Voltage-dependent anion channel

Overview


Name	Voltage-dependent anion channel
Smed ID	SMED30010334
Length (bp)	2015

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Voltage-dependent anion channel (SMED30010334) t-SNE clustered cells

Violin plots show distribution of expression levels for Voltage-dependent anion channel (SMED30010334) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Voltage-dependent anion channel (SMED30010334) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Voltage-dependent anion channel (SMED30010334) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30010334

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pharynx	SMED30010334	h1SMcG0013215	dd_Smed_v4_1424_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30010334	h1SMcG0013215	dd_Smed_v4_1424_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30010334	h1SMcG0013215	dd_Smed_v4_1424_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30010334	h1SMcG0013215	dd_Smed_v4_1424_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30010334	h1SMcG0013215	dd_Smed_v4_1424_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30010334	h1SMcG0013215	dd_Smed_v4_1424_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30010334	h1SMcG0013215	OX_Smed_1.0.08717	ox_Smed_v2	PMID:24238224 Kao et al., 2013

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Homology

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BLAST of Voltage-dependent anion channel vs. Ensembl Human
Match: VDAC2 (voltage dependent anion channel 2 [Source:HGNC Symbol;Acc:HGNC:12672])

HSP 1 Score: 167.548 bits (423), Expect = 3.087e-46
Identity = 91/290 (31.38%), Postives = 166/290 (57.24%), Query Frame = 3

Query:   99 QHVMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + + IPPS++DLG+AA+D+F+K + FGL  ++V +K+ +    +  G+ N  +  ++GT ET +    YG+     W+T N L TE++   +  +GLK     +F P+TGKKS   K+SYKR+ +N+  ++ F    P ++ + V G    + +LAG  + FD     L  + FA+GY   DF + T++ D + F   IYQK+ ++ D  +++ +   +  +++ IAA+Y +  +  + +  K+N   ++G  Y   +  GV+L+LS+ +D K + +G +  GLA+  E+
Sbjct:   10 RPMCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSSYKRECINLGCDVDFDFAGPAIHGSAVFG---YEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQLHTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDPT--ASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVGLALELEA 294

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Query:   99 QHVMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + + IPPS++DLG+AA+D+F+K + FGL  ++V +K+ +    +  G+ N  +  ++GT ET +    YG+     W+T N L TE++   +  +GLK     +F P+TGKKS   K+SYKR+ +N+  ++ F    P ++ + V G    + +LAG  + FD     L  + FA+GY   DF + T++ D + F   IYQK+ ++ D  +++ +   +  +++ IAA+Y +  +  + +  K+N   ++G  Y   +  GV+L+LS+ +D K + +G +  GLA+  E+
Sbjct:   10 RPMCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSSYKRECINLGCDVDFDFAGPAIHGSAVFG---YEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQLHTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDPT--ASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVGLALELEA 294

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BLAST of Voltage-dependent anion channel vs. Ensembl Human
Match: VDAC2 (voltage dependent anion channel 2 [Source:HGNC Symbol;Acc:HGNC:12672])

HSP 1 Score: 167.162 bits (422), Expect = 5.509e-46
Identity = 91/288 (31.60%), Postives = 165/288 (57.29%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + IPPS++DLG+AA+D+F+K + FGL  ++V +K+ +    +  G+ N  +  ++GT ET +    YG+     W+T N L TE++   +  +GLK     +F P+TGKKS   K+SYKR+ +N+  ++ F    P ++ + V G    + +LAG  + FD     L  + FA+GY   DF + T++ D + F   IYQK+ ++ D  +++ +   +  +++ IAA+Y +  +  + +  K+N   ++G  Y   +  GV+L+LS+ +D K + +G +  GLA+  E+
Sbjct:   27 MCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSSYKRECINLGCDVDFDFAGPAIHGSAVFG---YEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQLHTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDPT--ASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVGLALELEA 309

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BLAST of Voltage-dependent anion channel vs. Ensembl Human
Match: VDAC1 (voltage dependent anion channel 1 [Source:HGNC Symbol;Acc:HGNC:12669])

HSP 1 Score: 164.851 bits (416), Expect = 1.967e-45
Identity = 86/288 (29.86%), Postives = 164/288 (56.94%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PP+++DLG++A+D+F K Y FGL  +++ +K++        G+ N +++ ++G+ ET +  T YG+     W+T N L TE++   +  +GLK     SF P+TGKK+   K  YKR+++N+  ++ F    P +   LVLG    + +LAG  +NF+     +    FA+GY+  +F + T++ D + F   IYQK+NK  +  +++ +   +  +++ IAA+Y I     +    K+N   ++G  Y   +  G++L+LS+ +D K + +G +  GL + +++
Sbjct:    1 MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDMDFDIAGPSIRGALVLGY---EGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPD--ACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA 283

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Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PP+++DLG++A+D+F K Y FGL  +++ +K++        G+ N +++ ++G+ ET +  T YG+     W+T N L TE++   +  +GLK     SF P+TGKK+   K  YKR+++N+  ++ F    P +   LVLG    + +LAG  +NF+     +    FA+GY+  +F + T++ D + F   IYQK+NK  +  +++ +   +  +++ IAA+Y I     +    K+N   ++G  Y   +  G++L+LS+ +D K + +G +  GL + +++
Sbjct:    1 MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDMDFDIAGPSIRGALVLGY---EGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPD--ACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA 283

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BLAST of Voltage-dependent anion channel vs. Ensembl Celegans
Match: vdac-1 (Probable voltage-dependent anion-selective channel [Source:UniProtKB/Swiss-Prot;Acc:Q21752])

HSP 1 Score: 96.6709 bits (239), Expect = 6.845e-22
Identity = 70/288 (24.31%), Postives = 136/288 (47.22%), Query Frame = 3

Query:  108 MIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSK-NDTASVAIK--GNHNIKSSSLSGTFETTH-TTNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYE 959
            M PP+F+DLG++AKDLF+K Y FG   ++  ++  D   V  K   +HNI S  L G  +  +    YGI +   W+T+N L T +    +  +GLK      + P  GK+S   K  +      + +++   +  P +N     G      +L G    FD ++  L   + A G+    + + + + + + F   +Y K+  N ++G  + +      + Y +A +Y  P  D + V+ K+N    +      +++  ++L+LS++ +    ++  + FGL + ++
Sbjct:    1 MAPPTFADLGKSAKDLFNKGYNFGFLKIDSTTRAGDNKEVEFKSAASHNIGSGKLGGNLDVKYKIPQYGITLTEKWNTENQLGTVIEVNEQFGRGLKVTLDSLYAPHAGKRSGKVKLDWALPTARVTADVGVTS-APVIN---AAGVFSRDGWLIGAAATFDSSSNKLAATSLAFGHSTPQYTLHSFVINSTDFGASLYHKVASNVEVGTQLGWKVGGNGADYALATKYA-PSRDLT-VRAKVNSSSQVAVAATHSLSPALKLTLSTQFNLAANDA--HKFGLGLEFD 280

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BLAST of Voltage-dependent anion channel vs. Ensembl Fly
Match: porin (gene:FBgn0004363 transcript:FBtr0100584)

HSP 1 Score: 148.673 bits (374), Expect = 7.125e-40
Identity = 86/287 (29.97%), Postives = 155/287 (54.01%), Query Frame = 3

Query:  108 MIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHTT-NYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            M PPS+SDLG+ A+D+F K Y FGL+ +++ +K  +       G+ N +S  + G+ ET +   +YG+ +   W+T N L TE++   + ++GLK     +F P +G K+   K +Y  + +  +S++      P +N + VLG    + +LAG    FD     L  + FA+GY   DF + T++ D   F+  I+Q+ +   D+G+ +++   +  +K+ I A+Y +   D + V+ K+N    +G  Y   + DGV L+LS+ +D K   +G +  G+ +  E+
Sbjct:    1 MAPPSYSDLGKQARDIFSKGYNFGLWKLDLKTKTSSGIEFNTAGHSNQESGKVFGSLETKYKVKDYGLTLTEKWNTDNTLFTEVAVQDQLLEGLKLSLEGNFAPQSGNKNGKFKVAYGHENVKADSDVNIDLKGPLINASAVLGY---QGWLAGYQTAFDTQQSKLTTNNFALGYTTKDFVLHTAVNDGQEFSGSIFQRTSDKLDVGVQLSWASGTSNTKFAIGAKYQL--DDDASVRAKVNNASQVGLGYQQKLRDGVTLTLSTLVDGKNFNAGGHKIGVGLELEA 282

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BLAST of Voltage-dependent anion channel vs. Ensembl Fly
Match: porin (gene:FBgn0004363 transcript:FBtr0080183)

HSP 1 Score: 148.673 bits (374), Expect = 7.125e-40
Identity = 86/287 (29.97%), Postives = 155/287 (54.01%), Query Frame = 3

Query:  108 MIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHTT-NYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            M PPS+SDLG+ A+D+F K Y FGL+ +++ +K  +       G+ N +S  + G+ ET +   +YG+ +   W+T N L TE++   + ++GLK     +F P +G K+   K +Y  + +  +S++      P +N + VLG    + +LAG    FD     L  + FA+GY   DF + T++ D   F+  I+Q+ +   D+G+ +++   +  +K+ I A+Y +   D + V+ K+N    +G  Y   + DGV L+LS+ +D K   +G +  G+ +  E+
Sbjct:    1 MAPPSYSDLGKQARDIFSKGYNFGLWKLDLKTKTSSGIEFNTAGHSNQESGKVFGSLETKYKVKDYGLTLTEKWNTDNTLFTEVAVQDQLLEGLKLSLEGNFAPQSGNKNGKFKVAYGHENVKADSDVNIDLKGPLINASAVLGY---QGWLAGYQTAFDTQQSKLTTNNFALGYTTKDFVLHTAVNDGQEFSGSIFQRTSDKLDVGVQLSWASGTSNTKFAIGAKYQL--DDDASVRAKVNNASQVGLGYQQKLRDGVTLTLSTLVDGKNFNAGGHKIGVGLELEA 282

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BLAST of Voltage-dependent anion channel vs. Ensembl Fly
Match: porin (gene:FBgn0004363 transcript:FBtr0305260)

