GCR317

Overview
NameGCR317
Smed IDSMED30010426
Length (bp)1340
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of GCR317 (SMED30010426) t-SNE clustered cells

Violin plots show distribution of expression levels for GCR317 (SMED30010426) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of GCR317 (SMED30010426) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for GCR317 (SMED30010426) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30010426

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30010426SMESG000074480.1 dd_Smed_v4_14520_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30010426SMESG000074480.1 dd_Smed_v4_14520_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30010426SMESG000074480.1 dd_Smed_v4_14520_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30010426SMESG000074480.1 dd_Smed_v4_14520_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30010426SMESG000074480.1 dd_Smed_v6_14520_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
enteric muscle cellSMED30010426SMESG000074480.1 dd_Smed_v4_14520_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of GCR317 vs. Ensembl Human
Match: GALR2 (galanin receptor 2 [Source:HGNC Symbol;Acc:HGNC:4133])

HSP 1 Score: 146.362 bits (368), Expect = 5.898e-39
Identity = 96/322 (29.81%), Postives = 160/322 (49.69%), Query Frame = 3 
Query:  201 SSNSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMD--GYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNN-----QQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFK 1145
            +S +   G     ++IVP LF +IF+VG +GN LV+AV++R G   ++TN+ I +L  ADL FI+ C+P   +IY   GW++ + LC    +L +LT++ S +TL  +S DRYLAI +P+ S   RT   +L A+ + W   ++ + P+L + R           +Q      C          AMD   ++  Y                    + V++ GL   R  + L          +   R+ +KVTR+++ V   F + W+P H + L       P   A  A  ++++ ++Y NS +NPI+YA +S++FR  F+
Sbjct:   12 ASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYR----------QSQLANLTVCHPAWSAPRRRAMDICTFVFSYL-------------------LPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFR 304
[Close]
BLAST of GCR317 vs. Ensembl Human
Match: GALR1 (galanin receptor 1 [Source:HGNC Symbol;Acc:HGNC:4132])

HSP 1 Score: 139.813 bits (351), Expect = 7.002e-37
Identity = 110/318 (34.59%), Postives = 167/318 (52.52%), Query Frame = 3 
Query:  219 FGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRN--GHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKI 1166
            FG+ V  + +   +FG+IF +G+LGN LVI V+ R+  G  R++TN+ I +L+ ADL +++FCIP   ++Y    W+   F+C    Y   +++  S++TL  MS DRY+AIVH   S + R    +L  V   W   I +  P   H  + +      A+NQT    +C  +              D +    +    F+FG+LLPL +I   Y  +L  + ++L N        S KK  + V+ V++ FG+SWLP HI+ L       P   A   F + A+ +AY NS +NPI+YAFLSENFR A+K+   C I
Sbjct:   27 FGIGV-ENFVTLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASPVAYHQGLFH----PRASNQT----FCWEQ------------WPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKK-SEASKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHI 322
[Close]
BLAST of GCR317 vs. Ensembl Human
Match: KISS1R (KISS1 receptor [Source:HGNC Symbol;Acc:HGNC:4510])

HSP 1 Score: 128.257 bits (321), Expect = 2.258e-32
Identity = 92/332 (27.71%), Postives = 150/332 (45.18%), Query Frame = 3 
Query:  201 SSNSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSA--------NITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQS--TYGD--PSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTC 1160
            +S+      + + + +VP  F  + ++GL+GN LVI VI R+  MR  TN  I++LA  D+TF++ C+P T  +Y   GW+  +F+C    Y+  ++V  +  TL  MS DR+   V P+ +++ RT   +L      W+    ++ P L   R+                 YC        +EA      + +A   +         LL            L R++ R     SA               KV+RLV +V++ F   W P+ +  ++Q+    G   P + A  A    A+ M+Y NS +NP+LYAFL  +FR AF++   C
Sbjct:   29 ASDGPVPSPRAVDAWLVPLFFAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLALHRL-----------SPGPRAYC--------SEAFPSRALE-RAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPC 340
[Close]
BLAST of GCR317 vs. Ensembl Human
Match: OPRK1 (opioid receptor kappa 1 [Source:HGNC Symbol;Acc:HGNC:8154])

HSP 1 Score: 127.102 bits (318), Expect = 5.667e-32
Identity = 90/305 (29.51%), Postives = 164/305 (53.77%), Query Frame = 3 
Query:  243 IIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVIL--YGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKF 1151
            +I+ A++ ++FVVGL+GN LV+ VIIR   M+ +TNI I +LA AD   +   +P   ++Y+   W + + LC I   + +  ++ S++TL +MS DRY+A+ HP+ ++++RT  ++            IIN+   + S  +    + L   + R++        V+  E    + DD  + ++ +    +F F   + +++I+  Y L++ R+        S    R+ +++TRLV+ V+  F V W P+HI  L+++      + A  + +    ++ Y NS +NPILYAFL ENF+  F+ F
Sbjct:   60 VIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALAD-ALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAK-----------IINICIWLLSSSVGISAIVLGGTKVRED--------VDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDF 344
[Close]
BLAST of GCR317 vs. Ensembl Human
Match: OPRK1 (opioid receptor kappa 1 [Source:HGNC Symbol;Acc:HGNC:8154])

HSP 1 Score: 127.102 bits (318), Expect = 5.667e-32
Identity = 90/305 (29.51%), Postives = 164/305 (53.77%), Query Frame = 3 
Query:  243 IIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVIL--YGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKF 1151
            +I+ A++ ++FVVGL+GN LV+ VIIR   M+ +TNI I +LA AD   +   +P   ++Y+   W + + LC I   + +  ++ S++TL +MS DRY+A+ HP+ ++++RT  ++            IIN+   + S  +    + L   + R++        V+  E    + DD  + ++ +    +F F   + +++I+  Y L++ R+        S    R+ +++TRLV+ V+  F V W P+HI  L+++      + A  + +    ++ Y NS +NPILYAFL ENF+  F+ F
Sbjct:   60 VIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALAD-ALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAK-----------IINICIWLLSSSVGISAIVLGGTKVRED--------VDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDF 344
[Close]
BLAST of GCR317 vs. Ensembl Celegans
Match: npr-9 (Galanin-like G-protein coupled receptor npr-9 [Source:UniProtKB/Swiss-Prot;Acc:Q23497])

HSP 1 Score: 144.436 bits (363), Expect = 2.488e-38
Identity = 107/344 (31.10%), Postives = 170/344 (49.42%), Query Frame = 3 
Query:  240 SIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLP-----------FLIHSR---VLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRI-------------SQRLNNQQSANITR-------SNKKVTRLVVSVIIAFGVSWLPLHIVFLIQS-TYGDP----SNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFL 1154
             II+P +F +I +VGL+GN LV+ V      MRNSTN LI  LA +DL F++ C+P T   Y    WI+  + C +  +    + YCSV+TL LM+ DRYLA+V+P+ S+  RT   ++ A+   +I +I   +P           F++  R    + TI    A     + Y+      + +N  + GY+                   LPL + V+LYGL+L ++              + L N+ S +  R       + +KVTRLV+ V+I + + WLPL++ F +    Y +P      V      + +  +AY NS +NPILYA +S++FR  F + +
Sbjct:   43 GIIIPTIFAVIILVGLVGNALVVIVAF-GRQMRNSTNTLIIGLAISDLMFLLLCVPFTAVDYAAPTWIFPEWTCSMINFFQHTSAYCSVWTLTLMALDRYLAVVYPVESMTLRTPRNTVIALCFIYIIIIASQIPVGRMHGIYVYDFIMEKRSTCAILTIATAEATPTMARTYF------MTFN--VFGYV-------------------LPLGISVVLYGLMLRKLWDMPRPGNSQSVGGRNLTNRDSGSSIRRRPEATAAKRKVTRLVLCVLITWALCWLPLNVCFFMSGLAYPEPLVISHGVIMVIVQIASQVLAYTNSCLNPILYALMSQSFREGFIRVM 358
[Close]
BLAST of GCR317 vs. Ensembl Celegans
Match: npr-35 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:Q7YXG8])

HSP 1 Score: 105.916 bits (263), Expect = 7.312e-25
Identity = 89/321 (27.73%), Postives = 143/321 (44.55%), Query Frame = 3 
Query:  240 SIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGY---IDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRIS--QRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANS----MAYGNSMINPILYAFLSENFRTAFKKFLTCKISPC 1175
            +++    +G +F  G+LGN  V+  +  + ++  +T+ LI SLA ADL  +  C+P TL   I+  W+W  F C +  +    T + SVYTLV ++ADRYLAI H +       R  +   ++  W+   I  +P                      N+Y  N  L+ + E   GY              F   L  F++P  +I  LY  +   +S  + L     A   R   +V  ++++VII F   WLPL+ +F     + D  +  F+   M+       M+  +S +NPI+Y   S  +R AFK  L   + PC
Sbjct:   29 TVLYTVAYGAVFFTGVLGNTFVVLAVWAHKNLNITTDYLILSLALADLFILWICLPTTLINSIFTEWLWGQFFCRLSTWANASTSFASVYTLVAVTADRYLAICHTLKYNTSWDREYTKYVIFAVWLVAAIFGIP----------------------NWY--NYDLIVWQEGSYGYRLCTSQTDQKLYFLFVNLLLAFIVPFGLISGLYTRIFITVSTHRSLAVDARAREDRVKLRVATMMLTVIIVFACCWLPLYCIFTYFFFFADQRSDLFQITSMLIRPIFQWMSLLSSSLNPIIYIAYSHKYRRAFKSIL---LMPC 322
[Close]
BLAST of GCR317 vs. Ensembl Celegans
Match: npr-22 (Neuropeptide receptor 22 [Source:UniProtKB/Swiss-Prot;Acc:Q59E83])

HSP 1 Score: 106.301 bits (264), Expect = 8.779e-25
Identity = 94/319 (29.47%), Postives = 156/319 (48.90%), Query Frame = 3 
Query:  261 FGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLT---LSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVIL----YGLLLY--RISQRLNNQQSANITRSNKKVTRLVVSVII---AFGVSWLPLHIVF-LIQSTYGDPSNVAFRAF-HMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKISPC 1175
            + I+ V  + GN LVI VI+    +R +TNILI +LA ADL   VFCIP +   + IY  Q W++ + +C +  +L  + V+ S +TLV++S DR++AI+  +T     TR R+L  V  +WI  I++ LP L  +R                 ++     L N  E    + D  + +   Y +  L    +    ++I+     G+ ++  R+    N      I   ++ V +LV  VI+    F + WLPL I+  +I   Y D ++  +  +    A+ +A  +SM+NPI+Y   +  FR  F  F + K+ PC
Sbjct:   57 YSILCVCCVYGNVLVILVIVYFKRLRTATNILILNLAVADLLISVFCIPFSYWQVLIYDDQRWLFGSMMCSLLAFLQAMAVFLSAWTLVVISFDRWMAIMFLLTPNIRITRRRALYLVAATWIFSILMALPLLFTTR-----------------FFEDQDGLPNCGENWTYFGDSGEQVRKVYSSMVLILQYVVPQAVLIITYTHIGIKMWNSRVPGMQNGATKKMIVDRHESVKKLVPMVILISALFALCWLPLLILINVIPEFYPDINSWGYILYLWWFAHGLAMSHSMVNPIIYFIRNARFREGF-CFFSSKLLPC 357
[Close]
BLAST of GCR317 vs. Ensembl Celegans
Match: npr-22 (Neuropeptide receptor 22 [Source:UniProtKB/Swiss-Prot;Acc:Q59E83])

HSP 1 Score: 105.916 bits (263), Expect = 1.094e-24
Identity = 94/319 (29.47%), Postives = 156/319 (48.90%), Query Frame = 3 
Query:  261 FGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLT---LSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVIL----YGLLLY--RISQRLNNQQSANITRSNKKVTRLVVSVII---AFGVSWLPLHIVF-LIQSTYGDPSNVAFRAF-HMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKISPC 1175
            + I+ V  + GN LVI VI+    +R +TNILI +LA ADL   VFCIP +   + IY  Q W++ + +C +  +L  + V+ S +TLV++S DR++AI+  +T     TR R+L  V  +WI  I++ LP L  +R                 ++     L N  E    + D  + +   Y +  L    +    ++I+     G+ ++  R+    N      I   ++ V +LV  VI+    F + WLPL I+  +I   Y D ++  +  +    A+ +A  +SM+NPI+Y   +  FR  F  F + K+ PC
Sbjct:   57 YSILCVCCVYGNVLVILVIVYFKRLRTATNILILNLAVADLLISVFCIPFSYWQVLIYDDQRWLFGSMMCSLLAFLQAMAVFLSAWTLVVISFDRWMAIMFLLTPNIRITRRRALYLVAATWIFSILMALPLLFTTR-----------------FFEDQDGLPNCGENWTYFGDSGEQVRKVYSSMVLILQYVVPQAVLIITYTHIGIKMWNSRVPGMQNGATKKMIVDRHESVKKLVPMVILISALFALCWLPLLILINVIPEFYPDINSWGYILYLWWFAHGLAMSHSMVNPIIYFIRNARFREGF-CFFSSKLLPC 357
[Close]
BLAST of GCR317 vs. Ensembl Celegans
Match: npr-34 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:G5EDR6])

HSP 1 Score: 93.9745 bits (232), Expect = 2.730e-20
Identity = 47/140 (33.57%), Postives = 82/140 (58.57%), Query Frame = 3 
Query:  228 QVLTSIIVPA-LFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLP 644
            + L  I +P  L+  +F+VG +GN +VI V+ R   MRN TNI ++SL+ ADL  I FC+P+    Y+   W    F C    Y+   T +CSV T+ ++S +R+LAI +P+ ++ + +  R+   + + W++  ++ +P
Sbjct:   67 EELFEIALPGFLYLTVFLVGTIGNSMVIFVVNRFKRMRNVTNIFLASLSTADLCLIWFCVPIMFMKYMSHTWSMGRFACYSVHYIQQFTCFCSVLTMTMISFERFLAIAYPMRNIWFSSIGRAKKVILLIWMSSAVLAVP 206

