Innexin

Overview
NameInnexin
Smed IDSMED30010455
Length (bp)1707
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Innexin (SMED30010455) t-SNE clustered cells

Violin plots show distribution of expression levels for Innexin (SMED30010455) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Innexin (SMED30010455) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Innexin (SMED30010455) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30010455

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30010455h1SMcG0017745 NB.39.10esmed_ncbi_20240424PMID:17670787
Oviedo et al., 2007		whole organism asexual adult colorimetric in situ hybridization evidence
oral openingSMED30010455h1SMcG0017745 NB.39.10esmed_ncbi_20240424PMID:17670787
Oviedo et al., 2007		whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30010455h1SMcG0017745 SmedASXL_011897SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30010455h1SMcG0017745 dd_Smed_v4_9861_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30010455h1SMcG0017745 dd_Smed_v4_9861_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30010455h1SMcG0017745 dd_Smed_v6_9861_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 294.278 bits (752), Expect = 1.705e-94
Identity = 151/396 (38.13%), Postives = 231/396 (58.33%), Query Frame = 2 
Query:  341 HLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRM-DKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMN-YSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRHKSWQDNDNVRYLDMDCRRSV 1522
            H R DDD+VD+LNY  T  + F F  ++  + Y+G PIQCW P +F  AWE Y+EN+CWV NT+Y P+ +  PL   D+ ++ I YYQW P VLA++AL FYIPC++WR L++ +SG NV+ + QMA D   +  D  +  ++ IA +++  ++      +R    V G               C       ++  LY  +K+LY+ NV+LQ++++  FLGTD+ F+G  +L DL+NG EW  SGNFPRVT C+ + + LG  + + +QCVL +NMF EKI++FLWF+Y ++  ++  S   W++         KFIRKYL+  +    TD  +  KF    L  DGVF + +++ + G I+A +L V LW+ +       ND VR +  +   S+
Sbjct:   14 HPRVDDDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPLEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDALE-----IQREVTDVSGM--------------CVQKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRATDL--ATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNF-------NDRVRKIQFNSTESL 381
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 294.278 bits (752), Expect = 1.705e-94
Identity = 151/396 (38.13%), Postives = 231/396 (58.33%), Query Frame = 2 
Query:  341 HLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRM-DKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMN-YSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRHKSWQDNDNVRYLDMDCRRSV 1522
            H R DDD+VD+LNY  T  + F F  ++  + Y+G PIQCW P +F  AWE Y+EN+CWV NT+Y P+ +  PL   D+ ++ I YYQW P VLA++AL FYIPC++WR L++ +SG NV+ + QMA D   +  D  +  ++ IA +++  ++      +R    V G               C       ++  LY  +K+LY+ NV+LQ++++  FLGTD+ F+G  +L DL+NG EW  SGNFPRVT C+ + + LG  + + +QCVL +NMF EKI++FLWF+Y ++  ++  S   W++         KFIRKYL+  +    TD  +  KF    L  DGVF + +++ + G I+A +L V LW+ +       ND VR +  +   S+
Sbjct:   14 HPRVDDDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPLEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDALE-----IQREVTDVSGM--------------CVQKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRATDL--ATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNF-------NDRVRKIQFNSTESL 381
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 292.352 bits (747), Expect = 4.155e-93
Identity = 150/386 (38.86%), Postives = 227/386 (58.81%), Query Frame = 2 
Query:  341 HLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRM-DKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMN-YSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRHKSWQDNDNVR 1492
            H R DDD+VD+LNY  T  + F F  ++  + Y+G PIQCW P +F  AWE Y+EN+CWV NT+Y P+ +  PL   D+ ++ I YYQW P VLA++AL FYIPC++WR L++ +SG NV+ + QMA D   +  D  +  ++ IA +++  ++      +R    V G               C       ++  LY  +K+LY+ NV+LQ++++  FLGTD+ F+G  +L DL+NG EW  SGNFPRVT C+ + + LG  + + +QCVL +NMF EKI++FLWF+Y ++  ++  S   W++         KFIRKYL+  +    TD  +  KF    L  DGVF + +++ + G I+A +L V LW+ +       ND VR
Sbjct:   14 HPRVDDDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPLEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDALE-----IQREVTDVSGM--------------CVQKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRATDL--ATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNF-------NDRVR 371
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412])

HSP 1 Score: 276.174 bits (705), Expect = 3.258e-87
Identity = 141/373 (37.80%), Postives = 225/373 (60.32%), Query Frame = 2 
Query:  347 RFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRM-DKTSKLIGYYQWTPIVLAVQALMFYIPCLIWR-LLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKIL---NAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWN 1450
            R DDD+VD+LNY  T  +   F  ++  + Y+G PIQCW P  F  A E Y+EN+CWV NT++ P+  ++P  +  + ++ IGYYQW P +LA++AL+FY+PC++WR LL  +SG N++ ++QMA D   +  +I ++ +  +AR++   +     D + +  S      N +   NC  RHC     G ++  LY  +KVLY  NVLLQ +L+   LG++   +G  +L DL++  EW  +G FPRVT C+ + + LG  + + +QCVL +NMF EKI++FLWF+++  GI+T  +   W+L M        F+RKYL++L    A    D+    KFT N LR DGVF++ +++ + G +++ +L + LW 
Sbjct:   16 RLDDDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDEVQLTNIDRQGHSRSCFS---NLQLGANC-GRHC-----GCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQ 379
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412])

HSP 1 Score: 277.715 bits (709), Expect = 6.589e-87
Identity = 145/378 (38.36%), Postives = 227/378 (60.05%), Query Frame = 2 
Query:  347 RFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRM-DKTSKLIGYYQWTPIVLAVQALMFYIPCLIWR-LLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYID---TCIDR--NYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKIL---NAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWN 1450
            R DDD+VD+LNY  T  +   F  ++  + Y+G PIQCW P  F  A E Y+EN+CWV NT++ P+  ++P  +  + ++ IGYYQW P +LA++AL+FY+PC++WR LL  +SG N++ ++QMA D   +  +I ++ +  +AR++    T IDR  + R C  N           +   NC  RHC     G ++  LY  +KVLY  NVLLQ +L+   LG++   +G  +L DL++  EW  +G FPRVT C+ + + LG  + + +QCVL +NMF EKI++FLWF+++  GI+T  +   W+L M        F+RKYL++L    A    D+    KFT N LR DGVF++ +++ + G +++ +L + LW 
Sbjct:   90 RLDDDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDELTNIDRQGHSRSCFSN----------LQLGANC-GRHC-----GCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQ 451
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: shakB (gene:FBgn0085387 transcript:FBtr0309369)

