SMED30010406

Overview
NameSMED30010406
Smed IDSMED30010406
Length (bp)1390
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30010406 (SMED30010406) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30010406 (SMED30010406) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30010406

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
tail regionSMED30010406SMESG000009335.1 SmedASXL_007564SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
Category 3 cellSMED30010406SMESG000009335.1 dd_Smed_v4_18243_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Alignments
SMED30010406 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.002182:41435..46224 +6683
Homology
[Close]
BLAST of SMED30010406 vs. Ensembl Human
Match: TYR (tyrosinase [Source:HGNC Symbol;Acc:HGNC:12442])

HSP 1 Score: 189.889 bits (481), Expect = 7.759e-54
Identity = 127/433 (29.33%), Postives = 206/433 (47.58%), Query Frame = -3 
Query:   87 CCPKGENDLNPCG-FPSKGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVLVAMRQEYL-DYLIVEEAY-RNKPESLRL---GNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKN-------GILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGS-EFWKSKQFCEDFSVVLEGYCSPPEW---HLSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQY 1322
            CCP    D +PCG    +G C  + ++ +P G        D R  WP  ++ + C+C  NF G +C +C +G+ G NC+E+ L+ RRNI   ++ EK+     L   +     DY+I    Y + K  S  +    N++++ V +H+  +   ++      +D    +  H+   FL WHR F+L WE+  +K+       E+F+ PYWDW D   C+ICTD+ +G +   + +    L+  S F+ W++ C+  +  N       G  E        +    R      T   P+   V F LS  ++ S    K+  F   F   LEG+ SP          S+HN++H  + G+ ++   S NDP+F+ HH  +D IF+ W  +     +VYP  + P GH  +   V FIP   +  FF+ S++LGY Y
Sbjct:   35 CCPPWSGDRSPCGQLSGRGSCQNILLSNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVRRNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMHYYVSMDALLGGSEIWRD---IDFAHEAPAFLPWHRLFLLRWEQEIQKLTGD----ENFTIPYWDWRDAEKCDICTDEYMGGQHPTNPN---LLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRNPGNHDKSR------TPRLPSSADVEFCLSLTQYESGSMDKAANF--SFRNTLEGFASPLTGIADASQSSMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLQEVYPEANAPIGHNRESYMVPFIPLYRNGDFFISSKDLGYDY 449
[Close]
BLAST of SMED30010406 vs. Ensembl Human
Match: DCT (dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709])

HSP 1 Score: 170.244 bits (430), Expect = 1.239e-46
Identity = 125/439 (28.47%), Postives = 212/439 (48.29%), Query Frame = -3 
Query:   87 SLKTGTCCPK-GENDLNPCGFP-SKGECLTVTINESPSGWDN-----YKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCS-EKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAYRN-------KPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWV-DKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRF-GSEFWKSKQFCEDFSVVLEGYCSPPEWHLSR--SLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQY 1340
            SL    CCP+ G    N CG    +G+C  V  +  P  W        +D R LWP+ +F + C+C  NF G +C DC +G+ G NC  +K  + R+NI S + +E+E  +  L +A ++ + DY+I  + +         +P+     +V++  V +H+ + R  ++   R  +     + +H+   F+TWHR+ +L  E    +  ++L   E F+ PYW++   +  C++CTD L G+      DD   ++  S+F+ W+  C+  D  N ++           +  ++ R  +    PT   +R  LS ++F    F+++  F   F   LEG+        S+  SLHN VH  + G+ A   ++ NDP+F+  H   D IF  W ++ +     +P    P GH    N V F P +T+E  F+ S+ LGY Y
Sbjct:   34 SLVNKECCPRLGAESANVCGSQQGRGQCTEVRADTRP--WSGPYILRNQDDRELWPRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCERKKPPVIRQNIHSLSPQEREQFLGALDLAKKRVHPDYVITTQHWLGLLGPNGTQPQFANC-SVYDFFVWLHYYSVRDTLLGPGRPYR---AIDFSHQGPAFVTWHRYHLLCLE----RDLQRLIGNESFALPYWNFATGRNECDVCTDQLFGAA---RPDDPTLISRNSRFSSWETVCDSLDDYNHLVTLCNGTYEGLLRRNQMGRNSM--KLPTLKDIRDCLSLQKFDNPPFFQNSTF--SFRNALEGFDKADGTLDSQVMSLHNLVHSFLNGTNALPHSAANDPIFVVLHSFTDAIFDEWMKRFNPPADAWPQELAPIGHNRMYNMVPFFPPVTNEELFLTSDQLGYSY 455
[Close]
BLAST of SMED30010406 vs. Ensembl Human
Match: TYRP1 (tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450])

HSP 1 Score: 167.933 bits (424), Expect = 1.130e-45
Identity = 128/447 (28.64%), Postives = 208/447 (46.53%), Query Frame = -3 
Query:   84 IFSLKTGTCCPKGENDLNPCGFPS---------KGECLTVTINE---SPSGWDNYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIV----EEAYRNKPESLRLGN--VHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWV-DKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKN--GILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSPPEWH--LSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDS-ENLGYQYD 1346
            + +L++G CCP    DL+P   P          +G C  VT +    SP    + +D R +WP  +F + C C  NF G +C  C  G++G  C ++ LI RRN++  +  EK   V  L +A R  +  ++I     EE       + +  N  ++   V  H+ + +   +   +E       + +H+   FLTWHR+ +L  EK  +++ ++      FS PYW++   K  C+ICTDDL+GS    S+ DS  ++  S F++W+V C+  +  +  G L NS       +       R +    P    V   L    F +  + S      F   +EGY  P   +    RSLHN  H  + G+  ++  S NDP+F+  H   D +F  W  + + +   +P  + P GH  + N V F P +T+   FV + +NLGY Y+
Sbjct:   33 VEALRSGMCCP----DLSPVSGPGTDRCGSSSGRGRCEAVTADSRPHSPQYPHDGRDDREVWPLRFFNRTCHCNGNFSGHNCGTCRPGWRGAACDQRVLIVRRNLLDLSKEEKNHFVRALDMAKRTTHPLFVIATRRSEEILGPDGNTPQFENISIYNYFVWTHYYSVKKTFLGVGQESFGE--VDFSHEGPAFLTWHRYHLLRLEKDMQEMLQE----PSFSLPYWNFATGKNVCDICTDDLMGSR---SNFDSTLISPNSVFSQWRVVCDSLEDYDTLGTLCNSTEDGPIRRNPAGNVARPMVQRLPEPQDVAQCLEVGLFDTPPFYSNS-TNSFRNTVEGYSDPTGKYDPAVRSLHNLAHLFLNGTGGQTHLSPNDPIFVLLHTFTDAVFDEWLRRYNADISTFPLENAPIGHNRQYNMVPFWPPVTNTEMFVTAPDNLGYTYE 465
[Close]
BLAST of SMED30010406 vs. Ensembl Human
Match: DCT (dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709])

HSP 1 Score: 154.451 bits (389), Expect = 1.059e-40
Identity = 126/472 (26.69%), Postives = 214/472 (45.34%), Query Frame = -3 
Query:   87 SLKTGTCCPK-GENDLNPCGFP-SKGECLTVTINESPSGWDN-----YKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCS-EKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAYRN-------KPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWV-DKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRF-GSEFWKSKQFCEDFSVVLEGYCSPPEWHLSR--SLHNSVHENVIGSFAESTTSTNDPLF--------------IFHHIQ-------------------IDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQY 1340
            SL    CCP+ G    N CG    +G+C  V  +  P  W        +D R LWP+ +F + C+C  NF G +C DC +G+ G NC  +K  + R+NI S + +E+E  +  L +A ++ + DY+I  + +         +P+     +V++  V +H+ + R  ++   R  +     + +H+   F+TWHR+ +L  E    +  ++L   E F+ PYW++   +  C++CTD L G+      DD   ++  S+F+ W+  C+  D  N ++           +  ++ R  +    PT   +R  LS ++F    F+++  F   F   LEG+        S+  SLHN VH  + G+ A   ++ NDP+F              I  H++                    D IF  W ++ +     +P    P GH    N V F P +T+E  F+ S+ LGY Y
Sbjct:   34 SLVNKECCPRLGAESANVCGSQQGRGQCTEVRADTRP--WSGPYILRNQDDRELWPRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCERKKPPVIRQNIHSLSPQEREQFLGALDLAKKRVHPDYVITTQHWLGLLGPNGTQPQFANC-SVYDFFVWLHYYSVRDTLLGPGRPYR---AIDFSHQGPAFVTWHRYHLLCLE----RDLQRLIGNESFALPYWNFATGRNECDVCTDQLFGAA---RPDDPTLISRNSRFSSWETVCDSLDDYNHLVTLCNGTYEGLLRRNQMGRNSM--KLPTLKDIRDCLSLQKFDNPPFFQNSTF--SFRNALEGFDKADGTLDSQVMSLHNLVHSFLNGTNALPHSAANDPIFVVISNRLLYNATTNILEHVRKEKATKELPSLHVLVLHSFTDAIFDEWMKRFNPPADAWPQELAPIGHNRMYNMVPFFPPVTNEELFLTSDQLGYSY 488
[Close]
BLAST of SMED30010406 vs. Ensembl Human
Match: DCT (dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709])

HSP 1 Score: 73.1738 bits (178), Expect = 3.883e-14
Identity = 54/199 (27.14%), Postives = 97/199 (48.74%), Query Frame = -3 
Query:  270 VFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWV-DKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSE-FWKSKQFCEDFSVVLEGYCSPPEWHLSR--SLHNSVHENVIGSFAESTTSTNDPLFI 854
              + +H+   F+TWHR+ +L  E+      ++L   E F+ PYW++   +  C++CTD L G+      DD   ++  S+F+ W+  C+  D  N ++           +  ++ R  +    PT   +R  LS ++F +  F+++  F   F   LEG+        S+  SLHN VH  + G+ A   ++ NDP+F+
Sbjct:   16 AIDFSHQGPAFVTWHRYHLLCLER----DLQRLIGNESFALPYWNFATGRNECDVCTDQLFGAA---RPDDPTLISRNSRFSSWETVCDSLDDYNHLVTLCNGTYEGLLRRNQMGRNSMK--LPTLKDIRDCLSLQKFDNPPFFQNSTF--SFRNALEGFDKADGTLDSQVMSLHNLVHSFLNGTNALPHSAANDPIFV 203
[Close]
BLAST of SMED30010406 vs. Ensembl Zebrafish
Match: tyrp1b (tyrosinase-related protein 1b [Source:ZFIN;Acc:ZDB-GENE-040718-249])

HSP 1 Score: 176.407 bits (446), Expect = 4.306e-49
Identity = 125/438 (28.54%), Postives = 208/438 (47.49%), Query Frame = -3 
Query:   84 SLKTGTCCPKGENDLN-PCG-FPSKGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAYRN--KPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVF---NLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDW-VDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKN--GILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSPPEWH--LSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEK-TSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDS-ENLGYQYD 1340
             L++GTCCP      N  CG    +G+C+++T +  P G     + +D R  WP  +F + C+C  NF G +C  C +G  G NC ++  + RRNIM  ++ EK   V+ L  A R  + D +I    ++    P+   +  V  + +  +F+   +  +S          F   + +H+  GF+TWHR+ +L  E    +  + +     F+ PYW++ +  + C+ICTDDLIG+    S  D+  +++ S F++W+V C   +     G + N+       +       R +    P    V   L    F +  + S    + F   +EGY +P   +  + RSLHN  H  + G+  ++  S NDP+F+  H   D IF  W ++ T+     YP  + P GH  + N V F P I +   FV + +NLGY Y+
Sbjct:   28 GLRSGTCCPSPTGLANDECGSISGRGQCVSITADRRPHGPQYPHDGRDDRERWPLRFFNRTCQCNGNFTGFNCGRCRHGLTGPNCDQRITVVRRNIMQMSADEKRAFVNALDQAKRTVHPDLVICTRRFQEILSPDGASV-QVENITIYNYFVWTHYYSVSKTYMGPGQQSFGGVDFSHEGPGFVTWHRYHLLQLE----RDMQDMLGDPSFALPYWNFAIGGSECDICTDDLIGAR---SSFDTNGISSNSVFSQWRVICESVEEYETLGTICNNTESSPIRRNPAGNVARPMVQRLPEPQDVIDCLELNTFDTPPYYSTS-SQSFRNTIEGYSAPQGNYDPVVRSLHNLAHLFLNGTGGQTHLSPNDPIFVLLHTFTDAIFDEWLQRHTAAGTLAYPEENAPIGHNREFNMVPFWPPIRNAEMFVSAPDNLGYTYE 456
[Close]
BLAST of SMED30010406 vs. Ensembl Zebrafish
Match: tyr (tyrosinase [Source:ZFIN;Acc:ZDB-GENE-991026-3])

HSP 1 Score: 176.022 bits (445), Expect = 7.324e-49
Identity = 128/443 (28.89%), Postives = 204/443 (46.05%), Query Frame = -3 
Query:   87 LKTGTCCPKGENDLNPCGFPS-KGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAYR--NKPESLRLGN--VHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYC------NLFD------PKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSPPEWHLS---RSL-HNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQY 1337
            L++  CCP    D + CG  S +G C  V +++ P+G     +  D R  WP  ++ + C+C  N+ G  C +C +G+ G NC+E+    RRNI   ++ E++  +  L +A      DY+IV   Y   N   +    N  V+++ V +H+  +R  ++            +  H++  FL WHR ++L WE   RK+        +F+ PYWDW D   C++CTD+L+G+   ++      ++  S F+ WKV C      NL +      P+  +L N                       PT   V   L    + +     ++    F   LEG+ + PE  L+   RSL HNS+H  + GS +    S NDP+FI HH  ID IF+ W  +       YP  + P GH      V FIP   +  +F+ ++ LGY+Y
Sbjct:   31 LQSKRCCPVWPGDGSVCGVQSGRGFCQDVLVSDLPNGPQYPHSGVDDRERWPLVFYNQTCQCAGNYMGFDCGECKFGFFGANCAERRESVRRNIFQLSTTERQRFISYLNLAKTTISPDYMIVTGTYAQMNNGSTPMFANISVYDLFVWMHYYVSRDALLGGPGNVWAD--IDFAHESAAFLPWHRVYLLFWEHEIRKLTGDF----NFTIPYWDWRDAQDCQVCTDELMGARSSLNRS---LISPSSVFSSWKVICSQPESYNLREALCDGSPEGPLLRNPGDHDRIR-----------VPRLPTSADVESVLRLTDYETG-QMDRRANLSFRNALEGFAN-PETGLAVTGRSLMHNSLHVFMNGSMSSVQGSANDPIFIIHHAFIDSIFEQWLRRHQPPRTHYPTANAPIGHNDGYFMVPFIPLYRNGDYFLSTKALGYEY 451
[Close]
BLAST of SMED30010406 vs. Ensembl Zebrafish
Match: dct (dopachrome tautomerase [Source:ZFIN;Acc:ZDB-GENE-000508-1])