HSP 2 Score: 55.4546 bits (132), Expect = 5.003e-8
Identity = 32/90 (35.56%), Postives = 55/90 (61.11%), Query Frame = 3 
Query:  891 NNQQSANITRSNKK-VTRLVVSVIIAFGVSWLPLHIVFLIQSTYG---DPSNV-AFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFK 1145
            +N ++  +  +NKK + ++++S++  + V WLP  IV  + +++G     SN    +   M  N++ Y  S INPILYAF+S+NFR+ FK
Sbjct:  327 SNHRNNRVAEANKKQIVQMLISIVCMYTVCWLPT-IVDELLTSFGYICRTSNTQTLKHMRMGFNALTYCQSCINPILYAFISQNFRSTFK 415
[Close]
BLAST of GCR317 vs. Ensembl Fly
Match: AstA-R1 (gene:FBgn0266429 transcript:FBtr0333798)

HSP 1 Score: 186.037 bits (471), Expect = 3.581e-54
Identity = 120/329 (36.47%), Postives = 194/329 (58.97%), Query Frame = 3 
Query:  207 NSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPF-LIHSRVLYTIPVKLANNQTRKNYYCGNKK---LVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNK-KVTRLVVSVIIAFGVSWLPLHIVFLIQS--TYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKISP 1172
            ++ +  ++ + S IVP  FGII   GLLGNGLVI V++ N  MR++TN+LI +LA +D+ F++FC+P T + Y+   W + N  C   QY+  +T +CSVYTLVLMS DR+LA+VHP+TS++ RT   +  A+  +WI ++   +P  L HS  +Y    +   N      +   ++   LV +  +   ++  Y A               PL++I  LY  +L R+ +     + +  +R  K +VTR+VV V++AF + WLP+H++ ++++   YG  S+++     ++++ +AY NS INPILYAFLS+NFR AF+K + C   P
Sbjct:   63 DAESVALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVALSHSVRIY----QYHGNAGTACVFSTEEEIWSLVGFQVSF--FLSSYVA---------------PLTLICFLYMGMLARLWKSAPGCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGG-SHLSV-IIQIISHVVAYTNSCINPILYAFLSDNFRKAFRKVVWCGSPP 368
[Close]
BLAST of GCR317 vs. Ensembl Fly
Match: AstA-R1 (gene:FBgn0266429 transcript:FBtr0070575)

HSP 1 Score: 186.037 bits (471), Expect = 3.581e-54
Identity = 120/329 (36.47%), Postives = 194/329 (58.97%), Query Frame = 3 
Query:  207 NSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPF-LIHSRVLYTIPVKLANNQTRKNYYCGNKK---LVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNK-KVTRLVVSVIIAFGVSWLPLHIVFLIQS--TYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKISP 1172
            ++ +  ++ + S IVP  FGII   GLLGNGLVI V++ N  MR++TN+LI +LA +D+ F++FC+P T + Y+   W + N  C   QY+  +T +CSVYTLVLMS DR+LA+VHP+TS++ RT   +  A+  +WI ++   +P  L HS  +Y    +   N      +   ++   LV +  +   ++  Y A               PL++I  LY  +L R+ +     + +  +R  K +VTR+VV V++AF + WLP+H++ ++++   YG  S+++     ++++ +AY NS INPILYAFLS+NFR AF+K + C   P
Sbjct:   63 DAESVALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVALSHSVRIY----QYHGNAGTACVFSTEEEIWSLVGFQVSF--FLSSYVA---------------PLTLICFLYMGMLARLWKSAPGCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGG-SHLSV-IIQIISHVVAYTNSCINPILYAFLSDNFRKAFRKVVWCGSPP 368
[Close]
BLAST of GCR317 vs. Ensembl Fly
Match: AstA-R2 (gene:FBgn0039595 transcript:FBtr0085316)

HSP 1 Score: 163.31 bits (412), Expect = 6.515e-46
Identity = 118/308 (38.31%), Postives = 174/308 (56.49%), Query Frame = 3 
Query:  246 IVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRI-SQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFR-AFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCK 1163
            IV   FG+I + G  GN LVI V++ N +MR++TN++I +LA ADL F++ CIP T + Y+   W +  F C   QYL  +T + S+YTLVLMS DR+LA+VHPI S   RT N +L A+   WI ++++++P      V       + +   +KN   G               +D+     +  TFF+  +LLPL +I  LY  ++ R+  Q    + S    R  K+VTRLVV V+IAF   WLP+ ++ L++S     +N   +    + A ++AY +S INP+LYAFLSENFR AF K + C 
Sbjct:   40 IVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDV-------VVDYDAKKNITYGMCTFTT---------NDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKAVNCS 331
[Close]
BLAST of GCR317 vs. Ensembl Fly
Match: AstA-R2 (gene:FBgn0039595 transcript:FBtr0336790)

HSP 1 Score: 163.31 bits (412), Expect = 6.515e-46
Identity = 118/308 (38.31%), Postives = 174/308 (56.49%), Query Frame = 3 
Query:  246 IVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRI-SQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFR-AFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCK 1163
            IV   FG+I + G  GN LVI V++ N +MR++TN++I +LA ADL F++ CIP T + Y+   W +  F C   QYL  +T + S+YTLVLMS DR+LA+VHPI S   RT N +L A+   WI ++++++P      V       + +   +KN   G               +D+     +  TFF+  +LLPL +I  LY  ++ R+  Q    + S    R  K+VTRLVV V+IAF   WLP+ ++ L++S     +N   +    + A ++AY +S INP+LYAFLSENFR AF K + C 
Sbjct:   40 IVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDV-------VVDYDAKKNITYGMCTFTT---------NDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKAVNCS 331
[Close]
BLAST of GCR317 vs. Ensembl Fly
Match: AstA-R2 (gene:FBgn0039595 transcript:FBtr0308641)

HSP 1 Score: 160.999 bits (406), Expect = 3.559e-45
Identity = 118/305 (38.69%), Postives = 173/305 (56.72%), Query Frame = 3 
Query:  246 IVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRI-SQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFR-AFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFL 1154
            IV   FG+I + G  GN LVI V++ N +MR++TN++I +LA ADL F++ CIP T + Y+   W +  F C   QYL  +T + S+YTLVLMS DR+LA+VHPI S   RT N +L A+   WI ++++++P      V       + +   +KN   G               +D+     +  TFF+  +LLPL +I  LY  ++ R+  Q    + S    R  K+VTRLVV V+IAF   WLP+ ++ L++S     +N   +    + A ++AY +S INP+LYAFLSENFR AF K L
Sbjct:   40 IVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDV-------VVDYDAKKNITYGMCTFTT---------NDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKGL 328
[Close]
BLAST of GCR317 vs. Ensembl Zebrafish
Match: galr1b (galanin receptor 1b [Source:ZFIN;Acc:ZDB-GENE-140624-1])

HSP 1 Score: 171.4 bits (433), Expect = 6.358e-49
Identity = 112/322 (34.78%), Postives = 171/322 (53.11%), Query Frame = 3 
Query:  204 SNSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVI--IRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCK 1163
              +  FG +V   +IVP +FG IF +G++GN LV+ VI  I++   R++TNI I +L+ ADL+F++FC+P   +IY    WI+  FLC    Y   +++  S++TLV MS DRY+A+V    S   R R  +L  V + W+   I  +P   H ++L   P   A N T    +C       + E +  +   YK                   +I   Y  +LY + +++ N  S    RS +K  + V+ V+ AF + W+P HI+ +       P N A  AF ++++ +AYGNS +NPILYAFLSENFR A K+  TC+
Sbjct:   24 QTTDTFGPEV---VIVPVIFGCIFFLGIIGNTLVMVVIGKIKSRRSRSTTNIFILNLSIADLSFLLFCVPFQATIYSLPEWIFGAFLCKFVHYFVMVSMLVSIFTLVAMSVDRYIAVVLSKKSPCIRNRRNALIGVCVIWMLSFIFAVPVAQH-QILTDHP--KAPNST----FCWEI----WTERVAKH--TYKVTILVIGYLLPLL------LITCCYAKVLYHLHKKIKN-MSKKSERSKRKTAQTVLLVVAAFLICWMPHHIIAMWVEFGQFPLNDASFAFRIISHCLAYGNSCVNPILYAFLSENFRKACKQVFTCR 322
[Close]
BLAST of GCR317 vs. Ensembl Zebrafish
Match: galr2b (galanin receptor 2b [Source:ZFIN;Acc:ZDB-GENE-131121-48])

HSP 1 Score: 162.925 bits (411), Expect = 1.798e-45
Identity = 101/312 (32.37%), Postives = 174/312 (55.77%), Query Frame = 3 
Query:  240 SIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMR-NSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGD-PSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKIS 1169
            S+IV  +F +IF++G +GN LV+AV++R+G +  N+TN+ I +L+ AD  FI+FC+P   +IY  +GW++ +F+C +  +   LT+Y S +TL  +S DRYLAI +P+ S   RT   ++ A+ + W   ++   P+L +    Y +     +N     +   N+K+++    + GY+                  +L +S+        L+     L+    +   R+ +KVT++++ V + F + WLP H+V L    YGD P N    AF ++++ MAY NS +NPI+YA +S++FR  FKK  +C +S
Sbjct:   26 SVIVSVVFSLIFLLGTIGNSLVLAVLLRSGQVGYNTTNLFILNLSVADFFFIIFCVPFQATIYSLEGWVFGSFMCKVVHFFINLTMYASSFTLAAVSVDRYLAIRYPLRSRELRTPCNAVVAMVVIWGLSLVFAGPYLSY----YDLIDFENSNVCVPGWEEHNRKVLDTCTFVFGYV----------------IPVLIVSLSYTRTIKYLWTAVDPLDGMSESK--RAKRKVTKMIIIVTVLFCICWLPYHVVILCY-LYGDFPFNQTTYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFKKVFSCILS 314
[Close]
BLAST of GCR317 vs. Ensembl Zebrafish
Match: galr2b (galanin receptor 2b [Source:ZFIN;Acc:ZDB-GENE-131121-48])

HSP 1 Score: 162.925 bits (411), Expect = 1.798e-45
Identity = 101/312 (32.37%), Postives = 174/312 (55.77%), Query Frame = 3 
Query:  240 SIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMR-NSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGD-PSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKIS 1169
            S+IV  +F +IF++G +GN LV+AV++R+G +  N+TN+ I +L+ AD  FI+FC+P   +IY  +GW++ +F+C +  +   LT+Y S +TL  +S DRYLAI +P+ S   RT   ++ A+ + W   ++   P+L +    Y +     +N     +   N+K+++    + GY+                  +L +S+        L+     L+    +   R+ +KVT++++ V + F + WLP H+V L    YGD P N    AF ++++ MAY NS +NPI+YA +S++FR  FKK  +C +S
Sbjct:   26 SVIVSVVFSLIFLLGTIGNSLVLAVLLRSGQVGYNTTNLFILNLSVADFFFIIFCVPFQATIYSLEGWVFGSFMCKVVHFFINLTMYASSFTLAAVSVDRYLAIRYPLRSRELRTPCNAVVAMVVIWGLSLVFAGPYLSY----YDLIDFENSNVCVPGWEEHNRKVLDTCTFVFGYV----------------IPVLIVSLSYTRTIKYLWTAVDPLDGMSESK--RAKRKVTKMIIIVTVLFCICWLPYHVVILCY-LYGDFPFNQTTYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFKKVFSCILS 314
[Close]
BLAST of GCR317 vs. Ensembl Zebrafish
Match: galr2a (galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-130603-37])

HSP 1 Score: 159.458 bits (402), Expect = 2.311e-44
Identity = 101/319 (31.66%), Postives = 165/319 (51.72%), Query Frame = 3 
Query:  240 SIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMR-NSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMD------GYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNN-----QQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTC 1160
            S+I+  +F +IF+VG +GN LV+AV+IRNG M   STN+ I +L  ADL FIVFC+PL  +IY    W++  F+C    ++ +LT+Y S++TL  +S DRYLAI +P+ S   RT   +LT++ + W   +  + P+L + + +                 C     V++ +AMD      GY+                       + V++ G+   R  + L       Q  +   ++ +KVT++++ V + F + WLP H+V L       P N       ++++ +AY NS +NPI+YA +S++FR  FKK   C
Sbjct:   17 SVIISLIFSMIFLVGTVGNCLVLAVLIRNGQMNTKSTNLFILNLGLADLCFIVFCVPLQATIYTMDEWVFGAFVCKAVHFIIYLTMYASIFTLAAVSLDRYLAIRYPLRSRETRTPRNALTSISLVWALSLFFSSPYLSYYQQM----------DLDGTTVCIPAWSVHHRQAMDICTFIFGYL-----------------------IPVLILGITYARTIRYLWTSVDPMQDMSESRKAKRKVTKMIIIVAVLFCLCWLPHHLVILCMWFGHFPLNHTTYVLRILSHLVAYANSCLNPIVYALVSKHFRKGFKKVFGC 302
[Close]
BLAST of GCR317 vs. Ensembl Zebrafish
Match: galr2a (galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-130603-37])

HSP 1 Score: 159.458 bits (402), Expect = 2.596e-44
Identity = 101/321 (31.46%), Postives = 166/321 (51.71%), Query Frame = 3 
Query:  234 LTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMR-NSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMD------GYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNN-----QQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTC 1160
            + S+I+  +F +IF+VG +GN LV+AV+IRNG M   STN+ I +L  ADL FIVFC+PL  +IY    W++  F+C    ++ +LT+Y S++TL  +S DRYLAI +P+ S   RT   +LT++ + W   +  + P+L + + +                 C     V++ +AMD      GY+                       + V++ G+   R  + L       Q  +   ++ +KVT++++ V + F + WLP H+V L       P N       ++++ +AY NS +NPI+YA +S++FR  FKK   C
Sbjct:   16 VESVIISLIFSMIFLVGTVGNCLVLAVLIRNGQMNTKSTNLFILNLGLADLCFIVFCVPLQATIYTMDEWVFGAFVCKAVHFIIYLTMYASIFTLAAVSLDRYLAIRYPLRSRETRTPRNALTSISLVWALSLFFSSPYLSYYQQM----------DLDGTTVCIPAWSVHHRQAMDICTFIFGYL-----------------------IPVLILGITYARTIRYLWTSVDPMQDMSESRKAKRKVTKMIIIVAVLFCLCWLPHHLVILCMWFGHFPLNHTTYVLRILSHLVAYANSCLNPIVYALVSKHFRKGFKKVFGC 303
[Close]
BLAST of GCR317 vs. Ensembl Xenopus
Match: ENSXETT00000041298.1 (galanin receptor 3 [Source:NCBI gene;Acc:100488248])