HSP 1 Score: 88.5817 bits (218), Expect = 1.302e-18
Identity = 85/318 (26.73%), Postives = 136/318 (42.77%), Query Frame = 2 
Query:  302 VWKIAKLGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYA--------------PINNNLPLRMDKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGN----FPRVTFCE-VQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFY 1198
            V+   ++ R   SH++ D   V RL+   T  L   F   +  R Y+G PI C   ++     ED    +CW+ +T+                P  +N   R   T K   YYQW    L  QA++FY P  +W+   ++ G          G  ++L+ D++          I  C +   +  K+  +    + L Y                  +  + Y + ++L +INV+ QM+LM RF   +   FG+KV ID +   + +        FPR+T C   +    GE   ++  C+LPLN+  EKIYIFLWF+
Sbjct:    7 VYAFMQVSRSSVSHVKIDSP-VFRLHTNATVILLITFSIAVTTRQYVGNPIDCVHTRDIP---EDVLNTYCWIHSTYTVVDAFMKKQGSEVPFPGVHNSQGRGPLTIKHTKYYQWVAFTLFFQAILFYTPRWLWK---SWEG----------GKIHALIMDLD----------IGICSEAEKKQKKKLLLDYLWENLRYHN----------------WWAYRYYVCELLALINVIGQMFLMNRFFDGEFITFGLKV-IDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICILPLNVVNEKIYIFLWFW 280
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: shakB (gene:FBgn0085387 transcript:FBtr0309370)

HSP 1 Score: 88.5817 bits (218), Expect = 1.302e-18
Identity = 85/318 (26.73%), Postives = 136/318 (42.77%), Query Frame = 2 
Query:  302 VWKIAKLGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYA--------------PINNNLPLRMDKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGN----FPRVTFCE-VQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFY 1198
            V+   ++ R   SH++ D   V RL+   T  L   F   +  R Y+G PI C   ++     ED    +CW+ +T+                P  +N   R   T K   YYQW    L  QA++FY P  +W+   ++ G          G  ++L+ D++          I  C +   +  K+  +    + L Y                  +  + Y + ++L +INV+ QM+LM RF   +   FG+KV ID +   + +        FPR+T C   +    GE   ++  C+LPLN+  EKIYIFLWF+
Sbjct:    7 VYAFMQVSRSSVSHVKIDSP-VFRLHTNATVILLITFSIAVTTRQYVGNPIDCVHTRDIP---EDVLNTYCWIHSTYTVVDAFMKKQGSEVPFPGVHNSQGRGPLTIKHTKYYQWVAFTLFFQAILFYTPRWLWK---SWEG----------GKIHALIMDLD----------IGICSEAEKKQKKKLLLDYLWENLRYHN----------------WWAYRYYVCELLALINVIGQMFLMNRFFDGEFITFGLKV-IDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICILPLNVVNEKIYIFLWFW 280
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: shakB (gene:FBgn0085387 transcript:FBtr0342859)

HSP 1 Score: 88.5817 bits (218), Expect = 1.302e-18
Identity = 85/318 (26.73%), Postives = 136/318 (42.77%), Query Frame = 2 
Query:  302 VWKIAKLGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYA--------------PINNNLPLRMDKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGN----FPRVTFCE-VQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFY 1198
            V+   ++ R   SH++ D   V RL+   T  L   F   +  R Y+G PI C   ++     ED    +CW+ +T+                P  +N   R   T K   YYQW    L  QA++FY P  +W+   ++ G          G  ++L+ D++          I  C +   +  K+  +    + L Y                  +  + Y + ++L +INV+ QM+LM RF   +   FG+KV ID +   + +        FPR+T C   +    GE   ++  C+LPLN+  EKIYIFLWF+
Sbjct:    7 VYAFMQVSRSSVSHVKIDSP-VFRLHTNATVILLITFSIAVTTRQYVGNPIDCVHTRDIP---EDVLNTYCWIHSTYTVVDAFMKKQGSEVPFPGVHNSQGRGPLTIKHTKYYQWVAFTLFFQAILFYTPRWLWK---SWEG----------GKIHALIMDLD----------IGICSEAEKKQKKKLLLDYLWENLRYHN----------------WWAYRYYVCELLALINVIGQMFLMNRFFDGEFITFGLKV-IDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICILPLNVVNEKIYIFLWFW 280
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: zpg (gene:FBgn0024177 transcript:FBtr0076983)

HSP 1 Score: 87.4261 bits (215), Expect = 2.844e-18
Identity = 96/380 (25.26%), Postives = 161/380 (42.37%), Query Frame = 2 
Query:  335 SSHLRFDD----DWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWV------SNTFYAPINNNLP-LRMDKTSKL--------IGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGV--KVLIDLINGF--EWN--HSGNFPRVTFCEV-QTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWL-------LRMGYVKSRWKFI-RKYLKILNAMRETDNTATLKFTENNLRPD 1372
            S +L+F      D +  L+ ++T  L      +L  + Y G PIQC+  ++      DY   FCW+       N    P+ N     R D  SK+        I YYQW  +VL +++ +FY+P  +W+             I   G    L  D +   +                 CK      D  + + R   N FS     T H R+ F  Y   ++L +   +L   L+  F G    F+G     L+ L NG   +WN      FP+   CE+ +    G +NIY+  C+LPLN+  EKI+ FLW +++++ ++ +  F   L       +R+  +++R +F+ +K+L++        +   L    NN+ P+
Sbjct:    9 SKYLQFKSVHIYDAIFTLHSKVTVALLLACTFLLSSKQYFGDPIQCFGDKDM-----DYVHAFCWIYGAYVSDNVTVTPLRNGAAQCRPDAVSKVVPPENRNYITYYQWVVLVLLLESFVFYMPAFLWK-------------IWEGGRLKHLCDDFHKMAV-----------------CK------DKSRTHLRVLVNYFSSDYKET-HFRY-FVSYVFCEILNLSISILNFLLLDVFFG---GFWGRYRNALLSLYNGDYNQWNIITMAVFPKCAKCEMYKGGPSGSSNIYDYLCLLPLNILNEKIFAFLWIWFILVAMLISLKFLYRLATVLYPGMRLQLLRARARFMPKKHLQVALRNCSFGDWFVLMRVGNNISPE 342
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: zpg (gene:FBgn0024177 transcript:FBtr0330185)

HSP 1 Score: 87.4261 bits (215), Expect = 2.844e-18
Identity = 96/380 (25.26%), Postives = 161/380 (42.37%), Query Frame = 2 
Query:  335 SSHLRFDD----DWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWV------SNTFYAPINNNLP-LRMDKTSKL--------IGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGV--KVLIDLINGF--EWN--HSGNFPRVTFCEV-QTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWL-------LRMGYVKSRWKFI-RKYLKILNAMRETDNTATLKFTENNLRPD 1372
            S +L+F      D +  L+ ++T  L      +L  + Y G PIQC+  ++      DY   FCW+       N    P+ N     R D  SK+        I YYQW  +VL +++ +FY+P  +W+             I   G    L  D +   +                 CK      D  + + R   N FS     T H R+ F  Y   ++L +   +L   L+  F G    F+G     L+ L NG   +WN      FP+   CE+ +    G +NIY+  C+LPLN+  EKI+ FLW +++++ ++ +  F   L       +R+  +++R +F+ +K+L++        +   L    NN+ P+
Sbjct:    9 SKYLQFKSVHIYDAIFTLHSKVTVALLLACTFLLSSKQYFGDPIQCFGDKDM-----DYVHAFCWIYGAYVSDNVTVTPLRNGAAQCRPDAVSKVVPPENRNYITYYQWVVLVLLLESFVFYMPAFLWK-------------IWEGGRLKHLCDDFHKMAV-----------------CK------DKSRTHLRVLVNYFSSDYKET-HFRY-FVSYVFCEILNLSISILNFLLLDVFFG---GFWGRYRNALLSLYNGDYNQWNIITMAVFPKCAKCEMYKGGPSGSSNIYDYLCLLPLNILNEKIFAFLWIWFILVAMLISLKFLYRLATVLYPGMRLQLLRARARFMPKKHLQVALRNCSFGDWFVLMRVGNNISPE 342
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q03412|UNC7_CAEEL (Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN=unc-7 PE=1 SV=1)

