Cathepsin B

Overview
NameCathepsin B
Smed IDSMED30010459
Length (bp)1266
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cathepsin B (SMED30010459) t-SNE clustered cells

Violin plots show distribution of expression levels for Cathepsin B (SMED30010459) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30010459

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
reproductive organSMED30010459SMESG000048415.1 SMESG000048414.1 Contig43048newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30010459SMESG000048415.1 SMESG000048414.1 Contig43048uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
gutSMED30010459SMESG000048415.1 SMESG000048414.1 GDAG01017383.1SmedSxl_ww_GDAG01.fsa_ntPMID:279364
whole organism adult hermaphrodite colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Cathepsin B vs. Ensembl Human
Match: CTSB (cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527])

HSP 1 Score: 356.681 bits (914), Expect = 5.480e-121
Identity = 175/329 (53.19%), Postives = 227/329 (69.00%), Query Frame = 2 
Query:   26 LLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            LLV A A +       P   PLS +L+NYVN   TTW+A        +S ++++ G        K PQ+     D+  P SFDAR +W +C +I+E+RDQ +CGSCWAFGA  A++DR CIH+NA     +S+EDL++CCG  CGDGCNGG+P  AW++W   G+V+GG Y SHVGC+ Y+ P C HHV G  P CTGE  TPKC + C+ GY  TY+ DK +G  SYS+SN E DIM EI  NGPVE  F VY+DF  Y++GVYQHV G ++GGHA++I+GWG+EN TPYWL+ANSWN  WGDNG+FKI+RG + CGIE E+VAG+P+
Sbjct:   11 LLVLANARS------RPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFL--GGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPR 331
[Close]
BLAST of Cathepsin B vs. Ensembl Human
Match: CTSB (cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527])

HSP 1 Score: 356.681 bits (914), Expect = 5.480e-121
Identity = 175/329 (53.19%), Postives = 227/329 (69.00%), Query Frame = 2 
Query:   26 LLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            LLV A A +       P   PLS +L+NYVN   TTW+A        +S ++++ G        K PQ+     D+  P SFDAR +W +C +I+E+RDQ +CGSCWAFGA  A++DR CIH+NA     +S+EDL++CCG  CGDGCNGG+P  AW++W   G+V+GG Y SHVGC+ Y+ P C HHV G  P CTGE  TPKC + C+ GY  TY+ DK +G  SYS+SN E DIM EI  NGPVE  F VY+DF  Y++GVYQHV G ++GGHA++I+GWG+EN TPYWL+ANSWN  WGDNG+FKI+RG + CGIE E+VAG+P+
Sbjct:   11 LLVLANARS------RPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFL--GGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPR 331
[Close]
BLAST of Cathepsin B vs. Ensembl Human
Match: CTSB (cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527])

HSP 1 Score: 356.681 bits (914), Expect = 5.480e-121
Identity = 175/329 (53.19%), Postives = 227/329 (69.00%), Query Frame = 2 
Query:   26 LLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            LLV A A +       P   PLS +L+NYVN   TTW+A        +S ++++ G        K PQ+     D+  P SFDAR +W +C +I+E+RDQ +CGSCWAFGA  A++DR CIH+NA     +S+EDL++CCG  CGDGCNGG+P  AW++W   G+V+GG Y SHVGC+ Y+ P C HHV G  P CTGE  TPKC + C+ GY  TY+ DK +G  SYS+SN E DIM EI  NGPVE  F VY+DF  Y++GVYQHV G ++GGHA++I+GWG+EN TPYWL+ANSWN  WGDNG+FKI+RG + CGIE E+VAG+P+
Sbjct:   11 LLVLANARS------RPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFL--GGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPR 331
[Close]
BLAST of Cathepsin B vs. Ensembl Human
Match: CTSB (cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527])

HSP 1 Score: 356.681 bits (914), Expect = 5.480e-121
Identity = 175/329 (53.19%), Postives = 227/329 (69.00%), Query Frame = 2 
Query:   26 LLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            LLV A A +       P   PLS +L+NYVN   TTW+A        +S ++++ G        K PQ+     D+  P SFDAR +W +C +I+E+RDQ +CGSCWAFGA  A++DR CIH+NA     +S+EDL++CCG  CGDGCNGG+P  AW++W   G+V+GG Y SHVGC+ Y+ P C HHV G  P CTGE  TPKC + C+ GY  TY+ DK +G  SYS+SN E DIM EI  NGPVE  F VY+DF  Y++GVYQHV G ++GGHA++I+GWG+EN TPYWL+ANSWN  WGDNG+FKI+RG + CGIE E+VAG+P+
Sbjct:   11 LLVLANARS------RPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFL--GGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPR 331
[Close]
BLAST of Cathepsin B vs. Ensembl Human
Match: CTSB (cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527])

HSP 1 Score: 356.681 bits (914), Expect = 5.480e-121
Identity = 175/329 (53.19%), Postives = 227/329 (69.00%), Query Frame = 2 
Query:   26 LLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            LLV A A +       P   PLS +L+NYVN   TTW+A        +S ++++ G        K PQ+     D+  P SFDAR +W +C +I+E+RDQ +CGSCWAFGA  A++DR CIH+NA     +S+EDL++CCG  CGDGCNGG+P  AW++W   G+V+GG Y SHVGC+ Y+ P C HHV G  P CTGE  TPKC + C+ GY  TY+ DK +G  SYS+SN E DIM EI  NGPVE  F VY+DF  Y++GVYQHV G ++GGHA++I+GWG+EN TPYWL+ANSWN  WGDNG+FKI+RG + CGIE E+VAG+P+
Sbjct:   11 LLVLANARS------RPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFL--GGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPR 331
[Close]
BLAST of Cathepsin B vs. Ensembl Celegans
Match: F57F5.1 (pep chromosome:WBcel235:V:12003028:12004600:1 gene:WBGene00010204.1 transcript:F57F5.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F57F5.1)

HSP 1 Score: 295.819 bits (756), Expect = 1.682e-97
Identity = 158/324 (48.77%), Postives = 219/324 (67.59%), Query Frame = 2 
Query:   71 IPIHSPL--SFDLINYVNYAQTTWKAAPTTRFQSVSDI--RKVLG--VMKDPNSFKLPQKKQ-LMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIY--PNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 1015
            IP+ + +    +L++YVN  QT++KA   + F S  D   ++++G  +++ P  +++ +     + D   PDSFD+R  W  C SI ++RDQS+CGSCWA  AA  ++DR CI SNA     IS++D+ +CCG  CG+GCNGG+P  AW ++V  G VTGG Y    GC+ Y +P C HHV G +  P  +  YPT KC+R+CQ+GY  TY+ D  FG+++Y++S K ++I  EIM +GPVE  F VY DF +Y  GVY H AG  LGGHAVK++GWG++N TPYWL ANSWN  WG+NGYF+IIRGVNECGIE  +V G+P+L
Sbjct:   28 IPVEAQMLRGQELVDYVNKVQTSFKAELGSYFSSYPDTIKKQLMGAKMVEIPEEYRVFEMTHPEVEDAAVPDSFDSRTAWPNCPSISKIRDQSSCGSCWAVSAAETISDRICIASNAKTILSISADDINACCGMVCGNGCNGGYPIEAWRHYVKKGYVTGGSYQDKTGCKPYPYPPCEHHVNGTHYKPCPSNMYPTDKCERSCQAGYALTYQQDLHFGQSAYAVSKKAAEIQKEIMTHGPVEVAFTVYEDFEHYSGGVYVHTAGASLGGHAVKMLGWGVDNGTPYWLCANSWNEDWGENGYFRIIRGVNECGIEGGVVGGIPKL 351
[Close]
BLAST of Cathepsin B vs. Ensembl Celegans
Match: cpr-6 (Cathepsin B-like cysteine proteinase 6 [Source:UniProtKB/Swiss-Prot;Acc:P43510])

HSP 1 Score: 295.434 bits (755), Expect = 4.740e-97
Identity = 162/347 (46.69%), Postives = 220/347 (63.40%), Query Frame = 2 
Query:    8 LFFTVLLLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSV--SDIRKVLGVMKDPNSFKLPQK-KQLMS-----DMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIY--PNCTGEYPTPKCKRNCQSGYP-KTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 1015
            LF + +++    A N + ++ +        DLI+YVN  Q  W A    RF SV   + +   G+M   N  +L  K KQ +S     D+  P+SFD+R  W +C+SI+ +RDQS+CGSCWAFGA  AM+DR CI S+   +  +S++DL+SCC + CG GCNGG P  AW YWV DGIVTG  Y ++ GC+ Y FP C HH K  +  P     YPTPKC++ C S Y  KTY  DK FG ++Y + +    I  E+M +GP+E  F+VY DF NY  GVY H  G + GGHAVK+IGWGI++  PYW +ANSWN  WG++G+F+I+RGV+ECGIE  +V G+P+L
Sbjct:    5 LFLSCIVVAAYCACNDNLESVLEAAELDGDDLIDYVNENQNLWTAKKQRRFSSVYGENDKAKWGLMG-VNHVRLSVKGKQHLSKTKDLDLDIPESFDSRDNWPKCDSIKVIRDQSSCGSCWAFGAVEAMSDRICIASHGELQVTLSADDLLSCC-KSCGFGCNGGDPLAAWRYWVKDGIVTGSNYTANNGCKPYPFPPCEHHSKKTHFDPCPHDLYPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMTHGPLEIAFEVYEDFLNYDGGVYVHTGGKLGGGHAVKLIGWGIDDGIPYWTVANSWNTDWGEDGFFRILRGVDECGIESGVVGGIPKL 349
[Close]
BLAST of Cathepsin B vs. Ensembl Celegans
Match: cpr-6 (Cathepsin B-like cysteine proteinase 6 [Source:UniProtKB/Swiss-Prot;Acc:P43510])

HSP 1 Score: 292.738 bits (748), Expect = 6.929e-96
Identity = 158/317 (49.84%), Postives = 208/317 (65.62%), Query Frame = 2 
Query:   98 DLINYVNYAQTTWKAAPTTRFQSV--SDIRKVLGVMKDPNSFKLPQK-KQLMS-----DMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIY--PNCTGEYPTPKCKRNCQSGYP-KTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 1015
            DLI+YVN  Q  W A    RF SV   + +   G+M   N  +L  K KQ +S     D+  P+SFD+R  W +C+SI+ +RDQS+CGSCWAFGA  AM+DR CI S+   +  +S++DL+SCC + CG GCNGG P  AW YWV DGIVTG  Y ++ GC+ Y FP C HH K  +  P     YPTPKC++ C S Y  KTY  DK FG ++Y + +    I  E+M +GP+E  F+VY DF NY  GVY H  G + GGHAVK+IGWGI++  PYW +ANSWN  WG++G+F+I+RGV+ECGIE  +V G+P+L
Sbjct:   45 DLIDYVNENQNLWTAKKQRRFSSVYGENDKAKWGLMG-VNHVRLSVKGKQHLSKTKDLDLDIPESFDSRDNWPKCDSIKVIRDQSSCGSCWAFGAVEAMSDRICIASHGELQVTLSADDLLSCC-KSCGFGCNGGDPLAAWRYWVKDGIVTGSNYTANNGCKPYPFPPCEHHSKKTHFDPCPHDLYPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMTHGPLEIAFEVYEDFLNYDGGVYVHTGGKLGGGHAVKLIGWGIDDGIPYWTVANSWNTDWGEDGFFRILRGVDECGIESGVVGGIPKL 359
[Close]
BLAST of Cathepsin B vs. Ensembl Celegans
Match: cpr-6 (Cathepsin B-like cysteine proteinase 6 [Source:UniProtKB/Swiss-Prot;Acc:P43510])

HSP 1 Score: 292.738 bits (748), Expect = 7.089e-96
Identity = 158/317 (49.84%), Postives = 208/317 (65.62%), Query Frame = 2 
Query:   98 DLINYVNYAQTTWKAAPTTRFQSV--SDIRKVLGVMKDPNSFKLPQK-KQLMS-----DMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIY--PNCTGEYPTPKCKRNCQSGYP-KTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 1015
            DLI+YVN  Q  W A    RF SV   + +   G+M   N  +L  K KQ +S     D+  P+SFD+R  W +C+SI+ +RDQS+CGSCWAFGA  AM+DR CI S+   +  +S++DL+SCC + CG GCNGG P  AW YWV DGIVTG  Y ++ GC+ Y FP C HH K  +  P     YPTPKC++ C S Y  KTY  DK FG ++Y + +    I  E+M +GP+E  F+VY DF NY  GVY H  G + GGHAVK+IGWGI++  PYW +ANSWN  WG++G+F+I+RGV+ECGIE  +V G+P+L
Sbjct:   44 DLIDYVNENQNLWTAKKQRRFSSVYGENDKAKWGLMG-VNHVRLSVKGKQHLSKTKDLDLDIPESFDSRDNWPKCDSIKVIRDQSSCGSCWAFGAVEAMSDRICIASHGELQVTLSADDLLSCC-KSCGFGCNGGDPLAAWRYWVKDGIVTGSNYTANNGCKPYPFPPCEHHSKKTHFDPCPHDLYPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMTHGPLEIAFEVYEDFLNYDGGVYVHTGGKLGGGHAVKLIGWGIDDGIPYWTVANSWNTDWGEDGFFRILRGVDECGIESGVVGGIPKL 358
[Close]
BLAST of Cathepsin B vs. Ensembl Celegans
Match: cpr-5 (Cathepsin B-like cysteine proteinase 5 [Source:UniProtKB/Swiss-Prot;Acc:P43509])

HSP 1 Score: 288.886 bits (738), Expect = 8.926e-95
Identity = 168/352 (47.73%), Postives = 214/352 (60.80%), Query Frame = 2 
Query:   14 FTVLLLVFAGAANC---HRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQ-----LMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGE--KCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGI-YPNCTGEY-PTPKCKRNCQS--GYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL*KNN 1027
             + +LLV A +A     HR+A  P  +  +  LI+YVN AQ  W A        V    K+   + D   + +P K +      +SD I PD FDAR +W  C SI  +RDQS+CGSCWAF AA A++DR CI SN      +SSEDL+SCC     CG+GC GG+P  AW +WV  G+VTGG Y +  GC+ Y+   C   V G+ +P C  +  PTPKC  +C S   Y   Y  DK FG T+Y++  K   I  EI+ NGP+E  F VY DF  Y TGVY H AG  LGGHAVKI+GWG++N TPYWL+ANSWN  WG+ GYF+IIRG+NECGIE   VAG+P L ++N
Sbjct:    4 LSAILLVAAASAVVIPGHREA--PALTGQA--LIDYVNSAQKLWTAG-----HQVIPKEKITKKLMDVK-YLVPHKDEDIVATEVSDAI-PDHFDARDQWPNCMSINNIRDQSDCGSCWAFAAAEAISDRTCIASNGAVNTLLSSEDLLSCCTGMFSCGNGCEGGYPIQAWKWWVKHGLVTGGSYETQFGCKPYSIAPCGETVNGVKWPACPEDTEPTPKCVDSCTSKNNYATPYLQDKHFGSTAYAVGKKVEQIQTEILTNGPIEVAFTVYEDFYQYTTGVYVHTAGASLGGHAVKILGWGVDNGTPYWLVANSWNVAWGEKGYFRIIRGLNECGIEHSAVAGIPDLARHN 344
[Close]
BLAST of Cathepsin B vs. Ensembl Fly
Match: CtsB1 (gene:FBgn0030521 transcript:FBtr0346091)