HSP 1 Score: 171.014 bits (432), Expect = 4.369e-47
Identity = 125/432 (28.94%), Postives = 210/432 (48.61%), Query Frame = -3 
Query:   87 CCPK-GENDLNPCGF-PSKGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSE-KYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAY-------RNKPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWV-DKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSE-FWKSKQFCEDFSVVLEGYCSPPEWHLSRS---LHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQY 1322
            CCP  G +  N CG    +G C  V ++  P G        D R  WP  +F + CRC  NF G +C +C +G+ G NC + K  + R++I S +  E +  ++ L ++    + DY+I  + +         +P+   + ++++  V  H+ + R  ++   R  K     + +HK   F+TWHR+ +L  E+  +K+       E+F+ PYW++   ++ C++CTD L+G        D   ++ +S+F +W V C+  D  N ++         S +        +T   PT + VR  L+ + F S  ++ +  F   F   LEGY   P+  L  S   LHN VH+ + G+ A S ++ NDP+F+  H   D IF  W  +   E++ +P+   P GH    N V F P +T+E  ++ SE LGY Y
Sbjct:   36 CCPALGSDPANVCGLLAGRGNCSDVHVDSKPWGGPYSLRNVDDRERWPTKFFNRTCRCFGNFAGYNCGECKFGWTGLNCDQRKAPVLRKDIHSLSPEELQEFLNALDLSKTTVHPDYMIATQHWLGLLGPNGTEPQFSNI-SIYDFFVWQHYYSVRDTLLGPGRPFK---AIDFSHKGPAFITWHRYHLLSLERELQKLTGN----ENFAVPYWNFATGQSECDVCTDSLLGGR---DPSDPSRISPRSRFARWGVVCDSLDEYNRLVTLCNGTNEGSLRRGAAMSTNVT--LPTMNDVRSCLNLRDFDSPPYFTNSTF--SFRNALEGY-DKPDGELDTSVSNLHNLVHQFLNGTSALSHSAANDPIFLVLHAFTDAIFDEWMRRFR-ENETFPDEMAPIGHNRHYNMVPFFPPVTNEEIYIASEQLGYSY 450
[Close]
BLAST of SMED30010406 vs. Ensembl Zebrafish
Match: tyrp1a (tyrosinase-related protein 1a [Source:ZFIN;Acc:ZDB-GENE-070718-2])

HSP 1 Score: 169.474 bits (428), Expect = 1.973e-46
Identity = 123/438 (28.08%), Postives = 205/438 (46.80%), Query Frame = -3 
Query:   84 LKTGTCCPK--GENDLNPCGFP-SKGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAYR---NKPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVF---NLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDW-VDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKN--GILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSP--PEWHLSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVD-SENLGYQYD 1337
            L++  CCP   G  D +PCG    +G+C+ V+ +    G       +D R  WP+ +F + CRC  N+ G  C  C + + GE C ++  + RRN+++ ++ +K + V  L  A R  + D +I    Y        S +  N+   I N+ F+   +  +S        P F   + +H+  GFLTWHR+ +L  E+  + + +       F+ P+WD+    + C+ICTDDL+G+       DS  +++ S F+ W+V C   +  +  G + NS       +       R +    P    V   L    F +  + S    + F   +EGY +P  P   + RSLHN  H  + G+  ++  S NDP+F+  H   D IF  W  + + +   YP  + P GH  + N V F P + +   FV  +++LGY Y+
Sbjct:   32 LRSAQCCPSPNGLGD-DPCGASLGRGQCVDVSADTRAHGPQYPYTGRDDRESWPRRFFTRACRCNGNYSGFDCGRCKHAHTGEECQQRVPVVRRNVLTLSAEQKRVFVSALDQAKRTTHPDIVIATRHYSEIFGPDNSTQFQNIS--IYNL-FVWTHYYSVSKTFLGDGEPSFSAVDFSHEGPGFLTWHRYHLLQLERDMQDMLRD----PSFALPFWDFSTGGSECDICTDDLMGARSRF---DSTAISSNSIFSSWRVICESVEDYDTLGTICNSTESSPIRRNPAGNVARPMVQRLPEAQDVAACLEIDAFDTPPFYSTS-SDSFRNSIEGYSAPEGPYDPVVRSLHNLAHLFLNGTGGQTHLSPNDPIFLLLHTFTDAIFDEWLRRHTADVSSYPLENAPIGHNREFNMVPFWPPVRNAEMFVSAADSLGYSYE 457
[Close]
BLAST of SMED30010406 vs. Ensembl Zebrafish
Match: dct (dopachrome tautomerase [Source:ZFIN;Acc:ZDB-GENE-000508-1])

HSP 1 Score: 140.584 bits (353), Expect = 9.397e-37
Identity = 105/372 (28.23%), Postives = 184/372 (49.46%), Query Frame = -3 
Query:   87 NFYGPSCTDCFYGYKGENCSE-KYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAY-------RNKPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWV-DKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSE-FWKSKQFCEDFSVVLEGYCSPPEWHLSRS---LHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQY 1157
            NF G +C +C +G+ G NC + K  + R++I S +  E +  ++ L ++    + DY+I  + +         +P+   + ++++  V  H+ + R  ++   R  K     + +HK   F+TWHR+ +L  E+  +K+       E+F+ PYW++   ++ C++CTD L+G        D   ++ +S+F +W V C+  D  N ++         S +        +T   PT + VR  L+ + F S  ++ +  F   F   LEGY   P+  L  S   LHN VH+ + G+ A S ++ NDP+F+  H   D IF  W  +   E++ +P+   P GH    N V F P +T+E  ++ SE LGY Y
Sbjct:    2 NFAGYNCGECKFGWTGLNCDQRKAPVLRKDIHSLSPEELQEFLNALDLSKTTVHPDYMIATQHWLGLLGPNGTEPQFSNI-SIYDFFVWQHYYSVRDTLLGPGRPFK---AIDFSHKGPAFITWHRYHLLSLERELQKLTGN----ENFAVPYWNFATGQSECDVCTDSLLGGR---DPSDPSRISPRSRFARWGVVCDSLDEYNRLVTLCNGTNEGSLRRGAAMSTNVT--LPTMNDVRSCLNLRDFDSPPYFTNSTFS--FRNALEGY-DKPDGELDTSVSNLHNLVHQFLNGTSALSHSAANDPIFLVLHAFTDAIFDEWMRRFR-ENETFPDEMAPIGHNRHYNMVPFFPPVTNEEIYIASEQLGYSY 356
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BLAST of SMED30010406 vs. Ensembl Xenopus
Match: tyr (tyrosinase [Source:NCBI gene;Acc:100125152])

HSP 1 Score: 199.134 bits (505), Expect = 2.343e-57
Identity = 137/436 (31.42%), Postives = 206/436 (47.25%), Query Frame = -3 
Query:   84 SLKTGTCCPKGENDLNPCG-FPSKGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAYR-----NKPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNG--ILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSE-FWKSKQFCEDFSVVLEGYCSPPEWHLSRS---LHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQYD 1340
            SL +  CCP    D + CG    +G C  V +  S +G        D R  WP  ++ + C+C  NF G +C DC +G++G NC+E+  + R+ I   +S EK   V  L +A      DY+IV   Y      + P    + NV+++ V +H+ A+R + I      +D    +  H+   F+ WHR+F+L WE   +K+       E+F+ P+WDW D   C+ICTD+L+G    +    +  L+  S F  W++ C+  +  N   IL N        +      R   T   PT   V   LS   + +E   +S  F   F   LEG+  P     +RS   +HNS+H  + GS +    S NDP+F+ HH  +D IF+ W  +      +YP  + P GH      V FIP  T+  FF  S +LGY YD
Sbjct:   33 SLLSKECCPVWSGDGSSCGQLSGRGVCQDVVLTSSATGPQFPFTGVDDRENWPTVFYNRTCQCLGNFMGYNCADCKFGFRGPNCTERRTMIRKEIFRMSSAEKSKFVAYLNLAKHTTSRDYVIVTGTYAQMNNGSNPMFADI-NVYDLFVWMHYYASRDVFIGEDALWRD---IDFAHEAPAFVPWHRYFLLHWEHEIQKLTGD----ENFTIPFWDWRDAQGCDICTDELLGG---VHPTTTNLLSPASFFASWQIVCSRPEEYNAQRILCNGTGEGPLFRNPGGHDRS-RTPRLPTTAEVELCLSLTNYETEPMDRSANF--SFRNTLEGFADPRTGIANRSQSNMHNSLHVFLNGSMSSVQGSANDPVFVLHHAFVDSIFEQWLRRHGASVDIYPEANAPIGHNRGYYMVPFIPLYTNGEFFAASRDLGYDYD 454
[Close]
BLAST of SMED30010406 vs. Ensembl Xenopus
Match: dct (dopachrome tautomerase [Source:NCBI gene;Acc:549915])

HSP 1 Score: 176.407 bits (446), Expect = 6.311e-49
Identity = 127/437 (29.06%), Postives = 214/437 (48.97%), Query Frame = -3 
Query:   87 SLKTGTCCPKGENDLN-PCG-FPSKGECLTVTINESP-SGWDNYK--DSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSE-KYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAYRN-------KPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWV-DKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRF-GSEFWKSKQFCEDFSVVLEGYCSPPEW--HLSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQY 1340
            +L +  CCP   +DLN  CG    +G+C  V ++E P SG    +  D R  WP  +F  +CRC  NF G +C +C +G+ G  C + K  + R+NI S  ++E+   +D L  A    + DY+I  + + +       +P+     +++   V +H+ + R  ++   R        + +H+   F+TWHR+ +LL E+  +++       E F+ PYW++   +  C++CTD+L G+      DD   ++  S+F++W + CN  +  N ++  +    ++    QR          P+ + V+  LS   F    F+++  F   F   LEG+  P       + SLHN VH  + G+ A+S +S NDP+F+  H   D IF  W ++    D  +P    P GH    N V F P +T+E  F+ +E LGY Y
Sbjct:   27 ALTSKRCCPALGSDLNNVCGSLEGRGQCTPVVVDERPWSGPYTLRNVDDRERWPLKFFNSICRCTGNFAGFNCGECKFGWTGPTCEQRKPPVVRKNIHSLTAQERTQFLDALDQAKNTIHPDYVIATQHWLSILGPNGTEPQVANT-SIYNYFVWLHYYSVRDTLLGPGRPFT---AIDFSHQGPAFVTWHRYHLLLLERDLQRMTGN----ESFALPYWNFATGRNECDVCTDELFGAP---RLDDPNLISAGSRFSRWGIVCNSLNDYNRLV--TLCNGTNEGFLQRNPLGGAEGRLPSMEDVQKCLSLNEFDNPPFFRNSTF--SFRNALEGFDEPDGTLNSTAMSLHNLVHSFLNGTSAQSHSSANDPIFVVLHSFTDAIFDEWMKRFQPSDVAWPQELAPIGHNRMYNMVPFFPPVTNEELFLPAEQLGYVY 448
[Close]
BLAST of SMED30010406 vs. Ensembl Xenopus
Match: dct (dopachrome tautomerase [Source:NCBI gene;Acc:549915])

HSP 1 Score: 176.022 bits (445), Expect = 7.638e-49
Identity = 127/437 (29.06%), Postives = 214/437 (48.97%), Query Frame = -3 
Query:   87 SLKTGTCCPKGENDLN-PCG-FPSKGECLTVTINESP-SGWDNYK--DSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSE-KYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAYRN-------KPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWV-DKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRF-GSEFWKSKQFCEDFSVVLEGYCSPPEW--HLSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQY 1340
            +L +  CCP   +DLN  CG    +G+C  V ++E P SG    +  D R  WP  +F  +CRC  NF G +C +C +G+ G  C + K  + R+NI S  ++E+   +D L  A    + DY+I  + + +       +P+     +++   V +H+ + R  ++   R        + +H+   F+TWHR+ +LL E+  +++       E F+ PYW++   +  C++CTD+L G+      DD   ++  S+F++W + CN  +  N ++  +    ++    QR          P+ + V+  LS   F    F+++  F   F   LEG+  P       + SLHN VH  + G+ A+S +S NDP+F+  H   D IF  W ++    D  +P    P GH    N V F P +T+E  F+ +E LGY Y
Sbjct:   32 ALTSKRCCPALGSDLNNVCGSLEGRGQCTPVVVDERPWSGPYTLRNVDDRERWPLKFFNSICRCTGNFAGFNCGECKFGWTGPTCEQRKPPVVRKNIHSLTAQERTQFLDALDQAKNTIHPDYVIATQHWLSILGPNGTEPQVANT-SIYNYFVWLHYYSVRDTLLGPGRPFT---AIDFSHQGPAFVTWHRYHLLLLERDLQRMTGN----ESFALPYWNFATGRNECDVCTDELFGAP---RLDDPNLISAGSRFSRWGIVCNSLNDYNRLV--TLCNGTNEGFLQRNPLGGAEGRLPSMEDVQKCLSLNEFDNPPFFRNSTF--SFRNALEGFDEPDGTLNSTAMSLHNLVHSFLNGTSAQSHSSANDPIFVVLHSFTDAIFDEWMKRFQPSDVAWPQELAPIGHNRMYNMVPFFPPVTNEELFLPAEQLGYVY 453
[Close]
BLAST of SMED30010406 vs. Ensembl Xenopus
Match: tyrp1 (tyrosinase-related protein 1 [Source:NCBI gene;Acc:549230])

