J domain-containing protein

Overview


Name	J domain-containing protein
Smed ID	SMED30010506
Length (bp)	1752

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of J domain-containing protein (SMED30010506) t-SNE clustered cells

Violin plots show distribution of expression levels for J domain-containing protein (SMED30010506) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of J domain-containing protein (SMED30010506) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for J domain-containing protein (SMED30010506) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30010506

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 16

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
protonephridia	SMED30010506	h1SMcG0014597	dd_Smed_v4_4016_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30010506	h1SMcG0014597	dd_Smed_v4_4016_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30010506	h1SMcG0014597	dd_Smed_v4_4016_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30010506	h1SMcG0014597	dd_Smed_v4_4016_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30010506	h1SMcG0014597	dd_Smed_v4_4016_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010506	h1SMcG0014597	Contig49066	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010506	h1SMcG0014597	Contig49066	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010506	h1SMcG0014597	Contig35167	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010506	h1SMcG0014597	Contig35167	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
whole organism	SMED30010506	h1SMcG0014597	Contig49066	newmark_ests	PMID:27612384 Roberts-Galbraith et al., 2016
whole organism	SMED30010506	h1SMcG0014597	Contig49066	uc_Smed_v2	PMID:27612384 Roberts-Galbraith et al., 2016
whole organism	SMED30010506	h1SMcG0014597	Contig35167	newmark_ests	PMID:27612384 Roberts-Galbraith et al., 2016
whole organism	SMED30010506	h1SMcG0014597	Contig35167	uc_Smed_v2	PMID:27612384 Roberts-Galbraith et al., 2016
head region	SMED30010506	h1SMcG0014597	Contig35167	newmark_ests	PMID:27612384 Roberts-Galbraith et al., 2016
head region	SMED30010506	h1SMcG0014597	Contig35167	uc_Smed_v2	PMID:27612384 Roberts-Galbraith et al., 2016
head region	SMED30010506	h1SMcG0014597	OX_Smed_1.0.01868	ox_Smed_v2	PMID:24238224 Kao et al., 2013

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of J domain-containing protein vs. Ensembl Human
Match: DNAJC3 (DnaJ heat shock protein family (Hsp40) member C3 [Source:HGNC Symbol;Acc:HGNC:9439])

HSP 1 Score: 361.303 bits (926), Expect = 3.106e-118
Identity = 213/471 (45.22%), Postives = 306/471 (64.97%), Query Frame = 2

Query:   83 FVSMSIINKRLTLIS---ILLFNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKP---EDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPF---YQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDR-NRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
             V+   +  RL  +    ++L +L  E +      DV+K+L+ G +LLAAGQL DAL+Q+  AV+GDP+NY+ YYRRATVFLAMGK+K+A+ DL+  + LK +F  AR QR +L LKQGKL EA++D   +L+  P   E+ EAQ  L+   E+      A   + +  +  AI +L+K++E       LRE+RA  ++K G+ +KAI+D + A KL ND+ +   ++S L Y+ G+ + SL E+RECLKLD DHK CF HYK +KKL KLI S ++  +D RY D  +K E++ K+EP    Y   + + +C+C SK  +   AI VC      EP N + + D AEA++ +E YD AI  Y+   E + N+Q+ +EG+++AQ+LLK S+KR+YYKIL V R A K+EI+KAYRKLA ++HPD     + KK AE+KFIDI+ AK+VL+D E R+K+D+GEDPLD E Q 
Sbjct:    1 MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQ 471

[Close]

BLAST of J domain-containing protein vs. Ensembl Human
Match: DNAJC3 (DnaJ heat shock protein family (Hsp40) member C3 [Source:HGNC Symbol;Acc:HGNC:9439])

HSP 1 Score: 320.472 bits (820), Expect = 3.747e-103
Identity = 203/468 (43.38%), Postives = 288/468 (61.54%), Query Frame = 2

Query:   83 FVSMSIINKRLTLIS---ILLFNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPF---YQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRG-DNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
             V+   +  RL  +    ++L +L  E +      DV+K+L+ G +LLAAGQL DAL+Q+  AV+GDP+NY+ YYRRATVFLAMGK+K+A+ DL+  + LK +F  AR QR +L LKQGKL EA++D               K +V + + AE                                 LRE+RA  ++K G+ +KAI+D + A KL ND+ +   ++S L Y+ G+ + SL E+RECLKLD DHK CF HYK +KKL KLI S ++  +D RY D  +K E++ K+EP    Y   + + +C+C SK  +   AI VC      EP N + + D AEA++ +E YD AI  Y+   E + N+Q+ +EG+++AQ+LLK S+KR+YYKIL V R A K+EI+KAYRKLA ++HPD  +  + KK AE+KFIDI+ AK+VL+D E R+K+D+GEDPLD E Q 
Sbjct:    1 MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDF--------------KKVVCVWD-AE---------------------------------LRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQ 420

[Close]

BLAST of J domain-containing protein vs. Ensembl Human
Match: DNAJC7 (DnaJ heat shock protein family (Hsp40) member C7 [Source:HGNC Symbol;Acc:HGNC:12392])

HSP 1 Score: 109.383 bits (272), Expect = 1.071e-24
Identity = 106/416 (25.48%), Postives = 195/416 (46.88%), Query Frame = 2

Query:  251 YDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYN---DCITKA-----ENLKKSEPFYQSFAYQYLCN---CHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDN---KKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPE 1456
            Y KA++  P N   Y  RA   + +G+ + A+ D   S+ L  +F+    +    +L  G    A       L+   ++ +AQ+   N   + E  ++A+T +E   F   +  +++ +E        + ++A      G   +A +     +++ + + D +      LY     ++++    + L++ PDH+      +  K L         A K+  Y    +  T+A      N+K +   Y        CN    +SK+ +   AIE C  A   +          A+ ++  E Y+ A+  Y+KV +++   +  K+ +K AQ  LK SK+++YYKIL V + A++ EI KAYRK A  +HPDR+ G +   +K  E+KF ++ +A  +L+D +K+ +YD+G+D LD E
Sbjct:   51 YTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLY--------CNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEH-KQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQD-LDEE 456

[Close]

BLAST of J domain-containing protein vs. Ensembl Human
Match: DNAJC7 (DnaJ heat shock protein family (Hsp40) member C7 [Source:HGNC Symbol;Acc:HGNC:12392])

HSP 1 Score: 105.145 bits (261), Expect = 1.456e-23
Identity = 103/408 (25.25%), Postives = 190/408 (46.57%), Query Frame = 2

Query:  275 PNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYN---DCITKA-----ENLKKSEPFYQSFAYQYLCN---CHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDN---KKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPE 1456
            P N   Y  RA   + +G+ + A+ D   S+ L  +F+    +    +L  G    A       L+   ++ +AQ+   N   + E  ++A+T +E   F   +  +++ +E        + ++A      G   +A +     +++ + + D +      LY     ++++    + L++ PDH+      +  K L         A K+  Y    +  T+A      N+K +   Y        CN    +SK+ +   AIE C  A   +          A+ ++  E Y+ A+  Y+KV +++   +  K+ +K AQ  LK SK+++YYKIL V + A++ EI KAYRK A  +HPDR+ G +   +K  E+KF ++ +A  +L+D +K+ +YD+G+D LD E
Sbjct:    3 PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLY--------CNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEH-KQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQD-LDEE 400

[Close]

BLAST of J domain-containing protein vs. Ensembl Human
Match: DNAJC7 (DnaJ heat shock protein family (Hsp40) member C7 [Source:HGNC Symbol;Acc:HGNC:12392])

HSP 1 Score: 105.145 bits (261), Expect = 1.456e-23
Identity = 103/408 (25.25%), Postives = 190/408 (46.57%), Query Frame = 2

Query:  275 PNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYN---DCITKA-----ENLKKSEPFYQSFAYQYLCN---CHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDN---KKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPE 1456
            P N   Y  RA   + +G+ + A+ D   S+ L  +F+    +    +L  G    A       L+   ++ +AQ+   N   + E  ++A+T +E   F   +  +++ +E        + ++A      G   +A +     +++ + + D +      LY     ++++    + L++ PDH+      +  K L         A K+  Y    +  T+A      N+K +   Y        CN    +SK+ +   AIE C  A   +          A+ ++  E Y+ A+  Y+KV +++   +  K+ +K AQ  LK SK+++YYKIL V + A++ EI KAYRK A  +HPDR+ G +   +K  E+KF ++ +A  +L+D +K+ +YD+G+D LD E
Sbjct:    3 PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLY--------CNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEH-KQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQD-LDEE 400

[Close]

BLAST of J domain-containing protein vs. Ensembl Celegans
Match: dnj-7 (DNaJ domain (Prokaryotic heat shock protein) [Source:UniProtKB/TrEMBL;Acc:P91189])

HSP 1 Score: 305.064 bits (780), Expect = 3.911e-97
Identity = 184/451 (40.80%), Postives = 267/451 (59.20%), Query Frame = 2

Query:  128 ILLFNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPF--YQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGD--NKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQHQ 1468
            ++L++     +      +V K+L+ G++ LA  Q  DAL QY  A+E DP +Y   YRRAT +LAMG+ K+AI DL   L LKP+F  AR QR N+ LKQG+L  A+ D N++L H   + + Q+    I +  +     K+ Y          Y+N ++E       L  MRA    + G+ +KAI+D R   KLS D  D +   SKLLY  G+ ++SL  IRECLKL+PDHK C+  YK ++K+VK + S++   ++  +  C+ + +   K +P    Q   ++    C  +      AI  C     ++P + D++C+ AEA I DE+YDSAI  YQK  E + +++ AKEG++ A++L   + KR+YYKIL V R A+K+EI KAYRKLA ++HPD N  D   KK AE+KFIDI+ AK+VL D EKR+++D G DPLDPE Q Q
Sbjct:    8 LILWSSLFASTFAGTAEEVAKHLELGSQFLARAQFADALTQYHAAIELDPKSYQAIYRRATTYLAMGRGKAAIVDLERVLELKPDFYGARIQRGNILLKQGELEAAEADFNIVLNHDSSNNDVQEKTALIEQHRQLRHQIKSAYAGGDCATVEEYINHIIEIQVWDASLYRMRAKCLEERGELKKAIHDMRIVSKLSTDSTDTMFETSKLLYTVGDLEESLNVIRECLKLNPDHKSCYPFYKKLRKVVKSLESMKKKVENSDWMACLEEGQKTMKFDPTPSVQLNVFRITNRCQREAGHISEAIAECNEILNDDPSDADILCERAEAHILDEDYDSAIEDYQKATEVNPDHREAKEGLEHAKRLKTQAGKRDYYKILGVKRNASKREITKAYRKLAQKWHPD-NFSDEEEKKKAEKKFIDIAAAKEVLQDEEKRRQFDQGVDPLDPEAQRQ 457

[Close]

BLAST of J domain-containing protein vs. Ensembl Celegans
Match: dnj-28 (DNaJ domain (Prokaryotic heat shock protein) [Source:UniProtKB/TrEMBL;Acc:Q9N3E0])

HSP 1 Score: 260.766 bits (665), Expect = 5.586e-80
Identity = 155/408 (37.99%), Postives = 237/408 (58.09%), Query Frame = 2

Query:  251 YDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQH---KPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENL--KKSEPFYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNR-GDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPE 1456
            Y KA+E +P  Y   +RRAT +LA G++K  + DL   L  KP+F  AR QRA++ LK G+L  A  D   L+ H   +    EAQ+ L  I E    +EM K++  N    + I     ++ET      L   RA  Y+     + AI+D ++A KLS+D+ + +  +S+L Y+  +   SL  IRECLKL+PDHK C+  YK +KK+VK ++S++ + + + +  C+   E L  K  E   +   ++ +C C+ +      AI+ C      +  + + +   AEA++ADE YD AI+ Y+K  E D++N   + G  +A++  +   KR+YYKIL V R A K+EI KAYRK+A ++HPD  +    KK AE+KFIDI+ AK+VL++ EKR+ +DNG+DPLD E
Sbjct:   47 YHKAIELNPTMYQAIFRRATTYLAFGRSKPGLADLDTVLSQKPDFAGARQQRASVLLKMGQLERAAADFRYLIDHSASQETSQEAQEKLELISEHINQVEMLKSWITNGDCNNVIESTTHLLETQPWDASLYIYRAKCYVAEDKVKSAIHDMKHAAKLSSDNTELLFEMSELEYKVADVRDSLGSIRECLKLNPDHKKCYTSYKSLKKIVKSLDSMKASIEQQEWTKCLETGEKLLEKNEEIPIRMNIFRLMCQCNREDGNLGEAIQQCTRVLEFDDSDVETLIQRAEAYMADEEYDMAIADYEKAEEWDSSNDAVRTGKDQAKRAKELVGKRDYYKILGVRRNANKREITKAYRKMAQKWHPDNFQDEKEKKKAEKKFIDIAAAKEVLSNEEKRRAFDNGQDPLDSE 454

[Close]

BLAST of J domain-containing protein vs. Ensembl Celegans
Match: dnj-22 (DNaJ domain (Prokaryotic heat shock protein) [Source:UniProtKB/TrEMBL;Acc:O17002])

HSP 1 Score: 69.707 bits (169), Expect = 6.876e-13
Identity = 38/77 (49.35%), Postives = 53/77 (68.83%), Query Frame = 2

Query: 1235 NYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
            N YKIL++ +  T KEI KAYR    ++HPD+N  DNK+ AER+FI+  +A D L D EKR++YDN E+ +   Q+H
Sbjct:    8 NPYKILHLEKGCTDKEIQKAYRAQCLKWHPDKNL-DNKEEAERRFIEAKEAFDFLYDKEKREEYDNREERIRMAQEH 83

[Close]

BLAST of J domain-containing protein vs. Ensembl Celegans
Match: dnj-20 (DnaJ homolog dnj-20 [Source:UniProtKB/Swiss-Prot;Acc:Q8MPX3])

HSP 1 Score: 67.3958 bits (163), Expect = 8.032e-12
Identity = 38/73 (52.05%), Postives = 50/73 (68.49%), Query Frame = 2

Query: 1232 RNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYD-NGEDPL 1447
            R++YKIL V + A   +I KAYRKLA E HPDRN+ D  + A  KF D+S A +VL+D EKR  YD +GE+ +
Sbjct:   23 RDFYKILGVAKNANANQIKKAYRKLAKELHPDRNQDD--EMANEKFQDLSSAYEVLSDKEKRAMYDRHGEEGV 93

[Close]

BLAST of J domain-containing protein vs. Ensembl Celegans
Match: dnj-13 (DNaJ domain (Prokaryotic heat shock protein) [Source:UniProtKB/TrEMBL;Acc:Q20774])

HSP 1 Score: 66.2402 bits (160), Expect = 1.387e-11
Identity = 35/73 (47.95%), Postives = 53/73 (72.60%), Query Frame = 2

Query: 1232 RNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDN-GEDPL 1447
            ++YYK+L + + AT  EI KAYRK+A +YHPD+N+   +  AE KF +I++A DVL+D +K++ YD  GE+ L
Sbjct:    3 KDYYKVLGISKGATDDEIKKAYRKMALKYHPDKNK---EAGAENKFKEIAEAYDVLSDDKKKKIYDQFGEEGL 72

[Close]

BLAST of J domain-containing protein vs. Ensembl Fly
Match: P58IPK (gene:FBgn0037718 transcript:FBtr0082074)

HSP 1 Score: 327.02 bits (837), Expect = 2.001e-105
Identity = 176/434 (40.55%), Postives = 277/434 (63.82%), Query Frame = 2