HSP 1 Score: 304.294 bits (778), Expect = 7.283e-101
Identity = 164/344 (47.67%), Postives = 205/344 (59.59%), Query Frame = 2 
Query:   14 FTVLLLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSD--IRKVLGVMKDPNSFKLPQKKQLMSDMI------FPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGI--ENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 1015
              +LLLV   A+     +  P  S LS + I  V     TW         SV++  IR+++GV  D + F LP K++++ D+        P+ FD+R +W  C +I E+RDQ +CGSCWAFGA  AM+DR CIHS        S++DLVSCC   CG GCNGGFP  AW YW   GIV+GG YGS+ GC+ Y    C HHV G  P C     TPKC   CQSGY   Y  DK FG  SYS+     +I  EIM NGPVE  F VY D   Y+ GVYQH  G  LGGHA++I+GWG+  E   PYWLI NSWN  WGD+G+F+I+RG + CGIE  I AG+P+L
Sbjct:    1 MNLLLLVATAASVAALTSGEP--SLLSDEFIEVVRSKAKTWTVGRNFD-ASVTEGHIRRLMGVHPDAHKFALPDKREVLGDLYVNSVDELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSCC-HTCGFGCNGGFPGAAWSYWTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAHGGRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTVYEDLILYKDGVYQHEHGKELGGHAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGFFRILRGQDHCGIESSISAGLPKL 340
[Close]
BLAST of Cathepsin B vs. Ensembl Fly
Match: CtsB1 (gene:FBgn0030521 transcript:FBtr0073838)

HSP 1 Score: 304.294 bits (778), Expect = 7.283e-101
Identity = 164/344 (47.67%), Postives = 205/344 (59.59%), Query Frame = 2 
Query:   14 FTVLLLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSD--IRKVLGVMKDPNSFKLPQKKQLMSDMI------FPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGI--ENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 1015
              +LLLV   A+     +  P  S LS + I  V     TW         SV++  IR+++GV  D + F LP K++++ D+        P+ FD+R +W  C +I E+RDQ +CGSCWAFGA  AM+DR CIHS        S++DLVSCC   CG GCNGGFP  AW YW   GIV+GG YGS+ GC+ Y    C HHV G  P C     TPKC   CQSGY   Y  DK FG  SYS+     +I  EIM NGPVE  F VY D   Y+ GVYQH  G  LGGHA++I+GWG+  E   PYWLI NSWN  WGD+G+F+I+RG + CGIE  I AG+P+L
Sbjct:    1 MNLLLLVATAASVAALTSGEP--SLLSDEFIEVVRSKAKTWTVGRNFD-ASVTEGHIRRLMGVHPDAHKFALPDKREVLGDLYVNSVDELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSCC-HTCGFGCNGGFPGAAWSYWTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAHGGRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTVYEDLILYKDGVYQHEHGKELGGHAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGFFRILRGQDHCGIESSISAGLPKL 340
[Close]
BLAST of Cathepsin B vs. Ensembl Fly
Match: Swim (gene:FBgn0034709 transcript:FBtr0071785)

HSP 1 Score: 130.183 bits (326), Expect = 3.178e-33
Identity = 86/256 (33.59%), Postives = 124/256 (48.44%), Query Frame = 2 
Query:  257 FPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRN-CQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXX---XXKIIGWGIENN-TPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMP 1009
             P SF+A  +WS    I EV DQ  CG+ W     +  +DR+ I S      ++S+++++SC   +   GC GG    AW Y    G+V            +  +P   H        C   + +   + N CQ   P     D  +        N+E+DIM EI  +GPV+A   V  DF  Y  GVY+  A          +VK++GWG E+N   YW+ ANSW   WG++GYF+I+RG NECGIE+ ++A  P
Sbjct:  187 LPSSFNALDKWSS--YISEVPDQGWCGASWVLSTTSVASDRFAIQSKGKENVQLSAQNILSCTRRQ--QGCEGGHLDAAWRYLHKKGVV-----------DENCYPYTQHR-----DTCKIRHNSRSLRANGCQK--PVNVDRDSLYTVGPAYSLNREADIMAEIFHSGPVQATMRVNRDFFAYSGGVYRETAANRKAPTGFHSVKLVGWGEEHNGEKYWIAANSWGSWWGEHGYFRILRGSNECGIEEYVLASWP 420
[Close]
BLAST of Cathepsin B vs. Ensembl Fly
Match: Swim (gene:FBgn0034709 transcript:FBtr0071784)

HSP 1 Score: 130.183 bits (326), Expect = 3.178e-33
Identity = 86/256 (33.59%), Postives = 124/256 (48.44%), Query Frame = 2 
Query:  257 FPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRN-CQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXX---XXKIIGWGIENN-TPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMP 1009
             P SF+A  +WS    I EV DQ  CG+ W     +  +DR+ I S      ++S+++++SC   +   GC GG    AW Y    G+V            +  +P   H        C   + +   + N CQ   P     D  +        N+E+DIM EI  +GPV+A   V  DF  Y  GVY+  A          +VK++GWG E+N   YW+ ANSW   WG++GYF+I+RG NECGIE+ ++A  P
Sbjct:  187 LPSSFNALDKWSS--YISEVPDQGWCGASWVLSTTSVASDRFAIQSKGKENVQLSAQNILSCTRRQ--QGCEGGHLDAAWRYLHKKGVV-----------DENCYPYTQHR-----DTCKIRHNSRSLRANGCQK--PVNVDRDSLYTVGPAYSLNREADIMAEIFHSGPVQATMRVNRDFFAYSGGVYRETAANRKAPTGFHSVKLVGWGEEHNGEKYWIAANSWGSWWGEHGYFRILRGSNECGIEEYVLASWP 420
[Close]
BLAST of Cathepsin B vs. Ensembl Fly
Match: CG4847 (gene:FBgn0034229 transcript:FBtr0086934)

HSP 1 Score: 86.2705 bits (212), Expect = 4.168e-18
Identity = 88/333 (26.43%), Postives = 139/333 (41.74%), Query Frame = 2 
Query:   11 FFTVLLLVFAGAANCHRKAHIPIHSPLSF-DLINYVNYAQTT-WKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCG-EKCG-DGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFN-GPVEAGFDVYADFPNYRTGVYQXXX-XXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDE 991
            F +   LV AG A   +  H    +  +F DL +    +Q T  K +P  + ++ + ++ V           LP K         PD+FD    W E   +  V+ Q  CGSCWAF    A+       + +   P +S ++LV C   E  G +GC+GGF                         Q+ AF       KG+  +  G YP    K  C+    K+    + F     +I  K+ + + +++   GPV    +      NY  G+Y           H++ ++G+G E    YW++ NSW+ TWG+ GYF++ RG N C I +E
Sbjct:  106 FASTKNLVEAGNAAFAQGVHTFKQAVNAFADLTHSEFLSQLTGLKRSPEAKARAAASLKLV----------NLPAKP-------IPDAFD----WREHGGVTPVKFQGTCGSCWAFATTGAIEGHTFRKTGSL--PNLSEQNLVDCGPVEDFGLNGCDGGF-------------------------QEAAFCFIDEVQKGV--SQEGAYPYIDNKGTCKYDGSKSGATLQGFA----AIPPKDEEQLKKVVATLGPVACSVNGLETLKNYAGGIYNDDECNKGEPNHSILVVGYGSEKGQDYWIVKNSWDDTWGEKGYFRLPRGKNYCFIAEE 384
[Close]
BLAST of Cathepsin B vs. Ensembl Zebrafish
Match: ctsba (cathepsin Ba [Source:ZFIN;Acc:ZDB-GENE-040426-2650])

HSP 1 Score: 333.569 bits (854), Expect = 2.287e-112
Identity = 166/315 (52.70%), Postives = 216/315 (68.57%), Query Frame = 2 
Query:   74 PIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGV-MKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEY-PTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            P   PLS +++N++N A TTW A    R    S ++K+ G  +K P   KLP   Q    +  P +FDAR +W  C +++E+RDQ +CGSCWAFGAA A++DR CIHS+A     ISS+DL++CC + CG GCNGG+P+ AW +W T+G+VTGG Y SH+GC+ Y    C HHV G  P C+GE   TP C   C+ GY  +Y+ DK FGKTSYS+ + ++ IM E+  NGPVE  F VY DF  Y++GVYQH++G  +GGHA+KI+GWG EN  PYWL ANSWN  WGDNGYFKI+RG + CGIE EIVAG+P 
Sbjct:   20 PRLPPLSHEMVNFINKANTTWTAGHNFRDVDYSYVKKLCGTFLKGP---KLPVMVQYTEGLKLPKNFDAREQWPNCPTLKEIRDQGSCGSCWAFGAAEAISDRVCIHSDAKVSVEISSQDLLTCC-DSCGMGCNGGYPSAAWDFWATEGLVTGGLYNSHIGCRPYTIEPCEHHVNGSRPPCSGEGGDTPNCDMKCEPGYSPSYKQDKHFGKTSYSVPSNQNSIMAELFKNGPVEGAFTVYEDFLLYKSGVYQHMSGSPVGGHAIKILGWGEENGVPYWLAANSWNTDWGDNGYFKILRGEDHCGIESEIVAGIPM 330
[Close]
BLAST of Cathepsin B vs. Ensembl Zebrafish
Match: ctsbb (cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1])

HSP 1 Score: 317.775 bits (813), Expect = 4.315e-106
Identity = 159/309 (51.46%), Postives = 212/309 (68.61%), Query Frame = 2 
Query:   98 DLINYVNYAQTTWKAAPTTRFQSVSD--IRKVLG-VMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 1015
            ++I+++N A++TW A     F +V    ++ + G V+K P   +LP   +  +++  PDSFD R +W  C+++ ++RDQ +CGSCWAFGA  +++DR CIHS     P IS+EDL+SCC ++CG GC+GGFP  AW YW   G+VTGG Y S VGC+ Y+   C HHV G  P C+GE  TPKC   C   Y   Y+ DK FG   Y++ + +  IM E+  NGPVEA F VY DFP Y++GVYQH+ G  LGGHAVKI+GWG EN TP+WL+ANSWN  WGDNGYFKI+RG +ECGIE E+VAG+P+L
Sbjct:   24 EMISFINAARSTWTAG--VNFDNVPKKYLKSLCGTVLKGP---RLPHTVKHSTNVKLPDSFDLRDQWPNCKTLNQIRDQGSCGSCWAFGAVESISDRICIHSKGKQSPEISAEDLLSCC-DQCGFGCSGGFPAEAWDYWRRSGLVTGGLYNSDVGCRPYSIAPCEHHVNGTRPPCSGEQDTPKCTGVCIPKYSVPYKQDKHFGSKVYNVPSDQQQIMTELYTNGPVEAAFTVYEDFPLYKSGVYQHLTGSALGGHAVKILGWGEENGTPFWLVANSWNSDWGDNGYFKILRGHDECGIESEMVAGLPKL 326
[Close]
BLAST of Cathepsin B vs. Ensembl Zebrafish
Match: ctsba (cathepsin Ba [Source:ZFIN;Acc:ZDB-GENE-040426-2650])

HSP 1 Score: 259.61 bits (662), Expect = 4.509e-84
Identity = 132/268 (49.25%), Postives = 179/268 (66.79%), Query Frame = 2 
Query:   74 PIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGV-MKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGE-YPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIG 871
            P   PLS +++N++N A TTW A    R    S ++K+ G  +K P   KLP   Q    +  P +FDAR +W  C +++E+RDQ +CGSCWAFGAA A++DR CIHS+A     ISS+DL++CC + CG GCNGG+P+ AW +W T+G+VTGG Y SH+GC+ Y    C HHV G  P C+GE   TP C   C+ GY  +Y+ DK FGKTSYS+ + ++ IM E+  NGPVE  F VY DF  Y++GVYQH++G  +GGHA+KI+G
Sbjct:   20 PRLPPLSHEMVNFINKANTTWTAGHNFRDVDYSYVKKLCGTFLKGP---KLPVMVQYTEGLKLPKNFDAREQWPNCPTLKEIRDQGSCGSCWAFGAAEAISDRVCIHSDAKVSVEISSQDLLTCC-DSCGMGCNGGYPSAAWDFWATEGLVTGGLYNSHIGCRPYTIEPCEHHVNGSRPPCSGEGGDTPNCDMKCEPGYSPSYKQDKHFGKTSYSVPSNQNSIMAELFKNGPVEGAFTVYEDFLLYKSGVYQHMSGSPVGGHAIKILG 283
[Close]
BLAST of Cathepsin B vs. Ensembl Zebrafish
Match: tinagl1 (tubulointerstitial nephritis antigen-like 1 [Source:ZFIN;Acc:ZDB-GENE-060503-240])