HSP 1 Score: 276.559 bits (706), Expect = 6.789e-85
Identity = 145/380 (38.16%), Postives = 227/380 (59.74%), Query Frame = 2 
Query:  347 RFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRM-DKTSKLIGYYQWTPIVLAVQALMFYIPCLIWR-LLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYID-----TCIDR--NYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKIL---NAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWN 1450
            R DDD+VD+LNY  T  +   F  ++  + Y+G PIQCW P  F  A E Y+EN+CWV NT++ P+  ++P  +  + ++ IGYYQW P +LA++AL+FY+PC++WR LL  +SG N++ ++QMA D   +  +I ++ +  +AR++      T IDR  + R C  N           +   NC  RHC     G ++  LY  +KVLY  NVLLQ +L+   LG++   +G  +L DL++  EW  +G FPRVT C+ + + LG  + + +QCVL +NMF EKI++FLWF+++  GI+T  +   W+L M        F+RKYL++L    A    D+    KFT N LR DGVF++ +++ + G +++ +L + LW 
Sbjct:  136 RLDDDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDEVQLTNIDRQGHSRSCFSN----------LQLGANC-GRHC-----GCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQ 499
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O01393|UNC9_CAEEL (Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN=unc-9 PE=1 SV=1)

HSP 1 Score: 265.388 bits (677), Expect = 3.622e-82
Identity = 138/377 (36.60%), Postives = 222/377 (58.89%), Query Frame = 2 
Query:  329 VGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLR-MDKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIY 1456
            V S     DDD +D+LNY  T  +  +F  ++  + Y+G PIQCW P  F +  E Y+EN+CWV NT++ P+++ +P    ++ ++ IGYYQW P VLA++AL+FY+P ++WRLL   SG +V+ ++QMA D+  L  +  ++ ++ IA  ++  +   ++    N++    K LN            C  + G  + FLY  VK+LY +N++ Q++L+  FLG  S ++G++VL DL+NG EW  SG+FPRVT C+ + K LG  + + +QCVL +NMF EKI++FLWF+Y +L   T  S   W+        +  F+ KYL  +   +  D+ +  +F  + LR DGVF++ +V  + G +   +L   LWN Y
Sbjct:   12 VKSIQFHVDDDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLHDYIPHNYAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRL----KLLNLI---------ICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNY 375
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q22549|INX10_CAEEL (Innexin-10 OS=Caenorhabditis elegans OX=6239 GN=inx-10 PE=3 SV=1)

HSP 1 Score: 233.802 bits (595), Expect = 3.097e-68
Identity = 135/386 (34.97%), Postives = 212/386 (54.92%), Query Frame = 2 
Query:  311 IAKLGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLP-LRMD-KTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDS-NFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILN-AMRETDNTATLK---FTENNLRPDGVFIIYLVTINVGHIVAGDLTVELW 1447
            ++ L  VG S    D D+VDRL+   TC L      ++  + + GKP++C  P  F+ +WE Y+EN+CW S+T+Y P N  +  L+ D K  + I YYQW P  L ++A  F +P L+W+ L  +SG  +  I++++ D N++ PDI   NIK +  ++   + R +R  ++ QI        +    + F           F+  +Y   K  Y+ NV LQ+  M RFL TD   ++G+  L+DL+NG  W  SG FPRV+ C+   + +G    + +QCVL +N+F EKI+I LWF+Y+ L + T  SF  WLL   +     +FI ++L++ + A   +++ A  K   F  N L+ DGVF+I ++T+  G I   DL  ELW
Sbjct:    7 LSMLRYVGGSD---DRDFVDRLHSYFTCNLLIGLAVLVSFKQFGGKPVECLVPDIFSSSWEQYAENYCWASDTYYVPTNEPVAGLQSDEKRQRKISYYQWVPFFLLLEAACFRLPSLLWKYLAGHSGIKINEIVKLSSDPNNIKPDIKRANIKSLTVHLQGAL-RFHRRLQKKQIRPHRFLWLFNLPYSAF-----------FVTAMYLCTKFFYLANVCLQLMFMNRFLETDKYKWYGMGALVDLLNGTTWEQSGMFPRVSLCDFDVRVMGNMQEHTIQCVLVINIFNEKIFILLWFWYLALLVFTFGSFFYWLLVSLWRHLNVRFIIRHLEMSDIAFDSSEDGAQEKVNRFISNYLKSDGVFVIRMMTLQSGVIFGTDLVQELW 377
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q19746|INX3_CAEEL (Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx-3 PE=1 SV=2)

HSP 1 Score: 223.787 bits (569), Expect = 6.556e-66
Identity = 129/403 (32.01%), Postives = 199/403 (49.38%), Query Frame = 2 
Query:  356 DDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRM-DKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCH---TNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRHKSWQDNDNVRYLDMDCRRSVVPGVALHHYN 1552
            DD VDRL+Y  T  L   F  ++  + Y+G  IQCW P EF   WE Y+E++C++ NTF+ P  + +P  + D+    IGYYQW PIVLA+QA MFY+P  IW  L    G +   +I  A    S   +  +K +  +  +I                   G  L+ R K N + R  C+      G     LY  +K++Y+ NV +Q  ++ +FLG ++  +G     DL  G EW  SG FPRVT C+   +KL   + Y +QCVL +NMF EKIY+F+WF++V + I T  +    + R+ +  SR  +IR  L       + +      F  N L+ DGV ++  +  + G +V  ++  EL+  +      + D   +      +S  PG+   H+ 
Sbjct:   21 DDAVDRLSYVTTATLLAFFSIMVSCKQYVGSAIQCWMPMEFKGGWEQYAEDYCFIQNTFFIPERSEIPGDVEDRQKAEIGYYQWVPIVLAIQAFMFYLPSWIWSSLYKQCGLDFPSVISEAEALRSQDSETRTKGVNKLVDFI-------------------GDILDTRSK-NEYGRFYCYRFGKGLGSMTSMLYICIKLMYLANVFVQFIILNKFLGNETFLWGFHTFADLYAGREWQDSGVFPRVTLCDFSVRKLANVHRYTVQCVLMINMFNEKIYLFIWFWFVFVLITTFINTLCTIYRLSFDSSRHNYIRSLLSGPVNNFKDEKAMIASFANNGLKQDGVLLMRFIDDHAGAMVTKEICEELFKKHGENLQHNRD---FHHGHSTKSTSPGLEEGHHE 400
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q23157|INX11_CAEEL (Innexin-11 OS=Caenorhabditis elegans OX=6239 GN=inx-11 PE=3 SV=1)

