DEP domain-containing protein

Overview


Name	DEP domain-containing protein
Smed ID	SMED30010473
Length (bp)	5196

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of DEP domain-containing protein (SMED30010473) t-SNE clustered cells

Violin plots show distribution of expression levels for DEP domain-containing protein (SMED30010473) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of DEP domain-containing protein (SMED30010473) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for DEP domain-containing protein (SMED30010473) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30010473

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30010473	SMESG000029435.1	Contig6675	uc_Smed_v2	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30010473	SMESG000029435.1	Contig6675	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30010473	SMESG000011963.1	Contig6675	uc_Smed_v2	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30010473	SMESG000011963.1	Contig6675	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
nervous system	SMED30010473	SMESG000029435.1	dd_Smed_v4_8467_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30010473	SMESG000029435.1	dd_Smed_v4_8467_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30010473	SMESG000029435.1	dd_Smed_v4_8467_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30010473	SMESG000029435.1	dd_Smed_v4_8467_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30010473	SMESG000029435.1	dd_Smed_v4_8467_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Human
Match: DEPDC5 (DEP domain containing 5, GATOR1 subcomplex subunit [Source:HGNC Symbol;Acc:HGNC:18423])

HSP 1 Score: 335.495 bits (859), Expect = 4.121e-100
Identity = 178/438 (40.64%), Postives = 276/438 (63.01%), Query Frame = 3

Query:   66 RLVFHKKL--KPEDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSS---SNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSS 1355
            +LV HKK     +D+++   K F  I  G ++EI    ND++   L+++ ++  +  QK+TIS D  +    +L P + +   V++   +TLD++++  +DQY+ R DM+R    + ++   +++K++F G  R    E+W   ++   GY   +TRVVFRS +++V+IFIQMS EMW+FD +G+LYF+KA+N F++DLF KW+  NC H++T+VLFSR FY   + +   +  + +I+ D  GRFYEDFY VVVQNER    EW  ++ T+K  F  Y   +   Q   F    N     S++   N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR    +TKQR+ D G+G+DLVC+GEQPLHAVPLF    +S+   S + D+ Y IP+WINHSFY S ++L       F PRIK++ +K +
Sbjct:    8 KLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAG-IRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRASIRQDHKGRFYEDFYKVVVQNERR--EEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDN-----STSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDD-YNIPHWINHSFYTSKSQLFC---NSFTPRIKLAGKKPA 431

[Close]

Query:   66 RLVFHKKL--KPEDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSS---SNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSS 1355
            +LV HKK     +D+++   K F  I  G ++EI    ND++   L+++ ++  +  QK+TIS D  +    +L P + +   V++   +TLD++++  +DQY+ R DM+R    + ++   +++K++F G  R    E+W   ++   GY   +TRVVFRS +++V+IFIQMS EMW+FD +G+LYF+KA+N F++DLF KW+  NC H++T+VLFSR FY   + +   +  + +I+ D  GRFYEDFY VVVQNER    EW  ++ T+K  F  Y   +   Q   F    N     S++   N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR    +TKQR+ D G+G+DLVC+GEQPLHAVPLF    +S+   S + D+ Y IP+WINHSFY S ++L       F PRIK++ +K +
Sbjct:    8 KLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAG-IRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRASIRQDHKGRFYEDFYKVVVQNERR--EEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDN-----STSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDD-YNIPHWINHSFYTSKSQLFC---NSFTPRIKLAGKKPA 431

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Human
Match: DEPDC5 (DEP domain containing 5, GATOR1 subcomplex subunit [Source:HGNC Symbol;Acc:HGNC:18423])

HSP 1 Score: 336.265 bits (861), Expect = 2.067e-99
Identity = 178/438 (40.64%), Postives = 276/438 (63.01%), Query Frame = 3

Query:   66 RLVFHKKL--KPEDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSS---SNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSS 1355
            +LV HKK     +D+++   K F  I  G ++EI    ND++   L+++ ++  +  QK+TIS D  +    +L P + +   V++   +TLD++++  +DQY+ R DM+R    + ++   +++K++F G  R    E+W   ++   GY   +TRVVFRS +++V+IFIQMS EMW+FD +G+LYF+KA+N F++DLF KW+  NC H++T+VLFSR FY   + +   +  + +I+ D  GRFYEDFY VVVQNER    EW  ++ T+K  F  Y   +   Q   F    N     S++   N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR    +TKQR+ D G+G+DLVC+GEQPLHAVPLF    +S+   S + D+ Y IP+WINHSFY S ++L       F PRIK++ +K +
Sbjct:    8 KLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAG-IRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRASIRQDHKGRFYEDFYKVVVQNERR--EEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDN-----STSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDD-YNIPHWINHSFYTSKSQLFC---NSFTPRIKLAGKKPA 431

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Human
Match: DEPDC5 (DEP domain containing 5, GATOR1 subcomplex subunit [Source:HGNC Symbol;Acc:HGNC:18423])

HSP 1 Score: 336.265 bits (861), Expect = 2.067e-99
Identity = 178/438 (40.64%), Postives = 276/438 (63.01%), Query Frame = 3

Query:   66 RLVFHKKL--KPEDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSS---SNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSS 1355
            +LV HKK     +D+++   K F  I  G ++EI    ND++   L+++ ++  +  QK+TIS D  +    +L P + +   V++   +TLD++++  +DQY+ R DM+R    + ++   +++K++F G  R    E+W   ++   GY   +TRVVFRS +++V+IFIQMS EMW+FD +G+LYF+KA+N F++DLF KW+  NC H++T+VLFSR FY   + +   +  + +I+ D  GRFYEDFY VVVQNER    EW  ++ T+K  F  Y   +   Q   F    N     S++   N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR    +TKQR+ D G+G+DLVC+GEQPLHAVPLF    +S+   S + D+ Y IP+WINHSFY S ++L       F PRIK++ +K +
Sbjct:    8 KLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAG-IRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRASIRQDHKGRFYEDFYKVVVQNERR--EEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDN-----STSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDD-YNIPHWINHSFYTSKSQLFC---NSFTPRIKLAGKKPA 431

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Human
Match: DEPDC5 (DEP domain containing 5, GATOR1 subcomplex subunit [Source:HGNC Symbol;Acc:HGNC:18423])

HSP 1 Score: 336.65 bits (862), Expect = 2.423e-98
Identity = 182/460 (39.57%), Postives = 283/460 (61.52%), Query Frame = 3

Query:   66 RLVFHKKL--KPEDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSS---SNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEK-------LAKPKDDNNFI 1400
            +LV HKK     +D+++   K F  I  G ++EI    ND++   L+++ ++  +  QK+TIS D  +    +L P + +   V++   +TLD++++  +DQY+ R DM+R    + ++   +++K++F G  R    E+W   ++   GY   +TRVVFRS +++V+IFIQMS EMW+FD +G+LYF+KA+N F++DLF KW+  NC H++T+VLFSR FY   + +   +  + +I+ D  GRFYEDFY VVVQNER    EW  ++ T+K  F  Y   +   Q   F    N     S++   N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR    +TKQR+ D G+G+DLVC+GEQPLHAVPLF    +S+   S + D+ Y IP+WINHSFY S ++L       F PRIK++ +K +  +        L  PK+  N +
Sbjct:    8 KLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAG-IRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRASIRQDHKGRFYEDFYKVVVQNERR--EEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDN-----STSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDD-YNIPHWINHSFYTSKSQLFC---NSFTPRIKLAGKKPASEKAKNGRDTSLGSPKESENAL 453

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Celegans
Match: T08A11.1 (pep chromosome:WBcel235:III:4248155:4263048:-1 gene:WBGene00011604.1 transcript:T08A11.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T08A11.1)

HSP 1 Score: 239.58 bits (610), Expect = 3.182e-63
Identity = 134/370 (36.22%), Postives = 215/370 (58.11%), Query Frame = 3

Query:  273 LTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAI-NFISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIK--IDENGRFYEDFYIVVVQNERYVGNEWR-KVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKL 1370
            L  N  +K  +   + ++LD + +  R+QY+SR+DMYR+   +   +  + +   +       +S+MW  G    SGY    TRVVFRS++S V IFIQM +EM + D  G+LY +K I  F+++LFLKW+  +C H ++I+L SR +        + D  KR +K   D  GR+Y+DFY ++ QNE Y   +W  K +K +    + Y +   Q Q+   +     +  +S+A D NFL+ +N+++N +  Y+ DR FE TG+  + +T G+GV +VDR    +TKQR+ D+G+ +D+VC+GEQPLHAVPLF+F            Y+IP+W+N+S+Y+      AI + +F PRI++     S  +K+
Sbjct:  351 LKQNDIVKCTLETVDTVSLDNVQLTFREQYMSRADMYRYRSCLIGRMTYVEEPKRYMN-INTRISDMWRKGSLVRSGYVTDKTRVVFRSSSSTVLIFIQMCSEMNQLDPQGDLYLEKCIKGFLTELFLKWKEQSCTHYVSIILCSRWYAIG----GVDDAAKRFMKGACDHRGRYYQDFYRLLFQNEHY--EDWADKQLKEINVGCSKYSS---QIQEKLKEMLPQVQFEVSTAADGNFLQVVNMSMNSFSMYHSDRRFETTGQQIIFVTPGNGVLHVDRDLVSLTKQRVIDMGISLDMVCLGEQPLHAVPLFVFHPIVGQMDKKCEYFIPHWMNYSYYQMARR-SAISV-QFRPRIQLPAAVLSAPKKM 708

HSP 2 Score: 69.707 bits (169), Expect = 2.402e-11
Identity = 72/299 (24.08%), Postives = 118/299 (39.46%), Query Frame = 3

Query: 4224 ESELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXX--XXXXXXXXQLVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESC-INYSSKDHLLNTQIKNTTKNVEGKQVYCD---SLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFYLDVK 5102
            +S LGE   W    Y   ++P  AF   ++W++ TG  +A+ +        K  + L PVP DPFAL    +S+PLR PI + L  E ++ ++D                       ER + L      IL RFGFI   C + +       ++   + TK +                   +++ +YIH +GGMF               I+L +     +                          F W+WN +L+ ++        E+FQD +L++FR  C++ ++ L Q Y D K
Sbjct: 1631 DSPLGE---WTRITYDHWFYPDTAFRITMKWVMGTGQTVADTVLSWFNKASKQGMSLYPVPEDPFALAQDTHSNPLRCPIRIQLK-EKVVAHSD-----------------------EREFLL-----KILFRFGFIDIGCNVKHDFSSPRTDSSSSDHTKALSSPSPTLQLEGDDGDLDDVTISMNYIHQAGGMF---------------ISLVLSENPNRPPF-----------------------FYWAWNHLLSNRYRGQ---CSEKFQDYLLSEFRAVCSDKNDTLTQLYSDFK 1856

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Fly
Match: Iml1 (gene:FBgn0035227 transcript:FBtr0333402)

HSP 1 Score: 338.576 bits (867), Expect = 1.837e-94
Identity = 180/424 (42.45%), Postives = 272/424 (64.15%), Query Frame = 3

Query:  102 DILFTAKDFSFISKGSLLEIYQ--QENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGY-FRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYK-TELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSL 1358
            D++   KD    + G ++EIY   +EN  H L++I   N +   +D IS +S + N+ K+ P  ++  +++    + LD ++I  +DQY+ RS+M+R   ++ ++ + ++KK+D+     R  V EMW  G+R  SG    +T++VFRS+TS+V++F+QMS+EMW+FD  G+LYF+KA+N F+++LF KW+  +C H++TIVLFSR FY   + +   ++++  ++ D  GRFYEDFY V +QNER   ++W  V+  L+  F +Y+ T L   ++ N        S   SA   NFLE LNI+LN +E +Y+DR F+RTG++ VVIT G GV++VDR  T+ITKQRI D GVG DLVC+GEQPLHAVPL  F  K ++  + + Y +P+WIN SFY S N  + I    FIPRIK+    S L
Sbjct:   20 DLVMNLKDHPNANVGDVVEIYAPDEENGTHLLLQITEFNGS-CGRDVISIESGIANAFKMRPYSNVVMRIVKPADVALDSIEITFKDQYMGRSEMWRLKTYLTDTCVYVNKKIDYNDMQIRCQVYEMWSQGERVASGVITEDTKIVFRSSTSMVYLFLQMSSEMWDFDIHGDLYFEKAVNGFLTELFQKWRKLSCNHEVTIVLFSRTFYAAKSLDEFPEHMRDCLQQDYKGRFYEDFYRVAIQNER--CDDWCTVLGQLRKLFTSYQATVLRYHERENMKIPPATNS---SATQGNFLEVLNISLNTFEKHYLDRTFDRTGQLSVVITPGVGVFSVDRELTNITKQRIIDNGVGSDLVCVGEQPLHAVPLLKFHNKDTTLTSADDYSLPHWINLSFY-STN--KKIVYSSFIPRIKLPLFGSQL 434

HSP 2 Score: 164.081 bits (414), Expect = 3.991e-40
Identity = 94/269 (34.94%), Postives = 142/269 (52.79%), Query Frame = 3

Query: 2199 GVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMIT---NPPALNYSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRR 2996
            GVDWKSLT+PA LPIT+DY+P  R L ++++ S+Y L+ +  N +   +   +RKPL   +V +E++ QRL QGFQ+I     PP  +  S+        +     ++ N  Y   +GRIFH I +   +I VT Y PRH     ++ Y Y    P  + + +S   F+T+ LE FNWN+ D YI   G            Y L+ SLK+WR R YLLP  +       +      RCDI+ D +       +E+F + +E ++K+KR+
Sbjct:  723 GVDWKSLTIPACLPITTDYFPDKRSLNNDYVISDYTLLPDDVNHDYAQSRAVYRKPLSTEEVCKEIVSQRLAQGFQLIVVDEKPPTASGCSS----GSAVQPVKLSRETNKEYLLSIGRIFHKISLSGSVITVTGYRPRHPYPPINVDYRYRFHAPQHETYEISGVNFTTEKLENFNWNHMDLYICTRGD---------VDYPLMESLKYWRYRMYLLPRENI-----VSKIASCQRCDIFPDVTADNTREQVEDFVRLIEAVSKLKRQ 973

HSP 3 Score: 135.191 bits (339), Expect = 2.976e-31
Identity = 98/307 (31.92%), Postives = 146/307 (47.56%), Query Frame = 3

Query: 4188 NGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ-LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKML-TRKW---TTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            N  +Y++  L+I+ ++  +R EWG  ++     P  AFE +V+W+ ++G  +A+ I  W +K +    LV VP DP A P +  SDPLRGPIF+PL    L   A                LFDEF +E R  R++  QEAIL +FGF+   C+                   +E K      L  +      + Y+H +G MFA+I   +     N  +  P+  E   +     +T + N  +         +GFLW+WN M+  +KW   T       E FQ +ML DFREFC+N+D RL  F+
Sbjct: 1225 NKRVYRQSHLEIDVNQKSDRMEWGHVKHHTVLQPRFAFEIVVEWVTSSGPIVADLIGGWMRKANQFNFLVSVPADPMAEPFTKKSDPLRGPIFIPLCTTFLPNGAA---------------LFDEFPEESRSDRMLFFQEAILGKFGFL--PCV-------------------LEKKYSVGKDLPKE------YQYVHCTGNMFALIRCATN----NYQVESPILKEANVTRCVYGHTNNTNVPK--------KVGFLWAWNHMIPNKKWKAQTINNSADGELFQLKMLKDFREFCSNSDQRLSTFW 1477

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Fly
Match: Iml1 (gene:FBgn0035227 transcript:FBtr0333401)

HSP 1 Score: 338.576 bits (867), Expect = 2.099e-94
Identity = 180/424 (42.45%), Postives = 272/424 (64.15%), Query Frame = 3

Query:  102 DILFTAKDFSFISKGSLLEIYQ--QENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGY-FRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYK-TELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSL 1358
            D++   KD    + G ++EIY   +EN  H L++I   N +   +D IS +S + N+ K+ P  ++  +++    + LD ++I  +DQY+ RS+M+R   ++ ++ + ++KK+D+     R  V EMW  G+R  SG    +T++VFRS+TS+V++F+QMS+EMW+FD  G+LYF+KA+N F+++LF KW+  +C H++TIVLFSR FY   + +   ++++  ++ D  GRFYEDFY V +QNER   ++W  V+  L+  F +Y+ T L   ++ N        S   SA   NFLE LNI+LN +E +Y+DR F+RTG++ VVIT G GV++VDR  T+ITKQRI D GVG DLVC+GEQPLHAVPL  F  K ++  + + Y +P+WIN SFY S N  + I    FIPRIK+    S L
Sbjct:   20 DLVMNLKDHPNANVGDVVEIYAPDEENGTHLLLQITEFNGS-CGRDVISIESGIANAFKMRPYSNVVMRIVKPADVALDSIEITFKDQYMGRSEMWRLKTYLTDTCVYVNKKIDYNDMQIRCQVYEMWSQGERVASGVITEDTKIVFRSSTSMVYLFLQMSSEMWDFDIHGDLYFEKAVNGFLTELFQKWRKLSCNHEVTIVLFSRTFYAAKSLDEFPEHMRDCLQQDYKGRFYEDFYRVAIQNER--CDDWCTVLGQLRKLFTSYQATVLRYHERENMKIPPATNS---SATQGNFLEVLNISLNTFEKHYLDRTFDRTGQLSVVITPGVGVFSVDRELTNITKQRIIDNGVGSDLVCVGEQPLHAVPLLKFHNKDTTLTSADDYSLPHWINLSFY-STN--KKIVYSSFIPRIKLPLFGSQL 434

HSP 2 Score: 162.925 bits (411), Expect = 9.209e-40
Identity = 96/291 (32.99%), Postives = 149/291 (51.20%), Query Frame = 3

Query: 2202 VDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMIT---NPPALNYSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRRSPNSKPKMSMPVIDNSSNLMNNP 3065
            VDWKSLT+PA LPIT+DY+P  R L ++++ S+Y L+ +  N +   +   +RKPL   +V +E++ QRL QGFQ+I     PP  +  S+        +     ++ N  Y   +GRIFH I +   +I VT Y PRH     ++ Y Y    P  + + +S   F+T+ LE FNWN+ D YI   G            Y L+ SLK+WR R YLLP  +       +      RCDI+ D +       +E+F + +E ++K+KR+        +  + +   N +N+P
Sbjct:  765 VDWKSLTIPACLPITTDYFPDKRSLNNDYVISDYTLLPDDVNHDYAQSRAVYRKPLSTEEVCKEIVSQRLAQGFQLIVVDEKPPTASGCSS----GSAVQPVKLSRETNKEYLLSIGRIFHKISLSGSVITVTGYRPRHPYPPINVDYRYRFHAPQHETYEISGVNFTTEKLENFNWNHMDLYICTRGD---------VDYPLMESLKYWRYRMYLLPRENI-----VSKIASCQRCDIFPDVTADNTREQVEDFVRLIEAVSKLKRQYARKARHDTPRITEKHHNQLNSP 1037

HSP 3 Score: 134.806 bits (338), Expect = 3.567e-31
Identity = 98/307 (31.92%), Postives = 146/307 (47.56%), Query Frame = 3

Query: 4188 NGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ-LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKML-TRKW---TTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            N  +Y++  L+I+ ++  +R EWG  ++     P  AFE +V+W+ ++G  +A+ I  W +K +    LV VP DP A P +  SDPLRGPIF+PL    L   A                LFDEF +E R  R++  QEAIL +FGF+   C+                   +E K      L  +      + Y+H +G MFA+I   +     N  +  P+  E   +     +T + N  +         +GFLW+WN M+  +KW   T       E FQ +ML DFREFC+N+D RL  F+
Sbjct: 1233 NKRVYRQSHLEIDVNQKSDRMEWGHVKHHTVLQPRFAFEIVVEWVTSSGPIVADLIGGWMRKANQFNFLVSVPADPMAEPFTKKSDPLRGPIFIPLCTTFLPNGAA---------------LFDEFPEESRSDRMLFFQEAILGKFGFL--PCV-------------------LEKKYSVGKDLPKE------YQYVHCTGNMFALIRCATN----NYQVESPILKEANVTRCVYGHTNNTNVPK--------KVGFLWAWNHMIPNKKWKAQTINNSADGELFQLKMLKDFREFCSNSDQRLSTFW 1485

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Fly
Match: Iml1 (gene:FBgn0035227 transcript:FBtr0072704)

HSP 1 Score: 338.191 bits (866), Expect = 2.262e-94
Identity = 180/424 (42.45%), Postives = 272/424 (64.15%), Query Frame = 3

Query:  102 DILFTAKDFSFISKGSLLEIYQ--QENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGY-FRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYK-TELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSL 1358
            D++   KD    + G ++EIY   +EN  H L++I   N +   +D IS +S + N+ K+ P  ++  +++    + LD ++I  +DQY+ RS+M+R   ++ ++ + ++KK+D+     R  V EMW  G+R  SG    +T++VFRS+TS+V++F+QMS+EMW+FD  G+LYF+KA+N F+++LF KW+  +C H++TIVLFSR FY   + +   ++++  ++ D  GRFYEDFY V +QNER   ++W  V+  L+  F +Y+ T L   ++ N        S   SA   NFLE LNI+LN +E +Y+DR F+RTG++ VVIT G GV++VDR  T+ITKQRI D GVG DLVC+GEQPLHAVPL  F  K ++  + + Y +P+WIN SFY S N  + I    FIPRIK+    S L
Sbjct:   20 DLVMNLKDHPNANVGDVVEIYAPDEENGTHLLLQITEFNGS-CGRDVISIESGIANAFKMRPYSNVVMRIVKPADVALDSIEITFKDQYMGRSEMWRLKTYLTDTCVYVNKKIDYNDMQIRCQVYEMWSQGERVASGVITEDTKIVFRSSTSMVYLFLQMSSEMWDFDIHGDLYFEKAVNGFLTELFQKWRKLSCNHEVTIVLFSRTFYAAKSLDEFPEHMRDCLQQDYKGRFYEDFYRVAIQNER--CDDWCTVLGQLRKLFTSYQATVLRYHERENMKIPPATNS---SATQGNFLEVLNISLNTFEKHYLDRTFDRTGQLSVVITPGVGVFSVDRELTNITKQRIIDNGVGSDLVCVGEQPLHAVPLLKFHNKDTTLTSADDYSLPHWINLSFY-STN--KKIVYSSFIPRIKLPLFGSQL 434

HSP 2 Score: 166.392 bits (420), Expect = 8.062e-41
Identity = 98/293 (33.45%), Postives = 151/293 (51.54%), Query Frame = 3

Query: 2199 GVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMIT---NPPALNYSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRRSPNSKPKMSMP-VIDNSSNLMNNP 3065
            GVDWKSLT+PA LPIT+DY+P  R L ++++ S+Y L+ +  N +   +   +RKPL   +V +E++ QRL QGFQ+I     PP  +  S+        +     ++ N  Y   +GRIFH I +   +I VT Y PRH     ++ Y Y    P  + + +S   F+T+ LE FNWN+ D YI   G            Y L+ SLK+WR R YLLP  +       +      RCDI+ D +       +E+F + +E ++K+KR+      +   P + +   N +N+P
Sbjct:  723 GVDWKSLTIPACLPITTDYFPDKRSLNNDYVISDYTLLPDDVNHDYAQSRAVYRKPLSTEEVCKEIVSQRLAQGFQLIVVDEKPPTASGCSS----GSAVQPVKLSRETNKEYLLSIGRIFHKISLSGSVITVTGYRPRHPYPPINVDYRYRFHAPQHETYEISGVNFTTEKLENFNWNHMDLYICTRGD---------VDYPLMESLKYWRYRMYLLPRENI-----VSKIASCQRCDIFPDVTADNTREQVEDFVRLIEAVSKLKRQYARKARQHDTPRITEKHHNQLNSP 997

HSP 3 Score: 135.191 bits (339), Expect = 3.059e-31
Identity = 98/307 (31.92%), Postives = 146/307 (47.56%), Query Frame = 3

Query: 4188 NGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ-LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKML-TRKW---TTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            N  +Y++  L+I+ ++  +R EWG  ++     P  AFE +V+W+ ++G  +A+ I  W +K +    LV VP DP A P +  SDPLRGPIF+PL    L   A                LFDEF +E R  R++  QEAIL +FGF+   C+                   +E K      L  +      + Y+H +G MFA+I   +     N  +  P+  E   +     +T + N  +         +GFLW+WN M+  +KW   T       E FQ +ML DFREFC+N+D RL  F+
Sbjct: 1193 NKRVYRQSHLEIDVNQKSDRMEWGHVKHHTVLQPRFAFEIVVEWVTSSGPIVADLIGGWMRKANQFNFLVSVPADPMAEPFTKKSDPLRGPIFIPLCTTFLPNGAA---------------LFDEFPEESRSDRMLFFQEAILGKFGFL--PCV-------------------LEKKYSVGKDLPKE------YQYVHCTGNMFALIRCATN----NYQVESPILKEANVTRCVYGHTNNTNVPK--------KVGFLWAWNHMIPNKKWKAQTINNSADGELFQLKMLKDFREFCSNSDQRLSTFW 1445

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Fly
Match: Iml1 (gene:FBgn0035227 transcript:FBtr0072703)

HSP 1 Score: 338.576 bits (867), Expect = 2.336e-94
Identity = 180/424 (42.45%), Postives = 272/424 (64.15%), Query Frame = 3