HSP 1 Score: 136.346 bits (342), Expect = 3.905e-35
Identity = 102/322 (31.68%), Postives = 151/322 (46.89%), Query Frame = 2 
Query:   98 DLINYVNYAQTTWKAAPTTRFQSVS---DIRKVLGVMKDPNSFKLPQKKQLMSDMI--FPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQD-YAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKT--YRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQX--------XXXXXXXXXXXKIIGWGIENN-----TPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVA 1000
            D+I  +N     W+AA  ++F  ++    +R  LG  +   +     + Q+  +     P  F+A  +W     I E  DQ NC + WAF  AA  +DR  I S     P++S ++L+SC   +  DGC GG   GAW +    G+VT          QD Y F         +           + KR   +  P +  Y ND       Y +S  E++IM EIM NGPV+A  +V+ DF  Y++G+++H                H+V+I GWG E +       YW+ ANSW   WG++GYF+I RGVNEC IE  ++ 
Sbjct:  142 DMIQEINRRDYGWRAANYSQFWGMTLDEGLRFRLGTKRPTRTIMNMNEMQMNMNGNDHLPSYFNAVDKWPG--KIHEPLDQGNCNASWAFSTAAVASDRISIQSMGHMTPQLSPQNLISC-DTRHQDGCAGGRIDGAWWFMRRRGVVT----------QDCYPFSPPEQSAVEVARCMMQSRAVGRGKRQATAHCPNSHSYHNDIYQSTPPYRLSTNENEIMKEIMDNGPVQAIMEVHEDFFVYKSGIFRHTDVNYHKPSQYRKHATHSVRITGWGEERDYSGRTRKYWIGANSWGKNWGEDGYFRIARGVNECDIETFVIG 450
[Close]
BLAST of Cathepsin B vs. Ensembl Zebrafish
Match: ctsc (cathepsin C [Source:ZFIN;Acc:ZDB-GENE-030619-9])

HSP 1 Score: 113.235 bits (282), Expect = 5.171e-27
Identity = 94/327 (28.75%), Postives = 141/327 (43.12%), Query Frame = 2 
Query:  101 LINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQ---LMSDMIFPDSFDARLEWSECESIR---EVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEY---GSHVGCQDYAFPKCS-------HHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXX------XXXXXXXKIIGWGIENNT--PYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMP 1009
             ++ +N  Q +W A     F     I ++L     P S ++P++ +   + +D           +W     +     VR+Q+ CGSC++F     +  R  I +N T +P  S + +VSC   +   GC+GGFP     Y    GIV    +   GS   C   A  KC+       H+V G Y  C+                                    ES +MLE++ NGP+    +VY DF NY+ G+Y H           L  HAV ++G+G  + T   YW++ NSW   WG+NG+F+I RG +EC IE   VA  P
Sbjct:  167 FVDEINSVQKSWTAT-VYSFHETLSIHEMLRRSGGPAS-RIPRRVRPVTVAADSKAAAGLPQHWDWRNVNGVNFVSPVRNQAQCGSCYSFATMGMLEARVRIQTNNTQQPVFSPQQVVSC--SQYSQGCDGGFPYLIGKYIQDFGIVEEDCFPYTGSDSPCNLPA--KCTKYYASDYHYVGGFYGGCS------------------------------------ESAMMLELVKNGPMGVALEVYPDFMNYKEGIYHHTGLRDANNPFELTNHAVLLVGYGQCHKTGEKYWIVKNSWGSGWGENGFFRIRRGTDECAIESIAVAATP 451
[Close]
BLAST of Cathepsin B vs. Ensembl Xenopus
Match: ctsb (cathepsin B [Source:NCBI gene;Acc:394833])

HSP 1 Score: 352.829 bits (904), Expect = 1.085e-119
Identity = 173/332 (52.11%), Postives = 224/332 (67.47%), Query Frame = 2 
Query:   20 VLLLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEY-PTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            V++L F  +    R  H+P  +PLS D++NY+N   TTWKA        +  ++++ G     N  +L ++      M  PDSFD+R  W  C +IREVRDQ +CGSCWAFGA  A++DR C+H+N      +S+EDL+SCCG +CG GCNGG+P+GAW +W   G+V+GG Y SH+GC+ Y+ P C HHV G  P C GE   TPKC + C+ GY   Y +DK FG TSY + + E +IM EI  NGPVE  F VYADFP Y++GVYQH  G  LGGHA+KI+GWG+EN TPYWL ANSWN  WGDNG+FKI+RG + CGIE EIVAG+P+
Sbjct:    5 VVVLCFLASIASAR--HLPFFAPLSGDMVNYINKMNTTWKAGHNFANADLHYVKRLCGTHL--NGPQLQKRFGFADGMELPDSFDSRAAWPNCPTIREVRDQGSCGSCWAFGAVEAISDRVCVHTNGKVNVEVSAEDLLSCCGFECGMGCNGGYPSGAWKFWTETGLVSGGLYDSHLGCRPYSIPPCEHHVNGSRPACKGEEGDTPKCVKQCEDGYAPVYGSDKHFGATSYGVPSSEKEIMAEIYKNGPVEGAFLVYADFPMYKSGVYQHETGEELGGHAIKILGWGVENGTPYWLCANSWNTDWGDNGFFKILRGKDHCGIESEIVAGIPK 332
[Close]
BLAST of Cathepsin B vs. Ensembl Xenopus
Match: ctsb (cathepsin B [Source:NCBI gene;Acc:394833])

HSP 1 Score: 338.576 bits (867), Expect = 2.616e-113
Identity = 166/323 (51.39%), Postives = 216/323 (66.87%), Query Frame = 2 
Query:   20 VLLLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEY-PTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIE 985
            V++L F  +    R  H+P  +PLS D++NY+N   TTWKA        +  ++++ G     N  +L ++      M  PDSFD+R  W  C +IREVRDQ +CGSCWAFGA  A++DR C+H+N      +S+EDL+SCCG +CG GCNGG+P+GAW +W   G+V+GG Y SH+GC+ Y+ P C HHV G  P C GE   TPKC + C+ GY   Y +DK FG TSY + + E +IM EI  NGPVE  F VYADFP Y++GVYQH  G  LGGHA+KI+GWG+EN TPYWL ANSWN  WGDNG+FKI+RG + CGI+
Sbjct:    5 VVVLCFLASIASAR--HLPFFAPLSGDMVNYINKMNTTWKAGHNFANADLHYVKRLCGTHL--NGPQLQKRFGFADGMELPDSFDSRAAWPNCPTIREVRDQGSCGSCWAFGAVEAISDRVCVHTNGKVNVEVSAEDLLSCCGFECGMGCNGGYPSGAWKFWTETGLVSGGLYDSHLGCRPYSIPPCEHHVNGSRPACKGEEGDTPKCVKQCEDGYAPVYGSDKHFGATSYGVPSSEKEIMAEIYKNGPVEGAFLVYADFPMYKSGVYQHETGEELGGHAIKILGWGVENGTPYWLCANSWNTDWGDNGFFKILRGKDHCGID 323
[Close]
BLAST of Cathepsin B vs. Ensembl Xenopus
Match: ctsb (cathepsin B [Source:NCBI gene;Acc:394833])

HSP 1 Score: 322.398 bits (825), Expect = 5.423e-108
Identity = 154/269 (57.25%), Postives = 192/269 (71.38%), Query Frame = 2 
Query:  209 NSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEY-PTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            N  +L ++      M  PDSFD+R  W  C +IREVRDQ +CGSCWAFGA  A++DR C+H+N      +S+EDL+SCCG +CG GCNGG+P+GAW +W   G+V+GG Y SH+GC+ Y+ P C HHV G  P C GE   TPKC + C+ GY   Y +DK FG TSY + + E +IM EI  NGPVE  F VYADFP Y++GVYQH  G  LGGHA+KI+GWG+EN TPYWL ANSWN  WGDNG+FKI+RG + CGIE EIVAG+P+
Sbjct:   50 NGPQLQKRFGFADGMELPDSFDSRAAWPNCPTIREVRDQGSCGSCWAFGAVEAISDRVCVHTNGKVNVEVSAEDLLSCCGFECGMGCNGGYPSGAWKFWTETGLVSGGLYDSHLGCRPYSIPPCEHHVNGSRPACKGEEGDTPKCVKQCEDGYAPVYGSDKHFGATSYGVPSSEKEIMAEIYKNGPVEGAFLVYADFPMYKSGVYQHETGEELGGHAIKILGWGVENGTPYWLCANSWNTDWGDNGFFKILRGKDHCGIESEIVAGIPK 318
[Close]
BLAST of Cathepsin B vs. Ensembl Xenopus
Match: ctsb (cathepsin B [Source:NCBI gene;Acc:394833])

HSP 1 Score: 321.242 bits (822), Expect = 6.474e-107
Identity = 160/317 (50.47%), Postives = 207/317 (65.30%), Query Frame = 2 
Query:   20 VLLLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEY-PTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGV 967
            V++L F  +    R  H+P  +PLS D++NY+N   TTWKA        +  ++++ G     N  +L ++      M  PDSFD+R  W  C +IREVRDQ +CGSCWAFGA  A++DR C+H+N      +S+EDL+SCCG +CG GCNGG+P+GAW +W   G+V+GG Y SH+GC+ Y+ P C HHV G  P C GE   TPKC + C+ GY   Y +DK FG TSY + + E +IM EI  NGPVE  F VYADFP Y++GVYQH  G  LGGHA+KI+GWG+EN TPYWL ANSWN  WGDNG   +  GV
Sbjct:   29 VVVLCFLASIASAR--HLPFFAPLSGDMVNYINKMNTTWKAGHNFANADLHYVKRLCGTHL--NGPQLQKRFGFADGMELPDSFDSRAAWPNCPTIREVRDQGSCGSCWAFGAVEAISDRVCVHTNGKVNVEVSAEDLLSCCGFECGMGCNGGYPSGAWKFWTETGLVSGGLYDSHLGCRPYSIPPCEHHVNGSRPACKGEEGDTPKCVKQCEDGYAPVYGSDKHFGATSYGVPSSEKEIMAEIYKNGPVEGAFLVYADFPMYKSGVYQHETGEELGGHAIKILGWGVENGTPYWLCANSWNTDWGDNGKRWLFSGV 341
[Close]
BLAST of Cathepsin B vs. Ensembl Xenopus
Match: TINAGL1 (tubulointerstitial nephritis antigen-like 1 [Source:NCBI gene;Acc:100124858])

HSP 1 Score: 133.265 bits (334), Expect = 4.989e-34
Identity = 100/319 (31.35%), Postives = 150/319 (47.02%), Query Frame = 2 
Query:  104 INYVNYAQTTWKAAPTTRFQSVS---DIRKVLGVMKDPNS-FKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTP-KCKRNCQSGYPKTYRNDKQFGKTS--YSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXX--------XXXXKIIGWGIENNT-----PYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVA 1000
            I  +N    +W A   ++F  ++    I+  LG  K  +S   + +    M++ I P  F+A  +W     + E  DQ NC   WAF  AA  +DR  I S       +S ++L+SC   +   GC GG   GAW Y    G+V+           +  +P  S +  G    C  +  +  + KR   +  P  Y +  +  +++  Y +++ E DIM E+  NGPV+A  +V+ DF  Y++G+Y+H                H+VKI GWG E         YWL ANSW   WG++GYF+I RG NEC IE  IV 
Sbjct:  136 IEAINTGDYSWTAGNYSQFWGMTLDEGIQYRLGTAKPSSSVMNMNEIHVNMNNDILPSHFNAAEKWPGL--VHEPLDQGNCAGSWAFSTAAVASDRISIQSMGHMTQSLSPQNLLSC-DTRNQHGCRGGRVDGAWWYLRRRGVVS-----------EPCYPFTSLNTNGHSAPCMMQSRSMGRGKRQATNNCPNQYYSSNEIYQSTPAYRLASSEKDIMKELYENGPVQAIMEVHEDFFMYKSGIYRHTPVTEREPEHHRRHGTHSVKITGWGEERGRDGQTHKYWLAANSWGRDWGEDGYFRIARGENECEIETFIVG 440
[Close]
BLAST of Cathepsin B vs. Ensembl Mouse
Match: Ctsb (cathepsin B [Source:MGI Symbol;Acc:MGI:88561])

HSP 1 Score: 352.829 bits (904), Expect = 9.534e-120
Identity = 170/314 (54.14%), Postives = 223/314 (71.02%), Query Frame = 2 
Query:   74 PIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLG-VMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            P   PLS DLINY+N   TTW+A        +S ++K+ G V+  P   KLP +     D+  P++FDAR +WS C +I ++RDQ +CGSCWAFGA  A++DR CIH+N      +S+EDL++CCG +CGDGCNGG+P+GAW +W   G+V+GG Y SHVGC  Y  P C HHV G  P CTGE  TP+C ++C++GY  +Y+ DK FG TSYS+SN   +IM EI  NGPVE  F V++DF  Y++GVY+H AG ++GGHA++I+GWG+EN  PYWL ANSWN  WGDNG+FKI+RG N CGIE EIVAG+P+
Sbjct:   21 PSFHPLSDDLINYINKQNTTWQAGRNFYNVDISYLKKLCGTVLGGP---KLPGRVAFGEDIDLPETFDAREQWSNCPTIGQIRDQGSCGSCWAFGAVEAISDRTCIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWSFWTKKGLVSGGVYNSHVGCLPYTIPPCEHHVNGSRPPCTGEGDTPRCNKSCEAGYSPSYKEDKHFGYTSYSVSNSVKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDMMGGHAIRILGWGVENGVPYWLAANSWNLDWGDNGFFKILRGENHCGIESEIVAGIPR 331
[Close]
BLAST of Cathepsin B vs. Ensembl Mouse
Match: Tinagl1 (tubulointerstitial nephritis antigen-like 1 [Source:MGI Symbol;Acc:MGI:2137617])

HSP 1 Score: 137.117 bits (344), Expect = 2.317e-35
Identity = 104/324 (32.10%), Postives = 151/324 (46.60%), Query Frame = 2 
Query:   98 DLINYVNYAQTTWKAAPTTRFQSVS---DIRKVLGVMKDPNSFKLPQKK---QLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYA--FPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYP--KTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVY--------QXXXXXXXXXXXXKIIGWGIE-----NNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVA 1000
            D+I  +N     W+A   + F  ++    IR  LG ++ P+S  +   +    L    + P +F+A  +W     I E  DQ NC   WAF  AA  +DR  IHS     P +S ++L+SC       GC GG   GAW +    G+V+   Y      Q+ A   P+C  H + +           + KR   S  P  +   ND      +Y + + E +IM E+M NGPV+A  +V+ DF  Y+ G+Y        +       G H+VKI GWG E         YW  ANSW P WG+ G+F+I+RG NEC IE  ++ 
Sbjct:  144 DMIKAINRGNYGWQAGNHSAFWGMTLDEGIRYRLGTIR-PSSTVMNMNEIYTVLGQGEVLPTAFEASEKWPNL--IHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPILSPQNLLSCDTHH-QQGCRGGRLDGAWWFLRRRGVVSDNCYPFSGREQNEASPTPRCMMHSRAM----------GRGKRQATSRCPNGQVDSNDIYQVTPAYRLGSDEKEIMKELMENGPVQALMEVHEDFFLYQRGIYSHTPVSQGRPEQYRRHGTHSVKITGWGEETLPDGRTIKYWTAANSWGPWWGERGHFRIVRGTNECDIETFVLG 453
[Close]
BLAST of Cathepsin B vs. Ensembl Mouse
Match: Tinagl1 (tubulointerstitial nephritis antigen-like 1 [Source:MGI Symbol;Acc:MGI:2137617])