HSP 1 Score: 223.402 bits (568), Expect = 3.141e-65
Identity = 122/393 (31.04%), Postives = 210/393 (53.44%), Query Frame = 2 
Query:  320 LGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRMDKT----SKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSN-FFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYV-KSRWKFIRKYLKI--------LNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIY 1456
            LG       R DDDW DRLNY +T  +   F  ++  + + G+PI+C  P +F  +WE Y+EN+CW  +T++     ++ L   +      + + YYQW P  L +QA  F  P  +W+   N+SG  +  +++ A D+ ++  ++  KNI  + R++ + +        R Q +++ K++   K     +          F+ ++Y   KVLY +NV  Q+YLM  FLGT+ + ++G  V+ D++ G  W  SG FPR   C+ + +++     Y++QCVL +N+F EKI++ LWF+YVIL + +T S   W + + +   S+W F++++L +         N+ RE  + +  KF    L  DGVF++ +V+ + G I A DL   L+  Y
Sbjct:    8 LGMAKYLSPREDDDWSDRLNYLMTPNILLAFSVLISFKQFGGRPIECMFPNKFPGSWEQYAENYCWSQDTYFVEPTQDVSLLKKEERYTPDRQLSYYQWVPFFLLLQAAFFRAPSYLWKYFSNHSGIRIHEVVEKAKDSANVEEEVREKNILILKRHLSSAL--------RFQANMERKKVQVHKTVTFLNFQYS----SGFISWIYLFTKVLYFLNVFAQLYLMNYFLGTNRHHWYGFGVVQDIVQGEPWERSGYFPRAAVCDFEVRQVANIQRYSVQCVLVINIFNEKIFVLLWFWYVILLLSSTVSLVQWFIVLVFPCFSKW-FVKQHLALSTLQNFNQRNSRREDSDVS--KFVTQYLHKDGVFVLRMVSSHAGIIFATDLVQALYEAY 385
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A1I8GCN3 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 493.812 bits (1270), Expect = 2.748e-168
Identity = 233/417 (55.88%), Postives = 305/417 (73.14%), Query Frame = 2 
Query:  287 MDATLVWKIAKLGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPI-NNNLPLRMDKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRHKSWQDNDNVRYLDMDCRRSVVPGV 1534
            MDAT +WK++KLGR+GSS LRFDDD+ DRLNYQ T  + FLFIG++G+R Y+GKPIQCW PQEF + WE+Y+EN+CWV+NT+YA +   +LP    +  ++I YYQW PIVLAVQALMFY+PCLIWRL MNYSGFNVR+I+QMA D N ++P+  +KNI+F+ARY++ CI R  R+ +R    V  +  +   KC+C    CC   +G FL  LY  +KVLY++NV  Q+Y+M++F+GT   FFG +VL DL NG +W  S NFPRVTFC++Q KKLG N  Y LQCVLPLNMFLEKIY+FLWF++V++ I+T  SF +W  RM + + R  F+RKYLKI+N +++TD T + KF EN LR DGVFI  L+ +N G IVAGDL  ELW+IYRHK  Q+ D+ +    D R    PG+
Sbjct:    1 MDATFMWKLSKLGRIGSSKLRFDDDFADRLNYQFTGVILFLFIGLIGIRQYVGKPIQCWIPQEFTRGWEEYAENYCWVANTYYASVPEEHLPAEHLRRKRMITYYQWAPIVLAVQALMFYLPCLIWRLFMNYSGFNVRKILQMATDANVVIPEALNKNIRFMARYMEGCIYRQ-REYRR---GVGVRVKHCLAKCSCL---CCGKRYGNFLVVLYFFIKVLYLLNVFGQLYIMEKFVGTTYTFFGFQVLRDLFNGIQWYQSSNFPRVTFCDLQAKKLGVNYHYTLQCVLPLNMFLEKIYVFLWFWHVLVSIVTLGSFVNWFFRMAFARRRLIFVRKYLKIMNVLKDTDKTTSRKFVENYLRIDGVFIFRLIAMNCGDIVAGDLACELWSIYRHKRLQELDDTKLETTDHRHVGFPGL 410
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A267EEW5 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 477.633 bits (1228), Expect = 5.169e-162
Identity = 227/417 (54.44%), Postives = 308/417 (73.86%), Query Frame = 2 
Query:  287 MDATLVWKIAKLGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPIN-NNLPLRMDKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRHKSWQDNDNVRYLDMDCRRSVVPGV 1534
            MDAT +WK++KLGR+GSS LRFDDD+ DRLNYQ T  + FLFIG++G+R Y+GKPIQCW PQEF + WE+Y+EN+CWV+NT+YA +  ++LP +  +   +I YYQW PIVLAVQALMFY+PCLIWRL MNYSGFN+R+I+QMA D N ++P+  +KN++F+ARY++ CI R  R+ +R      G  +  +   +  S  CC   +G FL  LY  +KVLY++NV  Q+Y+M++F+GT   FFG +VL+D+++G +W  S NFPRVTFC++Q KK G+N  Y LQCVLPLNMFLEKIY+FLWF++V++ I+T  SF +W  RM + + R  FIRKYLKI+N +++TD T + KF EN LR DGVFI  L+ +N G IVAGDL  ELW+IYRHK  Q+ D+ + L+ D R +   G+
Sbjct:    1 MDATFMWKLSKLGRIGSSKLRFDDDFADRLNYQFTGVILFLFIGLIGIRQYVGKPIQCWIPQEFTRGWEEYAENYCWVANTYYASVQADHLPPQHIRNELMITYYQWAPIVLAVQALMFYLPCLIWRLFMNYSGFNLRKILQMATDANVVIPEALNKNVRFMARYMEGCIYRQ-REYRR------GVGVRLKHCLSKCSCLCCGKRYGNFLVVLYFFIKVLYLLNVFGQLYIMEKFIGTTYTFFGFRVLLDIVHGIKWYQSSNFPRVTFCDLQAKKEGQNYHYTLQCVLPLNMFLEKIYVFLWFWHVLVSIVTLTSFVNWFFRMAFARRRLNFIRKYLKIMNVLKDTDKTTSRKFVENYLRVDGVFIFRLIAMNCGDIVAGDLACELWSIYRHKRLQELDDTK-LEPDHRHTAFAGM 409
[Close]
BLAST of Innexin vs. TrEMBL
Match: Q2L6N1 (Innexin OS=Dugesia japonica OX=6161 GN=inx3 PE=2 SV=1)

