Apoptotic chromatin condensation inducer in the nucleus

Overview
NameApoptotic chromatin condensation inducer in the nucleus
Smed IDSMED30010510
Length (bp)2143
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Apoptotic chromatin condensation inducer in the nucleus (SMED30010510) t-SNE clustered cells

Violin plots show distribution of expression levels for Apoptotic chromatin condensation inducer in the nucleus (SMED30010510) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Apoptotic chromatin condensation inducer in the nucleus (SMED30010510) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Apoptotic chromatin condensation inducer in the nucleus (SMED30010510) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30010510

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30010510h1SMcG0018942 SmedASXL_011907SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30010510h1SMcG0018942 SmedASXL_011907SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X1 cellSMED30010510h1SMcG0018942 SmedASXL_009872SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30010510h1SMcG0018942 SmedASXL_009872SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
neoblastSMED30010510h1SMcG0018942 dd_Smed_v4_3458_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30010510h1SMcG0018942 dd_Smed_v4_4153_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30010510h1SMcG0018942 dd_Smed_v4_4153_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30010510h1SMcG0018942 dd_Smed_v4_4153_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Human
Match: ACIN1 (apoptotic chromatin condensation inducer 1 [Source:HGNC Symbol;Acc:HGNC:17066])

HSP 1 Score: 80.4925 bits (197), Expect = 8.618e-15
Identity = 37/109 (33.94%), Postives = 61/109 (55.96%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPA-QKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            G    ++ P R A     P+   S+++ I NLVRPFTL QL+++L   G + +   W++KIKS  +V Y+T   A + +  + G +WP  NPK L  D+    E+++ +
Sbjct:  930 GVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHR 1038
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Human
Match: ACIN1 (apoptotic chromatin condensation inducer 1 [Source:HGNC Symbol;Acc:HGNC:17066])

HSP 1 Score: 80.1073 bits (196), Expect = 9.177e-15
Identity = 37/109 (33.94%), Postives = 61/109 (55.96%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPA-QKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            G    ++ P R A     P+   S+++ I NLVRPFTL QL+++L   G + +   W++KIKS  +V Y+T   A + +  + G +WP  NPK L  D+    E+++ +
Sbjct:  975 GVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHR 1083
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Human
Match: ACIN1 (apoptotic chromatin condensation inducer 1 [Source:HGNC Symbol;Acc:HGNC:17066])

HSP 1 Score: 80.1073 bits (196), Expect = 9.526e-15
Identity = 37/109 (33.94%), Postives = 61/109 (55.96%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPA-QKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            G    ++ P R A     P+   S+++ I NLVRPFTL QL+++L   G + +   W++KIKS  +V Y+T   A + +  + G +WP  NPK L  D+    E+++ +
Sbjct:  988 GVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHR 1096
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Human
Match: ACIN1 (apoptotic chromatin condensation inducer 1 [Source:HGNC Symbol;Acc:HGNC:17066])

HSP 1 Score: 80.1073 bits (196), Expect = 9.761e-15
Identity = 37/109 (33.94%), Postives = 61/109 (55.96%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPA-QKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            G    ++ P R A     P+   S+++ I NLVRPFTL QL+++L   G + +   W++KIKS  +V Y+T   A + +  + G +WP  NPK L  D+    E+++ +
Sbjct:  948 GVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHR 1056
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Human
Match: ACIN1 (apoptotic chromatin condensation inducer 1 [Source:HGNC Symbol;Acc:HGNC:17066])

HSP 1 Score: 78.5666 bits (192), Expect = 1.646e-14
Identity = 37/109 (33.94%), Postives = 61/109 (55.96%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPA-QKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            G    ++ P R A     P+   S+++ I NLVRPFTL QL+++L   G + +   W++KIKS  +V Y+T   A + +  + G +WP  NPK L  D+    E+++ +
Sbjct:  229 GVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHR 337
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Celegans
Match: acin-1 (ACINus (Mammalian Apoptotic Chromatin condensation Inducer in the Nucleus) homolog [Source:UniProtKB/TrEMBL;Acc:P91156])

HSP 1 Score: 55.0694 bits (131), Expect = 1.280e-7
Identity = 26/75 (34.67%), Postives = 43/75 (57.33%), Query Frame = 2 
Query: 1124 SDVLRIDNLVRPFTLIQLQDMLALQ-GLVTDLWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDF 1345
            S+V+ I  L RPFT  QL+  +    G + DLW++K+KS  +V+  +++ A +    ++   WP  NPK LS  +
Sbjct:  293 SNVVHIRGLTRPFTEGQLRAEIQKNCGEIVDLWMDKVKSHCFVKLNSDADAGNVISAMNNVVWPDGNPKRLSIVY 367
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Fly
Match: Acn (gene:FBgn0263198 transcript:FBtr0336842)

HSP 1 Score: 89.3521 bits (220), Expect = 4.974e-18
Identity = 46/106 (43.40%), Postives = 64/106 (60.38%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPAQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD---LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREME 1366
             A +IV  P   +PA   +N AS VL I NLVRPFT++QL+ +LA  G + +    W+++IKS  YV Y+TE  A   +  + G RWP  NPK L+ DF S  +M+
Sbjct:  428 AAPHIVRDP---SPA---RNRASHVLYITNLVRPFTVLQLKGLLARTGKIVEEDGFWIDRIKSKCYVAYSTEDEAIETRHALHGVRWPVSNPKCLNVDFGSRTDMD 527
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Fly
Match: Acn (gene:FBgn0263198 transcript:FBtr0081145)

