ++W+  DR  + RVK  +  EK  YIENRLPSSA   Y A+A  I AGIDG+ NKI  P   +   G DLP +  EAL+ L KD V+   +GEKF+++FIK K + D+  +    L  Q  E L+ E  +YF
Sbjct:   12 KNVEFIQAITVDINGIARGKVYPVEKLSDLLEGKQEVVGLLEILGTKSEIPQTISELTRNHFENELLVPDQTSIRGCPWSDDSSLAMFFYDTYDRVK---NVPWPFNPRLAARKQLNELEKMGFKFFIGVENEFRLFDKHTRKPFTQEICFDHQFTQSTTALPYMKGLCKILKRM---NIEMDSWHLEYGLGQIEVPLKVYSGMEGVDNAWFFKELSKYVANDFGMIASYMCVPLARDAGNGLHINHSLWIKTNESFTNAMWAKSDKDEMSEIAQHWLAGLLKHSKALCAFFNPTVNCYRRILMANWAPNKISWNYRDRTVAFRVKASSNQEKVNYIENRLPSSACNIYLAIAGMIVAGIDGIKNKIKLPDPANIFHGEDLPRSLPEALDELSKDQVLINGMGEKFIDWFIKAKLETDVFVLRNVDLESQTEEALQQEFDKYF 448
[Close]
BLAST of Gln-synt_C domain-containing protein vs. Planmine SMEST
Match: SMESG000003831.1 (SMESG000003831.1)

HSP 1 Score: 234.572 bits (597), Expect = 4.672e-70
Identity = 147/446 (32.96%), Postives = 234/446 (52.47%), Query Frame = 3 
Query:  504 MSNCKSQLKDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAIALGPRTQYV-GIDEFTENKSRNAYFFPDLDTLKPIKWADDLERDFKVGDVIADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYEPFSSGLDMYKTTMLAKYEKFFMDAVTKLAVA-GIDIQDCCIEHGEGQLEMPLLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNHSLWYKSTK--RNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCYRRLHNF-IAPGSLNWDINDRFCSIRVK--NFNEKNTYIENRLPSSAACPYHALAATIAAGIDGVVNKIYPPPKGDKSMGD-LPSNFEEALNILEKDDVIKEALGEKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYF 1817
            MSN      + +FI+  T D++G    K+   +    +  N+ ++ G    LG R +    + E +EN  RN    P+  +L+   W+ D        D    +     SP  F+PR++A  +I+ LE M ++L    E EFR F   S +P +  + +      A     F   + K+A    I+     +E+G GQ+E+PL    GI   DK + F++  K +A    +  ++MT P   E+++G H NHSLW    K   N  +D K E++LSD+  +W+ G++KH  A+SA   PT NCYRR+     AP +++W+ +DR  ++RVK    NEK  YIENRLPSSA   Y A+A+ I AGIDG+ NK+     G+    + LP    E+L +L++D V+ E LG KFV++++K+K++ ++       ++D    E E  +YF
Sbjct:    1 MSNHTKLPDEVEFIQTITVDIHGFSRGKMFPREKLNDLFQNKEEVVGLLEVLGTRFEIPESLTELSENHYRNILITPEKSSLRVAPWSKDSSLAMVFYDAYDKIT---NSPWPFNPRLLAKNKIKELEVMGMKLMIGVENEFRLFGKGSRKPLTDSVQLLSQFHQATVVLPFARELKKVAKDFDIEFDSWNLEYGSGQIEIPLRAYEGINGVDKVWMFRETSKYVADRLNLHATYMTLPISKETANGMHINHSLWSVKDKGLSNLFWDSKNENSLSDVGKHWLAGILKHTRALSAFFSPTVNCYRRVAAADWAPNNISWNYDDRSVAMRVKTSTANEKQNYIENRLPSSACNIYIAIASMIVAGIDGIKNKLDLFEAGNGFHCEKLPKTLAESLEVLKQDKVLTEGLGPKFVDWYVKVKQETEVDLFKSVNIHDVGLTELEFHKYF 443
The following BLAST results are available for this feature:
BLAST of Gln-synt_C domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
LGSN6.901e-5128.21lengsin, lens protein with glutamine synthetase do... [more]
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BLAST of Gln-synt_C domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Gln-synt_C domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Gln-synt_C domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
lgsn8.178e-4329.31lengsin, lens protein with glutamine synthetase do... [more]
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BLAST of Gln-synt_C domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pkn29.886e-4628.38protein kinase N2 [Source:Xenbase;Acc:XB-GENE-9952... [more]
avpr1b1.430e-4428.23arginine vasopressin receptor 1B [Source:Xenbase;A... [more]