HSP 1 Score: 172.555 bits (436), Expect = 1.821e-47
Identity = 125/443 (28.22%), Postives = 204/443 (46.05%), Query Frame = -3 
Query:   84 SLKTGTCCP-----KGENDLNPCGFP-SKGECLTVTINESPSGWDNYK----DSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAYRNKPESLRLG------NVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDW-VDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKN--GILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSPPEWH--LSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAIT-HERFFVDSENLGYQYD 1340
            +L +G CCP     +  +  + CG    +G+C  VT++  P G   Y+    D R  WP  +F + CRC   FYG +C  C  G+ G+NC +   + RRNI+     EK   V+ L +A    + DY+I    Y    + ++        ++++  V  H+ +     +   +  +     + +H+   FLTWHR+ ++  E+  + + +       F+ PYW++ +    C+ICTDDL+G+    S+ D+  L+T S F++W+V C   +     G + NS       +       R +    P    V   L    F +  + S    E F   LEGY  P   +    RSLHN  H  + G+  ++  S NDP+F+  H   D +F  W  + + +   YP  + P GH  + N V F P +T +E F    ENLGY Y+
Sbjct:   36 ALLSGECCPGLFPGQSPDPNDQCGLSLGRGQCGPVTVDTRPHG-PQYRLDGLDDREQWPIRFFNRACRCNGRFYGHNCGSCKPGWTGDNCDQPVAVVRRNILELREEEKRRFVNALDLAKNTMHPDYVIATRRYAELIDPVQNTTNFENISIYDFFVWNHYYSVSKTFLGPGQGSEGG--IDFSHEGPAFLTWHRYHLMQLERDMQVMLRD----PSFALPYWNFAIGGNQCDICTDDLLGAR---SNFDANLLSTNSVFSQWQVVCEYVEDYESLGTICNSTRNSPIRRNPAGNVARPMVQRLPEPQDVALCLEVNMFDTPPFFSDS-SESFRNTLEGYSEPNGQYNPTVRSLHNLAHLFLNGTGGQTHLSPNDPIFVLLHTFTDAVFDEWIRRHNADSSQYPLENAPIGHNRQYNMVPFWPPVTNNEMFLTAPENLGYSYE 467
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BLAST of SMED30010406 vs. Ensembl Xenopus
Match: ENSXETT00000000812.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:KV460737.1:129601:132967:1 gene:ENSXETG00000006077.1 transcript:ENSXETT00000000812.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 154.451 bits (389), Expect = 3.207e-41
Identity = 103/403 (25.56%), Postives = 191/403 (47.39%), Query Frame = -3 
Query:  153 SLKTGTCCPKGENDLNPCGFPS-KGECLT-VTINESPSG-WDNYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVLVAMRQEYL-DYLIVEEAYRNKPESLRL--GNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSPPEWHLSR-SLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHPGHCFKCNQV 1340
            + +T  CCP    D + CG  S +G+C   V  +    G    Y D R+ WP++++   C C  N+ G +C  C YGY G+ C +K    R+ I   +  E++     L   +  +  DY+++    R+  ++ R    +++E+   IH+ + + +++++  +    P  N  H+   F  WHR  ++ +E+  + +       EDF+ PY+DW  + +C ICT+D +G      +D   YL+  S F  W+  C+ ++  +     +          +      + +T P+   V   L  + F +  + S      F  +LEG+ +P +      ++HN VH  + G+ ++   S++DP+F+ HH  ID+I++ W +K     KVYP  + PG    C +V
Sbjct:   29 AFQTKVCCPT-WTDGSACGSRSGRGQCRNWVAFSSFAKGQLPIYNDDRLDWPRHYYDSTCECFGNYGGFNCGYCKYGYTGKKCDQKKTRVRKEIRQLSFTERKRFFGYLALAKTTFSKDYVVLTTGDRHHRDTYRFVDASIYEVFSWIHYYSIKPIMVNSTLD----PRRNYAHRGPAFPGWHRLGLMFFEREVQHMTGD----EDFALPYYDWRGEQNCSICTNDYMGD-----NDVQGYLDPYSHFYNWRSICSGYNYPDAYCPGATDGYQERLHRKPGADP-LANTLPSFQDVENTLKWRDFDTPPYDSTA-TRSFRNILEGFMNPQDGVTDDLNIHNLVHLYMGGTMSQVPISSSDPMFLLHHNFIDKIYEVWIQKYKGSPKVYPENNEPGQDLVCARV 415
[Close]
BLAST of SMED30010406 vs. Ensembl Mouse
Match: Tyr (tyrosinase [Source:MGI Symbol;Acc:MGI:98880])

HSP 1 Score: 192.586 bits (488), Expect = 5.979e-55
Identity = 124/444 (27.93%), Postives = 206/444 (46.40%), Query Frame = -3 
Query:   87 SLKTGTCCPKGENDLNPCG-FPSKGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVLVAMRQEYLDYLIVEEAYRNKPESLRLG-----NVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFD------------PKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGS-EFWKSKQFCEDFSVVLEGYCSPPEWHL---SRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQY 1340
            +L    CCP    D +PCG    +G C  + ++ +PSG        D R  WP  ++ + C+C  NF G +C +C +G+ G NC+EK ++ RRNI   +  EK      L   +       ++      +  +         N++++ V +H+  +R  ++      +D    +  H+  GFL WHR F+LLWE+  R++       E+F+ PYWDW D  +C+ICTD+ +G       ++   L+  S F+ W++ C+  +            P+  +L N  +   +            T   P+   V F LS  ++ S    ++  F   F   LEG+ SP          S+HN++H  + G+ ++   S NDP+F+ HH  +D IF+ W  +     +VYP  + P GH      V FIP   +  FF+ S++LGY Y
Sbjct:   29 NLLAKECCPPWMGDGSPCGQLSGRGSCQDILLSSAPSGPQFPFKGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFGGPNCTEKRVLIRRNIFDLSVSEKNKFFSYLTLAKHTISSVYVIPTGTYGQMNNGSTPMFNDINIYDLFVWMHYYVSRDTLLGGSEIWRD---IDFAHEAPGFLPWHRLFLLLWEQEIRELTGD----ENFTVPYWDWRDAENCDICTDEYLGGR---HPENPNLLSPASFFSSWQIICSRSEEYNSHQVLCDGTPEGPLLRNPGNHDKAK-----------TPRLPSSADVEFCLSLTQYESGSMDRTANF--SFRNTLEGFASPLTGIADPSQSSMHNALHIFMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLLEVYPEANAPIGHNRDSYMVPFIPLYRNGDFFITSKDLGYDY 449
[Close]
BLAST of SMED30010406 vs. Ensembl Mouse
Match: Dct (dopachrome tautomerase [Source:MGI Symbol;Acc:MGI:102563])

HSP 1 Score: 171.785 bits (434), Expect = 2.654e-47
Identity = 124/439 (28.25%), Postives = 208/439 (47.38%), Query Frame = -3 
Query:   87 CCPK-GENDLNPCGF-PSKGECLTVTINESPSGWDN-----YKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCS-EKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAY------RNKPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWV-DKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPK-------NGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGS-EFWKSKQFCEDFSVVLEGYCSPPEWHLSR--SLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQY 1322
            CCP  G    N CGF   +G+C  V  +  P  W        +D R  WP+ +F + C+C  NF G +C  C +G+ G +C+ +K  I RRNI S  ++E+E  +  L +A +  + DY+I  + +            +   +V++  V +H+ + R  ++   R  K     + +H+   F+TWHR+ +L    W  +  ++L   E F+ PYW++   K  C++CTD+L+G+  +   DD   ++  S+F+ W++ C+  D         NG  E         +           +  PT  +V+  LS ++F S  F+++  F   F   LEG+        S+  +LHN  H  + G+ A   ++ NDP+F+  H   D IF  W ++ +     +P    P GH    N V F P +T+E  F+ +E LGY Y
Sbjct:   40 CCPPLGPEATNICGFLEGRGQCAEVQTDTRP--WSGPYILRNQDDREQWPRKFFNRTCKCTGNFAGYNCGGCKFGWTGPDCNRKKPAILRRNIHSLTAQEREQFLGALDLAKKSIHPDYVITTQHWLGLLGPNGTQPQIANCSVYDFFVWLHYYSVRDTLLGPGRPYK---AIDFSHQGPAFVTWHRYHLL----WLERELQRLTGNESFALPYWNFATGKNECDVCTDELLGAARQ---DDPTLISRNSRFSTWEIVCDSLDDYNRRVTLCNGTYEGLLRRNKVGRN---------NEKLPTLKNVQDCLSLQKFDSPPFFQNSTF--SFRNALEGFDKADGTLDSQVMNLHNLAHSFLNGTNALPHSAANDPVFVVLHSFTDAIFDEWLKRNNPSTDAWPQELAPIGHNRMYNMVPFFPPVTNEELFLTAEQLGYNY 455
[Close]
BLAST of SMED30010406 vs. Ensembl Mouse
Match: Tyrp1 (tyrosinase-related protein 1 [Source:MGI Symbol;Acc:MGI:98881])

HSP 1 Score: 170.629 bits (431), Expect = 7.911e-47
Identity = 126/444 (28.38%), Postives = 207/444 (46.62%), Query Frame = -3 
Query:   84 IFSLKTGTCCP----KGENDLNPCGFPS-KGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAYR-------NKPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWV-DKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKN--GILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSPPEWH--LSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDS-ENLGYQYD 1346
            I +L+ G CCP          +PCG  S +G C+ V  +  P       + KD R  WP  +F + C+C  NF G +C  C  G++G  C++K L  RRN++  +  EK   V  L +A R  +  ++I             N P+   + +V+   V  H+ + +   +   +E       + +H+   FLTWHR+ +L  E+  +++ ++      FS PYW++   K  C++CTDDL+GS    S+ DS  ++  S F++W+V C   +  +  G L NS       +       R      P    V   L  + F +  + S    + F   +EGY +P   +    RSLHN  H  + G+  ++  S NDP+F+  H   D +F  W  + + +   +P  + P GH  + N V F P +T+   FV + +NLGY Y+
Sbjct:   33 IEALRRGVCCPDLLPSSGPGTDPCGSSSGRGRCVAVIADSRPHSRHYPHDGKDDREAWPLRFFNRTCQCNDNFSGHNCGTCRPGWRGAACNQKILTVRRNLLDLSPEEKSHFVRALDMAKRTTHPQFVIATRRLEDILGPDGNTPQFENI-SVYNYFVWTHYYSVKKTFLGTGQESFGD--VDFSHEGPAFLTWHRYHLLQLERDMQEMLQE----PSFSLPYWNFATGKNVCDVCTDDLMGSR---SNFDSTLISPNSVFSQWRVVCESLEEYDTLGTLCNSTEGGPIRRNPAGNVGRPAVQRLPEPQDVTQCLEVRVFDTPPFYSNS-TDSFRNTVEGYSAPTGKYDPAVRSLHNLAHLFLNGTGGQTHLSPNDPIFVLLHTFTDAVFDEWLRRYNADISTFPLENAPIGHNRQYNMVPFWPPVTNTEMFVTAPDNLGYAYE 465
[Close]
BLAST of SMED30010406 vs. Ensembl Mouse
Match: Tyrp1 (tyrosinase-related protein 1 [Source:MGI Symbol;Acc:MGI:98881])

HSP 1 Score: 170.629 bits (431), Expect = 7.911e-47
Identity = 126/444 (28.38%), Postives = 207/444 (46.62%), Query Frame = -3 
Query:   84 IFSLKTGTCCP----KGENDLNPCGFPS-KGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAYR-------NKPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWV-DKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKN--GILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSPPEWH--LSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDS-ENLGYQYD 1346
            I +L+ G CCP          +PCG  S +G C+ V  +  P       + KD R  WP  +F + C+C  NF G +C  C  G++G  C++K L  RRN++  +  EK   V  L +A R  +  ++I             N P+   + +V+   V  H+ + +   +   +E       + +H+   FLTWHR+ +L  E+  +++ ++      FS PYW++   K  C++CTDDL+GS    S+ DS  ++  S F++W+V C   +  +  G L NS       +       R      P    V   L  + F +  + S    + F   +EGY +P   +    RSLHN  H  + G+  ++  S NDP+F+  H   D +F  W  + + +   +P  + P GH  + N V F P +T+   FV + +NLGY Y+
Sbjct:   33 IEALRRGVCCPDLLPSSGPGTDPCGSSSGRGRCVAVIADSRPHSRHYPHDGKDDREAWPLRFFNRTCQCNDNFSGHNCGTCRPGWRGAACNQKILTVRRNLLDLSPEEKSHFVRALDMAKRTTHPQFVIATRRLEDILGPDGNTPQFENI-SVYNYFVWTHYYSVKKTFLGTGQESFGD--VDFSHEGPAFLTWHRYHLLQLERDMQEMLQE----PSFSLPYWNFATGKNVCDVCTDDLMGSR---SNFDSTLISPNSVFSQWRVVCESLEEYDTLGTLCNSTEGGPIRRNPAGNVGRPAVQRLPEPQDVTQCLEVRVFDTPPFYSNS-TDSFRNTVEGYSAPTGKYDPAVRSLHNLAHLFLNGTGGQTHLSPNDPIFVLLHTFTDAVFDEWLRRYNADISTFPLENAPIGHNRQYNMVPFWPPVTNTEMFVTAPDNLGYAYE 465
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BLAST of SMED30010406 vs. Ensembl Mouse
Match: Tyrp1 (tyrosinase-related protein 1 [Source:MGI Symbol;Acc:MGI:98881])

HSP 1 Score: 85.1149 bits (209), Expect = 1.942e-18
Identity = 56/200 (28.00%), Postives = 92/200 (46.00%), Query Frame = -3 
Query:  795 IFSLKTGTCCP----KGENDLNPCGFPS-KGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAYR-------NKPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFML 1346
            I +L+ G CCP          +PCG  S +G C+ V  +  P       + KD R  WP  +F + C+C  NF G +C  C  G++G  C++K L  RRN++  +  EK   V  L +A R  +  ++I             N P+   + +V+   V  H+ + +   +   +E       + +H+   FLTWHR+ +L
Sbjct:   33 IEALRRGVCCPDLLPSSGPGTDPCGSSSGRGRCVAVIADSRPHSRHYPHDGKDDREAWPLRFFNRTCQCNDNFSGHNCGTCRPGWRGAACNQKILTVRRNLLDLSPEEKSHFVRALDMAKRTTHPQFVIATRRLEDILGPDGNTPQFENI-SVYNYFVWTHYYSVKKTFLGTGQESFGD--VDFSHEGPAFLTWHRYHLL 229
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BLAST of SMED30010406 vs. UniProt/SwissProt
Match: sp|P55024|TYRO_CHICK (Tyrosinase OS=Gallus gallus OX=9031 GN=TYR PE=2 SV=1)

