FR47 domain-containing protein

Overview
NameFR47 domain-containing protein
Smed IDSMED30010515
Length (bp)949
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of FR47 domain-containing protein (SMED30010515) t-SNE clustered cells

Violin plots show distribution of expression levels for FR47 domain-containing protein (SMED30010515) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of FR47 domain-containing protein (SMED30010515) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for FR47 domain-containing protein (SMED30010515) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30010515

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30010515SMESG000066514.1 Contig82GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30010515SMESG000035878.1 Contig82GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30010515SMESG000035878.1 dd_Smed_v4_1705_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
neuronSMED30010515SMESG000035878.1 dd_Smed_v4_1705_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30010515SMESG000035878.1 dd_Smed_v4_1705_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of FR47 domain-containing protein vs. TrEMBL
Match: B4LT96 (N-acetyltransferase domain-containing protein OS=Drosophila virilis OX=7244 GN=Dvir\GJ17751 PE=4 SV=1)

HSP 1 Score: 62.003 bits (149), Expect = 2.711e-7
Identity = 40/179 (22.35%), Postives = 80/179 (44.69%), Query Frame = 1
Query:  376 NQGMIVTFLCLPTNIFEYLLSKSDEHQLKPIFRNCCNTYLNNNRDGDNIP-NLIEGFQLRKIPKENIDEVIKNWKHGRPEQRDWIKNSIENWPSMGVWDVETNEMVGQFIFLFTGTFGALTIKEAYRGKKLAEMLIKGFRECVKECKMEFLIEVEEENVASQNLFIKQNFVEVSHSHYL 909
            + GM+ T   +P    E +L    E QL   F +  + Y    +       +  +GFQL+ + +++   + + W +       +I+  I   PSMG++D +T ++V   I    G    L ++ AY+ +    ++++     + +   +   E+  EN+ S N+F K  F  +   H+L
Sbjct:   94 SSGMLCT--SVPDRYIETVLQVMQEKQLVIEFHHLSDIYHIPAKQALQFHVDCPKGFQLKSLSEQDAHLLDQEWAYSHEGSLFFIQRQIRLCPSMGLYDEDTQQLVAWCIRTQDGLLATLHVQNAYKRRGFGSLIVRALARRIADLGDDVTAEIYAENIPSVNMFNKLGFRVIDQCHWL 270          
BLAST of FR47 domain-containing protein vs. TrEMBL
Match: B4JAP0 (GH11461 OS=Drosophila grimshawi OX=7222 GN=Dgri\GH11461 PE=4 SV=1)

HSP 1 Score: 61.2326 bits (147), Expect = 5.265e-7
Identity = 41/174 (23.56%), Postives = 79/174 (45.40%), Query Frame = 1
Query:  394 TFLCLPTNIFEYLLSKSDEHQLKPI---FRNCCNTYLNNNRDGDNIPNLIEGFQLRKIPKENIDEVIKNWKHGRPEQRDWIKNSIENWPSMGVWDVETNEMVGQFIFLFTGTFGALTIKEAYRGKKLAEMLIKGFRECVKECKMEFLIEVEEENVASQNLFIKQNFVEVSHSHY 906
              LCL +    Y+L    E  +  +    RN  N  +   +     P +  G +LR +  ++   + +NW HG P+   ++K  I+   S+G +D E  +++   + L  G  G L + E ++   L  ++++     + +   E L  V  EN AS+ LF K  F ++ + ++
Sbjct:  112 ALLCLASKSGVYVLHDYGERLVPAVDAYIRNVVNAKMETTQTA--WPPV--GIELRSVDPKDAATINENWPHGSPDSLKFVKRLIDYNVSVGAYD-EQGKLIAWCLRLPIGALGLLQVVETHKRLGLGSLMVRYLSRKISDLGDEVLAPVVTENTASRKLFEKLGFQKIDNVYW 280          
BLAST of FR47 domain-containing protein vs. TrEMBL
Match: A0A0Q9WLN2 (Uncharacterized protein, isoform A OS=Drosophila virilis OX=7244 GN=Dvir\GJ26754 PE=4 SV=1)