HSP 1 Score: 148.673 bits (374), Expect = 7.125e-40
Identity = 86/287 (29.97%), Postives = 155/287 (54.01%), Query Frame = 3

Query:  108 MIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHTT-NYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            M PPS+SDLG+ A+D+F K Y FGL+ +++ +K  +       G+ N +S  + G+ ET +   +YG+ +   W+T N L TE++   + ++GLK     +F P +G K+   K +Y  + +  +S++      P +N + VLG    + +LAG    FD     L  + FA+GY   DF + T++ D   F+  I+Q+ +   D+G+ +++   +  +K+ I A+Y +   D + V+ K+N    +G  Y   + DGV L+LS+ +D K   +G +  G+ +  E+
Sbjct:    1 MAPPSYSDLGKQARDIFSKGYNFGLWKLDLKTKTSSGIEFNTAGHSNQESGKVFGSLETKYKVKDYGLTLTEKWNTDNTLFTEVAVQDQLLEGLKLSLEGNFAPQSGNKNGKFKVAYGHENVKADSDVNIDLKGPLINASAVLGY---QGWLAGYQTAFDTQQSKLTTNNFALGYTTKDFVLHTAVNDGQEFSGSIFQRTSDKLDVGVQLSWASGTSNTKFAIGAKYQL--DDDASVRAKVNNASQVGLGYQQKLRDGVTLTLSTLVDGKNFNAGGHKIGVGLELEA 282

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BLAST of Voltage-dependent anion channel vs. Ensembl Fly
Match: porin (gene:FBgn0004363 transcript:FBtr0332029)

HSP 1 Score: 148.673 bits (374), Expect = 7.125e-40
Identity = 86/287 (29.97%), Postives = 155/287 (54.01%), Query Frame = 3

Query:  108 MIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHTT-NYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            M PPS+SDLG+ A+D+F K Y FGL+ +++ +K  +       G+ N +S  + G+ ET +   +YG+ +   W+T N L TE++   + ++GLK     +F P +G K+   K +Y  + +  +S++      P +N + VLG    + +LAG    FD     L  + FA+GY   DF + T++ D   F+  I+Q+ +   D+G+ +++   +  +K+ I A+Y +   D + V+ K+N    +G  Y   + DGV L+LS+ +D K   +G +  G+ +  E+
Sbjct:    1 MAPPSYSDLGKQARDIFSKGYNFGLWKLDLKTKTSSGIEFNTAGHSNQESGKVFGSLETKYKVKDYGLTLTEKWNTDNTLFTEVAVQDQLLEGLKLSLEGNFAPQSGNKNGKFKVAYGHENVKADSDVNIDLKGPLINASAVLGY---QGWLAGYQTAFDTQQSKLTTNNFALGYTTKDFVLHTAVNDGQEFSGSIFQRTSDKLDVGVQLSWASGTSNTKFAIGAKYQL--DDDASVRAKVNNASQVGLGYQQKLRDGVTLTLSTLVDGKNFNAGGHKIGVGLELEA 282

[Close]

BLAST of Voltage-dependent anion channel vs. Ensembl Fly
Match: porin (gene:FBgn0004363 transcript:FBtr0080182)

HSP 1 Score: 148.673 bits (374), Expect = 7.125e-40
Identity = 86/287 (29.97%), Postives = 155/287 (54.01%), Query Frame = 3

Query:  108 MIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHTT-NYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            M PPS+SDLG+ A+D+F K Y FGL+ +++ +K  +       G+ N +S  + G+ ET +   +YG+ +   W+T N L TE++   + ++GLK     +F P +G K+   K +Y  + +  +S++      P +N + VLG    + +LAG    FD     L  + FA+GY   DF + T++ D   F+  I+Q+ +   D+G+ +++   +  +K+ I A+Y +   D + V+ K+N    +G  Y   + DGV L+LS+ +D K   +G +  G+ +  E+
Sbjct:    1 MAPPSYSDLGKQARDIFSKGYNFGLWKLDLKTKTSSGIEFNTAGHSNQESGKVFGSLETKYKVKDYGLTLTEKWNTDNTLFTEVAVQDQLLEGLKLSLEGNFAPQSGNKNGKFKVAYGHENVKADSDVNIDLKGPLINASAVLGY---QGWLAGYQTAFDTQQSKLTTNNFALGYTTKDFVLHTAVNDGQEFSGSIFQRTSDKLDVGVQLSWASGTSNTKFAIGAKYQL--DDDASVRAKVNNASQVGLGYQQKLRDGVTLTLSTLVDGKNFNAGGHKIGVGLELEA 282

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BLAST of Voltage-dependent anion channel vs. Ensembl Zebrafish
Match: vdac3 (voltage-dependent anion channel 3 [Source:ZFIN;Acc:ZDB-GENE-040426-2380])

HSP 1 Score: 169.088 bits (427), Expect = 9.969e-47
Identity = 97/291 (33.33%), Postives = 160/291 (54.98%), Query Frame = 3

Query:   93 KTQHVMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHTT-NYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYE 959
            K  ++ +PP+++DLG++AKD+F K Y FG   +++ +K+ +       G+ N  +   +G  ET +     G+ +   W+T NVLTTE++   +  KGLK     SF P+TGKKS   K  YKR+Y+N+  +L F    P V+   VLG    + +LAG  + FD     L  + FA+GY+  DF + T++ D + F   IYQK+N   +  +++ +   S  +++ IAA+Y +     S V  K+N   ++G  Y  ++  GV+L+LS+ IDAK   +G +  G+    E
Sbjct:   32 KHANMAVPPAYADLGKSAKDIFSKGYGFGTVKLDLKTKSQSGVEFTTGGSSNTDTGKAAGNLETKYKVKELGLSLNQKWNTDNVLTTEVTLEDQLTKGLKLGLDTSFVPNTGKKSAKLKTGYKREYMNVGCDLDFDLAGPTVHAAAVLGY---EGWLAGYQMAFDTAKSKLAQNNFALGYKAGDFQLHTNVNDGTEFGGSIYQKVNGQLETAVNLAWTAGSNNTRFGIAAKYQLDKD--SSVSAKVNNASLVGVGYTQSLRPGVKLTLSALIDAKNFNAGGHKVGMGFELE 317

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BLAST of Voltage-dependent anion channel vs. Ensembl Zebrafish
Match: vdac2 (voltage-dependent anion channel 2 [Source:ZFIN;Acc:ZDB-GENE-030131-845])

HSP 1 Score: 164.851 bits (416), Expect = 1.166e-45
Identity = 88/288 (30.56%), Postives = 165/288 (57.29%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTH-TTNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PP+++DLG++AKD+F+K Y FG+  ++V +K+ +       G+ N  +S + G+ ET +  + YG+     W+T N L TE++   +  KGLK     +F P+TGKKS   K +YKR+++N+  ++ F    P ++   V+G    + +LAG  ++FD     +  + FA+GY+  DF + T++ D S F   IYQK++   +  +++ +   S  +++ IAA+Y +     + +  K+N   ++G  Y  ++  G++L+LS+ +D K + SG +  GL +  E+
Sbjct:    1 MAVPPAYADLGKSAKDIFNKGYGFGMVKLDVKTKSASGVEFKTSGSSNTDTSKVVGSLETKYKRSEYGLTFTEKWNTDNTLGTEINIEDQIAKGLKLTFDTTFSPNTGKKSGKVKTAYKREFVNLGCDVDFDFAGPTIHGAAVVGY---EGWLAGYQMSFDTAKSKMTQNNFAVGYKTGDFQLHTNVNDGSEFGGSIYQKVSDKLETAVNLAWTAGSNSTRFGIAAKYQLDKD--ASISAKVNNTSLVGVGYTQSLRPGIKLTLSALVDGKSINSGGHKLGLGLELEA 283

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Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTH-TTNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PP+++DLG++AKD+F+K Y FG+  ++V +K+ +       G+ N  +S + G+ ET +  + YG+     W+T N L TE++   +  KGLK     +F P+TGKKS   K +YKR+++N+  ++ F    P ++   V+G    + +LAG  ++FD     +  + FA+GY+  DF + T++ D S F   IYQK++   +  +++ +   S  +++ IAA+Y +     + +  K+N   ++G  Y  ++  G++L+LS+ +D K + SG +  GL +  E+
Sbjct:    1 MAVPPAYADLGKSAKDIFNKGYGFGMVKLDVKTKSASGVEFKTSGSSNTDTSKVVGSLETKYKRSEYGLTFTEKWNTDNTLGTEINIEDQIAKGLKLTFDTTFSPNTGKKSGKVKTAYKREFVNLGCDVDFDFAGPTIHGAAVVGY---EGWLAGYQMSFDTAKSKMTQNNFAVGYKTGDFQLHTNVNDGSEFGGSIYQKVSDKLETAVNLAWTAGSNSTRFGIAAKYQLDKD--ASISAKVNNTSLVGVGYTQSLRPGIKLTLSALVDGKSINSGGHKLGLGLELEA 283

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BLAST of Voltage-dependent anion channel vs. Ensembl Zebrafish
Match: vdac1 (voltage-dependent anion channel 1 [Source:ZFIN;Acc:ZDB-GENE-030131-6514])

HSP 1 Score: 159.458 bits (402), Expect = 1.055e-43
Identity = 88/288 (30.56%), Postives = 165/288 (57.29%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PP++ DLG++A+D+F K Y FGL  +++ ++++        G+ N ++S ++GT ET +    +G+     W+T N L TE++   +  KGLK     SF P+TGKKS   K+SY+R+++N+  ++ +      V+  LVLG      +LAG  + F+     +    FA+GY+  +F + T++ D + F   IYQK+N N +  +++ +   +  +++ IAA+Y I  SD ++   K+N   ++G  Y   +  G++L+LS+ +D K + +G +  GL + +E+
Sbjct:    1 MAVPPTYVDLGKSARDIFTKGYGFGLIKLDLKTRSENGLEFKSSGSANTETSKVAGTLETKYKWAEHGLTFTEKWNTDNTLGTEITLEDQLTKGLKLTFDSSFSPNTGKKSGKIKSSYQREHINLGCDVDYDINGTAVHGALVLGLD---GWLAGYQMTFEAGRNRITQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNDNLETAVNLAWTAGNSNTRFGIAAKYQID-SDAAF-SAKVNNSSLVGLGYTQTLKPGIKLTLSALLDGKNINAGGHKMGLGLEFEA 283