HSP 1 Score: 89.3521 bits (220), Expect = 4.974e-18
Identity = 46/106 (43.40%), Postives = 64/106 (60.38%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPAQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD---LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREME 1366
             A +IV  P   +PA   +N AS VL I NLVRPFT++QL+ +LA  G + +    W+++IKS  YV Y+TE  A   +  + G RWP  NPK L+ DF S  +M+
Sbjct:  428 AAPHIVRDP---SPA---RNRASHVLYITNLVRPFTVLQLKGLLARTGKIVEEDGFWIDRIKSKCYVAYSTEDEAIETRHALHGVRWPVSNPKCLNVDFGSRTDMD 527
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Fly
Match: Acn (gene:FBgn0263198 transcript:FBtr0081144)

HSP 1 Score: 89.3521 bits (220), Expect = 4.974e-18
Identity = 46/106 (43.40%), Postives = 64/106 (60.38%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPAQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD---LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREME 1366
             A +IV  P   +PA   +N AS VL I NLVRPFT++QL+ +LA  G + +    W+++IKS  YV Y+TE  A   +  + G RWP  NPK L+ DF S  +M+
Sbjct:  428 AAPHIVRDP---SPA---RNRASHVLYITNLVRPFTVLQLKGLLARTGKIVEEDGFWIDRIKSKCYVAYSTEDEAIETRHALHGVRWPVSNPKCLNVDFGSRTDMD 527
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Zebrafish
Match: BX465202.1 (apoptotic chromatin condensation inducer 1a [Source:NCBI gene;Acc:368893])

HSP 1 Score: 88.9669 bits (219), Expect = 9.061e-18
Identity = 43/119 (36.13%), Postives = 67/119 (56.30%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAP-AQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMKEKGDTGTNPP 1405
            G    ++ P R A     P+   S+++ + NLVRPFTL QL+++L   G V +   W++KIKS  YV Y++   A + +  + G +WP  NPK LS DF +  E+++ +  G  G  PP
Sbjct:  514 GVSITIDDPVRTAKQPSPPRGKLSNIVHVCNLVRPFTLGQLKELLNRTGTVVEESFWIDKIKSHCYVTYSSAEEAMATRTALHGVKWPQSNPKFLSVDFCTQDELDFHRGLGPAGEKPP 632
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Zebrafish
Match: acin1a (apoptotic chromatin condensation inducer 1a [Source:ZFIN;Acc:ZDB-GENE-030616-583])

HSP 1 Score: 88.9669 bits (219), Expect = 9.132e-18
Identity = 43/119 (36.13%), Postives = 67/119 (56.30%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAP-AQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMKEKGDTGTNPP 1405
            G    ++ P R A     P+   S+++ + NLVRPFTL QL+++L   G V +   W++KIKS  YV Y++   A + +  + G +WP  NPK LS DF +  E+++ +  G  G  PP
Sbjct:  513 GVSITIDDPVRTAKQPSPPRGKLSNIVHVCNLVRPFTLGQLKELLNRTGTVVEESFWIDKIKSHCYVTYSSAEEAMATRTALHGVKWPQSNPKFLSVDFCTQDELDFHRGLGPAGEKPP 631
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Zebrafish
Match: acin1a (apoptotic chromatin condensation inducer 1a [Source:ZFIN;Acc:ZDB-GENE-030616-583])

HSP 1 Score: 87.4261 bits (215), Expect = 1.473e-17
Identity = 43/119 (36.13%), Postives = 67/119 (56.30%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAP-AQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMKEKGDTGTNPP 1405
            G    ++ P R A     P+   S+++ + NLVRPFTL QL+++L   G V +   W++KIKS  YV Y++   A + +  + G +WP  NPK LS DF +  E+++ +  G  G  PP
Sbjct:  204 GVSITIDDPVRTAKQPSPPRGKLSNIVHVCNLVRPFTLGQLKELLNRTGTVVEESFWIDKIKSHCYVTYSSAEEAMATRTALHGVKWPQSNPKFLSVDFCTQDELDFHRGLGPAGEKPP 322
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Zebrafish
Match: acin1a (apoptotic chromatin condensation inducer 1a [Source:ZFIN;Acc:ZDB-GENE-030616-583])

HSP 1 Score: 87.0409 bits (214), Expect = 2.213e-17
Identity = 43/119 (36.13%), Postives = 67/119 (56.30%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAP-AQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMKEKGDTGTNPP 1405
            G    ++ P R A     P+   S+++ + NLVRPFTL QL+++L   G V +   W++KIKS  YV Y++   A + +  + G +WP  NPK LS DF +  E+++ +  G  G  PP
Sbjct:  228 GVSITIDDPVRTAKQPSPPRGKLSNIVHVCNLVRPFTLGQLKELLNRTGTVVEESFWIDKIKSHCYVTYSSAEEAMATRTALHGVKWPQSNPKFLSVDFCTQDELDFHRGLGPAGEKPP 346
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Zebrafish
Match: acin1b (apoptotic chromatin condensation inducer 1b [Source:ZFIN;Acc:ZDB-GENE-030826-12])

HSP 1 Score: 79.7221 bits (195), Expect = 8.873e-15
Identity = 38/105 (36.19%), Postives = 62/105 (59.05%), Query Frame = 2 
Query: 1109 PKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK-----EKGDTGTNP 1402
            P+   S+++ + +LVRPFTL QL+ +L   G + +   W++KIKS  YV Y+T   A + +E + G +WP+ NPK+L  DF    E+++ K     E+   G +P
Sbjct:  907 PRGKTSNIIHVLHLVRPFTLGQLKLLLNRTGTMVEEGFWIDKIKSHCYVTYSTVEEAVATREALHGVKWPASNPKVLRVDFSDQDELDFHKGLISGERAGVGHDP 1011
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Xenopus
Match: ACIN1 (apoptotic chromatin condensation inducer 1 [Source:NCBI gene;Acc:407918])