Query:  102 DILFTAKDFSFISKGSLLEIYQ--QENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGY-FRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYK-TELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSL 1358
            D++   KD    + G ++EIY   +EN  H L++I   N +   +D IS +S + N+ K+ P  ++  +++    + LD ++I  +DQY+ RS+M+R   ++ ++ + ++KK+D+     R  V EMW  G+R  SG    +T++VFRS+TS+V++F+QMS+EMW+FD  G+LYF+KA+N F+++LF KW+  +C H++TIVLFSR FY   + +   ++++  ++ D  GRFYEDFY V +QNER   ++W  V+  L+  F +Y+ T L   ++ N        S   SA   NFLE LNI+LN +E +Y+DR F+RTG++ VVIT G GV++VDR  T+ITKQRI D GVG DLVC+GEQPLHAVPL  F  K ++  + + Y +P+WIN SFY S N  + I    FIPRIK+    S L
Sbjct:   20 DLVMNLKDHPNANVGDVVEIYAPDEENGTHLLLQITEFNGS-CGRDVISIESGIANAFKMRPYSNVVMRIVKPADVALDSIEITFKDQYMGRSEMWRLKTYLTDTCVYVNKKIDYNDMQIRCQVYEMWSQGERVASGVITEDTKIVFRSSTSMVYLFLQMSSEMWDFDIHGDLYFEKAVNGFLTELFQKWRKLSCNHEVTIVLFSRTFYAAKSLDEFPEHMRDCLQQDYKGRFYEDFYRVAIQNER--CDDWCTVLGQLRKLFTSYQATVLRYHERENMKIPPATNS---SATQGNFLEVLNISLNTFEKHYLDRTFDRTGQLSVVITPGVGVFSVDRELTNITKQRIIDNGVGSDLVCVGEQPLHAVPLLKFHNKDTTLTSADDYSLPHWINLSFY-STN--KKIVYSSFIPRIKLPLFGSQL 434

HSP 2 Score: 161.384 bits (407), Expect = 2.901e-39
Identity = 93/268 (34.70%), Postives = 141/268 (52.61%), Query Frame = 3

Query: 2202 VDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMIT---NPPALNYSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRR 2996
            VDWKSLT+PA LPIT+DY+P  R L ++++ S+Y L+ +  N +   +   +RKPL   +V +E++ QRL QGFQ+I     PP  +  S+        +     ++ N  Y   +GRIFH I +   +I VT Y PRH     ++ Y Y    P  + + +S   F+T+ LE FNWN+ D YI   G            Y L+ SLK+WR R YLLP  +       +      RCDI+ D +       +E+F + +E ++K+KR+
Sbjct:  765 VDWKSLTIPACLPITTDYFPDKRSLNNDYVISDYTLLPDDVNHDYAQSRAVYRKPLSTEEVCKEIVSQRLAQGFQLIVVDEKPPTASGCSS----GSAVQPVKLSRETNKEYLLSIGRIFHKISLSGSVITVTGYRPRHPYPPINVDYRYRFHAPQHETYEISGVNFTTEKLENFNWNHMDLYICTRGD---------VDYPLMESLKYWRYRMYLLPRENI-----VSKIASCQRCDIFPDVTADNTREQVEDFVRLIEAVSKLKRQ 1014

HSP 3 Score: 134.806 bits (338), Expect = 3.649e-31
Identity = 98/307 (31.92%), Postives = 146/307 (47.56%), Query Frame = 3

Query: 4188 NGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ-LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKML-TRKW---TTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            N  +Y++  L+I+ ++  +R EWG  ++     P  AFE +V+W+ ++G  +A+ I  W +K +    LV VP DP A P +  SDPLRGPIF+PL    L   A                LFDEF +E R  R++  QEAIL +FGF+   C+                   +E K      L  +      + Y+H +G MFA+I   +     N  +  P+  E   +     +T + N  +         +GFLW+WN M+  +KW   T       E FQ +ML DFREFC+N+D RL  F+
Sbjct: 1266 NKRVYRQSHLEIDVNQKSDRMEWGHVKHHTVLQPRFAFEIVVEWVTSSGPIVADLIGGWMRKANQFNFLVSVPADPMAEPFTKKSDPLRGPIFIPLCTTFLPNGAA---------------LFDEFPEESRSDRMLFFQEAILGKFGFL--PCV-------------------LEKKYSVGKDLPKE------YQYVHCTGNMFALIRCATN----NYQVESPILKEANVTRCVYGHTNNTNVPK--------KVGFLWAWNHMIPNKKWKAQTINNSADGELFQLKMLKDFREFCSNSDQRLSTFW 1518

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Fly
Match: Iml1 (gene:FBgn0035227 transcript:FBtr0072705)

HSP 1 Score: 338.191 bits (866), Expect = 2.560e-94
Identity = 180/424 (42.45%), Postives = 272/424 (64.15%), Query Frame = 3

Query:  102 DILFTAKDFSFISKGSLLEIYQ--QENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGY-FRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYK-TELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSL 1358
            D++   KD    + G ++EIY   +EN  H L++I   N +   +D IS +S + N+ K+ P  ++  +++    + LD ++I  +DQY+ RS+M+R   ++ ++ + ++KK+D+     R  V EMW  G+R  SG    +T++VFRS+TS+V++F+QMS+EMW+FD  G+LYF+KA+N F+++LF KW+  +C H++TIVLFSR FY   + +   ++++  ++ D  GRFYEDFY V +QNER   ++W  V+  L+  F +Y+ T L   ++ N        S   SA   NFLE LNI+LN +E +Y+DR F+RTG++ VVIT G GV++VDR  T+ITKQRI D GVG DLVC+GEQPLHAVPL  F  K ++  + + Y +P+WIN SFY S N  + I    FIPRIK+    S L
Sbjct:   20 DLVMNLKDHPNANVGDVVEIYAPDEENGTHLLLQITEFNGS-CGRDVISIESGIANAFKMRPYSNVVMRIVKPADVALDSIEITFKDQYMGRSEMWRLKTYLTDTCVYVNKKIDYNDMQIRCQVYEMWSQGERVASGVITEDTKIVFRSSTSMVYLFLQMSSEMWDFDIHGDLYFEKAVNGFLTELFQKWRKLSCNHEVTIVLFSRTFYAAKSLDEFPEHMRDCLQQDYKGRFYEDFYRVAIQNER--CDDWCTVLGQLRKLFTSYQATVLRYHERENMKIPPATNS---SATQGNFLEVLNISLNTFEKHYLDRTFDRTGQLSVVITPGVGVFSVDRELTNITKQRIIDNGVGSDLVCVGEQPLHAVPLLKFHNKDTTLTSADDYSLPHWINLSFY-STN--KKIVYSSFIPRIKLPLFGSQL 434

HSP 2 Score: 164.081 bits (414), Expect = 4.711e-40
Identity = 94/269 (34.94%), Postives = 142/269 (52.79%), Query Frame = 3

Query: 2199 GVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMIT---NPPALNYSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRR 2996
            GVDWKSLT+PA LPIT+DY+P  R L ++++ S+Y L+ +  N +   +   +RKPL   +V +E++ QRL QGFQ+I     PP  +  S+        +     ++ N  Y   +GRIFH I +   +I VT Y PRH     ++ Y Y    P  + + +S   F+T+ LE FNWN+ D YI   G            Y L+ SLK+WR R YLLP  +       +      RCDI+ D +       +E+F + +E ++K+KR+
Sbjct:  723 GVDWKSLTIPACLPITTDYFPDKRSLNNDYVISDYTLLPDDVNHDYAQSRAVYRKPLSTEEVCKEIVSQRLAQGFQLIVVDEKPPTASGCSS----GSAVQPVKLSRETNKEYLLSIGRIFHKISLSGSVITVTGYRPRHPYPPINVDYRYRFHAPQHETYEISGVNFTTEKLENFNWNHMDLYICTRGD---------VDYPLMESLKYWRYRMYLLPRENI-----VSKIASCQRCDIFPDVTADNTREQVEDFVRLIEAVSKLKRQ 973

HSP 3 Score: 134.806 bits (338), Expect = 4.151e-31
Identity = 98/307 (31.92%), Postives = 146/307 (47.56%), Query Frame = 3

Query: 4188 NGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ-LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKML-TRKW---TTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            N  +Y++  L+I+ ++  +R EWG  ++     P  AFE +V+W+ ++G  +A+ I  W +K +    LV VP DP A P +  SDPLRGPIF+PL    L   A                LFDEF +E R  R++  QEAIL +FGF+   C+                   +E K      L  +      + Y+H +G MFA+I   +     N  +  P+  E   +     +T + N  +         +GFLW+WN M+  +KW   T       E FQ +ML DFREFC+N+D RL  F+
Sbjct: 1194 NKRVYRQSHLEIDVNQKSDRMEWGHVKHHTVLQPRFAFEIVVEWVTSSGPIVADLIGGWMRKANQFNFLVSVPADPMAEPFTKKSDPLRGPIFIPLCTTFLPNGAA---------------LFDEFPEESRSDRMLFFQEAILGKFGFL--PCV-------------------LEKKYSVGKDLPKE------YQYVHCTGNMFALIRCATN----NYQVESPILKEANVTRCVYGHTNNTNVPK--------KVGFLWAWNHMIPNKKWKAQTINNSADGELFQLKMLKDFREFCSNSDQRLSTFW 1446

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Zebrafish
Match: depdc5 (DEP domain containing 5, GATOR1 subcomplex subunit [Source:ZFIN;Acc:ZDB-GENE-091204-356])

HSP 1 Score: 342.813 bits (878), Expect = 1.823e-95
Identity = 181/458 (39.52%), Postives = 283/458 (61.79%), Query Frame = 3

Query:   66 RLVFHKKL--KPEDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKS---SSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFE-------KSSLIEKLAKPKDDNN 1394
            +LV HKK     +D+++   K F  +  G ++EI    ND++   L+++ ++  +  QK+TIS D  +  + KL   + +   +++   +TLD++++  +DQY+ R DM+R    + ++   +++K++F G  R   SE+W  G++   GY   +TRVVFRS +++V+IFIQMS EMW+FD +G+LYF+KA+N F+SDLF KW+  NC H++T+VLFSR FY     E   ++ + +++ D  GR+YEDFY VV QNER   +EW  ++ T+K  F  Y   +     + F C  N     S++   N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR    +TKQR+ D G+G+DLVC+GEQPLHAVPLF    ++    S I D+ Y +P+WINHSFY S ++        F PRIK++ +       K+S    L  PKD  N
Sbjct:   12 KLVVHKKGFGGSDDELMMNPKVFPQVKLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETISVDQTVAQAFKLRAYQDVIINIVDPKEVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYVTQKVEFAG-IRAQASELWVKGEKVTCGYISEDTRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLSDLFAKWKEKNCSHEVTVVLFSRTFYSAKTLEEFPESQRASVRQDHEGRYYEDFYRVVAQNERR--DEWMSLLVTIKKLFIQYPVLVRLKGADGFPCGHN-----STSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRTVHGDSRIGDD-YNLPHWINHSFYTSKSQNSC---SCFTPRIKLAGKKVHAEKAKNSKEHSLGAPKDAEN 455

HSP 2 Score: 143.665 bits (361), Expect = 9.841e-34
Identity = 133/516 (25.78%), Postives = 211/516 (40.89%), Query Frame = 3

Query: 3564 VRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNIXXXXXXXXXXXXXXXDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ--LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRE----SCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            + +LE + +   G+  L          F S E VHW +S ++ +     AV  +QK++    I HAS  +   FVYGF FY +           +D  N                  +   + S   +E   ++          +R + E +F+      + +P D      FL+  +P +       H +     G       L        K V LD++ +   +R EW    Y  N+    AFE  + W+  T   L E +  W +K +     LVPV   PFAL S +  DPLR  +F+PL+I+CL++                D LF+ F  E    R+ L QEAIL RFGF+++    S  N+ S++                                   YIH +G +F  +P YSK +  +         +  + N ++S  + +   E+        +G+ W++N MLT+ W TG ++ DE+  DR+L DF +FC N DNRL  F+
Sbjct: 1139 MEILEAIKHPTTGVQLLPEQRGLPPNCFVSAEVVHWLVSTVENVATQGIAVEIMQKMLEEGLITHASGDAMRTFVYGFYFYRI-----------VDKDN--------EKAPLTQLPPAGANVWSAAALEDFALF----------QRKWFEVAFVM----EERRPCDLP---AFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQKTVTLDVDVNNRSDRTEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMVQGWHRKAASCGFLLVPVLEVPFALSSYLYGDPLRAQLFIPLNIQCLLKEGS-------------DNLFEGFEPETYWDRMQLFQEAILTRFGFVQDKFSASAFNFPSENKP--------------------------------QYIHVTGTVFLQLP-YSKRKYSSG--------QRRRRNSTTSTNQSLFGSEE-------RVGYNWAYNTMLTKAWRTG-VLGDEKLADRLLRDFTDFCANKDNRLVTFW 1556

HSP 3 Score: 137.502 bits (345), Expect = 7.359e-32
Identity = 92/279 (32.97%), Postives = 147/279 (52.69%), Query Frame = 3

Query: 2196 IGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNP-----PALN---YSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDS-KDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQN--------SLIEEFFKFLEGIN 2981
            +GVDWKSLT PA LP+T+DY+P  + L++++ E  Y L+ ++     +         +  H VF+E I QRL QG+Q+I  P     PA+     SS ++       S  K +++ ++Y   +GR FH + +K  +I VT+Y P++      I Y+Y L  P +   FM    +FS + LE++ WNY D YI + G      ++D   + LI SLKFWR+RF LLP   A         + +   D+Y + +   ++        +L++ F +FLEG+N
Sbjct:  723 VGVDWKSLTTPACLPLTTDYFPDRQTLQNDYTEGCYDLLPHTDLERRDDETPV----MTAHQVFEEFICQRLMQGYQIIVQPNRKPQPAIAPPLSSSPLY--SRGLVSRRKPEEEESLYWLSMGRTFHKVCLKDKIITVTRYLPKYPYESTQIQYSYNLCPPHADAHFMPFWVEFSHERLEEYKWNYLDQYICSAG------SED---FSLIDSLKFWRTRFLLLPAGGA-----RRVADGEGHWDVYGEGAGAGRDGLAGTGDWTLLDGFIRFLEGLN 981

HSP 4 Score: 68.1662 bits (165), Expect = 1.178e-10
Identity = 27/57 (47.37%), Postives = 40/57 (70.18%), Query Frame = 3

Query: 1611 RKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKN 1781
            ++AL NPFAP+R  ++ TSN RRW H FP+  + +PIQ+HHQ   N  +L G E+++
Sbjct:  595 QRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEPIQIHHQTRQNMAELQGSEQRD 651

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Zebrafish
Match: depdc5 (DEP domain containing 5, GATOR1 subcomplex subunit [Source:ZFIN;Acc:ZDB-GENE-091204-356])

HSP 1 Score: 342.813 bits (878), Expect = 2.189e-95
Identity = 181/458 (39.52%), Postives = 283/458 (61.79%), Query Frame = 3

Query:   66 RLVFHKKL--KPEDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKS---SSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFE-------KSSLIEKLAKPKDDNN 1394
            +LV HKK     +D+++   K F  +  G ++EI    ND++   L+++ ++  +  QK+TIS D  +  + KL   + +   +++   +TLD++++  +DQY+ R DM+R    + ++   +++K++F G  R   SE+W  G++   GY   +TRVVFRS +++V+IFIQMS EMW+FD +G+LYF+KA+N F+SDLF KW+  NC H++T+VLFSR FY     E   ++ + +++ D  GR+YEDFY VV QNER   +EW  ++ T+K  F  Y   +     + F C  N     S++   N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR    +TKQR+ D G+G+DLVC+GEQPLHAVPLF    ++    S I D+ Y +P+WINHSFY S ++        F PRIK++ +       K+S    L  PKD  N
Sbjct:   12 KLVVHKKGFGGSDDELMMNPKVFPQVKLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETISVDQTVAQAFKLRAYQDVIINIVDPKEVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYVTQKVEFAG-IRAQASELWVKGEKVTCGYISEDTRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLSDLFAKWKEKNCSHEVTVVLFSRTFYSAKTLEEFPESQRASVRQDHEGRYYEDFYRVVAQNERR--DEWMSLLVTIKKLFIQYPVLVRLKGADGFPCGHN-----STSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRTVHGDSRIGDD-YNLPHWINHSFYTSKSQNSC---SCFTPRIKLAGKKVHAEKAKNSKEHSLGAPKDAEN 455

HSP 2 Score: 143.665 bits (361), Expect = 1.234e-33
Identity = 133/516 (25.78%), Postives = 211/516 (40.89%), Query Frame = 3

Query: 3564 VRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNIXXXXXXXXXXXXXXXDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ--LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRE----SCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            + +LE + +   G+  L          F S E VHW +S ++ +     AV  +QK++    I HAS  +   FVYGF FY +           +D  N                  +   + S   +E   ++          +R + E +F+      + +P D      FL+  +P +       H +     G       L        K V LD++ +   +R EW    Y  N+    AFE  + W+  T   L E +  W +K +     LVPV   PFAL S +  DPLR  +F+PL+I+CL++                D LF+ F  E    R+ L QEAIL RFGF+++    S  N+ S++                                   YIH +G +F  +P YSK +  +         +  + N ++S  + +   E+        +G+ W++N MLT+ W TG ++ DE+  DR+L DF +FC N DNRL  F+
Sbjct: 1174 MEILEAIKHPTTGVQLLPEQRGLPPNCFVSAEVVHWLVSTVENVATQGIAVEIMQKMLEEGLITHASGDAMRTFVYGFYFYRI-----------VDKDN--------EKAPLTQLPPAGANVWSAAALEDFALF----------QRKWFEVAFVM----EERRPCDLP---AFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQKTVTLDVDVNNRSDRTEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMVQGWHRKAASCGFLLVPVLEVPFALSSYLYGDPLRAQLFIPLNIQCLLKEGS-------------DNLFEGFEPETYWDRMQLFQEAILTRFGFVQDKFSASAFNFPSENKP--------------------------------QYIHVTGTVFLQLP-YSKRKYSSG--------QRRRRNSTTSTNQSLFGSEE-------RVGYNWAYNTMLTKAWRTG-VLGDEKLADRLLRDFTDFCANKDNRLVTFW 1591

HSP 3 Score: 137.502 bits (345), Expect = 8.053e-32
Identity = 92/279 (32.97%), Postives = 147/279 (52.69%), Query Frame = 3

Query: 2196 IGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNP-----PALN---YSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDS-KDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQN--------SLIEEFFKFLEGIN 2981
            +GVDWKSLT PA LP+T+DY+P  + L++++ E  Y L+ ++     +         +  H VF+E I QRL QG+Q+I  P     PA+     SS ++       S  K +++ ++Y   +GR FH + +K  +I VT+Y P++      I Y+Y L  P +   FM    +FS + LE++ WNY D YI + G      ++D   + LI SLKFWR+RF LLP   A         + +   D+Y + +   ++        +L++ F +FLEG+N
Sbjct:  737 VGVDWKSLTTPACLPLTTDYFPDRQTLQNDYTEGCYDLLPHTDLERRDDETPV----MTAHQVFEEFICQRLMQGYQIIVQPNRKPQPAIAPPLSSSPLY--SRGLVSRRKPEEEESLYWLSMGRTFHKVCLKDKIITVTRYLPKYPYESTQIQYSYNLCPPHADAHFMPFWVEFSHERLEEYKWNYLDQYICSAG------SED---FSLIDSLKFWRTRFLLLPAGGA-----RRVADGEGHWDVYGEGAGAGRDGLAGTGDWTLLDGFIRFLEGLN 995

HSP 4 Score: 68.1662 bits (165), Expect = 1.135e-10
Identity = 27/57 (47.37%), Postives = 40/57 (70.18%), Query Frame = 3

Query: 1611 RKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKN 1781
            ++AL NPFAP+R  ++ TSN RRW H FP+  + +PIQ+HHQ   N  +L G E+++
Sbjct:  595 QRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEPIQIHHQTRQNMAELQGSEQRD 651

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Zebrafish
Match: depdc5 (DEP domain containing 5, GATOR1 subcomplex subunit [Source:ZFIN;Acc:ZDB-GENE-091204-356])

HSP 1 Score: 80.4925 bits (197), Expect = 8.559e-16
Identity = 57/171 (33.33%), Postives = 83/171 (48.54%), Query Frame = 3

Query: 4203 KKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ--LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRE----SCINYSSKDHLLNTQIKNTT 4694
            K V LD++ +   +R EW    Y  N+    AFE  + W+  T   L E +  W +K +     LVPV   PFAL S +  DPLR  +F+PL+I+CL++                D LF+ F  E    R+ L QEAIL RFGF+++    S  N+ S++      +  T 
Sbjct:   87 KTVTLDVDVNNRSDRTEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMVQGWHRKAASCGFLLVPVLEVPFALSSYLYGDPLRAQLFIPLNIQCLLKEGS-------------DNLFEGFEPETYWDRMQLFQEAILTRFGFVQDKFSASAFNFPSENKPQYIHVTGTV 244

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000047719.1 (DEP domain containing 5 [Source:NCBI gene;Acc:100498286])

HSP 1 Score: 347.821 bits (891), Expect = 3.053e-97
Identity = 219/630 (34.76%), Postives = 339/630 (53.81%), Query Frame = 3

Query:   96 EDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKI--DENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSS---SNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNF------------IYEIP-----ENSLNF--VR--KLSKPEIVSDNISGVISTSNNCERGGLYHGSYGSHNSKDDTFINPIKPGHK-----------------RIIQSDHR---------------------------KALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYG 1766
            +D+++   K F +I+ G ++EI    ND++   L+++ ++  +  QK+T+S D  +    +L P + +   V++   +TLD++++  +DQY+ R DM+R     +  VL  +    F    R  V E+W   ++   GY   +TRVVFRS +++V+IFIQMS+E+W+FD +G+LYF+KA+N F++DLF KW++ NC H++T+VLFSR FY   N E+  +   RN  +  D  GRFYEDFY VVVQNER    EW  ++ T+K  F  Y   +       F    N     S+++  N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR+   +TKQR+ D G+G+DLVC+GEQPLHAVPLF    +SS   S + D+ Y IP+WINHSFY S  + Q +    F PRIK++  K  ++  L   + +N              ++ +P     + S+ F  VR  ++ K     D     +S     E G   +    S     +  + P    H+                 R+I+S  R                           +AL NPFAP+R  ++ TSN RRW H FP+  + + IQ+HHQ   N  +L G
Sbjct:   19 DDELVINPKVFPYINLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETVSIDQTVAQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLK---KIPVLSQTCYWLFL-ICRAQVGELWVKSEKVTCGYISEDTRVVFRSTSAMVYIFIQMSSELWDFDIYGDLYFEKAVNGFLADLFNKWKDKNCSHEVTVVLFSRTFYDAKNIEDFPE-AHRNASVMQDHKGRFYEDFYKVVVQNERR--EEWTSLLVTIKKLFIQYPVLVRLENAEGFPPGHN-----STSDQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFQVDRSLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSSPGDSRLGDD-YNIPHWINHSFYTS--QSQPLN-NSFTPRIKLAPRK--VLASLYPKETENALPIQVDYDAYDSQVFRLPGPSRAQRSITFRAVRETQVRKSSCSYDTSCSPVSRPFTAEEGRSQNSDESSLGKLSNILLIPRPHLHQYEASSSLGYTSTRDFLERMIESQQRDSSAPGRFHVGSAESMLHVRPGGYHPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQG 628

HSP 2 Score: 141.354 bits (355), Expect = 8.178e-33
Identity = 93/271 (34.32%), Postives = 137/271 (50.55%), Query Frame = 3

Query: 2196 IGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNP--PALNYSSTIFXXXXXXXXXXXXXXXXA----IYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSK-DFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQN--SLIEEFFKFLEGIN 2981
            +GVDWKSLT PA LP+T+DY+P  + L++++ E  Y L+  +     +         +    VF+E I QRL QG+Q+I  P  P    S               +    A     Y   +GR FH + +K  +I VT+Y P++    A I+Y Y L    S+ DF+ S  +FS + LE + WNY D YI + G      ++D   + LI SLKFWR+RF LLP+              + RCDIY ++   EQ    L++ F +F+EG+N
Sbjct:  689 VGVDWKSLTTPACLPLTTDYFPDRQSLQNDYTEGCYDLLPEADLDRRDEEGAQ----MTAQQVFEEFICQRLMQGYQIIVQPKHPKAISSVPPPLSSSPLYRRGLVSRNRAEEENQYWLSMGRTFHKVTLKDKIITVTRYLPKYPYESAQISYMYSLCPSHSECDFVSSWVEFSHERLEDYKWNYLDQYICSAG------SED---FSLIESLKFWRTRFLLLPSCVG---PTKRITEGEQRCDIYGERPRSEQEEAQLLDGFLRFVEGLN 943

HSP 3 Score: 135.576 bits (340), Expect = 4.560e-31
Identity = 139/522 (26.63%), Postives = 214/522 (41.00%), Query Frame = 3