HSP 1 Score: 176.407 bits (446), Expect = 1.201e-50
Identity = 108/326 (33.13%), Postives = 180/326 (55.21%), Query Frame = 3 
Query:  207 NSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMR-NSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLY--TIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYR----ISQRLNNQQSANITRSNK-KVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTC 1160
            NSS         IIVP +F +IF +G +GNGLV+AV++RNG  + N+TN+ I +L  ADL FI+ C+P   +IY   GW++  FLC    +  +L++Y S +TL  +S DRYLAI +P+ S + RT   +L A+ + W   I+   P+L +  ++    +P+ + N + R+      +K+++ +  + GY+                       + V++ GL   R    +   ++  ++A+ +R  K KVT++++ V + F + WLP H+V L       P N A  AF +V++ M+Y NS +NPI+YA +S++FR  FK+  TC
Sbjct:    6 NSSVSSELPPGGIIVPVVFSLIFALGTVGNGLVLAVLLRNGQTKYNTTNLFILNLGVADLCFILLCVPFQATIYTLDGWLFGAFLCKAVHFSIYLSMYASSFTLAAVSVDRYLAIRYPLKSRDLRTSRNALAAIGVIWALSILFAGPYLSYYHIILYNQVPICIPNWEDRR------RKIMDVSTFVFGYL-----------------------LPVLILGLSYARTICFLWTSVDPVKTASESRKAKHKVTKMIIIVAVLFCICWLPHHLVILCFWFGHFPFNKATYAFRLVSHCMSYANSCLNPIVYALISKHFRKRFKQVFTC 302
[Close]
BLAST of GCR317 vs. Ensembl Xenopus
Match: sp3 (Sp3 transcription factor [Source:Xenbase;Acc:XB-GENE-977158])

HSP 1 Score: 164.851 bits (416), Expect = 4.774e-46
Identity = 99/325 (30.46%), Postives = 176/325 (54.15%), Query Frame = 3 
Query:  207 NSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGH-MRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNN-----QQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGD-PSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTC 1160
            NSS   +    SI+VP +F +IF++G +GN LV+AV++R+G    N+TN+ I +L+ AD++FI+FC+P   +IY  + W++  F+C    +  +LT+Y S +TL  +S DRYLAI +P+ S   RT   ++  + I W   ++   P+L +    Y +    +++     +    +K+++    + GY+                       + V++  L   R  + L       +  +   ++ +KVT++++ V + F + WLP H+V +    YGD P N A  AF ++++ MAY NS +NPI+YA +S++FR  F+K  +C
Sbjct:   15 NSSDLSLFSPASIVVPVIFSLIFLLGTVGNSLVLAVLLRSGQRTHNTTNLFILNLSVADVSFIIFCVPFQATIYSLEDWVFGAFMCKAVHFFIYLTMYASSFTLAAVSVDRYLAIRYPLRSRELRTPCNAIATMAIIWGLSVVFAGPYLSY----YDLMDYESSHICMPGWKERTRKIMDTGTFIVGYV-----------------------IPVLIVSLSYTRTIKYLWTAVDPLEDMSESKKAKRKVTKMIIIVTVLFCLCWLPHHVVVMCY-LYGDFPFNQATYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFQKVFSC 311
[Close]
BLAST of GCR317 vs. Ensembl Xenopus
Match: sp3 (Sp3 transcription factor [Source:Xenbase;Acc:XB-GENE-977158])

HSP 1 Score: 164.851 bits (416), Expect = 7.299e-46
Identity = 99/325 (30.46%), Postives = 176/325 (54.15%), Query Frame = 3 
Query:  207 NSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGH-MRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNN-----QQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGD-PSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTC 1160
            NSS   +    SI+VP +F +IF++G +GN LV+AV++R+G    N+TN+ I +L+ AD++FI+FC+P   +IY  + W++  F+C    +  +LT+Y S +TL  +S DRYLAI +P+ S   RT   ++  + I W   ++   P+L +    Y +    +++     +    +K+++    + GY+                       + V++  L   R  + L       +  +   ++ +KVT++++ V + F + WLP H+V +    YGD P N A  AF ++++ MAY NS +NPI+YA +S++FR  F+K  +C
Sbjct:   38 NSSDLSLFSPASIVVPVIFSLIFLLGTVGNSLVLAVLLRSGQRTHNTTNLFILNLSVADVSFIIFCVPFQATIYSLEDWVFGAFMCKAVHFFIYLTMYASSFTLAAVSVDRYLAIRYPLRSRELRTPCNAIATMAIIWGLSVVFAGPYLSY----YDLMDYESSHICMPGWKERTRKIMDTGTFIVGYV-----------------------IPVLIVSLSYTRTIKYLWTAVDPLEDMSESKKAKRKVTKMIIIVTVLFCLCWLPHHVVVMCY-LYGDFPFNQATYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFQKVFSC 334
[Close]
BLAST of GCR317 vs. Ensembl Xenopus
Match: GALR2 (galanin receptor 2 [Source:NCBI gene;Acc:100486593])

HSP 1 Score: 156.377 bits (394), Expect = 6.617e-43
Identity = 98/312 (31.41%), Postives = 163/312 (52.24%), Query Frame = 3 
Query:  240 SIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNN-----QQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTC 1160
            S+++P L+ +IF+VG +GN LV+AV++RNG + N+TN+ I +L  ADL FI+FC+P   +IY    W++  F+C    +  +LT+Y S +TL  +S DRYLAI +P+ S   RT   +L A+ + W   ++ + P+L      Y    +L+N        C      +Y  AMD                 L  F     + V++  L   R  + L       +  +   R+ ++VTR+++ V + F + WLP H+V L       P N    A  ++++ ++Y NS +NP++YA +S++FR  F+K   C
Sbjct:   17 SVLIPVLYSLIFLVGTVGNSLVLAVLLRNGKVNNTTNLFILNLGVADLCFIIFCVPFQATIYTLDSWVFGPFMCKAVHFFIYLTMYASSFTLTTVSLDRYLAIRYPLRSRELRTPKNALLAITLIWSLSLVFSGPYLS-----YYQEFQLSNLTV-----CHPVWQDSYRRAMD-----------------LCTFAFSYVIPVLILSLTYARTIRYLWTAVDPIEDMSESKRAKRRVTRMIIIVAVLFCLCWLPHHLVILCVWFGYFPLNNFTYALRILSHLVSYANSCVNPVVYALVSKHFRKGFRKIFRC 301
[Close]
BLAST of GCR317 vs. Ensembl Xenopus
Match: lmod3 (leiomodin 3 [Source:Xenbase;Acc:XB-GENE-5737414])

HSP 1 Score: 150.214 bits (378), Expect = 9.112e-41
Identity = 109/321 (33.96%), Postives = 166/321 (51.71%), Query Frame = 3 
Query:  234 LTSIIVPALFGIIFVVGLLGNGLVIAVIIRN--GHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYC-------GNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKIS 1169
            + ++I   +FG+IF +G+LGN LVI V+ RN  G  R++TNI I +L+ ADL +++FCIP   ++Y+   W+   F+C    Y   +++  S++TL  MS DRY+AIVH   S   R    +L  V + WI  I +  P   +  ++Y       NNQT    +C         K++      + GY+                   LPL +I   Y  +L  + ++L N        S KK  + V+ V++ FG+SWLP H++ L       P   A   F +VA+ +AY NS +NPI+YAFLSENFR A+K+   C+I 
Sbjct:   35 IDNVITLVVFGMIFALGVLGNSLVITVLARNKPGKPRSTTNIFILNLSIADLAYLLFCIPFQSTVYVLPTWVLGAFICKFIHYFFTVSMLVSIFTLSAMSVDRYVAIVHSRRSSAIRVSRNALVGVIVIWILSIAMASPVAYNQGLVY------KNNQT----FCWESWPNAQQKRIYVVCTFVFGYL-------------------LPLLLISFCYAKVLNHLHKKLRNMSKK-SEASKKKTAQTVLVVVVVFGISWLPHHVIHLWVEYGSFPLTQASFVFRIVAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCQIG 325
[Close]
BLAST of GCR317 vs. Ensembl Mouse
Match: Galr1 (galanin receptor 1 [Source:MGI Symbol;Acc:MGI:1096364])

HSP 1 Score: 146.362 bits (368), Expect = 1.818e-39
Identity = 111/333 (33.33%), Postives = 169/333 (50.75%), Query Frame = 3 
Query:  183 NVEFPKSSNSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRN--GHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNK---KLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKI 1166
            + E P   +   FG+ V  + I   +FG+IF +G+LGN LVI V+ R+  G  R++TN+ I +L+ ADL +++FCIP   ++Y    W+   F+C    Y   +++  S++TL  MS DRY+AIVH   S + R    +L  V   W   I +  P   H R+ +       +NQT    +C  +   KL      +  ++  Y               LLPL +I   Y  +L  + ++L N        S KK  + V+ V++ FG+SWLP H+V L       P   A   F + A+ +AY NS +NPI+YAFLSENFR A+K+   C +
Sbjct:   15 DPEPPAPESRPLFGIGV-ENFITLVVFGLIFAMGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASPVAYHQRLFHR-----DSNQT----FCWEQWPNKLHKKAYVVCTFVFGY---------------LLPLLLICFCYAKVLNHLHKKLKNMSKK-SEASKKKTAQTVLVVVVVFGISWLPHHVVHLWAEFGAFPLTPASFFFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHV 321
[Close]
BLAST of GCR317 vs. Ensembl Mouse
Match: Galr2 (galanin receptor 2 [Source:MGI Symbol;Acc:MGI:1337018])

HSP 1 Score: 145.976 bits (367), Expect = 3.384e-39
Identity = 98/320 (30.63%), Postives = 170/320 (53.12%), Query Frame = 3 
Query:  198 KSSNSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMD--GYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANIT-RSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKK 1148
             SS     G Q   +++VP  F +IF+VG +GN LV+AV++R G   ++TN+ I +L  ADL FI+ C+P   +IY    W++ + LC    +L +LT++ S +TL  +S DRYLAI +P+ S   RT   +L A+ + W   ++ + P+L      Y    +LAN       +   ++      AMD   ++  Y               LLP+ ++ + Y   L+ + + ++   + + + R+ +KVTR++V V + F + W+P H + L       P   A  A  ++++ ++Y NS +NPI+YA +S++FR  F+K
Sbjct:   11 DSSQEGGGGWQP-EAVLVPLFFALIFLVGAVGNALVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLS-----YYSQSQLANLTVCHPAWSAPRR-----RAMDLCTFVFSY---------------LLPVLVLSLTYARTLHYLWRTVDPVAAGSGSQRAKRKVTRMIVIVAVLFCLCWMPHHALILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRK 304
[Close]
BLAST of GCR317 vs. Ensembl Mouse
Match: Oprk1 (opioid receptor, kappa 1 [Source:MGI Symbol;Acc:MGI:97439])

HSP 1 Score: 134.42 bits (337), Expect = 7.487e-35
Identity = 86/305 (28.20%), Postives = 164/305 (53.77%), Query Frame = 3 
Query:  243 IIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVIL--YGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKF 1151
            +I+ A++ ++FVVGL+GN LV+ VIIR   M+ +TNI I +LA AD   +   +P   ++Y+   W + + LC I   + +  ++ S++TL +MS DRY+A+ HP+ ++++RT  ++            IIN+   + +  +    + L   + R++        V+  E    + DD  + ++ +    +F F   + +++I+  Y L++ R+        S    R+ +++T+LV+ V+  F + W P+HI  L+++      + A  + +    ++ Y NS +NP+LYAFL ENF+  F+ F
Sbjct:   60 VIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALAD-ALVTTTMPFQSAVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAK-----------IINICIWLLASSVGISAIVLGGTKVRED--------VDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDF 344
[Close]
BLAST of GCR317 vs. Ensembl Mouse
Match: Oprk1 (opioid receptor, kappa 1 [Source:MGI Symbol;Acc:MGI:97439])

HSP 1 Score: 134.42 bits (337), Expect = 7.487e-35
Identity = 86/305 (28.20%), Postives = 164/305 (53.77%), Query Frame = 3 
Query:  243 IIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVIL--YGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKF 1151
            +I+ A++ ++FVVGL+GN LV+ VIIR   M+ +TNI I +LA AD   +   +P   ++Y+   W + + LC I   + +  ++ S++TL +MS DRY+A+ HP+ ++++RT  ++            IIN+   + +  +    + L   + R++        V+  E    + DD  + ++ +    +F F   + +++I+  Y L++ R+        S    R+ +++T+LV+ V+  F + W P+HI  L+++      + A  + +    ++ Y NS +NP+LYAFL ENF+  F+ F
Sbjct:   60 VIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALAD-ALVTTTMPFQSAVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAK-----------IINICIWLLASSVGISAIVLGGTKVRED--------VDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDF 344
[Close]
BLAST of GCR317 vs. Ensembl Mouse
Match: Oprk1 (opioid receptor, kappa 1 [Source:MGI Symbol;Acc:MGI:97439])

HSP 1 Score: 134.42 bits (337), Expect = 7.487e-35
Identity = 86/305 (28.20%), Postives = 164/305 (53.77%), Query Frame = 3 
Query:  243 IIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVIL--YGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKF 1151
            +I+ A++ ++FVVGL+GN LV+ VIIR   M+ +TNI I +LA AD   +   +P   ++Y+   W + + LC I   + +  ++ S++TL +MS DRY+A+ HP+ ++++RT  ++            IIN+   + +  +    + L   + R++        V+  E    + DD  + ++ +    +F F   + +++I+  Y L++ R+        S    R+ +++T+LV+ V+  F + W P+HI  L+++      + A  + +    ++ Y NS +NP+LYAFL ENF+  F+ F
Sbjct:   60 VIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALAD-ALVTTTMPFQSAVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAK-----------IINICIWLLASSVGISAIVLGGTKVRED--------VDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDF 344
[Close]
BLAST of GCR317 vs. UniProt/SwissProt
Match: sp|Q8WPA2|AR_BOMMO (Allatostatin-A receptor OS=Bombyx mori OX=7091 GN=AR PE=2 SV=1)