HSP 1 Score: 59.6918 bits (143), Expect = 7.696e-7
Identity = 44/184 (23.91%), Postives = 77/184 (41.85%), Query Frame = 1
Query:  394 TFLCLPTNIFEYLLSKSDEHQLKPI---FRNCCNTYLNNNRDG--DNIPNLIE--------GFQLRKIPKENIDEVIKNWKHGRPEQRDWIKNSIENWPSMGVWDVETNEMVGQFIFLFTGTFGALTIKEAYRGKKLAEMLIKGFRECVKECKMEFLIEVEEENVASQNLFIKQNFVEVSHSHY 906
              LCLP+   EYLL    +  +  +    R C N  L   +         L+         G QLR +   +   V  NW +G  +   ++K  IE   S+G +D    +++   + L  G  G L + +++R   L  ++++     + E   E L  V  EN  S+ LF K  F ++ + ++
Sbjct:   17 ALLCLPSGAVEYLLHDYSQRLVPAVDAYIRKCANRQLQTTQTAWYKASKELVATFSTEPPAGIQLRSLNTADAAIVNGNWPYGSKDSVQFVKRLIEYNVSIGAYDA-YGKLLAWCLRLPIGALGLLQVMDSHRRLGLGSLMVRVLSSKISELGDEVLAPVVTENTPSRRLFEKLGFQKIDNVYW 199          
BLAST of FR47 domain-containing protein vs. TrEMBL
Match: A0A0Q9WJL0 (Uncharacterized protein, isoform C OS=Drosophila virilis OX=7244 GN=Dvir\GJ26754 PE=4 SV=1)

HSP 1 Score: 59.3066 bits (142), Expect = 2.377e-6
Identity = 44/184 (23.91%), Postives = 77/184 (41.85%), Query Frame = 1
Query:  394 TFLCLPTNIFEYLLSKSDEHQLKPI---FRNCCNTYLNNNRDG--DNIPNLIE--------GFQLRKIPKENIDEVIKNWKHGRPEQRDWIKNSIENWPSMGVWDVETNEMVGQFIFLFTGTFGALTIKEAYRGKKLAEMLIKGFRECVKECKMEFLIEVEEENVASQNLFIKQNFVEVSHSHY 906
              LCLP+   EYLL    +  +  +    R C N  L   +         L+         G QLR +   +   V  NW +G  +   ++K  IE   S+G +D    +++   + L  G  G L + +++R   L  ++++     + E   E L  V  EN  S+ LF K  F ++ + ++
Sbjct:   98 ALLCLPSGAVEYLLHDYSQRLVPAVDAYIRKCANRQLQTTQTAWYKASKELVATFSTEPPAGIQLRSLNTADAAIVNGNWPYGSKDSVQFVKRLIEYNVSIGAYDA-YGKLLAWCLRLPIGALGLLQVMDSHRRLGLGSLMVRVLSSKISELGDEVLAPVVTENTPSRRLFEKLGFQKIDNVYW 280          
BLAST of FR47 domain-containing protein vs. TrEMBL
Match: A0A0A1X095 (Glycine N-acyltransferase-like protein 3 OS=Zeugodacus cucurbitae OX=28588 GN=GLYATL3 PE=4 SV=1)

HSP 1 Score: 58.5362 bits (140), Expect = 4.180e-6
Identity = 32/119 (26.89%), Postives = 62/119 (52.10%), Query Frame = 1
Query:  526 NLIEGFQLRKIPKENIDEVIKNWKHGRPEQRDWIKNSIENWPSMGVWDVETNEMVGQFIFLFTGTFGALTIKEAYRGKKLAEMLIKGFRECVKECKMEFLIEVEEENVASQNLFIKQNF 882
            ++ EGF LR++  +N ++V   W H  P    +++  I N  S+GV+D   N +V   + L  G+ G L + E+++      ++++   + +    +E    V  +NVAS+++F K  F
Sbjct:  147 DVPEGFTLRRVQPKNAEQVNSVWPHRMPNTVLFVERMIRNADSVGVYDASDN-LVAWCLRLPIGSLGLLQVLESHKRMGFGSLVVRSISKLIASKGLEVTAPVVFQNVASRSMFEKLGF 264          
BLAST of FR47 domain-containing protein vs. Planmine SMEST
Match: SMESG000035878.1 (SMESG000035878.1)