HSP 1 Score: 137.117 bits (344), Expect = 2.317e-35
Identity = 104/324 (32.10%), Postives = 151/324 (46.60%), Query Frame = 2 
Query:   98 DLINYVNYAQTTWKAAPTTRFQSVS---DIRKVLGVMKDPNSFKLPQKK---QLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYA--FPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYP--KTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVY--------QXXXXXXXXXXXXKIIGWGIE-----NNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVA 1000
            D+I  +N     W+A   + F  ++    IR  LG ++ P+S  +   +    L    + P +F+A  +W     I E  DQ NC   WAF  AA  +DR  IHS     P +S ++L+SC       GC GG   GAW +    G+V+   Y      Q+ A   P+C  H + +           + KR   S  P  +   ND      +Y + + E +IM E+M NGPV+A  +V+ DF  Y+ G+Y        +       G H+VKI GWG E         YW  ANSW P WG+ G+F+I+RG NEC IE  ++ 
Sbjct:  144 DMIKAINRGNYGWQAGNHSAFWGMTLDEGIRYRLGTIR-PSSTVMNMNEIYTVLGQGEVLPTAFEASEKWPNL--IHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPILSPQNLLSCDTHH-QQGCRGGRLDGAWWFLRRRGVVSDNCYPFSGREQNEASPTPRCMMHSRAM----------GRGKRQATSRCPNGQVDSNDIYQVTPAYRLGSDEKEIMKELMENGPVQALMEVHEDFFLYQRGIYSHTPVSQGRPEQYRRHGTHSVKITGWGEETLPDGRTIKYWTAANSWGPWWGERGHFRIVRGTNECDIETFVLG 453
[Close]
BLAST of Cathepsin B vs. Ensembl Mouse
Match: Tinagl1 (tubulointerstitial nephritis antigen-like 1 [Source:MGI Symbol;Acc:MGI:2137617])

HSP 1 Score: 137.117 bits (344), Expect = 2.317e-35
Identity = 104/324 (32.10%), Postives = 151/324 (46.60%), Query Frame = 2 
Query:   98 DLINYVNYAQTTWKAAPTTRFQSVS---DIRKVLGVMKDPNSFKLPQKK---QLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYA--FPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYP--KTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVY--------QXXXXXXXXXXXXKIIGWGIE-----NNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVA 1000
            D+I  +N     W+A   + F  ++    IR  LG ++ P+S  +   +    L    + P +F+A  +W     I E  DQ NC   WAF  AA  +DR  IHS     P +S ++L+SC       GC GG   GAW +    G+V+   Y      Q+ A   P+C  H + +           + KR   S  P  +   ND      +Y + + E +IM E+M NGPV+A  +V+ DF  Y+ G+Y        +       G H+VKI GWG E         YW  ANSW P WG+ G+F+I+RG NEC IE  ++ 
Sbjct:  144 DMIKAINRGNYGWQAGNHSAFWGMTLDEGIRYRLGTIR-PSSTVMNMNEIYTVLGQGEVLPTAFEASEKWPNL--IHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPILSPQNLLSCDTHH-QQGCRGGRLDGAWWFLRRRGVVSDNCYPFSGREQNEASPTPRCMMHSRAM----------GRGKRQATSRCPNGQVDSNDIYQVTPAYRLGSDEKEIMKELMENGPVQALMEVHEDFFLYQRGIYSHTPVSQGRPEQYRRHGTHSVKITGWGEETLPDGRTIKYWTAANSWGPWWGERGHFRIVRGTNECDIETFVLG 453
[Close]
BLAST of Cathepsin B vs. Ensembl Mouse
Match: Tinagl1 (tubulointerstitial nephritis antigen-like 1 [Source:MGI Symbol;Acc:MGI:2137617])

HSP 1 Score: 130.954 bits (328), Expect = 2.496e-33
Identity = 101/312 (32.37%), Postives = 146/312 (46.79%), Query Frame = 2 
Query:  134 WKAAPTTRFQSVS---DIRKVLGVMKDPNSFKLPQKK---QLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYA--FPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYP--KTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVY--------QXXXXXXXXXXXXKIIGWGIE-----NNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVA 1000
            W+A   + F  ++    IR  LG ++ P+S  +   +    L    + P +F+A  +W     I E  DQ NC   WAF  AA  +DR  IHS     P +S ++L+SC       GC GG   GAW +    G+V+   Y      Q+ A   P+C  H + +           + KR   S  P  +   ND      +Y + + E +IM E+M NGPV+A  +V+ DF  Y+ G+Y        +       G H+VKI GWG E         YW  ANSW P WG+ G+F+I+RG NEC IE  ++ 
Sbjct:  125 WQAGNHSAFWGMTLDEGIRYRLGTIR-PSSTVMNMNEIYTVLGQGEVLPTAFEASEKWPNL--IHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPILSPQNLLSCDTHH-QQGCRGGRLDGAWWFLRRRGVVSDNCYPFSGREQNEASPTPRCMMHSRAM----------GRGKRQATSRCPNGQVDSNDIYQVTPAYRLGSDEKEIMKELMENGPVQALMEVHEDFFLYQRGIYSHTPVSQGRPEQYRRHGTHSVKITGWGEETLPDGRTIKYWTAANSWGPWWGERGHFRIVRGTNECDIETFVLG 422
[Close]
BLAST of Cathepsin B vs. UniProt/SwissProt
Match: sp|P83205|CATB_SHEEP (Cathepsin B OS=Ovis aries OX=9940 GN=CTSB PE=1 SV=2)

HSP 1 Score: 366.696 bits (940), Expect = 2.320e-124
Identity = 178/329 (54.10%), Postives = 235/329 (71.43%), Query Frame = 2 
Query:   26 LLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLG-VMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMP 1009
            LLV   A +     H P   PLS +++NYVN   TTWKA        +S ++K+ G ++  P   KLPQ+    +DM+ PDSFDAR +W  C +I+E+RDQ +CGSCWAFGA  A++DR CIHS       +S+ED+++CCG +CGDGCNGGFP+GAW++W   G+V+GG Y SHVGC+ Y+ P C HHV G  P CTGE  TPKC + C+ GY  +Y++DK FG +SYS+S+ E +IM EI  NGPVE  F VY+DF  Y++GVYQHV+G ++GGHA++I+GWG+EN+TPYWL+ NSWN  WGD G+FKI+RG + CGIE EIVAGMP
Sbjct:   11 LLVLTSARS---SLHFP---PLSDEMVNYVNKQNTTWKAGHNFYNVDLSYVKKLCGAILGGP---KLPQRDAFAADMVLPDSFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSKGRVNVEVSAEDMLTCCGSECGDGCNGGFPSGAWNFWTKKGLVSGGLYDSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPSYKDDKHFGCSSYSVSSNEKEIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEMMGGHAIRILGWGVENDTPYWLVGNSWNTDWGDKGFFKILRGQDHCGIESEIVAGMP 330
[Close]
BLAST of Cathepsin B vs. UniProt/SwissProt
Match: sp|Q4R5M2|CATB_MACFA (Cathepsin B OS=Macaca fascicularis OX=9541 GN=CTSB PE=2 SV=1)

HSP 1 Score: 359.377 bits (921), Expect = 1.848e-121
Identity = 172/313 (54.95%), Postives = 223/313 (71.25%), Query Frame = 2 
Query:   74 PIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            P   PLS +L+NYVN   TTW+A        VS ++++ G        K PQ+     D+  P+SFDAR +W +C +I+E+RDQ +CGSCWAFGA  A++DR CIH+NA     +S+EDL++CCG  CGDGCNGG+P GAW++W   G+V+GG Y SHVGC+ Y+ P C HHV G  P CTGE  TPKC + C+ GY  TY+ DK +G  SYS+SN E DIM EI  NGPVE  F VY+DF  Y++GVYQHV G ++GGHA++I+GWG+EN TPYWL+ANSWN  WGDNG+FKI+RG + CGIE E+VAG+P+
Sbjct:   21 PSFHPLSDELVNYVNKQNTTWQAGHNFYNVDVSYLKRLCGTFL--GGPKPPQRVMFTEDLKLPESFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGIMCGDGCNGGYPAGAWNFWTRKGLVSGGLYDSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPR 331
[Close]
BLAST of Cathepsin B vs. UniProt/SwissProt
Match: sp|P00787|CATB_RAT (Cathepsin B OS=Rattus norvegicus OX=10116 GN=Ctsb PE=1 SV=2)

HSP 1 Score: 359.377 bits (921), Expect = 1.951e-121
Identity = 172/314 (54.78%), Postives = 226/314 (71.97%), Query Frame = 2 
Query:   74 PIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLG-VMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            P   PLS D+INY+N   TTW+A        +S ++K+ G V+  PN   LP++     D+  P+SFDAR +WS C +I ++RDQ +CGSCWAFGA  AM+DR CIH+N      +S+EDL++CCG +CGDGCNGG+P+GAW++W   G+V+GG Y SH+GC  Y  P C HHV G  P CTGE  TPKC + C++GY  +Y+ DK +G TSYS+S+ E +IM EI  NGPVE  F V++DF  Y++GVY+H AG V+GGHA++I+GWGIEN  PYWL+ANSWN  WGDNG+FKI+RG N CGIE EIVAG+P+
Sbjct:   21 PSSHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCGTVLGGPN---LPERVGFSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENHCGIESEIVAGIPR 331
[Close]
BLAST of Cathepsin B vs. UniProt/SwissProt
Match: sp|A1E295|CATB_PIG (Cathepsin B OS=Sus scrofa OX=9823 GN=CTSB PE=1 SV=1)

HSP 1 Score: 358.992 bits (920), Expect = 2.842e-121
Identity = 176/334 (52.69%), Postives = 229/334 (68.56%), Query Frame = 2 
Query:    8 LFFTVLLLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMP 1009
            L  T+  LV   +A      H     PLS +L+N++N   TTW A        +S ++K+ G        KLPQ+    +DMI P SFDAR +W  C +I+E+RDQ +CGSCWAFGA  A++DR CI SN      +S+ED+++CCG++CGDGCNGGFP+GAW++W   G+V+GG Y SHVGC+ Y+ P C HHV G  P CTGE  TPKC + C+ GY  +Y+ DK FG +SYSIS  E +IM EI  NGPVE  F VY+DF  Y++GVYQHV G ++GGHA++I+GWG+EN TPYWL+ NSWN  WGDNG+FKI+RG + CGIE EIVAG+P
Sbjct:    4 LLATLSCLVLLTSA--RESLHF---QPLSDELVNFINKQNTTWTAGHNFYNVDLSYVKKLCGTFL--GGPKLPQRAAFAADMILPKSFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIRSNGRVNVEVSAEDMLTCCGDECGDGCNGGFPSGAWNFWTKKGLVSGGLYDSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYTPSYKEDKHFGCSSYSISRNEKEIMAEIYKNGPVEGAFTVYSDFLQYKSGVYQHVTGDLMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQDHCGIESEIVAGIP 330
[Close]
BLAST of Cathepsin B vs. UniProt/SwissProt
Match: sp|Q5R6D1|CATB_PONAB (Cathepsin B OS=Pongo abelii OX=9601 GN=CTSB PE=2 SV=1)

HSP 1 Score: 358.607 bits (919), Expect = 4.047e-121
Identity = 172/313 (54.95%), Postives = 222/313 (70.93%), Query Frame = 2 
Query:   74 PIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            P   PLS +L+NYVN   TTW+A        VS ++K+ G        K PQ+     D+  P+SFDAR +W +C +I+E+RDQ +CGSCWAFGA  A++DR CIH+NA     +S+EDL++CCG  CGDGCNGG+P  AW++W   G+V+GG Y SHVGC+ Y+ P C HHV G  P CTGE  TPKC + C+ GY  TY+ DK +G  SYS+SN E DIM EI  NGPVE  F VY+DF  Y++GVYQHV G ++GGHA++I+GWG+EN TPYWL+ANSWN  WGDNG+FKI+RG + CGIE E+VAG+P+
Sbjct:   21 PSFHPLSDELVNYVNKRNTTWQAGHNFYNVDVSYLKKLCGTFL--GGPKPPQRVMFTEDLKLPESFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSERDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPR 331
[Close]
BLAST of Cathepsin B vs. TrEMBL
Match: A0A267EBJ7 (Pept_C1 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig030029g2 PE=3 SV=1)

HSP 1 Score: 400.208 bits (1027), Expect = 5.364e-135
Identity = 198/336 (58.93%), Postives = 246/336 (73.21%), Query Frame = 2 
Query:   14 FTVLLLVFAGAANCHRK--AHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDM-IFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            F VLLL  A +A    +  A  P+H PL+ +LI+YVN   TTW+A  T+RF SVSD+R+VLGV+ +PN   +P      SD+   P  FDAR +W +C +I+EVRDQSNCGSCWAFGA  AM+DR+CIHS    +  +S+EDL++CCG  CG GCNGGF   AW YW   GIVTGG+YG+  GCQ Y+ P C HH  G Y  C+G+  TPKCKR+C SGY  TY NDK FG + Y++S+K+ DI  EIM NGPVEA F VYADFP+Y++GVYQH  GG LGGHAVKI+GWG+EN+TPYWL+ANSWNP WG +G+FKI+RG NECGIE  IVAG+P+
Sbjct:    5 FAVLLLAAASSAYPREESTAVKPMHEPLTQELIDYVNKVGTTWQAGRTSRFDSVSDVRRVLGVIANPNKPDIPVLSYPGSDIGDLPTEFDARTQWPKCPTIQEVRDQSNCGSCWAFGAVEAMSDRHCIHSGGKVQVHLSAEDLLACCGFSCGMGCNGGFLESAWQYWKKSGIVTGGQYGTKQGCQPYSLPHCDHHTTGKYQPCSGDSKTPKCKRDCISGYNMTYNNDKHFGASVYTVSSKQDDIAKEIMTNGPVEAAFTVYADFPSYKSGVYQHTTGGELGGHAVKILGWGVENSTPYWLVANSWNPDWGLDGFFKILRGKNECGIEGSIVAGIPK 340
[Close]
BLAST of Cathepsin B vs. TrEMBL
Match: A0A1I8HY66 (Pept_C1 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig030029g1 PE=3 SV=1)