Query:  164 TSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSFAYQ---YLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPE 1456
            T+ P D++ +L+ G   LA GQL DAL  Y  AVEGD NNYL  ++R TV+LA+GKT+ A++D S  L LKP+F+ AR QR  +++K G+  +A +D + +LQ +P +    +    +    E   + +   + +  ++AI  + +++E +  +   R+ R+++Y+   D   AI D R   +L+ D  +G  ++++LLY  G+A  +L EIRECLK DP+HK CF  YK ++K+ K + + + A ++K + +CI   E + ++EP      Y+    LC C++   +   A++ C+ A  +  ++  V CD A+A +  E YD AI  +Q  L+ + +N RAKEG++RA+KL K S++R+YYKIL V R+A+K+EI+KAYRK A ++HPD  R + KK AE+KFIDI+ AK+VLTD EKR+++DNGEDPLDPE
Sbjct:   37 TASPADIENHLELGKEFLARGQLSDALTHYHAAVEGDANNYLTLFKRGTVYLALGKTRFAVQDFSRVLELKPDFMAARIQRGVVHMKSGEYEQAIQDFDQVLQEEPNNGLVLEHYSRLAPAQEQWVLVQQLIQYSDHQNAIPMITQLLEISPWAVPFRQARSDAYIAINDPLLAIADLRQVNRLTQDSTEGHYKIAQLLYTIGHATNALKEIRECLKFDPEHKLCFPFYKKLRKVEKQLVNAEQAREEKHFAECIAAGEAVLRNEPEETMIRYEGHKVLCTCYTGDEQFGKALQQCKEA-LDIMKDAQVYCDRADALLGTEMYDDAIHSFQAALDLEESNTRAKEGIQRAKKLQKQSERRDYYKILGVKRSASKQEIVKAYRKAAQKWHPDNFRDEEKKVAEKKFIDIAAAKEVLTDPEKRRQFDNGEDPLDPE 469

[Close]

BLAST of J domain-containing protein vs. Ensembl Fly
Match: Tpr2 (gene:FBgn0032586 transcript:FBtr0080867)

HSP 1 Score: 104.76 bits (260), Expect = 1.151e-23
Identity = 98/411 (23.84%), Postives = 183/411 (44.53%), Query Frame = 2

Query:  251 YDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLL--LQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSFAYQYLCN---CHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRN---RGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQ 1459
            Y  A+   P++   Y  RA  ++ +    SA+ D  +++ + P F  A  + A   L  G +   ++ + ++  L      V A++         EA   A   Y+   + + + YL+  ++        R ++A      G   +A++     +KL     D I      LY T N D+ ++     L LDPDH    +     K+L ++  +     K  RY +      +  K +   +    + L N    ++++   + A+  C        Q    +   A  +   E ++ +++ Y+  L+ +   +  K  ++ A+  LK SK+++YYKIL + R A+  EI KAYRK A  +HPDR+     + +K  E KF ++ +A  +L+DA K+ +YD+G+D  + EQ
Sbjct:   28 YTDAISLCPDSAAYYGNRAACYMMLLNYNSALTDARHAIRIDPGFEKAYVRVAKCCLALGDIIGTEQAVKMVNELNSLSTAVAAEQTAAQKLRQLEATIQAN--YDTKSYRNVVFYLDSALKLAPACLKYRLLKAECLAFLGRCDEALDIAVSVMKLDTTSADAIYVRGLCLYYTDNLDKGILHFERALTLDPDHYKSKQMRSKCKQLKEMKENGNMLFKSGRYREAHVIYTDALKIDEHNKDINSKLLYNRALVNTRIGNLREAVADCNRVLELNSQYLKALLLRARCYNDLEKFEESVADYETALQLEKTPE-IKRMLREAKFALKKSKRKDYYKILGIGRNASDDEIKKAYRKKALVHHPDRHANSSAEERKEEELKFKEVGEAYAILSDAHKKSRYDSGQDIEEQEQ 435

[Close]

BLAST of J domain-containing protein vs. Ensembl Fly
Match: Tpr2 (gene:FBgn0032586 transcript:FBtr0333488)

HSP 1 Score: 104.76 bits (260), Expect = 1.151e-23
Identity = 98/411 (23.84%), Postives = 183/411 (44.53%), Query Frame = 2

Query:  251 YDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLL--LQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSFAYQYLCN---CHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRN---RGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQ 1459
            Y  A+   P++   Y  RA  ++ +    SA+ D  +++ + P F  A  + A   L  G +   ++ + ++  L      V A++         EA   A   Y+   + + + YL+  ++        R ++A      G   +A++     +KL     D I      LY T N D+ ++     L LDPDH    +     K+L ++  +     K  RY +      +  K +   +    + L N    ++++   + A+  C        Q    +   A  +   E ++ +++ Y+  L+ +   +  K  ++ A+  LK SK+++YYKIL + R A+  EI KAYRK A  +HPDR+     + +K  E KF ++ +A  +L+DA K+ +YD+G+D  + EQ
Sbjct:   28 YTDAISLCPDSAAYYGNRAACYMMLLNYNSALTDARHAIRIDPGFEKAYVRVAKCCLALGDIIGTEQAVKMVNELNSLSTAVAAEQTAAQKLRQLEATIQAN--YDTKSYRNVVFYLDSALKLAPACLKYRLLKAECLAFLGRCDEALDIAVSVMKLDTTSADAIYVRGLCLYYTDNLDKGILHFERALTLDPDHYKSKQMRSKCKQLKEMKENGNMLFKSGRYREAHVIYTDALKIDEHNKDINSKLLYNRALVNTRIGNLREAVADCNRVLELNSQYLKALLLRARCYNDLEKFEESVADYETALQLEKTPE-IKRMLREAKFALKKSKRKDYYKILGIGRNASDDEIKKAYRKKALVHHPDRHANSSAEERKEEELKFKEVGEAYAILSDAHKKSRYDSGQDIEEQEQ 435

[Close]

BLAST of J domain-containing protein vs. Ensembl Fly
Match: Tpr2 (gene:FBgn0032586 transcript:FBtr0333486)

HSP 1 Score: 104.76 bits (260), Expect = 1.503e-23
Identity = 98/411 (23.84%), Postives = 183/411 (44.53%), Query Frame = 2

Query:  251 YDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLL--LQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSFAYQYLCN---CHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRN---RGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQ 1459
            Y  A+   P++   Y  RA  ++ +    SA+ D  +++ + P F  A  + A   L  G +   ++ + ++  L      V A++         EA   A   Y+   + + + YL+  ++        R ++A      G   +A++     +KL     D I      LY T N D+ ++     L LDPDH    +     K+L ++  +     K  RY +      +  K +   +    + L N    ++++   + A+  C        Q    +   A  +   E ++ +++ Y+  L+ +   +  K  ++ A+  LK SK+++YYKIL + R A+  EI KAYRK A  +HPDR+     + +K  E KF ++ +A  +L+DA K+ +YD+G+D  + EQ
Sbjct:   42 YTDAISLCPDSAAYYGNRAACYMMLLNYNSALTDARHAIRIDPGFEKAYVRVAKCCLALGDIIGTEQAVKMVNELNSLSTAVAAEQTAAQKLRQLEATIQAN--YDTKSYRNVVFYLDSALKLAPACLKYRLLKAECLAFLGRCDEALDIAVSVMKLDTTSADAIYVRGLCLYYTDNLDKGILHFERALTLDPDHYKSKQMRSKCKQLKEMKENGNMLFKSGRYREAHVIYTDALKIDEHNKDINSKLLYNRALVNTRIGNLREAVADCNRVLELNSQYLKALLLRARCYNDLEKFEESVADYETALQLEKTPE-IKRMLREAKFALKKSKRKDYYKILGIGRNASDDEIKKAYRKKALVHHPDRHANSSAEERKEEELKFKEVGEAYAILSDAHKKSRYDSGQDIEEQEQ 449

[Close]

BLAST of J domain-containing protein vs. Ensembl Fly
Match: Tpr2 (gene:FBgn0032586 transcript:FBtr0080866)

HSP 1 Score: 104.375 bits (259), Expect = 2.340e-23
Identity = 98/411 (23.84%), Postives = 183/411 (44.53%), Query Frame = 2

Query:  251 YDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLL--LQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSFAYQYLCN---CHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRN---RGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQ 1459
            Y  A+   P++   Y  RA  ++ +    SA+ D  +++ + P F  A  + A   L  G +   ++ + ++  L      V A++         EA   A   Y+   + + + YL+  ++        R ++A      G   +A++     +KL     D I      LY T N D+ ++     L LDPDH    +     K+L ++  +     K  RY +      +  K +   +    + L N    ++++   + A+  C        Q    +   A  +   E ++ +++ Y+  L+ +   +  K  ++ A+  LK SK+++YYKIL + R A+  EI KAYRK A  +HPDR+     + +K  E KF ++ +A  +L+DA K+ +YD+G+D  + EQ
Sbjct:   72 YTDAISLCPDSAAYYGNRAACYMMLLNYNSALTDARHAIRIDPGFEKAYVRVAKCCLALGDIIGTEQAVKMVNELNSLSTAVAAEQTAAQKLRQLEATIQAN--YDTKSYRNVVFYLDSALKLAPACLKYRLLKAECLAFLGRCDEALDIAVSVMKLDTTSADAIYVRGLCLYYTDNLDKGILHFERALTLDPDHYKSKQMRSKCKQLKEMKENGNMLFKSGRYREAHVIYTDALKIDEHNKDINSKLLYNRALVNTRIGNLREAVADCNRVLELNSQYLKALLLRARCYNDLEKFEESVADYETALQLEKTPE-IKRMLREAKFALKKSKRKDYYKILGIGRNASDDEIKKAYRKKALVHHPDRHANSSAEERKEEELKFKEVGEAYAILSDAHKKSRYDSGQDIEEQEQ 479

[Close]

BLAST of J domain-containing protein vs. Ensembl Zebrafish
Match: dnajc3b (DnaJ (Hsp40) homolog, subfamily C, member 3b [Source:ZFIN;Acc:ZDB-GENE-000831-4])

HSP 1 Score: 370.548 bits (950), Expect = 4.440e-122
Identity = 203/445 (45.62%), Postives = 291/445 (65.39%), Query Frame = 2

Query:  140 NLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEP---FYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGD-NKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQ 1462
            +L ++  + + P +++ +L+ G +LLAAGQL +AL+ Y  AVEGD  NYL YY+RATVFLAMGK+KSA+ DL+ ++ LKP+F+ AR QR N+ LKQG   EA+ED   +L H P+  EA   L+   ++    E A   +       A+  L  V+E +      RE+RA  Y++ G+ +KAI D   A +L  D+R   L+LS+L Y  G    SL ++RECLKLD D K+CF  YK +KKL K ++S ++   ++R+ + I K E++ ++EP   FY + A +  C C  K+  A+ A+++C  AH  EPQN  ++ D AEA+I  + Y+ A+  YQ+  E D  NQ  +EG+ RA KLLK S+KR+YYKIL V R+A K+EI+KAYRKLA ++HPD  + + +KK AE+KFIDI+ AK+VLTD E RQK+D+GEDPLDPE Q
Sbjct:   28 DLQLDGVLGATPVEIEHHLEMGRKLLAAGQLAEALSHYHSAVEGDSKNYLTYYKRATVFLAMGKSKSALPDLTQAIQLKPDFLAARLQRGNILLKQGSTQEAREDFQAVLNHSPDHEEAHDQLLKADKLESLQEEAHEAHRRGDCRIAVQVLEHVIELSPWDPESRELRAECYIQLGEPRKAIMDLTPASRLRADNRAAFLKLSQLHYSLGEHHDSLNQVRECLKLDQDDKECFALYKQVKKLSKQLDSAEELISEQRFQEAIEKYESVMRTEPNVAFYTNKAKERTCFCLVKMKSAEEAVDICSEAHQREPQNIHILRDRAEAYILMQEYEKAVEDYQEAREFDQENQELREGLDRAHKLLKISRKRDYYKILGVSRSANKQEIIKAYRKLAQQWHPDNFQSEADKKEAEKKFIDIASAKEVLTDPEMRQKFDSGEDPLDPENQ 472

[Close]

BLAST of J domain-containing protein vs. Ensembl Zebrafish
Match: dnajc3a (DnaJ (Hsp40) homolog, subfamily C, member 3a [Source:ZFIN;Acc:ZDB-GENE-030131-1264])

HSP 1 Score: 359.762 bits (922), Expect = 6.529e-118
Identity = 211/465 (45.38%), Postives = 300/465 (64.52%), Query Frame = 2

Query:   98 IINKRLTLISILL--FNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKP---EDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSF---AYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNR-GDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
            + +K L+ +  LL   +L  E       G V+ +L+ G +LLAAGQL DAL+ +  AV+G+P NY+ +YRRATV+LAMGK+KSA+ DLS  + LKP+F  AR QR NL LK GKL EA+ D   +L+  P   E+ EAQ  L    EI   +  A++ +++  +  A  +L+ +++T       REMRA  +++ G+  KAI+D + A KL +D+     +LS + Y+ G+ + SL E+RECLKLD DHK CF HYK +KKL K I S ++  + ++Y+D ++K E++ K+EP    F   A + +C+C SK  +   AI VC      +PQN + + D AEA + D+ Y+ AI  +Q   E   N+++ KEG++RAQ+LLK SKKR+YYKIL V RTA KKEILKAYRKLA ++HPD  +  + KK AE+KFIDI+ AK+VLTD E R K+D GEDP+DPE Q 
Sbjct:    7 VAHKLLSYVPFLLVLIDLRYEGVNGGKDGGVENHLEMGKKLLAAGQLADALSHFHAAVDGEPKNYMAFYRRATVYLAMGKSKSALPDLSKVIELKPDFTSARLQRGNLLLKHGKLDEAESDFKKVLKSNPSSREEQEAQSQLKKSDEIQRLVSQAQSDFKHREYSSAASHLDIIIDTCVWDVDSREMRAECFIQMGELGKAISDLKAASKLKSDNTQAFYKLSTIYYDLGDHEMSLNEVRECLKLDQDHKQCFSHYKQVKKLNKQIQSAEELIQQEKYSDAVSKYESVMKTEPNVPHFTLNAKERMCHCLSKDQQTARAISVCSEVLNTDPQNVNALKDRAEALLQDDQYEEAIKDFQSAKEYSENDRQIKEGLERAQRLLKQSKKRDYYKILGVKRTAQKKEILKAYRKLAQQWHPDNFQDAEEKKKAEKKFIDIAQAKEVLTDPEMRSKFDQGEDPMDPESQQ 471

[Close]

Query:   98 IINKRLTLISILL--FNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKP---EDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSF---AYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNR-GDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
            + +K L+ +  LL   +L  E       G V+ +L+ G +LLAAGQL DAL+ +  AV+G+P NY+ +YRRATV+LAMGK+KSA+ DLS  + LKP+F  AR QR NL LK GKL EA+ D   +L+  P   E+ EAQ  L    EI   +  A++ +++  +  A  +L+ +++T       REMRA  +++ G+  KAI+D + A KL +D+     +LS + Y+ G+ + SL E+RECLKLD DHK CF HYK +KKL K I S ++  + ++Y+D ++K E++ K+EP    F   A + +C+C SK  +   AI VC      +PQN + + D AEA + D+ Y+ AI  +Q   E   N+++ KEG++RAQ+LLK SKKR+YYKIL V RTA KKEILKAYRKLA ++HPD  +  + KK AE+KFIDI+ AK+VLTD E R K+D GEDP+DPE Q 
Sbjct:    7 VAHKLLSYVPFLLVLIDLRYEGVNGGKDGGVENHLEMGKKLLAAGQLADALSHFHAAVDGEPKNYMAFYRRATVYLAMGKSKSALPDLSKVIELKPDFTSARLQRGNLLLKHGKLDEAESDFKKVLKSNPSSREEQEAQSQLKKSDEIQRLVSQAQSDFKHREYSSAASHLDIIIDTCVWDVDSREMRAECFIQMGELGKAISDLKAASKLKSDNTQAFYKLSTIYYDLGDHEMSLNEVRECLKLDQDHKQCFSHYKQVKKLNKQIQSAEELIQQEKYSDAVSKYESVMKTEPNVPHFTLNAKERMCHCLSKDQQTARAISVCSEVLNTDPQNVNALKDRAEALLQDDQYEEAIKDFQSAKEYSENDRQIKEGLERAQRLLKQSKKRDYYKILGVKRTAQKKEILKAYRKLAQQWHPDNFQDAEEKKKAEKKFIDIAQAKEVLTDPEMRSKFDQGEDPMDPESQQ 471

[Close]

BLAST of J domain-containing protein vs. Ensembl Zebrafish
Match: dnajc7 (DnaJ (Hsp40) homolog, subfamily C, member 7 [Source:ZFIN;Acc:ZDB-GENE-040426-2483])

HSP 1 Score: 116.316 bits (290), Expect = 3.894e-27
Identity = 106/411 (25.79%), Postives = 197/411 (47.93%), Query Frame = 2