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BLAST of Voltage-dependent anion channel vs. Ensembl Zebrafish
Match: zgc:56235 (zgc:56235 [Source:ZFIN;Acc:ZDB-GENE-040426-954])

HSP 1 Score: 151.754 bits (382), Expect = 5.649e-41
Identity = 89/288 (30.90%), Postives = 160/288 (55.56%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PP++SDLG++AKD+F K Y FG+  +++ +K+         G+ N  +   +G+ ET +   + G+     W+T N+LTTE+S   +  +GLK     SF P+TGKKS   K SYKR+++N++ +L F+   P V+   VLG    + +L G  + FD     L  + FA+GY+  DF + T++ D + F   +YQK++   +  + + +   S  +++ +AA+Y +     + +  K+N   ++G  Y  ++  GV+L+LS+ +D K   +G +  GL    E+
Sbjct:    1 MAVPPAYSDLGKSAKDIFSKGYGFGIVKLDLKTKSQNGVEFNTSGSTNTDTGKAAGSLETKYKLKDLGLSFNQKWNTDNMLTTEVSVEDQLAEGLKVALDTSFVPNTGKKSGKLKTSYKREFVNVSCDLDFEG--PVVHSAAVLGY---EGWLLGYLVAFDTAKSKLVQNNFALGYKTGDFQLHTNVNDGAEFGGSVYQKVSDQLETAVTLAWTAGSNNTRFGVAAKYQLDKD--ASLSAKVNNASLIGIGYTQSLRPGVKLTLSALVDGKNFNTGGHKVGLGFELEA 281

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BLAST of Voltage-dependent anion channel vs. Ensembl Xenopus
Match: vdac2 (voltage-dependent anion channel 2 [Source:NCBI gene;Acc:548947])

HSP 1 Score: 168.318 bits (425), Expect = 9.637e-47
Identity = 92/288 (31.94%), Postives = 164/288 (56.94%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHTTN-YGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PPS++DLG++A+D+F+K Y FGL  ++V +K+ T    A  G+ N  S  ++G+ ET +    YG+     W+T N L TE++   +  KGLK     +F P+TGKKS   K +YKR+Y+N+  ++ F    P ++ + V+G    + +LAG  + FD     L  + FA+GY+  DF + T++ D S F   IYQK++   +  +++ +   +  +++ IAA+Y +     + +  K+N   ++G  Y   +  GV+L+LS+ +D K + +G +  GL +  E+
Sbjct:    1 MAVPPSYADLGKSARDIFNKGYGFGLVKLDVKTKSATGVEFATSGSSNTDSGKVNGSLETKYKWGEYGLTFTEKWNTDNTLGTEIAIEDQIAKGLKLTFDTTFSPNTGKKSGKVKAAYKREYVNLGCDVDFDFAGPAIHGSAVVGY---EGWLAGYQMTFDSAKSKLTKNNFAVGYKTGDFQLHTNVNDGSEFAGSIYQKVSDKMETAVNLAWTSGNNSTRFGIAAKYQL--DSHASISAKVNNSSLVGVGYTQTLRPGVKLTLSALVDGKNINAGGHKLGLGLELEA 283

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BLAST of Voltage-dependent anion channel vs. Ensembl Xenopus
Match: vdac2 (voltage-dependent anion channel 2 [Source:NCBI gene;Acc:548947])

HSP 1 Score: 168.318 bits (425), Expect = 1.019e-46
Identity = 92/288 (31.94%), Postives = 164/288 (56.94%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHTTN-YGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PPS++DLG++A+D+F+K Y FGL  ++V +K+ T    A  G+ N  S  ++G+ ET +    YG+     W+T N L TE++   +  KGLK     +F P+TGKKS   K +YKR+Y+N+  ++ F    P ++ + V+G    + +LAG  + FD     L  + FA+GY+  DF + T++ D S F   IYQK++   +  +++ +   +  +++ IAA+Y +     + +  K+N   ++G  Y   +  GV+L+LS+ +D K + +G +  GL +  E+
Sbjct:    6 MAVPPSYADLGKSARDIFNKGYGFGLVKLDVKTKSATGVEFATSGSSNTDSGKVNGSLETKYKWGEYGLTFTEKWNTDNTLGTEIAIEDQIAKGLKLTFDTTFSPNTGKKSGKVKAAYKREYVNLGCDVDFDFAGPAIHGSAVVGY---EGWLAGYQMTFDSAKSKLTKNNFAVGYKTGDFQLHTNVNDGSEFAGSIYQKVSDKMETAVNLAWTSGNNSTRFGIAAKYQL--DSHASISAKVNNSSLVGVGYTQTLRPGVKLTLSALVDGKNINAGGHKLGLGLELEA 288

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BLAST of Voltage-dependent anion channel vs. Ensembl Xenopus
Match: vdac2 (voltage-dependent anion channel 2 [Source:NCBI gene;Acc:548947])

HSP 1 Score: 168.703 bits (426), Expect = 1.102e-46
Identity = 92/288 (31.94%), Postives = 164/288 (56.94%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHTTN-YGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PPS++DLG++A+D+F+K Y FGL  ++V +K+ T    A  G+ N  S  ++G+ ET +    YG+     W+T N L TE++   +  KGLK     +F P+TGKKS   K +YKR+Y+N+  ++ F    P ++ + V+G    + +LAG  + FD     L  + FA+GY+  DF + T++ D S F   IYQK++   +  +++ +   +  +++ IAA+Y +     + +  K+N   ++G  Y   +  GV+L+LS+ +D K + +G +  GL +  E+
Sbjct:   13 MAVPPSYADLGKSARDIFNKGYGFGLVKLDVKTKSATGVEFATSGSSNTDSGKVNGSLETKYKWGEYGLTFTEKWNTDNTLGTEIAIEDQIAKGLKLTFDTTFSPNTGKKSGKVKAAYKREYVNLGCDVDFDFAGPAIHGSAVVGY---EGWLAGYQMTFDSAKSKLTKNNFAVGYKTGDFQLHTNVNDGSEFAGSIYQKVSDKMETAVNLAWTSGNNSTRFGIAAKYQL--DSHASISAKVNNSSLVGVGYTQTLRPGVKLTLSALVDGKNINAGGHKLGLGLELEA 295

[Close]

BLAST of Voltage-dependent anion channel vs. Ensembl Xenopus
Match: vdac2 (voltage-dependent anion channel 2 [Source:NCBI gene;Acc:548947])

HSP 1 Score: 168.318 bits (425), Expect = 1.835e-46
Identity = 92/288 (31.94%), Postives = 164/288 (56.94%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHTTN-YGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PPS++DLG++A+D+F+K Y FGL  ++V +K+ T    A  G+ N  S  ++G+ ET +    YG+     W+T N L TE++   +  KGLK     +F P+TGKKS   K +YKR+Y+N+  ++ F    P ++ + V+G    + +LAG  + FD     L  + FA+GY+  DF + T++ D S F   IYQK++   +  +++ +   +  +++ IAA+Y +     + +  K+N   ++G  Y   +  GV+L+LS+ +D K + +G +  GL +  E+
Sbjct:   20 MAVPPSYADLGKSARDIFNKGYGFGLVKLDVKTKSATGVEFATSGSSNTDSGKVNGSLETKYKWGEYGLTFTEKWNTDNTLGTEIAIEDQIAKGLKLTFDTTFSPNTGKKSGKVKAAYKREYVNLGCDVDFDFAGPAIHGSAVVGY---EGWLAGYQMTFDSAKSKLTKNNFAVGYKTGDFQLHTNVNDGSEFAGSIYQKVSDKMETAVNLAWTSGNNSTRFGIAAKYQL--DSHASISAKVNNSSLVGVGYTQTLRPGVKLTLSALVDGKNINAGGHKLGLGLELEA 302

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BLAST of Voltage-dependent anion channel vs. Ensembl Xenopus
Match: vdac2 (voltage-dependent anion channel 2 [Source:NCBI gene;Acc:548947])

HSP 1 Score: 168.318 bits (425), Expect = 2.135e-46
Identity = 92/288 (31.94%), Postives = 164/288 (56.94%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHTTN-YGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PPS++DLG++A+D+F+K Y FGL  ++V +K+ T    A  G+ N  S  ++G+ ET +    YG+     W+T N L TE++   +  KGLK     +F P+TGKKS   K +YKR+Y+N+  ++ F    P ++ + V+G    + +LAG  + FD     L  + FA+GY+  DF + T++ D S F   IYQK++   +  +++ +   +  +++ IAA+Y +     + +  K+N   ++G  Y   +  GV+L+LS+ +D K + +G +  GL +  E+
Sbjct:   35 MAVPPSYADLGKSARDIFNKGYGFGLVKLDVKTKSATGVEFATSGSSNTDSGKVNGSLETKYKWGEYGLTFTEKWNTDNTLGTEIAIEDQIAKGLKLTFDTTFSPNTGKKSGKVKAAYKREYVNLGCDVDFDFAGPAIHGSAVVGY---EGWLAGYQMTFDSAKSKLTKNNFAVGYKTGDFQLHTNVNDGSEFAGSIYQKVSDKMETAVNLAWTSGNNSTRFGIAAKYQL--DSHASISAKVNNSSLVGVGYTQTLRPGVKLTLSALVDGKNINAGGHKLGLGLELEA 317

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BLAST of Voltage-dependent anion channel vs. Ensembl Mouse
Match: Vdac1 (voltage-dependent anion channel 1 [Source:MGI Symbol;Acc:MGI:106919])

HSP 1 Score: 166.007 bits (419), Expect = 7.277e-46
Identity = 86/290 (29.66%), Postives = 167/290 (57.59%), Query Frame = 3

Query:   99 QHVMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            Q++ +PP+++DLG++A+D+F K Y FGL  +++ +K++        G+ N +++ ++G+ ET +  T YG+     W+T N L TE++   +  +GLK     SF P+TGKK+   K  YKR+++N+  ++ F    P +   LVLG    + +LAG  +NF+ +   +    FA+GY+  +F + T++ D + F   IYQK+NK  +  +++ +   +  +++ IAA+Y +     +    K+N   ++G  Y   +  G++L+LS+ +D K + +G +  GL + +++
Sbjct:   12 QNMAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGY---EGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQVDPD--ACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA 296