HSP 1 Score: 399.823 bits (1026), Expect = 8.119e-135
Identity = 198/336 (58.93%), Postives = 245/336 (72.92%), Query Frame = 2 
Query:   14 FTVLLLVFAGAANCHRK--AHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDM-IFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            F VLLL  A +A    +  A  P+H PL+ +LI+YVN   TTW+A  T+RF SVSD+R+VLGV+ +PN   +P      SD+   P  FDAR +W +C +I+EVRDQSNCGSCWAFGA  AM+DR+CIHS    +  +S+EDL++CCG  CG GCNGGF   AW YW   GIVTGG+YG+  GCQ Y+ P C HH  G Y  C+G+  TPKCKR+C SGY  TY NDK FG + Y++S+K+ DI  EIM NGPVEA F VYADFP+Y++GVYQH  GG LGGHAVKI+GWG+EN TPYWL+ANSWNP WG +G+FKI+RG NECGIE  IVAG+P+
Sbjct:    5 FAVLLLAAASSAYPREESTAVKPMHEPLTQELIDYVNKVGTTWQAGRTSRFDSVSDVRRVLGVIANPNKPDIPVLSYPGSDIGDLPTEFDARTQWPKCPTIQEVRDQSNCGSCWAFGAVEAMSDRHCIHSGGKVQVHLSAEDLLACCGFSCGMGCNGGFLESAWQYWKKSGIVTGGQYGTKQGCQPYSLPHCDHHTTGKYQPCSGDSKTPKCKRDCISGYNMTYNNDKHFGASVYTVSSKQDDIAKEIMTNGPVEAAFTVYADFPSYKSGVYQHTTGGELGGHAVKILGWGVENGTPYWLVANSWNPDWGLDGFFKILRGKNECGIEGSIVAGIPK 340
[Close]
BLAST of Cathepsin B vs. TrEMBL
Match: A0A1I8I7B0 (Pept_C1 domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 392.889 bits (1008), Expect = 5.185e-132
Identity = 197/338 (58.28%), Postives = 244/338 (72.19%), Query Frame = 2 
Query:   14 FTVLLLVFAGAANCHRK--AHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDM-IFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIEN--NTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            F VLLL  A +A    +  A  P+H PL+ +LI+YVN   TTW+A  T+RF SVSD+R+VLGV+ +PN   +P      SD+   P  FDAR +W +C +I+EVRDQSNCGSCWAFGA  AM+DR+CIHS    +  +S+EDL++CCG  CG GCNGGF   AW YW   GIVTGG+YG+  GCQ Y+ P C HH  G Y  C+G+  TPKCKR+C SGY  TY NDK FG + Y++S+K+ DI  EIM NGPVEA F VYADFP+Y++GVYQH  GG LGGHAVKI+GWG+EN    PYWL+ANSWNP WG +G+FKI+RG NECGIE  IVAG+P+
Sbjct:    5 FAVLLLAAASSAYPREESTAVKPMHEPLTQELIDYVNKVGTTWQAGRTSRFDSVSDVRRVLGVIANPNKPDIPVLSYPGSDIGDLPTEFDARTQWPKCPTIQEVRDQSNCGSCWAFGAVEAMSDRHCIHSGGKVQVHLSAEDLLACCGFSCGMGCNGGFLESAWQYWKKSGIVTGGQYGTKQGCQPYSLPHCDHHTTGKYQPCSGDSKTPKCKRDCISGYNMTYNNDKHFGASVYTVSSKQDDIAKEIMTNGPVEAAFTVYADFPSYKSGVYQHTTGGELGGHAVKILGWGVENGRGAPYWLVANSWNPDWGLDGFFKILRGKNECGIEGSIVAGIPK 342
[Close]
BLAST of Cathepsin B vs. TrEMBL
Match: A0A369SCR6 (Cathepsin B OS=Trichoplax sp. H2 OX=287889 GN=TrispH2_002904 PE=3 SV=1)

HSP 1 Score: 390.963 bits (1003), Expect = 1.864e-131
Identity = 201/338 (59.47%), Postives = 237/338 (70.12%), Query Frame = 2 
Query:    2 SDLFFTVLLLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLP-QKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            + L    L  VF+      + A+ P H PLS DLI+YVN   T+WKA        VS ++ + G ++DPN F+LP    +  SD+  P SFD+R +W  C SIRE+RDQ +CGSCW+FGA  ++TDR CIHSN   K  IS+EDL++CC   CG GCNGGF   AWHYWV +GIVTGG+Y SH GCQ Y  PKC HHVKG +  C  E PTPKC + CQ GY KT+  DK FGK SYSI+N    I  EIM NGPVEA F VYADFP+Y++GVYQH  GG LGGHAVKI+GWG ENNTPYWLIANSWNPTWGD GYFKIIRG +ECGIE  IVAGMP+
Sbjct:    3 ASLIVITLFAVFSA-----QGAYFPNHQPLSQDLIDYVNLVSTSWKAGTNFAGLPVSYVKYLCGALEDPNHFQLPIHVHEDTSDL--PKSFDSRDKWRMCPSIREIRDQGSCGSCWSFGAVESITDRICIHSNGKVKVHISAEDLMTCC-TSCGMGCNGGFLPQAWHYWVNNGIVTGGQYHSHKGCQPYEIPKCEHHVKGPFKACGKELPTPKCSQKCQPGYNKTFNQDKHFGKKSYSITNNIQQIQKEIMMNGPVEAAFTVYADFPSYKSGVYQHTTGGPLGGHAVKILGWGTENNTPYWLIANSWNPTWGDKGYFKIIRGKDECGIESSIVAGMPK 332
[Close]
BLAST of Cathepsin B vs. TrEMBL
Match: B3S1Y3 (Pept_C1 domain-containing protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_63119 PE=3 SV=1)

HSP 1 Score: 390.963 bits (1003), Expect = 1.864e-131
Identity = 201/338 (59.47%), Postives = 237/338 (70.12%), Query Frame = 2 
Query:    2 SDLFFTVLLLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLP-QKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            + L    L  VF+      + A+ P H PLS DLI+YVN   T+WKA        VS ++ + G ++DPN F+LP    +  SD+  P SFD+R +W  C SIRE+RDQ +CGSCW+FGA  ++TDR CIHSN   K  IS+EDL++CC   CG GCNGGF   AWHYWV +GIVTGG+Y SH GCQ Y  PKC HHVKG +  C  E PTPKC + CQ GY KT+  DK FGK SYSI+N    I  EIM NGPVEA F VYADFP+Y++GVYQH  GG LGGHAVKI+GWG ENNTPYWLIANSWNPTWGD GYFKIIRG +ECGIE  IVAGMP+
Sbjct:    3 ASLIVITLFAVFSA-----QGAYFPNHQPLSQDLIDYVNLVSTSWKAGTNFAGLPVSYVKYLCGALEDPNHFQLPIHVHEDTSDL--PKSFDSRDKWRMCPSIREIRDQGSCGSCWSFGAVESITDRICIHSNGKVKVHISAEDLMTCC-TSCGMGCNGGFLPQAWHYWVNNGIVTGGQYHSHKGCQPYEIPKCEHHVKGPFKACGKELPTPKCSQKCQPGYNKTFNQDKHFGKKSYSITNNIQQIQKEIMMNGPVEAAFTVYADFPSYKSGVYQHTTGGPLGGHAVKILGWGTENNTPYWLIANSWNPTWGDKGYFKIIRGKDECGIESSIVAGMPK 332
[Close]
BLAST of Cathepsin B vs. Ensembl Cavefish
Match: ctsbb (cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1])

HSP 1 Score: 325.479 bits (833), Expect = 3.211e-109
Identity = 165/312 (52.88%), Postives = 210/312 (67.31%), Query Frame = 2 
Query:   83 SPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLG-VMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 1015
            SPLS D++N +N A TTW A         S ++ + G ++K P   +LP+  Q+   +  PD+FD+R +W +C +I ++RDQ +CGSCWAFGA  AM+DR CIHS       IS+EDL+SCC E CG GC GGFP  AW +W  +G+VTGG Y S +GC+ Y+   C HHV G  P C+GE  TP C + C  GY  +Y  D+ +GK SYSI +    IM EI  NGPVEA F VY DF  Y+TGVYQH  G VLGGHA+KI+GWG EN+TPYWL ANSWN  WGD GYFKI+RG + CGIE E+VAG+P++
Sbjct:   23 SPLSQDMVNTINKANTTWTAKLNFDNVDYSFLKSLCGTILKGP---RLPEMVQVEGKVDLPDNFDSRDQWPDCHTISQIRDQGSCGSCWAFGAVEAMSDRICIHSGGKVSVEISAEDLLSCCDE-CGMGCFGGFPDAAWDFWTKNGLVTGGLYDSSIGCRPYSLAPCEHHVNGTRPPCSGEEKTPDCVKQCIDGYTPSYAEDRHYGKRSYSIPSDPKQIMAEIYKNGPVEAAFTVYEDFLLYKTGVYQHRTGAVLGGHAIKILGWGEENSTPYWLAANSWNNDWGDKGYFKILRGQDHCGIESEMVAGIPKV 330
[Close]
BLAST of Cathepsin B vs. Ensembl Cavefish
Match: ctsba (cathepsin Ba [Source:ZFIN;Acc:ZDB-GENE-040426-2650])

HSP 1 Score: 313.923 bits (803), Expect = 4.874e-104
Identity = 165/319 (51.72%), Postives = 211/319 (66.14%), Query Frame = 2 
Query:   14 FTVLLLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVM-KDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEY-PTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRG 964
              VL L+ A + +  R    P    LS  LIN+VN A TTW+A         S + ++ G M K P   KLP   Q   DM  P+SFD R +W  C +++E+RDQ +CGSCWAFGAA A++DR CIHSN      ISSEDL++CC + CG GCNGG+P+ AW +W ++G+V+GG Y SH+GC+ Y+   C HHV G  P CTGE   TP C++ C+ GY  +Y+ DK FGK SYS+ + E  IM E+  NGPVE  F VY DF  Y++GVYQHV+G  +GGHA+KI+GWG EN TPYWL ANSWN  WG+NGYFKI+RG
Sbjct:    4 LAVLCLLSALSVSWTR----PHFGLLSDQLINHVNKANTTWRAGHNFPNADYSYVMQLCGTMLKGP---KLPVMVQYAGDMKLPESFDPREQWPNCPTLKEIRDQGSCGSCWAFGAAEAISDRICIHSNGKVSVEISSEDLLTCC-DSCGMGCNGGYPSAAWEFWESEGLVSGGLYNSHLGCRPYSIEPCEHHVNGSRPPCTGEGGDTPNCEKKCEPGYSVSYKQDKHFGKQSYSVPSDEKQIMQELYKNGPVEGAFTVYEDFLLYKSGVYQHVSGSAVGGHAIKILGWGKENGTPYWLAANSWNTDWGENGYFKILRG 314
[Close]
BLAST of Cathepsin B vs. Ensembl Cavefish
Match: ctsbb (cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1])

HSP 1 Score: 307.76 bits (787), Expect = 1.286e-102
Identity = 158/311 (50.80%), Postives = 197/311 (63.34%), Query Frame = 2 
Query:   83 SPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 1015
            SPLS D++N +N A TTW      + +   D+                           PD+FD+R +W +C +I ++RDQ +CGSCWAFGA  AM+DR CIHS       IS+EDL+SCC E CG GC GGFP  AW +W  +G+VTGG Y S +GC+ Y+   C HHV G  P C+GE  TP C + C  GY  +Y  D+ +GK SYSI +    IM EI  NGPVEA F VY DF  Y+TGVYQH  G VLGGHA+KI+GWG EN+TPYWL ANSWN  WGD GYFKI+RG + CGIE E+VAG+P++
Sbjct:   23 SPLSQDMVNTINKANTTWTVKCLVQVEGKVDL---------------------------PDNFDSRDQWPDCHTISQIRDQGSCGSCWAFGAVEAMSDRICIHSGGKVSVEISAEDLLSCCDE-CGMGCFGGFPDAAWDFWTKNGLVTGGLYDSSIGCRPYSLAPCEHHVNGTRPPCSGEEKTPDCVKQCIDGYTPSYAEDRHYGKRSYSIPSDPKQIMAEIYKNGPVEAAFTVYEDFLLYKTGVYQHRTGAVLGGHAIKILGWGEENSTPYWLAANSWNNDWGDKGYFKILRGQDHCGIESEMVAGIPKV 305
[Close]
BLAST of Cathepsin B vs. Ensembl Cavefish
Match: ctsbb (cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1])

HSP 1 Score: 290.426 bits (742), Expect = 8.385e-96
Identity = 150/288 (52.08%), Postives = 189/288 (65.62%), Query Frame = 2 
Query:   83 SPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLG-VMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNG 943
            SPLS D++N +N A TTW A         S ++ + G ++K P   +LP+  Q+   +  PD+FD+R +W +C +I ++RDQ +CGSCWAFGA  AM+DR CIHS       IS+EDL+SCC E CG GC GGFP  AW +W  +G+VTGG Y S +GC+ Y+   C HHV G  P C+GE  TP C + C  GY  +Y  D+ +GK SYSI +    IM EI  NGPVEA F VY DF  Y+TGVYQH  G VLGGHA+KI+GWG EN+TPYWL ANSWN  WGD G
Sbjct:   23 SPLSQDMVNTINKANTTWTAKLNFDNVDYSFLKSLCGTILKGP---RLPEMVQVEGKVDLPDNFDSRDQWPDCHTISQIRDQGSCGSCWAFGAVEAMSDRICIHSGGKVSVEISAEDLLSCCDE-CGMGCFGGFPDAAWDFWTKNGLVTGGLYDSSIGCRPYSLAPCEHHVNGTRPPCSGEEKTPDCVKQCIDGYTPSYAEDRHYGKRSYSIPSDPKQIMAEIYKNGPVEAAFTVYEDFLLYKTGVYQHRTGAVLGGHAIKILGWGEENSTPYWLAANSWNNDWGDKG 306
[Close]
BLAST of Cathepsin B vs. Ensembl Cavefish
Match: TINAGL1 (tubulointerstitial nephritis antigen like 1 [Source:NCBI gene;Acc:103033458])