Query: 3543 LSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNIXXXXXXXXXXXXXXXDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ--LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKW---TTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            L  ++    +LE M +   G+  L   +      F S EAVHW ++ +  +     A+  +QK++  +YI HAS  +   F+YGF  Y +                              A  E D   ++ N ++    +  +ME     +R + E + +   L     P        FL+  +P +       H +     G       L        + V LD++ +   +R EW    Y  N+  T AFE  + W+ AT   L E +  W +K       LVPV   PF+LPS +  DPLR  +F+PL+I CL++  +             D LF+ F  E    R+ LLQE I  RFGFI++    YS+      ++ K                           YIH +G +F  +P YSK              +  + N +SS T+++  +E         IG+ W++N MLT+ W    TG    DE+F DR+L DF +FC N DNRL  F+
Sbjct: 1038 LPTTASLSEILEAMKHPTTGIPLLSEQKCLPPGCFISAEAVHWLVNNISWVQSQVMAMDIMQKMLEEQYITHASGETFRTFIYGFYLYKI-----------------------------PADKEPD---RASNLVQPCVWHSTAMEDFTAFQRKWFEVALVEEELLHSEIPP-------FLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSSYYHGNFSLTAAFEIKLHWMAATAAMLFEMVQGWHRKAPSCGFLLVPVVEGPFSLPSYLYGDPLRAQLFIPLNISCLVKAEN-------------DHLFEGFEPETYWERMYLLQEVIAYRFGFIQD---KYSASAFNFPSENKP-------------------------QYIHVTGTVFLQLP-YSKR----------KGQQRRRRNSTSSSTQNLFGEE--------RIGYNWAYNTMLTKTWRSIGTG----DERFADRLLKDFTDFCANRDNRLGTFW 1456

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000047756.1 (DEP domain containing 5 [Source:NCBI gene;Acc:100498286])

HSP 1 Score: 335.109 bits (858), Expect = 2.989e-93
Identity = 212/613 (34.58%), Postives = 330/613 (53.83%), Query Frame = 3

Query:   96 EDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKI--DENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSS---SNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNF------------IYEIP-----ENSLNF--VR--KLSKPEIVSDNISGVISTSNNCERGGLYHGSYGSHNSKDDTFINPIKPGHK-----------------RIIQSDHR---------------------------KALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNK 1715
            +D+++   K F +I+ G ++EI    ND++   L+++ ++  +  QK+T+S D  +    +L P + +   V++   +TLD++++  +DQY+ R DM+R     +  VL  +    F    R  V E+W   ++   GY   +TRVVFRS +++V+IFIQMS+E+W+FD +G+LYF+KA+N F++DLF KW++ NC H++T+VLFSR FY   N E+  +   RN  +  D  GRFYEDFY VVVQNER    EW  ++ T+K  F  Y   +       F    N     S+++  N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR+   +TKQR+ D G+G+DLVC+GEQPLHAVPLF    +SS   S + D+ Y IP+WINHSFY S  + Q +    F PRIK++  K  ++  L   + +N              ++ +P     + S+ F  VR  ++ K     D     +S     E G   +    S     +  + P    H+                 R+I+S  R                           +AL NPFAP+R  ++ TSN RRW H FP+  N++
Sbjct:   19 DDELVINPKVFPYINLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETVSIDQTVAQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLK---KIPVLSQTCYWLFL-ICRAQVGELWVKSEKVTCGYISEDTRVVFRSTSAMVYIFIQMSSELWDFDIYGDLYFEKAVNGFLADLFNKWKDKNCSHEVTVVLFSRTFYDAKNIEDFPE-AHRNASVMQDHKGRFYEDFYKVVVQNERR--EEWTSLLVTIKKLFIQYPVLVRLENAEGFPPGHN-----STSDQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFQVDRSLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSSPGDSRLGDD-YNIPHWINHSFYTS--QSQPLN-NSFTPRIKLAPRK--VLASLYPKETENALPIQVDYDAYDSQVFRLPGPSRAQRSITFRAVRETQVRKSSCSYDTSCSPVSRPFTAEEGRSQNSDESSLGKLSNILLIPRPHLHQYEASSSLGYTSTRDFLERMIESQQRDSSAPGRFHVGSAESMLHVRPGGYHPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGSNHR 611

HSP 2 Score: 141.354 bits (355), Expect = 6.589e-33
Identity = 93/271 (34.32%), Postives = 137/271 (50.55%), Query Frame = 3

Query: 2196 IGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNP--PALNYSSTIFXXXXXXXXXXXXXXXXA----IYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSK-DFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQN--SLIEEFFKFLEGIN 2981
            +GVDWKSLT PA LP+T+DY+P  + L++++ E  Y L+  +     +         +    VF+E I QRL QG+Q+I  P  P    S               +    A     Y   +GR FH + +K  +I VT+Y P++    A I+Y Y L    S+ DF+ S  +FS + LE + WNY D YI + G      ++D   + LI SLKFWR+RF LLP+              + RCDIY ++   EQ    L++ F +F+EG+N
Sbjct:  643 VGVDWKSLTTPACLPLTTDYFPDRQSLQNDYTEGCYDLLPEADLDRRDEEGAQ----MTAQQVFEEFICQRLMQGYQIIVQPKHPKAISSVPPPLSSSPLYRRGLVSRNRAEEENQYWLSMGRTFHKVTLKDKIITVTRYLPKYPYESAQISYMYSLCPSHSECDFVSSWVEFSHERLEDYKWNYLDQYICSAG------SED---FSLIESLKFWRTRFLLLPSCVG---PTKRITEGEQRCDIYGERPRSEQEEAQLLDGFLRFVEGLN 897

HSP 3 Score: 130.183 bits (326), Expect = 2.138e-29
Identity = 133/488 (27.25%), Postives = 202/488 (41.39%), Query Frame = 3

Query: 3645 FTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNIXXXXXXXXXXXXXXXDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ--LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKW---TTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            F S EAVHW ++ +  +     A+  +QK++  +YI HAS  +   F+YGF  Y +                              A  E D   ++ N ++    +  +ME     +R + E + +   L     P        FL+  +P +       H +     G       L        + V LD++ +   +R EW    Y  N+  T AFE  + W+ AT   L E +  W +K       LVPV   PF+LPS +  DPLR  +F+PL+I CL++  +             D LF+ F  E    R+ LLQE I  RFGFI++    YS+      ++ K                           YIH +G +F  +P YSK              +  + N +SS T+++  +E         IG+ W++N MLT+ W    TG    DE+F DR+L DF +FC N DNRL  F+
Sbjct: 1048 FISAEAVHWLVNNISWVQSQVMAMDIMQKMLEEQYITHASGETFRTFIYGFYLYKI-----------------------------PADKEPD---RASNLVQPCVWHSTAMEDFTAFQRKWFEVALVEEELLHSEIPP-------FLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSSYYHGNFSLTAAFEIKLHWMAATAAMLFEMVQGWHRKAPSCGFLLVPVVEGPFSLPSYLYGDPLRAQLFIPLNISCLVKAEN-------------DHLFEGFEPETYWERMYLLQEVIAYRFGFIQD---KYSASAFNFPSENKP-------------------------QYIHVTGTVFLQLP-YSKR----------KGQQRRRRNSTSSSTQNLFGEE--------RIGYNWAYNTMLTKTWRSIGTG----DERFADRLLKDFTDFCANRDNRLGTFW 1432

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000047660.1 (DEP domain containing 5 [Source:NCBI gene;Acc:100498286])

HSP 1 Score: 333.183 bits (853), Expect = 2.054e-92
Identity = 222/661 (33.59%), Postives = 348/661 (52.65%), Query Frame = 3

Query:   96 EDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKI--DENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSS---SNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNF------------IYEIP-----ENSLNF--VR--KLSKPEIVSDNISGVISTSNNCERGGLYHGSYGSHNSKDDTFINPIKPGHK-----------------RIIQSDHRKALFNPFAPNRFNV-------------------------------RTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFE-KKNSKNMAEAWKNYYKLYTEANNK 1844
            +D+++   K F +I+ G ++EI    ND++   L+++ ++  +  QK+T+S D  +    +L P + +   V++   +TLD++++  +DQY+ R DM+R     +  VL  +    F    R  V E+W   ++   GY   +TRVVFRS +++V+IFIQMS+E+W+FD +G+LYF+KA+N F++DLF KW++ NC H++T+VLFSR FY   N E+  +   RN  +  D  GRFYEDFY VVVQNER    EW  ++ T+K  F  Y   +       F    N     S+++  N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR+   +TKQR+ D G+G+DLVC+GEQPLHAVPLF    +SS   S + D+ Y IP+WINHSFY S  + Q +    F PRIK++  K  ++  L   + +N              ++ +P     + S+ F  VR  ++ K     D     +S     E G   +    S     +  + P    H+                 R+I+S  R +     AP RF+V                               + TSN RRW H FP+  + + IQ+HHQ   N  +L G   ++ S + AE  +  Y   T +N++
Sbjct:   19 DDELVINPKVFPYINLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETVSIDQTVAQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLK---KIPVLSQTCYWLFL-ICRAQVGELWVKSEKVTCGYISEDTRVVFRSTSAMVYIFIQMSSELWDFDIYGDLYFEKAVNGFLADLFNKWKDKNCSHEVTVVLFSRTFYDAKNIEDFPE-AHRNASVMQDHKGRFYEDFYKVVVQNERR--EEWTSLLVTIKKLFIQYPVLVRLENAEGFPPGHN-----STSDQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFQVDRSLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSSPGDSRLGDD-YNIPHWINHSFYTS--QSQPLN-NSFTPRIKLAPRK--VLASLYPKETENALPIQVDYDAYDSQVFRLPGPSRAQRSITFRAVRETQVRKSSCSYDTSCSPVSRPFTAEEGRSQNSDESSLGKLSNILLIPRPHLHQYEASSSLGYTSTRDFLERMIESQQRDSS----APGRFHVGSAESMLHVRPGGYHPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGMREASHSSAELLELAYHEATGSNHR 655

HSP 2 Score: 141.354 bits (355), Expect = 7.919e-33
Identity = 93/271 (34.32%), Postives = 137/271 (50.55%), Query Frame = 3

Query: 2196 IGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNP--PALNYSSTIFXXXXXXXXXXXXXXXXA----IYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSK-DFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQN--SLIEEFFKFLEGIN 2981
            +GVDWKSLT PA LP+T+DY+P  + L++++ E  Y L+  +     +         +    VF+E I QRL QG+Q+I  P  P    S               +    A     Y   +GR FH + +K  +I VT+Y P++    A I+Y Y L    S+ DF+ S  +FS + LE + WNY D YI + G      ++D   + LI SLKFWR+RF LLP+              + RCDIY ++   EQ    L++ F +F+EG+N
Sbjct:  687 VGVDWKSLTTPACLPLTTDYFPDRQSLQNDYTEGCYDLLPEADLDRRDEEGAQ----MTAQQVFEEFICQRLMQGYQIIVQPKHPKAISSVPPPLSSSPLYRRGLVSRNRAEEENQYWLSMGRTFHKVTLKDKIITVTRYLPKYPYESAQISYMYSLCPSHSECDFVSSWVEFSHERLEDYKWNYLDQYICSAG------SED---FSLIESLKFWRTRFLLLPSCVG---PTKRITEGEQRCDIYGERPRSEQEEAQLLDGFLRFVEGLN 941

HSP 3 Score: 129.798 bits (325), Expect = 2.605e-29
Identity = 133/488 (27.25%), Postives = 202/488 (41.39%), Query Frame = 3

Query: 3645 FTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNIXXXXXXXXXXXXXXXDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ--LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKW---TTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            F S EAVHW ++ +  +     A+  +QK++  +YI HAS  +   F+YGF  Y +                              A  E D   ++ N ++    +  +ME     +R + E + +   L     P        FL+  +P +       H +     G       L        + V LD++ +   +R EW    Y  N+  T AFE  + W+ AT   L E +  W +K       LVPV   PF+LPS +  DPLR  +F+PL+I CL++  +             D LF+ F  E    R+ LLQE I  RFGFI++    YS+      ++ K                           YIH +G +F  +P YSK              +  + N +SS T+++  +E         IG+ W++N MLT+ W    TG    DE+F DR+L DF +FC N DNRL  F+
Sbjct: 1092 FISAEAVHWLVNNISWVQSQVMAMDIMQKMLEEQYITHASGETFRTFIYGFYLYKI-----------------------------PADKEPD---RASNLVQPCVWHSTAMEDFTAFQRKWFEVALVEEELLHSEIPP-------FLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSSYYHGNFSLTAAFEIKLHWMAATAAMLFEMVQGWHRKAPSCGFLLVPVVEGPFSLPSYLYGDPLRAQLFIPLNISCLVKAEN-------------DHLFEGFEPETYWERMYLLQEVIAYRFGFIQD---KYSASAFNFPSENKP-------------------------QYIHVTGTVFLQLP-YSKR----------KGQQRRRRNSTSSSTQNLFGEE--------RIGYNWAYNTMLTKTWRSIGTG----DERFADRLLKDFTDFCANRDNRLGTFW 1476

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000047706.1 (DEP domain containing 5 [Source:NCBI gene;Acc:100498286])

HSP 1 Score: 332.028 bits (850), Expect = 5.135e-92
Identity = 216/634 (34.07%), Postives = 335/634 (52.84%), Query Frame = 3

Query:   96 EDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKI--DENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSS---SNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNF------------IYEIP-----ENSLNF--VR--KLSKPEIVSDNISGVISTSNNCERGGLYHGSYGSHNSKDDTFINPIKPGHK-----------------RIIQSDHRKALFNPFAPNRFNV-------------------------------RTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYG 1766
            +D+++   K F +I+ G ++EI    ND++   L+++ ++  +  QK+T+S D  +    +L P + +   V++   +TLD++++  +DQY+ R DM+R     +  VL  +    F    R  V E+W   ++   GY   +TRVVFRS +++V+IFIQMS+E+W+FD +G+LYF+KA+N F++DLF KW++ NC H++T+VLFSR FY   N E+  +   RN  +  D  GRFYEDFY VVVQNER    EW  ++ T+K  F  Y   +       F    N     S+++  N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR+   +TKQR+ D G+G+DLVC+GEQPLHAVPLF    +SS   S + D+ Y IP+WINHSFY S  + Q +    F PRIK++  K  ++  L   + +N              ++ +P     + S+ F  VR  ++ K     D     +S     E G   +    S     +  + P    H+                 R+I+S  R +     AP RF+V                               + TSN RRW H FP+  + + IQ+HHQ   N  +L G
Sbjct:   19 DDELVINPKVFPYINLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETVSIDQTVAQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLK---KIPVLSQTCYWLFL-ICRAQVGELWVKSEKVTCGYISEDTRVVFRSTSAMVYIFIQMSSELWDFDIYGDLYFEKAVNGFLADLFNKWKDKNCSHEVTVVLFSRTFYDAKNIEDFPE-AHRNASVMQDHKGRFYEDFYKVVVQNERR--EEWTSLLVTIKKLFIQYPVLVRLENAEGFPPGHN-----STSDQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFQVDRSLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSSPGDSRLGDD-YNIPHWINHSFYTS--QSQPLN-NSFTPRIKLAPRK--VLASLYPKETENALPIQVDYDAYDSQVFRLPGPSRAQRSITFRAVRETQVRKSSCSYDTSCSPVSRPFTAEEGRSQNSDESSLGKLSNILLIPRPHLHQYEASSSLGYTSTRDFLERMIESQQRDS----SAPGRFHVGSAESMLHVRPGGYHPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQG 628

HSP 2 Score: 141.739 bits (356), Expect = 5.541e-33
Identity = 93/271 (34.32%), Postives = 137/271 (50.55%), Query Frame = 3

Query: 2196 IGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNP--PALNYSSTIFXXXXXXXXXXXXXXXXA----IYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSK-DFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQN--SLIEEFFKFLEGIN 2981
            +GVDWKSLT PA LP+T+DY+P  + L++++ E  Y L+  +     +         +    VF+E I QRL QG+Q+I  P  P    S               +    A     Y   +GR FH + +K  +I VT+Y P++    A I+Y Y L    S+ DF+ S  +FS + LE + WNY D YI + G      ++D   + LI SLKFWR+RF LLP+              + RCDIY ++   EQ    L++ F +F+EG+N
Sbjct:  706 VGVDWKSLTTPACLPLTTDYFPDRQSLQNDYTEGCYDLLPEADLDRRDEEGAQ----MTAQQVFEEFICQRLMQGYQIIVQPKHPKAISSVPPPLSSSPLYRRGLVSRNRAEEENQYWLSMGRTFHKVTLKDKIITVTRYLPKYPYESAQISYMYSLCPSHSECDFVSSWVEFSHERLEDYKWNYLDQYICSAG------SED---FSLIESLKFWRTRFLLLPSCVG---PTKRITEGEQRCDIYGERPRSEQEEAQLLDGFLRFVEGLN 960

HSP 3 Score: 135.961 bits (341), Expect = 3.305e-31
Identity = 139/522 (26.63%), Postives = 214/522 (41.00%), Query Frame = 3

Query: 3543 LSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNIXXXXXXXXXXXXXXXDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ--LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKW---TTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            L  ++    +LE M +   G+  L   +      F S EAVHW ++ +  +     A+  +QK++  +YI HAS  +   F+YGF  Y +                              A  E D   ++ N ++    +  +ME     +R + E + +   L     P        FL+  +P +       H +     G       L        + V LD++ +   +R EW    Y  N+  T AFE  + W+ AT   L E +  W +K       LVPV   PF+LPS +  DPLR  +F+PL+I CL++  +             D LF+ F  E    R+ LLQE I  RFGFI++    YS+      ++ K                           YIH +G +F  +P YSK              +  + N +SS T+++  +E         IG+ W++N MLT+ W    TG    DE+F DR+L DF +FC N DNRL  F+
Sbjct: 1055 LPTTASLSEILEAMKHPTTGIPLLSEQKCLPPGCFISAEAVHWLVNNISWVQSQVMAMDIMQKMLEEQYITHASGETFRTFIYGFYLYKI-----------------------------PADKEPD---RASNLVQPCVWHSTAMEDFTAFQRKWFEVALVEEELLHSEIPP-------FLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSSYYHGNFSLTAAFEIKLHWMAATAAMLFEMVQGWHRKAPSCGFLLVPVVEGPFSLPSYLYGDPLRAQLFIPLNISCLVKAEN-------------DHLFEGFEPETYWERMYLLQEVIAYRFGFIQD---KYSASAFNFPSENKP-------------------------QYIHVTGTVFLQLP-YSKR----------KGQQRRRRNSTSSSTQNLFGEE--------RIGYNWAYNTMLTKTWRSIGTG----DERFADRLLKDFTDFCANRDNRLGTFW 1473

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000047348.1 (DEP domain containing 5 [Source:NCBI gene;Acc:100498286])

HSP 1 Score: 331.643 bits (849), Expect = 6.883e-92
Identity = 217/642 (33.80%), Postives = 337/642 (52.49%), Query Frame = 3

Query:   96 EDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKI--DENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSS---SNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIE-------KLAKPKDDNNF-------------IYEIP-----ENSLNF--VR--KLSKPEIVSDNISGVISTSNNCERGGLYHGSYGSHNSKDDTFINPIKPGHK-----------------RIIQSDHRKALFNPFAPNRFNV-------------------------------RTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYG 1766
            +D+++   K F +I+ G ++EI    ND++   L+++ ++  +  QK+T+S D  +    +L P + +   V++   +TLD++++  +DQY+ R DM+R     +  VL  +    F    R  V E+W   ++   GY   +TRVVFRS +++V+IFIQMS+E+W+FD +G+LYF+KA+N F++DLF KW++ NC H++T+VLFSR FY   N E+  +   RN  +  D  GRFYEDFY VVVQNER    EW  ++ T+K  F  Y   +       F    N     S+++  N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR+   +TKQR+ D G+G+DLVC+GEQPLHAVPLF    +SS   S + D+ Y IP+WINHSFY S  + Q +    F PRIK++  K++  +        +  PK+  N              ++ +P     + S+ F  VR  ++ K     D     +S     E G   +    S     +  + P    H+                 R+I+S  R +     AP RF+V                               + TSN RRW H FP+  + + IQ+HHQ   N  +L G
Sbjct:   19 DDELVINPKVFPYINLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETVSIDQTVAQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLK---KIPVLSQTCYWLFL-ICRAQVGELWVKSEKVTCGYISEDTRVVFRSTSAMVYIFIQMSSELWDFDIYGDLYFEKAVNGFLADLFNKWKDKNCSHEVTVVLFSRTFYDAKNIEDFPE-AHRNASVMQDHKGRFYEDFYKVVVQNERR--EEWTSLLVTIKKLFIQYPVLVRLENAEGFPPGHN-----STSDQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFQVDRSLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSSPGDSRLGDD-YNIPHWINHSFYTS--QSQPLN-NSFTPRIKLAPRKTNSEKGRTGKDPSIGSPKETENALPIQVDYDAYDSQVFRLPGPSRAQRSITFRAVRETQVRKSSCSYDTSCSPVSRPFTAEEGRSQNSDESSLGKLSNILLIPRPHLHQYEASSSLGYTSTRDFLERMIESQQRDS----SAPGRFHVGSAESMLHVRPGGYHPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQG 638

HSP 2 Score: 141.739 bits (356), Expect = 4.991e-33
Identity = 93/271 (34.32%), Postives = 137/271 (50.55%), Query Frame = 3

Query: 2196 IGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNP--PALNYSSTIFXXXXXXXXXXXXXXXXA----IYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSK-DFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQN--SLIEEFFKFLEGIN 2981
            +GVDWKSLT PA LP+T+DY+P  + L++++ E  Y L+  +     +         +    VF+E I QRL QG+Q+I  P  P    S               +    A     Y   +GR FH + +K  +I VT+Y P++    A I+Y Y L    S+ DF+ S  +FS + LE + WNY D YI + G      ++D   + LI SLKFWR+RF LLP+              + RCDIY ++   EQ    L++ F +F+EG+N
Sbjct:  716 VGVDWKSLTTPACLPLTTDYFPDRQSLQNDYTEGCYDLLPEADLDRRDEEGAQ----MTAQQVFEEFICQRLMQGYQIIVQPKHPKAISSVPPPLSSSPLYRRGLVSRNRAEEENQYWLSMGRTFHKVTLKDKIITVTRYLPKYPYESAQISYMYSLCPSHSECDFVSSWVEFSHERLEDYKWNYLDQYICSAG------SED---FSLIESLKFWRTRFLLLPSCVG---PTKRITEGEQRCDIYGERPRSEQEEAQLLDGFLRFVEGLN 970

HSP 3 Score: 130.568 bits (327), Expect = 1.471e-29
Identity = 133/488 (27.25%), Postives = 202/488 (41.39%), Query Frame = 3

Query: 3645 FTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNIXXXXXXXXXXXXXXXDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ--LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKW---TTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            F S EAVHW ++ +  +     A+  +QK++  +YI HAS  +   F+YGF  Y +                              A  E D   ++ N ++    +  +ME     +R + E + +   L     P        FL+  +P +       H +     G       L        + V LD++ +   +R EW    Y  N+  T AFE  + W+ AT   L E +  W +K       LVPV   PF+LPS +  DPLR  +F+PL+I CL++  +             D LF+ F  E    R+ LLQE I  RFGFI++    YS+      ++ K                           YIH +G +F  +P YSK              +  + N +SS T+++  +E         IG+ W++N MLT+ W    TG    DE+F DR+L DF +FC N DNRL  F+
Sbjct: 1100 FISAEAVHWLVNNISWVQSQVMAMDIMQKMLEEQYITHASGETFRTFIYGFYLYKI-----------------------------PADKEPD---RASNLVQPCVWHSTAMEDFTAFQRKWFEVALVEEELLHSEIPP-------FLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSSYYHGNFSLTAAFEIKLHWMAATAAMLFEMVQGWHRKAPSCGFLLVPVVEGPFSLPSYLYGDPLRAQLFIPLNISCLVKAEN-------------DHLFEGFEPETYWERMYLLQEVIAYRFGFIQD---KYSASAFNFPSENKP-------------------------QYIHVTGTVFLQLP-YSKR----------KGQQRRRRNSTSSSTQNLFGEE--------RIGYNWAYNTMLTKTWRSIGTG----DERFADRLLKDFTDFCANRDNRLGTFW 1484

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Mouse
Match: Depdc5 (DEP domain containing 5 [Source:MGI Symbol;Acc:MGI:2141101])

HSP 1 Score: 338.961 bits (868), Expect = 2.342e-96
Identity = 185/461 (40.13%), Postives = 285/461 (61.82%), Query Frame = 3

Query:   66 RLVFHKKL--KPEDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKS---SSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFIYEIPENSL 1424
            +LV HKK     +D+++   K F  I  G ++EI    ND++   L+++ ++  +  QK+TIS D  +    +L P + +   V++   +TLD++++  +DQY+ R DM+R    + ++   +++K++F G  R    E+W   ++   GY    TRVVFRS +++V+IFIQMS EMW+FD +G+LYF+KA+N F++DLF KW+  NC H++T+VLFSR FY   + +   +  + +I+ D  GRFYEDFY VVVQNER    EW  ++ T+K  F  Y   +   Q   F    N     S++   N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR    +TKQR+ D G+G+DLVC+GEQPLHAVPLF    +S    S + D+ Y IP+WINHSFY S ++L       F PRIK++ +KS+  EK    +D +    +  EN+L
Sbjct:    8 KLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAG-IRAQAGELWVKNEKVMCGYISEETRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSIDEFPEINRASIQEDHKGRFYEDFYKVVVQNERR--EEWTSLLVTIKKLFIQYPVLVRLEQAGGFPQGDN-----STSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSVPRDSRLGDD-YNIPHWINHSFYTSKSQLFC---NSFTPRIKLAGKKSA-SEKTKNGRDTSLGTPKESENTL 453