Query:  251 YDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDC---ITKA-----ENLKKSEPFYQSFAYQYLCN---CHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDN---KKAAERKFIDISDAKDVLTDAEKRQKYDNGED 1441
            Y KA++  P N   Y  RA   + + + + A+ED   ++ L  +F+    +    +L  G    A   +  +L+ +P++ +AQ+ + N   I E   MA+  +E   F   +  +++V+++ +     + ++A      G   +A +     +++ + + D +      LY     D+++    + L++ PDH+      +  K L         A K+  Y +     T+A      N+K +   Y        CN     SK+++ + AIE C  A   +          A+ ++  E Y+ A+  Y+KV +++   +  K  +K AQ  LK SK+++YYK+L V + AT+ EI KAYRK A  +HPDR+ G +   +K  E+KF ++ +A  VL+D +K+ +YD+G D
Sbjct:   80 YTKAIDLCPKNASYYGNRAATLMMLSRYREALEDSQQAVRLDDSFMKGHMREGKCHLLLGNAMAAIRCLQKVLEREPDNSQAQQEMKNAESILEYERMAEISFEKRDFRMVVFCMDRVLDSASACHRFKVLKAECLALLGRYPEAQSVASDILRMDSTNGDALYVRGLCLYYEDCIDKAVQFFVQALRMAPDHEKARLACRNAKALKAKKEEGNKAFKEGSYEEAYELYTEALTIDPNNIKTNAKLY--------CNRATVGSKLNKLEQAIEDCTKAIKLDETYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEH-KNLLKNAQLELKKSKRKDYYKVLGVDKNATEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTVLSDPKKKTRYDSGHD 481

[Close]

BLAST of J domain-containing protein vs. Ensembl Zebrafish
Match: dnajc7 (DnaJ (Hsp40) homolog, subfamily C, member 7 [Source:ZFIN;Acc:ZDB-GENE-040426-2483])

HSP 1 Score: 115.546 bits (288), Expect = 4.557e-27
Identity = 106/411 (25.79%), Postives = 197/411 (47.93%), Query Frame = 2

Query:  251 YDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDC---ITKA-----ENLKKSEPFYQSFAYQYLCN---CHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDN---KKAAERKFIDISDAKDVLTDAEKRQKYDNGED 1441
            Y KA++  P N   Y  RA   + + + + A+ED   ++ L  +F+    +    +L  G    A   +  +L+ +P++ +AQ+ + N   I E   MA+  +E   F   +  +++V+++ +     + ++A      G   +A +     +++ + + D +      LY     D+++    + L++ PDH+      +  K L         A K+  Y +     T+A      N+K +   Y        CN     SK+++ + AIE C  A   +          A+ ++  E Y+ A+  Y+KV +++   +  K  +K AQ  LK SK+++YYK+L V + AT+ EI KAYRK A  +HPDR+ G +   +K  E+KF ++ +A  VL+D +K+ +YD+G D
Sbjct:   36 YTKAIDLCPKNASYYGNRAATLMMLSRYREALEDSQQAVRLDDSFMKGHMREGKCHLLLGNAMAAIRCLQKVLEREPDNSQAQQEMKNAESILEYERMAEISFEKRDFRMVVFCMDRVLDSASACHRFKVLKAECLALLGRYPEAQSVASDILRMDSTNGDALYVRGLCLYYEDCIDKAVQFFVQALRMAPDHEKARLACRNAKALKAKKEEGNKAFKEGSYEEAYELYTEALTIDPNNIKTNAKLY--------CNRATVGSKLNKLEQAIEDCTKAIKLDETYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEH-KNLLKNAQLELKKSKRKDYYKVLGVDKNATEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTVLSDPKKKTRYDSGHD 437

[Close]

BLAST of J domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000019480.1 (dnaJ homolog subfamily C member 3 like [Source:NCBI gene;Acc:734020])

HSP 1 Score: 372.859 bits (956), Expect = 5.701e-123
Identity = 210/448 (46.88%), Postives = 294/448 (65.62%), Query Frame = 2

Query:  131 LLFNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSF---AYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRG-DNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQ 1462
            ++ +L ++  + ++  +++ +L+ G +LLAAGQL +AL+ Y  AV+GDPNNYL YY+RA V+LAMGK +SA+ DLS ++ LKP+F+ AR QR N+ LKQG + EA+ED   +LQ  P + EAQ  L  + E+  ++  A   YE   +  AI  L KV+E +      RE+RA  YL  G+   A+ D +   KL ND+R   L+LSKL Y  G   +SL  +RECLKLD D KDCF HYK +KKL + ++  ++  +++RY D I K E   K+EP  + +   A + +C+C SK    + AI VC  AH  +PQN  ++ D AEA+I +E Y+ A+  +Q+  E D  N+  KEG++RAQKLLK SKKR+YYKIL V R A K+E++KAYRKLA ++HPD  +  + KK AE+KFIDI+ AK+VLTD E RQK D GEDPLDPE Q
Sbjct:   20 VILDLQLDGLLAANHAEIEGHLEMGRKLLAAGQLAEALSHYHAAVDGDPNNYLTYYKRAAVYLAMGKFRSALPDLSRAIQLKPDFLAARLQRGNILLKQGDVQEAREDFLSVLQSSPTNEEAQNQLERVKEVESSMGGASEAYERRDYYGAIALLEKVIEFSPWDPSARELRAECYLLVGELSNAVQDLKPTTKLRNDNRAAFLKLSKLYYSMGEHGESLSHVRECLKLDQDDKDCFSHYKQVKKLSRQLDMAEEFIQEQRYEDAIEKYEASIKTEPRVEEYSRRAKERICHCLSKSQRTEEAISVCTEAHERDPQNPLILRDRAEAYILNEEYEKAVEDFQQAKELDGENEEMKEGLERAQKLLKQSKKRDYYKILGVKRNANKQEVIKAYRKLAQQWHPDNFQSEEEKKEAEKKFIDIAAAKEVLTDPEMRQKVDAGEDPLDPENQ 467

[Close]

BLAST of J domain-containing protein vs. Ensembl Xenopus
Match: gask1b (golgi associated kinase 1B [Source:Xenbase;Acc:XB-GENE-960860])

HSP 1 Score: 372.474 bits (955), Expect = 1.174e-122
Identity = 219/471 (46.50%), Postives = 304/471 (64.54%), Query Frame = 2

Query:   83 FVSMSI-INKRLTLISILL--FNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKP---EDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSE---PFYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNR-GDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
             VS+S    K L+    LL  F+L  E        DVDK+L+ G +LLAAGQL DAL+ +  A++GDP+NY+ YYRRATV+LAMGK+K+AI DLS  + LKP+F  AR QR +L LKQGKL EA+ED   +L+  P   E+ EA   L+   EI          Y+   +  A  YLN V+ET      +RE+RA  Y+  G+  KAI+D + A KL +D+ +   ++SK+ Y+ G+ + SL EIRECLKLDPDHK+CF HYK +KKL K I + ++   + RY D + K E + K+E   P+Y +   +  C+C+SK  ++  AI VC      EP N + + D AEA+I +E Y+ AI  Y+   +++ N+++ +EG+ +AQKLLK S+KR+YYKIL V R A K+EI+KAYRKLA ++HPD  +  + KK AE+KFIDI+ AK+VLTD EKR ++D GEDPLDPE Q 
Sbjct:    1 MVSLSASAQKLLSFFPFLLVLFDLQYEGVECGINADVDKHLEMGKKLLAAGQLADALSHFHSAIDGDPDNYVAYYRRATVYLAMGKSKAAIPDLSKVIELKPDFTSARVQRGHLLLKQGKLDEAEEDFKKVLKSNPNEQEEKEANAQLLKSSEIQSMRSQGIAAYKEGDYSTAETYLNFVLETCIWDAEIRELRAECYISQGEPGKAISDLKAASKLKSDNTNAFYKVSKIYYQLGDHEMSLSEIRECLKLDPDHKECFSHYKQVKKLNKQIQAAEELIHEGRYEDALPKYEGILKTEPNVPYYSALVQERSCHCYSKSQQSTEAIRVCTEFLQQEPNNVNALKDRAEAYILEEMYEEAIRDYETAQQNNENDKQIREGLDKAQKLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLAQQWHPDNFQDEEEKKKAEKKFIDIASAKEVLTDPEKRSRFDAGEDPLDPESQQ 471

[Close]

BLAST of J domain-containing protein vs. Ensembl Xenopus
Match: gask1b (golgi associated kinase 1B [Source:Xenbase;Acc:XB-GENE-960860])

HSP 1 Score: 368.237 bits (944), Expect = 4.195e-121
Identity = 209/437 (47.83%), Postives = 291/437 (66.59%), Query Frame = 2

Query:  176 GDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKP---EDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSE---PFYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNR-GDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
             DVDK+L+ G +LLAAGQL DAL+ +  A++GDP+NY+ YYRRATV+LAMGK+K+AI DLS  + LKP+F  AR QR +L LKQGKL EA+ED   +L+  P   E+ EA   L+   EI          Y+   +  A  YLN V+ET      +RE+RA  Y+  G+  KAI+D + A KL +D+ +   ++SK+ Y+ G+ + SL EIRECLKLDPDHK+CF HYK +KKL K I + ++   + RY D + K E + K+E   P+Y +   +  C+C+SK  ++  AI VC      EP N + + D AEA+I +E Y+ AI  Y+   +++ N+++ +EG+ +AQKLLK S+KR+YYKIL V R A K+EI+KAYRKLA ++HPD  +  + KK AE+KFIDI+ AK+VLTD EKR ++D GEDPLDPE Q 
Sbjct:   29 ADVDKHLEMGKKLLAAGQLADALSHFHSAIDGDPDNYVAYYRRATVYLAMGKSKAAIPDLSKVIELKPDFTSARVQRGHLLLKQGKLDEAEEDFKKVLKSNPNEQEEKEANAQLLKSSEIQSMRSQGIAAYKEGDYSTAETYLNFVLETCIWDAEIRELRAECYISQGEPGKAISDLKAASKLKSDNTNAFYKVSKIYYQLGDHEMSLSEIRECLKLDPDHKECFSHYKQVKKLNKQIQAAEELIHEGRYEDALPKYEGILKTEPNVPYYSALVQERSCHCYSKSQQSTEAIRVCTEFLQQEPNNVNALKDRAEAYILEEMYEEAIRDYETAQQNNENDKQIREGLDKAQKLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLAQQWHPDNFQDEEEKKKAEKKFIDIASAKEVLTDPEKRSRFDAGEDPLDPESQQ 465

[Close]

BLAST of J domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000019462.1 (dnaJ homolog subfamily C member 3 like [Source:NCBI gene;Acc:734020])

HSP 1 Score: 353.599 bits (906), Expect = 1.442e-115
Identity = 205/449 (45.66%), Postives = 287/449 (63.92%), Query Frame = 2

Query:  131 LLFNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSF---AYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRG-DNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
            ++ +L ++  + ++  +++ +L+ G +LLAAGQL +AL+ Y  AV+GDPNNYL YY+RA V+LAMGK +SA+ DLS ++ LKP+F+ AR QR N+ LKQG + EA+ED   +LQ  P + EAQ  L  + E+  ++  A   YE   +  AI  L KV+E +      RE+RA  YL  G+   A+ D +   KL ND+R   L+LSKL Y              CLKLD D KDCF HYK +KKL + ++  ++  +++RY D I K E   K+EP  + +   A + +C+C SK    + AI VC  AH  +PQN  ++ D AEA+I +E Y+ A+  +Q+  E D  N+  KEG++RAQKLLK SKKR+YYKIL V R A K+E++KAYRKLA ++HPD  +  + KK AE+KFIDI+ AK+VLTD E RQK D GEDPLDPE Q 
Sbjct:   20 VILDLQLDGLLAANHAEIEGHLEMGRKLLAAGQLAEALSHYHAAVDGDPNNYLTYYKRAAVYLAMGKFRSALPDLSRAIQLKPDFLAARLQRGNILLKQGDVQEAREDFLSVLQSSPTNEEAQNQLERVKEVESSMGGASEAYERRDYYGAIALLEKVIEFSPWDPSARELRAECYLLVGELSNAVQDLKPTTKLRNDNRAAFLKLSKLYYMRPEGG--------CLKLDQDDKDCFSHYKQVKKLSRQLDMAEEFIQEQRYEDAIEKYEASIKTEPRVEEYSRRAKERICHCLSKSQRTEEAISVCTEAHERDPQNPLILRDRAEAYILNEEYEKAVEDFQQAKELDGENEEMKEGLERAQKLLKQSKKRDYYKILGVKRNANKQEVIKAYRKLAQQWHPDNFQSEEEKKEAEKKFIDIAAAKEVLTDPEMRQKVDAGEDPLDPENQQ 460

[Close]

BLAST of J domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000019451.1 (dnaJ homolog subfamily C member 3 like [Source:NCBI gene;Acc:734020])

HSP 1 Score: 352.058 bits (902), Expect = 5.521e-115
Identity = 204/438 (46.58%), Postives = 281/438 (64.16%), Query Frame = 2

Query:  161 VTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSF---AYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRG-DNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQ 1462
            + ++  +++ +L+ G +LLAAGQL +AL+ Y  AV+GDPNNYL YY+RA V+LAMGK +SA+ DLS ++ LKP+F+ AR QR N+ LKQG + EA+ED   +LQ  P + EAQ  L  + E+  ++  A   YE   +  AI  L KV+E +      RE+RA  YL  G+   A+ D +   KL ND+R   L+LSKL Y              CLKLD D KDCF HYK +KKL + ++  ++  +++RY D I K E   K+EP  + +   A + +C+C SK    + AI VC  AH  +PQN  ++ D AEA+I +E Y+ A+  +Q+  E D  N+  KEG++RAQKLLK SKKR+YYKIL V R A K+E++KAYRKLA ++HPD  +  + KK AE+KFIDI+ AK+VLTD E RQK D GEDPLDPE Q
Sbjct:   25 LAANHAEIEGHLEMGRKLLAAGQLAEALSHYHAAVDGDPNNYLTYYKRAAVYLAMGKFRSALPDLSRAIQLKPDFLAARLQRGNILLKQGDVQEAREDFLSVLQSSPTNEEAQNQLERVKEVESSMGGASEAYERRDYYGAIALLEKVIEFSPWDPSARELRAECYLLVGELSNAVQDLKPTTKLRNDNRAAFLKLSKLYYMRPEGG--------CLKLDQDDKDCFSHYKQVKKLSRQLDMAEEFIQEQRYEDAIEKYEASIKTEPRVEEYSRRAKERICHCLSKSQRTEEAISVCTEAHERDPQNPLILRDRAEAYILNEEYEKAVEDFQQAKELDGENEEMKEGLERAQKLLKQSKKRDYYKILGVKRNANKQEVIKAYRKLAQQWHPDNFQSEEEKKEAEKKFIDIAAAKEVLTDPEMRQKVDAGEDPLDPENQ 454

[Close]

BLAST of J domain-containing protein vs. Ensembl Mouse
Match: Dnajc3 (DnaJ heat shock protein family (Hsp40) member C3 [Source:MGI Symbol;Acc:MGI:107373])

HSP 1 Score: 358.607 bits (919), Expect = 2.649e-117
Identity = 211/471 (44.80%), Postives = 306/471 (64.97%), Query Frame = 2

Query:   83 FVSMSIINKRLTLIS---ILLFNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKP---EDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPF---YQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDR-NRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
             V+   +  RL  +    ++L +L  E +      DV+K+L+ G +LLAAGQL DAL+Q+  AV+GDP+NY+ YYRRATVFLAMGK+K+A+ DL+  + LK +F  AR QR +L LKQGKL EA++D   +L+  P   E+ EA+  LV   E+      A   ++   +  AI +L+K++E       LRE+RA  ++K G+ +KAI+D + A KL +D+ +   ++S L Y+ G+ + SL E+RECLKLD DHK CF HYK +KKL KLI S ++  +D RY D  +K E++ K+EP    Y   + + +C+C SK  +   AI +C      EP N + + D AEA++ +E YD AI  Y+   E + N+Q+ +EG+++AQ+LLK S+KR+YYKIL V R A K+EI+KAYRKLA ++HPD     + KK AE+KFIDI+ AK+VL+D E R+K+D+GEDPLD E Q 
Sbjct:    1 MVAPGSVGSRLGAVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIALKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSEQEEKEAESQLVKADEMQRLRSQALDAFDGADYTAAITFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKSDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSVAEYTVRSKERICHCFSKDEKPVEAIRICSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYEAAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQ 471