HSP 1 Score: 85.8853 bits (211), Expect = 1.520e-16
Identity = 41/110 (37.27%), Postives = 64/110 (58.18%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAP--AQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            G    ++ P R A      P+N  S ++ I NLVRPFTL QL+++L+  G + +   W++KIKS  YV Y+T   A + + ++ G +WP  NPK LS DF    E+++ +
Sbjct: 1552 GVSVTIDDPVRTASQLPSPPRNKISCIVHICNLVRPFTLGQLKELLSRTGAIIEENFWIDKIKSHCYVTYSTTEEAVATRNSLHGVKWPQSNPKFLSVDFAEQDELDFHR 1661
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Xenopus
Match: ACIN1 (apoptotic chromatin condensation inducer 1 [Source:NCBI gene;Acc:407918])

HSP 1 Score: 85.8853 bits (211), Expect = 1.542e-16
Identity = 41/110 (37.27%), Postives = 64/110 (58.18%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAP--AQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            G    ++ P R A      P+N  S ++ I NLVRPFTL QL+++L+  G + +   W++KIKS  YV Y+T   A + + ++ G +WP  NPK LS DF    E+++ +
Sbjct: 1603 GVSVTIDDPVRTASQLPSPPRNKISCIVHICNLVRPFTLGQLKELLSRTGAIIEENFWIDKIKSHCYVTYSTTEEAVATRNSLHGVKWPQSNPKFLSVDFAEQDELDFHR 1712
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Xenopus
Match: ACIN1 (apoptotic chromatin condensation inducer 1 [Source:NCBI gene;Acc:407918])

HSP 1 Score: 85.8853 bits (211), Expect = 1.546e-16
Identity = 41/110 (37.27%), Postives = 64/110 (58.18%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAP--AQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            G    ++ P R A      P+N  S ++ I NLVRPFTL QL+++L+  G + +   W++KIKS  YV Y+T   A + + ++ G +WP  NPK LS DF    E+++ +
Sbjct: 1625 GVSVTIDDPVRTASQLPSPPRNKISCIVHICNLVRPFTLGQLKELLSRTGAIIEENFWIDKIKSHCYVTYSTTEEAVATRNSLHGVKWPQSNPKFLSVDFAEQDELDFHR 1734
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Xenopus
Match: ACIN1 (apoptotic chromatin condensation inducer 1 [Source:NCBI gene;Acc:407918])

HSP 1 Score: 83.9593 bits (206), Expect = 3.196e-16
Identity = 41/110 (37.27%), Postives = 64/110 (58.18%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAP--AQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            G    ++ P R A      P+N  S ++ I NLVRPFTL QL+++L+  G + +   W++KIKS  YV Y+T   A + + ++ G +WP  NPK LS DF    E+++ +
Sbjct:  242 GVSVTIDDPVRTASQLPSPPRNKISCIVHICNLVRPFTLGQLKELLSRTGAIIEENFWIDKIKSHCYVTYSTTEEAVATRNSLHGVKWPQSNPKFLSVDFAEQDELDFHR 351
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Xenopus
Match: ACIN1 (apoptotic chromatin condensation inducer 1 [Source:NCBI gene;Acc:407918])

HSP 1 Score: 83.9593 bits (206), Expect = 3.298e-16
Identity = 41/110 (37.27%), Postives = 64/110 (58.18%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAP--AQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            G    ++ P R A      P+N  S ++ I NLVRPFTL QL+++L+  G + +   W++KIKS  YV Y+T   A + + ++ G +WP  NPK LS DF    E+++ +
Sbjct:  244 GVSVTIDDPVRTASQLPSPPRNKISCIVHICNLVRPFTLGQLKELLSRTGAIIEENFWIDKIKSHCYVTYSTTEEAVATRNSLHGVKWPQSNPKFLSVDFAEQDELDFHR 353
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Mouse
Match: Acin1 (apoptotic chromatin condensation inducer 1 [Source:MGI Symbol;Acc:MGI:1891824])

HSP 1 Score: 80.1073 bits (196), Expect = 6.537e-15
Identity = 37/109 (33.94%), Postives = 61/109 (55.96%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPA-QKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            G    ++ P R A     P+   S+++ I NLVRPFTL QL+++L   G + +   W++KIKS  +V Y+T   A + +  + G +WP  NPK L  D+    E+++ +
Sbjct:  921 GVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHR 1029
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Mouse
Match: Acin1 (apoptotic chromatin condensation inducer 1 [Source:MGI Symbol;Acc:MGI:1891824])

HSP 1 Score: 79.7221 bits (195), Expect = 7.946e-15
Identity = 37/109 (33.94%), Postives = 61/109 (55.96%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPA-QKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            G    ++ P R A     P+   S+++ I NLVRPFTL QL+++L   G + +   W++KIKS  +V Y+T   A + +  + G +WP  NPK L  D+    E+++ +
Sbjct:  947 GVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHR 1055
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Mouse
Match: Acin1 (apoptotic chromatin condensation inducer 1 [Source:MGI Symbol;Acc:MGI:1891824])