HSP 1 Score: 183.726 bits (465), Expect = 1.473e-52
Identity = 115/313 (36.74%), Postives = 181/313 (57.83%), Query Frame = 3 
Query:  225 MQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRI-SQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTC 1160
            ++ + S +VP  FG I +VGL+GN LV+ V+  N  MR++TN+LI +LA ADL F++FC+P T + Y+   W + ++ C + QY   +T + SVYTLVLMS DR++A+VHPI S++ RT   +L A+   W+ ++               IPV + + +   +Y+  N     + E   GY     +      +FFL  +++PL++I +LY  +L R+       + SA   R  KKVTR+VV V++ F V W P+ I+ L+++              +V++ +AY NS +NP+LYAFLSENFR AF+K + C
Sbjct:   37 LEKVVSRVVPIFFGFIGIVGLVGNALVVLVVAANPGMRSTTNLLIINLAVADLLFVIFCVPFTATDYVMPRWPFGDWWCKVVQYFIVVTAHASVYTLVLMSLDRFMAVVHPIASMSIRTEKNALLAIACIWVVILTT------------AIPVGICHGEREYSYFNRNHSSCVFLEE-RGY-----SKLGFQMSFFLSSYVIPLALISVLYMCMLTRLWKSAPGGRVSAESRRGRKKVTRMVVVVVVVFAVCWCPIQIILLVKALNKYHITYFTVTAQIVSHVLAYMNSCVNPVLYAFLSENFRVAFRKVMYC 331
[Close]
BLAST of GCR317 vs. UniProt/SwissProt
Match: sp|E7F7V7|GAL2B_DANRE (Galanin receptor 2b OS=Danio rerio OX=7955 GN=galr2b PE=2 SV=1)

HSP 1 Score: 162.925 bits (411), Expect = 1.357e-44
Identity = 101/312 (32.37%), Postives = 174/312 (55.77%), Query Frame = 3 
Query:  240 SIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMR-NSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGD-PSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKIS 1169
            S+IV  +F +IF++G +GN LV+AV++R+G +  N+TN+ I +L+ AD  FI+FC+P   +IY  +GW++ +F+C +  +   LT+Y S +TL  +S DRYLAI +P+ S   RT   ++ A+ + W   ++   P+L +    Y +     +N     +   N+K+++    + GY+                  +L +S+        L+     L+    +   R+ +KVT++++ V + F + WLP H+V L    YGD P N    AF ++++ MAY NS +NPI+YA +S++FR  FKK  +C +S
Sbjct:   26 SVIVSVVFSLIFLLGTIGNSLVLAVLLRSGQVGYNTTNLFILNLSVADFFFIIFCVPFQATIYSLEGWVFGSFMCKVVHFFINLTMYASSFTLAAVSVDRYLAIRYPLRSRELRTPCNAVVAMVVIWGLSLVFAGPYLSY----YDLIDFENSNVCVPGWEEHNRKVLDTCTFVFGYV----------------IPVLIVSLSYTRTIKYLWTAVDPLDGMSESK--RAKRKVTKMIIIVTVLFCICWLPYHVVILCY-LYGDFPFNQTTYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFKKVFSCILS 314
[Close]
BLAST of GCR317 vs. UniProt/SwissProt
Match: sp|F1R332|GAL2A_DANRE (Galanin receptor 2a OS=Danio rerio OX=7955 GN=galr2a PE=2 SV=2)

HSP 1 Score: 159.458 bits (402), Expect = 1.960e-43
Identity = 101/321 (31.46%), Postives = 166/321 (51.71%), Query Frame = 3 
Query:  234 LTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMR-NSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMD------GYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNN-----QQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTC 1160
            + S+I+  +F +IF+VG +GN LV+AV+IRNG M   STN+ I +L  ADL FIVFC+PL  +IY    W++  F+C    ++ +LT+Y S++TL  +S DRYLAI +P+ S   RT   +LT++ + W   +  + P+L + + +                 C     V++ +AMD      GY+                       + V++ G+   R  + L       Q  +   ++ +KVT++++ V + F + WLP H+V L       P N       ++++ +AY NS +NPI+YA +S++FR  FKK   C
Sbjct:   16 VESVIISLIFSMIFLVGTVGNCLVLAVLIRNGQMNTKSTNLFILNLGLADLCFIVFCVPLQATIYTMDEWVFGAFVCKAVHFIIYLTMYASIFTLAAVSLDRYLAIRYPLRSRETRTPRNALTSISLVWALSLFFSSPYLSYYQQM----------DLDGTTVCIPAWSVHHRQAMDICTFIFGYL-----------------------IPVLILGITYARTIRYLWTSVDPMQDMSESRKAKRKVTKMIIIVAVLFCLCWLPHHLVILCMWFGHFPLNHTTYVLRILSHLVAYANSCLNPIVYALVSKHFRKGFKKVFGC 303
[Close]
BLAST of GCR317 vs. UniProt/SwissProt
Match: sp|P56479|GALR1_MOUSE (Galanin receptor type 1 OS=Mus musculus OX=10090 GN=Galr1 PE=2 SV=1)

HSP 1 Score: 146.362 bits (368), Expect = 1.271e-38
Identity = 111/333 (33.33%), Postives = 169/333 (50.75%), Query Frame = 3 
Query:  183 NVEFPKSSNSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRN--GHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNK---KLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKI 1166
            + E P   +   FG+ V  + I   +FG+IF +G+LGN LVI V+ R+  G  R++TN+ I +L+ ADL +++FCIP   ++Y    W+   F+C    Y   +++  S++TL  MS DRY+AIVH   S + R    +L  V   W   I +  P   H R+ +       +NQT    +C  +   KL      +  ++  Y               LLPL +I   Y  +L  + ++L N        S KK  + V+ V++ FG+SWLP H+V L       P   A   F + A+ +AY NS +NPI+YAFLSENFR A+K+   C +
Sbjct:   15 DPEPPAPESRPLFGIGV-ENFITLVVFGLIFAMGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASPVAYHQRLFHR-----DSNQT----FCWEQWPNKLHKKAYVVCTFVFGY---------------LLPLLLICFCYAKVLNHLHKKLKNMSKK-SEASKKKTAQTVLVVVVVFGISWLPHHVVHLWAEFGAFPLTPASFFFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHV 321
[Close]
BLAST of GCR317 vs. UniProt/SwissProt
Match: sp|O88854|GALR2_MOUSE (Galanin receptor type 2 OS=Mus musculus OX=10090 GN=Galr2 PE=2 SV=2)

HSP 1 Score: 145.976 bits (367), Expect = 2.367e-38
Identity = 98/320 (30.63%), Postives = 170/320 (53.12%), Query Frame = 3 
Query:  198 KSSNSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMD--GYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANIT-RSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKK 1148
             SS     G Q   +++VP  F +IF+VG +GN LV+AV++R G   ++TN+ I +L  ADL FI+ C+P   +IY    W++ + LC    +L +LT++ S +TL  +S DRYLAI +P+ S   RT   +L A+ + W   ++ + P+L      Y    +LAN       +   ++      AMD   ++  Y               LLP+ ++ + Y   L+ + + ++   + + + R+ +KVTR++V V + F + W+P H + L       P   A  A  ++++ ++Y NS +NPI+YA +S++FR  F+K
Sbjct:   11 DSSQEGGGGWQP-EAVLVPLFFALIFLVGAVGNALVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLS-----YYSQSQLANLTVCHPAWSAPRR-----RAMDLCTFVFSY---------------LLPVLVLSLTYARTLHYLWRTVDPVAAGSGSQRAKRKVTRMIVIVAVLFCLCWMPHHALILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRK 304
[Close]
BLAST of GCR317 vs. TrEMBL
Match: A0A193KUG3 (GCR317 OS=Schmidtea mediterranea OX=79327 GN=gcr317 PE=2 SV=1)

HSP 1 Score: 738.799 bits (1906), Expect = 0.000e+0
Identity = 398/400 (99.50%), Postives = 400/400 (100.00%), Query Frame = 3 
Query:   90 MEVMGFVLITFMLVQATGNAQKIFNFSEISINVEFPKSSNSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKISPCHLXXXXXXXXXXXXXXQNQELITKCEMETCLPLINSKD 1289
            MEVMGFVLITFMLVQATGNAQKIFNFSEISINVEFPKSSNSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLT+SIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKALFNHYFTFFLFGFLLPLSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKISPCHLSSSSEAAANGSNKNQNQE+ITKCEMETCLPLINSKD
Sbjct:    1 MEVMGFVLITFMLVQATGNAQKIFNFSEISINVEFPKSSNSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTISIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKALFNHYFTFFLFGFLLPLSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKISPCHLSSSSEAAANGSNKNQNQEIITKCEMETCLPLINSKD 400
[Close]
BLAST of GCR317 vs. TrEMBL
Match: A0A193KUH5 (GCR032 OS=Schmidtea mediterranea OX=79327 GN=gcr032 PE=2 SV=1)

HSP 1 Score: 263.848 bits (673), Expect = 1.124e-80
Identity = 146/313 (46.65%), Postives = 206/313 (65.81%), Query Frame = 3 
Query:  231 VLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRI--SQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCK 1163
            ++T ++ P++FG+I V G  GN LVI V+  N  +RN TNILI+SLA AD+TFI FC+PLT +I+I +GW   +  C IYQ+ T+LT Y SVYTLVLMS DRYLA+VHPI S+  RT    L  V  +W+  ++ N P L +S V Y  P  +  N T K++YC     V YNE + GY+++ +    +   F +F +LLPLS I++LY  L++++  +      QS    +S K+VTR+VV V++ F + W+P+ IVF+IQ    +P N AF+AFH+ A+++AY NSM+NPILYAF S NFR AFK  L C+
Sbjct:    9 IITEMVAPSIFGVIVVFGFFGNLLVILVVSINKQLRNGTNILIASLAIADITFITFCVPLTATIFIKKGWFLGSIACKIYQFFTYLTAYMSVYTLVLMSVDRYLAVVHPIASIPIRTEKNVLKIVLSTWVIFMLCNCPLLFNSGVAYP-PTSI--NDT-KDFYCTYMPTVRYNETLMGYLENGQFGRVYILLFSIFAYLLPLSAIILLYTCLIWKLLFNSESRISQSDKALQSKKRVTRMVVIVVVIFALCWMPIQIVFIIQFLGSEPDNAAFKAFHVFASALAYSNSMMNPILYAFFSNNFRVAFKSVLFCQ 317
[Close]
BLAST of GCR317 vs. TrEMBL
Match: A0A193KUR9 (GCR304 OS=Schmidtea mediterranea OX=79327 GN=gcr304 PE=2 SV=1)

HSP 1 Score: 261.922 bits (668), Expect = 4.147e-79
Identity = 145/317 (45.74%), Postives = 201/317 (63.41%), Query Frame = 3 
Query:  225 MQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRI----SQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCK 1163
            M++LTS+ VP LFG+I VVG +GN LVI VII N  MRN+TNILI SLA ADL FI+FC+P T  +Y+  GW     LC IYQY+T++T YCSVYTLVLMS DRYLA+VHPI S+  R    ++ AV   W   ++ NLP LI+S ++     ++ +       YC  K  + +N     Y DD      +Y  FF+  +L P+ +I +LYG L+YR+    S ++++   A +T+  K+VT++V+ VI+ F + W P+  +F+IQ    DP    FR  H+++N +AY NSM+NP LYAFLSENFR AF   L C+
Sbjct:   32 MKILTSVAVPILFGLIMVVGFVGNLLVIVVIIANIQMRNTTNILIISLAVADLLFIIFCVPFTAVMYVTGGWPLGRVLCQIYQYMTYITAYCSVYTLVLMSIDRYLAVVHPIRSMTLRNSRNTIIAVGTVWSLFLVSNLPLLINSDIIEGPRDEITDCLVD---YCTYKPFMKWNSTKKRYEDDKVFGKIYYTLFFVMFYLWPVIIISVLYGFLIYRLLCGRSSKISHSNDAMVTK--KRVTKMVIVVIVIFTLCWAPIQTIFIIQLYGKDPGGNLFRTIHVISNCLAYSNSMVNPFLYAFLSENFRRAFANLLCCR 343
[Close]
BLAST of GCR317 vs. TrEMBL
Match: A0A193KUP0 (GCR064 OS=Schmidtea mediterranea OX=79327 GN=gcr064 PE=2 SV=1)

HSP 1 Score: 250.751 bits (639), Expect = 3.365e-75
Identity = 152/316 (48.10%), Postives = 199/316 (62.97%), Query Frame = 3 
Query:  231 VLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKN---YYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQ--QSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCK 1163
            VLTSI+VP LFG+I ++G  GN +V+ VII N  MRNSTNILI+SLA ADLTFI FCIP T  IY+ QGW      C IYQ+L ++T YCSVYTLVLM  DR+LA+VHPI+S   R+   +   V + WI     NLP L++S V+          +++ N   YYC    LV +N+  D Y+ D K     + +FF+F + LPL MI +LYG LL R+     ++  QS    +S K+VT +VV VI+AF   WLP+  VFL+Q    D     FR  H+ +N +AY NSM+NPILYAFLSENFR +F+  L C+
Sbjct:   24 VLTSIVVPILFGLIIILGAFGNIMVLVVIIFNKKMRNSTNILIASLAIADLTFIAFCIPFTGVIYVKQGWPLGESFCRIYQFLIYVTAYCSVYTLVLMCFDRFLAVVHPISSSLVRSDRNTFLGVVVMWILFTGTNLPLLLNSGVIK------GRKESKVNCVVYYCSYLPLVRWNDTTDQYVVDIKFGKRFFTSFFIFAYFLPLLMISLLYGKLLCRLLHGRTSKMAQSNEALKSKKRVTIMVVIVIVAFAACWLPIQSVFLLQIYEFDVGGPLFRTIHIFSNCLAYANSMVNPILYAFLSENFRRSFRDLLCCQ 333
[Close]
BLAST of GCR317 vs. TrEMBL
Match: A0A5J4NUA6 (Allatostatin receptor OS=Paragonimus westermani OX=34504 GN=DEA37_0000272 PE=3 SV=1)