[Close]

BLAST of J domain-containing protein vs. Ensembl Mouse
Match: Dnajc7 (DnaJ heat shock protein family (Hsp40) member C7 [Source:MGI Symbol;Acc:MGI:1928373])

HSP 1 Score: 108.612 bits (270), Expect = 1.109e-24
Identity = 105/416 (25.24%), Postives = 195/416 (46.88%), Query Frame = 2

Query:  251 YDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYN---DCITKA-----ENLKKSEPFYQSFAYQYLCN---CHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDN---KKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPE 1456
            Y KA++  PNN   Y  RA   + +G+ + A+ D   S+ L  +F+    +    +L  G    A       L+   ++ +AQ+   N   + E  ++A+  +E   F   +  +++ +E        + ++A      G   +A       +++ + + D +      LY     ++++    + L++ PDH+      +  K L         A K+  Y    +  T+A      N+K +   Y        CN    +SK+ + + AIE C  A   +          A+ ++  E ++ A+  Y+KV +++   +  K+ +K AQ  LK SK+++YYKIL V + A++ EI KAYRK A  +HPDR+ G +   +K  E+KF ++ +A  +L+D +K+ +YD+G+D LD E
Sbjct:   51 YTKAIDMCPNNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAEVDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQFVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACVACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLY--------CNRGTVNSKLRQLEDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQFEEAVRDYEKVYQTEKTKEH-KQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQD-LDEE 456

[Close]

BLAST of J domain-containing protein vs. Ensembl Mouse
Match: Dnajb8 (DnaJ heat shock protein family (Hsp40) member B8 [Source:MGI Symbol;Acc:MGI:1922801])

HSP 1 Score: 72.0182 bits (175), Expect = 1.056e-13
Identity = 34/65 (52.31%), Postives = 50/65 (76.92%), Query Frame = 2

Query: 1235 NYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYD 1429
            NYY++L V  +A+ ++I KAYRKLA  +HPD+N  DNK+ AE+KF  +S+A +VL+D++KR  YD
Sbjct:    3 NYYEVLGVQSSASPEDIKKAYRKLALRWHPDKNP-DNKEEAEKKFKQVSEAYEVLSDSKKRSVYD 66

[Close]

BLAST of J domain-containing protein vs. Ensembl Mouse
Match: Dnajb11 (DnaJ heat shock protein family (Hsp40) member B11 [Source:MGI Symbol;Acc:MGI:1915088])

HSP 1 Score: 71.633 bits (174), Expect = 5.346e-13
Identity = 39/73 (53.42%), Postives = 54/73 (73.97%), Query Frame = 2

Query: 1232 RNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDN-GEDPL 1447
            R++YKIL V R+A+ K+I KAYRKLA + HPDRN  D +  A+ KF D+  A +VL+D+EKR++YD  GE+ L
Sbjct:   24 RDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDDPQ--AQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGL 94

[Close]

Query: 1232 RNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDN-GEDPL 1447
            R++YKIL V R+A+ K+I KAYRKLA + HPDRN  D +  A+ KF D+  A +VL+D+EKR++YD  GE+ L
Sbjct:   24 RDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDDPQ--AQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGL 94

[Close]

BLAST of J domain-containing protein vs. UniProt/SwissProt
Match: sp|Q27968|DNJC3_BOVIN (DnaJ homolog subfamily C member 3 OS=Bos taurus OX=9913 GN=DNAJC3 PE=1 SV=1)

HSP 1 Score: 365.155 bits (936), Expect = 5.236e-119
Identity = 215/471 (45.65%), Postives = 309/471 (65.61%), Query Frame = 2

Query:   83 FVSMSIINKRLTLIS---ILLFNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKP---EDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSFAY---QYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRG-DNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
             V+   +  RL  +    ++L +L  E +      DV+K+L+ G +LLAAGQL DAL+Q+  AV+GDP+NY+ YYRRATVFLAMGK+K+A+ DL+  + LK +F  AR QR +L LKQGKL EA++D   +L+  P   E+ EAQ  LV   E+      A   +E++ F  AI +L+K++E       LRE+RA  ++K G+ +KAI+D + + KL ND+ +   ++S L YE G+ + SL E+RECLKLD DHK CF HYK +KKL KLI S ++  K+ RY D I+K E++ K+EP    +     + +C+C SK  +   AI VC      EP N + + D AEA++ +E YD AI  Y+   E + N+Q+ +EG+++AQ+LLK S++R+YYKIL V R A K+EI+KAYRKLA ++HPD  +  + KK AE+KFIDI+ AK+VL+D E R+K+D+GEDPLD E Q 
Sbjct:    1 MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIELKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLVKSDEMQRLRSQALDAFESSDFTAAITFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKASSKLKNDNTEAFYKISTLYYELGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIKEGRYTDAISKYESVMKTEPGVHEYTIRSKERICHCFSKDEKPVEAIRVCSEVLQVEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQRRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQ 471

[Close]

BLAST of J domain-containing protein vs. UniProt/SwissProt
Match: sp|Q13217|DNJC3_HUMAN (DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1)

HSP 1 Score: 361.303 bits (926), Expect = 1.492e-117
Identity = 213/471 (45.22%), Postives = 306/471 (64.97%), Query Frame = 2

Query:   83 FVSMSIINKRLTLIS---ILLFNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKP---EDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPF---YQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDR-NRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
             V+   +  RL  +    ++L +L  E +      DV+K+L+ G +LLAAGQL DAL+Q+  AV+GDP+NY+ YYRRATVFLAMGK+K+A+ DL+  + LK +F  AR QR +L LKQGKL EA++D   +L+  P   E+ EAQ  L+   E+      A   + +  +  AI +L+K++E       LRE+RA  ++K G+ +KAI+D + A KL ND+ +   ++S L Y+ G+ + SL E+RECLKLD DHK CF HYK +KKL KLI S ++  +D RY D  +K E++ K+EP    Y   + + +C+C SK  +   AI VC      EP N + + D AEA++ +E YD AI  Y+   E + N+Q+ +EG+++AQ+LLK S+KR+YYKIL V R A K+EI+KAYRKLA ++HPD     + KK AE+KFIDI+ AK+VL+D E R+K+D+GEDPLD E Q 
Sbjct:    1 MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQ 471

[Close]

BLAST of J domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9R0T3|DNJC3_RAT (DnaJ homolog subfamily C member 3 OS=Rattus norvegicus OX=10116 GN=Dnajc3 PE=1 SV=3)

HSP 1 Score: 358.607 bits (919), Expect = 1.700e-116
Identity = 211/471 (44.80%), Postives = 310/471 (65.82%), Query Frame = 2

Query:   83 FVSMSIINKRLTLIS---ILLFNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKP---EDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPF---YQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRG-DNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
             V+   +  RL  +    ++L +L  E +      DV+K+L+ G +LLAAGQL DAL+Q+  AV+GDP+NY+ YYRRATVFLAMGK+K+A+ DL+  + LK +F  AR QR +L LKQG+L+EA++D   +L+  P   E+ EAQ  LV   E+      A   +++  +  AI +L++++E       LRE+RA  ++K G+ +KAI+D + A KL ND+ +   ++S L Y+ G+ + SL E+RECLKLD DHK CF HYK +KKL KLI S ++  +D RY D  +K E++ K+EP    Y   + + +C+C SK  +   AI++C      EP N + + D AEA++ +E YD AI  Y+   E + N+Q+ +EG+++AQ+LLK S+KR+YYKIL V R A K+EI+KAYRKLA ++HPD  +  + KK AE+KFIDI+ AK+VL+D E R+K+D+GEDPLD E Q 
Sbjct:    1 MVAPGSVRSRLGAVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTRVIELKMDFTAARLQRGHLLLKQGRLAEAEDDFKKVLKSNPSENEEKEAQSQLVKADEMQRLRAQALDAFDSADYTAAITFLDEILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISILYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIGSAEELIRDGRYTDATSKYESVMKAEPSVAEYTVRSKERICHCFSKDEKPVEAIKICSEVLQLEPDNVNALKDRAEAYLIEEMYDEAIQDYEAAQEQNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQSEEEKKKAEKKFIDIAAAKEVLSDPEMRRKFDDGEDPLDAETQQ 471

[Close]

BLAST of J domain-containing protein vs. UniProt/SwissProt
Match: sp|Q91YW3|DNJC3_MOUSE (DnaJ homolog subfamily C member 3 OS=Mus musculus OX=10090 GN=Dnajc3 PE=1 SV=1)

HSP 1 Score: 358.607 bits (919), Expect = 1.853e-116
Identity = 211/471 (44.80%), Postives = 306/471 (64.97%), Query Frame = 2

Query:   83 FVSMSIINKRLTLIS---ILLFNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKP---EDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPF---YQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDR-NRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
             V+   +  RL  +    ++L +L  E +      DV+K+L+ G +LLAAGQL DAL+Q+  AV+GDP+NY+ YYRRATVFLAMGK+K+A+ DL+  + LK +F  AR QR +L LKQGKL EA++D   +L+  P   E+ EA+  LV   E+      A   ++   +  AI +L+K++E       LRE+RA  ++K G+ +KAI+D + A KL +D+ +   ++S L Y+ G+ + SL E+RECLKLD DHK CF HYK +KKL KLI S ++  +D RY D  +K E++ K+EP    Y   + + +C+C SK  +   AI +C      EP N + + D AEA++ +E YD AI  Y+   E + N+Q+ +EG+++AQ+LLK S+KR+YYKIL V R A K+EI+KAYRKLA ++HPD     + KK AE+KFIDI+ AK+VL+D E R+K+D+GEDPLD E Q 
Sbjct:    1 MVAPGSVGSRLGAVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIALKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSEQEEKEAESQLVKADEMQRLRSQALDAFDGADYTAAITFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKSDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSVAEYTVRSKERICHCFSKDEKPVEAIRICSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYEAAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQ 471

[Close]

BLAST of J domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5ZI13|DNJC3_CHICK (DnaJ homolog subfamily C member 3 OS=Gallus gallus OX=9031 GN=DNAJC3 PE=2 SV=1)

HSP 1 Score: 336.65 bits (862), Expect = 5.888e-108
Identity = 199/437 (45.54%), Postives = 288/437 (65.90%), Query Frame = 2

Query:  176 GDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKP---EDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSE---PFYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRG-DNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
             +V+K L+ G +LLAAGQL DAL+ +  A+EGD +NY+ YYRRATV+LAMGK+K+AI DLS  + LK +F  +R QR +L LKQGK  EA++D   +L+  P   E+ EAQ  L    E+      A + Y    +E AI  L++++        LRE+RA  Y+K G+  KAI+D + A KL +D+ +   ++S++ Y+ G+ + SL E+RECLKLD DHK CF  YK +KKL K I S ++  ++ RY D I+K +++ K+E   P Y + A + +C+C SK  +A  AI VC      EP N + + D AEA++ ++ Y+ AI  Y+    +  N+Q+ +EG++RAQ++LK S+KR+YYKIL V R A K+EI+KAYRKLA+++HPD  +  + KK AE+KFIDI+ AK+VLTD E R+K+D GEDPLD E Q 
Sbjct:   35 AEVEKQLEMGKKLLAAGQLADALSHFHAAIEGDSDNYIAYYRRATVYLAMGKSKAAIRDLSKVVELKQDFT-SRLQRGHLLLKQGKFDEAEDDFKNVLKSNPSNNEEKEAQTQLTKSDELQRLYSQALSAYRQEDYEAAIPLLDEILAVCVWDAELRELRAECYIKEGEPSKAISDLKAAAKLKSDNTEAFYKISRIYYQLGDHELSLSEVRECLKLDQDHKQCFSLYKQVKKLNKQIESAEEFIREGRYEDAISKYDSVMKTEPDVPVYATRAKERICHCLSKNQQATEAITVCTQVLQLEPTNVNALKDRAEAYLLEDLYEEAIKDYETAQANSENDQQIREGLERAQRMLKQSQKRDYYKILGVKRNARKQEIIKAYRKLASQWHPDNFQSEEEKKKAEKKFIDIAAAKEVLTDPEMRRKFDAGEDPLDAESQQ 470

[Close]

BLAST of J domain-containing protein vs. TrEMBL
Match: A0A1I8GA67 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 407.527 bits (1046), Expect = 1.780e-132
Identity = 224/469 (47.76%), Postives = 319/469 (68.02%), Query Frame = 2

Query:   83 FVSMSIINKRLTLISILLFNLYIEESV-TSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSFAY------QYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQHQ 1468
            F+S +    R   I I LF+++I +SV  S   ++DK+L+ G +LLAAGQL DAL+ Y  A+E DP NY  Y+RRATV++A+GK+K A+ DL   + LKP+F  A  QR  +YLK G+LS+AK D+  +L+  P + EA K +  +  +AE  E A+   EN ++ DAI +L + +E + +   LR +RA++Y   G+  KA +D R   +L+ D+  G LR+S L Y  G+ +QSL E+RECLKLDPDHKDCFKHYK +KK+ K  +++  ++++K+++ C+   E L K+    Q  A        Y C C +K  ++  A++VC      EP N D +C+ AEA+   + ++ AI+ YQKVLE+D NNQRAKEG+  AQK LK+S++RNYY+IL V R+A K+EILKAYRKLAA+YHPD  +G++K +A+RKFIDISDAK+VLTD EKR K+DNG+DPLDPEQQH+
Sbjct:    3 FLSRTTRIYREIYIIIALFDIWISDSVLASSQAEIDKHLELGKKLLAAGQLADALSHYHAAIELDPTNYQSYFRRATVYMAIGKSKPALPDLDKVIELKPDFATAYLQRGGIYLKTGQLSDAKADLRRVLELDPSNAEAAKQIEQLTPLAEFAENARNLAENGQYTDAIDFLTRALEISPMDADLRALRADAYEAIGEGFKAASDLRAINRLTTDNTAGHLRVSHLFYRLGDPEQSLNEVRECLKLDPDHKDCFKHYKQVKKVAKAFDAVVKSSEEKQWDVCLQSLEKLTKT--IKQKSAGLTRQMDSYQCMCGAKNGDS-AAVDVCSRVLEAEPGNADALCNRAEAYKHQDMFNEAIADYQKVLETDKNNQRAKEGIADAQKKLKSSRRRNYYQILGVPRSARKREILKAYRKLAAQYHPDHYKGNDKASAQRKFIDISDAKEVLTDEEKRAKFDNGQDPLDPEQQHE 468

[Close]

BLAST of J domain-containing protein vs. TrEMBL
Match: K1PZ23 (DnaJ-like protein subfamily C member 3 OS=Crassostrea gigas OX=29159 GN=CGI_10007563 PE=4 SV=1)

HSP 1 Score: 402.519 bits (1033), Expect = 6.125e-132
Identity = 205/409 (50.12%), Postives = 279/409 (68.22%), Query Frame = 2

Query:  251 YDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEP---FYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQHQ 1468
            Y  AV+GDPNNYL Y+RRATVFLAMGK+KSA+ DL+  + LKP+F  AR QRAN+ LKQGKL +A++D   +++  P D EA   L  I E+   I  A  Y+E+ +   A+  L +V+E       L E RA  Y++ G+  KAI+D R    L +D+R    ++S L Y+ G A++SL++IRECLKLDPD K C  HYK +KKLVK IN+ Q+A  + +Y++C+ KA+   K+EP   FYQ     YLC+C++K    + A+ +C       P+N + + D AEA++A E ++ AI+ +QK L  +  N+RA+EG+ +AQKLLK S+K++YYKIL V RTA KKEILKAYRKLAA +HPD+  GD+K  AE+ FIDI+ AK+VLTD EKRQK+DNGEDPLDPEQQ  
Sbjct:   18 YHSAVDGDPNNYLTYFRRATVFLAMGKSKSALPDLTKVIELKPDFTAARIQRANVLLKQGKLDDAEKDFKSVIERGPND-EALSQLNAIAELRRDISEAYMYFEHGQLPTAVDILGRVIEKCPWDPSLHETRAECYIQMGEYYKAISDIRPTTSLRSDNRPAFYKMSDLYYKLGEAEESLIQIRECLKLDPDDKQCQPHYKKVKKLVKQINAAQEAKVNGQYDECLNKAKQFMKTEPNEEFYQLKGQGYLCHCNAKGGHIQEALRICNRLLNKNPENVEALMDRAEAYLASEKWEEAINDFQKALNMEEGNRRAQEGLNKAQKLLKQSQKKDYYKILGVKRTARKKEILKAYRKLAAIWHPDKYDGDDKAKAEKMFIDIAAAKEVLTDPEKRQKFDNGEDPLDPEQQQH 425