HSP 1 Score: 206.838 bits (525), Expect = 1.785e-59
Identity = 140/434 (32.26%), Postives = 214/434 (49.31%), Query Frame = -3 
Query:   84 SLKTGTCCPKGENDLNPCGFPS-KGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAYRNKPES----LRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNG--ILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSPPEW--HLSRS-LHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQYD 1340
            SL    CCP  + D  PCG  S +G C  + ++++P G     +  D R  WP  ++ + CRC+ NF G +C +C +G+ G+NC+E+ L TRRNI      EK+  +  L +A      DY+I    Y           R  NV+++ V +H+ A+R  ++      +D    +  H+  GFL WHR F+LLWE+  +KI       E+F+ PYWDW D   C ICTD+ +G +   + +    L+  S F+ W+V C   +  N    L N+ S     +      +   T   P+   V F L+  ++ S     K     F   LEG+  P     ++S+S LHN++H  + GS ++   S NDP+FI HH  +D IF+ W  +     +VYP  + P GH  +   V FIP   +  FF+ S  LGY Y+
Sbjct:   29 SLLRKECCPPWDGDGTPCGERSNRGTCQRILLSQAPLGPQFPFSGVDDREDWPSVFYNRTCRCRGNFMGFNCGECKFGFSGQNCTERRLRTRRNIFQLTISEKDKFLAYLNLAKNIPSKDYVIATGTYAQMNNGSNPMFRNINVYDLFVWMHYYASRDTLLGGSNVWRD---IDFAHEAPGFLPWHRAFLLLWEREIQKITGD----ENFTIPYWDWRDAEDCVICTDEYMGGQHPTNPN---LLSPASFFSSWQVICTQSEEYNSQQALCNATSEGPILRNPGNNDKS-RTPRLPSSSEVEFCLTLTQYESGS-MDKMANYSFRNTLEGFADPHTAISNISQSGLHNALHIYMNGSMSQVQGSANDPIFILHHAFVDSIFERWLRRHRPMLEVYPAANAPIGHNRENYMVPFIPLYRNGEFFISSRELGYDYE 450
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BLAST of SMED30010406 vs. UniProt/SwissProt
Match: sp|P54834|TYRO_CANLF (Tyrosinase OS=Canis lupus familiaris OX=9615 GN=TYR PE=2 SV=2)

HSP 1 Score: 199.519 bits (506), Expect = 1.052e-56
Identity = 132/447 (29.53%), Postives = 212/447 (47.43%), Query Frame = -3 
Query:   78 SLKTGTCCPKGENDLNPCG-FPSKGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREK-EILVDVLVAMRQEYLDYLIVEEAY--RNKPESLRLG--NVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFD------------PKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFW-KSKQFCEDFSVVLEGYCSPPEW---HLSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQYDSF 1340
            SL    CCP    D +PCG    +G C  + ++ +P G        D R  WP  ++ + C+C  NF G +C +C +G+ G+NC+EK L+ R+NI   +  EK + L  + +A      DY+I    Y   N   +      N++++ V +H+  +R  ++      KD    +  H+  GFL WHR F+LLWE+  +K+       E+F+ PYWDW D  SC+ICTD+ +G     + +    L+  S F+ W++ C   +            P+  +L N  +   +            T   P+   V F LS  ++ S+   K+  F   F   LEG+ SP          S+HN++H  + G+ ++   S NDP+F+ HH  +D IF+ W  +     +VYP  + P GH  +   V FIP   +   F+ S +LGY Y + 
Sbjct:   29 SLMEKECCPPWSGDGSPCGQLSGRGACQDIILSNAPFGPQFPFTGVDDRESWPSVFYNRTCQCFGNFMGFNCGNCKFGFWGQNCTEKRLLVRKNIFDLSVPEKNKFLAYLTLAKHTTSPDYVIPTGTYGQMNNGSTPMFNDINIYDLFVWMHYYVSRDTLLGGSEIWKD---IDFAHEAPGFLPWHRLFLLLWEQEIQKLTGD----ENFTIPYWDWRDAKSCDICTDEYMGGRNPANPN---LLSPASFFSSWQIVCTRLEEYNSRQALCDGTPEGPLLRNPGNHDKAR-----------TPRLPSSADVEFCLSLTQYESDSMDKAANF--SFRNTLEGFASPLTGIADASQSSMHNALHIYMNGTMSQVPGSANDPIFLLHHAFVDSIFEQWLRRHHPLREVYPEANAPIGHNRESYMVPFIPLYRNGDLFISSRDLGYDYSNL 452
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BLAST of SMED30010406 vs. UniProt/SwissProt
Match: sp|Q8MIU0|TYRO_BOVIN (Tyrosinase OS=Bos taurus OX=9913 GN=TYR PE=2 SV=2)

HSP 1 Score: 194.126 bits (492), Expect = 9.473e-55
Identity = 131/434 (30.18%), Postives = 209/434 (48.16%), Query Frame = -3 
Query:   87 SLKTGTCCPKGENDLNPCG-FPSKGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREK-EILVDVLVAMRQEYLDYLIVEEAY-RNKPESLRLGN---VHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNG--ILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGS-EFWKSKQFCEDFSVVLEGYCSPPEW---HLSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQY 1340
            SL    CCP    D +PCG    +G C  V ++ +P G        D R  WP  ++ + C+C  NF G +C  C +G++G  C+E+ L+ RRNI   +  EK + L  + +A      DY+I    Y +    +  L N   V+++ V +H+  +R  ++ +    +D    +  H+  GFL WHR F+LLWE+  +K+       E+F+ PYWDW D  +C++CTD+ +G     + +    L+  S F+ W++ C+  +  N    L N  S     +      +   T   P+   V F LS  ++ S    K+  F   F   LEG+  P          S+HN++H  + G+ ++   S NDP+F+ HH  +D IF+ W  K      VYP  + P GH  +   V FIP   +  FF+ S++ GY Y
Sbjct:   29 SLTEKECCPPWAGDGSPCGRLSGRGSCQDVILSTAPLGPQFPFTGVDDRESWPSIFYNRTCQCFSNFMGFNCGSCKFGFRGPRCTERRLLVRRNIFDLSVPEKNKFLAYLTLAKHTTSPDYVIPTGTYGQMNHGTTPLFNDVSVYDLFVWMHYYVSRDTLLGDSEVWRD---IDFAHEAPGFLPWHRLFLLLWEQEIQKLTGD----ENFTIPYWDWRDAENCDVCTDEYMGGRNPANPN---LLSPASFFSSWQIVCSRLEEYNSRQALCNGTSEGPLLRNPGNHDKA-RTPRLPSSADVEFCLSLTQYESGSMDKAANF--SFRNTLEGFADPVTGIADASQSSMHNALHIYMNGTMSQVPGSANDPIFLLHHAFVDSIFEQWLRKYHPLQDVYPEANAPIGHNRESYMVPFIPLYRNGDFFISSKDXGYDY 449
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BLAST of SMED30010406 vs. UniProt/SwissProt
Match: sp|Q04604|TYRO_PELNI (Tyrosinase OS=Pelophylax nigromaculatus OX=8409 GN=TYR PE=2 SV=1)

HSP 1 Score: 194.126 bits (492), Expect = 1.150e-54
Identity = 134/434 (30.88%), Postives = 210/434 (48.39%), Query Frame = -3 
Query:   84 LKTGTCCPKGENDLNPCG-FPSKGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAYR--NKPESLRLGNV--HEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNG--ILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFW-KSKQFCEDFSVVLEGYCSPPEWHLSRS---LHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQYD 1337
            L +  CCP    D + CG    +G C  V  + SP G     +  D R  WP  ++ + C+C+ NF G +C +C +GY G NC+ +  + R++I    + EK+ L+  L +A      DY+I    Y   N   +    ++  +++ V IH+ A+R   + +     D    +  H+  GFL WHR ++LLWE+  +K+       ++F+ P+WDW D   CE+CTD+  G     S++    L+  S F+ W++ C+  +  N   I+ N  +     +   R  R   T   PT   V   LS   + +    +S  F   F   LEG+  P     +RS   +HNS+H  + GS +    S NDP+F+ HH  +D +F+ W  +      VYP  + P GH  + N V FIP  T+  FFV S +LGY YD
Sbjct:   34 LLSKECCPVWPGDNSSCGEVSGRGVCQDVVPSNSPVGAQFPFSGIDDRENWPIVFYNRTCQCQGNFMGYNCGECRFGYTGPNCTVRRNMIRKDIFRMTTAEKDKLIAYLNLAKHTISPDYVIATGTYEQMNNGSNPMFADISAYDLFVWIHYYASRDAFLEDGSVWAD---IDFAHEAPGFLPWHRFYLLLWEREIQKVTGD----DNFTIPFWDWRDAQQCELCTDEFFGGTHPTSNN---LLSPASFFSSWQIICSRPEEYNSLRIICNGTNEGPLLRSPGRHDRNR-TPRLPTSADVEACLSLTDYETGAMDRSANF--SFRNTLEGFAVPTSGIANRSQSSMHNSLHVFLNGSMSSVQGSANDPIFVLHHAFVDSLFEQWLRRHQPSLDVYPEANAPVGHNREYNMVPFIPLFTNGEFFVQSRDLGYDYD 454
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BLAST of SMED30010406 vs. UniProt/SwissProt
Match: sp|Q0MVP0|TYRO_PELES (Tyrosinase OS=Pelophylax esculentus OX=8401 GN=Tyr PE=1 SV=1)

HSP 1 Score: 193.741 bits (491), Expect = 1.552e-54
Identity = 137/438 (31.28%), Postives = 209/438 (47.72%), Query Frame = -3 
Query:   84 LKTGTCCPKGENDLNPCG-FPSKGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAYRNKPESLRLG--------NVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNG--ILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCE-DFSVVLEGYCSPPEWHLSRS---LHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQYD 1337
            L +  CCP    D + CG    +G C  V  + SP G     +  D R  WP  ++ + C+C+ NF G +C +C +GY G NC+ +  + R+ I    + EK+  +  L +A R    DY+I    Y    E +  G        NV+++ V +H+ A+R   + +     +    +  H+  GF  WHR F+LLWE+  +K+A      ++F+ P+WDW D   C++CTD+  G     S++    L+  S F+ W+V C+  +  N   I+ N  +     +   R  R   T   PT   V   LS   +  E     +F    F   LEGY  P     +RS   +HNS+H  + GS +    S NDP+F+ HH  +D +F+ W  +      VYP  + P GH  + N V FIP  T+  FFV S +LGY YD
Sbjct:   34 LLSKECCPVWPGDNSSCGEVSGRGVCQDVVPSNSPVGAQFPFSGIDDRENWPIVFYNRTCQCQGNFMGYNCGECRFGYTGPNCTVRRNMIRKEIFRMTTAEKDKFIAYLNLAKRTISQDYVISTGTY----EQMNNGSNPMFADINVYDLFVWLHYYASRDAFLEDGSVWAN---IDFAHEAPGFPPWHRFFLLLWEREIQKVAAD----DNFTIPFWDWRDAQQCDLCTDEFFGGTHPTSNN---LLSPASFFSSWQVICSQPEEYNRLRIICNGTNEGPLLRSPGRHDRN-RTPRLPTSADVEACLSLTDY--ETGAMDRFANFSFRNTLEGYAVPASGIANRSQSNMHNSLHVFMNGSMSNVQGSANDPIFVLHHAFVDSLFEQWLRRHQPSLDVYPEANAPVGHNREYNMVPFIPLFTNGEFFVQSRDLGYDYD 454
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BLAST of SMED30010406 vs. TrEMBL
Match: A0A183B2C3 (Uncharacterized protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS13358 PE=4 SV=1)

HSP 1 Score: 292.352 bits (747), Expect = 3.072e-90
Identity = 158/433 (36.49%), Postives = 243/433 (56.12%), Query Frame = -3 
Query:   60 TGTCCPKGENDLNPCGFPSKGECLTVTINESPSGWDNYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVLVAMRQEYLDYLIVEEAYRN------KPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFG-SEFWKSKQFCEDFSVVLEGYCSPPEWHLS-RSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNIS-HPGHCFKCNQVGFIPAITHERFFVDSENLGYQYDSFLFGKQN 1331
            +G CCP      +PCG    G C  V +   P   D  +D RM WPK +FK LC+C+ N++G +C  C+YG++G  C+ +  + RRNI+SY  +E+E+ V+++    +   +Y+++ E  R       +P+ L + N   +I   H  A+R  +  + + C      N NH  +GF+TWHR+ ML+WE+  RKIA +++   DF+ PYWDWVD T C++C +D++G+ G  ++     ++  S F+KW   C+   P++    +     +S    + L R + +  FPT   ++FALSRK F  +E  +  + C  F   LEG+C PP  + +   +HN VH  V GSF  + T+ NDPLFI HH QIDRIFQ W++        +PN    P +C +CN V FIPA+ H + FVD  +LG  YD++ FGK  
Sbjct:   40 SGVCCPIPRGGFHPCGGKGIGSCEPVFVQLEPLPLDRLQDDRMHWPKRFFKYLCKCEGNYFGVACDQCWYGWEGPLCNRRQKVVRRNILSYTPKEREMFVNIVAQTTKMNSEYVVIYEKDRVHSDPLWRPKFLDV-NYQYLIAYWHEYASRNTLYRSSKVCSAHLPMNNNHNVVGFVTWHRYLMLMWERALRKIASEMYGWHDFAIPYWDWVDSTECDVCRNDIVGAPGPWANGIRL-IHPGSPFSKWPENCS--PPEDD--SDCYGCHTSWPNFRPLHRHYRSTAFPTTKELQFALSRKTFYLTEPEEDLKKCRGFHQALEGFCGPPGLNSTFLFMHNKVHNMVAGSFCCAATAANDPLFILHHSQIDRIFQVWFQFFRPRPTDFPNHGVQPTNCRECNIVAFIPAVRHVQMFVDMRDLGIHYDNYNFGKHG 466
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BLAST of SMED30010406 vs. TrEMBL
Match: A0A3P7LI21 (Uncharacterized protein OS=Dibothriocephalus latus OX=60516 GN=DILT_LOCUS7378 PE=4 SV=1)