HSP 2 Score: 150.599 bits (379), Expect = 6.350e-36
Identity = 108/336 (32.14%), Postives = 165/336 (49.11%), Query Frame = 3

Query: 2196 IGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMI----------TNPPALNYSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNY--CLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQN--SLIEEFFKFLEGINK----------IKRRSPNSKPKMSMPVIDNSSNLMNNPSMVKVKSVSGNLLEMKVSSSNM 3131
            +GVDWKSLT PA LP+T+DY+P  + L++++ E  Y L+  +     +         +    VF+E I QRL QG+Q+I          T PP L+ SS ++        S    ++   Y   +GR FH + +K  +I VT+Y P++    A I Y Y  C    DS +F+     F  + LE++ WNY D YI + G     S D    + LI SLKFWR+RF LLP   A  T        ++ CDIY DK   +++   L++ F +F+EG+N+          I++ +     +M+ P+  +S      P   K  S    LLEM+ S  ++
Sbjct:  730 VGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADMDRRDEEGVQ----MTAQQVFEEFICQRLMQGYQIIVQPKTQKPNTTVPPPLS-SSPLY---SRGLVSRNRPEEEGQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDS-EFVSCWVDFCHERLEEYKWNYLDQYICSAG-----SED----FSLIESLKFWRTRFLLLP---ACVTATKRITEGEVHCDIYGDKPRADEDEWQLLDGFIRFVEGLNRIRRRHRSDRMIRKGTAMKGLQMTGPISAHSLEAAGPPVGKKGTSALSALLEMEASQKSL 1044

HSP 3 Score: 63.1586 bits (152), Expect = 4.000e-9
Identity = 25/57 (43.86%), Postives = 38/57 (66.67%), Query Frame = 3

Query: 1611 RKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKN 1781
            ++AL NPFAP+R  ++ TSN RRW H FP+  + + IQ+HHQ   N  +L G  +++
Sbjct:  594 QRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSRQRD 650

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Mouse
Match: Depdc5 (DEP domain containing 5 [Source:MGI Symbol;Acc:MGI:2141101])

HSP 1 Score: 338.961 bits (868), Expect = 2.788e-94
Identity = 185/461 (40.13%), Postives = 285/461 (61.82%), Query Frame = 3

Query:   66 RLVFHKKL--KPEDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKS---SSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFIYEIPENSL 1424
            +LV HKK     +D+++   K F  I  G ++EI    ND++   L+++ ++  +  QK+TIS D  +    +L P + +   V++   +TLD++++  +DQY+ R DM+R    + ++   +++K++F G  R    E+W   ++   GY    TRVVFRS +++V+IFIQMS EMW+FD +G+LYF+KA+N F++DLF KW+  NC H++T+VLFSR FY   + +   +  + +I+ D  GRFYEDFY VVVQNER    EW  ++ T+K  F  Y   +   Q   F    N     S++   N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR    +TKQR+ D G+G+DLVC+GEQPLHAVPLF    +S    S + D+ Y IP+WINHSFY S ++L       F PRIK++ +KS+  EK    +D +    +  EN+L
Sbjct:    8 KLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAG-IRAQAGELWVKNEKVMCGYISEETRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSIDEFPEINRASIQEDHKGRFYEDFYKVVVQNERR--EEWTSLLVTIKKLFIQYPVLVRLEQAGGFPQGDN-----STSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSVPRDSRLGDD-YNIPHWINHSFYTSKSQLFC---NSFTPRIKLAGKKSA-SEKTKNGRDTSLGTPKESENTL 453

HSP 2 Score: 209.534 bits (532), Expect = 7.841e-54
Identity = 203/790 (25.70%), Postives = 328/790 (41.52%), Query Frame = 3

Query: 2196 IGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNPPALNYSSTIFXXXXXX------XXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNY--CLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQN--SLIEEFFKFLEGINK----------IKRRSPNSKPKMSMPVIDNSSNLMNNPSMVKVKSVSGNLLEMKVSSSNMXXXXXXXXXXXXXXXXDKIDLLMLIQSYLIACEPSINSTLDNLVNVPSSGGSLNQHQKSAIQSACIVTNANPMSPSRPAVHHRHSTTHEPNHYNQLCELISNNSSNPVTPIEKYPRQFTFDSLENTMKSSSGLELDKLSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNIXXXXXXXXXXXXXXXDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ--LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENA 4496
            +GVDWKSLT PA LP+T+DY+P  + L++++ E  Y L+  +     +         +    VF+E I QRL QG+Q+I  P     ++T+     +         S    ++   Y   +GR FH + +K  +I VT+Y P++    A I Y Y  C    DS +F+     F  + LE++ WNY D YI + G      ++D   + LI SLKFWR+RF LLP   A  T        ++ CDIY DK   +++   L++ F +F+EG+N+          I++ +     +M+ P+  +S      P   K  S    LLEM+ S  ++      +         +   + M   +Y+ +      +     V  P +  S    Q S  Q+A +V ++  +  S      R +        NQ       NS N    IE+      F S  +   SS       L+ SS  V +LE M +   G+  L   +  +   F S E VHW ++ ++ +      +  +QK++  + I HAS  +   F+YGF FY +                                 E +     + +  W   Y    +     +R + E +F+   L     P        FL+  +P +       H +     G       L        + V LD++ +   +R EW    Y  N+    AFE  + W+  T   L E +  W +K +     LVPV   PFALPS +  DPLR  +F+PL++ CL++  
Sbjct:  739 VGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADMDRRDEEGVQ----MTAQQVFEEFICQRLMQGYQIIVQPKTQKPNTTVPPPLSSSPLYSRGLVSRNRPEEEGQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDS-EFVSCWVDFCHERLEEYKWNYLDQYICSAG------SED---FSLIESLKFWRTRFLLLP---ACVTATKRITEGEVHCDIYGDKPRADEDEWQLLDGFIRFVEGLNRIRRRHRSDRMIRKGTAMKGLQMTGPISAHSLEAAGPPVGKKGTSALSALLEMEASQKSLGEQQTTVHGKSSTQPAENSSVAM-TPTYVDSPRKD-GAFFMEFVRSPRTASSAFYPQASVDQTAPLVLDSTSLGVSTGQPMDRGN--------NQ----TFGNSQN----IEQ-----AFPSANSGDYSSQQHVASSLTSSSTLVEILEAMKHPSTGVQLLSEQKGLSPCCFISAEVVHWLMNNVEGVQTQAMGIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIV-----------------------------MDKEPERVAMQQPSAPW---YTAGADDFASFQRKWFEVAFVAEELVHSEIPA-------FLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTATVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNLSCLLKEG 1449

HSP 3 Score: 63.1586 bits (152), Expect = 3.685e-9
Identity = 25/57 (43.86%), Postives = 38/57 (66.67%), Query Frame = 3

Query: 1611 RKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKN 1781
            ++AL NPFAP+R  ++ TSN RRW H FP+  + + IQ+HHQ   N  +L G  +++
Sbjct:  594 QRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSRQRD 650

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Mouse
Match: Depdc5 (DEP domain containing 5 [Source:MGI Symbol;Acc:MGI:2141101])

HSP 1 Score: 337.421 bits (864), Expect = 1.161e-93
Identity = 185/461 (40.13%), Postives = 285/461 (61.82%), Query Frame = 3

Query:   66 RLVFHKKL--KPEDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKS---SSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFIYEIPENSL 1424
            +LV HKK     +D+++   K F  I  G ++EI    ND++   L+++ ++  +  QK+TIS D  +    +L P + +   V++   +TLD++++  +DQY+ R DM+R    + ++   +++K++F G  R    E+W   ++   GY    TRVVFRS +++V+IFIQMS EMW+FD +G+LYF+KA+N F++DLF KW+  NC H++T+VLFSR FY   + +   +  + +I+ D  GRFYEDFY VVVQNER    EW  ++ T+K  F  Y   +   Q   F    N     S++   N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR    +TKQR+ D G+G+DLVC+GEQPLHAVPLF    +S    S + D+ Y IP+WINHSFY S ++L       F PRIK++ +KS+  EK    +D +    +  EN+L
Sbjct:    8 KLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAG-IRAQAGELWVKNEKVMCGYISEETRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSIDEFPEINRASIQEDHKGRFYEDFYKVVVQNERR--EEWTSLLVTIKKLFIQYPVLVRLEQAGGFPQGDN-----STSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSVPRDSRLGDD-YNIPHWINHSFYTSKSQLFC---NSFTPRIKLAGKKSA-SEKTKNGRDTSLGTPKESENTL 453

HSP 2 Score: 149.058 bits (375), Expect = 2.963e-35
Identity = 103/332 (31.02%), Postives = 163/332 (49.10%), Query Frame = 3

Query: 2196 IGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNPPALNYSSTIFXXXXXX------XXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNY--CLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQN--SLIEEFFKFLEGINK----------IKRRSPNSKPKMSMPVIDNSSNLMNNPSMVKVKSVSGNLLEMKVSSSNM 3131
            +GVDWKSLT PA LP+T+DY+P  + L++++ E  Y L+  +     +         +    VF+E I QRL QG+Q+I  P     ++T+     +         S    ++   Y   +GR FH + +K  +I VT+Y P++    A I Y Y  C    DS +F+     F  + LE++ WNY D YI + G      ++D   + LI SLKFWR+RF LLP   A  T        ++ CDIY DK   +++   L++ F +F+EG+N+          I++ +     +M+ P+  +S      P   K  S    LLEM+ S  ++
Sbjct:  730 VGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADMDRRDEEGVQ----MTAQQVFEEFICQRLMQGYQIIVQPKTQKPNTTVPPPLSSSPLYSRGLVSRNRPEEEGQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDS-EFVSCWVDFCHERLEEYKWNYLDQYICSAG------SED---FSLIESLKFWRTRFLLLP---ACVTATKRITEGEVHCDIYGDKPRADEDEWQLLDGFIRFVEGLNRIRRRHRSDRMIRKGTAMKGLQMTGPISAHSLEAAGPPVGKKGTSALSALLEMEASQKSL 1044

HSP 3 Score: 145.206 bits (365), Expect = 3.597e-34
Identity = 131/512 (25.59%), Postives = 206/512 (40.23%), Query Frame = 3

Query: 3564 VRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNIXXXXXXXXXXXXXXXDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ--LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            V +LE M +   G+  L   +  +   F S E VHW ++ ++ +      +  +QK++  + I HAS  +   F+YGF FY +                                 E +     + +  W   Y    +     +R + E +F+   L     P        FL+  +P +       H +     G       L        + V LD++ +   +R EW    Y  N+    AFE  + W+  T   L E +  W +K +     LVPV   PFALPS +  DPLR  +F+PL++ CL++      S H         LFD F  E    R+ L QEAI  RFGF+++    YS      N   +N  +                       YIH +G +F  +P YSK +            +  + N +SS  +++  +E         +G+ W++N MLT+ W +     DE+F DR+L DF +FC N DNRL  F+
Sbjct: 1144 VEILEAMKHPSTGVQLLSEQKGLSPCCFISAEVVHWLMNNVEGVQTQAMGIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIV-----------------------------MDKEPERVAMQQPSAPW---YTAGADDFASFQRKWFEVAFVAEELVHSEIPA-------FLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTATVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNLSCLLKEG----SEH---------LFDSFEPETYWDRMHLFQEAIAHRFGFVQD---KYSVS--AFNFPAENKPQ-----------------------YIHVTGTVFLQLP-YSKRKFSGQ--------QRRRRNSTSSTNQNMFCEE--------RVGYNWAYNTMLTKTWRSS-ATGDEKFADRLLKDFTDFCINRDNRLVTFW 1557

HSP 4 Score: 63.1586 bits (152), Expect = 4.311e-9
Identity = 25/57 (43.86%), Postives = 38/57 (66.67%), Query Frame = 3

Query: 1611 RKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKN 1781
            ++AL NPFAP+R  ++ TSN RRW H FP+  + + IQ+HHQ   N  +L G  +++
Sbjct:  594 QRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSRQRD 650

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Mouse
Match: Depdc5 (DEP domain containing 5 [Source:MGI Symbol;Acc:MGI:2141101])

HSP 1 Score: 337.421 bits (864), Expect = 1.224e-93
Identity = 185/461 (40.13%), Postives = 285/461 (61.82%), Query Frame = 3

Query:   66 RLVFHKKL--KPEDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKS---SSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFIYEIPENSL 1424
            +LV HKK     +D+++   K F  I  G ++EI    ND++   L+++ ++  +  QK+TIS D  +    +L P + +   V++   +TLD++++  +DQY+ R DM+R    + ++   +++K++F G  R    E+W   ++   GY    TRVVFRS +++V+IFIQMS EMW+FD +G+LYF+KA+N F++DLF KW+  NC H++T+VLFSR FY   + +   +  + +I+ D  GRFYEDFY VVVQNER    EW  ++ T+K  F  Y   +   Q   F    N     S++   N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR    +TKQR+ D G+G+DLVC+GEQPLHAVPLF    +S    S + D+ Y IP+WINHSFY S ++L       F PRIK++ +KS+  EK    +D +    +  EN+L
Sbjct:    8 KLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAG-IRAQAGELWVKNEKVMCGYISEETRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSIDEFPEINRASIQEDHKGRFYEDFYKVVVQNERR--EEWTSLLVTIKKLFIQYPVLVRLEQAGGFPQGDN-----STSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSVPRDSRLGDD-YNIPHWINHSFYTSKSQLFC---NSFTPRIKLAGKKSA-SEKTKNGRDTSLGTPKESENTL 453

HSP 2 Score: 268.47 bits (685), Expect = 5.056e-72
Identity = 260/988 (26.32%), Postives = 412/988 (41.70%), Query Frame = 3

Query: 2196 IGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNPPALNYSSTIFXXXXXX------XXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNY--CLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQN--SLIEEFFKFLEGINK----------IKRRSPNSKPKMSMPVIDNSSNLMNNPSMVKVKSVSGNLLEMKVSSSNMXXXXXXXXXXXXXXXXDKIDLLMLIQSYLIACEPSINSTLDNLVNVPSSGGSLNQHQKSAIQSACIVTNANPMSPSRPAVHHRHSTTHEPNHYNQLCELISNNSSNPVTPIEKYPRQFTFDSLENTMKSSSGLELDKLSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNIXXXXXXXXXXXXXXXDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ--LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            +GVDWKSLT PA LP+T+DY+P  + L++++ E  Y L+  +     +         +    VF+E I QRL QG+Q+I  P     ++T+     +         S    ++   Y   +GR FH + +K  +I VT+Y P++    A I Y Y  C    DS +F+     F  + LE++ WNY D YI + G      ++D   + LI SLKFWR+RF LLP   A  T        ++ CDIY DK   +++   L++ F +F+EG+N+          I++ +     +M+ P+  +S      P   K  S    LLEM+ S  ++      +         +   + M   +Y+ +      +     V  P +  S    Q S  Q+A +V ++  +  S      R +        NQ       NS N    IE+      F S  +   SS       L+ SS  V +LE M +   G+  L   +  +   F S E VHW ++ ++ +      +  +QK++  + I HAS  +   F+YGF FY +                                 E +     + +  W   Y    +     +R + E +F+   L     P        FL+  +P +       H +     G       L        + V LD++ +   +R EW    Y  N+    AFE  + W+  T   L E +  W +K +     LVPV   PFALPS +  DPLR  +F+PL++ CL++      S H         LFD F  E    R+ L QEAI  RFGF+++    YS      N   +N  +                       YIH +G +F  +P YSK +            +  + N +SS  +++  +E         +G+ W++N MLT+ W +     DE+F DR+L DF +FC N DNRL  F+
Sbjct:  730 VGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADMDRRDEEGVQ----MTAQQVFEEFICQRLMQGYQIIVQPKTQKPNTTVPPPLSSSPLYSRGLVSRNRPEEEGQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDS-EFVSCWVDFCHERLEEYKWNYLDQYICSAG------SED---FSLIESLKFWRTRFLLLP---ACVTATKRITEGEVHCDIYGDKPRADEDEWQLLDGFIRFVEGLNRIRRRHRSDRMIRKGTAMKGLQMTGPISAHSLEAAGPPVGKKGTSALSALLEMEASQKSLGEQQTTVHGKSSTQPAENSSVAM-TPTYVDSPRKD-GAFFMEFVRSPRTASSAFYPQASVDQTAPLVLDSTSLGVSTGQPMDRGN--------NQ----TFGNSQN----IEQ-----AFPSANSGDYSSQQHVASSLTSSSTLVEILEAMKHPSTGVQLLSEQKGLSPCCFISAEVVHWLMNNVEGVQTQAMGIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIV-----------------------------MDKEPERVAMQQPSAPW---YTAGADDFASFQRKWFEVAFVAEELVHSEIPA-------FLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTATVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNLSCLLKEG----SEH---------LFDSFEPETYWDRMHLFQEAIAHRFGFVQD---KYSVS--AFNFPAENKPQ-----------------------YIHVTGTVFLQLP-YSKRKFSGQ--------QRRRRNSTSSTNQNMFCEE--------RVGYNWAYNTMLTKTWRSS-ATGDEKFADRLLKDFTDFCINRDNRLVTFW 1579

HSP 3 Score: 62.7734 bits (151), Expect = 4.663e-9
Identity = 25/57 (43.86%), Postives = 38/57 (66.67%), Query Frame = 3

Query: 1611 RKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKN 1781
            ++AL NPFAP+R  ++ TSN RRW H FP+  + + IQ+HHQ   N  +L G  +++
Sbjct:  594 QRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSRQRD 650

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Mouse
Match: Depdc5 (DEP domain containing 5 [Source:MGI Symbol;Acc:MGI:2141101])

HSP 1 Score: 150.214 bits (378), Expect = 1.134e-36
Identity = 144/536 (26.87%), Postives = 235/536 (43.84%), Query Frame = 3

Query: 2196 IGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNPPALNYSSTIFXXXXXX------XXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADI--TYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQN--SLIEEFFKFLEGINK----------IKRRSPNSKPKMSMPVIDNSSNLMNNPSMVKVKSVSGNLLEMKVSSSNMXXXXXXXXXXXXXXXXDKIDLLMLIQSYLIACEPSINST-LDNLVNVPSSGGSLNQHQKSAIQSACIVTNANPMSPSRPAVHHRHSTTHEPNHYNQLCELISNNSSNPVTPIEKYPRQFTFDSLENTMKSSSGLELDKLSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMN 3740
            +GVDWKSLT PA LP+T+DY+P  + L++++ E  Y L+  +     +         +    VF+E I QRL QG+Q+I  P     ++T+     +         S    ++   Y   +GR FH + +K  +I VT+Y P++    A I  TY+ C    DS +F+     F  + LE++ WNY D YI + G      ++D   + LI SLKFWR+RF LLP   A  T        ++ CDIY DK   +++   L++ F +F+EG+N+          I++ +     +M+ P+  +S      P   K  S    LLEM+ S  ++      +         +   + M   +Y+ +  P  +       V  P +  S    Q S  Q+A +V ++  +  S      R +        NQ       NS N    IE+      F S  +   SS       L+ SS  V +LE M +   G+  L   +  +   F S E VHW ++ ++ +      +  +Q L +
Sbjct:   92 VGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADMDRRDEEGVQ----MTAQQVFEEFICQRLMQGYQIIVQPKTQKPNTTVPPPLSSSPLYSRGLVSRNRPEEEGQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDS-EFVSCWVDFCHERLEEYKWNYLDQYICSAG------SED---FSLIESLKFWRTRFLLLP---ACVTATKRITEGEVHCDIYGDKPRADEDEWQLLDGFIRFVEGLNRIRRRHRSDRMIRKGTAMKGLQMTGPISAHSLEAAGPPVGKKGTSALSALLEMEASQKSLGEQQTTVHGKSSTQPAENSSVAM-TPTYVDS--PRKDGAFFMEFVRSPRTASSAFYPQASVDQTAPLVLDSTSLGVSTGQPMDRGN--------NQ----TFGNSQN----IEQ-----AFPSANSGDYSSQQHVASSLTSSSTLVEILEAMKHPSTGVQLLSEQKGLSPCCFISAEVVHWLMNNVEGVQTQAMGIDIMQWLCS 586

[Close]

BLAST of DEP domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9W0E3|IML1_DROME (GATOR complex protein Iml1 OS=Drosophila melanogaster OX=7227 GN=Iml1 PE=1 SV=2)

HSP 1 Score: 338.576 bits (867), Expect = 2.341e-93
Identity = 180/424 (42.45%), Postives = 272/424 (64.15%), Query Frame = 3

Query:  102 DILFTAKDFSFISKGSLLEIYQ--QENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGY-FRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYK-TELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSL 1358
            D++   KD    + G ++EIY   +EN  H L++I   N +   +D IS +S + N+ K+ P  ++  +++    + LD ++I  +DQY+ RS+M+R   ++ ++ + ++KK+D+     R  V EMW  G+R  SG    +T++VFRS+TS+V++F+QMS+EMW+FD  G+LYF+KA+N F+++LF KW+  +C H++TIVLFSR FY   + +   ++++  ++ D  GRFYEDFY V +QNER   ++W  V+  L+  F +Y+ T L   ++ N        S   SA   NFLE LNI+LN +E +Y+DR F+RTG++ VVIT G GV++VDR  T+ITKQRI D GVG DLVC+GEQPLHAVPL  F  K ++  + + Y +P+WIN SFY S N  + I    FIPRIK+    S L
Sbjct:   20 DLVMNLKDHPNANVGDVVEIYAPDEENGTHLLLQITEFNGS-CGRDVISIESGIANAFKMRPYSNVVMRIVKPADVALDSIEITFKDQYMGRSEMWRLKTYLTDTCVYVNKKIDYNDMQIRCQVYEMWSQGERVASGVITEDTKIVFRSSTSMVYLFLQMSSEMWDFDIHGDLYFEKAVNGFLTELFQKWRKLSCNHEVTIVLFSRTFYAAKSLDEFPEHMRDCLQQDYKGRFYEDFYRVAIQNER--CDDWCTVLGQLRKLFTSYQATVLRYHERENMKIPPATNS---SATQGNFLEVLNISLNTFEKHYLDRTFDRTGQLSVVITPGVGVFSVDRELTNITKQRIIDNGVGSDLVCVGEQPLHAVPLLKFHNKDTTLTSADDYSLPHWINLSFY-STN--KKIVYSSFIPRIKLPLFGSQL 434

HSP 2 Score: 161.384 bits (407), Expect = 2.908e-38
Identity = 93/268 (34.70%), Postives = 141/268 (52.61%), Query Frame = 3

Query: 2202 VDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMIT---NPPALNYSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRR 2996
            VDWKSLT+PA LPIT+DY+P  R L ++++ S+Y L+ +  N +   +   +RKPL   +V +E++ QRL QGFQ+I     PP  +  S+        +     ++ N  Y   +GRIFH I +   +I VT Y PRH     ++ Y Y    P  + + +S   F+T+ LE FNWN+ D YI   G            Y L+ SLK+WR R YLLP  +       +      RCDI+ D +       +E+F + +E ++K+KR+
Sbjct:  765 VDWKSLTIPACLPITTDYFPDKRSLNNDYVISDYTLLPDDVNHDYAQSRAVYRKPLSTEEVCKEIVSQRLAQGFQLIVVDEKPPTASGCSS----GSAVQPVKLSRETNKEYLLSIGRIFHKISLSGSVITVTGYRPRHPYPPINVDYRYRFHAPQHETYEISGVNFTTEKLENFNWNHMDLYICTRGD---------VDYPLMESLKYWRYRMYLLPRENI-----VSKIASCQRCDIFPDVTADNTREQVEDFVRLIEAVSKLKRQ 1014

HSP 3 Score: 134.806 bits (338), Expect = 3.657e-30
Identity = 98/307 (31.92%), Postives = 146/307 (47.56%), Query Frame = 3

Query: 4188 NGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ-LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKML-TRKW---TTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            N  +Y++  L+I+ ++  +R EWG  ++     P  AFE +V+W+ ++G  +A+ I  W +K +    LV VP DP A P +  SDPLRGPIF+PL    L   A                LFDEF +E R  R++  QEAIL +FGF+   C+                   +E K      L  +      + Y+H +G MFA+I   +     N  +  P+  E   +     +T + N  +         +GFLW+WN M+  +KW   T       E FQ +ML DFREFC+N+D RL  F+
Sbjct: 1266 NKRVYRQSHLEIDVNQKSDRMEWGHVKHHTVLQPRFAFEIVVEWVTSSGPIVADLIGGWMRKANQFNFLVSVPADPMAEPFTKKSDPLRGPIFIPLCTTFLPNGAA---------------LFDEFPEESRSDRMLFFQEAILGKFGFL--PCV-------------------LEKKYSVGKDLPKE------YQYVHCTGNMFALIRCATN----NYQVESPILKEANVTRCVYGHTNNTNVPK--------KVGFLWAWNHMIPNKKWKAQTINNSADGELFQLKMLKDFREFCSNSDQRLSTFW 1518

[Close]

BLAST of DEP domain-containing protein vs. UniProt/SwissProt
Match: sp|O75140|DEPD5_HUMAN (GATOR complex protein DEPDC5 OS=Homo sapiens OX=9606 GN=DEPDC5 PE=1 SV=2)