HSP 1 Score: 479.174 bits (1232), Expect = 1.002e-161
Identity = 232/453 (51.21%), Postives = 329/453 (72.63%), Query Frame = 2 
Query:  287 MDATLVWKIAKLGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRMDKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTN-SLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQ--ISVDGKQLNYRK-----KCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRHKSWQDNDNVRYLDMDCRRSVVPGVALHHYNTSRLDSVNTNNHEKSN-NHDDIV 1618
            MDAT  W+++KLGR+GS+ LRFDDD+VDRLNYQ T  L F+FIG++G+R Y+GKPIQCW PQEF + WE+Y+EN+CWVSNT++A I N +P +  +  ++IGYYQW PI+L +Q+L+FYIPCLIWR +   SGFNVRRI+Q+A D N SL+P+   K+I FIAR++DTC+ R +R C  ++  +  +GK+  + +     +C C    C     G FL  LY  +K LY+IN++ Q+YLM++F+GT   F+G++VL DL+ G EW+HSGNFPRVTFC+++ KKLG+N++Y+LQCVLP+NMFLEKIYIFLWF++VI+GI T  S  SW+ R+G   +R K IR YL+++N + +TD   + KF E+ LR DG F+I L+ IN+G +VAGDL  E+W IYRHK  Q+ + +++  ++   S +P + L+  NTS L+  + N    +N NHD+IV
Sbjct:   39 MDATFFWRLSKLGRIGSNKLRFDDDFVDRLNYQFTGLLLFMFIGLIGIRQYVGKPIQCWIPQEFTRGWEEYTENYCWVSNTYFASIQNRMPSKDTRNEQMIGYYQWAPILLGLQSLLFYIPCLIWRNVSPQSGFNVRRILQVASDANCSLIPEQLQKSISFIARHMDTCLYR-HRICYEHKHFMRSNGKRSKFSRCLAKLRCIC----CLGKLQGNFLTVLYISIKFLYLINIIGQLYLMEKFIGTKYTFYGIRVLWDLMRGHEWHHSGNFPRVTFCDLEAKKLGKNHLYSLQCVLPMNMFLEKIYIFLWFWHVIVGIATLCSLFSWIRRIGSPVNRIKMIRNYLRLMNILHDTDKGPSRKFAESYLRSDGCFLIQLIAINIGDLVAGDLICEMWQIYRHKRIQEFEELKFTSLNV-ESRLPSLMLN--NTSNLNDYDKNGASNNNGNHDEIV 483
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A1I8GJJ5 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 478.404 bits (1230), Expect = 1.431e-160
Identity = 225/415 (54.22%), Postives = 299/415 (72.05%), Query Frame = 2 
Query:  287 MDATLVWKIAKLGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPIN-NNLPLRMDKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRHKSWQDNDNVRYLDMDCRRSVVP 1528
            MDAT +WK++KLGR+GSS  R DDD+ DRLNYQ +  + FLFIG++G+R Y+GKPIQCW PQEF + WE+Y+EN+CWV+NT+YA +  ++LP    ++   I YYQW PIVLAVQALMFYIPCLIWRL MNYSGFNVRR++QMA D N ++P+  +KN++F+ARY++ CI R  R+ KR      G  +  R+  +  S  CC   HG FL  LY  VK+LY++N   Q+YLM++F+GT   FFG +VL+D++ G  W  S NFPRVTFC++Q +K+G N  Y LQCVLPLNMFLEKIY+FLWF+  ++ +IT +SF SW  RM + + R  F+RKYLKI+NA+++TD   + KF EN LR DGVFI+ LV+ N G IVAGDL  ELW+IYRHK  Q+ ++ +     C    +P
Sbjct:   91 MDATFMWKLSKLGRIGSSRQRVDDDFADRLNYQFSGVILFLFIGLIGIRQYVGKPIQCWIPQEFTRGWEEYAENYCWVANTYYASLEADHLPEEQSRSRLTITYYQWAPIVLAVQALMFYIPCLIWRLFMNYSGFNVRRLLQMAADANVVIPEALNKNVRFMARYMEGCIYRQ-REYKR------GLGVRVRRCLSACSCICCGKRHGNFLVVLYFFVKLLYLLNAFGQLYLMEKFVGTTHTFFGFRVLLDILQGVHWYRSSNFPRVTFCDLQARKIGVNYRYTLQCVLPLNMFLEKIYVFLWFWVALVSVITMSSFVSWFCRMAFARRRTGFVRKYLKIMNALKDTDRLTSRKFVENYLRVDGVFILRLVSANCGDIVAGDLACELWSIYRHKRLQELEDTKLDAAACCHHDLP 498

HSP 2 Score: 75.0998 bits (183), Expect = 1.661e-10
Identity = 33/80 (41.25%), Postives = 54/80 (67.50%), Query Frame = 2 
Query: 1148 LPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFII 1387
            LP+N F+EK+Y+FLWF+Y+ILG++T  S   W+LR+     R  +I++YL+ +  +  T++    +F  N+L PDG FI+
Sbjct:    7 LPINHFVEKVYVFLWFWYIILGVLTLLSTIIWMLRILIPGGRVAYIKQYLRAMKLISNTEDRDCKRFVANSLGPDGGFIL 86
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A1I8GHL0 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 479.174 bits (1232), Expect = 3.583e-155
Identity = 227/417 (54.44%), Postives = 308/417 (73.86%), Query Frame = 2 
Query:  287 MDATLVWKIAKLGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPIN-NNLPLRMDKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRHKSWQDNDNVRYLDMDCRRSVVPGV 1534
            MDAT +WK++KLGR+GSS LRFDDD+ DRLNYQ T  + FLFIG++G+R Y+GKPIQCW PQEF + WE+Y+EN+CWV+NT+YA +  ++LP +  +   +I YYQW PIVLAVQALMFY+PCLIWRL MNYSGFN+R+I+QMA D N ++P+  +KN++F+ARY++ CI R  R+ +R      G  +  +   +  S  CC   +G FL  LY  +KVLY++NV  Q+Y+M++F+GT   FFG +VL+D+++G +W  S NFPRVTFC++Q KK G+N  Y LQCVLPLNMFLEKIY+FLWF++V++ I+T  SF +W  RM + + R  FIRKYLKI+N +++TD T + KF EN LR DGVFI  L+ +N G IVAGDL  ELW+IYRHK  Q+ D+ + L+ D R +   G+
Sbjct:  567 MDATFMWKLSKLGRIGSSKLRFDDDFADRLNYQFTGVILFLFIGLIGIRQYVGKPIQCWIPQEFTRGWEEYAENYCWVANTYYASVQADHLPPQHIRNELMITYYQWAPIVLAVQALMFYLPCLIWRLFMNYSGFNLRKILQMATDANVVIPEALNKNVRFMARYMEGCIYRQ-REYRR------GVGVRLKHCLSKCSCLCCGKRYGNFLVVLYFFIKVLYLLNVFGQLYIMEKFIGTTYTFFGFRVLLDIVHGIKWYQSSNFPRVTFCDLQAKKEGQNYHYTLQCVLPLNMFLEKIYVFLWFWHVLVSIVTLTSFVNWFFRMAFARRRLNFIRKYLKIMNVLKDTDKTTSRKFVENYLRVDGVFIFRLIAMNCGDIVAGDLACELWSIYRHKRLQELDDTK-LEPDHRHTAFAGM 975