HSP 1 Score: 292.352 bits (747), Expect = 4.154e-90
Identity = 163/435 (37.47%), Postives = 239/435 (54.94%), Query Frame = -3 
Query:   60 TGTCCPKGENDLNPCGFPSKGECLTVTINE---SPSGWDNYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVLVAMRQEYLDYLIVEEAYRNKPESLRLGN-----VHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQF-CEDFSVVLEGYCSPPEWHLSRS-LHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYP-NISHPGHCFKCNQVGFIPAITHERFFVDSENLGYQYDSFLFGKQN 1331
            +G CCP  E     CG  ++GEC  V  N+    P GW    D R+ WP  +F + CRC+ NF+G  C +C++G++G +C  + + TRRN++S+  +E++ L+ ++ AM Q   D  ++ E   +  + LR        +H +I  IHF  +R ++  + ++C      + NH   GFLTWHR+ ML WE+  RKIA +L+   DF+ PYWDWVD   CE+CT+DL+G  G+  +     L+ +S F  +  YC+L  P   I        +       L R F  + FPT   + F LSR+ F  E  +     C  F   LEG+C  P+ + +   +HN VH  V GS   S TSTNDPLFI HH QIDRIF+ W+ +T      YP +   PG C +C  +G+IP + H +FF ++E LG +YD+F FGKQ 
Sbjct:   40 SGVCCPVSETTGAVCGGRTRGECAPVFENQDADPPPGWS--ADDRLHWPLTFFNQTCRCEGNFFGLICEECWFGWEGPDCLTRRVYTRRNVLSFTPQERKKLITIISAMPQVPTDRFVLLETDNDHSDPLRTPTFLPVTLHGLITFIHFYTSRSILFHDWQQCFKLESLDFNHNTNGFLTWHRYLMLFWERELRKIAIRLYEWHDFALPYWDWVDAEECEVCTNDLVGGAGDWLEFTR-RLDRRSVFYNFTEYCSL--PTGTI--TCQGCHAQWPNRTFLTRYFFANEFPTTTDLEFTLSRRNFFLEDPEESMVKCRSFHQALEGFCGRPDDNSTHLFMHNKVHNMVRGSHCCSATSTNDPLFILHHTQIDRIFELWFRRTQPRITEYPADHVAPGSCRECPLIGWIPVVRHVQFFKEAEKLGIRYDNFNFGKQG 467
[Close]
BLAST of SMED30010406 vs. TrEMBL
Match: A0A4E0S2V2 (Tyrosinase OS=Fasciola hepatica OX=6192 GN=D915_002718 PE=4 SV=1)

HSP 1 Score: 286.574 bits (732), Expect = 5.072e-88
Identity = 160/433 (36.95%), Postives = 237/433 (54.73%), Query Frame = -3 
Query:   60 TGTCCPKGENDLNPCGFPSKGECLTVTINESPSGWDNYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVLVAMRQEYLDYLIVEEAYRN------KPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFG-SEFWKSKQFCEDFSVVLEGYCSPPEWH-LSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNIS-HPGHCFKCNQVGFIPAITHERFFVDSENLGYQYDSFLFGKQN 1331
            +G CCP  +    PCG    G C    +   P      +D RM WP ++FK  CRC+ NF+G +C +C+YG++G  C++++ + RRNI SY  +E+E+ V+++    Q   DYLI+ E          KP+ L + +   +I   H  A+R  +  +   C      + NH  +GF TWHR+ MLLWE+  RKIA  L+   DF+ PYWDWVD T CE+C +D++G+ G   +     ++  S F++W   C+   P+ G         +S    + L R +    FPT D ++FALSRK F  S+  +  + C  F   LEG+C PP  +  S  +HN VH  V GSF  ++T+ NDP+FI HH Q+DR+FQ W+++       +PN    P +C +CN V FIPA+ H   FVD  +LG  YD++ FGK  
Sbjct:   40 SGVCCPIPKGRSEPCGGNGVGSCEPSFVQLEPLPKHMRQDDRMHWPSHFFKHTCRCEGNFFGVACDECWYGWEGPLCNKRHKVVRRNIFSYTPKEREMFVNIVAKTTQLKSDYLIIYEKEPIHSDPLWKPKFLDV-DYQYLIAYWHEYASRGTLYHSPETCDAVQKIDNNHNVVGFATWHRYLMLLWERALRKIATDLYGWHDFAIPYWDWVDNTVCEVCRNDMVGAMGPWVNGIRL-IHEGSPFSEWPENCS--PPEKGF--GCYGCHTSWPHFKPLHRHYKLTEFPTTDELQFALSRKTFYLSDPVEDLRKCRGFHQALEGFCGPPGSNGTSGYMHNKVHNMVAGSFCCASTAANDPIFILHHSQVDRVFQIWFQRYRPRPTDFPNHGVEPTNCRECNMVAFIPAVRHVEMFVDMRDLGIHYDNYDFGKHG 466
[Close]
BLAST of SMED30010406 vs. TrEMBL
Match: A0A504YN21 (Tyrosinase OS=Fasciola gigantica OX=46835 GN=FGIG_05898 PE=4 SV=1)

HSP 1 Score: 286.189 bits (731), Expect = 6.849e-88
Identity = 159/433 (36.72%), Postives = 237/433 (54.73%), Query Frame = -3 
Query:   60 TGTCCPKGENDLNPCGFPSKGECLTVTINESPSGWDNYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVLVAMRQEYLDYLIVEEAYRN------KPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFG-SEFWKSKQFCEDFSVVLEGYCSPPEWH-LSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNIS-HPGHCFKCNQVGFIPAITHERFFVDSENLGYQYDSFLFGKQN 1331
            +G CCP  +    PCG    G C    +   P      +D RM WP ++FK  C+C+ NF+G +C +C+YG++G  C++++ + RRNI SY  +E+E+ V+++    Q   DYLI+ E          +P+ L + +   +I   H  A+R  +  +   C      + NH  +GF TWHR+ MLLWE+  RKIA  L+   DF+ PYWDWVD T CE+C +D++G+ G   +     ++  S F++W   C+   P+ G         +S    + L R +    FPT D ++FALSRK F  S+  +  + C  F   LEG+C PP  +  S  +HN VH  V GSF  ++T+ NDP+FI HH Q+DRIFQ W+++       +PN    P +C +CN V FIPA+ H   FVD  +LG  YD++ FGK  
Sbjct:   40 SGVCCPIPKGGSEPCGGNGVGSCEPSFVQLEPLPKHMRQDDRMHWPSHFFKHTCKCEGNFFGVACDECWYGWEGPLCNKRHKVVRRNIFSYTPKEREMFVNIVAKTTQLKSDYLIIYEKEPIHSDPLWRPKFLDV-DYQYLIAYWHEYASRGTLYHSPETCDAVRKIDNNHNVVGFATWHRYLMLLWERALRKIATDLYGWHDFAIPYWDWVDNTVCEVCRNDMVGAMGPWVNGIRL-IHEGSPFSEWPENCS--PPEKGF--GCYGCHTSWPHFKPLHRHYKLTEFPTTDELQFALSRKTFYLSDLVEDLRKCRGFHQALEGFCGPPGSNSTSGYMHNKVHNMVAGSFCCASTAANDPIFILHHSQVDRIFQIWFQRYRPRPTDFPNHGVEPTNCRECNMVAFIPAVRHVEMFVDMRDLGIHYDNYDFGKHG 466
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BLAST of SMED30010406 vs. TrEMBL
Match: A0A074Z7G7 (Tyrosinase_Cu-bd domain-containing protein OS=Opisthorchis viverrini OX=6198 GN=T265_08937 PE=4 SV=1)

HSP 1 Score: 286.189 bits (731), Expect = 8.454e-88
Identity = 161/432 (37.27%), Postives = 234/432 (54.17%), Query Frame = -3 
Query:   60 TGTCCPKGENDLNPCGFPSKGECLTVTINESPSGWDNYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVLVAMRQEYLDYLIVEEAYRNKPESL---RLGNVH--EMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFG-SEFWKSKQFCEDFSVVLEGYCSPPEWHLSRS-LHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNIS-HPGHCFKCNQVGFIPAITHERFFVDSENLGYQYDSFLFGKQN 1331
            +G CCP  +  ++PCG    G C    I        N +D R+ WP  +FK  C+C+ N++G  C +C+YG+KG  C+++  + RRN+MS+  +EK + VD++  M   Y DY+I+ E  R   + L   R  +VH   +I  +H  A+R  +  +   C+     + NH  +GF TWHR+FML+WE+  RKIA +L+   DF+ PYWDWVD   CE+C + L+G+ G   D     ++  S F+ W   C+   P++G   N  S  S+    + L R +    FPT   ++F LSR  F   +  +  + C  F   LEG+CS P  +     +HN VH  V GSF  ++T+ NDPLF+ HH QIDRI Q W+E        YPN     G C +CN +GFIP I H + FVD   LG  YD++ FGK  
Sbjct:   39 SGVCCPIPKGAIHPCGGVGIGTCQRQYIQFEQIPKHNLRDDRLHWPSRFFKYTCQCEGNYFGVGCEECYYGWKGPLCNKREKVLRRNVMSFTKKEKRMFVDIVAHMPLTYTDYVIIHEGDRYHSDPLWKPRFMDVHLQYLIAYLHEYASRGTLYKDDFSCRFHKKLDNNHHVLGFATWHRYFMLVWERQLRKIATELYGWRDFAVPYWDWVDADKCEVCVNSLVGAPGPFVDGIRL-IHRDSPFSNWTEQCS--PPRSG--GNCISCHSAWPNFKPLNRHYKQTAFPTTRDLQFTLSRGSFYLPQKEEDDKKCRGFHQALEGFCSAPGTNEENLFMHNKVHNMVHGSFCCASTAGNDPLFLLHHSQIDRIMQVWFEHYRPRPTEYPNHGVDLGSCRECNIIGFIPTIRHVQMFVDLRQLGIYYDNYHFGKHG 465
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BLAST of SMED30010406 vs. Ensembl Cavefish
Match: tyr (tyrosinase-like [Source:NCBI gene;Acc:103040843])

HSP 1 Score: 186.422 bits (472), Expect = 9.987e-53
Identity = 125/446 (28.03%), Postives = 199/446 (44.62%), Query Frame = -3 
Query:   75 SLKTGTCCPKGENDLNPCGFPS-KGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVLVAMRQEYLDYLIVEEAYRNKPESLRLGNVHEMIVNI---------HFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKN-------GILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSPPEWHL---SRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQYDSFL 1340
            +L + +CCP    D + CG  S +G C  V +++ P G     +  D R  WP  +F + C+C  NF G +C +C +GY G  C+E+    RRNI S ++ EK+  +  L   +       ++  + R +   +  G V+ +  N+         H+  +R  ++            +  H+   FL WHR F+L WE   RK+        +F+ PYWDW D   C++CTD+L+G +  +   D  +++  S F+ WKV C L +  N       G+ E        +    R          PT   V F L    + +     ++    F   LEG+ SP          ++HN++H  + GS +    S NDP+F+ HH  ID IF+ W  K       YP  + P GH      V FIP   +  +F+ ++ LGY+Y   L
Sbjct:   30 ALTSRSCCPPWPGDGSACGANSGRGFCQDVVVSDLPDGPQYPHSGLDDREQWPLAFFNRTCQCAGNFMGYNCNECKFGYYGPTCAERRESVRRNIFSLSAAEKQTFISYLNLAKNTISPEYVIATSTRAQMNGIN-GTVNPLFANVSIYDLFVWMHYYVSRDTLLGGPGNIWQD--VDFAHEASAFLPWHRFFLLFWEHEIRKLTGDF----NFTIPYWDWRDARDCQVCTDELMGGQSSL---DPNFISPASIFSSWKVICTLPEIYNAEETLCDGVGEGPLFRNPGNHDPNR------VRRLPTSADVEFVLGLSDYETGSLD-RRANMSFRNALEGFASPETGMAVLGQSTMHNAIHVFMNGSMSSVQGSANDPIFLLHHAFIDSIFERWLRKHQPPRSHYPTSNAPIGHNDGYYMVPFIPLNKNGEYFLGTKALGYEYAYLL 458
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BLAST of SMED30010406 vs. Ensembl Cavefish
Match: TYR (tyrosinase-like [Source:NCBI gene;Acc:103041136])

HSP 1 Score: 186.422 bits (472), Expect = 1.068e-52
Identity = 127/435 (29.20%), Postives = 206/435 (47.36%), Query Frame = -3 
Query:   87 SLKTGTCCPKGENDLNPCGFPS-KGECLTVTINESPSGWDNYK----DSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAY---RNKPESL-RLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFD--PKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSPPEWHLSRS----LHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQY 1340
            +L +  CCP  E D + CG  S +G C  V ++E P+G   Y     D R  WP  ++ + CRC +N+ G +C DC +G+ G NC+E+    R+ +   ++ E++ L+  L +A      DY+I    Y    N    L R  +V+++ V +H+  +R  ++            +  H   GFL WHR F+L WE   RK+         F+ PYWDW D   CE+CTDDL+GS+  ++ +    ++  S F+ WKV C+       NG+L +        +   +  R  +    PT   V F L   ++ +     +     F   LEG+   P   L  S    +H ++H  + GS      S NDP+F+ HH  +D I++ W  +   E   YP  + P GH  +     F+P   +  +F+ S+++GY+Y
Sbjct:   30 ALLSKECCPVWEGDGSACGARSGRGVCQDVVVSEEPNG-PQYPFEGLDDRERWPLVFYNRTCRCLQNYMGHNCGDCRFGHFGPNCAERRESVRKEVFQLSTTERQKLISYLNLAKNTISQDYVIATGTYLEMNNGTNPLFRNVSVYDLFVWMHYYVSRHAMLGGTNNVWRG--VDFGHWAPGFLPWHRVFLLRWEHEIRKLTGDF----TFTIPYWDWRDAQECEVCTDDLVGSQSRLNPN---LISPASVFSSWKVICSRAPEYSLNGVLCDGREEGPLLRNPGKHDRN-LASGLPTSAEVDFTLGLSQYDTGP-MDRTANMSFRNTLEGF-GDPRTGLGNSPKLGMHAALHVFMNGSMTSVQGSANDPVFLLHHAFVDSIYEQWLRRHQPERSHYPTANAPIGHNSEYYMAPFLPLYRNGDYFLSSKDMGYEY 451
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BLAST of SMED30010406 vs. Ensembl Cavefish
Match: TYR (tyrosinase-like [Source:NCBI gene;Acc:103041136])