HSP 1 Score: 143.28 bits (360), Expect = 9.850e-38
Identity = 105/325 (32.31%), Postives = 154/325 (47.38%), Query Frame = 2 
Query:   89 LSFDLINYVNYAQTTWKAAPTTRFQSVS---DIRKVLGVMKDPNSFKLPQKKQLMSDM--IFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGE-YPTPKCKRNCQSGYPK--TYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXX--------XXXXXXXXKIIGWGIENN-----TPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVA 1000
            +  D+I+ VN     W+A+  ++F  ++    +R  LG  +   +     + Q+  D     P  F+A  +W     I E  DQ NC + WAF  AA  +DR  I S     P++S ++L+SC     G GC GG   GAW +    G+VT         C  ++ P+   H       C  +     + KR   +  P   TY ND       Y +S  E +IM EIM NGPV+A  +V+ DF  Y++G+Y+H              G H+V+I GWG E +       YW+ ANSW   WG++GYF+I RG NEC IE  ++ 
Sbjct:  141 MEADMIHAVNRGNYGWRASNYSQFWGMTLDEGLRYRLGTRRPSRAIMSMNEIQMNMDHNEHLPSYFNAAEKWPG--KIHEPLDQGNCAASWAFSTAAVASDRISIQSMGHMTPQLSPQNLISCDTRNQG-GCAGGRIDGAWWFLRRRGVVT-------EECYPFSAPQ---HTPAEVGRCMMQSRSVGRGKRQATARCPNSHTYNNDIFQSTPPYRLSTNEKEIMKEIMDNGPVQAILEVHEDFFTYKSGIYRHTNVNYHKAPQYRNHGTHSVRITGWGEERDYTGRTHKYWIAANSWGKNWGEDGYFRIARGENECEIEAFVIG 452
[Close]
BLAST of Cathepsin B vs. Ensembl Sea Lamprey
Match: ctsbb (cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1])

HSP 1 Score: 357.451 bits (916), Expect = 2.067e-122
Identity = 183/337 (54.30%), Postives = 229/337 (67.95%), Query Frame = 2 
Query:    8 LFFTVLLLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLG-VMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 1015
            +   +LLL  A          +P+  PLS  + NYVN   TTW+A       SV D+R++ G V+  P   KLP +   +S  + PDSFDAR +W  C +I E+RDQ +CGSCWAFGA  AM+DR+CIHS     P +S+EDL+SCC E CG GC+GG+P+ AW++W + G+VTGG+Y S  GC+ Y+   C HHV G  P C+GE PTPKC   C  GY   Y+ DK FGK +Y+I + ES I  EI  NGPVEA F VYADFP Y++GVYQHVAG  LGGHA+KI+GWG+E   PYWL+ANSWN  WGD+GYFKI+RG NECGIEDEIVAG+P L
Sbjct:    1 MLRVLLLLCVACTTRLVAGRSVPLLPPLSKYMANYVNTLGTTWQAGHAFNGASVEDVRRLCGTVLGGP---KLPTRTHKVSQSL-PDSFDARTQWPNCPTIGELRDQGSCGSCWAFGAVEAMSDRFCIHSKGQVNPHVSAEDLLSCCDE-CGMGCDGGYPSQAWNFWTSTGLVTGGQYSSGQGCRPYSIKPCEHHVNGSRPPCSGEGPTPKCVHECVPGYTPHYKADKYFGKKAYNIDSDESQIKQEIFDNGPVEAAFTVYADFPQYKSGVYQHVAGEELGGHAIKILGWGVEGGVPYWLVANSWNADWGDHGYFKILRGSNECGIEDEIVAGLPSL 332
[Close]
BLAST of Cathepsin B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010475.1 (pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 gene:ENSPMAG00000009483.1 transcript:ENSPMAT00000010475.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 86.6557 bits (213), Expect = 2.119e-19
Identity = 75/281 (26.69%), Postives = 120/281 (42.70%), Query Frame = 2 
Query:  155 RFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIF--PDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDV-YADFPNYRTGVYQXXXXXXXXXXXXKIIGWGI-ENNTPYWLIANSWNPTWGDNGYFKIIRGVNE-CGI 982
             FQ V     +LG      + K P+    M+   F  P+S D    W +   + ++++Q +CGSCW+F    ++  ++   +       +S ++LV C   +   GCNGG    A++Y   +G +   E               S+  KG    C  +   PK K    +GY +    D             E  +M  +   GPV    D   A F +Y +G+Y+         HAV ++G+G+ E    +WL+ NSW  TWG+ GY ++ R  N  CGI
Sbjct:   46 EFQQV-----MLGFRGWNGTSKAPRGATFMAPAFFEAPESVD----WRKQGYVTDIKNQGDCGSCWSFSTTGSLEGQHKRKTGVLVS--LSEQNLVDCSSTEGNHGCNGGLMINAFNYIKKNGGIDSEE---------------SYPYKGQVETCKYD---PKNKAAEVTGYVEIPEGD-------------EEALMNAVASVGPVSVAIDASLASFQSYGSGIYKDAMCSHHIDHAVLVVGYGVDEMGQKFWLVKNSWGVTWGEQGYVRMARDDNNLCGI 284
[Close]
BLAST of Cathepsin B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006499.1 (pep scaffold:Pmarinus_7.0:GL477089:42202:47941:1 gene:ENSPMAG00000005817.1 transcript:ENSPMAT00000006499.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 85.8853 bits (211), Expect = 7.211e-19
Identity = 73/263 (27.76%), Postives = 112/263 (42.59%), Query Frame = 2 
Query:  224 PQKKQLMSDMIFPDSFDA--RLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPK-TYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDV-YADFPNYRTGVY-QXXXXXXXXXXXXKIIGWGI----ENNTPYWLIANSWNPTWGDNGYFKIIRG-VNECGI 982
            P K    S  + P +++A   ++W +   + EV+DQ  CGSCWAF    A+  ++           +S ++LV C   +   GC GG    A+ Y   +G +            + A+P         Y    G+    KC  +     PK    ND  F   +   S  E  + + +   GPV    D  +  F  Y++GVY +         H V ++G+G+    EN   YW++ NSW+P WGD GY  + R   N CGI
Sbjct:  101 PHKVSKGSTFLVPQNYEAPPTVDWRDKGLVTEVKDQGECGSCWAFSTTGALEGQHMRKVGQLVS--LSEQNLVDCSRAEGNQGCGGGLMDQAFQYVKDNGGID----------SEAAYP---------YTGTDGD----KCHYD-----PKFNSANDTGFVDVT---SGDEKALKIAVASVGPVSVAIDASHESFQFYQSGVYFEPDCSSQDLDHGVLVVGYGVKGTGENGKKYWIVKNSWSPKWGDEGYVLMARNKKNHCGI 330
[Close]
BLAST of Cathepsin B vs. Ensembl Sea Lamprey
Match: ctsc (cathepsin C [Source:ZFIN;Acc:ZDB-GENE-030619-9])

HSP 1 Score: 86.6557 bits (213), Expect = 1.056e-18
Identity = 81/322 (25.16%), Postives = 135/322 (41.93%), Query Frame = 2 
Query:  101 LINYVNYAQTTWKAA---PTTRFQSVSDIRKVLG---VMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGC-QDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXK------IIGWGIE------NNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMP 1009
             ++ +N AQ++W+A       R      +R+  G   ++ +         +      + P ++D R +      +  VRDQ  CGSC++F + A +  R  I SN T +P  S + +VSC       GC+GGFP            +  G++    G  ++  +P      K +  +       P C R         Y   +      +  +  E  + LE++ NGP+  GF VY DF  Y+ G+Y H           +      ++G+G +         P+W++ NSW   WG+ GYF+I RG +EC  E   +A  P
Sbjct:  174 FVHAINSAQSSWRAGRYLDMERRPMEEIVRRSGGTGSIIPNRPRAAAASDETRRRAAVLPAAWDWR-DVRGVSYVSPVRDQGACGSCYSFASMAMLEARVRILSNNTQQPVFSPQHIVSC--SPYSQGCDGGFP-----------YLIAGKFAQDFGVIEESCYPYIGQDSKCLPKD-------PSCLR---------YYTARYHYVGGFYGACSEELMRLELVENGPLAIGFQVYDDFMAYQGGIYHHTGLRDQFNPFEETNHAVLLVGYGTDAAGPEGTGEPFWIVKNSWGEGWGEGGYFRIRRGNDECAFESIAMAATP 465
[Close]
BLAST of Cathepsin B vs. Ensembl Sea Lamprey
Match: ctsf (cathepsin F [Source:ZFIN;Acc:ZDB-GENE-030131-9831])

HSP 1 Score: 83.9593 bits (206), Expect = 1.467e-18
Identity = 65/256 (25.39%), Postives = 111/256 (43.36%), Query Frame = 2 
Query:  224 PQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGV---YQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGI 982
            P++  L    I P       +W +  ++ EV++Q  CGSCWAF     +  ++ I   +     +S ++LV C  +K   GC GG    A+         T  E G  +   DY++       KG    C               G+ +     + +   S SIS+ E ++   ++ +GP+    +       Y+ G+   ++ +       HAV I+G+G E   P+W+I NSW   WG+ GY+++ RG   CG+
Sbjct:   59 PREVGLRQAQIPPGPIPPAFDWRDRGAVTEVKNQGECGSCWAFSVTGNIEGQWAIKKGSLLS--LSEQELVDC--DKLDYGCGGGLQMNAYK--------TIQELGGLMTESDYSY-------KGDMEQC---------------GFSQA--KVRAYINGSVSISSDEDEMAAWLVKHGPISIALNALG-MQFYKHGIAHPWKILCWSWELNHAVLIVGYGTEKGVPFWIIKNSWGVGWGEEGYYRVFRGDGVCGL 277
[Close]
BLAST of Cathepsin B vs. Ensembl Nematostella
Match: EDO34588 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNX0])

HSP 1 Score: 311.997 bits (798), Expect = 1.846e-105
Identity = 149/252 (59.13%), Postives = 184/252 (73.02%), Query Frame = 2 
Query:  260 PDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 1015
            PD FD+R +W  C +I+EVRDQ  CGSCWAFGA  AM+DRYCI S     P IS+EDL+SCC E CG GCNGG+P  AW +W + G+VTGG+Y SH GCQ Y    C HHV G    C G+ PTPKC+R C++GY  +Y +DK FG+++YS+ +  ++I  EIM NGPVE  F VYADFP Y++GVYQH +G  LGGHA+KI+GWG EN TPYWL+ANSWN  WGD G+FKI RG +ECGIE  IV G+P+ 
Sbjct:    5 PDHFDSREQWPHCPTIKEVRDQGACGSCWAFGAVEAMSDRYCIKSEGKVMPHISAEDLLSCC-ETCGMGCNGGYPESAWDHWKSKGLVTGGQYDSHKGCQPYKIAACDHHVVGKLKPCKGDSPTPKCERKCEAGYNVSYSDDKHFGQSAYSVRSDPAEIQKEIMTNGPVEGAFTVYADFPTYKSGVYQHTSGSALGGHAIKILGWGEENGTPYWLVANSWNSDWGDEGFFKIKRGNDECGIESGIVGGLPKF 255
[Close]
BLAST of Cathepsin B vs. Ensembl Nematostella
Match: EDO38122 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDR5])

HSP 1 Score: 180.259 bits (456), Expect = 2.039e-53
Identity = 119/320 (37.19%), Postives = 170/320 (53.12%), Query Frame = 2 
Query:   71 IPI--HSPLSFDLINYVNYAQTTWKAAPTTRFQSVS--DIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESD-IMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 1015
            IPI     +S DL++ +N     W+A    +F++++    + +LG         LP + ++      P++FDAR +W    SI  +R+Q  CGSCWAFGA+  ++DR+ I S       +S++ LV C  +    GC+GG+P  AW+Y V  G++T   YG +   Q                 C     T  C    Q G    + +     K++Y +  K  + I  +IM NGPVEA F ++ DF  YR+G+Y H  G  LGGHA+KI+GWG E+N  YWL ANSW   WG  GYFKI RG +ECGIED + AG+P L
Sbjct:   17 IPISKEKVISRDLVDKINTLNVGWEATLYPQFENLTFESAKSMLGSRGAWPEGSLPPEIEVRVAENIPENFDARKQWPG--SIHPIRNQGQCGSCWAFGASEVLSDRFAIASKNQIYVTLSAQQLVDC--DLDNSGCSGGWPINAWNYMVKTGLLTEQCYGPYYAKQ---------------YTCRLTANTTDCP--WQPGVKARFYH----AKSAYKLPAKNVEAIQTDIMNNGPVEADFTIFQDFYAYRSGIYVHATGKQLGGHAIKILGWGTEDNVDYWLCANSWGANWGIQGYFKIRRGTDECGIEDGLAAGLPLL 311
[Close]
BLAST of Cathepsin B vs. Ensembl Nematostella
Match: EDO42751 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0K3])

HSP 1 Score: 87.0409 bits (214), Expect = 2.105e-19
Identity = 69/245 (28.16%), Postives = 103/245 (42.04%), Query Frame = 2 
Query:  257 FPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGV---YQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGI 982
             P+S D    W +   +  V++Q +CGSCWAF     +  +Y I +       +S ++LV C  +    GC GG P+ A+            + G      DY +       KG    C       K   N                 +S  IS  E +I   +  NGP+  G +  A    Y  G+   ++         H V I+G+G++N TPYW+I NSW P+WG+ GY+ I RG   CG+
Sbjct:   63 IPESVD----WRDKGVVTPVKNQGSCGSCWAFSTTGNIEGQYAIKTGKLV--SLSEQELVDC--DTIDKGCEGGLPSNAYKQIE--------KLGGLESESDYPY-------KGADSKCKFNKAEVKVTIN-----------------SSVVISKDEKEIAAWLAKNGPISIGINANA-MQFYMGGIAHPWKIFCNPSSLNHGVLIVGYGVKNGTPYWIIKNSWGPSWGEKGYYLIYRGGGCCGL 266
[Close]
BLAST of Cathepsin B vs. Ensembl Nematostella
Match: EDO37120 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGN5])

HSP 1 Score: 84.3445 bits (207), Expect = 1.270e-18
Identity = 68/250 (27.20%), Postives = 100/250 (40.00%), Query Frame = 2 
Query:  221 LPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQ---SNCGSCWAFGAAAAMTDRYCIHSNATY-KPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKII 958
            +P +   M+ +  P SFD R + +        R+Q     CGSCWA G  +AM DR  I     +    +S + ++ C        C+GG   G + Y  T GI           C +Y       +V              KC      G      N + +    Y   N    +M EI   GP+  G     +  NY  GVY+         H V ++GWG+EN   YW++ NSW   WG+ G+F+I+
Sbjct:    1 MPHEYLNMAKL--PTSFDWR-DVNGTNYASTTRNQHIPQYCGSCWAHGTTSAMADRINILRKGKWPSAYLSVQHVLDCAN---AGTCHGGGMLGVYQYAQTHGI-------PDETCNNYQAKDQDCNVFN------------KCGTCTTFGKCHVIENYRLWKAEEYGNVNGREKMMAEIFARGPIACGIMATPNLDNYTKGVYKEHNTSPEINHIVSVMGWGVENGEEYWVVRNSWGTPWGEEGFFRIV 225
[Close]
BLAST of Cathepsin B vs. Ensembl Nematostella
Match: EDO46465 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPY5])