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BLAST of Voltage-dependent anion channel vs. Ensembl Mouse
Match: Vdac1 (voltage-dependent anion channel 1 [Source:MGI Symbol;Acc:MGI:106919])

HSP 1 Score: 164.081 bits (414), Expect = 2.707e-45
Identity = 85/288 (29.51%), Postives = 165/288 (57.29%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PP+++DLG++A+D+F K Y FGL  +++ +K++        G+ N +++ ++G+ ET +  T YG+     W+T N L TE++   +  +GLK     SF P+TGKK+   K  YKR+++N+  ++ F    P +   LVLG    + +LAG  +NF+ +   +    FA+GY+  +F + T++ D + F   IYQK+NK  +  +++ +   +  +++ IAA+Y +     +    K+N   ++G  Y   +  G++L+LS+ +D K + +G +  GL + +++
Sbjct:    1 MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGY---EGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQVDPD--ACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA 283

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BLAST of Voltage-dependent anion channel vs. Ensembl Mouse
Match: Vdac2 (voltage-dependent anion channel 2 [Source:MGI Symbol;Acc:MGI:106915])

HSP 1 Score: 162.54 bits (410), Expect = 8.878e-45
Identity = 89/288 (30.90%), Postives = 162/288 (56.25%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + IPP ++DLG+AA+D+F+K + FGL  ++V +K+ +    +  G+ N  +  +SGT ET +    YG+     W+T N L TE++   +  +GLK     +F P+TGKKS   K++YKR+ +N+  ++ F    P ++ + V G    + +LAG  + FD     L    FA+GY   DF + T++ + + F   IYQK+ ++ D  +++ +   +  +++ IAA+Y +  +  + +  K+N   ++G  Y   +  GV+L+LS+ +D K   +G +  GLA+  E+
Sbjct:    1 MCIPPPYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVSGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSAYKRECINLGCDVDFDFAGPAIHGSAVFG---YEGWLAGYQMTFDSAKSKLTRSNFAVGYRTGDFQLHTNVNNGTEFGGSIYQKVCEDFDTSVNLAWTSGTNCTRFGIAAKYQLDPT--ASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSFNAGGHKLGLALELEA 283

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Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + IPP ++DLG+AA+D+F+K + FGL  ++V +K+ +    +  G+ N  +  +SGT ET +    YG+     W+T N L TE++   +  +GLK     +F P+TGKKS   K++YKR+ +N+  ++ F    P ++ + V G    + +LAG  + FD     L    FA+GY   DF + T++ + + F   IYQK+ ++ D  +++ +   +  +++ IAA+Y +  +  + +  K+N   ++G  Y   +  GV+L+LS+ +D K   +G +  GLA+  E+
Sbjct:    1 MCIPPPYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVSGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSAYKRECINLGCDVDFDFAGPAIHGSAVFG---YEGWLAGYQMTFDSAKSKLTRSNFAVGYRTGDFQLHTNVNNGTEFGGSIYQKVCEDFDTSVNLAWTSGTNCTRFGIAAKYQLDPT--ASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSFNAGGHKLGLALELEA 283

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BLAST of Voltage-dependent anion channel vs. Ensembl Mouse
Match: Vdac2 (voltage-dependent anion channel 2 [Source:MGI Symbol;Acc:MGI:106915])

HSP 1 Score: 162.54 bits (410), Expect = 1.162e-44
Identity = 89/290 (30.69%), Postives = 163/290 (56.21%), Query Frame = 3

Query:   99 QHVMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + + IPP ++DLG+AA+D+F+K + FGL  ++V +K+ +    +  G+ N  +  +SGT ET +    YG+     W+T N L TE++   +  +GLK     +F P+TGKKS   K++YKR+ +N+  ++ F    P ++ + V G    + +LAG  + FD     L    FA+GY   DF + T++ + + F   IYQK+ ++ D  +++ +   +  +++ IAA+Y +  +  + +  K+N   ++G  Y   +  GV+L+LS+ +D K   +G +  GLA+  E+
Sbjct:   11 RPMCIPPPYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVSGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSAYKRECINLGCDVDFDFAGPAIHGSAVFG---YEGWLAGYQMTFDSAKSKLTRSNFAVGYRTGDFQLHTNVNNGTEFGGSIYQKVCEDFDTSVNLAWTSGTNCTRFGIAAKYQLDPT--ASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSFNAGGHKLGLALELEA 295

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BLAST of Voltage-dependent anion channel vs. UniProt/SwissProt
Match: sp|P68002|VDAC2_BOVIN (Voltage-dependent anion-selective channel protein 2 OS=Bos taurus OX=9913 GN=VDAC2 PE=2 SV=2)

HSP 1 Score: 167.933 bits (424), Expect = 9.225e-46
Identity = 91/290 (31.38%), Postives = 166/290 (57.24%), Query Frame = 3

Query:   99 QHVMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + + IPPS++DLG+AA+D+F+K + FGL  ++V +K+ +    +  G+ N  +  ++GT ET +    YG+     W+T N L TE++   +  +GLK     +F P+TGKKS   K+SYKR+ +N+  ++ F    P ++ + V G    + +LAG  + FD     L  + FA+GY   DF + T++ D + F   IYQK+ ++ D  +++ +   +  +++ IAA+Y +  +  + +  K+N   ++G  Y   +  GV+L+LS+ +D K + +G +  GLA+  E+
Sbjct:   10 RPMCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSSYKRECINLGCDVDFDFAGPAIHGSAVFG---YEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQLHTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDPT--ASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKLGLALELEA 294

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BLAST of Voltage-dependent anion channel vs. UniProt/SwissProt
Match: sp|P68003|VDAC2_RABIT (Voltage-dependent anion-selective channel protein 2 OS=Oryctolagus cuniculus OX=9986 GN=VDAC2 PE=2 SV=1)

HSP 1 Score: 167.933 bits (424), Expect = 1.010e-45
Identity = 91/290 (31.38%), Postives = 166/290 (57.24%), Query Frame = 3

Query:   99 QHVMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + + IPPS++DLG+AA+D+F+K + FGL  ++V +K+ +    +  G+ N  +  ++GT ET +    YG+     W+T N L TE++   +  +GLK     +F P+TGKKS   K+SYKR+ +N+  ++ F    P ++ + V G    + +LAG  + FD     L  + FA+GY   DF + T++ D + F   IYQK+ ++ D  +++ +   +  +++ IAA+Y +  +  + +  K+N   ++G  Y   +  GV+L+LS+ +D K + +G +  GLA+  E+
Sbjct:   10 RPMCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSSYKRECINLGCDVDFDFAGPAIHGSAVFG---YEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQLHTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDPT--ASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKLGLALELEA 294

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BLAST of Voltage-dependent anion channel vs. UniProt/SwissProt
Match: sp|Q9MZ15|VDAC2_PIG (Voltage-dependent anion-selective channel protein 2 OS=Sus scrofa OX=9823 GN=VDAC2 PE=2 SV=1)

HSP 1 Score: 167.548 bits (423), Expect = 1.354e-45
Identity = 91/290 (31.38%), Postives = 166/290 (57.24%), Query Frame = 3

Query:   99 QHVMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + + IPPS++DLG+AA+D+F+K + FGL  ++V +K+ +    +  G+ N  +  ++GT ET +    YG+     W+T N L TE++   +  +GLK     +F P+TGKKS   K+SYKR+ +N+  ++ F    P ++ + V G    + +LAG  + FD     L  + FA+GY   DF + T++ D + F   IYQK+ ++ D  +++ +   +  +++ IAA+Y +  +  + +  K+N   ++G  Y   +  GV+L+LS+ +D K + +G +  GLA+  E+
Sbjct:   10 RPMCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSSYKRECVNLGCDVDFDFAGPAIHGSAVFG---YEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQLHTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDPT--ASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKLGLALELEA 294

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BLAST of Voltage-dependent anion channel vs. UniProt/SwissProt
Match: sp|P45880|VDAC2_HUMAN (Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2)

HSP 1 Score: 167.548 bits (423), Expect = 1.483e-45
Identity = 91/290 (31.38%), Postives = 166/290 (57.24%), Query Frame = 3

Query:   99 QHVMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + + IPPS++DLG+AA+D+F+K + FGL  ++V +K+ +    +  G+ N  +  ++GT ET +    YG+     W+T N L TE++   +  +GLK     +F P+TGKKS   K+SYKR+ +N+  ++ F    P ++ + V G    + +LAG  + FD     L  + FA+GY   DF + T++ D + F   IYQK+ ++ D  +++ +   +  +++ IAA+Y +  +  + +  K+N   ++G  Y   +  GV+L+LS+ +D K + +G +  GLA+  E+
Sbjct:   10 RPMCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSSYKRECINLGCDVDFDFAGPAIHGSAVFG---YEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQLHTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDPT--ASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVGLALELEA 294

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BLAST of Voltage-dependent anion channel vs. UniProt/SwissProt
Match: sp|P82013|VDAC2_MELGA (Voltage-dependent anion-selective channel protein 2 OS=Meleagris gallopavo OX=9103 GN=VDAC2 PE=1 SV=1)

HSP 1 Score: 166.007 bits (419), Expect = 3.353e-45
Identity = 92/286 (32.17%), Postives = 163/286 (56.99%), Query Frame = 3

Query:  111 IPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            IPPS++DLG++A+D+F+K Y FGL  ++V +K+ +       G+ N  +  ++G+ ET +    YG+     W+T N L TE++   +  KGLK     +F P+TGKKS   K++YKR+ LN+  ++ F    P ++ + V G    + +LAG  + FD     L  + F++GY+  DF + T++ D S F   IYQK++ N +  +++ +   S  +++ IAA+Y +  +  + +  K+N   ++G  Y   +  GV+L+LS+ ID K + +G +  GL +  E+
Sbjct:    2 IPPSYADLGKSARDIFNKGYGFGLVKLDVKTKSASGVEFTTSGSSNTDTGKVNGSLETKYKWAEYGLTFTEKWNTDNTLGTEIAIEDQIAKGLKLTFDTTFSPNTGKKSGKIKSAYKRECLNLGCDVDFDFAGPAIHGSAVFGY---EGWLAGYQMTFDSAKSKLTRNNFSVGYKTGDFQLHTNVNDGSEFGGSIYQKVSDNLETAVNLAWTAGSNSTRFGIAAKYKLDST--ASISAKVNNSSLVGVGYTQTLRPGVKLTLSALIDGKSINAGGHKLGLGLELEA 282