HSP 1 Score: 587.8 bits (1514), Expect = 0.000e+0
Identity = 285/287 (99.30%), Postives = 286/287 (99.65%), Query Frame = 1
Query:   64 QELQCDIKKSPILNVLKSKKAQYLENQNLDRYWHTVRAYQGLKYLVVKKNIFVYDIQNVKVILATFEMKEHHKVYIEFWMNDEWSMKELECAFEEIINIIKVFTNQGMIVTFLCLPTNIFEYLLSKSDEHQLKPIFRNCCNTYLNNNRDGDNIPNLIEGFQLRKIPKENIDEVIKNWKHGRPEQRDWIKNSIENWPSMGVWDVETNEMVGQFIFLFTGTFGALTIKEAYRGKKLAEMLIKGFRECVKECKMEFLIEVEEENVASQNLFIKQNFVEVSHSHYLVYKSN 924
            QELQCDIKKSPILNVLKSKKAQYLENQNLDRYWHTVRAYQGLKYLVVKKNIFVYDIQNVKVILATFEMKEHHKVYIEFWMNDEWSMKELECAFEEI+NIIKVFTNQGMIVTFLCLPTNIFEYLLSKSDEHQLKPIFRNCCNTYLNNNR GDNIPNLIEGFQLRKIPKENIDEVIKNWKHGRPEQRDWIKNSIENWPSMGVWDVETNEMVGQFIFLFTGTFGALTIKEAYRGKKLAEMLIKGFRECVKECKMEFLIEVEEENVASQNLFIKQNFVEVSHSHYLVYKSN
Sbjct:    4 QELQCDIKKSPILNVLKSKKAQYLENQNLDRYWHTVRAYQGLKYLVVKKNIFVYDIQNVKVILATFEMKEHHKVYIEFWMNDEWSMKELECAFEEILNIIKVFTNQGMIVTFLCLPTNIFEYLLSKSDEHQLKPIFRNCCNTYLNNNRGGDNIPNLIEGFQLRKIPKENIDEVIKNWKHGRPEQRDWIKNSIENWPSMGVWDVETNEMVGQFIFLFTGTFGALTIKEAYRGKKLAEMLIKGFRECVKECKMEFLIEVEEENVASQNLFIKQNFVEVSHSHYLVYKSN 290          
BLAST of FR47 domain-containing protein vs. Planmine SMEST
Match: SMESG000044281.1 (SMESG000044281.1)

HSP 1 Score: 184.496 bits (467), Expect = 3.166e-56
Identity = 112/284 (39.44%), Postives = 168/284 (59.15%), Query Frame = 1
Query:   67 ELQCDIKKSPILNVLKSKKAQYLENQNLDRYWHTVRAYQGLKYLVVKKNIFVYDIQNVKVILATFEMKEHHKVY-IEFWMNDEWSMKELECAFEEIINIIKVFTNQGMIVTFLCLPTNIFEYLLSKSDEHQLKPIFRNCCNTYLNNNRDGDNIPNLIEGFQLRKIPKENIDEVIKNWKHGRPEQRDWIKNSIENWPSMGVWDVETNEMVGQFIFLFTGTFGALTIKEAYRGKKLAEMLIKGFRECVKECKMEFLIEVEEENVASQNLFIKQNFVEVSHSHYLVY 915
            EL  D +K+ +L++LK+KK  Y +N + D+Y  T R +Q L  L++KK IFV D+ NV VIL  F  ++   V   E W+ND  S  E+E    +I+   +    +  IV F  LP  + +       +  +   FR     Y  +  +     + I+GFQL  IP +N++ +IKNWK+G  +  DWI+NSIEN+PSMG+WD   N+M+GQFI++ TGT G+LTI   YRG+ LA+ML+ G  + +++  ME  I++EE NV S+ LF    F +V+ S YLV+
Sbjct:    6 ELNSDCEKNLLLDLLKTKKKLYCDNGSFDKYSETGRLFQSLSCLIIKKRIFVNDMNNVNVILLNFTTQKIRTVQNFEVWINDCMSTDEMESINYQILAFSQFLVEKNYIVFFRNLPIYLADNFDKIKTDFNVNIPFRIKTEIYSFDFENKQIQEHQIQGFQLNHIPIKNLETIIKNWKYGVVQDYDWIRNSIENFPSMGIWDASRNKMIGQFIYMITGTHGSLTIDNEYRGRGLAKMLVLGTLKEIRQRNMEIFIDIEEGNVVSKCLFENLGFEKVTESIYLVF 289          
BLAST of FR47 domain-containing protein vs. Planmine SMEST
Match: SMESG000063826.1 (SMESG000063826.1)