[Close]

BLAST of J domain-containing protein vs. TrEMBL
Match: A0A267E2W3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000801g2 PE=4 SV=1)

HSP 1 Score: 398.282 bits (1022), Expect = 1.216e-129
Identity = 220/465 (47.31%), Postives = 315/465 (67.74%), Query Frame = 2

Query:   83 FVSMSIINKRLTLISILLFNLYIEESV-TSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSFAY------QYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPE 1456
            F+S +    R   I I LF+++I +SV  S   ++DK+L+ G +LLAAGQL DAL+ Y  A+E DP NY  Y+RRATV++A+GK+K A+ DL   + LKP+F  A  QR  +YLK G+LS+AK D+  +L+  P + EA K +  +  +AE  E A+   EN ++ DAI +L + +E + +   LR +RA++Y   G+  KA +D R   +L+ D+  G LR+S L Y  G+ +QSL E+RECLKLDPDHKDCFKHYK +KK+ K  +++  ++++K+++ C+   E L K+    Q  A        Y C C +K  ++  A++VC      EP N D +C+ AEA+   + ++ AI+ YQKVLE+D NNQRAKEG+  AQK LK+S++RNYY+IL V R+A K+EILKAYRKLAA+YHPD  +G++K +A+RKFIDISDAK+VLTD EKR++YD+G DPLDPE
Sbjct:    3 FLSRTTRIYREIYIIIALFDIWISDSVLASSQAEIDKHLELGKKLLAAGQLADALSHYHAAIELDPTNYQSYFRRATVYMAIGKSKPALPDLDKVIELKPDFATAYLQRGGIYLKTGQLSDAKADLRRVLELDPSNAEAAKQIEQLTPLAEFAENARNLAENGQYTDAIDFLTRALEISPMDADLRALRADAYEAIGEGFKAASDLRAINRLTTDNTAGHLRVSHLFYRLGDPEQSLNEVRECLKLDPDHKDCFKHYKQVKKVAKAFDAVVKSSEEKQWDVCLQSLEKLTKT--IKQKSAGLTRQMDSYQCMCGAKNGDS-AAVDVCSRVLEAEPGNADALCNRAEAYKHQDMFNEAIADYQKVLETDKNNQRAKEGIADAQKKLKSSRRRNYYQILGVPRSARKREILKAYRKLAAQYHPDHYKGNDKASAQRKFIDISDAKEVLTDEEKRKQYDSGHDPLDPE 464

[Close]

BLAST of J domain-containing protein vs. TrEMBL
Match: A0A1W7RHU9 (DnaJ subfamily C member 3-like protein OS=Agkistrodon contortrix contortrix OX=8713 PE=4 SV=1)

HSP 1 Score: 397.127 bits (1019), Expect = 7.272e-129
Identity = 221/460 (48.04%), Postives = 302/460 (65.65%), Query Frame = 2

Query:  107 KRLTLISILL---FNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEP---FYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRG-DNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
            KRL   + LL   F+L +   + +   ++D +L+ G +LLAAGQL +AL+ Y  AVE DP NYL YY+RAT++LAMGK KSA+ DLS ++ LKP+F+ AR QR N+ LKQG   EAK+D   +L+  PED EAQ  L  + E   +++ A+T ++   +  A+ +L++V+E +      +E+R+  YL  GD  KAI D +   KL ND+R   L+LSKL Y  G  ++SL ++RECLKLD D KDCF HYK +KKL K + S ++  K +RY D I K +   K+EP    Y   A   +C+C SK      AI++C  AH  +P+N  V+ D AEAFI +E ++ AI  YQ+  E D  N+  KEG++RAQKLLK SKKRNYYKIL + R A K+EI+KAYRKLA ++HPD  +  D KK AE++FIDI+ AK+VLTD E RQK+D+GEDPLDPE Q 
Sbjct:   31 KRLLWAASLLCVLFDLQLPGLLAAGQAEIDNHLEMGRKLLAAGQLAEALSHYHSAVEIDPKNYLTYYKRATIYLAMGKFKSALPDLSKAIELKPDFLAARLQRGNILLKQGHTQEAKQDFEAVLKSNPEDAEAQSQLSRVVEQEFSMQEAQTAFQKKNYLGAVSFLDRVIEISPWDPEPKELRSECYLHLGDYNKAIMDLKPTTKLRNDNRAAFLKLSKLYYNLGEHEESLTQVRECLKLDQDDKDCFSHYKQVKKLTKQLESAEEHIKAQRYADAIEKYKAAMKTEPNVEIYTIKAKGRICHCLSKSKRVAEAIDLCSEAHQLDPRNTFVLRDRAEAFILNEEFEKAIEDYQEAKEFDAENEELKEGLERAQKLLKQSKKRNYYKILGIQRNANKQEIIKAYRKLAQQWHPDNFQSEDEKKEAEKRFIDIAAAKEVLTDPEMRQKFDSGEDPLDPENQQ 490

[Close]

BLAST of J domain-containing protein vs. TrEMBL
Match: A0A0F7Z8P5 (DnaJ subfamily C member 3-like protein OS=Crotalus adamanteus OX=8729 PE=2 SV=1)

HSP 1 Score: 394.43 bits (1012), Expect = 1.004e-127
Identity = 214/433 (49.42%), Postives = 291/433 (67.21%), Query Frame = 2

Query:  176 GDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEP---FYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRG-DNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQ 1462
             ++D +L+ G +LLAAGQL +AL+ Y  AVE DP NYL YY+RAT++LAMGK KSA+ DLS ++ LKP+F+ AR QR N+ LKQG   EAK+D   +L+  PED EAQ  L  + E   +++ A+T ++   +  A+ +L++V+E +      +E+R+  YL  GD  KAI D +   KL ND+R   L+LSKL Y  G  ++SL ++RECLKLD D KDCF HYK +KKL K + S ++  K +RY D I K +   K+EP    Y   A  ++C+C SK      AI++C  AH  +P+N  V+ D AEAFI +E ++ AI  YQ+  E D  N+  KEG++RAQKLLK SKKRNYYKIL + R A K+EI+KAYRKLA ++HPD  +  D KK AE++FIDI+ AK+VLTD E RQK+D+GEDPLDPE Q
Sbjct:   57 AEIDNHLEMGRKLLAAGQLAEALSHYHSAVETDPKNYLTYYKRATIYLAMGKFKSALPDLSKAIELKPDFLAARLQRGNILLKQGHTQEAKQDFEAVLKSNPEDAEAQSQLSRVVEQEFSMQEAQTAFQKKNYLGAVSFLDRVIEISPWDPEPKELRSECYLHLGDYNKAIMDLKPTTKLRNDNRAAFLKLSKLYYNLGEHEESLSQVRECLKLDQDDKDCFSHYKQVKKLTKQLESAEEHIKAQRYADAIEKYKAAMKTEPNVEIYTIKAKGWICHCLSKSKRVAEAIDLCSEAHQLDPRNTFVLRDRAEAFILNEEFEKAIEDYQEAKEFDAENEELKEGLERAQKLLKQSKKRNYYKILGIQRNANKQEIIKAYRKLAQQWHPDNFQSEDEKKEAEKRFIDIAAAKEVLTDPEMRQKFDSGEDPLDPENQ 489

[Close]

BLAST of J domain-containing protein vs. Ensembl Cavefish
Match: dnajc3b (dnaJ homolog subfamily C member 3-like [Source:NCBI gene;Acc:103042161])

HSP 1 Score: 381.333 bits (978), Expect = 2.041e-126
Identity = 210/449 (46.77%), Postives = 300/449 (66.82%), Query Frame = 2

Query:  131 LLFNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEP---FYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDN-KKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
            ++ +L ++  + + P +++++L+ G +LLAAGQL +AL+ Y  AVEGD  NYL YY+RA VFLAMGK+KSA+ DL+ ++ LKP+F+ AR QR N+ LKQG   EA+ED   +LQ  P+  EA+  L    E+ E  E A   +    +   I  L+ V+E +      REMRA  Y++ G+ +KAI D   A +L  D+R   L+LS+LLY+ G    SL EIRECLKLD D K+CF HYK +KKL K ++S ++   ++RY + I K E++ K+EP   FY + A + +C    K+ EA+ A++ C  AH  +PQN  ++ D AEA+I  ++Y+ A+  YQ+  E D  NQ  +EG+ RAQKLLK S+KR+YYKIL V R+A K+EI+KAYRKLA ++HPD  + ++ KK AE++FIDI+ AK+VLTD E RQK+D+GEDPLDPE Q 
Sbjct:   22 VVLDLQLDGVLGASPVEIEQHLEMGRKLLAAGQLAEALSHYHSAVEGDSKNYLTYYKRAAVFLAMGKSKSALPDLTRAIQLKPDFLAARIQRGNILLKQGNTQEAREDFEAVLQRSPDQEEARNQLHKAEELEELQEEAHKAHHRGDYTSTIQVLDHVIELSPWDPESREMRAECYIRLGEPRKAILDLTPAARLRTDNRAAFLKLSRLLYDLGEHRDSLSEIRECLKLDQDDKECFAHYKQVKKLSKQMDSAEELISEQRYQEAIDKYESVMKTEPKITFYTTKAKERICFSLVKIKEAEKALDTCSEAHQRDPQNIHILRDRAEAYILLQDYEKAVEDYQEAREFDQENQEIREGLDRAQKLLKLSRKRDYYKILGVSRSANKQEIIKAYRKLAQQWHPDNFQSESEKKEAEKRFIDIASAKEVLTDPEMRQKFDSGEDPLDPENQQ 470

[Close]

Query:  131 LLFNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEP---FYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDN-KKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
            ++ +L ++  + + P +++++L+ G +LLAAGQL +AL+ Y  AVEGD  NYL YY+RA VFLAMGK+KSA+ DL+ ++ LKP+F+ AR QR N+ LKQG   EA+ED   +LQ  P+  EA+  L    E+ E  E A   +    +   I  L+ V+E +      REMRA  Y++ G+ +KAI D   A +L  D+R   L+LS+LLY+ G    SL EIRECLKLD D K+CF HYK +KKL K ++S ++   ++RY + I K E++ K+EP   FY + A + +C    K+ EA+ A++ C  AH  +PQN  ++ D AEA+I  ++Y+ A+  YQ+  E D  NQ  +EG+ RAQKLLK S+KR+YYKIL V R+A K+EI+KAYRKLA ++HPD  + ++ KK AE++FIDI+ AK+VLTD E RQK+D+GEDPLDPE Q 
Sbjct:   22 VVLDLQLDGVLGASPVEIEQHLEMGRKLLAAGQLAEALSHYHSAVEGDSKNYLTYYKRAAVFLAMGKSKSALPDLTRAIQLKPDFLAARIQRGNILLKQGNTQEAREDFEAVLQRSPDQEEARNQLHKAEELEELQEEAHKAHHRGDYTSTIQVLDHVIELSPWDPESREMRAECYIRLGEPRKAILDLTPAARLRTDNRAAFLKLSRLLYDLGEHRDSLSEIRECLKLDQDDKECFAHYKQVKKLSKQMDSAEELISEQRYQEAIDKYESVMKTEPKITFYTTKAKERICFSLVKIKEAEKALDTCSEAHQRDPQNIHILRDRAEAYILLQDYEKAVEDYQEAREFDQENQEIREGLDRAQKLLKLSRKRDYYKILGVSRSANKQEIIKAYRKLAQQWHPDNFQSESEKKEAEKRFIDIASAKEVLTDPEMRQKFDSGEDPLDPENQQ 470

[Close]

BLAST of J domain-containing protein vs. Ensembl Cavefish
Match: dnajc3a (DnaJ heat shock protein family (Hsp40) member C3 [Source:NCBI gene;Acc:103030310])

HSP 1 Score: 380.178 bits (975), Expect = 7.800e-126
Identity = 212/453 (46.80%), Postives = 295/453 (65.12%), Query Frame = 2

Query:  128 ILLFNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKP---EDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSE---PFYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNR-GDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQH 1465
            ++L +L +E  +      V+++L+ G +LLAAGQL DAL+ +  AV+GDP NY+ YYRRATV+LAMGK+KSA+ DLS  + LKP+F  AR QR NL LKQGKL +A+ D   +L+  P   E+ EAQ  L    EI   +  A+  +  N +  A  +L+ ++ET       REMRA  ++K G+  KAI+D + A KL ND+     +LS + Y  G+ + SL E+RECLKLDPDH  CF HYK +KKL KLI S ++  + +RY + ++K E++ KS+   P Y   A + +C+C SK  +   AI VC     ++P+N + + D AEA++ DE Y+ AI  ++       N+Q  KEG+ RAQ+LLK S+KR+YYKIL V RTA KKEI+KAYRKLA ++HPD  +  ++KK AE+KFIDI+ AK+VLTD E R K+D GEDPLDPE Q 
Sbjct:   19 LVLLDLQLEGVICGKSNSVEQHLEMGKKLLAAGQLADALSHFHTAVDGDPKNYMAYYRRATVYLAMGKSKSALPDLSKVIELKPDFTSARLQRGNLLLKQGKLDDAESDFKKVLKSSPSSREEQEAQNQLKKSDEIQRLVTQARNDFSRNDYGPAASHLDIIIETCAWDVDSREMRAECFIKLGEMGKAISDLKAASKLRNDNTQAFYKLSTIYYNLGDHEMSLNEVRECLKLDPDHPQCFSHYKRVKKLNKLILSAEELIQQQRYGEAVSKYESVMKSDPNVPQYALLAKERICHCLSKDQQGAQAIPVCSEVLKSDPENVNALKDRAEAYLQDEQYEEAIKDFESAKMHSENDQEIKEGLDRAQRLLKQSQKRDYYKILGVKRTAQKKEIIKAYRKLAQQWHPDNFQDPEDKKKAEKKFIDIAQAKEVLTDPEMRSKFDQGEDPLDPESQQ 471

[Close]

BLAST of J domain-containing protein vs. Ensembl Cavefish
Match: dnajc7 (DnaJ heat shock protein family (Hsp40) member C7 [Source:NCBI gene;Acc:103043863])

HSP 1 Score: 114.005 bits (284), Expect = 2.050e-26
Identity = 105/411 (25.55%), Postives = 193/411 (46.96%), Query Frame = 2

Query:  251 YDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKR-------YNDCIT-KAENLKKSEPFYQSFAYQYLCN---CHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDN---KKAAERKFIDISDAKDVLTDAEKRQKYDNGED 1441
            Y KA++  P N   Y  RA   + + + + A+ED   ++ L   F+    +    +L  G    A      +L+ +P++ +AQ+ L N   I E   MA+  ++   F   +  +++ +E+ +     + ++A      G   +A +     +++   + D +      LY     D+++    + L++ PDH+      +  K L         A K+         Y++ +T    N+K +   Y        CN     SK+ + + AIE C  A   +          A+ ++  E Y+ A+  Y+KV +++   +  K  +K AQ  LK SK+++YYK+L V ++AT+ EI KAYRK A  +HPDR+ G +   +K  E+KF ++ +A  VL+D +K+ +YD+G D
Sbjct:   64 YTKAIDVCPKNASYYGNRAATLMMLSRYREALEDSQQAVRLDDTFVRGHLREGKCHLSLGNAMAASRCFQKVLELEPDNSQAQQELKNAESILEYERMAEIGFDKRDFRMVVFCMDRALESASACHRFKVLKAECLALLGRYPEAQSVASDILRMDATNGDALYVRGLCLYYEDCIDKAVQFFIQALRMAPDHEKARLACRNAKALKAKKEEGNRAFKEGNFEEAYDLYSEALTIDPNNIKTNAKLY--------CNRATVGSKLKKLEQAIEDCTKAIKLDESYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEH-KHLLKTAQLELKKSKRKDYYKVLGVDKSATEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTVLSDPKKKSRYDSGHD 465