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BLAST of Voltage-dependent anion channel vs. TrEMBL
Match: A0A1S3IT01 (voltage-dependent anion-selective channel protein 2 OS=Lingula unguis OX=7574 GN=LOC106167163 PE=4 SV=1)

HSP 1 Score: 184.496 bits (467), Expect = 1.483e-49
Identity = 103/285 (36.14%), Postives = 167/285 (58.60%), Query Frame = 3

Query:  111 IPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDT-ASVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYE 959
            +PP F+DLG+ A+D+F KKY FG + +E  +K  +     ++G+ N  + ++ GTFET +   + GI +K  W+T N+L+T+++   + ++GLK     SF P +GKKS   K +YKRDY+N+N ++      P V+   VLG S    +LAG  ++FD  N  L  +TFA GY+K DF I T++ D S F   +YQKI+K+ +  + + ++  +  ++  + A Y + +  +  V+ K+N    +G  Y   + DGV L+LSS IDAK   SG +  GL + +E
Sbjct:    3 VPPCFADLGKDARDVFSKKYNFGFFKIETSTKTKSNVEFKVEGSSNHDTGNVFGTFETKYKWADPGITVKEKWNTDNMLSTDITIEDQLLEGLKLTLDGSFAPVSGKKSAKIKAAYKRDYINLNCDVDLGFAGPTVHGAAVLGYS---GWLAGAQISFDTANSKLVKNTFAAGYKKDDFQIHTTVTDASEFGGSLYQKISKDLETAVSLNWSSGTNTTRLNLGAAYTLDNGAK--VRAKVNNLSQIGMAYSQELRDGVTLNLSSMIDAKNFNSGGHKVGLGLEFE 282

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BLAST of Voltage-dependent anion channel vs. TrEMBL
Match: R7VH43 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_148920 PE=4 SV=1)

HSP 1 Score: 184.496 bits (467), Expect = 3.867e-49
Identity = 100/289 (34.60%), Postives = 165/289 (57.09%), Query Frame = 3

Query:  102 HVMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSK-NDTASVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            H+ IPP+++DLG+ A+DLF K + +G Y +EV ++ ++  +    GN N  S  + G  ET +  ++YG+     W+T NVL TE++   + +KGLK     SF P TGKKS   K +YK+DY+N   ++ F    P +N  +VLG    + +LAG  + FD +   L    FA+GY   DF + TS+ D S F   ++QK+N++ + G+ + +   S  +K+ +AA+Y  P  D + ++ K+N +  +G  Y   I DGV L+LS+ ++ K    G +  GL + +E+
Sbjct:   25 HMTIPPTYADLGKGARDLFSKGFNYGTYKLEVKTQTSNGVNFTTSGNSNHDSGKVGGNLETKYKYSDYGLTFVEKWNTDNVLGTEITIEDQMLKGLKLSFDTSFAPQTGKKSGKIKTAYKQDYVNAGCDVDFDFAGPTINGAMVLGY---QGWLAGYQMAFDTSKSKLAKSNFAVGYTTGDFTLHTSVNDGSDFTGAVFQKVNRDLEAGVQLNWTAGSNATKFGLAAKY-TPDRDTT-IRAKVNNNSQIGLAYQQKIRDGVSLTLSTLLEGKNFNQGGHKVGLGLDFEA 308

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BLAST of Voltage-dependent anion channel vs. TrEMBL
Match: A0A401NLF2 (Uncharacterized protein OS=Scyliorhinus torazame OX=75743 GN=scyTo_0011357 PE=4 SV=1)

HSP 1 Score: 179.104 bits (453), Expect = 5.567e-47
Identity = 95/290 (32.76%), Postives = 169/290 (58.28%), Query Frame = 3

Query:   99 QHVMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + + +PPS++DLG+AA+D+F+K Y FGL  +EV +K+ +       G+ N +S  +SG+ ET +  + YG+     W+T N L TE++   +  KGLK     +F P+TGKKS   K +YKR+Y+N+  ++ F    P ++ + V G    + +LAG  ++FD     L  + FA+GY+  DF + T++ D + F   IYQK+++N +  +++T+   +  +++ IAA+Y +  +  + +  K+N   ++G  Y   +  G++L+L S ID K + SG +  GL +  E+
Sbjct:   45 ERMAVPPSYADLGKAARDIFNKGYAFGLIKLEVKTKSQSGVEFTTSGSSNTESGKVSGSLETKYKWSEYGLTFTEKWNTDNTLGTEIAIEDQLAKGLKLTFDTTFSPNTGKKSGRVKTAYKREYVNLGCDVDFDFAGPAIHASAVAGY---EGWLAGYQMSFDTAKSKLTQNNFAVGYKTGDFQLHTNVNDGAEFGGSIYQKVSENLETAVNLTWTAGNNSTRFGIAAKYQLDPT--ASISAKVNNSSLIGIGYSQILRPGIKLTLCSLIDGKSINSGGHKLGLGLELEA 329

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BLAST of Voltage-dependent anion channel vs. TrEMBL
Match: A0A2G8LNP3 (Putative voltage-dependent anion-selective channel protein 2-like OS=Stichopus japonicus OX=307972 GN=BSL78_01210 PE=4 SV=1)

HSP 1 Score: 176.792 bits (447), Expect = 1.295e-46
Identity = 101/284 (35.56%), Postives = 156/284 (54.93%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAI 950
            + IPP +SDLG+AA+DLF K Y FG   +++ +K        I G+ N  S  + G+ ET +   +YG+  K  W+T N L  E+S   +   GLK     SF P+TGKK+   K  YKRDY+N+N+++ F+   P +N   VLG    + +LAG    FD +   L  + FA+GY+  DF +  S+ D S F   +YQK+N N +   ++ +   S  +++ + A+Y +   D S+   KI+    +G  Y  ++ DGV+L+LSS ID K L  G +  GL +
Sbjct:    1 MAIPPGYSDLGKAARDLFSKGYGFGFAKLDISTKTSAGVEFTIGGSSNNDSGKVDGSLETKYAWKDYGLSFKEKWNTDNTLCAEVSIEDQIASGLKLTFDTSFAPNTGKKTGQVKTVYKRDYMNVNADVDFEFAGPTINGAAVLGY---EGWLAGYQFAFDSSKSKLTKNNFALGYKTDDFQLHASVNDGSDFCGSVYQKVNDNLETAFNLGWTSGSNATRFAVGAKYTVDK-DSSF-SAKISNTSQLGLGYSHSLRDGVKLTLSSLIDGKNLNQGGHKLGLGL 279

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BLAST of Voltage-dependent anion channel vs. TrEMBL
Match: A0A401T5U1 (Uncharacterized protein OS=Chiloscyllium punctatum OX=137246 GN=chiPu_0016503 PE=4 SV=1)

HSP 1 Score: 177.178 bits (448), Expect = 4.117e-46
Identity = 94/289 (32.53%), Postives = 166/289 (57.44%), Query Frame = 3

Query:  102 HVMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
             + +PPS++DLG+AA+D+F+K Y FGL  +EV +K+ +       G+ N +S  +SG+ ET +  + YG+     W+T N L TE++   +  KGLK     +F P+TGKKS   K +YKR+Y+N+  ++ F    P ++ + V G    + +LAG  ++FD     L  + FA+GY+  DF + T++ D + F   IYQK++ N D  +++ +   +  +++ IAA+Y +  +  + +  K+N   ++G  Y   +  G++L+L + ID K + SG +  GL +  E+
Sbjct:   57 RMAVPPSYADLGKAARDIFNKGYGFGLIKLEVKTKSQSGVEFTTSGSSNTESGKVSGSLETKYKWSEYGLTFTEKWNTDNTLGTEIAIEDQLAKGLKLTFDTTFSPNTGKKSGRVKTAYKREYINLGCDVDFDFAGPAIHASAVAGY---EGWLAGYQMSFDTAKSKLTQNNFAVGYKTGDFQLHTNVNDGAEFGGSIYQKVSDNLDTAVNLAWTAGNNSTRFGIAAKYQLDST--ASISAKVNNSSLIGIGYSQILRPGIKLTLCTLIDGKSINSGGHKLGLGLELEA 340

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BLAST of Voltage-dependent anion channel vs. Ensembl Cavefish
Match: VDAC2 (voltage-dependent anion-selective channel protein 2 [Source:NCBI gene;Acc:103040512])

HSP 1 Score: 169.474 bits (428), Expect = 1.846e-47
Identity = 93/284 (32.75%), Postives = 162/284 (57.04%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKN-DTASVAIKGNHNIKSSSLSGTFETTHTTN-YGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAI 950
            + +PP+++DLG++AKD+F+K Y FGL  ++V +K+ +       G+ N  ++ ++G  ET +  + YG+     W+T N L TE++   +  KGLK     +F P+TGKKS   K +YKR++LN+  ++ F    P V+   VLG    + +LAG  + FD     +  + FAIGY+  DF + T++ D S F   IYQK+N   +  +++ +   +  +++ IAA+Y +  S  S +  K+N   ++G  Y   +  GV+L+LS+ +D K + +G +  GL +
Sbjct:    1 MAVPPAYADLGKSAKDIFNKGYGFGLVKLDVKTKSANGVEFKTSGSSNTDTNKVTGNLETKYKWDEYGLTFTEKWNTDNTLGTEITVEDQITKGLKLTFDTTFSPNTGKKSGKVKTAYKREFLNVGCDVDFDFAGPAVHGAAVLGF---EGWLAGYQMTFDTAKSKMTRNNFAIGYKTGDFQLHTNVNDGSEFGGSIYQKVNDELETAVNLAWTAGNNSTRFGIAAKYQLDSS--SSISAKVNNSSLVGVGYTQTLRPGVKLTLSALVDGKSINAGGHKLGLGL 279

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BLAST of Voltage-dependent anion channel vs. Ensembl Cavefish
Match: vdac3 (voltage dependent anion channel 3 [Source:NCBI gene;Acc:103039704])