HSP 1 Score: 250.366 bits (638), Expect = 3.712e-75
Identity = 150/326 (46.01%), Postives = 205/326 (62.88%), Query Frame = 3 
Query:  201 SSNSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQR--LNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKISP 1172
            SS      + +    + P LF +IF+VGL+GN LVI V++ N  MRN+TNILI +LA ADL FIV CIP T  +Y   GW   + LC ++ Y ++++VYCSVYTL+LMS DR+LA+V+PI  V+ RT++ S+ AV   WI L++ NLP  + SRV+     + +N+    N YC  K LV   E  +   D+ +     +  FFLFG+L+PL +I  LY  L+YR+  R  +  +QSA   RS K+VT LV++V+I FG+SWLPLH+VFL Q    DP+   FR   +V N +AYGNS +NPI YAFLS NFR AF   L  +  P
Sbjct:   21 SSAEELNHLTIFARYVTPVLFSVIFIVGLVGNLLVIVVVLANAQMRNTTNILIFALAIADLAFIVLCIPSTTIVYFVGGWPLGDILCHMFYYCSFVSVYCSVYTLLLMSLDRFLAVVYPIQCVHIRTQSNSVKAVLCVWIVLLLANLPLFMLSRVVQG-SAEGSNSSCVTN-YCTYKYLVVEVENSNLVTDNKEFGKVFFTLFFLFGYLIPLVIICALYICLIYRLRCRKIVQLKQSAESRRSQKRVTTLVITVVIIFGLSWLPLHVVFLFQYYSEDPNTTLFRVIQIVCNCLAYGNSCVNPIFYAFLSINFRKAFIDLLHGRRQP 344
[Close]
BLAST of GCR317 vs. Ensembl Cavefish
Match: ENSAMXT00000006013.2 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000032.1:4195125:4261560:1 gene:ENSAMXG00000005876.2 transcript:ENSAMXT00000006013.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 172.94 bits (437), Expect = 1.304e-49
Identity = 114/327 (34.86%), Postives = 178/327 (54.43%), Query Frame = 3 
Query:  201 SSNSSAFGMQVLTS--IIVPALFGIIFVVGLLGNGLVIAVI--IRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGD-PSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKI 1166
            S NS+  G   L+   ++VP +FG IF +G++GN LV+ V+  I++G  R++TNI I +L+ ADL+F++FC+P   +IY    WI+  FLC    Y   +T+  S++TLV MS DRY+A+V    S   R R  +L  V+I W+  ++  +P   H        V   +     + +C     +     + GY+                   LPL +I   Y  +LY + +++ N  S    RS +K  + V+ V+ AF + W+P HI+  +   +GD P N A  AF +V++ +AYGNS +NPILYAFLSENFR A ++  TC++
Sbjct:   19 SHNSNHTGKDPLSPEVVLVPVVFGCIFFLGIVGNALVMVVLGRIKSGRSRSTTNIFILNLSIADLSFLLFCVPFQATIYSLPEWIFGAFLCKSVHYFVTVTMLVSIFTLVAMSVDRYVAVVLSKKSPCIRNRRNALLGVWIIWLLSLVFAVPVAQHQ-------VVTDHPDAPNSSFCWE---IWVTILVIGYL-------------------LPLVLITCCYAKVLYHLHKKIKN-MSKKSERSKRKTAQTVLLVVAAFLLCWMPHHII-AMWVEFGDFPLNDASFAFRIVSHCLAYGNSCVNPILYAFLSENFRKACRQVFTCRL 314
[Close]
BLAST of GCR317 vs. Ensembl Cavefish
Match: galr2b (galanin receptor type 2-like [Source:NCBI gene;Acc:103040671])

HSP 1 Score: 162.925 bits (411), Expect = 1.556e-45
Identity = 103/317 (32.49%), Postives = 173/317 (54.57%), Query Frame = 3 
Query:  240 SIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMR-NSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQS-----ANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGD-PSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKIS 1169
            S+IV  +F +IF++G +GN LV+AV++R+G +  N+TN+ I +L+ AD  FI+FC+P   +IY  +GW++ +F+C +  +   LT+Y S +TL  +S DRYLAI +P+ S   RT   ++ A+ I W   +I   P+L +    Y +     +N     +   N+K+++    + GY+                       + V++  L   R  + L          +   R+ +KVT++++ V + F + WLP H+V L    YGD P N    AF ++++ MAY NS +NPI+YA +S++FR  FKK  +C +S
Sbjct:   26 SVIVSVVFSLIFLLGTVGNSLVLAVLLRSGQVGYNTTNLFILNLSVADFFFIIFCVPFQATIYSLEGWVFGSFMCKVVHFFINLTMYASSFTLAAVSVDRYLAIRYPLRSRELRTPCNAVVAMVIIWGLSLIFAGPYLSY----YDLIDFENSNVCVPGWEEHNRKVLDTCTFVFGYV-----------------------IPVLIVSLSYTRTIKYLWTAVDPLDVMSESKRAKRKVTKMIIIVTVLFCICWLPYHVVILCY-LYGDFPFNQTTYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFKKVFSCILS 314
[Close]
BLAST of GCR317 vs. Ensembl Cavefish
Match: GALR1 (galanin receptor type 1 [Source:NCBI gene;Acc:103047815])

HSP 1 Score: 150.599 bits (379), Expect = 2.534e-41
Identity = 103/318 (32.39%), Postives = 166/318 (52.20%), Query Frame = 3 
Query:  243 IIVPALFGIIFVVGLLGNGLVIAVIIRN--GHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYC-------GNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKIS 1169
            +I   +F +IF +G+LGN +VI V+ R+  G  R++TNI I +L+ ADL++++FC+P   ++Y+   W+   F C    Y   +++  S++TL  MS DRY+AIV   +S + R    +L AV   W+  + +  P   H R+     ++  +N T    YC        ++K+      + GY+                   LPL +I   Y  +L  + ++L N  S     S +K  + V+ V++ F +SWLP H+V L       P N A   F + A+ +AY NS +NPI+YAFLSENFR A+K+   C+I+
Sbjct:   23 VITLLVFALIFALGVLGNAVVITVLARSRPGRARSTTNIFILNLSVADLSYLLFCVPFQATVYVLPTWVLGAFACKFVHYFFTVSMLVSIFTLSAMSVDRYVAIVRARSSSSVRVARNALLAVVAIWLLSLAMAAPVAYHQRI-----IEREDNAT----YCWELWPQAHHRKIYVVCTFVFGYV-------------------LPLLLISFCYARVLNHLRKKLKN-MSKKSEASKRKTAQTVLVVVVVFCLSWLPHHVVHLWVEFGSFPLNQASFIFRVAAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCQIT 311
[Close]
BLAST of GCR317 vs. Ensembl Cavefish
Match: galr1a (galanin receptor type 1 [Source:NCBI gene;Acc:103037936])

HSP 1 Score: 147.902 bits (372), Expect = 2.977e-40
Identity = 111/349 (31.81%), Postives = 178/349 (51.00%), Query Frame = 3 
Query:  162 NFSEISINVEFPKSSNSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIR--NGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLY-----TIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKIS---PCH 1178
            + SE + ++E P        G+  L ++++   FG+IF +G+LGN LVI V+ R  +G  R++TN+ I +L+ ADL++++FCIP   ++Y+   WI+  F+C    Y   +++  S++TL  MS DRY+AIVH   S + R    +L  V + W   + +  P   H  ++      T   ++  N TR+  Y     +  Y                          LLPL +I   Y  +L  + ++L N    +   S KK  + V+ V++ F +SWLP H+V L       P N A   F + A+ +AY NS +NPI+YAFLSENFR A+K+   C+++   P H
Sbjct:    8 DISERAADLEAP------GLGVDNLVTLLI---FGLIFTLGVLGNSLVITVLARRKSGQQRSTTNVFILNLSIADLSYLLFCIPFQSTVYMMPSWIFGEFICKFVHYFFTVSMLVSIFTLSAMSVDRYVAIVHCRKSSSIRVVRHALAGVAVIWALSLAMAAPVAHHQSIVESKDNSTFCWEVWPNHTRRKIYVVFTFIFGY--------------------------LLPLILISFCYAKVLNHLHKKLRNVSKKSEA-SKKKTAQTVLVVVVVFCLSWLPHHVVHLWVEFGSFPLNQASFLFRVAAHCLAYSNSSVNPIIYAFLSENFRQAYKQVFRCQVASECPVH 320
[Close]
BLAST of GCR317 vs. Ensembl Cavefish
Match: ENSAMXT00000053361.1 (G-protein coupled receptor 54 [Source:NCBI gene;Acc:103023540])

HSP 1 Score: 140.584 bits (353), Expect = 2.587e-37
Identity = 104/349 (29.80%), Postives = 166/349 (47.56%), Query Frame = 3 
Query:  144 NAQKIFNFSEISINVEFPKSS-NSSAFGMQ---VLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRL-----NNQQ----SANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGD-PSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKK 1148
            + +K +N SE+ +N     SS      G Q   +  + +VP  F +I +VGL+GN LVI VI ++  MR +TN  I++LA  D+ F+V C+P T ++Y   GWI+ +F+C    +L  +TV  +  TL  MS DR    V+P+ S+  RT   ++      WI   I++ P  ++ R+                Y+ G ++       M+ +           + F     L  L+ I   Y  +L R+         +N Q    S        K++++VV +++ F V W P+ I  L QS Y +   N A       AN M+Y NS INPI+Y F+  +FR +F+K
Sbjct:    3 SCKKSWNVSEMLLNGSAGNSSLEDVEDGGQHPFLTDAWLVPLFFSLIMLVGLIGNSLVIYVISKHRQMRTATNFYIANLAATDIIFLVCCVPFTATLYPLPGWIFGDFMCKFVAFLQQVTVQATCITLTAMSGDRCYVTVYPLKSLRHRTPRVAMIVSICIWIGSFILSTPIFLYQRL-------------EDGYWYGPRQY-----CMERFPSKAHERAFILYQFIAVYLLPVLT-ISFCYSFMLKRVGHPTVEPVDSNHQVHLLSERTISIRSKISKMVVVIVLLFTVCWGPIQIFALFQSFYPNFKVNYATYKIKTWANCMSYANSSINPIVYGFMGASFRKSFRK 332
[Close]
BLAST of GCR317 vs. Ensembl Sea Lamprey
Match: galr1b (galanin receptor 1b [Source:ZFIN;Acc:ZDB-GENE-140624-1])

HSP 1 Score: 149.828 bits (377), Expect = 1.275e-41
Identity = 105/315 (33.33%), Postives = 168/315 (53.33%), Query Frame = 3 
Query:  237 TSIIVPALFGIIFVVGLLGNGLVIAVII-RNGH--MRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDG-YIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGD-PSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKI 1166
            T IIVPA+FG+IF++G+LGN LV+ V++ R      RN+TN  I +L+ ADLTF++ C+P   +IY+   W++  FLC    Y   + +  S++TL  MS +RY+A+VH   S   RT   +L  V + W   ++  +P    +R+L    V   N      ++C   +       + G +I  Y               LLPL +I   Y  +L  + +++ N    +     K    ++V V+  F +SWLP H++ +    YG  P   A  AF +V++ ++YGNS  NPI+YAFLSENFR A+++  +C++
Sbjct:   28 TGIIVPAVFGVIFLLGVLGNTLVLVVLLCRKSRRVQRNTTNTFILNLSVADLTFLMVCVPFQSTIYVLPTWVFGAFLCKAVHYFVTVFMLVSIFTLAAMSVERYIAVVHSHRSPVLRTTRNALAGVAVIWALSVVAAIP-CAQNRML----VDGVNYSHPGQFFCWEAEASKRRAYITGIFIFGY---------------LLPLLLISCCYISVLTHLQRKVRNISKKSQRSKKKTAQTVLV-VVAVFCISWLPHHVIHM-WVLYGSFPLTSASFAFRIVSHCLSYGNSCANPIIYAFLSENFRKAYRQVFSCQL 320
[Close]
BLAST of GCR317 vs. Ensembl Sea Lamprey
Match: galr2a (galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-130603-37])

HSP 1 Score: 142.124 bits (357), Expect = 5.748e-39
Identity = 92/307 (29.97%), Postives = 163/307 (53.09%), Query Frame = 3 
Query:  240 SIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNS---TNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNN-QQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKK 1148
            S+ VP +F +IF++G  GN LVI V++ +G   +S   TNI I +L+ ADL FI+FC+P   +IY   GWI+ +FLC    ++ +LT++ S +TL  +S DRYLAI +P+ S   RT  ++   +   W   ++   P+L + + +    + +      K      +KL++    + GY+                   +P+S++ + Y   L  +   ++  ++ +   R+ +KVT +++ V   F   WLP H++ L       P   A  AF ++++ M+Y NS +NP++YA +S++FR  F+K
Sbjct:   25 SVTVPVVFLLIFLLGAFGNSLVIIVLLCSGQRGSSNTTTNIFILNLSVADLCFILFCVPFQATIYTLDGWIFGSFLCKAVHFIIFLTMFASSFTLAAVSVDRYLAIRYPLRSRELRTPRKAAAVIAAIWGLALVFAGPYLSYYQAVTFQNMSMCMPVWAKE----PRKLMDMVTFVCGYL-------------------VPVSVLGLAYAFTLKYLWTAVDPLEEMSESKRAKRKVTTMILIVAGLFCACWLPHHVLILYFWFGHFPLTHATYAFRLLSHCMSYANSCLNPLVYALVSKHFRKGFRK 308
[Close]
BLAST of GCR317 vs. Ensembl Sea Lamprey
Match: galr1a (galanin receptor 1a [Source:ZFIN;Acc:ZDB-GENE-060503-290])