HSP 1 Score: 337.806 bits (865), Expect = 7.346e-93
Identity = 182/460 (39.57%), Postives = 283/460 (61.52%), Query Frame = 3

Query:   66 RLVFHKKL--KPEDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSS---SNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEK-------LAKPKDDNNFI 1400
            +LV HKK     +D+++   K F  I  G ++EI    ND++   L+++ ++  +  QK+TIS D  +    +L P + +   V++   +TLD++++  +DQY+ R DM+R    + ++   +++K++F G  R    E+W   ++   GY   +TRVVFRS +++V+IFIQMS EMW+FD +G+LYF+KA+N F++DLF KW+  NC H++T+VLFSR FY   + +   +  + +I+ D  GRFYEDFY VVVQNER    EW  ++ T+K  F  Y   +   Q   F    N     S++   N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR    +TKQR+ D G+G+DLVC+GEQPLHAVPLF    +S+   S + D+ Y IP+WINHSFY S ++L       F PRIK++ +K +  +        L  PK+  N +
Sbjct:    8 KLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAG-IRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRASIRQDHKGRFYEDFYKVVVQNERR--EEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDN-----STSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDD-YNIPHWINHSFYTSKSQLFC---NSFTPRIKLAGKKPASEKAKNGRDTSLGSPKESENAL 453

HSP 2 Score: 262.692 bits (670), Expect = 2.296e-69
Identity = 258/988 (26.11%), Postives = 412/988 (41.70%), Query Frame = 3

Query: 2196 IGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNP------PALNYSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNY--CLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQN--SLIEEFFKFLEGINK----------IKRRSPNSKPKMSMPVIDNSSNLMNNPSMVKVKSVSGNLLEMKVSSSNMXXXXXXXXXXXXXXXXDKIDLLMLIQSYLIACEPSINSTLDNLVNVPSSGGSLNQHQKSAIQSACIVTNANPMSPSRPAVHHRHSTTHEPNHYNQLCELISNNSSNPVTPIEKYPRQFTFDSLENTMKSSSGLELDKLSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNIXXXXXXXXXXXXXXXDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ--LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            +GVDWKSLT PA LP+T+DY+P  + L++++ E  Y L+  +     + +       +    VF+E I QRL QG+Q+I  P      PA+    +          S    ++   Y   +GR FH + +K  +I VT+Y P++    A I Y Y  C    DS +F+    +FS + LE++ WNY D YI + G      ++D   + LI SLKFWR+RF LLP   A  T        +  CDIY D+   +++   L++ F +F+EG+N+          +++ +     +M+ P+  +S      P   K  S    LLEM+ S   +      +      +   +   + +  +Y+ +      +     V  P +  S    Q S  Q+A  + +   +         R ++    N  N     I     +     +   +Q    SL ++   +  LE   +   S  V++L E    Q GL    SP     Y F S E VHW ++ ++ I     A+  +QK++  + I HAS  +   F+YGF FY +                                 E D     +    W   +   ++     +R + E +F+   L     P        FL+  +P +       H +     G       L        + V LD++ +   +R EW    Y  N+    AFE  + W+  T   L E +  W +K +     LVPV   PFALPS +  DPLR  +F+PL+I CL++      S H         LFD F  E    R+ L QEAI  RFGF+++    YS+     N   +N  +                       YIH +G +F  +P YSK +            +  + N +SS  +++  +E         +G+ W++N MLT+ W +     DE+F DR+L DF +FC N DNRL  F+
Sbjct:  740 VGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDEDGVQ----MTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDS-EFVSCWVEFSHERLEEYKWNYLDQYICSAG------SED---FSLIESLKFWRTRFLLLP---ACVTATKRITEGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKD-GAFFMEFVRSPRTASSAFYPQVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQN-----IGEQGYSSTNSSDSSSQQLVASSLTSSSTLTEILE--AMKHPSTGVQLLSE----QKGL----SP-----YCFISAEVVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVT-----------------------------DKEPDRVAMQQPATTW---HTAGVDDFASFQRKWFEVAFVAEELVHSEIPA-------FLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEG----SEH---------LFDSFEPETYWDRMHLFQEAIAHRFGFVQD---KYSAS--AFNFPAENKPQ-----------------------YIHVTGTVFLQLP-YSKRKFSGQ--------QRRRRNSTSSTNQNMFCEE--------RVGYNWAYNTMLTKTWRSS-ATGDEKFADRLLKDFTDFCINRDNRLVTFW 1591

HSP 3 Score: 62.3882 bits (150), Expect = 4.424e-8
Identity = 25/57 (43.86%), Postives = 38/57 (66.67%), Query Frame = 3

Query: 1611 RKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKN 1781
            ++AL NPFAP+R  ++ TSN RRW H FP+  + + IQ+HHQ   N  +L G  +++
Sbjct:  594 QRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRD 650

[Close]

BLAST of DEP domain-containing protein vs. UniProt/SwissProt
Match: sp|P61460|DEPD5_MOUSE (GATOR complex protein DEPDC5 OS=Mus musculus OX=10090 GN=Depdc5 PE=1 SV=2)

HSP 1 Score: 337.421 bits (864), Expect = 8.560e-93
Identity = 185/461 (40.13%), Postives = 285/461 (61.82%), Query Frame = 3

Query:   66 RLVFHKKL--KPEDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKS---SSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFIYEIPENSL 1424
            +LV HKK     +D+++   K F  I  G ++EI    ND++   L+++ ++  +  QK+TIS D  +    +L P + +   V++   +TLD++++  +DQY+ R DM+R    + ++   +++K++F G  R    E+W   ++   GY    TRVVFRS +++V+IFIQMS EMW+FD +G+LYF+KA+N F++DLF KW+  NC H++T+VLFSR FY   + +   +  + +I+ D  GRFYEDFY VVVQNER    EW  ++ T+K  F  Y   +   Q   F    N     S++   N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR    +TKQR+ D G+G+DLVC+GEQPLHAVPLF    +S    S + D+ Y IP+WINHSFY S ++L       F PRIK++ +KS+  EK    +D +    +  EN+L
Sbjct:    8 KLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAG-IRAQAGELWVKNEKVMCGYISEETRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSIDEFPEINRASIQEDHKGRFYEDFYKVVVQNERR--EEWTSLLVTIKKLFIQYPVLVRLEQAGGFPQGDN-----STSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRSVPRDSRLGDD-YNIPHWINHSFYTSKSQLFC---NSFTPRIKLAGKKSA-SEKTKNGRDTSLGTPKESENTL 453

HSP 2 Score: 268.47 bits (685), Expect = 3.537e-71
Identity = 260/988 (26.32%), Postives = 412/988 (41.70%), Query Frame = 3

Query: 2196 IGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNPPALNYSSTIFXXXXXX------XXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNY--CLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQN--SLIEEFFKFLEGINK----------IKRRSPNSKPKMSMPVIDNSSNLMNNPSMVKVKSVSGNLLEMKVSSSNMXXXXXXXXXXXXXXXXDKIDLLMLIQSYLIACEPSINSTLDNLVNVPSSGGSLNQHQKSAIQSACIVTNANPMSPSRPAVHHRHSTTHEPNHYNQLCELISNNSSNPVTPIEKYPRQFTFDSLENTMKSSSGLELDKLSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNIXXXXXXXXXXXXXXXDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ--LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            +GVDWKSLT PA LP+T+DY+P  + L++++ E  Y L+  +     +         +    VF+E I QRL QG+Q+I  P     ++T+     +         S    ++   Y   +GR FH + +K  +I VT+Y P++    A I Y Y  C    DS +F+     F  + LE++ WNY D YI + G      ++D   + LI SLKFWR+RF LLP   A  T        ++ CDIY DK   +++   L++ F +F+EG+N+          I++ +     +M+ P+  +S      P   K  S    LLEM+ S  ++      +         +   + M   +Y+ +      +     V  P +  S    Q S  Q+A +V ++  +  S      R +        NQ       NS N    IE+      F S  +   SS       L+ SS  V +LE M +   G+  L   +  +   F S E VHW ++ ++ +      +  +QK++  + I HAS  +   F+YGF FY +                                 E +     + +  W   Y    +     +R + E +F+   L     P        FL+  +P +       H +     G       L        + V LD++ +   +R EW    Y  N+    AFE  + W+  T   L E +  W +K +     LVPV   PFALPS +  DPLR  +F+PL++ CL++      S H         LFD F  E    R+ L QEAI  RFGF+++    YS      N   +N  +                       YIH +G +F  +P YSK +            +  + N +SS  +++  +E         +G+ W++N MLT+ W +     DE+F DR+L DF +FC N DNRL  F+
Sbjct:  730 VGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADMDRRDEEGVQ----MTAQQVFEEFICQRLMQGYQIIVQPKTQKPNTTVPPPLSSSPLYSRGLVSRNRPEEEGQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDS-EFVSCWVDFCHERLEEYKWNYLDQYICSAG------SED---FSLIESLKFWRTRFLLLP---ACVTATKRITEGEVHCDIYGDKPRADEDEWQLLDGFIRFVEGLNRIRRRHRSDRMIRKGTAMKGLQMTGPISAHSLEAAGPPVGKKGTSALSALLEMEASQKSLGEQQTTVHGKSSTQPAENSSVAM-TPTYVDSPRKD-GAFFMEFVRSPRTASSAFYPQASVDQTAPLVLDSTSLGVSTGQPMDRGN--------NQ----TFGNSQN----IEQ-----AFPSANSGDYSSQQHVASSLTSSSTLVEILEAMKHPSTGVQLLSEQKGLSPCCFISAEVVHWLMNNVEGVQTQAMGIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIV-----------------------------MDKEPERVAMQQPSAPW---YTAGADDFASFQRKWFEVAFVAEELVHSEIPA-------FLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTATVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNLSCLLKEG----SEH---------LFDSFEPETYWDRMHLFQEAIAHRFGFVQD---KYSVS--AFNFPAENKPQ-----------------------YIHVTGTVFLQLP-YSKRKFSGQ--------QRRRRNSTSSTNQNMFCEE--------RVGYNWAYNTMLTKTWRSS-ATGDEKFADRLLKDFTDFCINRDNRLVTFW 1579

HSP 3 Score: 62.7734 bits (151), Expect = 3.262e-8
Identity = 25/57 (43.86%), Postives = 38/57 (66.67%), Query Frame = 3

Query: 1611 RKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKN 1781
            ++AL NPFAP+R  ++ TSN RRW H FP+  + + IQ+HHQ   N  +L G  +++
Sbjct:  594 QRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSRQRD 650

[Close]

BLAST of DEP domain-containing protein vs. UniProt/SwissProt
Match: sp|Q54XA2|Y9099_DICDI (DEP domain-containing protein DDB_G0279099 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0279099 PE=3 SV=1)

HSP 1 Score: 234.958 bits (598), Expect = 1.548e-60
Identity = 136/382 (35.60%), Postives = 214/382 (56.02%), Query Frame = 3

Query:   69 LVFHKKLKPEDDILFTAKDFSFISKGSLLEIYQQENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDC--NSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIF 1205
            L  H +   +++++   + F  +    +L+IY   N    L       S  + K  IS    +         K +   ++ E    +D +++  +DQY+ RSDM+R   ++QN  + + KKL F    R  V EM  NGQ+  SG    +T+ VFRS ++   +FIQMS EMW++   GELYF+KA+N F+ +LF +W++ +  H +TI+LFSR F+ N   +++ D +  NI  +  G+ Y+DFY VVV  E     +W  +I  LK  FN+Y T +      N+D    ++     S+A   NFLE +N+ ++ ++ +YIDR+F RTG++ VVI+AG+G++ VD     ITKQR+ D G+G DL+C+   PLH VPLF F
Sbjct:   12 LWVHDQQFSKEELVVNPEYFPKLKIMDVLKIYSPSNPSKRLCLRVKQLSPLKTKLQISISKYVAGVFDFALRKEVVVNIIPEKQAIIDFVELSFKDQYIGRSDMWRLKLNLQNECVYVLKKLAFA-QIRAQVEEMVSNGQKVSSGLIDDSTKFVFRSRSAKFVLFIQMSKEMWDYSPDGELYFEKAVNGFLKNLFQRWKSLSVNHTITIILFSRTFHEN---DDILDEIP-NIPRNPQGKLYQDFYKVVVNEE--TRPDWSSIIVNLKREFNDYHTSV------NWDIYGRNSALGKNSTASQGNFLEAINLGMSYFDKHYIDRDFTRTGQMIVVISAGTGIFEVDPDINLITKQRMIDNGIGCDLICLNNHPLHVVPLFKF 380

[Close]

BLAST of DEP domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4PE51|IML1_USTMA (Vacuolar membrane-associated protein IML1 OS=Ustilago maydis (strain 521 / FGSC 9021) OX=237631 GN=IML1 PE=3 SV=1)

HSP 1 Score: 201.06 bits (510), Expect = 2.814e-50
Identity = 110/351 (31.34%), Postives = 194/351 (55.27%), Query Frame = 3

Query:  201 DNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTEL--------------EQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFR 1208
            D V   PQ +  IS    + N+             + ++  T+D +++  RDQY+ R++M+R   +++++ +   +K+   G  R T+  ++   ++  SGY  A+T+ +FRS ++  ++FIQ+S EMWEFD  GE+Y++KA+  FI +L  +W+     H +T++LF+R+ Y     E+    ++  I+ D  G++Y D+Y VVV  E      W  V+ TLK  F  ++ ++              E+   +      +    +SS+ + N LE +N+ LN ++ +YIDR+  RTG   V +TAG+G ++VD+    IT +R+ + G G+DLVC+ + PLH+VPLF F+
Sbjct:  120 DFVARQPQLQ--ISVSKNIANNYGFYNRAEAILTRVTKDDFTIDHVELYFRDQYVGRAEMWRVFQNLEDTCVYCGQKVTLAGSVRATIGRIFIKEKKVTSGYVSASTKAIFRSESAKYNLFIQLSREMWEFDEDGEIYYEKALQGFIPELLRRWRAVPTNHILTVILFARVHY----DESEIHMLEGPIRQDARGKYYIDYYKVVVDLESNC--NWDAVMTTLKEEFFRFQHDILLIRRPISGPAASHEELHADLIRDRVHMAGRISSSYEGNLLEAINLALNPFDEHYIDRDLNRTGLSMVFLTAGTGHFDVDKKLLRITTERMIENGTGLDLVCLTKMPLHSVPLFHFK 462

[Close]

BLAST of DEP domain-containing protein vs. TrEMBL
Match: A0A132AEU0 (DUF3608 domain-containing protein OS=Sarcoptes scabiei OX=52283 GN=QR98_0080000 PE=4 SV=1)

HSP 1 Score: 447.203 bits (1149), Expect = 4.924e-128
Identity = 342/1023 (33.43%), Postives = 517/1023 (50.54%), Query Frame = 3

Query:   63 CRLVFHKKLKPEDDILFTAKDFSFISKGSLLEIYQ-QENDKHHLIKIDNVNSNPQQ--KDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAI-NFISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFI---YEIPENSLNFVRKLSKPEIVSDNISGV-----ISTSNNCERGGLYHGSYGSHNSKDDTFINPIKPGHKRIIQSDHRKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKNSKNMAEAWKNYYKLYTEANNKXXXXXXXXXXXXXXXXXXXPKSPFRETDDSSVIMEKAEFHIINDK--ISDDSIGVSLLPXXXXXXXXXXXXXXXXXIKGSINRRVHT-LFTEGEQKWSWDQPKEDE-SPINHLDVEESIKLIGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXX------XXXXXXXHRKP--LGIHDVFQELIYQRLNQGFQMITNPPALNYSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXX---RCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRRSPNSKPKMSMPVIDNSSN 3050
             +L  H++   +DDI+   KDF  I  G ++EIY   +N    L++I N           TIS +  +  + +L     +   V+++N + LD +++  +DQYLSRSDM+R   H+ N+ + ++KK++F    R  V EMW  G R  SGY    T++VFRSA+S       MS+EMW++D  G+LYF+KA+  F+SDLF KW+ +NC HD+TIVLFSR FY+  +     ++++  ++ D  GRFYED+Y V VQNER+  ++W   +  L+  FN Y+ ++  + +      +N   Y S+A   NFLE LN++LN++E + +DR+F+RTG++ VVI+ G GVY VD   T+ITKQRI D G+G DLVC+GEQPLHAVPLF F  +  SNI ++ Y +P+WIN SFY S   +       FIPRIK+    S+ I    +  + N  I   ++I  +S N  +KLS  + +   +S +      S S + E   L + ++    SKDD  +   +    R       KAL NPF P+   ++  SN RRW+HVFP+      +Q HH  A+  P      + +S  M ++ +         NN                     ++ F +  DS V  +K     IN+K  I D +  ++L          Q +      I+   +++  + L T+    W+W    E E +P             GVDWKSL +PA LPIT+D+ P  R L+ +++   Y L+    +S       S+ + +   KP  L     ++ELI+QRL QGFQ+I  P   N  +            +        Y   +GRI+H +  K++ I +  Y PRH     +I Y Y ++ PD+  + +S   F+++ LE + WNY D+YI   G        D   Y L  SLK+WR R  +LPT  +    I           +CDIYD  S  E+  L + F K L+ IN IK       P +    I  SSN
Sbjct:    4 VKLNTHQRNHYQDDIVICQKDFPDIKIGDVVEIYSIDDNFSRLLLQITNTEKLKANCTSPTISIEQSIAMTFQLRNFSDVIMNVIDKNTVPLDSVELFFKDQYLSRSDMWRLRKHLTNTCVHLNKKVEFSN-IRCQVFEMWSQGCRMASGYINDETKIVFRSASS------MMSSEMWDYDINGDLYFEKAVKGFLSDLFNKWKTFNCSHDVTIVLFSRTFYQASDINEFPESMRECLQQDYKGRFYEDYYRVAVQNERF--DDWTPTLIYLRELFNLYEEDVIHYHERR--GFTNVRPYNSTASQGNFLEVLNMSLNVFERHNLDRSFDRTGQLSVVISPGVGVYEVDLDLTNITKQRIIDNGIGSDLVCLGEQPLHAVPLFKFISR-HSNIPNDEYNMPHWINLSFYSSKQSISL-SSNSFIPRIKMPNIDSNPITISNRRDNSNGSILINHKITSSSKNSSQKLSSIDTIDGFVSYIPKNNSFSLSTSVE-NKLNNENHIKIKSKDDIVVYNSRDEQHRT------KALINPFDPSHVTIKLNSNRRRWTHVFPLGPTGIFMQQHHYQAV--PQKKSLLQNDSNAMYDSNEILNGKLKNLNN---------------------RTSFDQI-DSPVTTQKT----INNKNCIGDGNKKLTL-------NKRQSTSESEKKIENDFHQKQRSQLLTDNSLLWAWGATGEQEWTP---------AITTGVDWKSLVMPACLPITTDFLPDKRTLQQDYVTYVYDLLPEEQSSYNDQYRFSKSDEKFETKPTILTNDQFYEELIFQRLQQGFQIIFLPKQDNRYAI-----------NDRTGNKFTYILSIGRIYHELAHKENKISIIYYHPRHPYKANNIRYCYRIRTPDNSTYGVSWVDFNSEKLETYKWNYLDNYICLKG--------DYAEYPLTESLKYWRFRLLVLPTQQSKTKKIIDKYLSGEDDFQCDIYDILSFEEKIHLQKGFIKLLKVINGIKL------PLLKAQTISQSSN 937

HSP 2 Score: 128.257 bits (321), Expect = 1.174e-25
Identity = 88/305 (28.85%), Postives = 145/305 (47.54%), Query Frame = 3

Query: 4200 YKKVVLDIESELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXX-XXXXXXXXQLVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKY--RDINDLITLPVKIEETQSNLSSS---YTRHVN--TDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            +K   +D+E +  +R EW   +Y + Y P  AFE +++W+VATG  + + ++     K + L +VP+P DPFALP S  SDPLRGPI++ L+I+CL                       +  + E+L+     QE IL +FGF+                                     D  T     ++H SG +F +IP+ +    + I++     +K  E +   S      TRH +    +D D+   + IGFLW WN ++T++W T  +  DE    +++ DFR FC+N ++RL++F+
Sbjct: 1148 FKNFTIDLEQK-TDRVEWVNVKYHSLYDPEQAFELLIEWMVATGNAIPDIVATWGRTKGTNLHIVPIPWDPFALPFSSRSDPLRGPIYISLNIDCL--------------------QLSKMLEGEKLFN---FQEKILVKFGFLP----------------------------------FHDPSTDNQRQFVHVSGSIFVLIPNKTAVSSQKISNKRGKFLKTNEPKLACSPHEEYITRHFSGMQQKDEDAHIDIKIGFLWCWNYLITKRWKTN-VTGDENSMRKIMKDFRGFCSNKNDRLQEFW 1393

[Close]

BLAST of DEP domain-containing protein vs. TrEMBL
Match: A0A2T7PE36 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_07099 PE=4 SV=1)

HSP 1 Score: 435.261 bits (1118), Expect = 8.499e-123
Identity = 244/631 (38.67%), Postives = 356/631 (56.42%), Query Frame = 3

Query:   63 CRLVFHKKLKPEDDILFTAKDFSFISKGSLLEIYQQEND-KHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITD--NHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNF-----------IYEIPE---------------------NSLNFVRKLSKPEI--VSDNISGV---------------------ISTSNNCERGGLY--------HGSYGSHNSKDDTFINPI------KPGHKRIIQS-DHRKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHH 1733
            C+L  H+  K + DI+   KDF  +  G +LEIY  E +    L+++D++  + QQKDTIS D  + N+ KL   + +         + LD+++++ ++QY +RSDM+R ++ ++N+ + ++KK++F    R  V+EMW  G +   G    +TRVV+RS+T+VV IFIQMS+EMWEFD  G+LYF+KA+N F++DLF KW+  NC HD+TIVLFSR  Y + + ++   +++  +++D+ G  YED+Y V+VQNERY   EW   ++ L+  FN Y   + ++ QN +       + +S+A   NFLETLN++LNL+ENYY+DRNF+RTGKV VVIT G GV+ VDR  T ITKQR  D GVG DLVC+GEQPLHAVPLF FR K+S N  +  + Y IP+W+NHSFY S +++Q  Q  KFIPRIK   E    + K  + ++DNNF           ++++P                      ++    R++  P    VSD+  GV                     +++ +     G Y          S+ S  S D  F  P+        GH R        +AL NPFAP+R   + TSN RRW H  P D     +Q HH
Sbjct:    5 CKLWVHRNTKSQQDIIIPPKDFPGVMIGDVLEIYHPEEEFSRLLLQVDSLPEDFQQKDTISIDQSIANTFKLRAYQDVVVTKTEPQNVALDMVELLFKEQYFNRSDMWRLVNSVKNTCVYLNKKIEFSE-MRCQVNEMWSKGDKVTCGVITEDTRVVYRSSTAVVQIFIQMSSEMWEFDLNGDLYFEKAVNGFLTDLFAKWKEQNCCHDVTIVLFSRTCYSSTSLDDFPSDIRECLQVDDFGNIYEDYYRVIVQNERY--EEWNNTLRLLRKLFNEYPERVLRYHQNQWPKWKFPAARISTASQGNFLETLNMSLNLFENYYLDRNFDRTGKVSVVITPGPGVFEVDRELTFITKQRTIDCGVGSDLVCMGEQPLHAVPLFKFRSKNSQNSVEVGDDYNIPHWMNHSFYTSKSQIQNQQSAKFIPRIKPPPEFVKFLLK-TEGREDNNFPFVDYDEYDAQVFKLPSRMFQRTSRSASCFTSRLAAKHHTFAEARRMCGPRTRHVSDDFMGVTVDSSDKKTKMSSSAIAIPSTLTSPDTSYSVGCYPIYEKHISQESFDSWGSDDIPFPRPVVGSAGSPVGHSRPSGGFPPNRALINPFAPSRLQFKMTSNRRRWVHALPTDAKGLTVQPHH 631

HSP 2 Score: 163.696 bits (413), Expect = 1.751e-36
Identity = 115/313 (36.74%), Postives = 158/313 (50.48%), Query Frame = 3

Query: 4185 KNGILYKKVVLDI-ESELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXX--QLVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSY--SKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETV----NIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFYLD 5096
            K  +L+K V +D+  S   +R EW    Y A Y P  AFE  +QW+VATG  L E I  W++K       L+PVP DPFALP+ +NSDPLR PIFVPL+++               + D+ + +F + S E R  RL+L+Q+ ILKR+GF+R   IN    D          T N   K +    L           Y+H + GMF +IP    S   + +     P     +     S+   H N      S + +    ++GFLWSWN M +++W +G    DE FQD+MLADFREFC N D RL+ F  D
Sbjct: 1284 KATLLHKYVNVDVNPSGKSDRQEWASACYNAYYSPLCAFEIQIQWMVATGCILGETIYSWARKAGPCGFHLIPVPVDPFALPNCVNSDPLRSPIFVPLAVD--------------DVEDS-ESIFTDCSSEVRQERLLLIQDTILKRYGFVR---INVPVPD-------PGKTDNSSSKSLSSQHLYMQ---EYVHQYVHCTAGMFVLIPDLYPSLLSNAHGPARYPPSPTVSYVAKKSTSDMHKNYIARQQSSQKMIQNHHVGFLWSWNFMSSKRWRSG-STGDEAFQDKMLADFREFCQNKDGRLEAFLKD 1567