HSP 1 Score: 79.7221 bits (195), Expect = 8.448e-15
Identity = 37/109 (33.94%), Postives = 61/109 (55.96%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPA-QKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            G    ++ P R A     P+   S+++ I NLVRPFTL QL+++L   G + +   W++KIKS  +V Y+T   A + +  + G +WP  NPK L  D+    E+++ +
Sbjct:  987 GVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHR 1095
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Mouse
Match: Acin1 (apoptotic chromatin condensation inducer 1 [Source:MGI Symbol;Acc:MGI:1891824])

HSP 1 Score: 78.1814 bits (191), Expect = 1.396e-14
Identity = 37/109 (33.94%), Postives = 61/109 (55.96%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPA-QKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            G    ++ P R A     P+   S+++ I NLVRPFTL QL+++L   G + +   W++KIKS  +V Y+T   A + +  + G +WP  NPK L  D+    E+++ +
Sbjct:  201 GVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHR 309
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Mouse
Match: Acin1 (apoptotic chromatin condensation inducer 1 [Source:MGI Symbol;Acc:MGI:1891824])

HSP 1 Score: 78.1814 bits (191), Expect = 1.636e-14
Identity = 37/109 (33.94%), Postives = 61/109 (55.96%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPA-QKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            G    ++ P R A     P+   S+++ I NLVRPFTL QL+++L   G + +   W++KIKS  +V Y+T   A + +  + G +WP  NPK L  D+    E+++ +
Sbjct:  229 GVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHR 337
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. UniProt/SwissProt
Match: sp|Q9UKV3|ACINU_HUMAN (Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2)

HSP 1 Score: 80.1073 bits (196), Expect = 4.575e-14
Identity = 37/109 (33.94%), Postives = 61/109 (55.96%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPA-QKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            G    ++ P R A     P+   S+++ I NLVRPFTL QL+++L   G + +   W++KIKS  +V Y+T   A + +  + G +WP  NPK L  D+    E+++ +
Sbjct:  988 GVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHR 1096
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. UniProt/SwissProt
Match: sp|Q9JIX8|ACINU_MOUSE (Apoptotic chromatin condensation inducer in the nucleus OS=Mus musculus OX=10090 GN=Acin1 PE=1 SV=3)

HSP 1 Score: 79.7221 bits (195), Expect = 5.909e-14
Identity = 37/109 (33.94%), Postives = 61/109 (55.96%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPA-QKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            G    ++ P R A     P+   S+++ I NLVRPFTL QL+++L   G + +   W++KIKS  +V Y+T   A + +  + G +WP  NPK L  D+    E+++ +
Sbjct:  987 GVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHR 1095
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. TrEMBL
Match: A0A0X3QB76 (Apoptotic chromatin condensation inducer in the nucleus OS=Schistocephalus solidus OX=70667 GN=ACINU PE=4 SV=1)

HSP 1 Score: 138.272 bits (347), Expect = 3.081e-31
Identity = 64/121 (52.89%), Postives = 84/121 (69.42%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPAQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQ-GLVTDLWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMKEKGDTG-TNPPSHI 1414
            G GY+ EGPERI PA + ++  ++++ I  L+RPFT  QL  M+  Q G V +LWL+KIKS A VR  T+  A S +E IDGCRWPSINP++L CDF S   +EW+KE GD+G  NPP H+
Sbjct:   77 GVGYLAEGPERIEPAAENRHPPTELVYIRFLMRPFTPGQLSKMIESQFGKVRELWLDKIKSSAVVRMETQEAAKSCREGIDGCRWPSINPRILRCDFASEALLEWLKEHGDSGDRNPPRHL 197
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. TrEMBL
Match: A0A0X3PJR0 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR167424 PE=4 SV=1)

HSP 1 Score: 138.272 bits (347), Expect = 2.112e-30
Identity = 64/121 (52.89%), Postives = 84/121 (69.42%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPAQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQ-GLVTDLWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMKEKGDTG-TNPPSHI 1414
            G GY+ EGPERI PA + ++  ++++ I  L+RPFT  QL  M+  Q G V +LWL+KIKS A VR  T+  A S +E IDGCRWPSINP++L CDF S   +EW+KE GD+G  NPP H+
Sbjct:  242 GVGYLAEGPERIEPAAENRHPPTELVYIRFLMRPFTPGQLSKMIESQFGKVRELWLDKIKSSAVVRMETQEAAKSCREGIDGCRWPSINPRILRCDFASEALLEWLKEHGDSGDRNPPRHL 362
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. TrEMBL
Match: A0A5K3FM63 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 127.487 bits (319), Expect = 5.558e-27
Identity = 60/117 (51.28%), Postives = 77/117 (65.81%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPAQKPKNIASDVLRIDNLVRPFTLIQLQDML-ALQGLVTDLWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMKEKGDTGTNPP 1405
            G G+IVEGPER++ A   K   S ++ I  LVRPFT  QL  ML A  G   +LWL+KIKS A VR   E+VA+  +E +DGCRWPSINPK+L C+F S     W+K+ G++G  PP
Sbjct:  250 GVGFIVEGPERVSAAAAAKCPPSQMVYIRCLVRPFTAGQLSAMLEAHFGKPEELWLDKIKSSAIVRLADETVAARCREGLDGCRWPSINPKILHCEFASQELFTWLKQHGESGDRPP 366
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. TrEMBL
Match: A0A5K3FJH1 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 127.872 bits (320), Expect = 6.587e-27
Identity = 60/117 (51.28%), Postives = 77/117 (65.81%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPAQKPKNIASDVLRIDNLVRPFTLIQLQDML-ALQGLVTDLWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMKEKGDTGTNPP 1405
            G G+IVEGPER++ A   K   S ++ I  LVRPFT  QL  ML A  G   +LWL+KIKS A VR   E+VA+  +E +DGCRWPSINPK+L C+F S     W+K+ G++G  PP
Sbjct:  331 GVGFIVEGPERVSAAAAAKCPPSQMVYIRCLVRPFTAGQLSAMLEAHFGKPEELWLDKIKSSAIVRLADETVAARCREGLDGCRWPSINPKILHCEFASQELFTWLKQHGESGDRPP 447
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. TrEMBL
Match: A0A158R9A6 (Uncharacterized protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS6932 PE=4 SV=1)