HSP 1 Score: 141.739 bits (356), Expect = 8.774e-39
Identity = 101/338 (29.88%), Postives = 169/338 (50.00%), Query Frame = 3 
Query:  171 EISINVEFPKSSNSSAFGMQ--VLTSIIVPALFGIIFVVGLLGNGLVIAVIIR--NGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSV----IIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTC 1160
            +++IN  +P        GMQ  ++++I+VP +F +IF++G++GN LVI V++R   G   + TN+ + +L+ ADLTF+ FC+P   + Y    W++  FLC    Y+   ++  S++TLV MS DRY+AIVH   +   R+  R+L AV   W+  +++ +P                    R +Y+     +V Y E  +   + +           +   L  L  +V++        S     + SA +    K+  R         ++ F VSWLP H++ L       P   A  AF +VA+ ++YGNS +NP +Y FLS+NFR A+++ L C
Sbjct:   22 DLAINGSYP--------GMQEHIVSAIVVPVIFFVIFLLGIVGNSLVILVLVRIKFGKSHSITNVFVLTLSVADLTFLFFCVPSEATYYFLPDWVFGAFLCKGVPYVFTASMLVSIFTLVAMSVDRYIAIVHARRAAAVRSVRRALGAVSALWLLSLVLAVP--------------------RAHYH----TIVVYKEHGNFCWEVWSHKNLKSTYRAVIFSLGYLLPLVLISACYARVGSTVFTCRDSAELVDETKQSVRQTAKTVLVLVVVFLVSWLPHHVILLWVEFGSFPLTNASFAFRIVAHCLSYGNSCVNPFIYGFLSQNFREAYRQLLRC 327
[Close]
BLAST of GCR317 vs. Ensembl Sea Lamprey
Match: kiss1rb (KISS1 receptor b [Source:ZFIN;Acc:ZDB-GENE-060526-54])

HSP 1 Score: 136.346 bits (342), Expect = 1.372e-36
Identity = 102/321 (31.78%), Postives = 161/321 (50.16%), Query Frame = 3 
Query:  246 IVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNY----YCGNK-KLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANI-----TRSNK----KVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMV--ANSMAYGNSMINPILYAFLSENFRTAFKKFLTC 1160
            +VP LF +I +VGL+GN LVI VI +N  MR  TN  I +LA  D+ F+V C+P T ++Y    W++ +F+C    YL  +TV  +  TL  MS DR    V+PI S+  RT   +       WI  ++++LP  ++ +             T++ Y    YC +    V +  A   Y              F+  ++LPL  I + Y +++ +I +     Q  N+     T  N+    KVTR+VV V++ F + W P+ +  L QS Y   + +++  + +   AN M+Y NS INP +Y F+ ++FR  FKK   C
Sbjct:   38 LVPLLFALIMLVGLVGNSLVIFVITKNRQMRTVTNFFIVNLAGTDIIFLVCCVPFTATLYPLPSWVFGDFMCKFVNYLQQVTVQATCMTLTAMSVDRCYVTVYPIRSLQHRTPCLAACISIGIWIGSLVMSLPMALYHK-----------TDTKEWYGPKTYCFDAFPSVPHEHAFVLY-------------SFVLVYMLPLVTISVCYSIMIKKIGRPAVEPQDDNVQLQMLTERNEATRAKVTRMVVVVVLVFMLCWGPIQLFILFQSFYPHFA-ISYTTYKLKTWANCMSYANSSINPFVYCFMGDSFRKTFKKAFPC 333
[Close]
BLAST of GCR317 vs. Ensembl Sea Lamprey
Match: prlh2r (prolactin releasing hormone 2 receptor [Source:ZFIN;Acc:ZDB-GENE-120411-41])

HSP 1 Score: 117.857 bits (294), Expect = 4.372e-30
Identity = 100/339 (29.50%), Postives = 160/339 (47.20%), Query Frame = 3 
Query:  222 GMQVLTSI--IVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLS-IYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYIS---WIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCG--NKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLL-------YRISQRLNN--------QQSANITRSNKKVT-RLVVSVIIAFGVSWLPLHIV-FLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCK 1163
            G+Q++ ++   V   +  + VVG+LGN L++ VI R   M N TN+LI +LAF+DL     C+PLTL+ ++  +GW++ +F+C     +  ++VY SV+TL +++ DRY+  V+P+     R R    T  Y+    W+    +  P L H+                  YYC    +++    E   G   +  A                 S +V+ YGL L       ++IS +L N        Q  A + R+ ++ T RL+V V+ AF V WLPLHI  FL            F    ++ +  A  ++  NP +YA+L + FR+  KK  T K
Sbjct:   13 GVQLIRTLKPFVVLFYTAVVVVGVLGNFLLVYVICRVKKMHNVTNLLIGNLAFSDLLMCAMCVPLTLAYVFDARGWVFGSFMCYFVFLMQPVSVYVSVFTLTVIAVDRYIVTVYPL-----RRRITIPTCGYLLAAIWVTACALAAPALAHT------------------YYCEFPEQRMTICEEFWIGTERERLA--------------YAYSTLVLTYGLPLLVISLSYFKISVKLKNRVVPGTVTQNQAEMDRARRRKTFRLLVLVVTAFSVCWLPLHIFNFLRDVDIRLIDKYYFNLVQLLCHWFAMSSACYNPFIYAWLHDRFRSELKKMFTVK 314
[Close]
BLAST of GCR317 vs. Ensembl Nematostella
Match: EDO49911 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RF82])

HSP 1 Score: 113.62 bits (283), Expect = 1.633e-28
Identity = 94/310 (30.32%), Postives = 154/310 (49.68%), Query Frame = 3 
Query:  267 IIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWN------NFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQ-----SANITRSNKKVTRLVVSVIIAFGVSWLPLHI----VFLIQSTY--GDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFK 1145
            ++ V+ L+GN LV+ VI     MR  TN  I+++AFADL   VF +  TL   I +   W+        LC   Q+   ++V CSV+++  +S DR+ AI  P+         R +T     +I  +I     LI S ++Y + ++            G+ + VN  E      DDY +   +    F+  + LPL++I  LY ++++R+ +R    Q      +N  R+NKKV +++++V+  F + WLPL++    VFL  S +  G P ++ F     +   + + NS INP LY   +ENFR  FK
Sbjct:    8 LVVVLSLIGNALVVWVIRSAYRMRTVTNYFITNVAFADLLTTVFNMMPTLFWIIERKDPWSVGGTLGEILCKTLQFFQCVSVACSVFSMAAISMDRFFAIFRPL--------KRIITFKLAKFIIALIWASSCLISSPLIYALKLE------------GDGEDVNCVEVWAPLFDDYTSPMVYTIALFVLFYALPLTIIAALYAVIMFRLWRRQTPGQNSTSNQSNKERTNKKVLKMLITVVAVFALCWLPLYVRMFLVFLQPSNFPCGLPYHLDF-----ITLFLGHANSSINPYLYVVFNENFRKGFK 292
[Close]
BLAST of GCR317 vs. Ensembl Nematostella
Match: EDO36377 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIX0])

HSP 1 Score: 113.235 bits (282), Expect = 1.125e-27
Identity = 96/310 (30.97%), Postives = 151/310 (48.71%), Query Frame = 3 
Query:  267 IIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLS-IYIYQGWI---WNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILY---GLLLYRISQRLNNQQS----ANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSN--VAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLT 1157
            +IFVV L+GN +V+ ++    HMRN+TNILI+++A ADL +I F IP  +   YI   W    + +FLC         +V CSV+TLV +S DR  AI+ P+  +   TR      +   W A I    P  + ++V             +   Y  N+      ++   YI  Y           +  +++PL++I+I+Y   GL L+  S++   Q+S      I  S ++ T ++++V++ F V W P  I  L+   Y D  N  + FR    +     + NS INPILY   SEN+R  F++  T
Sbjct:   33 LIFVVALVGNSIVVYIVCSCNHMRNTTNILIANMAVADL-WITFDIPYVIKWFYITDTWFGGGFGDFLCKFCHSAQAGSVACSVFTLVCISLDRSFAIIFPMKVI--LTRKIVKFMILGIWAATIAFTTPIFLITKV-----------HLKNGVYVCNELWEESGQSERHYIAVYT----------ITTYIIPLALILIMYIFTGLKLW--SRKPPGQRSLQAHKKIQSSTRRATIMLITVVVVFAVCWFPFQIRELLSVFYEDNINNMIPFRVMLFLP-WFGFANSAINPILYVLFSENYRREFRRTFT 315
[Close]
BLAST of GCR317 vs. Ensembl Nematostella
Match: EDO44418 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVN5])

HSP 1 Score: 104.76 bits (260), Expect = 1.532e-25
Identity = 84/297 (28.28%), Postives = 143/297 (48.15%), Query Frame = 3 
Query:  261 FGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYI--DDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFK 1145
            +  I  + L+GN +VI  + RN HM++ TN+ I++LA +DL      +P  ++      W++   LC +  YL  ++V  SV TL+ ++ DR++AI+ P     +R R    TA     I ++I +L   I + ++Y    K+ NNQ  +          ++  A D      DY  +            +  L  I++       RI + + +  S N   S KKV +++++VI+ F  SWLPLH+   I        + +  A + V+  + +GNS  NP LYA  ++N+R  FK
Sbjct:    3 YATIIALSLVGNTVVIFTVCRNRHMKSVTNLFIANLAASDLLITFLGMPHQITELYTTEWMFGTVLCKLVVYLQSVSVGSSVLTLLAITKDRFVAIIFP-----FRPRMSFKTA---KTIIMLIWSLSLGIMAPLIYA--TKVHNNQCTE----------DWTPAFDAKTAPRDYTVVLFVMLYAVPMLTMAVLYAIIVRKLWRRRRIGEVIPSASSKN-EVSRKKVIKMLITVIMLFTFSWLPLHVFSFISFFAPFCPDTSNTALYFVSLFLGHGNSAANPYLYALFNQNYRDGFK 278
[Close]
BLAST of GCR317 vs. Ensembl Nematostella
Match: EDO50021 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RF31])

HSP 1 Score: 104.375 bits (259), Expect = 1.869e-25
Identity = 92/292 (31.51%), Postives = 154/292 (52.74%), Query Frame = 3 
Query:  270 IFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQG-WIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAF 1142
            I ++G LGN L++ +  R   MRN TN  I++LA AD T  V  IP++L +Y   G W + ++LC    YL  +TV  SV TLV +++DR++ IV P T   +R           +WI ++ I   +L+ + V +  PV L +  TR+    G+   +N    ++ +         +    FL  FLLP++ I ++Y  ++Y++ + L+  Q   + R++KK+ R++V VI+ F V W+P H+ FL        +  A  A  + +  + Y NS +NPI+Y   + N+R  F
Sbjct:    6 ICIIGALGN-LLVMLATRKRRMRNVTNQFIANLALADFTVCVITIPISL-VYTNLGHWPFRSWLCKTMPYLQGITVSASVGTLVAIASDRFIVIVFP-TKRKFRISR--------TWITVVAI---WLLSAAVAF--PVHLYSEVTRE---MGDG--LNVTSCIEVW-PSQDGRKTYALLLFLVLFLLPMTAISLMYAAIIYKL-RTLHPTQEVTM-RTHKKLVRMLVVVIVTFAVCWIPYHVTFLYLDKSDYITTEAMNAMVLFSQWLMYTNSCLNPIIYILYNANYRREF 273
[Close]
BLAST of GCR317 vs. Ensembl Nematostella
Match: EDO39181 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAU0])

HSP 1 Score: 103.219 bits (256), Expect = 6.889e-25
Identity = 81/310 (26.13%), Postives = 155/310 (50.00%), Query Frame = 3 
Query:  261 FGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQ-------GWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTA-VYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLL---LYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDP--------SNVAFRAFHMVANSMAYGNSMINPILYAFLSENFR 1133
            + ++F+V   GN L I+V++ N H++ +TN+ I +LA +DL   + C+P ++   +           I+  FLC ++Q+L  +++  S+ T+  +  DR+LAIV+P  ++     ++ + A V+ + IA I         S +LY +    A N++    YC         E  +   D +KA  ++    F+  +  PL +I +LY  L   L++ S+  ++++ A   + NK V +++V++I+ F + WLP+H+V  +     DP        + V F  +      + + +S  NP +Y   +E FR
Sbjct:    7 YNVVFIVAFFGNILAISVVLSNVHLKTTTNVFILNLAISDLLIAIVCMPSSMHSIVAHSRQTSEVSGIFGAFLCKLHQFLQGISITSSILTVECIGCDRFLAIVYPFKNIITLPISKIIVALVWFTSIACI---------SPLLYALKFHDAGNES----YC--------YEKWEPLFDTHKASVHYTLFLFVVQYAAPLLLITVLYSTLIKDLWQSSRTHSDRKRAY--KENKAVLKMLVTIILTFAIFWLPMHVVMFVSIYTTDPVINACGPKAAVVFLGWF-----LGHAHSACNPTIYFTFNEKFR 288
[Close]
BLAST of GCR317 vs. Ensembl Medaka
Match: galr2a (galanin receptor type 2 [Source:NCBI gene;Acc:101155603])

HSP 1 Score: 163.696 bits (413), Expect = 8.482e-46
Identity = 100/311 (32.15%), Postives = 174/311 (55.95%), Query Frame = 3 
Query:  237 TSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMR-NSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTR-KNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGD-PSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTC 1160
            TS+IV  +F +IF++G +GN LV+AV++R+G +  N+TN+ I +L+ AD  FI+FC+P   +IY  +GW++ +F+C +  +   LT+Y S +TL  +S DRYLAI +P+ S   RT   ++ A+ + W   ++   P+L +  +     +  AN+      +   ++K+++    + GY+                  +L +S+        L+     L+    +   R+ +KVT++++ V + F + WLP H+V L    YGD P N    AF ++++ MAY NS +NPI+YA +S++FR  FKK  +C
Sbjct:   25 TSVIVSVVFSLIFLLGTIGNSLVLAVLLRSGQVGYNTTNLFILNLSVADFFFIIFCVPFQATIYSLEGWVFGSFMCKVVHFFINLTMYASSFTLAAVSVDRYLAIRYPLRSRELRTPCNAVVAMVVIWGLSLVFAGPYLSYYDL-----IDYANSTVCIPGWEEQDRKVLDTCTFLFGYV----------------IPVLIVSLSYTRTIKYLWTAVDPLDGMSESK--RAKRKVTKMIIIVTVLFCICWLPYHVVILCY-LYGDFPFNQTTYAFRLLSHCMAYANSCVNPIVYALVSKHFRKGFKKVFSC 311
[Close]
BLAST of GCR317 vs. Ensembl Medaka
Match: ENSORLT00000036456.1 (galanin receptor type 1 [Source:NCBI gene;Acc:101175549])