HSP 3 Score: 160.614 bits (405), Expect = 1.814e-35
Identity = 101/295 (34.24%), Postives = 153/295 (51.86%), Query Frame = 3

Query: 2169 LDVEESIKLIGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAX---XXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMI--------TNPPALNYSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRRSPNSKPKM 3020
            LD +   + I VDWKSLT+PA LPIT+DY+P +  L+ +++ ++Y L+ +   +     +      R PL  H+VF+ELI QRL QGFQ+I        ++ P++  S   F        + + +D    Y   +GRIFH + +K   I VT+  PRH       TY Y  + PDS  +  S T+F  + LE +NW+Y D YI   G            + L   LK+WRSRF+LLP+++           +  RCDIY++K+  E   L   F +F E +NK+KR   + + K+
Sbjct:  778 LDSDNFCQGISVDWKSLTMPACLPITTDYFPESGSLQYDYVFADYSLLPDDINADQLYDKNLKFYRRPPLTTHEVFRELISQRLGQGFQLIVSKKNGKKSDTPSVAKSQQ-FQHVTGMMQARQKEDSEEEYYLSIGRIFHNLHLKGSTITVTKSWPRHPQPKRTYTYFYRFQAPDSYCYDASSTEFFNEQLENYNWSYLDQYICTRGE---------ADHGLADFLKYWRSRFFLLPSNNT--ATKKIIDGQSSRCDIYEEKTPAELKQLTMSFVRFCEVLNKLKRLPQSRRTKV 1060

HSP 4 Score: 71.633 bits (174), Expect = 2.346e-8
Identity = 34/91 (37.36%), Postives = 52/91 (57.14%), Query Frame = 3

Query: 3537 DKLSDSSPYVRVLEEMMNSQNGLTFLQS-PEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFY 3806
            D+L+ SSP  +++E M++ Q GL+F+Q  P  P   TF S EAV WC   +        A + +Q+L++ + + HAS    H F+YGF  Y
Sbjct: 1095 DRLTQSSPSSKIVEAMLDPQTGLSFIQGQPGLPGN-TFISAEAVAWCQQHVSGAQTTAQATMVIQRLVDDQLVLHASGNPRHMFIYGFYLY 1184

[Close]

BLAST of DEP domain-containing protein vs. TrEMBL
Match: A0A0L8FG79 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22022561mg PE=4 SV=1)

HSP 1 Score: 399.053 bits (1024), Expect = 9.918e-117
Identity = 242/636 (38.05%), Postives = 345/636 (54.25%), Query Frame = 3

Query:   66 RLVFHKKLKPEDDILFTAKDFSFISKGSLLEIY-QQENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITD--NHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIE--KLAKPKD--------DNNFIY----------------EIPENS---------------LNFVRKLSKPEI--VSDNISGV----------------ISTSNNCERGGL-----------YHGSYGSHNSKDDTFINPI------KPGHKRIIQSDHRKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHH 1733
            +L  H++   E D+L   KDF  I++G +LEIY  Q N    L++++ +  + Q K+ IS +S +  +  L P   +    ++   ++LD+++++ ++QY SRSDM+R    + N+   ++KK++F    R  VSE+W  G+R   G    NTR+VFRS+T+VV IFIQMS+EMW+FD  G+LYF+KA+N F++DLF KW+  NC HD+TIVLFSR FY   + +   + ++  I+ D  GRFYEDFY VVVQNERY   +W   +  L+  FN Y  ++ ++ +         E+  S+A   NFLETLN++LNL+E YY+DR+F+RTG+V VVIT G GV+ VDR  T+ITK R  D G+G DLVC+GEQPLHA PLF F  K+     +  + Y IP+W+NHSFY   + L   +   FIPRIK       ++E  K+   +D        DN+F +                 +P  S               +  V+K  KP    +SD+ SG+                I   N+ E G              H  +G  +S D T   PI        GH R      RKAL NPFAP+R   + TSN RRW H FP D +   +Q HH
Sbjct:   11 KLYVHERNFKEYDLLINPKDFPGINQGDVLEIYNAQVNYSRLLLQVNTLTEDLQAKECISVESSIAGAFHLKPYNDVYVNKVDPTEVSLDLVELLYKEQYYSRSDMWRMRKKLVNTCAYLNKKIEFAE-MRCQVSELWSKGERVTCGVIDDNTRIVFRSSTAVVQIFIQMSSEMWDFDVHGDLYFEKAVNGFLTDLFAKWKEQNCCHDVTIVLFSRTFYSASSCDEFPEIIRDWIQQDYKGRFYEDFYRVVVQNERY--EDWASTLIQLRVIFNEYPQKVVRYHEACGLTVPPAEN--STASQGNFLETLNMSLNLFERYYLDRSFDRTGQVAVVITPGPGVFEVDRELTNITKHRTIDCGIGSDLVCMGEQPLHAAPLFKFHSKTEKITLEVGDDYNIPHWMNHSFYTFKSPLLGTE-STFIPRIK----PPKILEDIKMKSKEDVYSSSYYSDNDFTFIDYDGYDTQVFKFPSRGVPRTSKGSGHFSSLRKRPTTVAEVKKNRKPRTRYISDDFSGLFTENTPKSTATSPAISIPIQNSTELGSPIVSYPLTDRSNAHDFFGLADSDDCTITRPIVGSAGSPVGHSRNYHHRPRKALINPFAPSRMRFKMTSNRRRWVHAFPTDPSGAAVQTHH 636

[Close]

BLAST of DEP domain-containing protein vs. TrEMBL
Match: A0A0L8FG47 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22022561mg PE=4 SV=1)

HSP 1 Score: 389.423 bits (999), Expect = 3.113e-113
Identity = 241/645 (37.36%), Postives = 346/645 (53.64%), Query Frame = 3

Query:   66 RLVFHKKLKPEDDILFTAKDFSFISKGSLLEIY-QQENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITD--NHYYIPYWINHSFYRSVNELQAIQMGKFI-----PRIKVSFEK----SSLIE--KLAKPKD--------DNNFIY----------------EIPENS---------------LNFVRKLSKPEI--VSDNISGV----------------ISTSNNCERGGL-----------YHGSYGSHNSKDDTFINPI------KPGHKRIIQSDHRKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHH 1733
            +L  H++   E D+L   KDF  I++G +LEIY  Q N    L++++ +  + Q K+ IS +S +  +  L P   +    ++   ++LD+++++ ++QY SRSDM+R    + N+   ++KK++F    R  VSE+W  G+R   G    NTR+VFRS+T+VV IFIQMS+EMW+FD  G+LYF+KA+N F++DLF KW+  NC HD+TIVLFSR FY   + +   + ++  I+ D  GRFYEDFY VVVQNERY   +W   +  L+  FN Y  ++ ++ +         E+  S+A   NFLETLN++LNL+E YY+DR+F+RTG+V VVIT G GV+ VDR  T+ITK R  D G+G DLVC+GEQPLHA PLF F  K+     +  + Y IP+W+NHSFY   + L   +   FI     P+I          +S++E  K+   +D        DN+F +                 +P  S               +  V+K  KP    +SD+ SG+                I   N+ E G              H  +G  +S D T   PI        GH R      RKAL NPFAP+R   + TSN RRW H FP D +   +Q HH
Sbjct:   11 KLYVHERNFKEYDLLINPKDFPGINQGDVLEIYNAQVNYSRLLLQVNTLTEDLQAKECISVESSIAGAFHLKPYNDVYVNKVDPTEVSLDLVELLYKEQYYSRSDMWRMRKKLVNTCAYLNKKIEFAE-MRCQVSELWSKGERVTCGVIDDNTRIVFRSSTAVVQIFIQMSSEMWDFDVHGDLYFEKAVNGFLTDLFAKWKEQNCCHDVTIVLFSRTFYSASSCDEFPEIIRDWIQQDYKGRFYEDFYRVVVQNERY--EDWASTLIQLRVIFNEYPQKVVRYHEACGLTVPPAEN--STASQGNFLETLNMSLNLFERYYLDRSFDRTGQVAVVITPGPGVFEVDRELTNITKHRTIDCGIGSDLVCMGEQPLHAAPLFKFHSKTEKITLEVGDDYNIPHWMNHSFYTFKSPLLGTE-STFIPRIKPPKIPGHLPHGGNCASVLEDIKMKSKEDVYSSSYYSDNDFTFIDYDGYDTQVFKFPSRGVPRTSKGSGHFSSLRKRPTTVAEVKKNRKPRTRYISDDFSGLFTENTPKSTATSPAISIPIQNSTELGSPIVSYPLTDRSNAHDFFGLADSDDCTITRPIVGSAGSPVGHSRNYHHRPRKALINPFAPSRMRFKMTSNRRRWVHAFPTDPSGAAVQTHH 649

[Close]

BLAST of DEP domain-containing protein vs. TrEMBL
Match: A0A1S3HEX7 (GATOR complex protein DEPDC5 OS=Lingula unguis OX=7574 GN=LOC106153972 PE=4 SV=1)

HSP 1 Score: 395.586 bits (1015), Expect = 7.888e-110
Identity = 221/560 (39.46%), Postives = 322/560 (57.50%), Query Frame = 3

Query:  315 NLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITD--NHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEK---------SSLIEKLAKPKDDNNF---------IYEIPEN-------------------------SLNFVRKLSKP--EIVSDNISGVISTSNNCERGGLYHG------------------------------SYGSHNSKDDTFINPI------KPGHKRIIQSDH--RKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQ 1736
             +++LD++++II+DQYLSRSDM+RF   ++N+ + + KK+DF G  R  V+E+W  G +   GY   +TR+V+RS+T+VVHIF+QMS+EMWEFD FG+LYF+KA++ F++DLF+KW+  NC HD+TIV+FSR FY   + E+  ++++  I+ D  GRFYEDFY VVVQNE Y   EW  V+  LK  F +Y     Q+ Q+        +++ S+A   NFLE LN++LN+YE YYIDRNF+R GKV +V+T G+GV+ VDR  T +TKQR  D G+G DLVC+GEQPLHAVPLF F   + ++  D  + Y+IP+WINHSFY S +++Q      F+PRIK++  K          ++++ +++  D   F         ++++P +                         SLN    + +P    +SD++SG++S   +  +     G                              S GS +S DD    P+        GH    Q  H  R+AL NPFAP+R   + TSN RRW H FP+D+    I  HHQ
Sbjct:    2 TVVSLDLMELIIKDQYLSRSDMWRFTKSLRNTCMYVGKKVDFIG-MRAQVNELWAKGDKMTCGYVSEDTRIVYRSSTAVVHIFLQMSSEMWEFDAFGDLYFEKAVSGFLTDLFVKWKEQNCLHDVTIVMFSRTFYDAHSLEDFPESMRECIQQDYKGRFYEDFYRVVVQNECY--KEWTGVLVDLKQFFIDYPKTTIQYHQDQ--GAKVPKAWNSTAAMGNFLEVLNMSLNVYEKYYIDRNFDRLGKVAIVVTPGAGVFEVDRELTTMTKQRTIDTGMGSDLVCMGEQPLHAVPLFRFHSSTPNDFLDVGDDYHIPHWINHSFYTSRSQIQTTSSLSFVPRIKLAKMKPNVKDKEDIENIVDGMSEEDDRLPFVDYDEYDAQVFKLPNSRTRTPKSRNTRSAASLYSSARKTPQSLNEAMAIKRPRNRTISDDVSGLLSDDQSVGKRSPAIGIPGKVKSADLLSTSLGTIPIPLAEISTSQHSVGSEDS-DDFMERPVVGSAGFPAGHHLPAQFRHPPRRALINPFAPSRMRFKMTSNRRRWVHAFPLDQQGAAILPHHQ 555

HSP 2 Score: 187.578 bits (475), Expect = 9.270e-44
Identity = 108/335 (32.24%), Postives = 173/335 (51.64%), Query Frame = 3

Query: 2112 GEQKWSWDQPKEDESPINHLDVEESIKLIGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNPPALN-------YSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRRSPNSKPKMSMPVIDNSSNLMNNPSMVKVKSVSG 3095
            G + W W        P+            GVDW+S++LPA+LP+++D++P  R L ++++ S Y+L+ +  NS+     +S+++P+   +VF+ELIYQR  QGFQ+I  P   +        +S ++    +   +     ++  Y+  +GRI+H + +    I V +Y PRH   L  + Y Y  K PDS ++ +S   F  Q LE +NWNY D+YI   G            Y L+ SLK+W+SRF LLP H+          +   RCD+Y++KS+ EQ  + E F K LE +NKI+R     KP ++ PV  +S+ +    +  K  S   
Sbjct:  689 GSKSWQW-------GPVTGEQEWSPTITTGVDWRSMSLPAVLPMSTDFFPDKRSLHNDYVISEYKLLPDVINSDISYECRSNKRPMTTMEVFKELIYQRFGQGFQVIVGPKNSSPNNQSDLSTSPMYKGTASLIRARSRTIQSEEYRLSIGRIYHKVNLTGPEITVVRYRPRHPYTLRTVHYKYRFKCPDSVNYDVSWVTFKNQQLENYNWNYLDNYICTKGEG---------DYGLMESLKYWKSRFLLLPCHNP---ATKKIIDGAERCDVYEEKSLEEQQQMTEGFVKILEMLNKIRRPGQGRKPGLT-PVSADSTVIAPADATAKTDSTPA 1003

HSP 3 Score: 183.341 bits (464), Expect = 1.468e-42
Identity = 115/320 (35.94%), Postives = 161/320 (50.31%), Query Frame = 3

Query: 4200 YKKVVLDIE--SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXX--XXXXXXXXXQLVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITL-------PVKIEE--TQSNLSSSYTRHVNTDED----------SDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            YK + +D +  S+ G R EW   +Y ANY+P  A+E  + WLV TG  L E +S  +         L+ VP DPFALP + NSDPLRGPI+VPL+++CL +             D I  +F E+  + R  RL LLQE ILKRFGF+ +SC+  + +   LN Q  +T                         ++H +GGMF MIP  +      +   L       P  + +  T+SN    Y        D          S   E + +GFLW WN ML+++W + P   DE FQD++LADFR FC+N DNRL++F+
Sbjct: 1191 YKHIKIDTDPASKCG-RPEWCTMRYHANYNPLCAYELTLNWLVCTGPVLGELVSGWVRKVSTCSYHLLAVPVDPFALPYTDNSDPLRGPIYVPLNVQCLTD-------------DEISPVFSEYDSDSRSERLRLLQEFILKRFGFMLDSCLVQTPRP--LNYQSDDTKPQ----------------------WVHCTGGMFVMIPDSAASAIPENSTCLTDRRMPNPTAMHKLFTKSNAHKDYIERQRNRADSVNISFSSDISAGTEDIKVGFLWCWNSMLSKRWRS-PNTGDESFQDKVLADFRAFCSNQDNRLREFW 1471

HSP 4 Score: 63.5438 bits (153), Expect = 6.204e-6
Identity = 31/93 (33.33%), Postives = 50/93 (53.76%), Query Frame = 3

Query: 3528 LELDKLSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFY 3806
            ++ +KLS SSP   VL++M +  NGL FL   E     +F S+EA  W    ++      +AV  LQ +++ K I H    + H++++GF  Y
Sbjct: 1010 IQEEKLSMSSPLSAVLKKMQDPSNGLKFLPVQEGLPSQSFVSFEATEWVQENVEGAAGFPTAVALLQTMVDEKMICHGCRNTRHRYIHGFYLY 1102

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Cavefish
Match: depdc5 (DEP domain containing 5, GATOR1 subcomplex subunit [Source:ZFIN;Acc:ZDB-GENE-091204-356])

HSP 1 Score: 327.791 bits (839), Expect = 8.575e-91
Identity = 180/459 (39.22%), Postives = 281/459 (61.22%), Query Frame = 3

Query:   69 LVFHKKL--KPEDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLF-SRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITD-NHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFIYEIPENSL 1424
            LV HKK     +D+++   K F  +  G ++EI    ND++   L+++ ++  +  QK+TIS D  +  + KL   + +   +++   +TLD++++  +DQY+ R DM+R    + ++   +++K++F G  R   SE+W  G++   GY   +TRVVFRS +++V+IFIQMS EMW+FD +G+LYF+KA+N F+SDLF KW+  NC H++T+VLF + L Y         ++ + +I+ D  GRFYEDFY VV QNER   +EW  ++ T+K  F  Y   +     + F C  N     S+A   N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR    +TKQR+ D G+G+DLVC+GEQPLHAVPLF    ++    +  + Y +P+WINHSFY S ++  +     F PRIK++  K    EK    KD +    +  ENSL
Sbjct:   12 LVVHKKGFGGSDDELMMNPKVFPQVKLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETISVDQTVAQAFKLRAYQDVIINIVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYVTQKVEFAG-IRAQASELWVKGEKVTCGYISEDTRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLSDLFAKWKEKNCSHEVTVVLFLTYLLY------EFPESQRGSIRQDHEGRFYEDFYRVVAQNERR--DEWTSLLITIKKLFIQYPVLVRLKGADGFPCGQN-----STAAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRTVPGDSRLDDYNLPHWINHSFYTSKSQGSS---SCFTPRIKLAGRKLH-AEKSKSSKDHSLGAQKDSENSL 450

HSP 2 Score: 147.517 bits (371), Expect = 6.437e-35
Identity = 138/508 (27.17%), Postives = 217/508 (42.72%), Query Frame = 3

Query: 3579 EMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNIXXXXXXXXXXXXXXXDESDNFIKSKNNIEWVEVY-LCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ--LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            +++  Q GL        PN   F S E VHW ++ ++ +     AV  +QK+++   + HAS  +   F+YGF FY + +                               ESD      N +    V+   ++E     +R + E +F+      + +P D      FL+  +P +       H +     G       L        K V LD++ +   +RAEW    YQ N+    AFE  + W+  T   L E +  W +K +     LVPV   PFALPS +  DPLR  +F+PL+I+ L             + D+ D LFD F  E    R+ L QEAIL RFGF+++    +S+     N   +N  +                       YIH +G +F  +P YSK +            +  + N +SS ++ +   E+        +G+ W++N MLT+ W TG ++ DE+  DR+L DF +FC+N DNRL  F+
Sbjct: 1107 QLLPEQKGLP-------PN--CFISAEVVHWLMNTVENVATQGIAVEIMQKMLDDGLVAHASGDAMRTFIYGFYFYKIVD------------------------------KESDKV--PTNQLPPAGVWSTAAVEDFALFQRKWFEVAFV----LEERRPCDLP---AFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQKTVTLDVDVNNRSDRAEWCSCYYQGNFSLNSAFEIKLHWMAVTAAVLFEMVQGWHRKAASCGFLLVPVLEVPFALPSYLYGDPLRAQLFIPLNIQSL-------------LRDSSDSLFDGFEPETYWDRMQLFQEAILYRFGFVQD---KFSAS--AFNFPAENKPQ-----------------------YIHVTGTVFMQLP-YSKRK-------YSCGQQRRRRNSASSASQSLFGCEE-------RVGYNWAYNTMLTKAWRTG-VLGDEKLADRLLRDFTDFCSNKDNRLVAFW 1509

HSP 3 Score: 110.923 bits (276), Expect = 9.337e-24
Identity = 79/274 (28.83%), Postives = 128/274 (46.72%), Query Frame = 3

Query: 2196 IGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRK---PLGIHDVFQELIYQRLNQGFQMITNPPALNYSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKD-FMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQN--------SLIEEFFKFLEGIN 2981
            +GVDWKSLT PA LP+T+DY+P  + L++++ E  Y L+ ++                 PL I       I+ RL                           S  K +++ +++   +GR FH + +K  +I VT+Y P++      I Y+Y L  P ++  F+    +F  + LE++ WNY D YI + G      ++D   + LI SLKFWR+RF LLP   A         + +   D+Y D     ++        +L++ F +FLEG+N
Sbjct:  732 VGVDWKSLTTPACLPLTTDYFPDRQTLQNDYTEGCYDLLPHTDLDRYTHTYTGTHTAPVPLPIDLSIHPCIHSRL--------------------------VSRRKAEEEESLFWLSMGRTFHKVCLKDKIITVTRYLPKYPYESTQIQYSYSLCPPHAEGHFVPCWVEFGHERLEEYKWNYLDQYICSAG------SED---FSLIDSLKFWRTRFLLLPAGGA-----RRVADGEGHWDVYGDGPGAGRDGFGASGDWALLDGFIRFLEGLN 965

HSP 4 Score: 64.6994 bits (156), Expect = 1.033e-9
Identity = 26/57 (45.61%), Postives = 38/57 (66.67%), Query Frame = 3

Query: 1611 RKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKN 1781
            ++AL NPFAP+R  ++ TSN RRW H FP+    + IQ+HHQ   N  +L G E+++
Sbjct:  592 QRALINPFAPSRMPMKLTSNRRRWMHTFPVGPTGEAIQIHHQTRQNMAELQGSEQRD 648

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Cavefish
Match: depdc5 (DEP domain containing 5, GATOR1 subcomplex subunit [Source:ZFIN;Acc:ZDB-GENE-091204-356])

HSP 1 Score: 327.405 bits (838), Expect = 8.914e-91
Identity = 180/459 (39.22%), Postives = 281/459 (61.22%), Query Frame = 3

Query:   69 LVFHKKL--KPEDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLF-SRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITD-NHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFIYEIPENSL 1424
            LV HKK     +D+++   K F  +  G ++EI    ND++   L+++ ++  +  QK+TIS D  +  + KL   + +   +++   +TLD++++  +DQY+ R DM+R    + ++   +++K++F G  R   SE+W  G++   GY   +TRVVFRS +++V+IFIQMS EMW+FD +G+LYF+KA+N F+SDLF KW+  NC H++T+VLF + L Y         ++ + +I+ D  GRFYEDFY VV QNER   +EW  ++ T+K  F  Y   +     + F C  N     S+A   N+LE +N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR    +TKQR+ D G+G+DLVC+GEQPLHAVPLF    ++    +  + Y +P+WINHSFY S ++  +     F PRIK++  K    EK    KD +    +  ENSL
Sbjct:   12 LVVHKKGFGGSDDELMMNPKVFPQVKLGDIVEI-AHPNDEYSPLLLQVKSLKED-LQKETISVDQTVAQAFKLRAYQDVIINIVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYVTQKVEFAG-IRAQASELWVKGEKVTCGYISEDTRVVFRSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLSDLFAKWKEKNCSHEVTVVLFLTYLLY------EFPESQRGSIRQDHEGRFYEDFYRVVAQNERR--DEWTSLLITIKKLFIQYPVLVRLKGADGFPCGQN-----STAAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRTVPGDSRLDDYNLPHWINHSFYTSKSQGSS---SCFTPRIKLAGRKLH-AEKSKSSKDHSLGAQKDSENSL 450

HSP 2 Score: 149.828 bits (377), Expect = 1.267e-35
Identity = 137/511 (26.81%), Postives = 218/511 (42.66%), Query Frame = 3

Query: 3570 VLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNIXXXXXXXXXXXXXXXDESDNFIKSKNNIEWVEVY-LCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ--LVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            +LE + +   G+  L   +      F S E VHW ++ ++ +     AV  +QK+++   + HAS  +   F+YGF FY + +                               ESD      N +    V+   ++E     +R + E +F+      + +P D      FL+  +P +       H +     G       L        K V LD++ +   +RAEW    YQ N+    AFE  + W+  T   L E +  W +K +     LVPV   PFALPS +  DPLR  +F+PL+I+ L             + D+ D LFD F  E    R+ L QEAIL RFGF+++    +S+     N   +N  +                       YIH +G +F  +P YSK +            +  + N +SS ++ +   E+        +G+ W++N MLT+ W TG ++ DE+  DR+L DF +FC+N DNRL  F+
Sbjct: 1080 ILEAIKHPTTGVQLLPEQKGLPPNCFISAEVVHWLMNTVENVATQGIAVEIMQKMLDDGLVAHASGDAMRTFIYGFYFYKIVD------------------------------KESDKV--PTNQLPPAGVWSTAAVEDFALFQRKWFEVAFV----LEERRPCDLP---AFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQKTVTLDVDVNNRSDRAEWCSCYYQGNFSLNSAFEIKLHWMAVTAAVLFEMVQGWHRKAASCGFLLVPVLEVPFALPSYLYGDPLRAQLFIPLNIQSL-------------LRDSSDSLFDGFEPETYWDRMQLFQEAILYRFGFVQD---KFSAS--AFNFPAENKPQ-----------------------YIHVTGTVFMQLP-YSKRK-------YSCGQQRRRRNSASSASQSLFGCEE-------RVGYNWAYNTMLTKAWRTG-VLGDEKLADRLLRDFTDFCSNKDNRLVAFW 1494

HSP 3 Score: 110.538 bits (275), Expect = 1.073e-23
Identity = 79/274 (28.83%), Postives = 128/274 (46.72%), Query Frame = 3

Query: 2196 IGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRK---PLGIHDVFQELIYQRLNQGFQMITNPPALNYSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKD-FMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQN--------SLIEEFFKFLEGIN 2981
            +GVDWKSLT PA LP+T+DY+P  + L++++ E  Y L+ ++                 PL I       I+ RL                           S  K +++ +++   +GR FH + +K  +I VT+Y P++      I Y+Y L  P ++  F+    +F  + LE++ WNY D YI + G      ++D   + LI SLKFWR+RF LLP   A         + +   D+Y D     ++        +L++ F +FLEG+N
Sbjct:  717 VGVDWKSLTTPACLPLTTDYFPDRQTLQNDYTEGCYDLLPHTDLDRYTHTYTGTHTAPVPLPIDLSIHPCIHSRL--------------------------VSRRKAEEEESLFWLSMGRTFHKVCLKDKIITVTRYLPKYPYESTQIQYSYSLCPPHAEGHFVPCWVEFGHERLEEYKWNYLDQYICSAG------SED---FSLIDSLKFWRTRFLLLPAGGA-----RRVADGEGHWDVYGDGPGAGRDGFGASGDWALLDGFIRFLEGLN 950