HSP 1 Score: 81.6481 bits (200), Expect = 2.620e-17
Identity = 71/252 (28.17%), Postives = 103/252 (40.87%), Query Frame = 2 
Query:  242 MSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYK-PRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVT-DGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDV-YADFPNYRTGVYQXXXXXXXXXXXXKI-IGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGV-NECGI 982
            +S++  P    A ++W +   +  V++Q  CGSCWAF +  ++  +   H   T K   +S ++LV C  +   +GC GG    A+ Y    DGI T   Y        Y       H K   P   G   T         GY    R               E D+   +   GP+    D  ++ F  Y+TGVY              + +G+G E+   YWL+ NSW   WG NGY K+ R   N+CGI
Sbjct:  104 LSNVQLP----AEVDWRDKGFVTAVKNQGQCGSCWAFSSTGSLEGQ---HFRKTGKLVSLSEQNLVDCSKKYGNNGCEGGLMDYAFKYIKNNDGIDTEQSY-------PYTARDGQCHFK---PGSVGATVT---------GYTDVQRG-------------SEGDLQSAVATVGPISVAIDAGHSSFQLYKTGVYSEPDCSSTQLDHGVLAVGYGAEDGKDYWLVKNSWGEGWGMNGYIKMSRNKDNQCGI 316
[Close]
BLAST of Cathepsin B vs. Ensembl Medaka
Match: ctsba (cathepsin B [Source:NCBI gene;Acc:101160638])

HSP 1 Score: 350.132 bits (897), Expect = 7.162e-119
Identity = 176/315 (55.87%), Postives = 220/315 (69.84%), Query Frame = 2 
Query:   74 PIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVM-KDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEY-PTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            P   PLS D++NY+N   TTWKA    +    S ++K+ G M K P   KLP   Q   D+  P  FDAR +W  C +++E+RDQ +CGSCWAFGAA A++DR CIHSNA     ISSEDL++CC E CG GCNGG+PT AW +W  +G+VTGG Y SHVGC+ Y  P C HHV G  P CTGE   TP+C   C+SGY  +Y+ DK +GKTSYS+   E+ I  EI  NGPVE  F VY DFP Y++GVYQHV+G ++GGHA+KI+GWG+E+  PYWL ANSWN  WGDNGYFKI+RG + CGIE E+VAG+P+
Sbjct:   20 PRFHPLSSDMVNYINKLNTTWKAGHNFKNADYSYVQKLCGTMLKGP---KLPIMVQYAGDVKLPTEFDARAQWPNCPTLKEIRDQGSCGSCWAFGAAEAISDRVCIHSNARVSVEISSEDLLTCC-ESCGMGCNGGYPTAAWDFWTKEGLVTGGLYDSHVGCRPYTIPPCEHHVNGTRPPCTGEGGDTPQCINQCESGYTPSYKKDKHYGKTSYSVEANENQIQTEIYKNGPVEGAFMVYEDFPMYKSGVYQHVSGSLIGGHAIKILGWGVEDGVPYWLCANSWNTDWGDNGYFKILRGSDHCGIESEVVAGIPK 330
[Close]
BLAST of Cathepsin B vs. Ensembl Medaka
Match: ctsba (cathepsin B [Source:NCBI gene;Acc:101160638])

HSP 1 Score: 350.517 bits (898), Expect = 9.926e-119
Identity = 176/315 (55.87%), Postives = 220/315 (69.84%), Query Frame = 2 
Query:   74 PIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVM-KDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEY-PTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQ 1012
            P   PLS D++NY+N   TTWKA    +    S ++K+ G M K P   KLP   Q   D+  P  FDAR +W  C +++E+RDQ +CGSCWAFGAA A++DR CIHSNA     ISSEDL++CC E CG GCNGG+PT AW +W  +G+VTGG Y SHVGC+ Y  P C HHV G  P CTGE   TP+C   C+SGY  +Y+ DK +GKTSYS+   E+ I  EI  NGPVE  F VY DFP Y++GVYQHV+G ++GGHA+KI+GWG+E+  PYWL ANSWN  WGDNGYFKI+RG + CGIE E+VAG+P+
Sbjct:   42 PRFHPLSSDMVNYINKLNTTWKAGHNFKNADYSYVQKLCGTMLKGP---KLPIMVQYAGDVKLPTEFDARAQWPNCPTLKEIRDQGSCGSCWAFGAAEAISDRVCIHSNARVSVEISSEDLLTCC-ESCGMGCNGGYPTAAWDFWTKEGLVTGGLYDSHVGCRPYTIPPCEHHVNGTRPPCTGEGGDTPQCINQCESGYTPSYKKDKHYGKTSYSVEANENQIQTEIYKNGPVEGAFMVYEDFPMYKSGVYQHVSGSLIGGHAIKILGWGVEDGVPYWLCANSWNTDWGDNGYFKILRGSDHCGIESEVVAGIPK 352
[Close]
BLAST of Cathepsin B vs. Ensembl Medaka
Match: ctsbb (cathepsin B [Source:NCBI gene;Acc:101165526])

HSP 1 Score: 320.087 bits (819), Expect = 4.723e-107
Identity = 164/317 (51.74%), Postives = 210/317 (66.25%), Query Frame = 2 
Query:   62 KAHIPIHSPLSFDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLG-VMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMP 1009
            +  +P+   LS ++I++VN   TTW A      +  S ++ + G ++K P   KLP+    +  +  PDSFD R +W  C +++++RDQ NCGSCWAFGAA A++DR CI S       IS+EDL++CC E CG GC GGFP+ AW +W   G+VTGG + S VGC+ Y    C HHV G  P C GE  TPKC   C +GY  +Y  DK FG+ SYSI +++  IM E+  NGPVEA F VYADF  Y+ GVYQHV G +LGGHAVKI+GWG EN TPYWL+ANSWN  WGD G+FKI RG +ECGIE E+VAG P
Sbjct:   19 RPQLPL---LSLEMIDFVNKLNTTWTAGQNFHNKDSSFVKGLCGTILKGP---KLPELAHDVEGIKLPDSFDPREQWPNCPTLKQIRDQGNCGSCWAFGAAEAISDRICIQSGGKISLEISAEDLLTCCDE-CGMGCFGGFPSAAWEFWTNKGLVTGGLFDSKVGCRPYTLAPCEHHVNGSRPPCQGEVETPKCVTQCNNGYSLSYPKDKHFGQRSYSIPSQQEQIMTELYKNGPVEAAFSVYADFLLYKNGVYQHVTGDMLGGHAVKILGWGEENGTPYWLVANSWNSDWGDKGFFKIKRGNDECGIESEMVAGAP 328
[Close]
BLAST of Cathepsin B vs. Ensembl Medaka
Match: TINAGL1 (tubulointerstitial nephritis antigen like 1 [Source:NCBI gene;Acc:101158958])

HSP 1 Score: 144.436 bits (363), Expect = 3.482e-38
Identity = 109/326 (33.44%), Postives = 153/326 (46.93%), Query Frame = 2 
Query:   89 LSFDLINYVNYAQTTWKAAPTTRFQSVS---DIRKVLGVMKDPNSFKLPQKKQLMSDMI---FPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYA-FPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTY--RNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXX--------XXXXKIIGWGIENN---TP--YWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVA 1000
            +  D+I+ VN     WKAA  ++F  +S    IR  LG  +   +     + Q+  D      P  F++  +W     I E  DQ NC + WAF  AA  +DR  I S     P++S ++L+SC     G GC GG   GAW Y    G+VT   Y      Q  A   +C    + +           + KR      P TY   ND       Y +S+ E +IM EIM NGPV+A  +V+ DF  Y+ G+Y+H                H+V+I GWG + +   TP  YW+ ANSW   WG+NG+F+I RG NEC IE  ++ 
Sbjct:  140 IEADIIHAVNRGNYGWKAANYSQFFGMSLDEGIRYRLGTQRPSRTVMNMNEIQMKMDPQNDHLPRYFNSSEKWPN--KIHEPLDQGNCAASWAFSTAAVASDRISIQSMGHMTPQLSPQNLISCDTRNQG-GCAGGRIDGAWWYLRRRGVVTENCYPYQPPQQAPAEVGRCMMQSRAV----------GRGKRQATQRCPNTYNYHNDIYQSTPPYKLSSNEKEIMKEIMENGPVQAIMEVHEDFFVYKNGIYKHTDVSSTKPPQYRKHGTHSVRITGWGEDKDYDGTPRKYWIAANSWGKNWGENGFFRIARGANECEIEAFVIG 452
[Close]
BLAST of Cathepsin B vs. Ensembl Medaka
Match: ctsc (cathepsin C [Source:NCBI gene;Acc:101170449])

HSP 1 Score: 108.612 bits (270), Expect = 1.925e-25
Identity = 92/321 (28.66%), Postives = 148/321 (46.11%), Query Frame = 2 
Query:   98 DLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQ---LMSDMI-----FPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQF-GKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXX------XXXXXXXKIIGWGIENNT--PYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMP 1009
            D I+ +N  Q +W+AAP    +  + ++++      P S ++P + +   + +D+       P+S+D R        +  VR+Q+ CGSC++F     +  R  + +N +  P  S + +VSC   +   GC+GGFP     Y    GIV           ++  FP  +       P            +NC   Y   Y+    F G  S      E  +M E++ +GP+   F+VY DF +Y  G+Y H           L  HAV ++G+G  + T   YW++ NSW  +WG+NG+F+I RG +EC IE   VA  P
Sbjct:  166 DFIHLINSVQKSWRAAPHPEHEMYT-LQELHYRAGGPAS-RVPVRVRPAPVTADLAKVAAALPESWDWR-NVGGVNFVSPVRNQAACGSCYSFATMGMLEARVRVLTNNSQTPVFSPQQVVSC--SEYSQGCDGGFPYLIGKYSQDFGIV-----------EESCFPYIAKDSPCGVP------------QNCGRAYTAEYKYVGGFYGGCS------EMAMMKELVHHGPMAVAFEVYPDFMHYAGGIYHHTGLADPFNPFELTNHAVLLVGYGRCHKTGEKYWIVKNSWGTSWGENGFFRIRRGSDECSIESIAVAATP 452
[Close]
BLAST of Cathepsin B vs. Planmine SMEST
Match: SMESG000048415.1 (SMESG000048415.1)

HSP 1 Score: 605.134 bits (1559), Expect = 0.000e+0
Identity = 302/307 (98.37%), Postives = 302/307 (98.37%), Query Frame = 2 
Query:   95 FDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 1015
            F  IN V  AQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQHVAGGVLGGHAVKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL
Sbjct:    9 FKEINTVFQAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQHVAGGVLGGHAVKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 315
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BLAST of Cathepsin B vs. Planmine SMEST
Match: SMESG000048414.1 (SMESG000048414.1)

HSP 1 Score: 605.134 bits (1559), Expect = 0.000e+0
Identity = 302/307 (98.37%), Postives = 302/307 (98.37%), Query Frame = 2 
Query:   95 FDLINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 1015
            F  IN V  AQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQHVAGGVLGGHAVKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL
Sbjct:    9 FKEINTVFQAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQHVAGGVLGGHAVKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 315
[Close]
BLAST of Cathepsin B vs. Planmine SMEST
Match: SMESG000048413.1 (SMESG000048413.1)

HSP 1 Score: 514.612 bits (1324), Expect = 0.000e+0
Identity = 243/347 (70.03%), Postives = 291/347 (83.86%), Query Frame = 2 
Query:    8 LFFTVLLLVFAGAANCHR----------KAHIPIHSPLSFDLINYVNY-AQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXXKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 1015
            +     +L+F+   NC R          K  IPIH+PLSFDLINYVNY AQTTWKA PTTRFQ+VSDIRKVLGV+KDPN+FKLP+K   ++ +  P SFD+R++W +C+SI E+RDQSNCGSCWAFGA  AMTDRYCIHSN T  PRIS+EDL++CCG +CGDGCNGGFP+GAW +WV+ G+VTGGEYG+H+GCQDYAFPKCSHHV G YPNCTGE+PTPKCK+ CQ+GY KTY+ DKQFGKTSYS+  +E +IM EI+ NGPVEA F VYADFPNY++GVYQHV+G +LGGHA+KI+GWG+ENNTPYWL+ANSWNPTWGD GYFKI +G NECGIEDE+VAG+P+L
Sbjct:    3 IILISFVLLFS-LVNCDRTKWESLTKSVKGQIPIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 348
[Close]
BLAST of Cathepsin B vs. Planmine SMEST
Match: SMESG000077197.1 (SMESG000077197.1)

HSP 1 Score: 136.346 bits (342), Expect = 1.609e-35
Identity = 108/326 (33.13%), Postives = 157/326 (48.16%), Query Frame = 2 
Query:  101 LINYVNYAQTTWKAAPTTRF--QSVSDIRKVLG----VMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXX-------------XXXXXXXKIIGWGIENNTP----YWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMP 1009
            L++ +N     W A     F  +++ DI ++ G    +   P S  + +  +L ++  FP SFD R   +    +  VR Q +CGSC++F +A  +  RY I SN T KP +S +D+V C       GCNGGFP            +  G+Y    G  D    KC+ + KG    C+         +NC+  Y   Y    Q+    Y  +N E  + +E++ NGP+  GF+VY+DF  Y+ G+Y HV                 L  HAV ++G+G    TP    YW++ NSW P WG+ GYFKI RG +ECGIE   VA  P
Sbjct:  160 LVDLINEKNVGWTAKDYPEFHNRTLHDIIQMSGGFNSLHNRPKSAPVTKIVRLTAEK-FPKSFDWR-NVNGVNFVSPVRSQGHCGSCYSFASAGMLEARYRIKSNNTIKPILSPQDVVEC--SPYSQGCNGGFP-----------YLIAGKYAQDFGMAD---EKCNPY-KGKDGKCS-------TIKNCKRYYATKY----QYLGGFYGSTN-EPLMRMELVINGPIAVGFEVYSDFRQYKNGIYHHVFKADNLMTSRFGFNPFELTNHAVLVVGYG---ETPAGEKYWIVKNSWGPKWGEGGYFKIRRGNDECGIESLAVASQP 451
[Close]
BLAST of Cathepsin B vs. Planmine SMEST
Match: SMESG000077202.1 (SMESG000077202.1)