HSP 1 Score: 155.606 bits (392), Expect = 3.270e-43
Identity = 99/307 (32.25%), Postives = 166/307 (54.07%), Query Frame = 3 
Query:  237 TSIIVPALFGIIFVVGLLGNGLVIAVI--IRN-GHMRN--STNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAF 1142
            +++IVP +FG+ F VG++GN LV+ VI  ++N G  R+   TNI I +L+ ADL+F++FC+P   +IY    W++  FLC    Y   +T   S++TLV MS DRY+ +V P  S   R+R  +L  + + W+  ++ ++P  +H +V+   P    ++   +N+   +++              YK                   +I   Y  +L+ + +++ N  S    RS +K  + V+ V+ AF + W+P HI+ +       P N A  AF +V++ ++YG+S +NPILYAFLS+NFR AF
Sbjct:   17 SAVIVPVVFGLFFAVGVVGNCLVLVVIGKVKNRGGARSLSPTNIFIVNLSVADLSFLLFCVPFEATIYSLPEWVFGGFLCKFGHYFFTVTKLVSIFTLVAMSVDRYVVVVRPKKSACARSRMSALVGLCVIWMGSLVCSVPVALH-QVVTNHPSAPNSSFCWENWRGPSRQF-------------YKVSILLLGYLLPL------LLICCCYTRILWHLHKKMKNM-SRKSQRSKQKTAQTVLLVVTAFTICWMPHHIIAMWVEFGTFPLNDASLAFRIVSHCLSYGHSCVNPILYAFLSKNFRRAF 302
[Close]
BLAST of GCR317 vs. Ensembl Medaka
Match: ENSORLT00000000456.2 (galanin receptor type 1 [Source:NCBI gene;Acc:101175549])

HSP 1 Score: 155.221 bits (391), Expect = 4.198e-43
Identity = 99/306 (32.35%), Postives = 165/306 (53.92%), Query Frame = 3 
Query:  240 SIIVPALFGIIFVVGLLGNGLVIAVI--IRN-GHMRN--STNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAF 1142
            ++IVP +FG+ F VG++GN LV+ VI  ++N G  R+   TNI I +L+ ADL+F++FC+P   +IY    W++  FLC    Y   +T   S++TLV MS DRY+ +V P  S   R+R  +L  + + W+  ++ ++P  +H +V+   P    ++   +N+   +++              YK                   +I   Y  +L+ + +++ N  S    RS +K  + V+ V+ AF + W+P HI+ +       P N A  AF +V++ ++YG+S +NPILYAFLS+NFR AF
Sbjct:    8 AVIVPVVFGLFFAVGVVGNCLVLVVIGKVKNRGGARSLSPTNIFIVNLSVADLSFLLFCVPFEATIYSLPEWVFGGFLCKFGHYFFTVTKLVSIFTLVAMSVDRYVVVVRPKKSACARSRMSALVGLCVIWMGSLVCSVPVALH-QVVTNHPSAPNSSFCWENWRGPSRQF-------------YKVSILLLGYLLPL------LLICCCYTRILWHLHKKMKNM-SRKSQRSKQKTAQTVLLVVTAFTICWMPHHIIAMWVEFGTFPLNDASLAFRIVSHCLSYGHSCVNPILYAFLSKNFRRAF 292
[Close]
BLAST of GCR317 vs. Ensembl Medaka
Match: ENSORLT00000046303.1 (galanin receptor type 1 [Source:NCBI gene;Acc:101175549])

HSP 1 Score: 155.606 bits (392), Expect = 4.979e-43
Identity = 99/306 (32.35%), Postives = 165/306 (53.92%), Query Frame = 3 
Query:  240 SIIVPALFGIIFVVGLLGNGLVIAVI--IRN-GHMRN--STNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAF 1142
            ++IVP +FG+ F VG++GN LV+ VI  ++N G  R+   TNI I +L+ ADL+F++FC+P   +IY    W++  FLC    Y   +T   S++TLV MS DRY+ +V P  S   R+R  +L  + + W+  ++ ++P  +H +V+   P    ++   +N+   +++              YK                   +I   Y  +L+ + +++ N  S    RS +K  + V+ V+ AF + W+P HI+ +       P N A  AF +V++ ++YG+S +NPILYAFLS+NFR AF
Sbjct:   28 AVIVPVVFGLFFAVGVVGNCLVLVVIGKVKNRGGARSLSPTNIFIVNLSVADLSFLLFCVPFEATIYSLPEWVFGGFLCKFGHYFFTVTKLVSIFTLVAMSVDRYVVVVRPKKSACARSRMSALVGLCVIWMGSLVCSVPVALH-QVVTNHPSAPNSSFCWENWRGPSRQF-------------YKVSILLLGYLLPL------LLICCCYTRILWHLHKKMKNM-SRKSQRSKQKTAQTVLLVVTAFTICWMPHHIIAMWVEFGTFPLNDASLAFRIVSHCLSYGHSCVNPILYAFLSKNFRRAF 312
[Close]
BLAST of GCR317 vs. Ensembl Medaka
Match: ENSORLT00000043882.1 (galanin receptor type 1 [Source:NCBI gene;Acc:101175549])

HSP 1 Score: 155.606 bits (392), Expect = 5.913e-43
Identity = 99/306 (32.35%), Postives = 165/306 (53.92%), Query Frame = 3 
Query:  240 SIIVPALFGIIFVVGLLGNGLVIAVI--IRN-GHMRN--STNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAF 1142
            ++IVP +FG+ F VG++GN LV+ VI  ++N G  R+   TNI I +L+ ADL+F++FC+P   +IY    W++  FLC    Y   +T   S++TLV MS DRY+ +V P  S   R+R  +L  + + W+  ++ ++P  +H +V+   P    ++   +N+   +++              YK                   +I   Y  +L+ + +++ N  S    RS +K  + V+ V+ AF + W+P HI+ +       P N A  AF +V++ ++YG+S +NPILYAFLS+NFR AF
Sbjct:   35 AVIVPVVFGLFFAVGVVGNCLVLVVIGKVKNRGGARSLSPTNIFIVNLSVADLSFLLFCVPFEATIYSLPEWVFGGFLCKFGHYFFTVTKLVSIFTLVAMSVDRYVVVVRPKKSACARSRMSALVGLCVIWMGSLVCSVPVALH-QVVTNHPSAPNSSFCWENWRGPSRQF-------------YKVSILLLGYLLPL------LLICCCYTRILWHLHKKMKNM-SRKSQRSKQKTAQTVLLVVTAFTICWMPHHIIAMWVEFGTFPLNDASLAFRIVSHCLSYGHSCVNPILYAFLSKNFRRAF 319
[Close]
BLAST of GCR317 vs. Planmine SMEST
Match: SMESG000074480.1 (SMESG000074480.1)

HSP 1 Score: 737.258 bits (1902), Expect = 0.000e+0
Identity = 398/400 (99.50%), Postives = 400/400 (100.00%), Query Frame = 3 
Query:   90 MEVMGFVLITFMLVQATGNAQKIFNFSEISINVEFPKSSNSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKISPCHLXXXXXXXXXXXXXXQNQELITKCEMETCLPLINSKD 1289
            MEVMGFVLITFMLVQATGNAQKIFNFSEISINVEFPKSSNSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLT+SIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLI+SRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKALFNHYFTFFLFGFLLPLSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKISPCHLSSSSEAAANGSNKNQNQELITKCEMETCLPLINSKD
Sbjct:    1 MEVMGFVLITFMLVQATGNAQKIFNFSEISINVEFPKSSNSSAFGMQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTISIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLINSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKALFNHYFTFFLFGFLLPLSMIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCKISPCHLSSSSEAAANGSNKNQNQELITKCEMETCLPLINSKD 400
[Close]
BLAST of GCR317 vs. Planmine SMEST
Match: SMESG000016325.1 (SMESG000016325.1)

HSP 1 Score: 261.922 bits (668), Expect = 1.019e-82
Identity = 145/317 (45.74%), Postives = 201/317 (63.41%), Query Frame = 3 
Query:  225 MQVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRI----SQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCK 1163
            M++LTS+ VP LFG+I VVG +GN LVI VII N  MRN+TNILI SLA ADL FI+FC+P T  +Y+  GW     LC IYQY+T++T YCSVYTLVLMS DRYLA+VHPI S+  R    ++ AV   W   ++ NLP LI+S ++     ++ +       YC  K  + +N     Y DD      +Y  FF+  +L P+ +I +LYG L+YR+    S ++++   A +T+  K+VT++V+ VI+ F + W P+  +F+IQ    DP    FR  H+++N +AY NSM+NP LYAFLSENFR AF   L C+
Sbjct:   31 MKILTSVAVPILFGLIMVVGFVGNLLVIVVIIANIQMRNTTNILIISLAVADLLFIIFCVPFTAVMYVTGGWPLGRVLCQIYQYMTYITAYCSVYTLVLMSIDRYLAVVHPIRSMTLRNSRNTIIAVGTVWSLFLVSNLPLLINSDIIEGPRDEITDCLVD---YCTYKPFMKWNSTKKRYEDDKVFGKIYYTLFFVMFYLWPVIIISVLYGFLIYRLLCGRSSKISHSNDAMVTK--KRVTKMVIVVIVIFTLCWAPIQTIFIIQLYGKDPGGNLFRTIHVISNCLAYSNSMVNPFLYAFLSENFRRAFANLLCCR 342
[Close]
BLAST of GCR317 vs. Planmine SMEST
Match: SMESG000014669.1 (SMESG000014669.1)

HSP 1 Score: 250.751 bits (639), Expect = 9.560e-79
Identity = 152/316 (48.10%), Postives = 199/316 (62.97%), Query Frame = 3 
Query:  231 VLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKN---YYCGNKKLVNYNEAMDGYIDDYKAXXXXXXXXXXXXXXXXXSMIVILYGLLLYRISQRLNNQ--QSANITRSNKKVTRLVVSVIIAFGVSWLPLHIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTAFKKFLTCK 1163
            VLTSI+VP LFG+I ++G  GN +V+ VII N  MRNSTNILI+SLA ADLTFI FCIP T  IY+ QGW      C IYQ+L ++T YCSVYTLVLM  DR+LA+VHPI+S   R+   +   V + WI     NLP L++S V+          +++ N   YYC    LV +N+  D Y+ D K     + +FF+F + LPL MI +LYG LL R+     ++  QS    +S K+VT +VV VI+AF   WLP+  VFL+Q    D     FR  H+ +N +AY NSM+NPILYAFLSENFR +F+  L C+
Sbjct:   24 VLTSIVVPILFGLIIILGAFGNIMVLVVIIFNKKMRNSTNILIASLAIADLTFIAFCIPFTGVIYVKQGWPLGESFCRIYQFLIYVTAYCSVYTLVLMCFDRFLAVVHPISSSLVRSDRNTFLGVVVMWILFTGTNLPLLLNSGVIK------GRKESKVNCVVYYCSYLPLVRWNDTTDQYVVDIKFGKRFFTSFFIFAYFLPLLMISLLYGKLLCRLLHGRTSKMAQSNEALKSKKRVTIMVVIVIVAFAACWLPIQSVFLLQIYEFDVGGPLFRTIHIFSNCLAYANSMVNPILYAFLSENFRRSFRDLLCCQ 333
[Close]
BLAST of GCR317 vs. Planmine SMEST
Match: SMESG000009917.1 (SMESG000009917.1)

HSP 1 Score: 173.326 bits (438), Expect = 1.297e-51
Identity = 87/183 (47.54%), Postives = 119/183 (65.03%), Query Frame = 3 
Query:  228 QVLTSIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDD 776
             ++T ++ P++FG+I V G  GN LVI V+  N  +RN TNILI+SLA AD+TFI FC+PLT +I+I +GW   +  C IYQ+ T+LT Y SVYTLVLMS DRYLA+VHPI S+  RT    L  V  +W+  ++ N P L +S V Y  P    N+   K++YC     V YNE + GY+++
Sbjct:    8 SIITEMVAPSIFGVIVVFGFFGNLLVILVVSINKQLRNGTNILIASLAIADITFITFCVPLTATIFIKKGWFLGSIACKIYQFFTYLTAYMSVYTLVLMSVDRYLAVVHPIASIPIRTEKNVLKIVLSTWVIFMLCNCPLLFNSGVAY--PPTSINDT--KDFYCTYMPTVRYNETLMGYLEN 186
[Close]
BLAST of GCR317 vs. Planmine SMEST
Match: SMESG000009917.1 (SMESG000009917.1)