HSP 1 Score: 186.422 bits (472), Expect = 1.068e-52
Identity = 127/435 (29.20%), Postives = 206/435 (47.36%), Query Frame = -3 
Query:   87 SLKTGTCCPKGENDLNPCGFPS-KGECLTVTINESPSGWDNYK----DSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAY---RNKPESL-RLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFD--PKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSPPEWHLSRS----LHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQY 1340
            +L +  CCP  E D + CG  S +G C  V ++E P+G   Y     D R  WP  ++ + CRC +N+ G +C DC +G+ G NC+E+    R+ +   ++ E++ L+  L +A      DY+I    Y    N    L R  +V+++ V +H+  +R  ++            +  H   GFL WHR F+L WE   RK+         F+ PYWDW D   CE+CTDDL+GS+  ++ +    ++  S F+ WKV C+       NG+L +        +   +  R  +    PT   V F L   ++ +     +     F   LEG+   P   L  S    +H ++H  + GS      S NDP+F+ HH  +D I++ W  +   E   YP  + P GH  +     F+P   +  +F+ S+++GY+Y
Sbjct:   30 ALLSKECCPVWEGDGSACGARSGRGVCQDVVVSEEPNG-PQYPFEGLDDRERWPLVFYNRTCRCLQNYMGHNCGDCRFGHFGPNCAERRESVRKEVFQLSTTERQKLISYLNLAKNTISQDYVIATGTYLEMNNGTNPLFRNVSVYDLFVWMHYYVSRHAMLGGTNNVWRG--VDFGHWAPGFLPWHRVFLLRWEHEIRKLTGDF----TFTIPYWDWRDAQECEVCTDDLVGSQSRLNPN---LISPASVFSSWKVICSRAPEYSLNGVLCDGREEGPLLRNPGKHDRN-LASGLPTSAEVDFTLGLSQYDTGP-MDRTANMSFRNTLEGF-GDPRTGLGNSPKLGMHAALHVFMNGSMTSVQGSANDPVFLLHHAFVDSIYEQWLRRHQPERSHYPTANAPIGHNSEYYMAPFLPLYRNGDYFLSSKDMGYEY 451
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BLAST of SMED30010406 vs. Ensembl Cavefish
Match: tyrp1b (5,6-dihydroxyindole-2-carboxylic acid oxidase-like [Source:NCBI gene;Acc:103027103])

HSP 1 Score: 171.4 bits (433), Expect = 2.794e-47
Identity = 125/439 (28.47%), Postives = 205/439 (46.70%), Query Frame = -3 
Query:   84 SLKTGTCCPKGENDLN-PCGFPS-KGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAYR-------NKPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDW-VDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFD--PKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSPPEWH--LSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDS-ENLGYQYD 1340
             L++GTCCP      N  CG  + +G C+TVT +E P G     + +D R  WP  +F + C+C +NF G  C  C +G  G +C++K  + RRNI+  +S E++  ++ L  A R  + D +I    Y        N P+   +  ++   V  H+ +     +   ++       + +H+  GF+TWHR  +L  E    +  + +     F+ PYW + +  + C+ICTD+L G+     +  +   N  S F++W+V C+  +   K G + NS    +  + +     R +    P    +   L    F +  + S      F   +EGY +P   +  + RSLHN  H  + G+  ++  S NDP+F+  H   D IF  W ++ S     YP  + P GH    N V F P IT+   FV + E LGY Y+
Sbjct:   28 GLRSGTCCPSPTGRTNDECGSSTGRGRCVTVTADERPHGPQYPHSGRDDRERWPLRFFNRTCQCNENFSGHHCGRCKHGLTGPSCNQKVNVVRRNILQMSSEEQKAFINALDQAKRTVHPDLVICTRRYEEIFGADGNSPQFENI-TIYNFFVWTHYYSVGKTYMGPGQDGFGG--VDFSHEGPGFVTWHRFHLLQLE----RDMQDMLGDPTFALPYWYFAIGGSECDICTDNLFGARSNFGNGRTISAN--SVFSQWRVICDHLEEYEKLGTICNSTEGGTLRRHAGGNVDRPMVQKLPEPQDIIDCLDLDTFDTPPYYSTS-TRSFRNTIEGYSAPQGDYDPVVRSLHNLAHLFLNGTGGQTHLSPNDPIFVLLHTFTDAIFDEWLQRHSPGTVGYPEANAPIGHNRHFNMVPFWPPITNAEMFVAAPEGLGYNYE 456
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BLAST of SMED30010406 vs. Ensembl Cavefish
Match: dct (dopachrome tautomerase [Source:NCBI gene;Acc:103044028])

HSP 1 Score: 163.696 bits (413), Expect = 1.754e-44
Identity = 125/432 (28.94%), Postives = 200/432 (46.30%), Query Frame = -3 
Query:   87 CCPK-GENDLNPCGFPS-KGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSE-KYLITRRNIMSYNSREKEILVDVLVAMRQE-YLDYLIVEEAY-------RNKPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTS-CEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSE-FWKSKQFCEDFSVVLEGYCSPPEWHLSRS---LHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQY 1322
            CCP+ G N  + CG  S +G C  V ++  P G        D R  WP  +F + CRC  NF G +C +C +G+ G NC + K    R+NI+S    E +  +D L   +   + DY+I  E +          P+   + ++++  V  H+ + R  ++   R  K     + +HK   F+TWHR+ +L  E+  +K+       E+F+ PYW++    S C++CTD L+G        D   ++  S+F  W V C   D  N ++           +         +   PT + VR  L+ + F S  ++ +  F   F   LEGY   P+  +  S   LHN VH  + G+   S ++ NDP+F+  H   D IF+ W  +  D +  +P+   P GH    N V F P +T+E  ++ S  LGY Y
Sbjct:   42 CCPQLGPNPADVCGVLSGRGNCTVVRVDTKPWGGPYSLRNVDDRERWPTKFFNQTCRCFGNFAGYNCGECKFGWTGPNCDQRKAPAVRKNILSLTPVELQEFLDALDQSKNTIHPDYVIATEHWLGLLGPNGTNPQVSNI-SIYDFFVWQHYYSVRDTLLGPGRPFK---AIDFSHKGPAFITWHRYHLLSLERDLQKMTGN----ENFAVPYWNFATGGSECDVCTDSLLGGRDPA---DPTRISPGSRFTSWGVVCESLDEYNRLVTLCNGTREGPLRRGVGDSS--SPRLPTINDVRSCLNLRDFDSPPYFTNSTF--SFRNALEGY-DKPDGEMDSSMTNLHNLVHIFLNGTSGMSHSAANDPIFLVLHAFTDAIFEEWLRRF-DGNGSFPDEMAPIGHNRHYNMVPFFPPVTNEEIYITSSQLGYSY 456
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BLAST of SMED30010406 vs. Ensembl Sea Lamprey
Match: dct (dopachrome tautomerase [Source:ZFIN;Acc:ZDB-GENE-000508-1])

HSP 1 Score: 98.9821 bits (245), Expect = 4.252e-24
Identity = 70/235 (29.79%), Postives = 104/235 (44.26%), Query Frame = -3 
Query:   84 KKLFNIEDFSFPYWDWV-DKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKN--GILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRF-GSEFWKSKQFCEDFSVVLEGYCSPPEWHLSR--SLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEK-TSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQYD 764
            ++L     F+ P+WD+     +C++C DDL G        +   L+  S F++W++ CN  D  N    L N  +     +              PT+D V   L   RF G  FW +      F   LEGY  P   +     SLHN VH  + G+   S +S NDP+F+  H  +D +F  W  +   +  + +P    P GH    N V F P + ++  FV +E LGY YD
Sbjct:    2 QRLTGDPSFALPFWDFATGSAACDVCVDDLFGGPDPA---EPTLLSPVSPFSQWQIVCNSLDEYNLRVTLCNGSAEGPIRRNPGGDLSHPGAGRLPTRDDVAQCLGVARFDGEPFWTNSS--RSFRNALEGYDHPDGSYEPGVLSLHNLVHRFLNGTGGASFSSANDPVFVVLHTFVDAVFDEWMRRFRPNVTEAWPEQLAPIGHNLHYNMVPFFPPVPNQLMFVPAEELGYGYD 231
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BLAST of SMED30010406 vs. Ensembl Sea Lamprey
Match: dct (dopachrome tautomerase [Source:ZFIN;Acc:ZDB-GENE-000508-1])

HSP 1 Score: 93.5893 bits (231), Expect = 4.478e-22
Identity = 65/217 (29.95%), Postives = 98/217 (45.16%), Query Frame = -3 
Query:  222 VFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWV-DKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKN--GILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRF-GSEFWKSKQFCEDFSVVLEGYCSPPEWHLSR--SLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEK 854
              + +H+   F+TWHR+ +LL E   R I ++L     F+ P+WD+     +C++C DDL G        +   L+  S F++W++ CN  D  N    L N  +     +              PT+D V   L   RF G  FW +      F   LEGY  P   +     SLHN VH  + G+   S +S NDP+F+  H  +D +F  W  +
Sbjct:    8 AIDFSHQGPSFITWHRYHLLLLE---RDI-QRLTGDPSFALPFWDFATGSAACDVCVDDLFGGPDPA---EPTLLSPVSPFSQWQIVCNSLDEYNLRVTLCNGSAEGPIRRNPGGDLSHPGAGRLPTRDDVAQCLGVARFDGEPFWTNSS--RSFRNALEGYDHPDGSYEPGVLSLHNLVHRFLNGTGGASFSSANDPVFVVLHTFVDAVFDEWMRR 215
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BLAST of SMED30010406 vs. Ensembl Medaka
Match: tyr (tyrosinase [Source:NCBI gene;Acc:100049427])

HSP 1 Score: 194.126 bits (492), Expect = 1.419e-55
Identity = 132/440 (30.00%), Postives = 209/440 (47.50%), Query Frame = -3 
Query:   75 SLKTGTCCPKGENDLNPCG-FPSKGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLI-----VEEAYRNKPESLRLGNVHEMIVNIHFLAARFLIISNRREC-KDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNG--ILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCED-FSVVLEGYCSPPEWHLSR---SLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQYDSFL 1340
             L+T  CCP    D +PCG    +G C  V++++ P+G     +  D R  WP  +F + CRC  N+ G +C +C +GY G NC+E     RRNIMS ++ E++  +  L +A      DY+I      E     +       N +++ V IH+  +R   +       +D    +  H++  FL WHR ++L WE+  RKIA       +F+ PYWDW D  SCE+CTD+L+G    ++ +    ++  S F+ WKV C   +  N    L N+ +     +         +    PT   V F +S   +  E     +F  + F  VLEG+ SP      +   ++HN++H  + GS +    S NDP+F+ HH  ID IF+ W         +YP  + P GH      V F+P   +  + + ++ LGY+Y   L
Sbjct:   30 GLRTKECCPVWSGDGSPCGALSGRGFCADVSVSDEPNGPQYPHSGIDDRERWPLAFFNRTCRCAGNYGGFNCGECRFGYWGSNCAEYRESVRRNIMSMSTTEQQKFISYLNLAKNTINPDYVITTGTRAEMGENGESPMFSDINTYDLFVWIHYYVSRDTFLGGPGNVWRD---IDFAHESAAFLPWHRVYLLHWEQEIRKIAGDF----NFTIPYWDWRDAQSCEVCTDNLMGGRNALNPN---LISPASVFSSWKVICTQQEEYNNQEALCNATAEGPLLRNPGNHDPNRVP-RIPTTADVEFTISLPEY--ETGSMDRFANNSFRNVLEGFASPETGMAVQGQSTMHNALHVFMNGSMSSVQGSANDPIFLLHHAFIDSIFERWLRTHQPPRSIYPRTNAPIGHNDGYYMVPFLPLYRNGDYLLSNKALGYEYAYLL 456
[Close]
BLAST of SMED30010406 vs. Ensembl Medaka
Match: tyr (tyrosinase [Source:NCBI gene;Acc:100049427])

HSP 1 Score: 194.126 bits (492), Expect = 1.634e-55
Identity = 132/440 (30.00%), Postives = 209/440 (47.50%), Query Frame = -3 
Query:   75 SLKTGTCCPKGENDLNPCG-FPSKGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLI-----VEEAYRNKPESLRLGNVHEMIVNIHFLAARFLIISNRREC-KDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNG--ILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCED-FSVVLEGYCSPPEWHLSR---SLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQYDSFL 1340
             L+T  CCP    D +PCG    +G C  V++++ P+G     +  D R  WP  +F + CRC  N+ G +C +C +GY G NC+E     RRNIMS ++ E++  +  L +A      DY+I      E     +       N +++ V IH+  +R   +       +D    +  H++  FL WHR ++L WE+  RKIA       +F+ PYWDW D  SCE+CTD+L+G    ++ +    ++  S F+ WKV C   +  N    L N+ +     +         +    PT   V F +S   +  E     +F  + F  VLEG+ SP      +   ++HN++H  + GS +    S NDP+F+ HH  ID IF+ W         +YP  + P GH      V F+P   +  + + ++ LGY+Y   L
Sbjct:   37 GLRTKECCPVWSGDGSPCGALSGRGFCADVSVSDEPNGPQYPHSGIDDRERWPLAFFNRTCRCAGNYGGFNCGECRFGYWGSNCAEYRESVRRNIMSMSTTEQQKFISYLNLAKNTINPDYVITTGTRAEMGENGESPMFSDINTYDLFVWIHYYVSRDTFLGGPGNVWRD---IDFAHESAAFLPWHRVYLLHWEQEIRKIAGDF----NFTIPYWDWRDAQSCEVCTDNLMGGRNALNPN---LISPASVFSSWKVICTQQEEYNNQEALCNATAEGPLLRNPGNHDPNRVP-RIPTTADVEFTISLPEY--ETGSMDRFANNSFRNVLEGFASPETGMAVQGQSTMHNALHVFMNGSMSSVQGSANDPIFLLHHAFIDSIFERWLRTHQPPRSIYPRTNAPIGHNDGYYMVPFLPLYRNGDYLLSNKALGYEYAYLL 463
[Close]
BLAST of SMED30010406 vs. Ensembl Medaka
Match: TYR (tyrosinase [Source:NCBI gene;Acc:101171514])