HSP 2 Score: 157.918 bits (398), Expect = 7.253e-37
Identity = 84/244 (34.43%), Postives = 140/244 (57.38%), Query Frame = 2 
Query:  446 KPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRMDKTSKL--IGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRI-IQMAGDTNSLVPD--INSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLG---ENNIYNLQCVLP 1153
            KPIQCW PQEF+KAWED++EN+CWVSNT++     ++P++ ++  ++  I YYQW  IVLA QA++ +IP L+WR+         RR+ + +     + +PD  +  K ++ +   ++   + + R               Y +  N   +  C  +    L  L+ IV++L++ N + Q+YLM++FLGT+  FFG +VL  L  G EW  +G+FPRVT+C +  +K+G   ++++   Q V P
Sbjct:    1 KPIQCWVPQEFSKAWEDFAENYCWVSNTYFLMPEQDIPVKTEQLKQMTFITYYQWVAIVLAGQAIITWIPHLLWRV-------GARRLPVLIKNARGASIPDTDLRRKAVQCLVAALEEQAEASRR---------------YSRMKNVVEKFLCCLSPSMRLTMLFLIVRILFIGNSIGQIYLMRQFLGTNDTFFGYEVLKSLTLGREWRETGHFPRVTYCHLVVRKVGVKSQSDVTPQQPVRP 222

HSP 3 Score: 92.4337 bits (228), Expect = 1.200e-15
Identity = 44/118 (37.29%), Postives = 72/118 (61.02%), Query Frame = 2 
Query: 1109 KLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRH 1462
            ++  +  ++LQCVLP+N F+EK+Y+FLWF+++ILG++T AS   W+ +      R  FI++YLK +  +  T+     +F   NL  DGVFI+ +V+     ++A D+   LW  YR 
Sbjct:  383 RIRNSGSFDLQCVLPINHFVEKVYVFLWFWFIILGVLTFASTLLWVFKTLIPYRRVAFIKQYLKAMRILSNTEERDCNRFVNINLGADGVFILQVVSNLASDLIALDVASTLWKNYRQ 500
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000048374.1 (SMESG000048374.1)

HSP 1 Score: 917.531 bits (2370), Expect = 0.000e+0
Identity = 443/444 (99.77%), Postives = 444/444 (100.00%), Query Frame = 2 
Query:  287 MDATLVWKIAKLGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRMDKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRHKSWQDNDNVRYLDMDCRRSVVPGVALHHYNTSRLDSVNTNNHEKSNNHDDIV 1618
            MDATLVWKIAKLGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRMDKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVL+DLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRHKSWQDNDNVRYLDMDCRRSVVPGVALHHYNTSRLDSVNTNNHEKSNNHDDIV
Sbjct:    1 MDATLVWKIAKLGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRMDKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLVDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRHKSWQDNDNVRYLDMDCRRSVVPGVALHHYNTSRLDSVNTNNHEKSNNHDDIV 444
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000060499.1 (SMESG000060499.1)

HSP 1 Score: 462.225 bits (1188), Expect = 1.802e-158
Identity = 224/443 (50.56%), Postives = 321/443 (72.46%), Query Frame = 2 
Query:  296 TLVWKIAKLGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRMDKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTN-SLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQ--ISVDGKQLNYRK-----KCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRHKSWQDNDNVRYLDMDCRRSVVPGVALHHYNTSRLDSVNTNNHEKSN 1600
            T  W+++KLGR+GS+ LRFDDD+VDRLNYQ T  L F+FIG++G+R Y+GKPIQCW PQEF + WE+Y+EN+CWVSNT++A I N +P +  +  ++IGYYQW PI+L +Q+L+FYIPCLIWR +   SGFNVRRI+Q+A D N SL+P+   K+I FIAR++DTC+ R +R C  ++  +  +GK+    +     +C C    C     G FL  LY  +K+LY+IN++ Q+YLM++F+GT   F+G++VL DL+ G EW++SGNFPRVTFC+++ KKLG+N++Y+LQCVLP+NMFLEKIYIFLWF++VI+GI T  S  SW+ R+G   +R K IR YL+++N + +TD   + KF E+ LR DG F+I L+ IN+G +VAGDL  E+W IYRHK  Q+ + +++  ++   S +P + L+  NTS     N N+++KS 
Sbjct:   42 TFFWRLSKLGRIGSNKLRFDDDFVDRLNYQFTGLLLFMFIGLIGIRQYVGKPIQCWIPQEFTRGWEEYTENYCWVSNTYFASIQNRMPSKDARKEQMIGYYQWAPILLGLQSLLFYIPCLIWRNVSPQSGFNVRRILQVASDANCSLIPEQLQKSISFIARHMDTCLYR-HRICYEHKHFMRTNGKRSTISRCLAKLRCIC----CLGKLQGNFLTVLYISIKILYLINIIGQLYLMEKFIGTKYAFYGIRVLWDLMRGHEWHYSGNFPRVTFCDLEAKKLGKNHLYSLQCVLPMNMFLEKIYIFLWFWHVIVGIATLFSLFSWIKRIGSPVNRIKMIRNYLRLMNILHDTDKGPSRKFAESYLRSDGCFLIQLIAINIGDLVAGDLICEMWQIYRHKRIQEFEELKFTSLNV-ESRLPSLMLN--NTS-----NLNDYDKSG 471
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000045304.1 (SMESG000045304.1)

HSP 1 Score: 427.172 bits (1097), Expect = 1.019e-144
Identity = 210/440 (47.73%), Postives = 297/440 (67.50%), Query Frame = 2 
Query:  287 MDATLVWKIAKLGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRMDKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAG-DTNSLVPDINSK---------NIKFIARYIDTCIDRNY----------RDCKRNQISVDGKQLNYRKKCNCFSR---------HCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRHKSWQDNDNVRYLDMDCRRS 1519
            MDAT VWK+ KLGR+GS+ LR+DDD+VDRLNYQ T  + FLFIG++ +R YIGKPIQCW PQEF + WE+Y+EN+CW++NT++A I    P ++++  ++IGYYQW PI +A+QALMFY+PCLIWR L + SGFNVRR+IQMA  D N ++ + N +           +F+ RYI  CI R              CK+     + + L +    +C SR          CC   +G +L  LY  VK LY+IN+++Q+Y+M+ F+G   +F+G+++LIDLI G  W +SG+FPRVTFC+++ KKLG+NN+Y LQCVLP+NMFLEKI+IFLWF++V+LGI+   S  SW  ++  +K R KFIRK L+I   +++TD +A+ +F    L+PD VFI+ L+  N+G I+  DLT ELW IYRHK   + D+++   +  R S
Sbjct:    1 MDATFVWKLGKLGRLGSNRLRYDDDFVDRLNYQFTGVILFLFIGLVSIRQYIGKPIQCWIPQEFTRGWEEYAENYCWIANTYFATIRGQFPHKINRKERMIGYYQWAPIFMALQALMFYLPCLIWRGLNHKSGFNVRRLIQMASSDPNIILSNFNCEYKPGPSSNAACRFMGRYISNCILRRQVRSRGLLKSGHSCKKG----ENESLLFPISNSCCSRCCANHGCFESCCGRRNGNYLISLYITVKFLYLINIIIQLYIMELFIGASYSFYGLRLLIDLIKGKHWYNSGHFPRVTFCDLEAKKLGKNNLYTLQCVLPMNMFLEKIFIFLWFWHVLLGIVNFLSILSWSRQILSLKRRIKFIRKQLRISGVLKDTDLSASRQFVLQYLKPDVVFILKLIGSNIGEIIVTDLTTELWYIYRHKRLNECDDIKNTTIMMRSS 436
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000059204.1 (SMESG000059204.1)