HSP 1 Score: 78.5666 bits (192), Expect = 2.105e-16
Identity = 67/276 (24.28%), Postives = 128/276 (46.38%), Query Frame = 1
Query:   97 ILNVLKSKKAQYLENQNLDRYWHTVRAYQGLKYLVVKKNIFVYDIQNVKVILATFEMKEHHK---VYIEFWMNDEWSMKELECAFEEIINIIKVFTNQGMIVTFLCLPTNIFEYLLSKSDEHQLKPIFRNCCNTYLNNNRDGDNIPNLIEGFQLRKIPKENIDEVIKNWKHG-RPEQRDWIKNSIENWPSMGVWDVETNEMVGQFIFLFTGTFGALTIKEAYRGKKLAEMLIKGFRECVKECKMEFLIEVEEENVASQNLFIKQNFVEVSHSHYLV 912
            IL  LKS   ++ ++ N + +WH+ R    LK  +V + ++V        IL+ +  K   K   VY+  + +        + A E +I    +   Q     +   P+ +    + K + +  + I  NC      N          IEGF  + + + + + V + +K+   P+   WI+ SI++ PSMG ++   +++VGQFI + +G FG L + +  +G KL + +++   + + +     ++E E  N  S NLF    F   +HS+Y++
Sbjct:   13 ILKRLKSLVDKFQQSNNNEMWWHSTRMEYSLKNELVPQQVYVDRFPECNFILSKYTNKACGKNIEVYVANFEDKSIISDACDAALE-MIACENMSYGQIQSSPYFLYPSLMKS--VKKYELYLFEDIGANCMTFPYKNIDKLIEKTKPIEGFYCKPLRECDAELVNQRFKYANHPDTYKWIRKSIQDLPSMGCYN-SNDQLVGQFITMESGNFGGLFVIDECKGLKLGKWIVQETTKLLHKLNKPMILETEFSNKVSYNLFTNLGFETRAHSYYML 284          
The following BLAST results are available for this feature:
BLAST of FR47 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FR47 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FR47 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FR47 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FR47 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FR47 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FR47 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FR47 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
B4LT962.711e-722.35N-acetyltransferase domain-containing protein OS=D... [more]
B4JAP05.265e-723.56GH11461 OS=Drosophila grimshawi OX=7222 GN=Dgri\GH... [more]
A0A0Q9WLN27.696e-723.91Uncharacterized protein, isoform A OS=Drosophila v... [more]
A0A0Q9WJL02.377e-623.91Uncharacterized protein, isoform C OS=Drosophila v... [more]
A0A0A1X0954.180e-626.89Glycine N-acyltransferase-like protein 3 OS=Zeugod... [more]
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BLAST of FR47 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FR47 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FR47 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FR47 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FR47 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FR47 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000035878.10.000e+099.30SMESG000035878.1[more]
SMESG000044281.13.166e-5639.44SMESG000044281.1[more]
SMESG000063826.12.105e-1624.28SMESG000063826.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010515 ID=SMED30010515|Name=FR47 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=949bp
GACCTTTAGATTTTGCAATAATTTATTCATTTCAATTTCACAATTTGAAT
CACAATGACGTTCCAAGAGCTTCAGTGTGATATTAAAAAGAGTCCGATTC
TCAATGTATTAAAATCAAAAAAGGCTCAGTATTTGGAGAATCAAAACCTG
GACAGGTACTGGCATACGGTACGAGCTTATCAAGGCCTCAAATATCTAGT
TGTCAAAAAGAACATTTTCGTGTACGATATTCAGAACGTAAAAGTCATTT
TGGCAACATTCGAAATGAAAGAACACCATAAGGTATACATTGAATTCTGG
ATGAATGACGAGTGGTCAATGAAAGAATTGGAATGCGCATTTGAAGAGAT
AATAAATATAATAAAGGTATTTACAAATCAAGGCATGATTGTCACATTTC
TATGCCTACCAACTAATATTTTCGAATATCTACTGTCAAAGTCTGATGAG
CATCAATTGAAACCGATTTTTCGGAATTGTTGCAACACCTACCTTAACAA
CAATCGGGATGGTGATAATATTCCAAATTTGATTGAAGGTTTTCAACTGA
GAAAGATTCCCAAAGAAAATATCGACGAAGTTATCAAGAATTGGAAACAT
GGAAGACCGGAACAAAGGGATTGGATCAAAAACTCCATTGAGAATTGGCC
TTCAATGGGAGTTTGGGATGTTGAAACTAATGAAATGGTTGGACAGTTTA
TTTTTCTATTTACTGGTACTTTTGGGGCTTTGACGATTAAAGAAGCATAC
AGAGGAAAGAAATTAGCAGAGATGTTGATAAAAGGTTTTAGGGAATGTGT
GAAGGAGTGTAAAATGGAGTTCCTTATTGAAGTAGAAGAGGAGAATGTTG
CATCGCAAAACCTTTTCATTAAACAAAATTTTGTTGAAGTTTCACATTCT
CATTATTTAGTTTATAAATCCAATTGATGGATGAATAAATTAACAAAAT
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protein sequence of SMED30010515-orf-1