HSP 1 Score: 125.176 bits (313), Expect = 1.419e-25
Identity = 63/171 (36.84%), Postives = 94/171 (54.97%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPAQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQ-GLVTDLWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMKEKGDTGTNPPSHIRQPTTQQDQKEPPAKPKDNKESIPSQQEQAATTDNEWRHQDKPKQTAGTDN 1567
              G+ VE PER+ PA + K  +S ++ I  LVRPFT  QL  ML    G  ++LWL++IKS A  R++ E VA+  +E +DGCRWPSINP++L C+F S   + W+KE G+ G  PP   R      D     +  ++N  S+  ++ +    D E     K ++  G + 
Sbjct: 1349 AVGFTVEAPERVNPAAEAKCSSSSLVYIRCLVRPFTAAQLATMLETHFGRASELWLDRIKSTAVARFSNEEVAAKCREGLDGCRWPSINPRILQCEFASEALLAWLKEHGEAGDKPPP--RHLLGGGDAVNAASANENNGSSVERKRPEKLMDDAEATSGAKRRRIVGGEG 1517
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Cavefish
Match: ENSAMXT00000021624.2 (pep primary_assembly:Astyanax_mexicanus-2.0:16:6910416:6930828:-1 gene:ENSAMXG00000020999.2 transcript:ENSAMXT00000021624.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 85.5001 bits (210), Expect = 1.128e-16
Identity = 35/91 (38.46%), Postives = 57/91 (62.64%), Query Frame = 2 
Query: 1109 PKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVT--DLWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            P+   S+++ + NLVRPFTL QL+++L+  G +   D W++KIKS  YV Y++   A + +  + G +WP  NPK LS DF    E+++ +
Sbjct:  880 PRGKISNIVHVCNLVRPFTLGQLKELLSRTGTIVEEDFWIDKIKSHCYVSYSSLEEAQATRAALHGVKWPQSNPKFLSVDFCQKEELDFHR 970
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Cavefish
Match: acin1b (apoptotic chromatin condensation inducer in the nucleus-like [Source:NCBI gene;Acc:103024124])

HSP 1 Score: 85.5001 bits (210), Expect = 1.189e-16
Identity = 38/91 (41.76%), Postives = 59/91 (64.84%), Query Frame = 2 
Query: 1109 PKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMK 1375
            P+   S+V+ + NLVRPFTL QL+++L   G V +   W++KIKS  YV Y+++  A + +E + G +WPS NPK+L  DF    E+++ K
Sbjct:  999 PRGKISNVIHVCNLVRPFTLGQLKELLNRTGTVLEEGFWIDKIKSHCYVTYSSKEEAVATREALHGVKWPSSNPKVLRVDFCEQDELDFHK 1089
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Medaka
Match: acin1b (apoptotic chromatin condensation inducer in the nucleus [Source:NCBI gene;Acc:101170959])

HSP 1 Score: 85.8853 bits (211), Expect = 9.103e-17
Identity = 43/128 (33.59%), Postives = 69/128 (53.91%), Query Frame = 2 
Query: 1058 GAGYIVEGPERIAPA-QKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTD--LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMKEKGDTGTNPPSHIRQPTTQ 1432
            G    ++ P R A     P+   S+++ + NLVRPFTL+QL+++L   G + +   W++KIKS  YV Y+    A + +E + G +WP  NPK+L  DF    E+++ K     G   P  + +P  Q
Sbjct:  792 GVSVTIDDPVRTAKQPSPPRGKVSNIVHVTNLVRPFTLLQLKELLNRTGTMVEEGFWIDKIKSHCYVTYSATEEAVATREALHGVKWPPSNPKVLRVDFCEQDELDFHK-----GVVKPEKVEEPVIQ 914
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Medaka
Match: ENSORLT00000044127.1 (apoptotic chromatin condensation inducer 1 [Source:NCBI gene;Acc:111949076])

HSP 1 Score: 84.7297 bits (208), Expect = 2.102e-16
Identity = 40/94 (42.55%), Postives = 60/94 (63.83%), Query Frame = 2 
Query: 1109 PKNIASDVLRIDNLVRPFTLIQLQDMLALQG-LVTD-LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMKEKG 1384
            P+   S+++ I NLVRPFTL QL+++L+  G LV D  W++KIKS  YV Y++   A + +  + G +WP  NPK+LS DF    E+++ K  G
Sbjct: 1329 PRGKVSNIVHICNLVRPFTLGQLKELLSRTGTLVEDGFWIDKIKSHCYVTYSSVEEAVATRTALHGVKWPQSNPKVLSVDFCQQDELDFHKSLG 1422
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Medaka
Match: ENSORLT00000015255.2 (apoptotic chromatin condensation inducer 1 [Source:NCBI gene;Acc:111949076])