HSP 1 Score: 167.548 bits (423), Expect = 1.163e-46
Identity = 95/287 (33.10%), Postives = 158/287 (55.05%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHTT-NYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYE 959
            + +PP+++DLG++AKD+F K Y FG   +++ +K+ +    +  G+ N  +   SG  ET +   + G++    W+T N LTTE+S   +  KGLK     SF P+TGKKS   K  YKR+Y+N+  ++ F    P V+   VLG    + +LAG  + FD     L  + FA+GY+  DF + T++ D + F   IYQK+N   +  +++ +   S  +++ IAA+Y +     + V  K+N   ++G  Y   +  GV+L+LS+ IDAK   +G +  G+    E
Sbjct:    1 MAVPPAYADLGKSAKDIFSKGYGFGTVKLDLKTKSQSGVEFSTGGSSNTDTGKASGNLETKYKVKDLGLNFNQKWNTDNTLTTEISMEDQLAKGLKLGLDTSFVPNTGKKSAKLKTGYKREYMNVGCDIDFDLAGPTVHAAAVLGY---EGWLAGYQMAFDTAKSKLAQNNFALGYKAGDFQLHTNVNDGTEFGGSIYQKVNSELETAVNLAWTAGSNNTRFGIAAKYQLDKD--ASVSAKVNNASLVGVGYTQALRPGVKLTLSALIDAKNFNAGGHKVGMGFELE 282

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BLAST of Voltage-dependent anion channel vs. Ensembl Cavefish
Match: vdac2 (voltage-dependent anion-selective channel protein 2 [Source:NCBI gene;Acc:103037680])

HSP 1 Score: 167.162 bits (422), Expect = 1.287e-46
Identity = 90/288 (31.25%), Postives = 164/288 (56.94%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTH-TTNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PP ++DLG++AKD+F+K Y FGL  ++V +K+ +       G+ N  +S + G+ ET +  + YG+     W+T N L TE++   +  KGLK     +F P+TGKKS   K +YKR+++N+  ++ F    P ++   V+G    + +LAG  ++FD     +  + FA+GY+  DF + T++ D S F   IYQK++ N +  +++ +   S  +++ IAA+Y +     + +  K+N   ++G  Y   +  GV+L+LS+ +D K + +G +  GL +  E+
Sbjct:    1 MAVPPCYADLGKSAKDIFNKGYGFGLVKLDVKTKSSSGVEFKTSGSSNTDTSKVVGSLETKYKRSEYGLTFTEKWNTDNTLGTEITIEDQIAKGLKLTFDTTFSPNTGKKSGKVKTAYKREFVNLGCDVDFDFAGPTIHGAAVVGY---EGWLAGYQMSFDTAKSKMTQNNFAVGYKTGDFQLHTNVNDGSEFGGSIYQKVSDNLETAVNLAWTAGSNSTRFGIAAKYQLDKD--ASISAKVNNTSLVGVGYTQTLRPGVKLTLSALVDGKSINAGGHKLGLGLELEA 283

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BLAST of Voltage-dependent anion channel vs. Ensembl Cavefish
Match: vdac1 (voltage dependent anion channel 1 [Source:NCBI gene;Acc:103024199])

HSP 1 Score: 152.525 bits (384), Expect = 3.065e-41
Identity = 88/290 (30.34%), Postives = 161/290 (55.52%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYP--KPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PP++ DLG++AKD+F K Y FGL  +++ +K++        G+ N ++S +SG  ET +    +G+     W+T N L TE++   +  KGLK     SF P+TGKKS   K+ YKR+++N+  ++ +     D+N   V G      + +LAG  + F+     +    FA+GY+  +F + T++ D + F   IYQK+N   +  +++ +   +  +++ IAA+Y I  +D S+   K+N   ++G  Y   +  G++L+LS+ +D K + +G +  GL +  E+
Sbjct:    1 MAVPPTYVDLGKSAKDVFTKGYGFGLIKLDLKTKSENGLEFKSAGSANTETSKVSGALETKYKWAEHGLTFTEKWNTDNTLGTEITLEDQLAKGLKLTFDSSFSPNTGKKSGKIKSGYKREHINLGCDVDY-----DINGTAVHGAVVVGYEGWLAGYQMTFEAGKNRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNDKLETAVNLAWTAGNSNTRFGIAAKYQID-ADASF-SAKVNNSSLVGLGYTQTLKPGIKLTLSALLDGKNINAGGHKLGLGLELEA 283

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BLAST of Voltage-dependent anion channel vs. Ensembl Cavefish
Match: vdac3 (voltage dependent anion channel 3 [Source:NCBI gene;Acc:103039704])

HSP 1 Score: 148.288 bits (373), Expect = 7.876e-39
Identity = 84/256 (32.81%), Postives = 140/256 (54.69%), Query Frame = 3

Query:   93 KTQHVMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHTT-NYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVY 854
            K   + +PP+++DLG++AKD+F K Y FG   +++ +K+ +    +  G+ N  +   SG  ET +   + G++    W+T N LTTE+S   +  KGLK     SF P+TGKKS   K  YKR+Y+N+  ++ F    P V+   VLG    + +LAG  + FD     L  + FA+GY+  DF + T++ D + F   IYQK+N   +  +++ +   S  +++ IAA+Y +     + V  K+N   ++G  Y
Sbjct:   74 KCASMAVPPAYADLGKSAKDIFSKGYGFGTVKLDLKTKSQSGVEFSTGGSSNTDTGKASGNLETKYKVKDLGLNFNQKWNTDNTLTTEISMEDQLAKGLKLGLDTSFVPNTGKKSAKLKTGYKREYMNVGCDIDFDLAGPTVHAAAVLGY---EGWLAGYQMAFDTAKSKLAQNNFALGYKAGDFQLHTNVNDGTEFGGSIYQKVNSELETAVNLAWTAGSNNTRFGIAAKYQLDKD--ASVSAKVNNASLVGVGY 324

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BLAST of Voltage-dependent anion channel vs. Ensembl Sea Lamprey
Match: vdac2 (voltage-dependent anion channel 2 [Source:ZFIN;Acc:ZDB-GENE-030131-845])

HSP 1 Score: 170.244 bits (430), Expect = 2.302e-48
Identity = 94/288 (32.64%), Postives = 163/288 (56.60%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PP+F DLG++A+D+F K + FGL  +++ +K  +    +  G+ N ++  ++ + ET +   +YG+++   WST N L TE+S   +  KGLK     +F P+TGKKS   K++YKR+YLN+  ++      P VN   V+G    + +LAG  L FD     L    FAIGY+ +DF + T++ D + F   IYQK+N   +  + + +   S  +++ IAA+Y +  +  + +  K+N   ++G  Y   +  GV+LSLS+ +D K + +G +  GL +  E+
Sbjct:    1 MAVPPTFVDLGKSARDVFSKGFGFGLVKLDLKTKTSSGVEFSTSGSSNSETGKVNASLETKYKWADYGLNLTEKWSTDNTLATEISVEDQLAKGLKLTLDTTFAPNTGKKSGKLKSTYKREYLNLGCDVDLDFAGPTVNGAAVVGY---EGWLAGYQLAFDTAKSKLTRSNFAIGYKTADFQLHTNVNDGTEFGGNIYQKVNDKLETAVDLAWTAGSNTTRFGIAAKYQLDSN--TTINAKVNNSSLVGLGYTQTLRPGVKLSLSALLDGKNINAGGHKLGLGLELEA 283

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BLAST of Voltage-dependent anion channel vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005399.1 (pep scaffold:Pmarinus_7.0:GL479471:12985:19564:-1 gene:ENSPMAG00000004891.1 transcript:ENSPMAT00000005399.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 130.954 bits (328), Expect = 2.415e-34
Identity = 78/285 (27.37%), Postives = 146/285 (51.23%), Query Frame = 3

Query:  114 PPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            PP F  LG AA+++F K Y FGL  ++  ++  +      +G  +  S  +SG  ET ++   +G+ +   WST N L T +S   +  KGL+ V   SF P+TGKK+   K  Y R +++  +++      P V  ++VL     + +LAG  +  D+  + + ++  ++GY   DF + T++ D   F+   +Q++++  D  + + ++  +   ++ +   Y I  +  + V GK+N   ++G  Y   +  GV+LSL   +D K + SG +  GL +  E+
Sbjct:    4 PPFFESLGEAAREVFTKGYGFGLVKLDFTTRAASGVEFNTRGASHTDSGRVSGALETRYSWPEHGLRLVECWSTDNCLGTRISVDDQLAKGLQLVFDTSFSPNTGKKTGLVKVLYARPFVSATTDVDVSLGGPIVASSVVLAA---RGWLAGYHMGLDVGKRKITSNRISLGYMTEDFQLLTNVVDGVEFSGSYFQRVSERLDTAVRLAWSAGAPHPRFTLGGTYKIDQN--ASVSGKMNSASLLGLSYTQALRPGVKLSLCGLLDVKNINSGGHKLGLGLELEA 283

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BLAST of Voltage-dependent anion channel vs. Ensembl Yeast
Match: POR1 (Mitochondrial porin (voltage-dependent anion channel); outer membrane protein required for maintenance of mitochondrial osmotic stability and mitochondrial membrane permeability; couples the glutathione pools of the intermembrane space (IMS) and the cytosol; interacts with Om45 and Om14 in the outer membrane; phosphorylated; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005000])

HSP 1 Score: 65.0846 bits (157), Expect = 4.540e-12
Identity = 64/292 (21.92%), Postives = 120/292 (41.10%), Query Frame = 3