HSP 1 Score: 189.889 bits (481), Expect = 6.146e-54
Identity = 129/441 (29.25%), Postives = 205/441 (46.49%), Query Frame = -3 
Query:   63 SLKTGTCCPKGENDLNPCGFPS-KGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVLVAMRQEY-LDYLIVEEAYR---NKPESLRLG-NVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKN--GILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSPPEWHLSRS---LHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQYDSFLFGKQ 1340
            +L++  CCP  + D + CG  S +G C  V++++ P G     +  D R  WP  +F + C+C  NF G +C DC +GY GE CSE+    RRN+      E+   V  L   +Q    DY++    YR   N    L     ++++ V +H+  +R  ++        +   +  H    F  WHR ++L WE   RK+         FS PYWDW D   C++CTD+L+GS   +   D   ++  S F+ WKV C+  +  N  G+L ++       +      R  +    PT   V F LS   + +E    +     F   LEG+  P     S S   +H ++H  + GS +    S NDP+F+ HH  +D I++ W  + + +   YP  + P GH        FIP   ++ +F+ S++LGY+Y   L   Q
Sbjct:   29 ALQSRECCPPWQGDGSACGARSGRGSCEDVSVSDQPDGPQYPFSGLDDREKWPLVFFNRTCQCTGNFMGFNCADCKFGYFGERCSERRESLRRNVFHLTRAERNRFVSYLNLAKQTLSSDYVVATGTYREMQNGSNPLFANVTIYDVFVWMHYYVSRNALLGGPGNVWAN--VDFAHWAPAFSPWHRVYLLHWEHEIRKLTGD----TTFSIPYWDWRDAQGCDVCTDELMGSRSPL---DPNLISPSSVFSSWKVLCSQAEEYNNRGVLCDAREEGPVQRNPGNHDRNLVA-RIPTSAEVEFTLSLPNYDTEP-MDRTANMSFRNTLEGFGDPQTGLGSSSRLGMHAALHVFMNGSMSSVQGSANDPIFLLHHAFVDSIYEQWLRRHNPDPSQYPQANAPIGHNGDYYMAPFIPLHQNKEYFISSKDLGYEYSHLLDTNQ 458
[Close]
BLAST of SMED30010406 vs. Ensembl Medaka
Match: tyrp1a (tyrosinase related protein 1 [Source:NCBI gene;Acc:101166337])

HSP 1 Score: 178.333 bits (451), Expect = 7.527e-50
Identity = 125/441 (28.34%), Postives = 210/441 (47.62%), Query Frame = -3 
Query:   81 IFSLKTGTCCPKGENDLN-PCGFPS-KGECLTVTINESPSGWD---NYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAYRN----KPESLRLGNV--HEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDW-VDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKN--GILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSPPEWH--LSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDS-ENLGYQYDS 1346
            +  L++G CCP     ++ PCGF + +G+C+++T++  P G     + +D R  WP  +F + C+C  NF G +C  C +G  G NC ++  + RR++M  ++ EK   V  L  A R  + D +I    Y +      +S +  NV  +   V  H+ +     +   +        + +H+  GF+TWHR+ +L  E    +  + +     F+ PYW++ +   +C+ICTDDL+G+       DS  L++ S F++W+V C   +  +  G + NS       +       R +    P    V   L    F +  + S    E F   +EGY +P   +  + RSLHN  H  + G+  ++  S NDP+F+  H   D IF  W  +       YP+ + P GH    N V F P +T+   FV + +NLGY Y++
Sbjct:   28 VEGLRSGQCCPSPPGFVDDPCGFSAGRGQCVSLTVDARPHGPQYPHDGRDDRERWPVRFFNRTCQCNGNFSGFNCGRCRHGLTGPNCDQRVSVVRRDVMRLSADEKRAFVSALDQAKRTVHPDLVIATRHYSDVFGPGGDSPQFENVTIYNYFVWTHYYSVSKTFLGAGQASFGG--VDFSHEGPGFVTWHRYHLLQLE----RDMQDMLQDPSFALPYWNFAIGGNTCDICTDDLMGARSTF---DSNSLSSNSIFSQWRVVCESVEDYDTLGTICNSTETSPIRRNPAGNVNRPMVQRLPEPQDVADCLQVNTFDTPPYYSTS-SESFRNTVEGYSAPKGNYDPVVRSLHNLAHLFLNGTGGQTHLSPNDPIFVLLHTYTDAIFDEWLRRHG--PAAYPDENAPIGHNRGYNMVPFWPPVTNSEMFVTAPDNLGYSYEA 456
[Close]
BLAST of SMED30010406 vs. Ensembl Medaka
Match: dct (dopachrome tautomerase [Source:NCBI gene;Acc:101166914])

HSP 1 Score: 176.022 bits (445), Expect = 4.651e-49
Identity = 126/439 (28.70%), Postives = 212/439 (48.29%), Query Frame = -3 
Query:   87 SLKTGTCCPK-GENDLNPCG-FPSKGECLTVTINESPSGWDNYK----DSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYL-ITRRNIMSYNSREKEILVDVL-VAMRQEYLDYLIVEEAY-------RNKPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWV-DKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGS-EFWKSKQFCEDFSVVLEGYCSPPEWHLSRS---LHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP-GHCFKCNQVGFIPAITHERFFVDSENLGYQY 1340
             +++  CCP  G +  + CG    +G C  V ++  P G   Y+    D R  WP  +F + CRC  NF G  C  C +G+ G NC +K   + R+NI S    E    ++VL +A    + DY+I  + +          P+   + ++++  V  H+ + R  ++   R  K     + +HK   F+TWHR+ +L  E+  ++++      E+F+ PYW++   ++ C++CTD ++G     + D+   ++ +S+F++W V CN  D  N ++           Q   ++R     T P+ + VR  L  + F S  ++ +  F   F   LEGY   P+  L  +   LHN VH  + G+ A S ++ NDP+F+  H   D IF  W  +    +  +P+   P GH    N V F P IT+E  ++ SE LGY Y
Sbjct:   27 GIQSKRCCPALGSDPADICGSLSGRGSCTAVRVDNKPWGGP-YRLRNVDDRERWPTKFFNQTCRCTGNFAGFDCGQCKFGWTGPNCDQKKAPVLRKNIHSLTQEELNEFLNVLDLAKNTIHPDYVIATQHWLGLLGPNGTDPQFANI-SIYDFFVWQHYYSVRDTLLGPGRPFK---AIDFSHKGPAFITWHRYHLLSLERELQRLSGD----ENFAIPYWNFATGQSECDVCTDSMLGGR---NPDNPSLISNQSRFSRWGVVCNSLDDYNRLVTLCNGTNEGLIQRGIMERS--NGTLPSMNDVRSCLGLRDFDSPPYFTNSSF--SFRNALEGY-EKPDGELDDAVNNLHNLVHAMLNGTSALSHSAANDPIFLVLHAFTDAIFDEWMRRFVPSNATFPDEMAPIGHNRDYNMVPFFPPITNEEIYIPSEQLGYSY 448
[Close]
BLAST of SMED30010406 vs. Planmine SMEST
Match: SMESG000009335.1 (SMESG000009335.1)

HSP 1 Score: 847.425 bits (2188), Expect = 0.000e+0
Identity = 425/428 (99.30%), Postives = 428/428 (100.00%), Query Frame = -3 
Query:   60 FSLKTGTCCPKGENDLNPCGFPSKGECLTVTINESPSGWDNYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVLVAMRQEYLDYLIVEEAYRNKPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSPPEWHLSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHPGHCFKCNQVGFIPAITHERFFVDSENLGYQYDSFLFGKQN 1343
            F+LKTGTCCPKGENDLNPCGFPSKGECLTVTINESPSGWDNYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVLVAMRQEYLDYLIVEEAYRNKPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENSCSPCSSSKQSQRLKRRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSPPEWHLSRSLHNSVH+NVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHPGHCFKCNQVGFIPAITHERFFVDSENLGYQYDSFLFGK+N
Sbjct:   26 FTLKTGTCCPKGENDLNPCGFPSKGECLTVTINESPSGWDNYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVLVAMRQEYLDYLIVEEAYRNKPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENSCSPCSSSKQSQRLKRRFITDTFPTKDHVRFALSRKRFGSEFWKSKQFCEDFSVVLEGYCSPPEWHLSRSLHNSVHDNVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHPGHCFKCNQVGFIPAITHERFFVDSENLGYQYDSFLFGKEN 453
[Close]
BLAST of SMED30010406 vs. Planmine SMEST
Match: SMESG000080469.1 (SMESG000080469.1)

HSP 1 Score: 260.381 bits (664), Expect = 2.470e-81
Identity = 147/435 (33.79%), Postives = 230/435 (52.87%), Query Frame = -3 
Query:   63 SLKTGTCCPKGENDLNPCGFPSKGECLTVTINESPSGWDNYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEI---LVDVLVAMRQEY---LDYLIVEEAYRNKPESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQF-CEDFSVVLEGYCSPPEWHLSR-SLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNI-SHPGHCFKCNQVGFIPAITHERFFVDSENLGYQYDSFLFGKQ 1340
            +  TG CCP+ + +   CG   +G C  +             D R+ WPK +F  +C C+ N++G +C +C+YG++G +C ++ +I RRNI   + R+K I   ++D  + +  EY   +D L        KP      ++  MIV +H   +R  +  +  +C++  + N NH+ IGF TWHR++M+ WE+  + IA+K F I++F+ PYWDW D+TSC+ICTDD+ G+ G     D   ++ +S F  W  +C   +P N   E+ C  C  +    ++ R + +  FPT   V F LS+ +F  +  +     CE F   LEG C   E       +HN +H  + GS   S T+ +DPLFIFHH Q DRIF+ +  +   +   YP   + PGH         +P ITH   F  S+ LGY+YD+F+FG +
Sbjct:   32 ATTTGVCCPRSKQNHEVCGGHERGICGHIDYFHEKIPEIFRYDDRVQWPKRFFHSVCHCRDNYFGIACNECWYGWEGHHCDKRTMIIRRNIKHLSKRDKYITKTVIDRSLYVPSEYSVYVDQLNANNDPLTKPTKWIPASIQYMIVFVHRFGSRATMFEDYLDCQNFGILNFNHEAIGFATWHRYYMMFWERLLQNIARKEFGIKNFALPYWDWTDQTSCDICTDDMAGAPG-FRGKDGVRISLRSPFGNWTEFCQ--EPDNAD-ESPCYGCHVTGNYGKITREWNSFEFPTSADVEFVLSKPQFHVQGERITDLACESFHRALEGMCGQSEKASDLFYMHNKIHNMIDGSMCCSGTAPSDPLFIFHHTQTDRIFEEYLNRYKPKLDEYPETNARPGHSRHSYLPAILPLITHAHLFKPSKKLGYKYDNFIFGSR 462
[Close]
BLAST of SMED30010406 vs. Planmine SMEST
Match: SMESG000049779.1 (SMESG000049779.1)

HSP 1 Score: 255.373 bits (651), Expect = 1.432e-79
Identity = 149/431 (34.57%), Postives = 223/431 (51.74%), Query Frame = -3 
Query:   63 TCCPKGENDLNPCGFPSKGECLTVTINESPSGWDNYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVLVAMRQEYLDYLIVEEAYRNKPESLR-----LGNVHEMIVNIHFLAARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYL-NTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSEFWKSKQF--CEDFSVVLEGYCSPPEWH-LSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNIS-HPGHCFKCNQVGFIPAITHERFFVDSENLGYQYDSFLFGKQ 1325
            TCCP  +    PCG   +G C  V  +  P       D RM WP  +FK++C C+ NF+G +C  C+YG++G NC  + +  RRNI S++  E+   + +L    +   ++L++EE+     + L      L    E I  IH  A+R  + +N++ C      + NH  + F TWHR  ML WE+   KIA K F  +DF+ PYWDW+D   CE+C +  +G+ G+    +  +L +  S+F+ W  YC+   P  G   + C  C   K+   L RR+I+  FP  + + F L    +  +  K      C  F + LEG+C        S  +HN VH  V GS   ++T++NDPLFI HH  IDRI + W++  S +    PN    PG+C +CN VG +P + H   F   ENLG  YD++ FGK+
Sbjct:   37 TCCPIPDGFHQPCGGVGRGVCDKVYTHWEPIARVFKNDDRMHWPTRFFKRMCNCEGNFFGIACESCWYGWEGRNCDRRVIKIRRNIFSFSELERMRFLRILEISNKMPSEFLVLEESSPEHSDPLVNPVFFLATFQEFIAFIHRYASRSTLFANKQMCSAFGYLDYNHNTVSFATWHRALMLHWERELAKIAMKEFQWKDFAIPYWDWLDAKKCEVCNNRYVGATGKYDYQNQIWLIDEGSQFHNWTEYCS---PPMG--NSKCVGCHFRKRFPPLNRRYISTEFPLTEDLLFVLRHSSYSVKDEKMNNMDNCRAFHLALEGFCGRNHSESTSLYMHNKVHNMVEGSMCCASTASNDPLFILHHSSIDRIIECWFQIYSPKTTQLPNHGVEPGNCRECNVVGHLPPVKHVEMFTKLENLGVTYDNYKFGKK 462
[Close]
BLAST of SMED30010406 vs. Planmine SMEST
Match: SMESG000002576.1 (SMESG000002576.1)

HSP 1 Score: 247.669 bits (631), Expect = 3.131e-76
Identity = 166/462 (35.93%), Postives = 235/462 (50.87%), Query Frame = -3 
Query:   69 KEIFSLKTGTCCPKGENDLNPCGFPSKGECL-----TVTINESPSGWDNYKDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYNSREKEILVDVLVAMRQEYLDYLIVEEAYRNKP-ESLRLGNVHEMIVNIHFLAARFLIISNRRECKDSPVF----NLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRF-ITDTFPTKDHVRFALSRKRFGSEFWKSKQF-------------------CEDFSVVLEGYCSPPEWHLSRSLHNSVHENVIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVY----PNISHPGHCFKCNQVGFIPAITHERFFVDSENLGYQYDSFLFG 1352
            + + S  +  CCP  E   N CGFP +G+C      T +I       +N  D R  WP   FK  CRC KNF G  C  C +G+ G NC +K +I R+N+M+ N  E +    V+   R +   Y+++ E   NK  + +    ++E++V IH  AAR  I+ +   C     F    + NH   GFLTWHRHFML WE+ +  IAK+ F+I+DF+FPYWDW  K+ C++CTDD++G  G  S  +   L+ KS F+ W   C+  D      +N C PC     S+    RF +++ FPT     F ++R     +++K+                      C+ F   LEG C         ++HN VH  V G+F  + +S NDPLFI HH QIDRIF+ W  +  +E  +Y      +   GHC+ C+ VGFIP + H   F  S N GY YDSF FG
Sbjct:   72 QNLTSYGSNVCCPIPEGFTNACGFPFRGKCSFFPLETHSILAPLPEIEN--DIRFEWPFKLFKYFCRCYKNFSGVDCGYCGFGFAGINCLKKRVIVRKNVMNLNQTELKYFRTVVNLSRFKRSSYMVLSETSGNKNLQKMLPATIYEVLVFIHQFAAR-PILEDDILCATRKTFSEYTDHNHNGPGFLTWHRHFMLEWERLSGLIAKEYFDIDDFAFPYWDWTGKSHCDVCTDDIVGGFGP-SIGNFKMLSPKSLFSNWTEICSHDD------QNPCKPCDILNSSKIKITRFWMSNKFPTT----FEVNRVLMLPDYYKTVYVRSHNPIKSYLVPTHEMFKPCKSFESSLEGSCKVEN---DFTMHNKVHNIVFGTFYSTRSSVNDPLFILHHTQIDRIFEFWLRR--NEGNLYFKFPKAVIQHGHCYFCHMVGFIPPLRHIDVFKPSNNFGYDYDSFKFG 514
[Close]
BLAST of SMED30010406 vs. Planmine SMEST
Match: SMESG000065741.1 (SMESG000065741.1)