HSP 1 Score: 116.701 bits (291), Expect = 1.895e-28
Identity = 100/349 (28.65%), Postives = 146/349 (41.83%), Query Frame = 2 
Query:   59 RKAHIPIHSPLSFD---------LINYVNYAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKK-------QLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQXXXXXXXXXXXX-------------KIIGWG-IENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 1015
            +  HIP  +  + +         ++N +N     W A     F   +  + V   M    S KL + K        L S    P SFD R   +    +  VR+Q  CGSC++F +A  +  RY I SN T  P +S +D+V C       GC GGFP            +  G++    G    A   C+ +         GE       +NCQ  Y   Y+    F    Y  +N E  + +E++ NGP+  GF+VY DF +Y++GVY H         +               ++G+G       +W + NSW   WG+NGYF+I R  +ECGIE   VA  P L
Sbjct:  137 KHVHIPQSNIFALNSLLYGSQKHIVNTINNQNIGWIAKDYPEFHEKTLYQIVR--MAGGFSSKLHRPKPAPVTEYHLNSVKYIPKSFDWR-NVNGVNYVSPVRNQGGCGSCYSFASAGMLEARYRIKSNNTISPILSPQDVVEC--SPYSQGCEGGFP-----------YLIAGKFAEDFGM---AQESCNPY--------KGEDGKCSTTKNCQRYYATKYKYIGGF----YGATN-EPLMRMELVRNGPIAVGFEVYDDFMSYQSGVYHHDFKTRKLTASKFGFNPFELTNHAVLVVGYGETATGEKFWTVKNSWGSGWGENGYFRIRRANDECGIESLGVASEPIL 453
The following BLAST results are available for this feature:
BLAST of Cathepsin B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CTSB5.480e-12153.19cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527][more]
CTSB5.480e-12153.19cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527][more]
CTSB5.480e-12153.19cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527][more]
CTSB5.480e-12153.19cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527][more]
CTSB5.480e-12153.19cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527][more]
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BLAST of Cathepsin B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
F57F5.11.682e-9748.77pep chromosome:WBcel235:V:12003028:12004600:1 gene... [more]
cpr-64.740e-9746.69Cathepsin B-like cysteine proteinase 6 [Source:Un... [more]
cpr-66.929e-9649.84Cathepsin B-like cysteine proteinase 6 [Source:Un... [more]
cpr-67.089e-9649.84Cathepsin B-like cysteine proteinase 6 [Source:Un... [more]
cpr-58.926e-9547.73Cathepsin B-like cysteine proteinase 5 [Source:Un... [more]
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BLAST of Cathepsin B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CtsB17.283e-10147.67gene:FBgn0030521 transcript:FBtr0346091[more]
CtsB17.283e-10147.67gene:FBgn0030521 transcript:FBtr0073838[more]
Swim3.178e-3333.59gene:FBgn0034709 transcript:FBtr0071785[more]
Swim3.178e-3333.59gene:FBgn0034709 transcript:FBtr0071784[more]
CG48474.168e-1826.43gene:FBgn0034229 transcript:FBtr0086934[more]
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BLAST of Cathepsin B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsba2.287e-11252.70cathepsin Ba [Source:ZFIN;Acc:ZDB-GENE-040426-2650... [more]
ctsbb4.315e-10651.46cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1][more]
ctsba4.509e-8449.25cathepsin Ba [Source:ZFIN;Acc:ZDB-GENE-040426-2650... [more]
tinagl13.905e-3531.68tubulointerstitial nephritis antigen-like 1 [Sourc... [more]
ctsc5.171e-2728.75cathepsin C [Source:ZFIN;Acc:ZDB-GENE-030619-9][more]
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BLAST of Cathepsin B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsb1.085e-11952.11cathepsin B [Source:NCBI gene;Acc:394833][more]
ctsb2.616e-11351.39cathepsin B [Source:NCBI gene;Acc:394833][more]
ctsb5.423e-10857.25cathepsin B [Source:NCBI gene;Acc:394833][more]
ctsb6.474e-10750.47cathepsin B [Source:NCBI gene;Acc:394833][more]
TINAGL14.989e-3431.35tubulointerstitial nephritis antigen-like 1 [Sourc... [more]
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BLAST of Cathepsin B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ctsb9.534e-12054.14cathepsin B [Source:MGI Symbol;Acc:MGI:88561][more]
Tinagl12.317e-3532.10tubulointerstitial nephritis antigen-like 1 [Sourc... [more]
Tinagl12.317e-3532.10tubulointerstitial nephritis antigen-like 1 [Sourc... [more]
Tinagl12.317e-3532.10tubulointerstitial nephritis antigen-like 1 [Sourc... [more]
Tinagl12.496e-3332.37tubulointerstitial nephritis antigen-like 1 [Sourc... [more]
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BLAST of Cathepsin B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P83205|CATB_SHEEP2.320e-12454.10Cathepsin B OS=Ovis aries OX=9940 GN=CTSB PE=1 SV=... [more]
sp|Q4R5M2|CATB_MACFA1.848e-12154.95Cathepsin B OS=Macaca fascicularis OX=9541 GN=CTSB... [more]
sp|P00787|CATB_RAT1.951e-12154.78Cathepsin B OS=Rattus norvegicus OX=10116 GN=Ctsb ... [more]
sp|A1E295|CATB_PIG2.842e-12152.69Cathepsin B OS=Sus scrofa OX=9823 GN=CTSB PE=1 SV=... [more]
sp|Q5R6D1|CATB_PONAB4.047e-12154.95Cathepsin B OS=Pongo abelii OX=9601 GN=CTSB PE=2 S... [more]
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BLAST of Cathepsin B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267EBJ75.364e-13558.93Pept_C1 domain-containing protein OS=Macrostomum l... [more]
A0A1I8HY668.119e-13558.93Pept_C1 domain-containing protein OS=Macrostomum l... [more]
A0A1I8I7B05.185e-13258.28Pept_C1 domain-containing protein OS=Macrostomum l... [more]
A0A369SCR61.864e-13159.47Cathepsin B OS=Trichoplax sp. H2 OX=287889 GN=Tris... [more]
B3S1Y31.864e-13159.47Pept_C1 domain-containing protein OS=Trichoplax ad... [more]
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BLAST of Cathepsin B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsbb3.211e-10952.88cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1][more]
ctsba4.874e-10451.72cathepsin Ba [Source:ZFIN;Acc:ZDB-GENE-040426-2650... [more]
ctsbb1.286e-10250.80cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1][more]
ctsbb8.385e-9652.08cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1][more]
TINAGL19.850e-3832.31tubulointerstitial nephritis antigen like 1 [Sourc... [more]
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BLAST of Cathepsin B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsbb2.067e-12254.30cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1][more]
ENSPMAT00000010475.12.119e-1926.69pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 ... [more]
ENSPMAT00000006499.17.211e-1927.76pep scaffold:Pmarinus_7.0:GL477089:42202:47941:1 g... [more]
ctsc1.056e-1825.16cathepsin C [Source:ZFIN;Acc:ZDB-GENE-030619-9][more]
ctsf1.467e-1825.39cathepsin F [Source:ZFIN;Acc:ZDB-GENE-030131-9831][more]
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BLAST of Cathepsin B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cathepsin B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO345881.846e-10559.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO381222.039e-5337.19Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO427512.105e-1928.16Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO371201.270e-1827.20Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO464652.620e-1728.17Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cathepsin B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsba7.162e-11955.87cathepsin B [Source:NCBI gene;Acc:101160638][more]
ctsba9.926e-11955.87cathepsin B [Source:NCBI gene;Acc:101160638][more]
ctsbb4.723e-10751.74cathepsin B [Source:NCBI gene;Acc:101165526][more]
TINAGL13.482e-3833.44tubulointerstitial nephritis antigen like 1 [Sourc... [more]
ctsc1.925e-2528.66cathepsin C [Source:NCBI gene;Acc:101170449][more]
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BLAST of Cathepsin B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000048415.10.000e+098.37SMESG000048415.1[more]
SMESG000048414.10.000e+098.37SMESG000048414.1[more]
SMESG000048413.10.000e+070.03SMESG000048413.1[more]
SMESG000077197.11.609e-3533.13SMESG000077197.1[more]
SMESG000077202.11.895e-2828.65SMESG000077202.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010459 ID=SMED30010459|Name=Cathepsin B|organism=Schmidtea mediterranea sexual|type=transcript|length=1266bp
TTCCGATCTCTTTTTTACTGTTTTATTACTGGTATTTGCAGGGGCTGCCA
ACTGCCACAGGAAGGCCCATATTCCTATTCATTCACCACTCTCATTTGAT
CTAATTAATTATGTAAATTATGCTCAGACAACATGGAAAGCTGCTCCTAC
AACTCGATTTCAATCTGTCTCGGATATACGAAAAGTCCTAGGTGTTATGA
AAGATCCAAATAGTTTTAAGCTTCCTCAGAAAAAGCAATTGATGAGCGAT
ATGATTTTCCCAGACTCATTCGATGCAAGATTAGAGTGGTCGGAATGCGA
ATCAATTCGTGAAGTTCGAGATCAAAGTAATTGTGGATCGTGCTGGGCAT
TTGGAGCCGCTGCTGCAATGACTGATAGATACTGCATTCATTCCAATGCT
ACTTATAAACCACGGATAAGCTCTGAAGATCTCGTAAGCTGTTGTGGTGA
AAAATGCGGAGATGGATGCAATGGAGGATTCCCAACAGGAGCTTGGCATT
ACTGGGTCACAGATGGAATTGTAACTGGTGGAGAATATGGAAGTCATGTA
GGATGTCAAGACTATGCATTTCCAAAATGTTCCCATCATGTTAAGGGAAT
TTATCCAAATTGCACAGGAGAATATCCAACACCTAAATGTAAAAGAAACT
GCCAGTCTGGATATCCTAAAACATATCGAAATGACAAACAATTTGGAAAA
ACTTCCTACTCTATAAGTAATAAAGAATCCGACATTATGTTGGAGATCAT
GTTTAATGGACCTGTCGAAGCAGGTTTTGACGTTTATGCGGACTTCCCAA
ATTACAGAACTGGAGTTTATCAACACGTAGCTGGTGGAGTGCTTGGTGGA
CATGCTGTCAAGATAATCGGATGGGGAATAGAAAACAATACGCCATATTG
GTTGATAGCTAATTCCTGGAATCCAACTTGGGGAGATAATGGATATTTTA
AAATTATACGAGGCGTTAATGAATGCGGAATCGAAGACGAAATTGTAGCT
GGAATGCCGCAATTATAAAAGAACAATAGAATTAATGATTTATTTTATTA
AAAATACATTTTGTAAATTATTTATTAAATCTTCATGTTTTCTTAATTAG
TTTTATTTTCGTTAACATTCTGTGCTATCTTGGTCACCATAAAATTTAGA
CATTTGTAGACACAAAAGTTTTTAGACAAACATTTTTAGACATTTGTTGA
GACAATTTTTTTTTAGACAAAAATCTGTTTAGACAAATTTTGTGACAACT
TATGATAATTTTTCAA
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protein sequence of SMED30010459-orf-1

>SMED30010459-orf-1 ID=SMED30010459-orf-1|Name=SMED30010459-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=339bp
SDLFFTVLLLVFAGAANCHRKAHIPIHSPLSFDLINYVNYAQTTWKAAPT
TRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECE
SIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGE
KCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGI
YPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIM
FNGPVEAGFDVYADFPNYRTGVYQHVAGGVLGGHAVKIIGWGIENNTPYW
LIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR038765Papain-like_cys_pep_sf
IPR000668Peptidase_C1A_C
IPR012599Propeptide_C1A
IPR000169Pept_cys_AS
IPR025660Pept_his_AS
IPR025661Pept_asp_AS
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
GO:0050790regulation of catalytic activity
GO:0030574collagen catabolic process
GO:0030855epithelial cell differentiation
GO:0046697decidualization
GO:0046718viral entry into host cell
GO:0051603proteolysis involved in cellular protein catabolic process
GO:0097067cellular response to thyroid hormone stimulus
Vocabulary: molecular function
TermDefinition
GO:0008234cysteine-type peptidase activity
GO:0004197cysteine-type endopeptidase activity
GO:0005518collagen binding
GO:0008233peptidase activity
GO:0016787hydrolase activity
GO:0043394proteoglycan binding
Vocabulary: cellular component
TermDefinition
GO:0005576extracellular region
GO:0005615extracellular space
GO:0005730nucleolus
GO:0005739mitochondrion
GO:0005764lysosome
GO:0042470melanosome
GO:0043231intracellular membrane-bounded organelle
GO:0048471perinuclear region of cytoplasm
GO:0070062extracellular exosome
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000668Peptidase C1A, papain C-terminalPRINTSPR00705PAPAINcoord: 281..291
score: 47.46
coord: 105..120
score: 56.03
coord: 296..302
score: 65.02
IPR000668Peptidase C1A, papain C-terminalSMARTSM00645pept_c1coord: 83..332
e-value: 7.6E-96
score: 334.4
IPR000668Peptidase C1A, papain C-terminalPFAMPF00112Peptidase_C1coord: 84..331
e-value: 9.2E-65
score: 218.8
NoneNo IPR availableGENE3DG3DSA:3.90.70.10coord: 21..335
e-value: 7.1E-115
score: 385.9
NoneNo IPR availablePANTHERPTHR12411CYSTEINE PROTEASE FAMILY C1-RELATEDcoord: 30..329
NoneNo IPR availablePANTHERPTHR12411:SF606coord: 30..329
NoneNo IPR availableCDDcd02620Peptidase_C1A_CathepsinBcoord: 84..331
e-value: 9.36846E-141
score: 395.871
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..15
score: 0.615
IPR012599Peptidase C1A, propeptidePFAMPF08127Propeptide_C1coord: 27..66
e-value: 1.3E-10
score: 41.0
IPR025660Cysteine peptidase, histidine active sitePROSITEPS00639THIOL_PROTEASE_HIScoord: 279..289
IPR000169Cysteine peptidase, cysteine active sitePROSITEPS00139THIOL_PROTEASE_CYScoord: 105..116
IPR025661Cysteine peptidase, asparagine active sitePROSITEPS00640THIOL_PROTEASE_ASNcoord: 296..315
IPR038765Papain-like cysteine peptidase superfamilySUPERFAMILYSSF54001Cysteine proteinasescoord: 28..334