Query:  108 MIPPSFSDLGRAAKDLFDKKY---KFGLYNVEVCSKNDTASVAIKGNHNIKSSSLSGTFET-THTTNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYN---KNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            M PP +SD+ R   DL +K +       ++V+  + N     ++K    +K   LS   E   +    G+ +   WS  N L T+L +      GLK   I S  P   K ++    ++ + +             P    +L +     +  + G +  +DI+   +  +  A+ Y   D+ +  ++ +  +     +Q +N    +G   T N    NS ++  E A +Y+   S  S VK K++   I+   Y   +  GV L + S  DA KL    +  G ++ +++
Sbjct:    1 MSPPVYSDISRNINDLLNKDFYHATPAAFDVQTTTANGI-KFSLKAKQPVKDGPLSTNVEAKLNDKQTGLGLTQGWSNTNNLQTKL-EFANLTPGLKNELITSLTPGVAKSAV-LNTTFTQPFFTARGAFDLCLKSPTFVGDLTMAH---EGIVGGAEFGYDISAGSISRYAMALSYFAKDYSLGATLNNEQITTVDFFQNVNAFLQVGAKATMNCKLPNSNVN-IEFATRYLPDAS--SQVKAKVSDSGIVTLAYKQLLRPGVTLGVGSSFDALKLSEPVHKLGWSLSFDA 283

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BLAST of Voltage-dependent anion channel vs. Ensembl Nematostella
Match: EDO31835 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWS9])

HSP 1 Score: 141.354 bits (355), Expect = 1.037e-37
Identity = 83/285 (29.12%), Postives = 151/285 (52.98%), Query Frame = 3

Query:  114 PPSFSDLGRAAKDLFDKKYKFGLYNVEV-CSKNDTASVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            P  + DLG+ A+D+F K Y FG   V++  +  +       G+    +  + G+ ET +  ++YGI +   W+T NVL++E++   +  KGLK     +F P+TGKKS   K +YK+DYL+   ++ F    P V  + V+G    + + AG  + +D +   L  + F++GY   DF I +++ D S F   IY +I+KN ++   + +   S  + ++   +Y +     + ++ K+N +  +G  Y   + DG++ ++SS ID K L  G +  GL++  E+
Sbjct:    5 PVKYEDLGKEARDVFGKGYGFGCVKVDLKTTTKNGVEFKTAGSSMNDTGKVFGSLETKYKYSDYGISLSEKWTTDNVLSSEITVEDQIAKGLKLQFDTTFAPNTGKKSAKIKTAYKQDYLHATGDVDFDFAGPTVQGSAVVGY---EGWHAGYQVAYDTSKSKLIANNFSLGYRAKDFQIHSAVNDASKFTGSIYHQISKNLEVAAQLNWATGSSNTSFQGGCKYDVDKD--TTLRAKVNNNSHLGLAYTQRLRDGIKATVSSHIDTKNLNQGGHKLGLSLEMEA 284

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BLAST of Voltage-dependent anion channel vs. Ensembl Medaka
Match: vdac2 (voltage-dependent anion-selective channel protein 2 [Source:NCBI gene;Acc:101173732])

HSP 1 Score: 169.859 bits (429), Expect = 1.592e-47
Identity = 92/288 (31.94%), Postives = 163/288 (56.60%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTH-TTNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PP+++DLG++AKD+FDK Y FG+  ++V +K+ +       G+ N  +S +SGT ET +    YG+     W+T N L TE++   +  KGLK     +F P+TGKKS   K +YKR+Y+N+  ++ F    P ++ N V+G    + +LAG  ++FD     +  + FAIGY+  DF + T++ D S F   IYQK++   +  + + +   S  +++ I A+Y +     + +  K+N + ++G  Y   +  GV+L+L+  +D K + +G +  GL +  E+
Sbjct:    1 MAVPPAYADLGKSAKDIFDKGYGFGVVKLDVKTKSASGVEFKTSGSSNTDTSKVSGTLETKYKRAEYGLTFTEKWNTDNTLGTEITIEDQIAKGLKLTFDTTFSPNTGKKSGKVKAAYKREYVNLGCDVDFDFAGPTIHGNGVVGY---EGWLAGYQMSFDTAKSKMIRNNFAIGYKTGDFQLHTNVNDGSEFGGSIYQKVSDKLETAVSLAWTAGSNSTRFGIGAKYQLDKD--ASISAKVNNNSLVGVGYTQTLRPGVKLTLAGLVDGKSINAGGHKLGLGLELEA 283

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BLAST of Voltage-dependent anion channel vs. Ensembl Medaka
Match: vdac3 (voltage-dependent anion-selective channel protein 2 [Source:NCBI gene;Acc:101170932])

HSP 1 Score: 167.933 bits (424), Expect = 2.259e-46
Identity = 95/288 (32.99%), Postives = 158/288 (54.86%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHTTN-YGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PP++SDLG++AKD+F+K + +G+  +++ +K+ +    A  G++N  +    G  ET +  N  G+     W+T N LTTE++   +  KGLK     SF P+TGKKS   K  YKR+Y+N+  +L F    P V+   VLG    + +LAG  L FD     L  + FA+GY+  DF + T + D + F   IYQK+N + +  +H+ +   S  +++ I A+Y +     + +  K+N   ++G  Y   +  GV+L+LS+ ID K +  G +  GL    E+
Sbjct:   40 MAVPPAYSDLGKSAKDIFNKGFGYGVLKLDIKTKSQSGVEFATSGSNNTDTGKSGGHLETKYKLNELGLSFNQKWNTDNTLTTEITMEDQLAKGLKLGLDSSFVPNTGKKSAKLKTGYKREYMNLGCDLDFDMAGPTVHAAAVLGY---EGWLAGYQLAFDTAKSKLAQNNFALGYKAGDFQLHTHVNDGTEFGGSIYQKVNNSLETAVHLAWTAGSNNTRFGIGAKYQLDKD--ASLSTKVNNACLVGVGYTHTLRPGVKLTLSAMIDGKNVNGGGHKVGLGFELEA 322

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BLAST of Voltage-dependent anion channel vs. Ensembl Medaka
Match: VDAC2 (voltage-dependent anion-selective channel protein 2 [Source:NCBI gene;Acc:101154906])

HSP 1 Score: 156.377 bits (394), Expect = 1.263e-42
Identity = 89/288 (30.90%), Postives = 157/288 (54.51%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PP+++DLG++AKD+F K Y FGL  ++V +K+ +       G+ N  +S ++GT ET +    YG+     WST+N L TE+    +  KGLK     +F P+TGKKS   K +YK++++N   ++      P ++   V G    + +LAG  + FD     +    FA+GY   DF + T++ D + F   IYQK+N   +  +++ +   S  + + IAA+Y +  S  + +  K+N   ++G  Y   +  G++L+LS+ +D K + +G +  GL +  E+
Sbjct:    1 MTVPPAYADLGKSAKDIFSKGYGFGLVKLDVKTKSSSGVEFKTSGSSNTDTSKVTGTLETKYKLPEYGLTFTEKWSTENTLGTEVCVEDQITKGLKLNFDTTFSPNTGKKSGKIKAAYKKEHVNAGVDVDLDFAGPTIHAAAVGGY---EGWLAGYQMTFDSAKSRMTRSNFAVGYTTGDFQLHTNVNDGAEFGGSIYQKVNDKLETAVNLAWTVGSNGTLFGIAAKYQLDPS--ASISAKVNNASLVGIGYTQTLRPGMKLTLSAMVDGKNINAGGHKLGLGLELEA 283

[Close]

BLAST of Voltage-dependent anion channel vs. Ensembl Medaka
Match: vdac1 (voltage dependent anion channel 1 [Source:NCBI gene;Acc:101173964])

HSP 1 Score: 151.369 bits (381), Expect = 6.891e-41
Identity = 83/290 (28.62%), Postives = 164/290 (56.55%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYP--KPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            + +PP+++DLG++A+D+F K Y FGL  +++ +K++        G+ N ++S ++G+ ET +    +G+     W+T N L TE++   +  KGLK     SF P+TGKK    K +YK D++N+  ++ +     D+N   + G +    + +LAG  + F+     +    FA+GY+  +F + T++ D + F   IYQK+N+  +  +++++   +  +++ IAA+Y I   D S+   K+N   ++G  Y   +  G++L+LS+ +D K + +G +  GL + +++
Sbjct:    1 MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSTGSANTETSKVAGSLETKYKWAEHGLTFTEKWNTDNTLGTEITVEDQLAKGLKLTLDSSFSPNTGKKGGKVKTAYKCDHVNVGCDVNY-----DINGTAIHGAAVVGYEGWLAGYQMTFEAGRNKVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNEQLETAVNLSWTAGNSNTRFGIAAKYQI-DPDASF-SAKVNNSSLVGLGYTQTLKPGIKLTLSALLDGKNINAGGHKLGLGLEFQA 283

[Close]

BLAST of Voltage-dependent anion channel vs. Ensembl Medaka
Match: vdac1 (voltage dependent anion channel 1 [Source:NCBI gene;Acc:101173964])

HSP 1 Score: 148.288 bits (373), Expect = 1.506e-39
Identity = 83/284 (29.23%), Postives = 160/284 (56.34%), Query Frame = 3

Query:  105 VMIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTA-SVAIKGNHNIKSSSLSGTFETTHT-TNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYP--KPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGL 944
            + +PP+++DLG++A+D+F K Y FGL  +++ +K++        G+ N ++S ++G+ ET +    +G+     W+T N L TE++   +  KGLK     SF P+TGKK    K +YK D++N+  ++ +     D+N   + G +    + +LAG  + F+     +    FA+GY+  +F + T++ D + F   IYQK+N+  +  +++++   +  +++ IAA+Y I   D S+   K+N   ++G  Y   +  G++L+LS+ +D K + +G +  GL
Sbjct:    1 MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSTGSANTETSKVAGSLETKYKWAEHGLTFTEKWNTDNTLGTEITVEDQLAKGLKLTLDSSFSPNTGKKGGKVKTAYKCDHVNVGCDVNY-----DINGTAIHGAAVVGYEGWLAGYQMTFEAGRNKVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNEQLETAVNLSWTAGNSNTRFGIAAKYQID-PDASF-SAKVNNSSLVGLGYTQTLKPGIKLTLSALLDGKNINAGGHKLGL 277

[Close]

BLAST of Voltage-dependent anion channel vs. Planmine SMEST
Match: SMESG000013661.1 (SMESG000013661.1)

HSP 1 Score: 578.17 bits (1489), Expect = 0.000e+0
Identity = 285/285 (100.00%), Postives = 285/285 (100.00%), Query Frame = 3

Query:  108 MIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTASVAIKGNHNIKSSSLSGTFETTHTTNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            MIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTASVAIKGNHNIKSSSLSGTFETTHTTNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES
Sbjct:    1 MIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTASVAIKGNHNIKSSSLSGTFETTHTTNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 285