[Close]

BLAST of J domain-containing protein vs. Ensembl Cavefish
Match: dnajc7 (DnaJ heat shock protein family (Hsp40) member C7 [Source:NCBI gene;Acc:103043863])

HSP 1 Score: 113.62 bits (283), Expect = 2.101e-26
Identity = 105/411 (25.55%), Postives = 194/411 (47.20%), Query Frame = 2

Query:  251 YDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKR-------YNDCIT-KAENLKKSEPFYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDN---KKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLD 1450
            Y KA++  P N   Y  RA   + + + + A+ED   ++ L   F+    +    +L  G    A      +L+ +P++ +AQ+ L N   I E   MA+  ++   F   +  +++ +E+ +     + ++A      G   +A +     +++   + D +      LY     D+++    + L++ PDH+      +  K L         A K+         Y++ +T    N+K +   Y + A        SK+ + + AIE C  A   +          A+ ++  E Y+ A+  Y+KV +++   +  K  +K AQ  LK SK+++YYK+L V ++AT+ EI KAYRK A  +HPDR+ G +   +K  E+KF ++ +A  VL+D +K+ +YD+G D  D
Sbjct:   64 YTKAIDVCPKNASYYGNRAATLMMLSRYREALEDSQQAVRLDDTFVRGHLREGKCHLSLGNAMAASRCFQKVLELEPDNSQAQQELKNAESILEYERMAEIGFDKRDFRMVVFCMDRALESASACHRFKVLKAECLALLGRYPEAQSVASDILRMDATNGDALYVRGLCLYYEDCIDKAVQFFIQALRMAPDHEKARLACRNAKALKAKKEEGNRAFKEGNFEEAYDLYSEALTIDPNNIKTNAKLYCNRA-----TVGSKLKKLEQAIEDCTKAIKLDESYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEH-KHLLKTAQLELKKSKRKDYYKVLGVDKSATEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTVLSDPKKKSRYDSGHDLED 468

[Close]

BLAST of J domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000796.1 (pep scaffold:Pmarinus_7.0:GL487111:2166:5165:-1 gene:ENSPMAG00000000730.1 transcript:ENSPMAT00000000796.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 61.6178 bits (148), Expect = 8.054e-12
Identity = 30/63 (47.62%), Postives = 45/63 (71.43%), Query Frame = 2

Query: 1241 YKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYD 1429
            Y +L V R+A + +I KAY+ LA E+HPD+NR  N   AE +F++I+ A +VL++ EKR +YD
Sbjct:   39 YAVLGVARSAPQSDIKKAYKALAREWHPDKNRDPN---AEDRFVEITKAYEVLSNEEKRSQYD 98

[Close]

BLAST of J domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001704.1 (pep scaffold:Pmarinus_7.0:GL487204:33:3976:-1 gene:ENSPMAG00000001540.1 transcript:ENSPMAT00000001704.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 62.003 bits (149), Expect = 1.015e-11
Identity = 32/66 (48.48%), Postives = 45/66 (68.18%), Query Frame = 2

Query: 1232 RNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYD 1429
            R YY++L V R A+ +E+ KAYR+LA ++HPD+N  DN + A   F  I  A DVL+DA++R  YD
Sbjct:    2 RCYYEVLGVARNASDEELKKAYRRLALQWHPDKN-ADNVEEATETFKLIQAAYDVLSDAQERAWYD 66

[Close]

BLAST of J domain-containing protein vs. Ensembl Sea Lamprey
Match: ogt.1 (O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-030131-9631])

HSP 1 Score: 63.5438 bits (153), Expect = 9.764e-11
Identity = 62/255 (24.31%), Postives = 114/255 (44.71%), Query Frame = 2

Query:  146 YIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNI----GEIAEAIE------------------MAKTYYENNRFEDA-IGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCF 841
            + E++V+ DP  +D Y+  G  L  A     A+A Y +A+  + N+ +++   A V+   G    AI+    ++ L+PNF  A    AN   ++G ++EA+E  N  L   P   ++   L NI    G I EA+                   +A    +  + +DA + Y   +  + T ++    M  N+  +  D Q A+  +  A++++    D    L+ +  ++GN  +++   R  LKL PD  D +
Sbjct:  214 HFEKAVSLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLNHNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPNFPDAYCNLANALKEKGNIAEAEECYNTALHLCPNHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQDALLHYKEAIRISPTFADAYSNM-GNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAISSYRTALKLKPDFPDAY 467

[Close]

BLAST of J domain-containing protein vs. Ensembl Sea Lamprey
Match: dnaja1 (DnaJ heat shock protein family (Hsp40) member A1 [Source:ZFIN;Acc:ZDB-GENE-030131-2642])

HSP 1 Score: 60.4622 bits (145), Expect = 3.948e-10
Identity = 33/72 (45.83%), Postives = 46/72 (63.89%), Query Frame = 2

Query: 1226 KKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGED 1441
            K+  YY +L V   +T  E+ KAYRKLA +YHPD+N  + +     KF  IS A +VL+DA+KR+ YD G +
Sbjct:    3 KETAYYDLLGVKPNSTADELKKAYRKLALKYHPDKNPNEGE-----KFKQISQAYEVLSDAKKRELYDRGGE 69

[Close]

BLAST of J domain-containing protein vs. Ensembl Sea Lamprey
Match: dnajc5aa (DnaJ (Hsp40) homolog, subfamily C, member 5aa [Source:ZFIN;Acc:ZDB-GENE-031113-20])

HSP 1 Score: 57.3806 bits (137), Expect = 5.668e-10
Identity = 31/63 (49.21%), Postives = 44/63 (69.84%), Query Frame = 2

Query: 1241 YKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYD 1429
            Y +L + + AT  EI K+YRKLA +YHPD+N  DN +A E KF +I++A  +L+D +KR  YD
Sbjct:   18 YIVLGLQKGATADEIKKSYRKLALKYHPDKNP-DNPEAVE-KFKEINNANGILSDLKKRNIYD 78

[Close]

BLAST of J domain-containing protein vs. Ensembl Yeast
Match: SCJ1 (One of several homologs of bacterial chaperone DnaJ; located in the ER lumen where it cooperates with Kar2p to mediate maturation of proteins [Source:SGD;Acc:S000004827])

HSP 1 Score: 67.3958 bits (163), Expect = 1.675e-12
Identity = 32/66 (48.48%), Postives = 49/66 (74.24%), Query Frame = 2

Query: 1232 RNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYD 1429
            ++YY IL + + AT+KEI  AYR+L+ +YHPD+N G  +  A +KFI++ +A DVL+D EK++ YD
Sbjct:   22 QDYYAILEIDKDATEKEIKSAYRQLSKKYHPDKNAGSEE--AHQKFIEVGEAYDVLSDPEKKKIYD 85

[Close]

BLAST of J domain-containing protein vs. Ensembl Yeast
Match: YDJ1 (Type I HSP40 co-chaperone; involved in regulation of HSP90 and HSP70 functions; acts as an adaptor that helps Rsp5p recognize cytosolic misfolded proteins for ubiquitination after heat shock; critical for determining cell size at Start as a function of growth rate; involved in protein translocation across membranes; member of the DnaJ family; chimeric protein in which human p58IPK J domain replaces yeast Ydj1p J domain can complement yeast ydj1 mutant [Source:SGD;Acc:S000005008])

HSP 1 Score: 61.2326 bits (147), Expect = 1.463e-10
Identity = 39/75 (52.00%), Postives = 50/75 (66.67%), Query Frame = 2

Query: 1226 KKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDN-GEDPL 1447
            K+  +Y IL V  TAT  EI KAYRK A +YHPD+N   +++AAE KF + S A ++L+D EKR  YD  GED L
Sbjct:    3 KETKFYDILGVPVTATDVEIKKAYRKCALKYHPDKN--PSEEAAE-KFKEASAAYEILSDPEKRDIYDQFGEDGL 74

[Close]

BLAST of J domain-containing protein vs. Ensembl Yeast
Match: HLJ1 (Co-chaperone for Hsp40p; anchored in the ER membrane; with its homolog Ydj1p promotes ER-associated protein degradation (ERAD) of integral membrane substrates; similar to E. coli DnaJ [Source:SGD;Acc:S000004771])

HSP 1 Score: 58.151 bits (139), Expect = 4.065e-10
Identity = 38/75 (50.67%), Postives = 47/75 (62.67%), Query Frame = 2

Query: 1229 KRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDN-GEDPLD 1450
            K  +Y+IL V R AT  EI KAYRKLA + HPD+N   + KA E  F  I+ A +VL++ EKR  YD  G DP D
Sbjct:   19 KHEFYEILKVDRKATDSEIKKAYRKLAIKLHPDKN--SHPKAGE-AFKVINRAFEVLSNEEKRSIYDRIGRDPDD 90

[Close]

BLAST of J domain-containing protein vs. Ensembl Yeast
Match: SIS1 (Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; shuttles between cytosol and nucleus; mediates delivery of misfolded proteins into the nucleus for degradation; involved in proteasomal degradation of misfolded cytosolic proteins; protein abundance increases in response to DNA replication stress; polyQ aggregates sequester Sis1p and interfere with clearance of misfolded proteins; similar to bacterial DnaJ proteins and mammalian DnaJB1 [Source:SGD;Acc:S000004952])

HSP 1 Score: 55.0694 bits (131), Expect = 1.214e-8
Identity = 28/68 (41.18%), Postives = 43/68 (63.24%), Query Frame = 2

Query: 1226 KKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYD 1429
            K+   Y +L V  +A ++E+ K YRK A +YHPD+  GD +     KF +IS+A ++L D +KR+ YD
Sbjct:    3 KETKLYDLLGVSPSANEQELKKGYRKAALKYHPDKPTGDTE-----KFKEISEAFEILNDPQKREIYD 65

[Close]

BLAST of J domain-containing protein vs. Ensembl Yeast
Match: XDJ1 (Chaperone with a role in facilitating mitochondrial protein import; ascomycete-specific member of the DnaJ-like family, closely related to Ydj1p; predicted to be C-terminally prenylated; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000004080])

HSP 1 Score: 55.0694 bits (131), Expect = 1.804e-8
Identity = 30/64 (46.88%), Postives = 43/64 (67.19%), Query Frame = 2

Query: 1241 YKILNVHRTATKKEILKAYRKLAAEYHPDRNRG-DNKKAAERKFIDISDAKDVLTDAEKRQKYD 1429
            Y +L V R AT +EI  AYRKLA ++HPD+    D+K+  E KF +I+ A ++L+D EK+  YD
Sbjct:   11 YDVLGVTRDATVQEIKTAYRKLALKHHPDKYVDQDSKEVNEIKFKEITAAYEILSDPEKKSHYD 74

[Close]

BLAST of J domain-containing protein vs. Ensembl Nematostella
Match: EDO32703 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUB0])

HSP 1 Score: 337.035 bits (863), Expect = 2.874e-110
Identity = 181/405 (44.69%), Postives = 258/405 (63.70%), Query Frame = 2

Query:  251 YDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSF---AYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPE 1456
            Y  AV+GDPNN+L  ++RATV +A+G+++SAI DL   L L+P F  AR QR N++LKQG+  EA  D   +L++ PE+ +A + L  I  I   +  AK   E      AI  L   +E       LR MRA+ Y + GD  KAI+D +   KL ND+    LR+SKL YE G  +++L E+RECLKLD DHK C   YK +KKL K +++ QD    ++Y++ I K +   ++E   +     A + LC+CH K+  ++ AI+ C AA + +  + D +CD AEA+I +E Y+ A++ +QK    + +  + +EG+ RAQ+LLK S+KR+YYKIL + R   K+EI KAYRKLA ++HPD  +G++KK AE+ FIDI+ AK+VLTD EKR KYD GEDPLDPE
Sbjct:   18 YHAAVDGDPNNFLPRFQRATVLIALGRSRSAIPDLDKVLELRPEFYQARVQRGNVFLKQGRFDEAHIDYEGVLRYSPENKDALQQLGVIEPIKRTVMEAKYAMERGDCHSAIEQLTHAIEVAPWDPELRMMRADCYERQGDLIKAISDIKPTTKLINDNTQAFLRMSKLHYEIGELEEALREVRECLKLDQDHKQCHPFYKKMKKLNKQLSAAQDLINKEQYHEAIDKLKKALRTESKNKPLVGKARRQLCHCHLKLGFSQEAIKECNAALSIDENDVDALCDRAEAYILEEMYNEAVNDFQKAKSINEHLHKVQEGLDRAQRLLKQSQKRDYYKILGLKRNCNKREITKAYRKLAVKWHPDNYKGEDKKKAEKMFIDIAAAKEVLTDPEKRAKYDAGEDPLDPE 422

[Close]

BLAST of J domain-containing protein vs. Ensembl Nematostella
Match: EDO37560 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFH5])

HSP 1 Score: 76.6406 bits (187), Expect = 4.092e-17
Identity = 36/79 (45.57%), Postives = 63/79 (79.75%), Query Frame = 2

Query: 1214 LKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRG---DNKKAAERKFIDISDAKDVLTDAEKRQKYDNGED 1441
            LK SK+++YYKILN+ +TA++ EI KAY+K A ++HPDR+ G   + KK +E++F ++++A  +L+D +K+++YD+G+D
Sbjct:    1 LKKSKRKDYYKILNISKTASEDEIKKAYKKEALKHHPDRHSGASDEQKKMSEKQFKEVNEAYSILSDPKKKRRYDSGQD 79

[Close]

BLAST of J domain-containing protein vs. Ensembl Nematostella
Match: EDO26658 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TBE9])

HSP 1 Score: 68.5514 bits (166), Expect = 2.522e-14
Identity = 35/95 (36.84%), Postives = 65/95 (68.42%), Query Frame = 2

Query: 1103 FIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRG---DNKKAAERKFIDI 1378
             +  E Y+ A+  Y+ + + D +++  +  +++A+  LK SK+++YYKILN+ +TA++ EI KAY+K A ++HPDR+ G   + KK AE++F ++
Sbjct:    1 MMESEKYEEAVRDYESLCKKDRSSREFRRLLEKAKLELKKSKRKDYYKILNISKTASEDEIKKAYKKEALKHHPDRHSGASDEQKKIAEKQFKEV 95

[Close]

BLAST of J domain-containing protein vs. Ensembl Nematostella
Match: EDO40501 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6W8])

HSP 1 Score: 70.4774 bits (171), Expect = 5.413e-14
Identity = 36/73 (49.32%), Postives = 55/73 (75.34%), Query Frame = 2

Query: 1232 RNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDN-GEDPL 1447
            ++YY+IL V R A+ K+I KA+RK+A +YHPD+N+G   K AE KF ++++A +VL+D  KR++YD  GE+ L
Sbjct:   25 KDYYQILGVPRNASDKQIKKAFRKMAVKYHPDKNKG---KDAEEKFREVAEAYEVLSDENKRRQYDQFGEEGL 94

[Close]

BLAST of J domain-containing protein vs. Ensembl Nematostella
Match: EDO35736 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKN4])

HSP 1 Score: 69.3218 bits (168), Expect = 2.108e-13
Identity = 38/78 (48.72%), Postives = 57/78 (73.08%), Query Frame = 2

Query: 1235 NYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDN-GEDPLDPEQQH 1465
            +YY IL V R+A++++I K+YRKLA ++HPD+N   NK+ AERKF +IS+A +VL+D+++R  YD  G+D L     H
Sbjct:    3 DYYDILEVPRSASEQDIKKSYRKLALKWHPDKNP-QNKEEAERKFKEISEAYEVLSDSKRRDVYDRYGKDGLTGNGGH 79

[Close]

BLAST of J domain-containing protein vs. Ensembl Medaka
Match: dnajc3a (DnaJ heat shock protein family (Hsp40) member C3 [Source:NCBI gene;Acc:101166264])

HSP 1 Score: 379.022 bits (972), Expect = 1.927e-125
Identity = 211/470 (44.89%), Postives = 304/470 (64.68%), Query Frame = 2