HSP 1 Score: 419.853 bits (1078), Expect = 1.853e-142
Identity = 213/455 (46.81%), Postives = 296/455 (65.05%), Query Frame = 2 
Query:  287 MDATLVWKIAKLGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRMDKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSK--------NIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRHCCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRHKSWQDNDNVRYLD---MDCRRSVVPGVALHHYNTSRLDSVNTNNHEKSNNHDDIV 1618
            MDAT VWK+AKLGR+GSSHLR+DDD++DRLNYQ+T  L FLFIG++G+R Y+GKPIQCW+PQEF + WE+Y+EN+CWVSNT+Y+ +   LP + D+   +IGYYQW  I L VQAL+FY+PC+IWR L N S FN+RRIIQM+     ++  ++ K        +IKFIA+Y+D+CI R +    + +  ++    N +      S  CC    G  L  LY  +K+LY++N + Q+YLM+ F+GT +  +GV VLIDL+ G  WN SG+FPRVTFC+ Q KKLG+N+IY LQCVLP+NM LEKI+I LWF+ V+L II   SF +W  R+   + R +FIRK+L I+ A+  +D   +  F E+ L  D VFII L++ N    VA  L  ELW IYRH+   + +++++        ++S + GV   + N     +   NN       DDIV
Sbjct:    1 MDATFVWKLAKLGRLGSSHLRYDDDFIDRLNYQVTGILLFLFIGIIGIRQYVGKPIQCWSPQEFTRGWEEYAENYCWVSNTYYSSVTVRLPPKTDRRVLMIGYYQWAWIFLGVQALLFYLPCIIWRGLYNQSRFNIRRIIQMSASATDIIMPLSEKSGNSSSNTSIKFIAKYLDSCIRRRHLGRCKPEKKLNN---NIKPGHQVSSPWCCSHKSGNCLSILYLFIKLLYILNAISQVYLMEAFIGTKNILYGVIVLIDLLKGRHWNESGHFPRVTFCDFQAKKLGKNHIYTLQCVLPINMILEKIFIILWFWIVLLAIINIFSFINWTGRLLQSRFRVQFIRKHLHIMGALVSSDRPMSRHFVEHYLGADVVFIIRLISTNSCEFVASQLANELWMIYRHRRHAELEDMKFGHGSLSPSQKSKLSGVCFGNSNRCVPLTSGANN-------DDIV 445
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000048827.1 (SMESG000048827.1)