HSP 1 Score: 82.8037 bits (203), Expect = 4.394e-16
Identity = 40/94 (42.55%), Postives = 60/94 (63.83%), Query Frame = 2 
Query: 1109 PKNIASDVLRIDNLVRPFTLIQLQDMLALQG-LVTD-LWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMKEKG 1384
            P+   S+++ I NLVRPFTL QL+++L+  G LV D  W++KIKS  YV Y++   A + +  + G +WP  NPK+LS DF    E+++ K  G
Sbjct:  234 PRGKVSNIVHICNLVRPFTLGQLKELLSRTGTLVEDGFWIDKIKSHCYVTYSSVEEAVATRTALHGVKWPQSNPKVLSVDFCQQDELDFHKSLG 327
[Close]
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Planmine SMEST
Match: SMESG000027295.1 (SMESG000027295.1)

HSP 1 Score: 1105.12 bits (2857), Expect = 0.000e+0
Identity = 644/668 (96.41%), Postives = 646/668 (96.71%), Query Frame = 2 
Query:   41 MSQTETFFLPDGRKTSDLKVNXXXXXXXXXXXXXXXNKPELLNRLNESFTRSVAEASEIEKENSVSSETQNELNNTNQDENEDISQNDHRTVKCKISRYNVDLDAVDDQIPLNAEVNQSVDALDLYVPIDDSLNITDESIQEERIQVTISRNEETETNDNGDDTRLVETLTTDKRTVICVSNDSENDKPTEIDTEAVTDATNEKEPLTVEIEDKSQLVTAEPEPTENEPDEMENIELETQIEMYDVDNIDMDGQMEMYEEHKEELTNTQDQKDENIIVNIEKDLRETEFLXXXXXXXXXXXXXISVPITARLGXXXXXXXXXXXXXXXXXXXXXXXXXXGAGYIVEGPERIAPAQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTDLWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMKEKGDTGTNPPSHIRQPTTQQDQKEPPAKPKDNKESIPSQQEQAATT----------------DNEWRHQDKPKQTAGTDNEWRYQDKPKQTSGADNEWRHQDKMKPSTREQPQNKFDRNDDAKRQRMKDHREALPDNNRRRQRSPQPDHRRHYDNQKEQXXXXXXXXXXXXXXQ---PPPPAAKLLEDIFRKTVTQPAIYWLPVANXXXXXXXXXXXXAVKVQ 1987
            MSQTETFFLPDGRKTSDLKVNELKKELEKLGKSKSGNKPELLNRLNESFTRSVAEASEIEKENSVSSETQNELNNTNQDENEDISQNDHRTVKCKISRYNVDLDAVDDQIPLNAEVNQSVDALDLYVPIDDSLNITDESIQEERIQVTISRNEETETNDNGDDTRLVETLTTDKRTVICVSNDSENDKPTEIDTEAVTDATNE EPLTVEIEDKSQLVTAEPEPTENEPDEMENIELETQIEMYDVDNIDMDGQMEMYEEHKEE+TNTQDQKDENIIVNIEKDLRETEFLEVGTNEETEEGEVISVPITARLGKRKVKEESKSHSSPKKSKKKGLKETKGAGYIVEGPERIAPAQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTDLWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMKEKGDTGTNPPSHIRQPTTQQDQKEPPAKPKDNKESIPS QEQ ATT                DNEWRHQDKPKQTAGTDNEWR+QDKPKQTSGADNEWRHQDKMKPSTREQPQNKFDRNDDAKRQRMKDHREALPDNNRRRQRSPQPDHRRHYDNQKEQKPRERNKEKSKEKNQ   PPPPAAKLLEDIFRKTVTQPAIYWLPVANEKKQEPIKKIKEAVKVQ
Sbjct:    1 MSQTETFFLPDGRKTSDLKVNELKKELEKLGKSKSGNKPELLNRLNESFTRSVAEASEIEKENSVSSETQNELNNTNQDENEDISQNDHRTVKCKISRYNVDLDAVDDQIPLNAEVNQSVDALDLYVPIDDSLNITDESIQEERIQVTISRNEETETNDNGDDTRLVETLTTDKRTVICVSNDSENDKPTEIDTEAVTDATNENEPLTVEIEDKSQLVTAEPEPTENEPDEMENIELETQIEMYDVDNIDMDGQMEMYEEHKEEVTNTQDQKDENIIVNIEKDLRETEFLEVGTNEETEEGEVISVPITARLGKRKVKEESKSHSSPKKSKKKGLKETKGAGYIVEGPERIAPAQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTDLWLNKIKSVAYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMKEKGDTGTNPPSHIRQPTTQQDQKEPPAKPKDNKESIPSHQEQVATTDNEWRHQDKSKQTAGADNEWRHQDKPKQTAGTDNEWRHQDKPKQTSGADNEWRHQDKMKPSTREQPQNKFDRNDDAKRQRMKDHREALPDNNRRRQRSPQPDHRRHYDNQKEQKPRERNKEKSKEKNQPPPPPPPAAKLLEDIFRKTVTQPAIYWLPVANEKKQEPIKKIKEAVKVQ 668
The following BLAST results are available for this feature:
BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ACIN18.618e-1533.94apoptotic chromatin condensation inducer 1 [Source... [more]
ACIN19.177e-1533.94apoptotic chromatin condensation inducer 1 [Source... [more]
ACIN19.526e-1533.94apoptotic chromatin condensation inducer 1 [Source... [more]
ACIN19.761e-1533.94apoptotic chromatin condensation inducer 1 [Source... [more]
ACIN11.646e-1433.94apoptotic chromatin condensation inducer 1 [Source... [more]
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BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
acin-11.280e-734.67ACINus (Mammalian Apoptotic Chromatin condensation... [more]
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BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Acn4.974e-1843.40gene:FBgn0263198 transcript:FBtr0336842[more]
Acn4.974e-1843.40gene:FBgn0263198 transcript:FBtr0081145[more]
Acn4.974e-1843.40gene:FBgn0263198 transcript:FBtr0081144[more]
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BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
BX465202.19.061e-1836.13apoptotic chromatin condensation inducer 1a [Sourc... [more]
acin1a9.132e-1836.13apoptotic chromatin condensation inducer 1a [Sourc... [more]
acin1a1.473e-1736.13apoptotic chromatin condensation inducer 1a [Sourc... [more]
acin1a2.213e-1736.13apoptotic chromatin condensation inducer 1a [Sourc... [more]
acin1b8.873e-1536.19apoptotic chromatin condensation inducer 1b [Sourc... [more]
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BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ACIN11.520e-1637.27apoptotic chromatin condensation inducer 1 [Source... [more]
ACIN11.542e-1637.27apoptotic chromatin condensation inducer 1 [Source... [more]
ACIN11.546e-1637.27apoptotic chromatin condensation inducer 1 [Source... [more]
ACIN13.196e-1637.27apoptotic chromatin condensation inducer 1 [Source... [more]