HSP 4 Score: 64.6994 bits (156), Expect = 9.559e-10
Identity = 26/57 (45.61%), Postives = 38/57 (66.67%), Query Frame = 3

Query: 1611 RKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKN 1781
            ++AL NPFAP+R  ++ TSN RRW H FP+    + IQ+HHQ   N  +L G E+++
Sbjct:  590 QRALINPFAPSRMPMKLTSNRRRWMHTFPVGPTGEAIQIHHQTRQNMAELQGSEQRD 646

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005893.1 (pep scaffold:Pmarinus_7.0:GL476980:101747:147917:1 gene:ENSPMAG00000005297.1 transcript:ENSPMAT00000005893.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 322.013 bits (824), Expect = 8.840e-90
Identity = 178/469 (37.95%), Postives = 290/469 (61.83%), Query Frame = 3

Query:   75 FHKKLKPEDDILFTAKDFSFISKGSLLEIYQQENDKHH--LIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYK--TELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRIC--DLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNIT-DNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFIYEIPENSLNFVRKLSKPEI 1457
            FH+ +  +++++   K F  +  G +LEI   +++     L+++ ++  +  QK+T+S D  +    KL   + +   V+  + +TLD+L++  +DQY+SRSDM+R    + ++   +++K++F G  R   SE+W  G++   G+   +TRVVFRS +++V+IFIQM  EMW+F+  G+LYF+KA+N F++DLF KW++ NC H++T+VLFSR +Y   ++++  + +  +I+ D  GRFYEDFY VV QNER   ++W  ++ T+K  F  Y     L+   +  F      +++ S+A   N+LE++N++ N+++ +YI+RNF+RTG++ VVIT G GV+ VDR    +TKQR+   DLG+G+DLVC+GEQPLHAVPLF    +SS + +  + Y IP+WINHSFY S N         F PRIK++     + E   +   D  F    PEN+  F  K S+  +
Sbjct:   12 FHESV--DEEVVVNPKVFPNVKIGDILEIAHPDDEYRSPLLLQVKSLKED-LQKETVSVDQSVAGVFKLRAYQDVFVNVVEPSDVTLDLLELTFKDQYISRSDMWRLKKSLVSTCAYITQKVEFAG-IRAQASELWVKGEKVTCGFISEDTRVVFRSTSAMVYIFIQMCCEMWDFNISGDLYFEKAVNGFLTDLFTKWKDKNCSHEVTVVLFSRTYYEAKSKDDFPEALNCHIQQDFRGRFYEDFYRVVAQNER--RDDWMSLLVTIKKIFIQYPRLVRLKTVGKLGFP-----KAHNSTAAQGNYLESINLSFNVFDKHYINRNFDRTGQMTVVITPGVGVFEVDRQLMILTKQRMIDNDLGIGVDLVCMGEQPLHAVPLFKLHNRSSKDGSVGDDYNIPHWINHSFYTSKN---LSYCASFTPRIKLA--PKHIAEITLECSGDQQF----PENAKEFSCKESETSL 460

HSP 2 Score: 134.42 bits (337), Expect = 1.288e-31
Identity = 87/266 (32.71%), Postives = 136/266 (51.13%), Query Frame = 3

Query: 2196 IGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNPPA--LNYSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDS-KDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYD-DKSVVEQNSLIEEFFKFLEGIN 2981
            +GVDWKSLT PA LP+T+DY+P  + L++++ E  Y L+ ++ +++        R  L    V++E I QRL QG+Q+I  P       S  ++                  +   +GR  H++ +K   I VT+Y P+H    A   Y Y L  P S  +F+    +F  + LE++ WNY D YI + G      ++D   + LI SLKFWR+RF LLP  +A    I   +     C+ Y+  +S  E+  LI+ F +F+E +N
Sbjct:  731 VGVDWKSLTTPACLPLTTDYFPDKQSLQNDYSEGCYDLLPDTFDADRSDEECVKR--LTTQQVYEEFISQRLMQGYQLIVQPRTRRAEISRNVYRPIKALVEEETH------HWLSMGRNLHMVSLKDKKISVTRYLPKHPYESAQFPYTYSLCTPHSDGEFLSCWVEFCHERLEEYKWNYLDQYICSAG------SED---FSLIESLKFWRTRFLLLPAATALTKRICEGEEP---CNSYEWQRSEDEELQLIDNFIRFMESLN 976

HSP 3 Score: 127.487 bits (319), Expect = 1.471e-29
Identity = 94/327 (28.75%), Postives = 141/327 (43.12%), Query Frame = 3

Query: 4128 HKNVLDYIGNSHDPGMLFE---KNGILYKKVVLDIE-SELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXX--XXXXXXXXXQLVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFY 5090
            H N+  ++  S  P  L +   +N      V L+++ +   +R EW    Y   Y  T AFE  +QW+VAT   L + +             LVP    PFALPS +  DPLR  +FVPLS+ CLI                 D LF  F  E  + R+ L QEAIL RFGFI++    YS+       + ++                          +IH +  +F++  ++         + LP  ++    +      R+  +     S     +GF W+ N MLT+ W +G    DE+F D++L DF EFC N DNRL  ++
Sbjct: 1176 HSNIPTFLLPSVLPADLTKTNIRNKTAIHTVTLEVDVNNRSDRLEWCSCYYHGQYSCTGAFELKLQWMVATAAVLFDMVQGWCRKATSCGFHLVPALDGPFALPSYLYGDPLRASLFVPLSVGCLITEGS-------------DHLFSAFDQETYMDRMHLFQEAILARFGFIQD---KYSAAAFNFPAESRS-------------------------QFIHVTEELFSLCVAF---------VQLPY-VKRKHPSGQQRRRRNSFSSTTPASLPEEKLGFCWAANGMLTKSWRSG-ATGDERFPDKLLRDFSEFCANKDNRLLHYW 1450

HSP 4 Score: 59.3066 bits (142), Expect = 8.654e-9
Identity = 25/64 (39.06%), Postives = 39/64 (60.94%), Query Frame = 3

Query: 1611 RKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKNSKNMAEA 1802
            ++AL NPFAP+R  ++ TSN RRW H FP+    +  Q+HHQ+   NP+    +  +S+   E+
Sbjct:  578 QRALINPFAPSRMPMKLTSNRRRWMHTFPVGPTGEAFQIHHQMR-PNPEELALQLVDSEEFTES 640

HSP 5 Score: 55.4546 bits (132), Expect = 1.521e-7
Identity = 28/79 (35.44%), Postives = 45/79 (56.96%), Query Frame = 3

Query: 3570 VLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFY 3806
            +L+ M +   G+ FL   +      F S EAVHW +S ++ + + + AV  LQK+++ + I HAS  +   F+YGF FY
Sbjct: 1060 ILDAMKHPNTGVQFLSEQKGLPTNCFISAEAVHWVMSTVEGMVNRQCAVDILQKMLDDQLISHASGDTLRAFIYGFYFY 1138

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Yeast
Match: IML1 (GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex; SEACIT (Iml1p-Npr2p-Npr3p) is a subcomplex of the SEA complex, a coatomer-related complex that associates dynamically with the vacuole; Iml1p functions in the SEACIT complex as a GAP for the Rag family GTPase Gtr1p (EGOC subunit), resulting in the inhibition of TORC1 signaling in response to amino acid deprivation; the Iml1p/SEACIT complex is required for non-nitrogen-starvation (NNS)-induced autophagy [Source:SGD;Acc:S000003899])

HSP 1 Score: 159.073 bits (401), Expect = 2.330e-39
Identity = 111/440 (25.23%), Postives = 213/440 (48.41%), Query Frame = 3

Query:   57 YECRLVFHKKLKPEDDILFTAKDFSFISKGSLLEI-------YQQENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLT---PNKSLKFQVMNENLITL--DVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKV 1337
            Y+  L +H+    E+ ++    +F  I  G L+E+            DK       + +   +++   S  S+L   L+     P++S  +  +  N   L  DV++  I+D  L+R DM+     + ++ + M ++L F    RGT+  ++ NG++  SGY G  TR++FRS ++ +   IQ++ EMW F+  GE  F K +N F   +F KW++ +  H +TI     +        +LSD   +++   E+ +  +D++ +VV     +   W  +++TL+  F   + +L   Q +     +N     S    +NFLE +N    +  + +   +   T    ++I+ GSG+++VD +   +T +++  L + MDL+C+ + PLH VPLF +R   +      H+ +P W++  F+   N+       ++ PR K+
Sbjct:  102 YQAELGYHESRFSENLVMLNLVEFPDIKPGDLVELKTYHKNPSASNGDKKIYFIAKDFDGETKRRAKTSNVSILSGQLQTLLDLPSRSRIWIKLKPNKFDLQADVVEFNIKDCLLNRGDMWVLSSKLVDTCVFMDQRLAFLDSIRGTIKGIYRNGKKIVSGYIGEQTRIIFRSESARLIFLIQITDEMWNFEETGEQLFQKMVNSFFPKIFKKWKDVDTHHTITIAFAISM--------DLSDTSFKDLTPGESLKNSQDYFRIVVDQVSII--HWVDIMETLREEFMEIRKDLLNKQTDKGYSVANGR--FSPVIKSNFLELVNFATTILTDPFKQLDLRHTTTHVMIISPGSGLFDVDYSLLRLTGKKLLSLEMTMDLICLSKAPLHIVPLFRYRDFENK----LHHCVPLWLSVFFW---NDHDKKSNSEWTPRCKI 522

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Nematostella
Match: EDO41898 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S342])

HSP 1 Score: 298.901 bits (764), Expect = 9.154e-90
Identity = 168/431 (38.98%), Postives = 255/431 (59.16%), Query Frame = 3

Query:   66 RLVFHKKLKPEDDILFTAKDFSFISKGSLLEIY---QQENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAIN-FISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQK---SSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKV 1337
            +L  H+    E++++   K+F    +G + EIY   +       L++I+N   + QQKDTIS    + N  +L     ++   ++   + +++ +I+I+DQYLSR+DM+R    + N+ + ++KK+   G  R  + E+W  G++   G    +TR+V+RS T+ V +FIQMS EMW+FD  G+LYF+K I+ F+ +LF KW+  N  H++TIVLFSR FY     E+     +  I  D   RFYEDFY VV+Q E+   ++W  V+ TLK  F  Y   +  +        + C S   +A D N LE  N+T+N++E +++DR F+RTG+  V++T G GV+ VDR+ T I KQR+ D GV  DLVC+ EQPLH+VPLF FR K      ++ D+ Y I +W+NHSFY S N     Q  +F+PRIKV
Sbjct:    7 KLWVHQHTFSENELIVNPKEFPDCKEGDVFEIYDPGEPVKAVRLLLQINNFIPDFQQKDTISILHSVANQFQLRTYWDVQVNKVDPKDVGIELAEILIKDQYLSRNDMWRLSKALDNTCVYVNKKVSSCG-IRCQIYELWTKGEKVSCGVINKDTRIVYRSLTAQVFLFIQMSQEMWDFDLNGDLYFEKTIHGFLYELFSKWKEQNATHEVTIVLFSRTFYDAKFIEDFPPERRPCILQDSYRRFYEDFYHVVIQREK--RDDWLPVLVTLKHHFTQYPKYINCYHDEP-GVPAGCNS---TAFDGNILEAYNLTMNIFEKHFVDRTFDRTGQTTVIVTPGPGVFEVDRSLTSIIKQRMVDSGVATDLVCMAEQPLHSVPLFKFRNKDLGQGVSLGDD-YNIAHWVNHSFYSSANA--KTQQDEFVPRIKV 427

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Nematostella
Match: EDO41899 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S344])

HSP 1 Score: 93.9745 bits (232), Expect = 2.519e-19
Identity = 92/320 (28.75%), Postives = 137/320 (42.81%), Query Frame = 3

Query: 4170 GMLFEKNGILYKKVVLDIESE-LGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQ--LVPVPCDPFALPSSINSDPLRGPIFVPLSIE-CLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFYLDVKTTAAK 5117
             ML  +    YK V LD + +   +R EW   +Y  NY+P  AFE  V W+ ATG  + + +  W++K +     LVP P  PF  PSS N DPLR PIF+PL++  C++              D  D LF + + ++  +   LL    L RFGF+++S         L NT     T       V C   A D        ++H SG  F  I  + +  D+   +  PV         SS       +            GF W  N ML+++W +     D +   ++ A+F EFC++T   L+ F+   K    K
Sbjct:  340 AMLMGECACAYKLVNLDCDPQHKSDRPEWCTLRYHGNYNPAHAFEMEVHWIEATGSIVHDMVQSWARKATSCGFVLVPAPVSPFPDPSSGNIDPLRLPIFIPLNLSGCIV--------------DERDSLFKDLALQKIFHSFHLLS---LGRFGFLKDSPYG-----PLFNTFTFVATP------VQCR--ADD--------FVHVSGTAFVRI--HDQDEDVRLDLYGPV---------SSGLLGERGS------------GFYWETNYMLSKRWRSA-STGDLESARKLQAEFVEFCSDTKGVLRAFWESCKDEVRK 597

HSP 2 Score: 66.6254 bits (161), Expect = 6.910e-11
Identity = 31/96 (32.29%), Postives = 51/96 (53.12%), Query Frame = 3

Query: 3531 ELDKLSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCN 3818
            E D LS  SP   +++ M++ + G+TFL S +  +   F + EAV W +  +D + D   AV   Q+++  + I HAS+ +   F YGF  +   N
Sbjct:  160 EGDVLSVKSPLEAIVDAMLDPKGGMTFLPSLKGLDSKCFLAIEAVWWLMHHVDGVADRNGAVALAQRMLEARVILHASKSTRQNFFYGFAIFQFAN 255

[Close]

BLAST of DEP domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000045034.1 (pep primary_assembly:ASM223467v1:17:6168060:6170188:1 gene:ENSORLG00000028003.1 transcript:ENSORLT00000045034.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.9214 bits (141), Expect = 1.241e-9
Identity = 33/130 (25.38%), Postives = 74/130 (56.92%), Query Frame = 3

Query:   66 RLVFHKKL--KPEDDILFTAKDFSFISKGSLLEIYQQEND-KHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGG 446
            +LV HKK     +D+++   K F  ++ G ++EI    ++    L+++ ++  +  QK+TIS D  +  + KL   + +   +++   +TLD++++  +DQY+ R DM+R    + ++   +++K++F G
Sbjct:    8 KLVLHKKGFGGSDDELVVNPKIFPQVNLGDVIEIAHPSDEYSPLLLQVKSLKED-LQKETISVDQTVAQAFKLRAYQDVIVNIVDPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYVTQKVEFAG 136

[Close]

BLAST of DEP domain-containing protein vs. Planmine SMEST
Match: SMESG000029435.1 (SMESG000029435.1)

HSP 1 Score: 3063.86 bits (7942), Expect = 0.000e+0
Identity = 1615/1699 (95.06%), Postives = 1622/1699 (95.47%), Query Frame = 3

Query:   48 MDIYECRLVFHKKLKPEDDILFTAKDFSFISKGSLLEIYQQENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAINFISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFIYEIPENSLNFVRKLSKPEIVSDNISGVISTSNNCERGGLYHGSYGSHNSKDDTFINPIKPGHKRIIQSDHRKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKNSKNMAEAWKNYYKLYTEANNKXXXXXXXXXXXXXXXXXXXPKSPFRETDDSSVIMEKAEFHIINDKISDDSIGVSLLPXXXXXXXXXXXXXXXXXIKGSINRRVHTLFTEGEQKWSWDQPKEDESPINHLDVEESIKLIGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNPPALNYSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRRSPNSKPKMSMPVIDNSSNLMNNPSMVKVKSVSGNLLEMKVSSSNMXXXXXXXXXXXXXXXXDKIDLLMLIQSYLIACEPSINSTLDNLVNVPSSGGSLNQHQKSAIQSACIVTNANPMSPSRPAVHHRHSTTHEPNHYNQLCELISNNSSNPVTPIEKYPRQFTFDSLENTMKSSSGLELDKLSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNIXXXXXXXXXXXXXXXDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIESELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQLVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFYLDVKTTAAKYFCDKTSHV 5144
            MDIYECRLVFHKKLKPEDDILFTAKDFSFISKGSLLEIYQQENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAINFISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFIYEIPENSLNFVRKLSKPEIVSDNISGVISTSNNCERGGLYHGSYGSHNSKDDTFINPIKPGHKRIIQSDHRKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKNSKNMAEAWKNYYKLYTEANNKSDQSDESTSSLSTRETILTPKSPFRETDDSSVIMEKAEFHIINDKISDDSIGVSLLPSSFQGGGSQKSFHQSSSIKGSINRRVHTLFTEGEQKWSWDQPKEDESPINHLDVEESIKLIGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMANSSNSNSEMNNQSHRKPLGIHDVFQELIYQRLNQGFQMITNPPALNYSSTIFSKDVNKKSSSKIKDKNAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSATKTIIDTDKNKKIRCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRRSPNSKPKMSMPVIDNSSNLMNNPSMVKVKSVSGNLLEMK S+                           IQS   AC                            + +A  ++ + P    R +  H      EPNHYNQLCELISNNSSNPVTPIEKYPRQFTFDSLENTMKSSSGLELDKLSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNISNANSSSSSLTNLATDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIESELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEKISLWSKKKSILQLVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFYLDVKTTAAKYFCDKTSHV
Sbjct:    1 MDIYECRLVFHKKLKPEDDILFTAKDFSFISKGSLLEIYQQENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAINFISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFIYEIPENSLNFVRKLSKPEIVSDNISGVISTSNNCERGGLYHGSYGSHNSKDDTFINPIKPGHKRIIQSDHRKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKNSKNMAEAWKNYYKLYTEANNKSDQSDESTSSLSTRETILTPKSPFRETDDSSVIMEKAEFHIINDKISDDSIGVSLLPSSFQGGGSQKSFHQSSSIKGSINRRVHTLFTEGEQKWSWDQPKEDESPINHLDVEESIKLIGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMANSSNSNSEMNNQSHRKPLGIHDVFQELIYQRLNQGFQMITNPPALNYSSTIFSKDVNKKSSSKIKDKNAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSATKTIIDTDKNKKIRCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRRSPNSKPKMSMPVIDNSSNLMNNPSMVKVKSVSGNLLEMKKSA---------------------------IQS---AC---------------------------IVTNANPMSPSRPAVHHRHSTTH------EPNHYNQLCELISNNSSNPVTPIEKYPRQFTFDSLENTMKSSSGLELDKLSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNISNANSSSSSLTNLATDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIESELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEKISLWSKKKSILQLVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFYLDVKTTAAKYFCDKTSHV 1636

[Close]

BLAST of DEP domain-containing protein vs. Planmine SMEST
Match: SMESG000029435.1 (SMESG000029435.1)

HSP 1 Score: 3039.21 bits (7878), Expect = 0.000e+0
Identity = 1606/1699 (94.53%), Postives = 1613/1699 (94.94%), Query Frame = 3

Query:   48 MDIYECRLVFHKKLKPEDDILFTAKDFSFISKGSLLEIYQQENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAINFISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFIYEIPENSLNFVRKLSKPEIVSDNISGVISTSNNCERGGLYHGSYGSHNSKDDTFINPIKPGHKRIIQSDHRKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKNSKNMAEAWKNYYKLYTEANNKXXXXXXXXXXXXXXXXXXXPKSPFRETDDSSVIMEKAEFHIINDKISDDSIGVSLLPXXXXXXXXXXXXXXXXXIKGSINRRVHTLFTEGEQKWSWDQPKEDESPINHLDVEESIKLIGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNPPALNYSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRRSPNSKPKMSMPVIDNSSNLMNNPSMVKVKSVSGNLLEMKVSSSNMXXXXXXXXXXXXXXXXDKIDLLMLIQSYLIACEPSINSTLDNLVNVPSSGGSLNQHQKSAIQSACIVTNANPMSPSRPAVHHRHSTTHEPNHYNQLCELISNNSSNPVTPIEKYPRQFTFDSLENTMKSSSGLELDKLSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNIXXXXXXXXXXXXXXXDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIESELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQLVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFYLDVKTTAAKYFCDKTSHV 5144
            MDIYECRLVFHKKLKPEDDILFTAKDFSFISKGSLLEIYQQENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAINFISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFIYEIPENSLNFVRKLSKPEIVSDNISGVISTSNNCERGGLYHGSYGSHNSKDDTFINPIKPGHKRIIQSDHRKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKNSKNMAEAWKNYYKLYTEANNKSDQSDESTSSLSTRETILTPKSPFRETDDSSVIMEKAEFHIINDKISDDSIGVSLLPSSFQGGGSQKSFHQSSSIKGSINRRVHTLFTEGEQKWSWDQPKEDESPINHL         GVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMANSSNSNSEMNNQSHRKPLGIHDVFQELIYQRLNQGFQMITNPPALNYSSTIFSKDVNKKSSSKIKDKNAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSATKTIIDTDKNKKIRCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRRSPNSKPKMSMPVIDNSSNLMNNPSMVKVKSVSGNLLEMK S+                           IQS   AC                            + +A  ++ + P    R +  H      EPNHYNQLCELISNNSSNPVTPIEKYPRQFTFDSLENTMKSSSGLELDKLSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNISNANSSSSSLTNLATDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIESELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEKISLWSKKKSILQLVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFYLDVKTTAAKYFCDKTSHV
Sbjct:    1 MDIYECRLVFHKKLKPEDDILFTAKDFSFISKGSLLEIYQQENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAINFISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFIYEIPENSLNFVRKLSKPEIVSDNISGVISTSNNCERGGLYHGSYGSHNSKDDTFINPIKPGHKRIIQSDHRKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKNSKNMAEAWKNYYKLYTEANNKSDQSDESTSSLSTRETILTPKSPFRETDDSSVIMEKAEFHIINDKISDDSIGVSLLPSSFQGGGSQKSFHQSSSIKGSINRRVHTLFTEGEQKWSWDQPKEDESPINHL---------GVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMANSSNSNSEMNNQSHRKPLGIHDVFQELIYQRLNQGFQMITNPPALNYSSTIFSKDVNKKSSSKIKDKNAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSATKTIIDTDKNKKIRCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRRSPNSKPKMSMPVIDNSSNLMNNPSMVKVKSVSGNLLEMKKSA---------------------------IQS---AC---------------------------IVTNANPMSPSRPAVHHRHSTTH------EPNHYNQLCELISNNSSNPVTPIEKYPRQFTFDSLENTMKSSSGLELDKLSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNISNANSSSSSLTNLATDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIESELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEKISLWSKKKSILQLVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFYLDVKTTAAKYFCDKTSHV 1627

[Close]

BLAST of DEP domain-containing protein vs. Planmine SMEST
Match: SMESG000029435.1 (SMESG000029435.1)

HSP 1 Score: 1935.61 bits (5013), Expect = 0.000e+0
Identity = 1022/1024 (99.80%), Postives = 1023/1024 (99.90%), Query Frame = 3

Query:   48 MDIYECRLVFHKKLKPEDDILFTAKDFSFISKGSLLEIYQQENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAINFISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFIYEIPENSLNFVRKLSKPEIVSDNISGVISTSNNCERGGLYHGSYGSHNSKDDTFINPIKPGHKRIIQSDHRKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKNSKNMAEAWKNYYKLYTEANNKXXXXXXXXXXXXXXXXXXXPKSPFRETDDSSVIMEKAEFHIINDKISDDSIGVSLLPXXXXXXXXXXXXXXXXXIKGSINRRVHTLFTEGEQKWSWDQPKEDESPINHLDVEESIKLIGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMAXXXXXXXXXXXXXHRKPLGIHDVFQELIYQRLNQGFQMITNPPALNYSSTIFXXXXXXXXXXXXXXXXAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSAXXXXXXXXXXXXXRCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRRSPNSKPKMSMPVIDNSSNLMNNPSMVKVKSVSGNLLEMKVS 3119
            MDIYECRLVFHKKLKPEDDILFTAKDFSFISKGSLLEIYQQENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAINFISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFIYEIPENSLNFVRKLSKPEIVSDNISGVISTSNNCERGGLYHGSYGSHNSKDDTFINPIKPGHKRIIQSDHRKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKNSKNMAEAWKNYYKLYTEANNKSDQSDESTSSLSTRETILTPKSPFRETDDSSVIMEKAEFHIINDKISDDSIGVSLLPSSFQGGGSQKSFHQSSSIKGSINRRVHTLFTEGEQKWSWDQPKEDESPINHLDVEESIKLIGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMANSSNSNSEMNNQSHRKPLGIHDVFQELIYQRLNQGFQMITNPPALNYSSTIFSKDVNKKSSSKIKDKNAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSATKTIIDTDKNKKIRCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRRSPNSKPKMSMPVIDNSSNLMNNPSMVKVKSVSGNLLEMK +
Sbjct:    1 MDIYECRLVFHKKLKPEDDILFTAKDFSFISKGSLLEIYQQENDKHHLIKIDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDIIIRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNHSGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAINFISDLFLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYEDFYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCESYLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVDRAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYYIPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNFIYEIPENSLNFVRKLSKPEIVSDNISGVISTSNNCERGGLYHGSYGSHNSKDDTFINPIKPGHKRIIQSDHRKALFNPFAPNRFNVRTTSNSRRWSHVFPIDKNNKPIQLHHQLAINNPDLYGFEKKNSKNMAEAWKNYYKLYTEANNKSDQSDESTSSLSTRETILTPKSPFRETDDSSVIMEKAEFHIINDKISDDSIGVSLLPSSFQGGGSQKSFHQSSSIKGSINRRVHTLFTEGEQKWSWDQPKEDESPINHLDVEESIKLIGVDWKSLTLPAMLPITSDYYPSARILEDEFLESNYQLMANSSNSNSEMNNQSHRKPLGIHDVFQELIYQRLNQGFQMITNPPALNYSSTIFSKDVNKKSSSKIKDKNAIYKFGLGRIFHIIQMKQDLIHVTQYSPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYILNYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSATKTIIDTDKNKKIRCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRRSPNSKPKMSMPVIDNSSNLMNNPSMVKVKSVSGNLLEMKFT 1024