Query:   74 NIDFVSMSIINKRLTLISILLFNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKP---EDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSF---AYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNR-GDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQ 1462
            +ID V+  I+     ++  +L ++  E       G VD +++ G +LLAAGQL DAL+ +  AV+GDP NY+ +YRRATVFLAMGK+KSA+ DLS  + LKP+F  AR QR NL LKQGKL EA+ D   +L+  P   E+ EA+  L    EI   +  +++ +    +  AI  L+ ++ET       REMRA  Y++ G+  KA++D + A KL ND+     +LS + Y+ G+ + SL E+RECLKLDPDHK C+ HYK +KKL K I S ++  +++RY D ++K E + K+EP  Q F   A + +C+  +K  +A  AI VC     ++P+N +V+ D AEA++ DE Y+ AI  Y+   +   N+ + KEG++RAQ+LLK S++R+YYKIL V RTA KKEI+KAYRKLA ++HPD  +    KK AE++FIDI+ AK+VLTD E R K+D GEDP+DP+ Q
Sbjct:    3 SIDHVTSKILTYMPYIL--VLIDMRYEGVRCGKDGSVDNHMEMGKKLLAAGQLADALSHFHAAVDGDPKNYMAFYRRATVFLAMGKSKSALPDLSRVIELKPDFTSARLQRGNLLLKQGKLDEAESDFKKVLKSNPSDKEEREAKSQLAKSDEIQRLVAQSRSSFNGKDYMTAITLLDTIIETCVWDASSREMRAECYIQMGEMGKAVSDLKAASKLKNDNTQAFYKLSTIYYDLGDHEMSLNEVRECLKLDPDHKQCYNHYKRVKKLNKQIQSAEELIQEQRYVDAVSKYEAVMKTEPNVQQFTLLAKERICHALAKDQQASRAISVCSEVLQSDPENVNVLKDRAEAYVQDEQYEEAIKDYETAGKHSENDHQIKEGLERAQRLLKQSQRRDYYKILGVKRTAKKKEIIKAYRKLAQQWHPDNFQDPQEKKKAEKRFIDIAQAKEVLTDPEMRNKFDQGEDPMDPDSQ 470

[Close]

BLAST of J domain-containing protein vs. Ensembl Medaka
Match: dnajc3b (dnaJ homolog subfamily C member 3 [Source:NCBI gene;Acc:101168077])

HSP 1 Score: 370.548 bits (950), Expect = 3.925e-122
Identity = 208/452 (46.02%), Postives = 300/452 (66.37%), Query Frame = 2

Query:  113 LTLISILLFNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSE---PFYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRG-DNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPE 1456
            L L+ +LL ++ ++    +   +++++L+ G +LLAAGQL +AL+ Y  AVEGD  NYL YY+RA VFLA+GK+KSA+ DL+ ++ LKP+F+ AR QR N+ LKQG   EA+ D   +L+  P+  EA++ L+   E+    E A   +    +  AI  L + +E +     LRE+RA  Y+++GD QKAI D     KL ND+R   L+LS L Y  G   +SL  +RECLKLD D KDCF HYK +KKL K ++S ++   ++RY D I K E++ K+E   PFY + A + +C C  K++    AI+VC  AH  +P+N  ++ D AEA+I +++Y+ A+  YQ+  E D ++   KEG++RAQKLLK S+KR+YYKIL V R+A K+E++KAYRKLA ++HPD  +    KK AE+KFIDI+ AK+VLTD E RQK+D+GEDPLDPE
Sbjct:   16 LPLLCVLL-DMQLDGVFGATRAEIEQHLEMGRKLLAAGQLAEALSHYHSAVEGDSKNYLTYYKRAAVFLALGKSKSALPDLTRAIELKPDFLAARLQRGNILLKQGNTEEARADFESVLKRSPDQEEARQQLMKASELEGLQEEAYAAHHQGEYSAAIAVLERAIEISPWDPDLRELRAECYVRTGDPQKAIQDLTPTTKLRNDNRAAFLKLSLLHYSLGQHHESLNHVRECLKLDQDDKDCFNHYKQVKKLSKQLDSAEELILEERYRDAIDKYESVMKTESDVPFYTNLAKERICFCFVKLNLVSEAIDVCSEAHQRDPRNAKILRDRAEAYILNQDYEKAVEDYQEAREFDGDSNDIKEGLERAQKLLKVSQKRDYYKILGVSRSANKQEVIKAYRKLAQQWHPDNFQSEAEKKEAEKKFIDIASAKEVLTDPEMRQKFDSGEDPLDPE 466

[Close]

BLAST of J domain-containing protein vs. Ensembl Medaka
Match: dnajc3b (dnaJ homolog subfamily C member 3 [Source:NCBI gene;Acc:101168077])

HSP 1 Score: 366.696 bits (940), Expect = 7.757e-121
Identity = 204/431 (47.33%), Postives = 289/431 (67.05%), Query Frame = 2

Query:  176 GDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSE---PFYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRG-DNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPE 1456
             +++++L+ G +LLAAGQL +AL+ Y  AVEGD  NYL YY+RA VFLA+GK+KSA+ DL+ ++ LKP+F+ AR QR N+ LKQG   EA+ D   +L+  P+  EA++ L+   E+    E A   +    +  AI  L + +E +     LRE+RA  Y+++GD QKAI D     KL ND+R   L+LS L Y  G   +SL  +RECLKLD D KDCF HYK +KKL K ++S ++   ++RY D I K E++ K+E   PFY + A + +C C  K++    AI+VC  AH  +P+N  ++ D AEA+I +++Y+ A+  YQ+  E D ++   KEG++RAQKLLK S+KR+YYKIL V R+A K+E++KAYRKLA ++HPD  +    KK AE+KFIDI+ AK+VLTD E RQK+D+GEDPLDPE
Sbjct:   29 AEIEQHLEMGRKLLAAGQLAEALSHYHSAVEGDSKNYLTYYKRAAVFLALGKSKSALPDLTRAIELKPDFLAARLQRGNILLKQGNTEEARADFESVLKRSPDQEEARQQLMKASELEGLQEEAYAAHHQGEYSAAIAVLERAIEISPWDPDLRELRAECYVRTGDPQKAIQDLTPTTKLRNDNRAAFLKLSLLHYSLGQHHESLNHVRECLKLDQDDKDCFNHYKQVKKLSKQLDSAEELILEERYRDAIDKYESVMKTESDVPFYTNLAKERICFCFVKLNLVSEAIDVCSEAHQRDPRNAKILRDRAEAYILNQDYEKAVEDYQEAREFDGDSNDIKEGLERAQKLLKVSQKRDYYKILGVSRSANKQEVIKAYRKLAQQWHPDNFQSEAEKKEAEKKFIDIASAKEVLTDPEMRQKFDSGEDPLDPE 459

[Close]

BLAST of J domain-containing protein vs. Ensembl Medaka
Match: dnajc3a (DnaJ heat shock protein family (Hsp40) member C3 [Source:NCBI gene;Acc:101166264])

HSP 1 Score: 279.641 bits (714), Expect = 6.504e-87
Identity = 145/331 (43.81%), Postives = 214/331 (64.65%), Query Frame = 2

Query:  482 EDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSF---AYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNR-GDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQ 1462
            E+ EA+  L    EI   +  +++ +    +  AI  L+ ++ET       REMRA  Y++ G+  KA++D + A KL ND+     +LS + Y+ G+ + SL E+RECLKLDPDHK C+ HYK +KKL K I S ++  +++RY D ++K E + K+EP  Q F   A + +C+  +K  +A  AI VC     ++P+N +V+ D AEA++ DE Y+ AI  Y+   +   N+ + KEG++RAQ+LLK S++R+YYKIL V RTA KKEI+KAYRKLA ++HPD  +    KK AE++FIDI+ AK+VLTD E R K+D GEDP+DP+ Q
Sbjct:  150 EEREAKSQLAKSDEIQRLVAQSRSSFNGKDYMTAITLLDTIIETCVWDASSREMRAECYIQMGEMGKAVSDLKAASKLKNDNTQAFYKLSTIYYDLGDHEMSLNEVRECLKLDPDHKQCYNHYKRVKKLNKQIQSAEELIQEQRYVDAVSKYEAVMKTEPNVQQFTLLAKERICHALAKDQQASRAISVCSEVLQSDPENVNVLKDRAEAYVQDEQYEEAIKDYETAGKHSENDHQIKEGLERAQRLLKQSQRRDYYKILGVKRTAKKKEIIKAYRKLAQQWHPDNFQDPQEKKKAEKRFIDIAQAKEVLTDPEMRNKFDQGEDPMDPDSQ 480

[Close]

BLAST of J domain-containing protein vs. Ensembl Medaka
Match: dnajc7 (DnaJ heat shock protein family (Hsp40) member C7 [Source:NCBI gene;Acc:101161810])

HSP 1 Score: 114.775 bits (286), Expect = 7.230e-27
Identity = 107/408 (26.23%), Postives = 193/408 (47.30%), Query Frame = 2

Query:  251 YDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKD-------KRYNDCIT-KAENLKKSEPFYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDN---KKAAERKFIDISDAKDVLTDAEKRQKYDNGED 1441
            Y KA++  P N   Y  RA   + + + + A+ED   ++ L  NF+    +    +L  G    A+     +L+ + E+ +AQ+ + N   I E   MA+  +E   F   +  +++ +E+       + ++A      G   +A +     +++ + + D +      LY     D+++    + L++ PDH       +  K L         A KD       + Y++ +T    N+K +   Y + A        SK+ +   AIE C  A   +          A+ ++  E Y+ A+  Y+KV +++   +  K  +K AQ  LK SK+++YYKIL V + AT+ EI KAYRK A  +HPDR+ G +   +K  E+KF ++ +A  VL+D +K+ +YD+G+D
Sbjct:   51 YTKAIDMCPRNPSYYGNRAATLMMLCRYREALEDAQQAVRLDGNFVKGHLREGKCHLSLGNAMAARRCFQKVLELELENGQAQQEVKNAESILEYERMAEIGFEKRDFRMVVFCMDRALESAPACHKFKILKAECLALLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIDKAVQFFVQALRMAPDHDKARLACRDAKALKAKKEEGNKAFKDGNFEAAYELYSEALTIDPNNIKTNAKLYCNRA-----TVGSKLKKLDQAIEDCTKAIKLDETYIKAYLRRAQCYMDTELYEEAVRDYEKVYQTEKTKEH-KHLLKTAQLELKKSKRKDYYKILGVEKNATEDEIKKAYRKRALLHHPDRHSGASPELQKEEEKKFKEVGEAFSVLSDPKKKSRYDSGQD 452

[Close]

BLAST of J domain-containing protein vs. Planmine SMEST
Match: SMESG000009124.1 (SMESG000009124.1)

HSP 1 Score: 901.738 bits (2329), Expect = 0.000e+0
Identity = 455/459 (99.13%), Postives = 455/459 (99.13%), Query Frame = 2

Query:   92 MSIINKRLTLISILLFNLYIEESVTSDPGDVDKYLQTGTRXXXXXXXXXXXXXYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQHQ 1468
            MSIINKR TLISILLFNLYIEESVTSDPGDVDKYLQTGTRLLAAGQLLDAL QYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCI KAE LKKSEPFYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQHQ
Sbjct:    1 MSIINKRFTLISILLFNLYIEESVTSDPGDVDKYLQTGTRLLAAGQLLDALVQYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIPARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIEMAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAINDFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCFKHYKFIKKLVKLINSIQDAAKDKRYNDCIIKAEKLKKSEPFYQSFAYQYLCNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISYYQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGEDPLDPEQQHQ 459

[Close]

BLAST of J domain-containing protein vs. Planmine SMEST
Match: SMESG000005351.1 (SMESG000005351.1)

HSP 1 Score: 70.0922 bits (170), Expect = 2.399e-13
Identity = 37/64 (57.81%), Postives = 46/64 (71.88%), Query Frame = 2

Query: 1238 YYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYD 1429
            YY ILNV   +   EI K YRKLA  +HPD+N  DNK  AE+KF +IS+A +VL+DAEKR+ YD
Sbjct:    6 YYDILNVSPNSDASEIKKQYRKLALRWHPDKNP-DNKIEAEKKFKEISEAYEVLSDAEKRKMYD 68

[Close]

BLAST of J domain-containing protein vs. Planmine SMEST
Match: SMESG000027166.1 (SMESG000027166.1)

HSP 1 Score: 67.3958 bits (163), Expect = 1.198e-12
Identity = 34/65 (52.31%), Postives = 47/65 (72.31%), Query Frame = 2

Query: 1235 NYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYD 1429
            +YYK+L V + A KK+I  AYRKLA +YHPD+N+   +K A  KF+ I+ A +VL+D  KRQ+YD
Sbjct:   24 DYYKLLGVSKNADKKQIKSAYRKLAVKYHPDKNK---EKDAGEKFMKITKAYEVLSDQNKRQQYD 85

[Close]

BLAST of J domain-containing protein vs. Planmine SMEST
Match: SMESG000017290.1 (SMESG000017290.1)

HSP 1 Score: 66.2402 bits (160), Expect = 2.483e-11
Identity = 35/68 (51.47%), Postives = 48/68 (70.59%), Query Frame = 2

Query: 1229 KRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDN 1432
            K++YYKIL V++ A+ KEI  AY +LA +YHPD N+  N K AE KF D S+A +VL+D  K+ +YD 
Sbjct:   28 KKDYYKILGVNKNASPKEIKSAYYQLAKKYHPDTNK--NNKDAEEKFKDASEAYEVLSDTNKKAEYDT 93

[Close]

BLAST of J domain-containing protein vs. Planmine SMEST
Match: SMESG000012107.1 (SMESG000012107.1)

HSP 1 Score: 65.855 bits (159), Expect = 3.063e-11
Identity = 36/70 (51.43%), Postives = 46/70 (65.71%), Query Frame = 2

Query: 1226 KKRNYYKILNVHRTATKKEILKAYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNG 1435
            K+  YY IL VH   +++E+ KAYRKLA +YHPD+N       A  KF +IS A +VL DA+KRQ YD G
Sbjct:    3 KETKYYDILGVHPNVSEQELKKAYRKLALKYHPDKN-----PDAGDKFKEISQAFEVLADAKKRQIYDEG 67

The following BLAST results are available for this feature:

BLAST of J domain-containing protein vs. Ensembl Human
BLAST of J domain-containing protein vs. Ensembl Celegans
BLAST of J domain-containing protein vs. Ensembl Fly
BLAST of J domain-containing protein vs. Ensembl Zebrafish
BLAST of J domain-containing protein vs. Ensembl Xenopus
BLAST of J domain-containing protein vs. Ensembl Mouse
BLAST of J domain-containing protein vs. UniProt/SwissProt
BLAST of J domain-containing protein vs. TrEMBL
BLAST of J domain-containing protein vs. Ensembl Cavefish
BLAST of J domain-containing protein vs. Ensembl Sea Lamprey
BLAST of J domain-containing protein vs. Ensembl Yeast
BLAST of J domain-containing protein vs. Ensembl Nematostella
BLAST of J domain-containing protein vs. Ensembl Medaka
BLAST of J domain-containing protein vs. Planmine SMEST

BLAST of J domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
DNAJC3	3.106e-118	45.22	DnaJ heat shock protein family (Hsp40) member C3 [...	[more]
DNAJC3	3.747e-103	43.38	DnaJ heat shock protein family (Hsp40) member C3 [...	[more]
DNAJC7	1.071e-24	25.48	DnaJ heat shock protein family (Hsp40) member C7 [...	[more]
DNAJC7	1.456e-23	25.25	DnaJ heat shock protein family (Hsp40) member C7 [...	[more]
DNAJC7	1.456e-23	25.25	DnaJ heat shock protein family (Hsp40) member C7 [...	[more]

BLAST of J domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dnj-7	3.911e-97	40.80	DNaJ domain (Prokaryotic heat shock protein) [Sou...	[more]
dnj-28	5.586e-80	37.99	DNaJ domain (Prokaryotic heat shock protein) [Sou...	[more]
dnj-22	6.876e-13	49.35	DNaJ domain (Prokaryotic heat shock protein) [Sou...	[more]
dnj-20	8.032e-12	52.05	DnaJ homolog dnj-20 [Source:UniProtKB/Swiss-Prot;...	[more]
dnj-13	1.387e-11	47.95	DNaJ domain (Prokaryotic heat shock protein) [Sou...	[more]