HSP 1 Score: 159.844 bits (403), Expect = 5.480e-43
Identity = 132/480 (27.50%), Postives = 214/480 (44.58%), Query Frame = -3 
Query:   63 SLKTGTCCPKGENDLNPCGFPSKGECLTVTINESPSGWDNY------KDSRMLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENC---SEKYLITRRNIMSYNSREKEILVDVLVAMRQEYLDYLIVEEAYR-----NKPESLRLGN--VHEMIVNIHFLAARFLIISNRRE-CKDSP-VFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKLFNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKWKVYCNLFDPKNGILENXXXXXXXXXXXXXXXXRFITDTFPTKDHVRFALSRKRFGSE------------------FWKSKQFCEDFSVVLEGYCSPPEWHLSRSLHNSVHEN----------------VIGSFAESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHP--GHCFKCNQVGFIPAITHERFFVDSENLGYQYDSFLFGKQ 1340
            +L   TCCP   ND   CG P +G C    + ++ +   +        D R+ WP  +FK LC CK N+ G +C  C  G++GENC   S + +  R+NI++  S +  I + +L   + +  D+LI   +          ++++L N  +++ +V +HF A+R  +     E C D     +  HK   F TWHRH++L++E   R IA + F   +F+ PYWDW ++ +C ICT+DL+   G+I  +D     + S F KWK  C     K    +      S  +     K     D  P ++ +    S  ++ SE                  +++     +D  +   G   P   H +  +HN V EN                + G++ + TTS NDPLF+ HH  +D+IF+ W  +  +    YP  S    G       V F+P I +   F  +   GY YD+ + G +
Sbjct:   30 TLSNSTCCPI-YNDF-VCGGPFRGSCEVSILFQNHTEHSDVITGKLENDDRLNWPSRFFKFLCSCKSNYDGIACDKCKSGWQGENCEVVSPRKI--RQNILNMRSYDVFIFLSILNISKYQLADFLITNSSSNLHCDPVNEDNIQLVNASIYDTMVYLHFYASRSTMSKELMESCTDKDNKLDFAHKGPAFFTWHRHYLLMFEDLLRSIAVEQFGYYNFTLPYWDWTNQITCNICTNDLL---GDIPTEDQ---ESNSTFFKWKPIC---PQKPNDFDCHICDPSQEEPFLWRKYSSTVDRLPNQNEIDELFSINQYDSEPFNSSSFSRKSFRNFAEGYYRVHPNSDDMKMKDIGKGLP---HQNIMMHNMVKENLSFFLSKIQFFEVHSFINGTWMDFTTSPNDPLFLLHHTFMDKIFEIWLLR--NRRSTYPGKSSTPIGQHADDFIVPFLPLIRNRNLFTSANEFGYAYDNNIVGNK 491
The following BLAST results are available for this feature:
BLAST of SMED30010406 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TYR7.759e-5429.33tyrosinase [Source:HGNC Symbol;Acc:HGNC:12442][more]
DCT1.239e-4628.47dopachrome tautomerase [Source:HGNC Symbol;Acc:HGN... [more]
TYRP11.130e-4528.64tyrosinase related protein 1 [Source:HGNC Symbol;A... [more]
DCT1.059e-4026.69dopachrome tautomerase [Source:HGNC Symbol;Acc:HGN... [more]
DCT3.883e-1427.14dopachrome tautomerase [Source:HGNC Symbol;Acc:HGN... [more]
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BLAST of SMED30010406 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30010406 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30010406 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tyrp1b4.306e-4928.54tyrosinase-related protein 1b [Source:ZFIN;Acc:ZDB... [more]
tyr7.324e-4928.89tyrosinase [Source:ZFIN;Acc:ZDB-GENE-991026-3][more]
dct4.369e-4728.94dopachrome tautomerase [Source:ZFIN;Acc:ZDB-GENE-0... [more]
tyrp1a1.973e-4628.08tyrosinase-related protein 1a [Source:ZFIN;Acc:ZDB... [more]
dct9.397e-3728.23dopachrome tautomerase [Source:ZFIN;Acc:ZDB-GENE-0... [more]
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BLAST of SMED30010406 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tyr2.343e-5731.42tyrosinase [Source:NCBI gene;Acc:100125152][more]
dct6.311e-4929.06dopachrome tautomerase [Source:NCBI gene;Acc:54991... [more]
dct7.638e-4929.06dopachrome tautomerase [Source:NCBI gene;Acc:54991... [more]
tyrp11.821e-4728.22tyrosinase-related protein 1 [Source:NCBI gene;Acc... [more]
ENSXETT00000000812.13.207e-4125.56pep primary_assembly:Xenopus_tropicalis_v9.1:KV460... [more]
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BLAST of SMED30010406 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tyr5.979e-5527.93tyrosinase [Source:MGI Symbol;Acc:MGI:98880][more]
Dct2.654e-4728.25dopachrome tautomerase [Source:MGI Symbol;Acc:MGI:... [more]
Tyrp17.911e-4728.38tyrosinase-related protein 1 [Source:MGI Symbol;Ac... [more]
Tyrp17.911e-4728.38tyrosinase-related protein 1 [Source:MGI Symbol;Ac... [more]
Tyrp11.942e-1828.00tyrosinase-related protein 1 [Source:MGI Symbol;Ac... [more]
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BLAST of SMED30010406 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P55024|TYRO_CHICK1.785e-5932.26Tyrosinase OS=Gallus gallus OX=9031 GN=TYR PE=2 SV... [more]
sp|P54834|TYRO_CANLF1.052e-5629.53Tyrosinase OS=Canis lupus familiaris OX=9615 GN=TY... [more]
sp|Q8MIU0|TYRO_BOVIN9.473e-5530.18Tyrosinase OS=Bos taurus OX=9913 GN=TYR PE=2 SV=2[more]
sp|Q04604|TYRO_PELNI1.150e-5430.88Tyrosinase OS=Pelophylax nigromaculatus OX=8409 GN... [more]
sp|Q0MVP0|TYRO_PELES1.552e-5431.28Tyrosinase OS=Pelophylax esculentus OX=8401 GN=Tyr... [more]
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BLAST of SMED30010406 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A183B2C33.072e-9036.49Uncharacterized protein OS=Echinostoma caproni OX=... [more]
A0A3P7LI214.154e-9037.47Uncharacterized protein OS=Dibothriocephalus latus... [more]
A0A4E0S2V25.072e-8836.95Tyrosinase OS=Fasciola hepatica OX=6192 GN=D915_00... [more]
A0A504YN216.849e-8836.72Tyrosinase OS=Fasciola gigantica OX=46835 GN=FGIG_... [more]
A0A074Z7G78.454e-8837.27Tyrosinase_Cu-bd domain-containing protein OS=Opis... [more]
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BLAST of SMED30010406 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tyr9.987e-5328.03tyrosinase-like [Source:NCBI gene;Acc:103040843][more]
TYR1.068e-5229.20tyrosinase-like [Source:NCBI gene;Acc:103041136][more]
TYR1.068e-5229.20tyrosinase-like [Source:NCBI gene;Acc:103041136][more]
tyrp1b2.794e-4728.475,6-dihydroxyindole-2-carboxylic acid oxidase-like... [more]
dct1.754e-4428.94dopachrome tautomerase [Source:NCBI gene;Acc:10304... [more]
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BLAST of SMED30010406 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
dct4.252e-2429.79dopachrome tautomerase [Source:ZFIN;Acc:ZDB-GENE-0... [more]
dct4.478e-2229.95dopachrome tautomerase [Source:ZFIN;Acc:ZDB-GENE-0... [more]
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BLAST of SMED30010406 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30010406 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30010406 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tyr1.419e-5530.00tyrosinase [Source:NCBI gene;Acc:100049427][more]
tyr1.634e-5530.00tyrosinase [Source:NCBI gene;Acc:100049427][more]
TYR6.146e-5429.25tyrosinase [Source:NCBI gene;Acc:101171514][more]
tyrp1a7.527e-5028.34tyrosinase related protein 1 [Source:NCBI gene;Acc... [more]
dct4.651e-4928.70dopachrome tautomerase [Source:NCBI gene;Acc:10116... [more]
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BLAST of SMED30010406 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000009335.10.000e+099.30SMESG000009335.1[more]
SMESG000080469.12.470e-8133.79SMESG000080469.1[more]
SMESG000049779.11.432e-7934.57SMESG000049779.1[more]
SMESG000002576.13.131e-7635.93SMESG000002576.1[more]
SMESG000065741.15.480e-4327.50SMESG000065741.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010406 ID=SMED30010406|Name=SMED30010406|organism=Schmidtea mediterranea sexual|type=transcript|length=1390bp
TGAATTTTCAATCAATATTATTAATTTAAATTGTGTAATGAATATTCATA
TTTTCATCAATTTTGCTTTCCAAATAAAAACGAATCATATTGATATCCCA
AGTTTTCTGAATCTACAAAAAACCTTTCGTGAGTTATTGCCGGAATAAAT
CCGACTTGATTGCATTTGAAACAATGACCCGGATGGGATATATTAGGATA
AACTTTATCTTCATCTGAAGTTTTTTCCCACCATGCCTGAAATATTCTAT
CTATTTGTATATGATGAAATATAAACAGTGGATCATTTGTAGATGTCGTT
GATTCGGCAAACGATCCAATTACATTCTCATGTACAGAATTATGCAGACT
TCGTGATAAATGCCATTCTGGGGGACTACAATAACCTTCGAGTACAACTG
AAAAATCCTCGCAAAATTGTTTTGATTTCCAGAATTCGGAACCAAATCTT
TTTCGAGACAATGCAAACCTGACATGATCTTTGGTTGGAAATGTATCGGT
TATGAATCGCCTTTTCAATCTCTGTGACTGTTTACTACTGGAACATGGAG
AACATGAGTTTTCTAATATTCCGTTTTTCGGATCAAACAAATTACAATAA
ACTTTCCATTTATTGAATTTGCTTTTTGTGTTAAGGTAGAAAGAGTCATC
GTCGGAAATTTCTCCTTCACTGCCAATCAAATCATCGGTGCAAATCTCGC
AACTTGTCTTATCAACCCAATCCCAATAAGGAAATGAAAAGTCTTCAATA
TTAAATAATTTTTTAGCTATTTTTCTAGCCCATTTTTCCCACAGTAACAT
AAAATGTCGATGCCATGTAAGAAATCCAATATTTTTATGATTCAGATTGA
AAACTGGAGAGTCCTTACATTCTCTTCTGTTTGATATAATTAAAAATCTC
GCAGCTAAAAAATGGATATTGACAATCATTTCGTGTACATTTCCAAGTCT
AAGGGATTCTGGTTTATTTCTATAAGCTTCTTCGACAATCAAATAATCGA
GATATTCCTGTCTCATTGCAACTAGAACGTCAACTAAAATTTCTTTTTCA
CGGCTATTATAGGACATAATATTTCTCCTTGTTATCAAATATTTCTCAGA
GCAGTTCTCACCTTTATATCCATAAAAGCAGTCGGTGCAACTAGGACCAT
AGAAATTTTTTTTGCAACGACATAATTTCTTAAACCAATATTTTGGCCAT
AACATTCTTGAATCTTTATAATTGTCCCAACCAGATGGGCTTTCATTTAT
TGTCACTGTTAGACATTCACCTTTGCTAGGAAATCCGCAAGGGTTTAAAT
CATTTTCTCCCTTTGGACAGCATGTTCCCGTTTTCAATGAAAATATTTCT
TTTAGAAATTCTTATTATTTCTATTTGCAATTCACAAATA
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protein sequence of SMED30010406-orf-1

>SMED30010406-orf-1 ID=SMED30010406-orf-1|Name=SMED30010406-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=383bp
MLWPKYWFKKLCRCKKNFYGPSCTDCFYGYKGENCSEKYLITRRNIMSYN
SREKEILVDVLVAMRQEYLDYLIVEEAYRNKPESLRLGNVHEMIVNIHFL
AARFLIISNRRECKDSPVFNLNHKNIGFLTWHRHFMLLWEKWARKIAKKL
FNIEDFSFPYWDWVDKTSCEICTDDLIGSEGEISDDDSFYLNTKSKFNKW
KVYCNLFDPKNGILENSCSPCSSSKQSQRLKRRFITDTFPTKDHVRFALS
RKRFGSEFWKSKQFCEDFSVVLEGYCSPPEWHLSRSLHNSVHENVIGSFA
ESTTSTNDPLFIFHHIQIDRIFQAWWEKTSDEDKVYPNISHPGHCFKCNQ
VGFIPAITHERFFVDSENLGYQYDSFLFGKQN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000035Category 3 cell
PLANA:0000421tail
Vocabulary: INTERPRO
TermDefinition
IPR002227Tyrosinase_Cu-bd
IPR008922Unchr_di-copper_centre
Vocabulary: molecular function
TermDefinition
GO:0016491oxidoreductase activity
Vocabulary: biological process
TermDefinition
GO:0008152metabolic process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002227Tyrosinase copper-binding domainPRINTSPR00092TYROSINASEcoord: 123..140
score: 41.72
coord: 307..325
score: 46.19
coord: 287..298
score: 37.41
coord: 158..163
score: 65.65
IPR002227Tyrosinase copper-binding domainPFAMPF00264Tyrosinasecoord: 112..326
e-value: 1.1E-33
score: 117.4
IPR002227Tyrosinase copper-binding domainPROSITEPS00497TYROSINASE_1coord: 123..140
IPR002227Tyrosinase copper-binding domainPROSITEPS00498TYROSINASE_2coord: 308..319
IPR008922Uncharacterised domain, di-copper centreGENE3DG3DSA:1.10.1280.10coord: 38..378
e-value: 3.3E-45
score: 157.3
IPR008922Uncharacterised domain, di-copper centreSUPERFAMILYSSF48056Di-copper centre-containing domaincoord: 2..376
NoneNo IPR availablePANTHERPTHR11474:SF93TYROSINASEcoord: 3..376
NoneNo IPR availablePANTHERPTHR11474TYROSINASE FAMILY MEMBERcoord: 3..376