HSP 1 Score: 169.088 bits (427), Expect = 3.007e-50
Identity = 86/178 (48.31%), Postives = 116/178 (65.17%), Query Frame = 3 
Query:  243 IIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTFIVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRYLAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKLANNQTRKNYYCGNKKLVNYNEAMDGYIDD 776
            ++ P++FG+I V G  GN LVI V+  N  +RN TNILI+SLA AD+TFI FC+PLT +I+I +GW   +  C IYQ+ T+LT Y SVYTLVLMS DRYLA+VHPI S+  RT    L  V  +W+  ++ N P L +S V Y  P    N+   K++YC     V YNE + GY+++
Sbjct:    1 MVAPSIFGVIVVFGFFGNLLVILVVSINKQLRNGTNILIASLAIADITFITFCVPLTATIFIKKGWFLGSIACKIYQFFTYLTAYMSVYTLVLMSVDRYLAVVHPIASIPIRTEKNVLKIVLSTWVIFMLCNCPLLFNSGVAY--PPTSINDT--KDFYCTYMPTVRYNETLMGYLEN 174
The following BLAST results are available for this feature:
BLAST of GCR317 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GALR25.898e-3929.81galanin receptor 2 [Source:HGNC Symbol;Acc:HGNC:41... [more]
GALR17.002e-3734.59galanin receptor 1 [Source:HGNC Symbol;Acc:HGNC:41... [more]
KISS1R2.258e-3227.71KISS1 receptor [Source:HGNC Symbol;Acc:HGNC:4510][more]
OPRK15.667e-3229.51opioid receptor kappa 1 [Source:HGNC Symbol;Acc:HG... [more]
OPRK15.667e-3229.51opioid receptor kappa 1 [Source:HGNC Symbol;Acc:HG... [more]
back to top
BLAST of GCR317 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
npr-92.488e-3831.10Galanin-like G-protein coupled receptor npr-9 [So... [more]
npr-357.312e-2527.73NeuroPeptide Receptor family [Source:UniProtKB/Tr... [more]
npr-228.779e-2529.47Neuropeptide receptor 22 [Source:UniProtKB/Swiss-... [more]
npr-221.094e-2429.47Neuropeptide receptor 22 [Source:UniProtKB/Swiss-... [more]
npr-342.730e-2033.57NeuroPeptide Receptor family [Source:UniProtKB/Tr... [more]
back to top
BLAST of GCR317 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
AstA-R13.581e-5436.47gene:FBgn0266429 transcript:FBtr0333798[more]
AstA-R13.581e-5436.47gene:FBgn0266429 transcript:FBtr0070575[more]
AstA-R26.515e-4638.31gene:FBgn0039595 transcript:FBtr0085316[more]
AstA-R26.515e-4638.31gene:FBgn0039595 transcript:FBtr0336790[more]
AstA-R23.559e-4538.69gene:FBgn0039595 transcript:FBtr0308641[more]
back to top
BLAST of GCR317 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
galr1b6.358e-4934.78galanin receptor 1b [Source:ZFIN;Acc:ZDB-GENE-1406... [more]
galr2b1.798e-4532.37galanin receptor 2b [Source:ZFIN;Acc:ZDB-GENE-1311... [more]
galr2b1.798e-4532.37galanin receptor 2b [Source:ZFIN;Acc:ZDB-GENE-1311... [more]
galr2a2.311e-4431.66galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-1306... [more]
galr2a2.596e-4431.46galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-1306... [more]
back to top
BLAST of GCR317 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000041298.11.201e-5033.13galanin receptor 3 [Source:NCBI gene;Acc:100488248... [more]
sp34.774e-4630.46Sp3 transcription factor [Source:Xenbase;Acc:XB-GE... [more]
sp37.299e-4630.46Sp3 transcription factor [Source:Xenbase;Acc:XB-GE... [more]
GALR26.617e-4331.41galanin receptor 2 [Source:NCBI gene;Acc:100486593... [more]
lmod39.112e-4133.96leiomodin 3 [Source:Xenbase;Acc:XB-GENE-5737414][more]
back to top
BLAST of GCR317 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Galr11.818e-3933.33galanin receptor 1 [Source:MGI Symbol;Acc:MGI:1096... [more]
Galr23.384e-3930.63galanin receptor 2 [Source:MGI Symbol;Acc:MGI:1337... [more]
Oprk17.487e-3528.20opioid receptor, kappa 1 [Source:MGI Symbol;Acc:MG... [more]
Oprk17.487e-3528.20opioid receptor, kappa 1 [Source:MGI Symbol;Acc:MG... [more]
Oprk17.487e-3528.20opioid receptor, kappa 1 [Source:MGI Symbol;Acc:MG... [more]
back to top
BLAST of GCR317 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8WPA2|AR_BOMMO1.473e-5236.74Allatostatin-A receptor OS=Bombyx mori OX=7091 GN=... [more]
sp|E7F7V7|GAL2B_DANRE1.357e-4432.37Galanin receptor 2b OS=Danio rerio OX=7955 GN=galr... [more]
sp|F1R332|GAL2A_DANRE1.960e-4331.46Galanin receptor 2a OS=Danio rerio OX=7955 GN=galr... [more]
sp|P56479|GALR1_MOUSE1.271e-3833.33Galanin receptor type 1 OS=Mus musculus OX=10090 G... [more]
sp|O88854|GALR2_MOUSE2.367e-3830.63Galanin receptor type 2 OS=Mus musculus OX=10090 G... [more]
back to top
BLAST of GCR317 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A193KUG30.000e+099.50GCR317 OS=Schmidtea mediterranea OX=79327 GN=gcr31... [more]
A0A193KUH51.124e-8046.65GCR032 OS=Schmidtea mediterranea OX=79327 GN=gcr03... [more]
A0A193KUR94.147e-7945.74GCR304 OS=Schmidtea mediterranea OX=79327 GN=gcr30... [more]
A0A193KUP03.365e-7548.10GCR064 OS=Schmidtea mediterranea OX=79327 GN=gcr06... [more]
A0A5J4NUA63.712e-7546.01Allatostatin receptor OS=Paragonimus westermani OX... [more]
back to top
BLAST of GCR317 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000006013.21.304e-4934.86pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
galr2b1.556e-4532.49galanin receptor type 2-like [Source:NCBI gene;Acc... [more]
GALR12.534e-4132.39galanin receptor type 1 [Source:NCBI gene;Acc:1030... [more]
galr1a2.977e-4031.81galanin receptor type 1 [Source:NCBI gene;Acc:1030... [more]
ENSAMXT00000053361.12.587e-3729.80G-protein coupled receptor 54 [Source:NCBI gene;Ac... [more]
back to top
BLAST of GCR317 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
galr1b1.275e-4133.33galanin receptor 1b [Source:ZFIN;Acc:ZDB-GENE-1406... [more]
galr2a5.748e-3929.97galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-1306... [more]
galr1a8.774e-3929.88galanin receptor 1a [Source:ZFIN;Acc:ZDB-GENE-0605... [more]
kiss1rb1.372e-3631.78KISS1 receptor b [Source:ZFIN;Acc:ZDB-GENE-060526-... [more]
prlh2r4.372e-3029.50prolactin releasing hormone 2 receptor [Source:ZFI... [more]
back to top
BLAST of GCR317 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of GCR317 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO499111.633e-2830.32Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO363771.125e-2730.97Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO444181.532e-2528.28Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO500211.869e-2531.51Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO391816.889e-2526.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of GCR317 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
galr2a8.482e-4632.15galanin receptor type 2 [Source:NCBI gene;Acc:1011... [more]
ENSORLT00000036456.13.270e-4332.25galanin receptor type 1 [Source:NCBI gene;Acc:1011... [more]
ENSORLT00000000456.24.198e-4332.35galanin receptor type 1 [Source:NCBI gene;Acc:1011... [more]
ENSORLT00000046303.14.979e-4332.35galanin receptor type 1 [Source:NCBI gene;Acc:1011... [more]
ENSORLT00000043882.15.913e-4332.35galanin receptor type 1 [Source:NCBI gene;Acc:1011... [more]
back to top
BLAST of GCR317 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000074480.10.000e+099.50SMESG000074480.1[more]
SMESG000016325.11.019e-8245.74SMESG000016325.1[more]
SMESG000014669.19.560e-7948.10SMESG000014669.1[more]
SMESG000009917.11.297e-5147.54SMESG000009917.1[more]
SMESG000009917.13.007e-5048.31SMESG000009917.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010426 ID=SMED30010426|Name=GCR317|organism=Schmidtea mediterranea sexual|type=transcript|length=1340bp
TAATTTGAAATAACGGAGCAAATTTGTATTTAAATAACAACAAAGTTTGT
TTTTTTGAAATGTGATATACTTTGATTGGCTTATTATCAATGGAAGTGAT
GGGATTTGTGCTTATAACATTCATGCTTGTTCAAGCCACTGGAAATGCCC
AAAAAATATTCAATTTTTCTGAGATATCCATAAATGTTGAATTTCCAAAG
TCTTCAAATTCTTCAGCATTCGGCATGCAGGTCCTCACATCAATTATCGT
TCCAGCGCTATTTGGAATCATATTTGTAGTTGGACTACTAGGAAATGGTT
TAGTTATTGCTGTTATAATCCGTAATGGGCATATGAGAAATTCGACGAAT
ATTCTGATAAGCTCTCTTGCTTTTGCCGATTTGACGTTTATAGTATTTTG
CATCCCCCTTACGTTAAGTATATACATCTATCAAGGATGGATATGGAATA
ATTTCCTATGTATGATTTATCAATATTTGACGTGGTTGACAGTGTACTGT
AGTGTTTATACGCTTGTTTTAATGAGTGCTGATCGTTATTTGGCTATTGT
GCACCCAATTACGAGTGTGAATTGGAGAACAAGAAATCGCAGTTTGACCG
CAGTCTATATCTCTTGGATTGCTTTGATAATAATTAACTTACCGTTTTTA
ATACATTCTCGCGTGCTTTATACGATTCCTGTAAAATTGGCCAACAATCA
GACGAGAAAAAACTACTATTGTGGCAATAAGAAACTAGTAAATTACAATG
AAGCTATGGACGGATATATCGACGACTATAAGGCGTTATTCAATCACTAT
TTTACATTTTTTCTTTTTGGATTTTTACTACCTTTATCAATGATTGTTAT
TTTATATGGATTGCTTCTCTACCGAATATCACAAAGACTCAACAATCAAC
AGTCCGCAAATATAACAAGGTCAAACAAAAAAGTAACAAGATTGGTTGTA
AGTGTTATCATAGCATTTGGGGTGTCATGGTTGCCGTTGCATATAGTATT
TCTGATTCAGTCAACATATGGTGACCCTTCGAATGTGGCATTCCGAGCAT
TCCATATGGTAGCCAATTCAATGGCGTATGGAAACAGTATGATTAATCCG
ATTCTTTATGCGTTTCTCTCAGAGAATTTCCGTACTGCATTTAAAAAGTT
TCTAACTTGTAAAATTTCTCCTTGTCATTTGTCATCGTCCAGTGAAGCTG
CAGCTAATGGCAGCAATAAAAATCAAAATCAAGAATTAATTACAAAATGT
GAAATGGAAACTTGCTTACCTTTGATCAATTCAAAAGATTAAATTCGTTA
TCATATGGAGATAATTATAATTATATTAATAATAATAATA
back to top

protein sequence of SMED30010426-orf-1

>SMED30010426-orf-1 ID=SMED30010426-orf-1|Name=SMED30010426-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=401bp
MEVMGFVLITFMLVQATGNAQKIFNFSEISINVEFPKSSNSSAFGMQVLT
SIIVPALFGIIFVVGLLGNGLVIAVIIRNGHMRNSTNILISSLAFADLTF
IVFCIPLTLSIYIYQGWIWNNFLCMIYQYLTWLTVYCSVYTLVLMSADRY
LAIVHPITSVNWRTRNRSLTAVYISWIALIIINLPFLIHSRVLYTIPVKL
ANNQTRKNYYCGNKKLVNYNEAMDGYIDDYKALFNHYFTFFLFGFLLPLS
MIVILYGLLLYRISQRLNNQQSANITRSNKKVTRLVVSVIIAFGVSWLPL
HIVFLIQSTYGDPSNVAFRAFHMVANSMAYGNSMINPILYAFLSENFRTA
FKKFLTCKISPCHLSSSSEAAANGSNKNQNQELITKCEMETCLPLINSKD
*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0003104enteric muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR000611NPY_rcpt
IPR000276GPCR_Rhodpsn
IPR017452GPCR_Rhodpsn_7TM
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
Vocabulary: molecular function
TermDefinition
GO:0004983neuropeptide Y receptor activity
GO:0004930G-protein coupled receptor activity
GO:0004871signal transducer activity
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
GO:0007165signal transduction
GO:0007218neuropeptide signaling pathway
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000611Neuropeptide Y receptor familyPRINTSPR01012NRPEPTIDEYRcoord: 338..351
score: 39.29
coord: 78..90
score: 44.76
coord: 131..146
score: 26.99
IPR000276G protein-coupled receptor, rhodopsin-likePRINTSPR00237GPCRRHODOPSNcoord: 322..348
score: 34.44
coord: 237..260
score: 26.49
coord: 86..107
score: 34.25
coord: 53..77
score: 32.95
coord: 131..153
score: 32.67
coord: 282..306
score: 28.73
coord: 167..188
score: 19.58
IPR000276G protein-coupled receptor, rhodopsin-likeSMARTSM013817TM_GPCR_Srsx_2coord: 62..355
e-value: 5.2E-5
score: -35.6
IPR000276G protein-coupled receptor, rhodopsin-likePFAMPF000017tm_1coord: 68..340
e-value: 2.9E-45
score: 154.6
IPR000276G protein-coupled receptor, rhodopsin-likePROSITEPS00237G_PROTEIN_RECEP_F1_1coord: 137..153
NoneNo IPR availableGENE3DG3DSA:1.20.1070.10coord: 15..382
e-value: 7.0E-80
score: 270.3
NoneNo IPR availablePANTHERPTHR24230G-PROTEIN COUPLED RECEPTORcoord: 39..386
NoneNo IPR availablePANTHERPTHR24230:SF126ALLATOSTATIN A RECEPTOR 2, ISOFORM Acoord: 39..386
NoneNo IPR availableCDDcd150967tmA_AstA_R_insectcoord: 52..351
e-value: 5.26966E-87
score: 263.772
NoneNo IPR availableSIGNALP_EUKSignalP-TMSignalP-TMcoord: 1..20
score: 0.592
NoneNo IPR availableSUPERFAMILYSSF81321Family A G protein-coupled receptor-likecoord: 40..370
NoneNo IPR availableTMHMMTMhelixcoord: 53..75
NoneNo IPR availableTMHMMTMhelixcoord: 238..260
NoneNo IPR availableTMHMMTMhelixcoord: 88..110
NoneNo IPR availableTMHMMTMhelixcoord: 322..344
NoneNo IPR availableTMHMMTMhelixcoord: 168..190
NoneNo IPR availableTMHMMTMhelixcoord: 285..307
NoneNo IPR availableTMHMMTMhelixcoord: 125..147
IPR017452GPCR, rhodopsin-like, 7TMPROSITEPS50262G_PROTEIN_RECEP_F1_2coord: 68..340
score: 46.551