BLAST of J domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
P58IPK	2.001e-105	40.55	gene:FBgn0037718 transcript:FBtr0082074	[more]
Tpr2	1.151e-23	23.84	gene:FBgn0032586 transcript:FBtr0080867	[more]
Tpr2	1.151e-23	23.84	gene:FBgn0032586 transcript:FBtr0333488	[more]
Tpr2	1.503e-23	23.84	gene:FBgn0032586 transcript:FBtr0333486	[more]
Tpr2	2.340e-23	23.84	gene:FBgn0032586 transcript:FBtr0080866	[more]

BLAST of J domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dnajc3b	4.440e-122	45.62	DnaJ (Hsp40) homolog, subfamily C, member 3b [Sour...	[more]
dnajc3a	6.529e-118	45.38	DnaJ (Hsp40) homolog, subfamily C, member 3a [Sour...	[more]
dnajc3a	6.529e-118	45.38	DnaJ (Hsp40) homolog, subfamily C, member 3a [Sour...	[more]
dnajc7	3.894e-27	25.79	DnaJ (Hsp40) homolog, subfamily C, member 7 [Sourc...	[more]
dnajc7	4.557e-27	25.79	DnaJ (Hsp40) homolog, subfamily C, member 7 [Sourc...	[more]

BLAST of J domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSXETT00000019480.1	5.701e-123	46.88	dnaJ homolog subfamily C member 3 like [Source:NCB...	[more]
gask1b	1.174e-122	46.50	golgi associated kinase 1B [Source:Xenbase;Acc:XB-...	[more]
gask1b	4.195e-121	47.83	golgi associated kinase 1B [Source:Xenbase;Acc:XB-...	[more]
ENSXETT00000019462.1	1.442e-115	45.66	dnaJ homolog subfamily C member 3 like [Source:NCB...	[more]
ENSXETT00000019451.1	5.521e-115	46.58	dnaJ homolog subfamily C member 3 like [Source:NCB...	[more]

BLAST of J domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Dnajc3	2.649e-117	44.80	DnaJ heat shock protein family (Hsp40) member C3 [...	[more]
Dnajc7	1.109e-24	25.24	DnaJ heat shock protein family (Hsp40) member C7 [...	[more]
Dnajb8	1.056e-13	52.31	DnaJ heat shock protein family (Hsp40) member B8 [...	[more]
Dnajb11	5.346e-13	53.42	DnaJ heat shock protein family (Hsp40) member B11 ...	[more]
Dnajb11	5.346e-13	53.42	DnaJ heat shock protein family (Hsp40) member B11 ...	[more]

BLAST of J domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q27968\|DNJC3_BOVIN	5.236e-119	45.65	DnaJ homolog subfamily C member 3 OS=Bos taurus OX...	[more]
sp\|Q13217\|DNJC3_HUMAN	1.492e-117	45.22	DnaJ homolog subfamily C member 3 OS=Homo sapiens ...	[more]
sp\|Q9R0T3\|DNJC3_RAT	1.700e-116	44.80	DnaJ homolog subfamily C member 3 OS=Rattus norveg...	[more]
sp\|Q91YW3\|DNJC3_MOUSE	1.853e-116	44.80	DnaJ homolog subfamily C member 3 OS=Mus musculus ...	[more]
sp\|Q5ZI13\|DNJC3_CHICK	5.888e-108	45.54	DnaJ homolog subfamily C member 3 OS=Gallus gallus...	[more]

BLAST of J domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1I8GA67	1.780e-132	47.76	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
K1PZ23	6.125e-132	50.12	DnaJ-like protein subfamily C member 3 OS=Crassost...	[more]
A0A267E2W3	1.216e-129	47.31	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A1W7RHU9	7.272e-129	48.04	DnaJ subfamily C member 3-like protein OS=Agkistro...	[more]
A0A0F7Z8P5	1.004e-127	49.42	DnaJ subfamily C member 3-like protein OS=Crotalus...	[more]

BLAST of J domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dnajc3b	2.041e-126	46.77	dnaJ homolog subfamily C member 3-like [Source:NCB...	[more]
dnajc3b	2.041e-126	46.77	dnaJ homolog subfamily C member 3-like [Source:NCB...	[more]
dnajc3a	7.800e-126	46.80	DnaJ heat shock protein family (Hsp40) member C3 [...	[more]
dnajc7	2.050e-26	25.55	DnaJ heat shock protein family (Hsp40) member C7 [...	[more]
dnajc7	2.101e-26	25.55	DnaJ heat shock protein family (Hsp40) member C7 [...	[more]

BLAST of J domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000000796.1	8.054e-12	47.62	pep scaffold:Pmarinus_7.0:GL487111:2166:5165:-1 ge...	[more]
ENSPMAT00000001704.1	1.015e-11	48.48	pep scaffold:Pmarinus_7.0:GL487204:33:3976:-1 gene...	[more]
ogt.1	9.764e-11	24.31	O-linked N-acetylglucosamine (GlcNAc) transferase,...	[more]
dnaja1	3.948e-10	45.83	DnaJ heat shock protein family (Hsp40) member A1 [...	[more]
dnajc5aa	5.668e-10	49.21	DnaJ (Hsp40) homolog, subfamily C, member 5aa [Sou...	[more]

BLAST of J domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
SCJ1	1.675e-12	48.48	One of several homologs of bacterial chaperone Dna...	[more]
YDJ1	1.463e-10	52.00	Type I HSP40 co-chaperone; involved in regulation ...	[more]
HLJ1	4.065e-10	50.67	Co-chaperone for Hsp40p; anchored in the ER membra...	[more]
SIS1	1.214e-8	41.18	Type II HSP40 co-chaperone that interacts with the...	[more]
XDJ1	1.804e-8	46.88	Chaperone with a role in facilitating mitochondria...	[more]

BLAST of J domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO32703	2.874e-110	44.69	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37560	4.092e-17	45.57	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO26658	2.522e-14	36.84	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO40501	5.413e-14	49.32	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35736	2.108e-13	48.72	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of J domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dnajc3a	1.927e-125	44.89	DnaJ heat shock protein family (Hsp40) member C3 [...	[more]
dnajc3b	3.925e-122	46.02	dnaJ homolog subfamily C member 3 [Source:NCBI gen...	[more]
dnajc3b	7.757e-121	47.33	dnaJ homolog subfamily C member 3 [Source:NCBI gen...	[more]
dnajc3a	6.504e-87	43.81	DnaJ heat shock protein family (Hsp40) member C3 [...	[more]
dnajc7	7.230e-27	26.23	DnaJ heat shock protein family (Hsp40) member C7 [...	[more]

BLAST of J domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000009124.1	0.000e+0	99.13	SMESG000009124.1	[more]
SMESG000005351.1	2.399e-13	57.81	SMESG000005351.1	[more]
SMESG000027166.1	1.198e-12	52.31	SMESG000027166.1	[more]
SMESG000017290.1	2.483e-11	51.47	SMESG000017290.1	[more]
SMESG000012107.1	3.063e-11	51.43	SMESG000012107.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30010506 ID=SMED30010506|Name=J domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1752bp
TAAGATTTGAACACACCGAATTAAATTATCAACCTATTAATTTCAAATTA
CACTTATTATACGTATACTTAGGAACATTGATTTTGTTTCAATGTCAATC
ATAAATAAGCGGTTAACTTTGATATCCATTTTACTTTTTAATCTTTATAT
AGAAGAATCTGTTACCTCTGATCCTGGAGACGTGGACAAGTATCTTCAAA
CTGGGACACGGTTACTAGCAGCTGGACAATTATTAGATGCCCTTGCGCAA
TATGATAAGGCAGTCGAAGGAGATCCAAACAATTATTTGATATATTACCG
CAGAGCTACAGTGTTTTTAGCTATGGGAAAAACTAAATCAGCCATTGAAG
ATTTAAGTAATTCGTTATTATTAAAGCCAAATTTTATTCCGGCAAGAACA
CAAAGAGCCAACTTATATTTAAAACAAGGGAAATTATCAGAAGCAAAAGA
AGATATTAATTTACTGCTTCAGCACAAACCAGAGGACGTTGAAGCCCAGA
AAATGCTAGTAAACATCGGTGAAATTGCTGAGGCTATTGAAATGGCCAAG
ACATACTATGAAAATAATCGGTTCGAAGATGCCATTGGATATCTGAACAA
AGTCATGGAAACCACAACTCTCAGTGAATATTTGCGTGAAATGCGAGCAA
ATAGCTACTTGAAGTCCGGTGACAATCAAAAGGCAATAAATGACTTTAGG
TACGCAGTTAAATTGTCCAATGATGACAGAGATGGCATTTTGCGATTGAG
TAAATTGCTGTATGAAACCGGCAACGCAGATCAGTCATTGGTGGAAATTC
GAGAGTGTCTTAAACTCGATCCCGATCATAAAGACTGTTTTAAGCATTAT
AAATTCATTAAAAAACTTGTCAAATTGATCAACTCCATTCAAGACGCAGC
CAAAGACAAGCGATATAACGACTGTATTACTAAAGCTGAAAATTTGAAAA
AATCTGAGCCATTTTATCAATCCTTCGCATATCAATATCTATGCAATTGC
CATAGCAAGGTCAGTGAAGCGAAAACCGCTATTGAAGTGTGTGAAGCTGC
ACATGCGAATGAGCCTCAGAATTGGGATGTAATCTGTGATTTAGCGGAAG
CATTTATAGCCGATGAAAATTACGATTCAGCGATTAGCTACTATCAGAAA
GTTCTTGAATCAGACAATAATAATCAGCGAGCAAAAGAAGGAATGAAAAG
AGCTCAGAAATTGCTGAAAAATTCTAAAAAAAGAAATTATTACAAAATAT
TAAATGTTCACAGAACTGCAACCAAAAAAGAAATTCTCAAAGCATACCGG
AAGCTAGCAGCCGAATATCATCCTGATCGTAATAGAGGTGATAACAAAAA
AGCAGCAGAAAGAAAATTTATCGACATTTCTGACGCAAAAGATGTTTTAA
CCGATGCTGAGAAGCGCCAAAAATATGACAATGGTGAAGATCCATTAGAT
CCAGAACAGCAACATCAAGGTCCAACAGGGAATCCATTTGGTGGATTCAC
ATTCCATAACTTTAATCCCTTTGAAGATGGGGGATTTGAATTTCATTTTG
GCTGATAAATATCAAATAAATACTTTTATTATCTTATTTTTTGTGCCTAA
AATAAAAAATAAAAAATCAGTCGGATCAAATCATATTTCTCTTGTTTTCA
ACTATTTTTTTTGAAAATAAATCAGTTACTGTTTGCTTGATTAATTATAA
ATTTTTCCGATTTCCACACGAAATTGCTTTGAATTTATAAGAATTGTGAA
CT

protein sequence of SMED30010506-orf-1

>SMED30010506-orf-1 ID=SMED30010506-orf-1|Name=SMED30010506-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=488bp
MSIINKRLTLISILLFNLYIEESVTSDPGDVDKYLQTGTRLLAAGQLLDA
LAQYDKAVEGDPNNYLIYYRRATVFLAMGKTKSAIEDLSNSLLLKPNFIP
ARTQRANLYLKQGKLSEAKEDINLLLQHKPEDVEAQKMLVNIGEIAEAIE
MAKTYYENNRFEDAIGYLNKVMETTTLSEYLREMRANSYLKSGDNQKAIN
DFRYAVKLSNDDRDGILRLSKLLYETGNADQSLVEIRECLKLDPDHKDCF
KHYKFIKKLVKLINSIQDAAKDKRYNDCITKAENLKKSEPFYQSFAYQYL
CNCHSKVSEAKTAIEVCEAAHANEPQNWDVICDLAEAFIADENYDSAISY
YQKVLESDNNNQRAKEGMKRAQKLLKNSKKRNYYKILNVHRTATKKEILK
AYRKLAAEYHPDRNRGDNKKAAERKFIDISDAKDVLTDAEKRQKYDNGED
PLDPEQQHQGPTGNPFGGFTFHNFNPFEDGGFEFHFG*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0005783	endoplasmic reticulum
GO:0005829	cytosol

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000136	whole organism
PLANA:0000418	head
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036869	J_dom_sf
IPR015155	PFU
IPR001623	DnaJ_domain
IPR019734	TPR_repeat
IPR011990	TPR-like_helical_dom_sf
IPR013026	TPR-contain_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0004860	protein kinase inhibitor activity
GO:0019901	protein kinase binding

Vocabulary: **biological process**
Term	Definition
GO:0006417	regulation of translation
GO:0006469	negative regulation of protein kinase activity
GO:0006986	response to unfolded protein
GO:0036494	positive regulation of translation initiation in response to endoplasmic reticulum stress
GO:0070417	cellular response to cold
GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 361..381
None	No IPR available	PFAM	PF14559	TPR_19	coord: 76..138 e-value: 3.2E-6 score: 27.5
None	No IPR available	PANTHER	PTHR44140	FAMILY NOT NAMED	coord: 13..486
None	No IPR available	PANTHER	PTHR44140:SF3	DNAJ HOMOLOG SUBFAMILY C MEMBER 3	coord: 13..486
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..26 score: 0.635
IPR001623	DnaJ domain	PRINTS	PR00625	JDOMAIN	coord: 421..441 score: 43.07 coord: 384..402 score: 47.81 coord: 402..417 score: 58.74
IPR001623	DnaJ domain	SMART	SM00271	dnaj_3	coord: 381..441 e-value: 1.9E-23 score: 93.9
IPR001623	DnaJ domain	PFAM	PF00226	DnaJ	coord: 382..446 e-value: 4.8E-22 score: 77.9
IPR001623	DnaJ domain	PROSITE	PS50076	DNAJ_2	coord: 382..449 score: 19.718
IPR001623	DnaJ domain	CDD	cd06257	DnaJ	coord: 382..438 e-value: 1.70708E-18 score: 77.2005
IPR019734	Tetratricopeptide repeat	SMART	SM00028	tpr_5	coord: 65..98 e-value: 0.0019 score: 27.5 coord: 294..327 e-value: 110.0 score: 5.9 coord: 99..132 e-value: 0.023 score: 23.9 coord: 179..212 e-value: 6.2 score: 15.8 coord: 213..246 e-value: 90.0 score: 6.6 coord: 328..361 e-value: 0.004 score: 26.4 coord: 31..64 e-value: 170.0 score: 4.1 coord: 145..178 e-value: 230.0 score: 2.9
IPR019734	Tetratricopeptide repeat	PFAM	PF13176	TPR_7	coord: 331..361 e-value: 0.0028 score: 17.5
IPR019734	Tetratricopeptide repeat	PROSITE	PS50005	TPR	coord: 213..246 score: 7.493
IPR019734	Tetratricopeptide repeat	PROSITE	PS50005	TPR	coord: 179..212 score: 7.906
IPR019734	Tetratricopeptide repeat	PROSITE	PS50005	TPR	coord: 31..64 score: 8.968
IPR019734	Tetratricopeptide repeat	PROSITE	PS50005	TPR	coord: 328..361 score: 9.027
IPR019734	Tetratricopeptide repeat	PROSITE	PS50005	TPR	coord: 99..132 score: 7.434
IPR019734	Tetratricopeptide repeat	PROSITE	PS50005	TPR	coord: 294..327 score: 5.015
IPR019734	Tetratricopeptide repeat	PROSITE	PS50005	TPR	coord: 145..178 score: 6.018
IPR019734	Tetratricopeptide repeat	PROSITE	PS50005	TPR	coord: 65..98 score: 8.349
IPR011990	Tetratricopeptide-like helical domain superfamily	GENE3D	G3DSA:1.25.40.10		coord: 29..379 e-value: 4.7E-102 score: 343.9
IPR011990	Tetratricopeptide-like helical domain superfamily	SUPERFAMILY	SSF48452	TPR-like	coord: 20..392
IPR036869	Chaperone J-domain superfamily	GENE3D	G3DSA:1.10.287.110		coord: 380..487 e-value: 1.6E-27 score: 98.2
IPR036869	Chaperone J-domain superfamily	SUPERFAMILY	SSF46565	Chaperone J-domain	coord: 376..477
IPR013026	Tetratricopeptide repeat-containing domain	PROSITE	PS50293	TPR_REGION	coord: 31..361 score: 34.693