>SMED30010515-orf-1 ID=SMED30010515-orf-1|Name=SMED30010515-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=291bp
MTFQELQCDIKKSPILNVLKSKKAQYLENQNLDRYWHTVRAYQGLKYLVV
KKNIFVYDIQNVKVILATFEMKEHHKVYIEFWMNDEWSMKELECAFEEII
NIIKVFTNQGMIVTFLCLPTNIFEYLLSKSDEHQLKPIFRNCCNTYLNNN
RDGDNIPNLIEGFQLRKIPKENIDEVIKNWKHGRPEQRDWIKNSIENWPS
MGVWDVETNEMVGQFIFLFTGTFGALTIKEAYRGKKLAEMLIKGFRECVK
ECKMEFLIEVEEENVASQNLFIKQNFVEVSHSHYLVYKSN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0016740transferase activity
GO:0016746transferase activity, transferring acyl groups
GO:0016747transferase activity, transferring acyl groups other than amino-acyl groups
GO:0008080N-acetyltransferase activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0000099neuron
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR013653FR47
IPR016181Acyl_CoA_acyltransferase
IPR000182GNAT_dom
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:3.40.630.30coord: 154..276
e-value: 2.0E-20
score: 75.2
NoneNo IPR availablePANTHERPTHR20958UNCHARACTERIZEDcoord: 76..286
IPR013653FR47-likePFAMPF08445FR47coord: 201..282
e-value: 5.1E-5
score: 23.2
IPR000182GNAT domainPROSITEPS51186GNATcoord: 163..290
score: 9.545
IPR016181Acyl-CoA N-acyltransferaseSUPERFAMILYSSF55729Acyl-CoA N-acyltransferases (Nat)coord: 143..283