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BLAST of Gln-synt_C domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Lgsn1.115e-5028.04lengsin, lens protein with glutamine synthetase do... [more]
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BLAST of Gln-synt_C domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q7TT51|LGSN_RAT3.806e-5228.48Lengsin OS=Rattus norvegicus OX=10116 GN=Lgsn PE=2... [more]
sp|Q5TDP6|LGSN_HUMAN3.314e-5028.21Lengsin OS=Homo sapiens OX=9606 GN=LGSN PE=1 SV=1[more]
sp|Q8CIX8|LGSN_MOUSE7.801e-5028.04Lengsin OS=Mus musculus OX=10090 GN=Lgsn PE=1 SV=1[more]
sp|Q0GA40|LGSN_RABIT2.460e-4927.54Lengsin OS=Oryctolagus cuniculus OX=9986 GN=LGSN P... [more]
sp|Q1ZZS1|LGSN_CANLF3.215e-4928.67Lengsin OS=Canis lupus familiaris OX=9615 GN=LGSN ... [more]
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BLAST of Gln-synt_C domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4E0R2L87.555e-14445.74Glutamine synthetase OS=Fasciola hepatica OX=6192 ... [more]
A0A504YZA28.238e-14445.74Glutamine synthetase OS=Fasciola gigantica OX=4683... [more]
A0A3Q0KD817.387e-13944.81Glutamine synthetase bacteria, putative OS=Schisto... [more]
A0A183AAU17.629e-13945.53Gln-synt_C domain-containing protein OS=Echinostom... [more]
A0A3Q0KM881.852e-13844.72Putative glutamine synthetase bacteria OS=Schistos... [more]
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BLAST of Gln-synt_C domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
lgsn2.908e-5030.44lengsin, lens protein with glutamine synthetase do... [more]
lgsn5.648e-5030.44lengsin, lens protein with glutamine synthetase do... [more]
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BLAST of Gln-synt_C domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Gln-synt_C domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Gln-synt_C domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO258692.709e-2327.76Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Gln-synt_C domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
lgsn1.124e-4930.60lengsin, lens protein with glutamine synthetase do... [more]
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BLAST of Gln-synt_C domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000064881.10.000e+0100.00SMESG000064881.1[more]
SMESG000064881.10.000e+096.60SMESG000064881.1[more]
SMESG000003831.11.147e-7032.67SMESG000003831.1[more]
SMESG000003836.14.366e-7034.31SMESG000003836.1[more]
SMESG000003831.14.672e-7032.96SMESG000003831.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010540 ID=SMED30010540|Name=Gln-synt_C domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1931bp
AAAAAATTCCACAATAAAATCGAGTGTTTCAAAATGAAGTAATGTAGATT
TATTCAAATTTCTGCTTGCAAATAAATTATACACATTGTTTATTTGTAAG
CAAAAATCAATTAGCTTTCGTGAGGAATTAATACCATCTGTACAATCTGT
TGTCTGAAAACTGTTGGAAATGCACTAAAGAATTCATTCAAAGTCTCAGA
AAGAATTTCAATTTGTAAAGAGTAGCAAAATCGTAATCAATTTCTTCTAG
ATAAAATCTTTCTAACTTGTTGGATAGACGGAAATTTTGTTTACTAAAAT
GCATATTTTTCTTGAATTTTAGTTAATAATGACGTGGTAAATTTTTATAC
TGTATTAGTAAATATGTTTTAGCGTGCGCATGCAAACTGTGAATTTTGTG
TATTTTTTAAATGAAATGATTGATAAATGTTTATCTAACGATGCTTATAT
ATTGTTACGTCAATGGAATACAAATCATTTAGCATTTACGAATTCTAAAG