HSP 1 Score: 410.994 bits (1055), Expect = 1.005e-138
Identity = 197/400 (49.25%), Postives = 275/400 (68.75%), Query Frame = 2 
Query:  287 MDATLVWKIAKLGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRMDKTSKLIGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYRDCKRNQI----SVDGKQLNYRKKCNCFSRHCCHTN--HGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLIDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTATLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRHKS 1468
            +D   +W   KLGR GS HLR DDD  DRLNY+++  L F FI ++GLR Y+GKPIQCW PQEF + WE+YSEN+CW+++T++AP++  LP ++D+  +LIGYYQW PI+LA+Q  +FY+P LIW+    YS +N+ ++I +  DT   +    SK I F ARYID CI R  +  KR+      +   K  +  K  NC      H    +G FL  LY  VK+LY+ N++ Q+YLM++  G+  +FFG+++LIDLI G EW  SGNFPRVTFC+++TKKLG+N +Y +QCVLP+N+FLEKIY+FLWF++VIL IIT+ S   W +R+G +K R K IRKYL+  NA+ +TD + T KF    L+ DGVF+++++ ++ G IVA  +  ELWNIYRHK 
Sbjct:   35 LDCNFLWNFNKLGRWGSRHLRSDDDMADRLNYKVSSLLMFGFISLIGLRQYVGKPIQCWIPQEFTRGWEEYSENYCWIASTYFAPVSEKLPSKVDRQKRLIGYYQWAPIILALQGFLFYMPYLIWKSCSFYSIYNLPKLISVTEDT---LDTEASKTIVFAARYIDLCIQRQ-KKLKRSSTQCIKTACYKSFSCTKPKNCVVSLHFHIGRMYGNFLVSLYYFVKILYIFNLIGQLYLMEKIFGSSKSFFGMRILIDLIRGMEWQRSGNFPRVTFCDIETKKLGKNYLYTVQCVLPMNIFLEKIYLFLWFWHVILVIITSTSLFWWFVRIGTLKRRLKTIRKYLQFQNAIGDTDKSTTRKFVTKYLQIDGVFLVHMLALSDGEIVAAGMVGELWNIYRHKG 430
The following BLAST results are available for this feature:
BLAST of Innexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
inx-11.705e-9438.13Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-11.705e-9438.13Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-14.155e-9338.86Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
unc-73.258e-8737.80Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q0... [more]
unc-76.589e-8738.36Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q0... [more]
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BLAST of Innexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
shakB1.302e-1826.73gene:FBgn0085387 transcript:FBtr0309369[more]
shakB1.302e-1826.73gene:FBgn0085387 transcript:FBtr0309370[more]
shakB1.302e-1826.73gene:FBgn0085387 transcript:FBtr0342859[more]
zpg2.844e-1825.26gene:FBgn0024177 transcript:FBtr0076983[more]
zpg2.844e-1825.26gene:FBgn0024177 transcript:FBtr0330185[more]
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BLAST of Innexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q03412|UNC7_CAEEL6.789e-8538.16Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|O01393|UNC9_CAEEL3.622e-8236.60Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q22549|INX10_CAEEL3.097e-6834.97Innexin-10 OS=Caenorhabditis elegans OX=6239 GN=in... [more]
sp|Q19746|INX3_CAEEL6.556e-6632.01Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx... [more]
sp|Q23157|INX11_CAEEL3.141e-6531.04Innexin-11 OS=Caenorhabditis elegans OX=6239 GN=in... [more]
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BLAST of Innexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8GCN32.748e-16855.88Innexin OS=Macrostomum lignano OX=282301 GN=inx PE... [more]
A0A267EEW55.169e-16254.44Innexin OS=Macrostomum lignano OX=282301 GN=inx PE... [more]
Q2L6N11.002e-16151.21Innexin OS=Dugesia japonica OX=6161 GN=inx3 PE=2 S... [more]
A0A1I8GJJ51.431e-16054.22Innexin OS=Macrostomum lignano OX=282301 GN=inx PE... [more]
A0A1I8GHL03.583e-15554.44Innexin OS=Macrostomum lignano OX=282301 GN=inx PE... [more]
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BLAST of Innexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000048374.10.000e+099.77SMESG000048374.1[more]
SMESG000060499.11.802e-15850.56SMESG000060499.1[more]
SMESG000045304.11.019e-14447.73SMESG000045304.1[more]
SMESG000059204.11.853e-14246.81SMESG000059204.1[more]
SMESG000048827.11.005e-13849.25SMESG000048827.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010455 ID=SMED30010455|Name=Innexin|organism=Schmidtea mediterranea sexual|type=transcript|length=1707bp
CGATTTACGGTTGGCCAGTGGAATCTTCCAATTAAAGTCTCTTGGAGTCA
ATATATTGTCCCTCTGCTGATAGAATTTATCAAATACTGATCAATTTAAA
CAAAAAAAAATTATTTGAGGACTTTTATCAGTTGAAAAATTTCAATGCCT
ATGATCTGATTGTCAAGCTCAAATGATTTTACCACGGGAATATTCAAGGG
CCCTTTGATAACCACCAACACTGATTAAGATCCTGTGAAACTATTGAAAT
CGGACTTAACCACATTCTGATTTCTAACCAAAACCAATGGATGCAACCTT
GGTTTGGAAAATTGCCAAGTTGGGTAGAGTTGGTTCCTCACATTTGCGTT
TTGATGATGACTGGGTTGACAGACTCAATTATCAAATCACATGCTTTCTT
CACTTTCTGTTTATTGGGGTTCTTGGCTTACGATCTTACATTGGTAAACC
GATTCAATGTTGGGCTCCACAAGAATTCAACAAAGCATGGGAAGACTATT
CCGAAAACTTCTGTTGGGTTTCCAACACATTTTATGCACCCATTAATAAT
AATTTACCTCTTCGAATGGATAAGACATCGAAACTGATTGGTTATTATCA
ATGGACTCCGATCGTTTTAGCTGTTCAGGCTTTGATGTTTTACATTCCAT
GCCTAATTTGGAGGTTGCTGATGAACTATTCTGGGTTTAACGTTCGAAGA
ATCATTCAAATGGCCGGAGATACAAACTCATTGGTTCCAGATATCAATTC
GAAAAACATCAAATTCATTGCGAGATATATCGACACTTGCATAGATAGAA
ACTACCGAGATTGTAAAAGAAATCAGATTTCTGTCGATGGAAAGCAACTG
AACTACAGAAAGAAATGCAACTGCTTCTCTCGACATTGTTGTCACACAAA
TCACGGACGATTTTTATTCTTTCTTTACGGAATTGTAAAGGTTCTTTATG
TGATTAATGTGTTGTTGCAAATGTATTTAATGAAACGATTTCTTGGAACA
GATTCAAACTTTTTCGGAGTTAAAGTTTTGATTGATCTCATCAATGGATT
TGAATGGAACCATTCCGGTAATTTTCCTCGAGTCACTTTTTGCGAGGTTC
AGACGAAGAAGCTAGGAGAAAATAACATATATAACCTTCAATGTGTGTTG
CCCTTAAACATGTTTTTGGAAAAAATTTATATATTTCTCTGGTTTTACTA
CGTGATCTTAGGAATTATAACCACTGCGAGTTTTTGCAGTTGGCTTTTAC
GTATGGGATATGTTAAATCTCGTTGGAAATTTATTCGAAAGTACCTTAAA
ATCTTAAATGCAATGCGAGAAACCGATAATACGGCTACTTTGAAATTCAC
GGAAAACAATTTACGTCCCGATGGCGTGTTTATCATTTATTTGGTGACGA
TTAATGTCGGTCACATTGTGGCTGGGGATCTGACGGTGGAACTGTGGAAC
ATTTATCGGCACAAAAGTTGGCAAGATAATGACAATGTTCGGTATCTTGA
TATGGACTGTCGACGTTCTGTAGTTCCAGGAGTTGCTCTTCACCATTACA
ATACGTCTAGATTAGACTCTGTCAACACAAACAATCATGAGAAATCTAAT
AATCATGATGATATTGTATGAGTTTGAATGTGTACAACTTGTACAATCTG
TACAATTTTAATGAGTATCTCTTTTTTCTATCACTGCTAAATATCAAAAG
ATTTCAA
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protein sequence of SMED30010455-orf-1

>SMED30010455-orf-1 ID=SMED30010455-orf-1|Name=SMED30010455-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=445bp
MDATLVWKIAKLGRVGSSHLRFDDDWVDRLNYQITCFLHFLFIGVLGLRS
YIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRMDKTSKL
IGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLV
PDINSKNIKFIARYIDTCIDRNYRDCKRNQISVDGKQLNYRKKCNCFSRH
CCHTNHGRFLFFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLID
LINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIF
LWFYYVILGIITTASFCSWLLRMGYVKSRWKFIRKYLKILNAMRETDNTA
TLKFTENNLRPDGVFIIYLVTINVGHIVAGDLTVELWNIYRHKSWQDNDN
VRYLDMDCRRSVVPGVALHHYNTSRLDSVNTNNHEKSNNHDDIV*
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Aliases
The feature 'Innexin' has the following synonyms
Synonym
Dj-inx3
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000025nervous system
PLANA:0000406oral opening
PLANA:0000418head
PLANA:0002056medial muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR000990Innexin
Vocabulary: cellular component
TermDefinition
GO:0005921gap junction
GO:0005886plasma membrane
GO:0016020membrane
GO:0016021integral component of membrane
GO:0030054cell junction
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0006811ion transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000990InnexinPRINTSPR01262INNEXINcoord: 214..228
score: 44.0
coord: 286..302
score: 63.06
coord: 103..125
score: 56.0
coord: 47..58
score: 42.0
coord: 75..84
score: 40.0
coord: 262..271
score: 58.0
IPR000990InnexinPFAMPF00876Innexincoord: 24..390
e-value: 2.8E-116
score: 388.6
IPR000990InnexinPANTHERPTHR11893INNEXINcoord: 21..400
IPR000990InnexinPROSITEPS51013PANNEXINcoord: 19..396
score: 33.516
NoneNo IPR availableTMHMMTMhelixcoord: 299..321
NoneNo IPR availableTMHMMTMhelixcoord: 106..128
NoneNo IPR availableTMHMMTMhelixcoord: 30..52
NoneNo IPR availableTMHMMTMhelixcoord: 209..231