HSP 2 Score: 1096.65 bits (2835), Expect = 0.000e+0
Identity = 554/555 (99.82%), Postives = 555/555 (100.00%), Query Frame = 3

Query: 3480 QFTFDSLENTMKSSSGLELDKLSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNIXXXXXXXXXXXXXXXDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIESELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEXXXXXXXXXXXXQLVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFYLDVKTTAAKYFCDKTSHV 5144
            +FTFDSLENTMKSSSGLELDKLSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNISNANSSSSSLTNLATDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIESELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEKISLWSKKKSILQLVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFYLDVKTTAAKYFCDKTSHV
Sbjct: 1022 KFTFDSLENTMKSSSGLELDKLSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTFTSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGFVFYCLCNPTKFLGNGWLDVRNISNANSSSSSLTNLATDESDNFIKSKNNIEWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDIPEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIESELGERAEWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEKISLWSKKKSILQLVPVPCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFLFDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTKNVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITLPVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTGPMVIDEQFQDRMLADFREFCTNTDNRLKQFYLDVKTTAAKYFCDKTSHV 1576

The following BLAST results are available for this feature:

BLAST of DEP domain-containing protein vs. Ensembl Human
BLAST of DEP domain-containing protein vs. Ensembl Celegans
BLAST of DEP domain-containing protein vs. Ensembl Fly
BLAST of DEP domain-containing protein vs. Ensembl Zebrafish
BLAST of DEP domain-containing protein vs. Ensembl Xenopus
BLAST of DEP domain-containing protein vs. Ensembl Mouse
BLAST of DEP domain-containing protein vs. UniProt/SwissProt
BLAST of DEP domain-containing protein vs. TrEMBL
BLAST of DEP domain-containing protein vs. Ensembl Cavefish
BLAST of DEP domain-containing protein vs. Ensembl Sea Lamprey
BLAST of DEP domain-containing protein vs. Ensembl Yeast
BLAST of DEP domain-containing protein vs. Ensembl Nematostella
BLAST of DEP domain-containing protein vs. Ensembl Medaka
BLAST of DEP domain-containing protein vs. Planmine SMEST

BLAST of DEP domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
DEPDC5	4.121e-100	40.64	DEP domain containing 5, GATOR1 subcomplex subunit...	[more]
DEPDC5	4.121e-100	40.64	DEP domain containing 5, GATOR1 subcomplex subunit...	[more]
DEPDC5	2.067e-99	40.64	DEP domain containing 5, GATOR1 subcomplex subunit...	[more]
DEPDC5	2.067e-99	40.64	DEP domain containing 5, GATOR1 subcomplex subunit...	[more]
DEPDC5	2.423e-98	39.57	DEP domain containing 5, GATOR1 subcomplex subunit...	[more]

BLAST of DEP domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
T08A11.1	3.182e-63	36.22	pep chromosome:WBcel235:III:4248155:4263048:-1 gen...	[more]

BLAST of DEP domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Iml1	1.837e-94	42.45	gene:FBgn0035227 transcript:FBtr0333402	[more]
Iml1	2.099e-94	42.45	gene:FBgn0035227 transcript:FBtr0333401	[more]
Iml1	2.262e-94	42.45	gene:FBgn0035227 transcript:FBtr0072704	[more]
Iml1	2.336e-94	42.45	gene:FBgn0035227 transcript:FBtr0072703	[more]
Iml1	2.560e-94	42.45	gene:FBgn0035227 transcript:FBtr0072705	[more]

BLAST of DEP domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
depdc5	1.823e-95	39.52	DEP domain containing 5, GATOR1 subcomplex subunit...	[more]
depdc5	2.189e-95	39.52	DEP domain containing 5, GATOR1 subcomplex subunit...	[more]
depdc5	8.559e-16	33.33	DEP domain containing 5, GATOR1 subcomplex subunit...	[more]

BLAST of DEP domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSXETT00000047719.1	3.053e-97	34.76	DEP domain containing 5 [Source:NCBI gene;Acc:1004...	[more]
ENSXETT00000047756.1	2.989e-93	34.58	DEP domain containing 5 [Source:NCBI gene;Acc:1004...	[more]
ENSXETT00000047660.1	2.054e-92	33.59	DEP domain containing 5 [Source:NCBI gene;Acc:1004...	[more]
ENSXETT00000047706.1	5.135e-92	34.07	DEP domain containing 5 [Source:NCBI gene;Acc:1004...	[more]
ENSXETT00000047348.1	6.883e-92	33.80	DEP domain containing 5 [Source:NCBI gene;Acc:1004...	[more]

BLAST of DEP domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Depdc5	2.342e-96	40.13	DEP domain containing 5 [Source:MGI Symbol;Acc:MGI...	[more]
Depdc5	2.788e-94	40.13	DEP domain containing 5 [Source:MGI Symbol;Acc:MGI...	[more]
Depdc5	1.161e-93	40.13	DEP domain containing 5 [Source:MGI Symbol;Acc:MGI...	[more]
Depdc5	1.224e-93	40.13	DEP domain containing 5 [Source:MGI Symbol;Acc:MGI...	[more]
Depdc5	1.134e-36	26.87	DEP domain containing 5 [Source:MGI Symbol;Acc:MGI...	[more]

BLAST of DEP domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9W0E3\|IML1_DROME	2.341e-93	42.45	GATOR complex protein Iml1 OS=Drosophila melanogas...	[more]
sp\|O75140\|DEPD5_HUMAN	7.346e-93	39.57	GATOR complex protein DEPDC5 OS=Homo sapiens OX=96...	[more]
sp\|P61460\|DEPD5_MOUSE	8.560e-93	40.13	GATOR complex protein DEPDC5 OS=Mus musculus OX=10...	[more]
sp\|Q54XA2\|Y9099_DICDI	1.548e-60	35.60	DEP domain-containing protein DDB_G0279099 OS=Dict...	[more]
sp\|Q4PE51\|IML1_USTMA	2.814e-50	31.34	Vacuolar membrane-associated protein IML1 OS=Ustil...	[more]

BLAST of DEP domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A132AEU0	4.924e-128	33.43	DUF3608 domain-containing protein OS=Sarcoptes sca...	[more]
A0A2T7PE36	8.499e-123	38.67	Uncharacterized protein OS=Pomacea canaliculata OX...	[more]
A0A0L8FG79	9.918e-117	38.05	Uncharacterized protein OS=Octopus bimaculoides OX...	[more]
A0A0L8FG47	3.113e-113	37.36	Uncharacterized protein OS=Octopus bimaculoides OX...	[more]
A0A1S3HEX7	7.888e-110	39.46	GATOR complex protein DEPDC5 OS=Lingula unguis OX=...	[more]

BLAST of DEP domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
depdc5	8.575e-91	39.22	DEP domain containing 5, GATOR1 subcomplex subunit...	[more]
depdc5	8.914e-91	39.22	DEP domain containing 5, GATOR1 subcomplex subunit...	[more]

BLAST of DEP domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000005893.1	8.840e-90	37.95	pep scaffold:Pmarinus_7.0:GL476980:101747:147917:1...	[more]

BLAST of DEP domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
IML1	2.330e-39	25.23	GTPase-activating protein (GAP) subunit of the Iml...	[more]

BLAST of DEP domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO41898	9.154e-90	38.98	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41899	2.519e-19	28.75	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of DEP domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSORLT00000045034.1	1.241e-9	25.38	pep primary_assembly:ASM223467v1:17:6168060:617018...	[more]

BLAST of DEP domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3


Match Name	E-value	Identity	Description
SMESG000029435.1	0.000e+0	95.06	SMESG000029435.1	[more]
SMESG000029435.1	0.000e+0	94.53	SMESG000029435.1	[more]
SMESG000029435.1	0.000e+0	99.80	SMESG000029435.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30010473 ID=SMED30010473|Name=DEP domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=5196bp
ATATTCTTCATTGAATGCGATAGATTAAATATTTTAGGTGATTTTGAATG
GATATTTATGAGTGTCGATTAGTATTTCATAAAAAGCTTAAACCAGAAGA
TGATATACTGTTTACCGCGAAAGACTTTTCATTTATCTCAAAAGGGTCTT
TGTTGGAAATATACCAACAAGAAAATGATAAACACCATTTAATAAAAATT
GACAATGTTAATTCAAATCCTCAACAAAAGGACACTATTAGTTTTGATAG
TGTCCTTGGTAATAGTTTAAAATTAACTCCGAATAAGTCATTAAAATTTC
AAGTTATGAATGAAAATTTAATCACACTTGATGTTTTGGATATTATCATT
CGTGATCAATATCTTAGCAGAAGTGATATGTATAGATTTATTCATCACAT
ACAAAATTCTGTTCTTCAAATGTCGAAAAAACTGGATTTTGGTGGGTATT
TTAGGGGAACAGTTAGTGAAATGTGGTGTAACGGCCAGAGAAATCACAGT
GGATATTTTGGCGCCAACACGAGGGTGGTTTTTCGATCTGCCACTTCTGT
TGTGCACATTTTCATTCAAATGAGCACTGAAATGTGGGAATTTGATTATT
TTGGGGAATTGTATTTCGATAAAGCAATTAACTTCATTTCAGACTTGTTC
CTCAAATGGCAAAATTACAATTGCGGACATGACATGACTATTGTACTATT
TAGTAGATTGTTTTATAGGAATTTGAATCAAGAAAACCTTTCAGATAATG
TTAAACGGAACATAAAAATAGACGAAAATGGGAGATTCTATGAAGATTTT
TACATCGTTGTTGTTCAAAATGAGCGCTATGTCGGAAATGAATGGCGGAA
AGTGATCAAAACTCTGAAATTTCGATTTAATAACTATAAAACTGAACTCG
AGCAATTTCAACAGAACAATTTCGATTGCAACAGTAATTGCGAGAGTTAT
CTGTCATCGGCGGAAGACGCAAACTTCCTTGAGACATTGAATATCACATT
AAACTTGTATGAGAATTACTATATCGATCGGAATTTTGAGAGAACTGGAA
AGGTTTGCGTCGTGATTACGGCAGGATCAGGAGTTTATAATGTTGATCGA
GCCCAAACTCATATTACAAAGCAGAGGATTTGCGATTTGGGTGTTGGCAT
GGATCTCGTATGTATTGGAGAACAGCCGTTACACGCCGTTCCATTATTTA
TATTCCGACAAAAAAGTTCTTCAAATATAACAGATAACCATTATTATATT
CCCTATTGGATAAATCACAGTTTCTATCGGTCTGTAAATGAGCTTCAAGC
CATTCAAATGGGTAAATTTATACCAAGAATTAAAGTATCTTTTGAAAAGA
GTTCTTTGATAGAAAAATTAGCTAAACCAAAAGATGATAATAATTTTATT
TACGAAATACCAGAAAATTCATTGAATTTCGTCAGGAAGTTATCGAAACC
AGAAATTGTAAGTGATAATATTTCGGGTGTGATTTCCACATCCAATAATT
GTGAGCGAGGTGGTTTGTATCATGGAAGTTATGGTAGTCACAATAGTAAA
GATGATACTTTTATCAATCCTATTAAACCGGGACACAAACGAATTATTCA
ATCAGACCACAGAAAGGCTCTTTTCAATCCTTTTGCTCCTAATAGATTTA
ATGTCCGCACCACATCTAACAGTCGTCGATGGTCTCACGTTTTCCCAATT
GATAAAAATAATAAACCGATTCAATTACATCATCAATTAGCCATTAATAA
TCCTGATTTATATGGATTCGAAAAGAAAAATTCAAAAAATATGGCTGAAG
CTTGGAAAAATTATTATAAACTGTATACTGAGGCCAATAATAAATCTGAT
CAGTCTGATGAATCTACATCTAGCTTATCTACTCGAGAAACTATCCTAAC
GCCTAAAAGTCCATTTCGTGAGACGGACGATTCAAGTGTAATAATGGAAA
AAGCTGAATTTCATATTATCAATGACAAGATTAGTGATGATTCTATTGGA
GTCAGCCTTTTGCCAAGCTCATTTCAAGGGGGAGGCAGTCAAAAATCCTT
TCATCAAAGCTCGTCAATAAAAGGGTCCATAAACCGTCGCGTTCATACAT
TATTTACCGAAGGGGAACAGAAATGGAGTTGGGATCAACCGAAAGAAGAT
GAAAGTCCTATAAATCATTTGGATGTTGAAGAATCTATCAAACTCATTGG
AGTCGACTGGAAATCTTTGACTTTACCTGCAATGTTGCCTATTACCTCTG
ATTATTATCCGAGCGCCAGAATCCTCGAGGATGAATTTTTGGAATCGAAC
TATCAATTAATGGCTAACAGTTCGAATAGTAACAGTGAAATGAATAATCA
ATCTCACAGAAAACCTCTAGGGATTCATGATGTTTTCCAAGAGCTGATTT
ATCAGCGATTAAATCAGGGATTTCAAATGATTACAAATCCCCCGGCTTTG
AATTACTCATCTACCATCTTTTCTAAGGATGTTAATAAAAAAAGTTCTTC
TAAAATCAAGGATAAAAATGCCATTTATAAATTCGGACTTGGTCGCATTT
TTCACATTATTCAAATGAAGCAGGATCTCATCCATGTTACGCAATATAGT
CCACGACATACGAATAATTTGGCTGATATTACTTATAATTATTGTCTGAA
AATGCCAGACTCCAAAGACTTCATGATGTCCAAAACAAAATTCTCTACTC
AAATGCTAGAAAAGTTCAATTGGAATTATCATGATCATTACATTCTGAAT
TACGGGGGAAATATCAATGAAAGCACTGATGATATTTGTCGCTACAAATT
AATTCCGTCTCTAAAGTTTTGGCGTAGCAGATTTTATTTGCTGCCAACAC
ATTCGGCCACTAAAACCATAATCGATACGGATAAAAACAAAAAGATTCGA
TGCGACATATATGATGATAAATCAGTTGTGGAACAGAATTCACTGATTGA
AGAATTTTTCAAATTTCTCGAAGGTATTAACAAAATAAAAAGACGATCTC
CCAATTCTAAGCCGAAAATGTCGATGCCCGTCATTGATAATTCATCAAAT
TTGATGAACAATCCCAGCATGGTGAAAGTGAAATCCGTCAGCGGTAATCT
ATTAGAAATGAAAGTAAGCTCATCAAATATGCTATGTTTATTGTTGAAAA
TTTTACTGTTAATTATGCGCTCTTTGATTGATAAAATTGATTTGCTTATG
CTTATCCAGTCTTATTTAATTGCGTGTGAACCTTCCATAAACTCAACCTT
GGACAATTTAGTCAATGTTCCTAGTAGTGGGGGTTCATTAAATCAACATC
AGAAATCAGCCATTCAATCGGCATGCATAGTCACGAATGCAAACCCAATG
TCTCCGAGTAGACCAGCGGTTCACCATCGGCATTCTACAACTCACGAACC
TAATCATTACAATCAACTCTGTGAACTCATTTCCAACAATAGTTCCAATC
CGGTAACACCGATAGAAAAGTATCCGCGTCAGTTCACGTTTGACTCGCTA
GAAAATACTATGAAATCTTCAAGTGGTTTAGAATTGGATAAGCTTAGTGA
TTCCTCACCTTATGTTAGAGTTTTAGAAGAAATGATGAATTCTCAAAATG
GTTTGACATTTTTACAATCTCCGGAATTTCCTAATGAATATACGTTCACC
TCATACGAAGCTGTCCATTGGTGCATCAGTAAATTGGACAAAATTACTGA
CGTCAAATCAGCTGTAGTATATCTACAGAAATTAATGAATTTAAAATATA
TATTTCATGCGTCGGAGTATTCTTCTCATAAATTTGTCTACGGATTTGTG
TTCTATTGTTTGTGTAATCCAACAAAATTTCTAGGAAATGGCTGGTTAGA
TGTGCGAAATATTAGCAATGCCAATAGCAGTAGTAGCTCGCTCACAAATT
TGGCTACCGATGAATCAGATAACTTTATTAAATCCAAGAATAATATTGAA
TGGGTGGAAGTGTATTTATGTTCAATGGAAATTGATGGAAAACCCGAACG
AGATTATTTAGAGAGATCGTTCCTCGGATTTCATTTGCCTGGTGATTATA
AGCCTGTTGATTCTTCCAATAATTTCATATTTCTGATGAAAGACATACCG
GAAAAATATCTCATTAATTGTTTAACTCATAAAAATGTTCTCGACTATAT
TGGTAATTCTCATGATCCCGGAATGCTATTTGAGAAAAATGGAATTTTAT
ATAAGAAAGTCGTTTTGGATATTGAAAGTGAACTGGGTGAACGAGCTGAG
TGGGGCGTGTTTCAGTATCAAGCTAACTACCATCCGACTATGGCGTTTGA
ATTTATGGTACAATGGTTGGTAGCTACCGGTGGTAAATTGGCAGAAAAAA
TTAGTCTATGGAGTAAGAAAAAGTCCATTCTTCAATTAGTTCCTGTTCCT
TGTGACCCATTTGCACTTCCCAGTTCTATCAATTCAGATCCTTTGCGTGG
ACCAATTTTTGTACCCCTGAGTATTGAATGTTTGATAGAGAATGCAGATT
ATTTCAAATCATCTCACCGTTCTATTAATGATACGATTGATTTCTTATTT
GATGAATTTTCAGATGAAGAGAGACTATATAGATTAATGTTATTGCAAGA
AGCTATTTTGAAAAGATTTGGTTTTATTCGTGAATCATGTATAAACTACT
CATCCAAAGATCATTTGTTAAATACTCAAATTAAAAATACCACAAAAAAT
GTAGAAGGAAAACAAGTGTATTGTGATTCATTGGCAACTGATGGCTGTAC
CTCTTTAACTTGGTCATATATACATTACAGTGGAGGAATGTTCGCAATGA
TTCCTTCCTATAGTAAATATAGGGATATCAACGATCTGATCACTCTGCCA
GTAAAGATTGAAGAGACCCAATCTAATTTATCTAGTTCATACACCAGACA
TGTTAATACAGACGAAGATTCAGATAGCTGGGAAACTGTTAACATTGGTT
TTCTTTGGTCTTGGAATAAAATGTTGACTCGAAAATGGACAACTGGTCCC
ATGGTTATTGACGAGCAATTCCAGGATCGAATGCTGGCTGACTTTCGTGA
ATTTTGCACCAACACCGACAATCGACTGAAACAATTTTATTTGGATGTCA
AAACGACCGCCGCAAAATATTTCTGTGATAAAACTTCACATGTTTAAATT
ATGAACTTTTTGATGCAATTTCTATTAAAATAAATCTTATTTTTGT

protein sequence of SMED30010473-orf-1

>SMED30010473-orf-1 ID=SMED30010473-orf-1|Name=SMED30010473-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1700bp
MDIYECRLVFHKKLKPEDDILFTAKDFSFISKGSLLEIYQQENDKHHLIK
IDNVNSNPQQKDTISFDSVLGNSLKLTPNKSLKFQVMNENLITLDVLDII
IRDQYLSRSDMYRFIHHIQNSVLQMSKKLDFGGYFRGTVSEMWCNGQRNH
SGYFGANTRVVFRSATSVVHIFIQMSTEMWEFDYFGELYFDKAINFISDL
FLKWQNYNCGHDMTIVLFSRLFYRNLNQENLSDNVKRNIKIDENGRFYED
FYIVVVQNERYVGNEWRKVIKTLKFRFNNYKTELEQFQQNNFDCNSNCES
YLSSAEDANFLETLNITLNLYENYYIDRNFERTGKVCVVITAGSGVYNVD
RAQTHITKQRICDLGVGMDLVCIGEQPLHAVPLFIFRQKSSSNITDNHYY
IPYWINHSFYRSVNELQAIQMGKFIPRIKVSFEKSSLIEKLAKPKDDNNF
IYEIPENSLNFVRKLSKPEIVSDNISGVISTSNNCERGGLYHGSYGSHNS
KDDTFINPIKPGHKRIIQSDHRKALFNPFAPNRFNVRTTSNSRRWSHVFP
IDKNNKPIQLHHQLAINNPDLYGFEKKNSKNMAEAWKNYYKLYTEANNKS
DQSDESTSSLSTRETILTPKSPFRETDDSSVIMEKAEFHIINDKISDDSI
GVSLLPSSFQGGGSQKSFHQSSSIKGSINRRVHTLFTEGEQKWSWDQPKE
DESPINHLDVEESIKLIGVDWKSLTLPAMLPITSDYYPSARILEDEFLES
NYQLMANSSNSNSEMNNQSHRKPLGIHDVFQELIYQRLNQGFQMITNPPA
LNYSSTIFSKDVNKKSSSKIKDKNAIYKFGLGRIFHIIQMKQDLIHVTQY
SPRHTNNLADITYNYCLKMPDSKDFMMSKTKFSTQMLEKFNWNYHDHYIL
NYGGNINESTDDICRYKLIPSLKFWRSRFYLLPTHSATKTIIDTDKNKKI
RCDIYDDKSVVEQNSLIEEFFKFLEGINKIKRRSPNSKPKMSMPVIDNSS
NLMNNPSMVKVKSVSGNLLEMKVSSSNMLCLLLKILLLIMRSLIDKIDLL
MLIQSYLIACEPSINSTLDNLVNVPSSGGSLNQHQKSAIQSACIVTNANP
MSPSRPAVHHRHSTTHEPNHYNQLCELISNNSSNPVTPIEKYPRQFTFDS
LENTMKSSSGLELDKLSDSSPYVRVLEEMMNSQNGLTFLQSPEFPNEYTF
TSYEAVHWCISKLDKITDVKSAVVYLQKLMNLKYIFHASEYSSHKFVYGF
VFYCLCNPTKFLGNGWLDVRNISNANSSSSSLTNLATDESDNFIKSKNNI
EWVEVYLCSMEIDGKPERDYLERSFLGFHLPGDYKPVDSSNNFIFLMKDI
PEKYLINCLTHKNVLDYIGNSHDPGMLFEKNGILYKKVVLDIESELGERA
EWGVFQYQANYHPTMAFEFMVQWLVATGGKLAEKISLWSKKKSILQLVPV
PCDPFALPSSINSDPLRGPIFVPLSIECLIENADYFKSSHRSINDTIDFL
FDEFSDEERLYRLMLLQEAILKRFGFIRESCINYSSKDHLLNTQIKNTTK
NVEGKQVYCDSLATDGCTSLTWSYIHYSGGMFAMIPSYSKYRDINDLITL
PVKIEETQSNLSSSYTRHVNTDEDSDSWETVNIGFLWSWNKMLTRKWTTG
PMVIDEQFQDRMLADFREFCTNTDNRLKQFYLDVKTTAAKYFCDKTSHV*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0005096	GTPase activator activity

Vocabulary: **biological process**
Term	Definition
GO:0043547	positive regulation of GTPase activity
GO:0035556	intracellular signal transduction

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000070	intestinal phagocyte
PLANA:0000099	neuron
PLANA:0000101	muscle cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036388	WH-like_DNA-bd_sf
IPR036390	WH_DNA-bd_sf
IPR027244	IML1
IPR000591	DEP_dom
IPR011991	WHTH_DNA-bd_dom

Vocabulary: **cellular component**
Term	Definition
GO:0005773	vacuole
GO:0005774	vacuolar membrane
GO:0016020	membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 270..290
IPR027244	Vacuolar membrane-associated protein Iml1	PFAM	PF12257	IML1	coord: 98..386 e-value: 1.7E-93 score: 312.9
IPR027244	Vacuolar membrane-associated protein Iml1	PANTHER	PTHR13179	DEP DOMAIN CONTAINING PROTEIN 5	coord: 6..431 coord: 518..1689
IPR036388	Winged helix-like DNA-binding domain superfamily	GENE3D	G3DSA:1.10.10.10		coord: 1153..1256 e-value: 4.2E-7 score: 31.6
IPR000591	DEP domain	PROSITE	PS50186	DEP	coord: 1197..1257 score: 9.556
IPR036390	Winged helix DNA-binding domain superfamily	SUPERFAMILY	SSF46785	"Winged helix" DNA-binding domain	coord: 1198..1292