AAAATGTCTAATTGTAAATCTCAACTGAAAGATTTTGATTTCATTCGAAT
TTCAACTCCAGATTTAAACGGTTGTCACATGTCAAAGCTTGTCTCGTCGC
AACTTGCTCAACGAATAAAAAACAATGAAGTTGATTTGTATGGTGGTGCT
ATAGCCCTAGGCCCGAGAACCCAATATGTTGGCATTGATGAGTTTACCGA
GAACAAATCCCGAAATGCTTACTTTTTTCCCGATTTAGACACTTTGAAAC
CAATCAAATGGGCCGACGATTTGGAGAGAGATTTCAAAGTCGGTGATGTC
ATAGCAGATATGAAATGGGATGAGACGAGTCCAGTCGAATTTCATCCTCG
AATTGTGGCAGCAAAACAAATCCGGAGACTCGAAGAAATGGATTTGGAAT
TATTTTCCGCTTTTGAACCAGAATTTAGGGCTTTTAAATTAGATTCATAC
GAACCGTTTAGCTCTGGGTTGGACATGTATAAAACAACAATGCTTGCAAA
ATATGAAAAGTTTTTTATGGATGCTGTCACGAAACTTGCGGTGGCCGGCA
TAGACATACAGGATTGTTGCATTGAACACGGTGAAGGTCAGTTAGAAATG
CCTTTATTGCCCTCTTTTGGGATTGCTGCTGCTGATAAAGCTTTTCGATT
CAAGCAAGGAATAAAAGAATTGGCTAAACATCACCAAATGACTATTAGTT
TCATGACCAAACCGTTTTTATCTGAATCAAGCAGTGGCAATCATTTCAAT
CATTCATTATGGTACAAGTCAACGAAGCGGAATGCTATGTTTGACGTAAA
AGGTGAAGATAATTTGTCAGATCTTGCTTTGTATTGGATCGGAGGACTCA
TAAAACATTTGCCAGCCATATCTGCGCTCTGTTGTCCAACAGCAAATTGC
TATCGCCGCCTTCACAATTTCATTGCGCCTGGATCTCTTAATTGGGATAT
AAACGACCGATTTTGCAGTATTCGCGTTAAAAATTTCAATGAGAAAAATA
CTTATATAGAAAATAGGTTACCTTCGAGCGCAGCTTGTCCTTATCATGCT
CTTGCTGCGACTATTGCAGCTGGAATCGATGGCGTAGTTAATAAAATTTA
TCCTCCCCCTAAAGGAGACAAATCTATGGGAGATCTACCATCTAATTTCG
AGGAAGCATTGAATATTCTTGAAAAAGATGATGTTATAAAAGAAGCCCTT
GGTGAAAAATTTGTAAATTATTTCATTAAAATCAAAAGAGATGTGGATTT
AATTGAAATTTTTGGTAAGAAATTAAATGACCAAGAACAATTAGAGTCAG
AAAGAAAGCAGTACTTCGAATATATTTAATTATTCTTTCATTATATTTTG
GCCTGGTTGAACTTTCTTAAAATTTATAAATTAACTTTTTAATTAGTTTT
CTATAATTGATCTATTTTTTAGAAATACAGC
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protein sequence of SMED30010540-orf-1

>SMED30010540-orf-1 ID=SMED30010540-orf-1|Name=SMED30010540-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=442bp
MSNCKSQLKDFDFIRISTPDLNGCHMSKLVSSQLAQRIKNNEVDLYGGAI
ALGPRTQYVGIDEFTENKSRNAYFFPDLDTLKPIKWADDLERDFKVGDVI
ADMKWDETSPVEFHPRIVAAKQIRRLEEMDLELFSAFEPEFRAFKLDSYE
PFSSGLDMYKTTMLAKYEKFFMDAVTKLAVAGIDIQDCCIEHGEGQLEMP
LLPSFGIAAADKAFRFKQGIKELAKHHQMTISFMTKPFLSESSSGNHFNH
SLWYKSTKRNAMFDVKGEDNLSDLALYWIGGLIKHLPAISALCCPTANCY
RRLHNFIAPGSLNWDINDRFCSIRVKNFNEKNTYIENRLPSSAACPYHAL
AATIAAGIDGVVNKIYPPPKGDKSMGDLPSNFEEALNILEKDDVIKEALG
EKFVNYFIKIKRDVDLIEIFGKKLNDQEQLESERKQYFEYI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR008146Gln_synth_cat_dom
IPR014746Gln_synth/guanido_kin_cat_dom
Vocabulary: molecular function
TermDefinition
GO:0004356glutamate-ammonia ligase activity
GO:0003824catalytic activity
Vocabulary: biological process
TermDefinition
GO:0006807nitrogen compound metabolic process
GO:0006542glutamine biosynthetic process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR008146Glutamine synthetase, catalytic domainSMARTSM01230Gln_synt_C_2coord: 112..357
e-value: 3.5E-62
score: 222.6
IPR008146Glutamine synthetase, catalytic domainPFAMPF00120Gln-synt_Ccoord: 114..413
e-value: 4.1E-74
score: 249.6
NoneNo IPR availableGENE3DG3DSA:3.30.590.10coord: 109..434
e-value: 4.3E-84
score: 284.1
NoneNo IPR availablePANTHERPTHR43407FAMILY NOT NAMEDcoord: 9..441
NoneNo IPR availablePANTHERPTHR43407:SF1LENGSINcoord: 9..441
IPR014746Glutamine synthetase/guanido kinase, catalytic domainSUPERFAMILYSSF55931Glutamine synthetase/guanido kinasecoord: 113..416