ACIN13.298e-1637.27apoptotic chromatin condensation inducer 1 [Source... [more]
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BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Acin16.537e-1533.94apoptotic chromatin condensation inducer 1 [Source... [more]
Acin17.946e-1533.94apoptotic chromatin condensation inducer 1 [Source... [more]
Acin18.448e-1533.94apoptotic chromatin condensation inducer 1 [Source... [more]
Acin11.396e-1433.94apoptotic chromatin condensation inducer 1 [Source... [more]
Acin11.636e-1433.94apoptotic chromatin condensation inducer 1 [Source... [more]
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BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 2
Match NameE-valueIdentityDescription
sp|Q9UKV3|ACINU_HUMAN4.575e-1433.94Apoptotic chromatin condensation inducer in the nu... [more]
sp|Q9JIX8|ACINU_MOUSE5.909e-1433.94Apoptotic chromatin condensation inducer in the nu... [more]
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BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0X3QB763.081e-3152.89Apoptotic chromatin condensation inducer in the nu... [more]
A0A0X3PJR02.112e-3052.89Uncharacterized protein OS=Schistocephalus solidus... [more]
A0A5K3FM635.558e-2751.28Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A5K3FJH16.587e-2751.28Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A158R9A61.419e-2536.84Uncharacterized protein OS=Taenia asiatica OX=6051... [more]
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BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSAMXT00000021624.21.128e-1638.46pep primary_assembly:Astyanax_mexicanus-2.0:16:691... [more]
acin1b1.189e-1641.76apoptotic chromatin condensation inducer in the nu... [more]
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BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
acin1b9.103e-1733.59apoptotic chromatin condensation inducer in the nu... [more]
ENSORLT00000044127.12.102e-1642.55apoptotic chromatin condensation inducer 1 [Source... [more]
ENSORLT00000015255.24.394e-1642.55apoptotic chromatin condensation inducer 1 [Source... [more]
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BLAST of Apoptotic chromatin condensation inducer in the nucleus vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000027295.10.000e+096.41SMESG000027295.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010510 ID=SMED30010510|Name=Apoptotic chromatin condensation inducer in the nucleus|organism=Schmidtea mediterranea sexual|type=transcript|length=2143bp
GTTTGTTTTAATATATTTATAGAAAATATATCCAAATAAAATGTCTCAAA
CTGAAACGTTTTTCTTACCTGATGGAAGGAAAACCTCTGACTTAAAAGTA
AACGAATTAAAAAAAGAATTAGAGAAATTAGGAAAATCTAAATCTGGAAA
TAAGCCTGAACTATTAAATCGATTAAATGAATCGTTTACTAGAAGTGTAG
CTGAAGCCAGTGAAATTGAAAAAGAAAATTCAGTATCTTCTGAAACTCAG
AATGAGCTCAATAATACTAATCAAGATGAAAACGAAGACATTTCACAAAA
TGATCACAGAACAGTAAAATGTAAAATATCCAGATATAATGTCGATTTAG
ATGCAGTTGATGACCAAATTCCTTTAAATGCGGAAGTAAATCAATCGGTC
GATGCTCTCGATTTGTACGTTCCCATTGATGATTCCTTAAACATTACTGA
TGAATCTATCCAGGAAGAACGAATTCAGGTGACGATATCAAGAAACGAAG
AGACTGAAACAAATGACAACGGAGATGATACAAGATTAGTTGAAACATTA
ACAACTGATAAGAGGACGGTTATTTGTGTCAGTAATGATTCTGAGAATGA
CAAACCGACAGAAATCGACACGGAAGCAGTTACTGACGCCACCAATGAAA
AGGAGCCATTAACTGTTGAGATTGAGGATAAAAGTCAGTTGGTTACCGCC
GAACCAGAACCGACAGAAAATGAACCGGATGAAATGGAAAATATCGAATT
GGAAACGCAAATTGAAATGTACGATGTTGACAATATCGACATGGACGGCC
AAATGGAAATGTATGAGGAGCACAAAGAAGAACTTACAAATACACAAGAT
CAGAAAGATGAAAATATAATTGTTAATATCGAGAAAGATTTGAGAGAAAC
TGAATTTCTAGAAGTTGGAACAAACGAAGAGACTGAGGAAGGAGAAGTGA
TATCAGTTCCAATAACGGCTCGACTCGGTAAACGAAAGGTTAAAGAGGAA
AGCAAGAGTCATTCAAGTCCTAAAAAATCTAAAAAGAAAGGATTAAAAGA
AACAAAAGGAGCTGGTTACATTGTGGAAGGTCCAGAAAGAATCGCACCGG
CACAGAAACCGAAAAATATCGCATCAGATGTGTTGAGGATCGATAATCTT
GTGAGGCCTTTCACATTGATCCAGTTGCAGGACATGCTCGCTCTACAGGG
ATTGGTTACTGATCTTTGGCTAAACAAGATCAAATCAGTGGCCTACGTTC
GGTACACCACGGAATCGGTTGCCAGCAGTGCTCAGGAAACGATTGACGGG
TGCCGCTGGCCGTCGATCAATCCGAAATTGTTGTCGTGTGATTTCGTGTC
GTTGCGGGAAATGGAATGGATGAAAGAGAAGGGGGACACTGGAACCAACC
CGCCTTCTCACATAAGACAACCGACCACACAACAGGACCAAAAGGAACCT
CCGGCGAAGCCGAAGGACAACAAAGAGTCAATTCCTTCCCAACAGGAACA
AGCGGCTACCACTGATAACGAATGGCGTCACCAGGATAAACCGAAACAAA
CGGCTGGCACTGATAACGAATGGCGTTATCAGGATAAACCGAAACAAACG
TCCGGCGCTGATAACGAATGGCGCCATCAGGACAAAATGAAGCCGTCTAC
ACGCGAGCAACCTCAAAACAAGTTTGACAGAAATGATGATGCAAAAAGGC
AGCGAATGAAAGACCATCGAGAAGCGCTTCCTGATAACAACAGGCGCCGC
CAGAGAAGTCCTCAGCCTGATCACCGGCGTCATTACGATAACCAGAAGGA
ACAGAAGCCACGAGAACGGAACAAGGAGAAATCAAAGGAAAAGAATCAGC
CGCCTCCTCCCGCCGCCAAATTATTGGAGGACATTTTCAGGAAAACTGTT
ACACAGCCCGCAATTTATTGGTTACCGGTTGCCAATGAGAAGAAGCAGGA
ACCCATTAAAAAGATTAAAGAGGCAGTGAAGGTCCAGTGATTTTTCCAGC
TGATTGGCCGTTTGCTTCTGAAACAAATTCATCATTAGCCAGCAGATTGG
AGAGCCAGATCCGTTGTGGAGGATGTCAATTTTATATGTAAATTAGTAAT
AAATTTTTGGCTGTTTCATTGTTAAATAAATGCATTTTCAGTT
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protein sequence of SMED30010510-orf-1

>SMED30010510-orf-1 ID=SMED30010510-orf-1|Name=SMED30010510-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=650bp
MSQTETFFLPDGRKTSDLKVNELKKELEKLGKSKSGNKPELLNRLNESFT
RSVAEASEIEKENSVSSETQNELNNTNQDENEDISQNDHRTVKCKISRYN
VDLDAVDDQIPLNAEVNQSVDALDLYVPIDDSLNITDESIQEERIQVTIS
RNEETETNDNGDDTRLVETLTTDKRTVICVSNDSENDKPTEIDTEAVTDA
TNEKEPLTVEIEDKSQLVTAEPEPTENEPDEMENIELETQIEMYDVDNID
MDGQMEMYEEHKEELTNTQDQKDENIIVNIEKDLRETEFLEVGTNEETEE
GEVISVPITARLGKRKVKEESKSHSSPKKSKKKGLKETKGAGYIVEGPER
IAPAQKPKNIASDVLRIDNLVRPFTLIQLQDMLALQGLVTDLWLNKIKSV
AYVRYTTESVASSAQETIDGCRWPSINPKLLSCDFVSLREMEWMKEKGDT
GTNPPSHIRQPTTQQDQKEPPAKPKDNKESIPSQQEQAATTDNEWRHQDK
PKQTAGTDNEWRYQDKPKQTSGADNEWRHQDKMKPSTREQPQNKFDRNDD
AKRQRMKDHREALPDNNRRRQRSPQPDHRRHYDNQKEQKPRERNKEKSKE
KNQPPPPAAKLLEDIFRKTVTQPAIYWLPVANEKKQEPIKKIKEAVKVQ*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003723RNA binding
GO:0000166nucleotide binding
GO:0003676nucleic acid binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR036361SAP_dom_sf
IPR034257Acinus_RRM
IPR035979RBD_domain_sf
IPR003034SAP_dom
IPR032552RSB_motif
IPR012677Nucleotide-bd_a/b_plait_sf
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 251..271
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 53..89
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 315..339
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 453..468
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 63..81
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 490..618
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 446..633
NoneNo IPR availablePANTHERPTHR46589FAMILY NOT NAMEDcoord: 9..656
IPR003034SAP domainSMARTSM00513sap_9coord: 15..49
e-value: 8.8E-6
score: 35.2
IPR003034SAP domainPFAMPF02037SAPcoord: 16..47
e-value: 9.6E-9
score: 34.8
IPR003034SAP domainPROSITEPS50800SAPcoord: 15..49
score: 10.945
IPR032552Acin1, RNSP1-SAP18 binding (RSB) motifPFAMPF16294RSB_motifcoord: 566..656
e-value: 1.3E-12
score: 47.8
IPR036361SAP domain superfamilyGENE3DG3DSA:1.10.720.30coord: 9..64
e-value: 4.9E-8
score: 34.4
IPR036361SAP domain superfamilySUPERFAMILYSSF68906SAP domaincoord: 15..49
IPR034257Acinus, RNA recognition motifCDDcd12432RRM_ACINUcoord: 362..448
e-value: 2.715E-27
score: 103.837
IPR035979RNA-binding domain superfamilySUPERFAMILYSSF54928RNA-binding domain, RBDcoord: 354..425