[Close]

BLAST of Voltage-dependent anion channel vs. Planmine SMEST
Match: SMESG000000196.1 (SMESG000000196.1)

HSP 1 Score: 353.984 bits (907), Expect = 9.695e-118
Identity = 166/286 (58.04%), Postives = 220/286 (76.92%), Query Frame = 3

Query:  108 MIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTASVAIKGNHNIKSSSLSGTFETTHTT-NYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES 962
            MIPPSFSDLG+AAKDLFDKK+  G+ NVE+ +K D  ++ +K  H+ K+  LSG FE  H+    G+D+   W T NV+  E+SK  + IKGLK VGI++FEP+TG KSLN K+SYKR+YLNINSE +F + KPD+NLN+VLGC++PKPYL G+DL  D   + L+NHTFA+GY+KSDFG   ++K+LS+FN Y+YQKI+   DIG+HV++NK +K +KY IA QY  P SD S++K KINQD ++G VYGC +N+GVQL+LSSEID KKL++GP+NFG+  VYE 
Sbjct:    1 MIPPSFSDLGKAAKDLFDKKFLVGVSNVEIITKKDARTLTVKSKHDHKTKDLSGNFELKHSNIKAGLDMTLKWCTSNVVVAEISKTYERIKGLKNVGILTFEPNTGLKSLNFKDSYKREYLNINSEFLFNSKKPDINLNMVLGCTHPKPYLTGVDLTIDTEGKKLRNHTFALGYQKSDFGALITVKNLSMFNAYVYQKISSFVDIGVHVSHNKANKENKYGIAGQYQFPDSDDSFIKLKINQDTMIGLVYGCTLNNGVQLTLSSEIDGKKLDTGPHNFGVGFVYEQ 286

[Close]

BLAST of Voltage-dependent anion channel vs. Planmine SMEST
Match: SMESG000053095.1 (SMESG000053095.1)

HSP 1 Score: 199.904 bits (507), Expect = 9.445e-59
Identity = 109/285 (38.25%), Postives = 168/285 (58.95%), Query Frame = 3

Query:  108 MIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKN-DTASVAIKGNHNIKSSSLSGTFETTHTTNYGIDIKNTWSTKNVLTTELSKVVKSIK-GLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAIVY 956
            MIPPSF DLG+  KDLF+K + FGL +VE  SK+     + IKG++++K+  L+G+ E  +    G+     W TKN L    S +   IK G K    + F PD+G K +  + S+KR YLN   ++ F NLKP +  +LV+GC+  K YL G ++ +D+N   L  H F+IGY K D  +  S+ + +   T+IYQ+IN N ++G+ + +N NS+ +++ +A +Y   +S  S  KGKI+   I+G  Y     D V ++L++EID K LE G + FG+ + Y
Sbjct:    1 MIPPSFCDLGKTTKDLFNKNFHFGLLSVEYLSKSAQGVELTIKGDNSLKAGKLNGSLEWKYKFENGLKNSVKWDTKNELGVNFS-IENFIKTGSKLSADLGFNPDSGNKKMKMQTSFKRKYLNCGLDMCFTNLKPILIPSLVIGCTESKGYLLGAEITYDLNRMDLTRHKFSIGYHKDDLSLIGSLINKTDIETHIYQRINPNVEVGVQIKWNWNSRNTEFGVAGKYQFDNS--SIFKGKIDNKSILGLGYIFRARDNVDITLNAEIDGKDLEKGGHRFGMGLSY 282

[Close]

BLAST of Voltage-dependent anion channel vs. Planmine SMEST
Match: SMESG000081676.1 (SMESG000081676.1)

HSP 1 Score: 107.071 bits (266), Expect = 1.829e-25
Identity = 68/285 (23.86%), Postives = 143/285 (50.18%), Query Frame = 3

Query:  108 MIPPSFSDLGRAAKDLFDKKYKFGLYNVEV-CSKNDTASVAIKGNHNIKSSSLSGTFET---THTTNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYGCNINDGVQLSLSSEIDAKKLESGPYNFGLAI 950
            M+ P+F+D+G+  KDLFDK +  G + +     K +  S+ I G+ NI S  L  +F+T       N    +   W+T N + + L   V  I+ +K    +++EP +G+KS+  KN+Y  + +N + ++  + ++P + L+ +       P+  G  + FD   Q     ++ + Y      ++  + + +     I++K+  NT++G+  ++  ++K     +A +     +  S +K KI+ +  + F Y     DG++L+  +++D++ +  G + FGL +
Sbjct:    1 MLAPNFNDIGKRIKDLFDKNFPAGFFKISANFPKVNDISLNISGSQNIDSGKLISSFDTKMNMKLANNDFLLTEKWTTANEVQSILEVTV--IENVKSCIELNYEPSSGRKSMKFKNNYSTEMINASGDIECRQIEPILTLSSIFKLVRSIPFYGGGLITFDTYKQRFSKVSYGVQYSNETTNLTGLLTNHNEILFQIFKKLFSNTEVGVESSWKHDTKTPGIGLAMKR--EFTKDSSLKAKIDTNGYLSFGYTFLARDGIKLTFGAKLDSRNINGGGHKFGLQL 281

[Close]

BLAST of Voltage-dependent anion channel vs. Planmine SMEST
Match: SMESG000071615.1 (SMESG000071615.1)

HSP 1 Score: 92.0485 bits (227), Expect = 1.710e-20
Identity = 68/254 (26.77%), Postives = 121/254 (47.64%), Query Frame = 3

Query:  108 MIPPSFSDLGRAAKDLFDKKYKFGLYNVEV-CSKNDTASVAIKGNHNIKSSSLSGTFE-TTHTTNYG-IDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSFEPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYLAGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINKNTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQD--LIMGFVY 854
            M  PSFSDLG+  KDLF+K++  G + +     +    +V   G+ N+ +   S   E     ++YG I +   W+ KN   + +   +K    L     ++ EP  G+ S+  KNSYK D +  + ++ FK LKP+++L+++       P   G  + +D N   +K   + +  +K D  +S S+ +   F   I  KI+   DIG+   +N+  K + +   +Q  +     S VK K+     L +G+ +
Sbjct:    1 MSQPSFSDLGKKFKDLFNKQFPAGFFKLSAKFPETKGLAVNFNGSLNMDTGQFSPNLELKIPISSYGGITLIEKWTAKNEFLSSIE--MKPTSSLTNALEVTLEPTNGQTSIKTKNSYKSDSITTSGDIKFKTLKPEISLSIMTNLIQSIPLHGGGSVTYDFNKNKIKEINYGLQIDKGDICLS-SLGNNKEFMAQICMKISDQVDIGVESGWNQELKTTTFGTVSQLRLDSG--SLVKAKVESTGFLSLGYCF 249

The following BLAST results are available for this feature:

BLAST of Voltage-dependent anion channel vs. Ensembl Human
BLAST of Voltage-dependent anion channel vs. Ensembl Celegans
BLAST of Voltage-dependent anion channel vs. Ensembl Fly
BLAST of Voltage-dependent anion channel vs. Ensembl Zebrafish
BLAST of Voltage-dependent anion channel vs. Ensembl Xenopus
BLAST of Voltage-dependent anion channel vs. Ensembl Mouse
BLAST of Voltage-dependent anion channel vs. UniProt/SwissProt
BLAST of Voltage-dependent anion channel vs. TrEMBL
BLAST of Voltage-dependent anion channel vs. Ensembl Cavefish
BLAST of Voltage-dependent anion channel vs. Ensembl Sea Lamprey
BLAST of Voltage-dependent anion channel vs. Ensembl Yeast
BLAST of Voltage-dependent anion channel vs. Ensembl Nematostella
BLAST of Voltage-dependent anion channel vs. Ensembl Medaka
BLAST of Voltage-dependent anion channel vs. Planmine SMEST

BLAST of Voltage-dependent anion channel vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
VDAC2	3.087e-46	31.38	voltage dependent anion channel 2 [Source:HGNC Sym...	[more]
VDAC2	3.087e-46	31.38	voltage dependent anion channel 2 [Source:HGNC Sym...	[more]
VDAC2	5.509e-46	31.60	voltage dependent anion channel 2 [Source:HGNC Sym...	[more]
VDAC1	1.967e-45	29.86	voltage dependent anion channel 1 [Source:HGNC Sym...	[more]
VDAC1	1.967e-45	29.86	voltage dependent anion channel 1 [Source:HGNC Sym...	[more]

BLAST of Voltage-dependent anion channel vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
vdac-1	6.845e-22	24.31	Probable voltage-dependent anion-selective channel...	[more]

BLAST of Voltage-dependent anion channel vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
porin	7.125e-40	29.97	gene:FBgn0004363 transcript:FBtr0100584	[more]
porin	7.125e-40	29.97	gene:FBgn0004363 transcript:FBtr0080183	[more]
porin	7.125e-40	29.97	gene:FBgn0004363 transcript:FBtr0305260	[more]
porin	7.125e-40	29.97	gene:FBgn0004363 transcript:FBtr0332029	[more]
porin	7.125e-40	29.97	gene:FBgn0004363 transcript:FBtr0080182	[more]

BLAST of Voltage-dependent anion channel vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
vdac3	9.969e-47	33.33	voltage-dependent anion channel 3 [Source:ZFIN;Acc...	[more]
vdac2	1.166e-45	30.56	voltage-dependent anion channel 2 [Source:ZFIN;Acc...	[more]
vdac2	1.166e-45	30.56	voltage-dependent anion channel 2 [Source:ZFIN;Acc...	[more]
vdac1	1.055e-43	30.56	voltage-dependent anion channel 1 [Source:ZFIN;Acc...	[more]
zgc:56235	5.649e-41	30.90	zgc:56235 [Source:ZFIN;Acc:ZDB-GENE-040426-954]	[more]

BLAST of Voltage-dependent anion channel vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
vdac2	9.637e-47	31.94	voltage-dependent anion channel 2 [Source:NCBI gen...	[more]
vdac2	1.019e-46	31.94	voltage-dependent anion channel 2 [Source:NCBI gen...	[more]
vdac2	1.102e-46	31.94	voltage-dependent anion channel 2 [Source:NCBI gen...	[more]
vdac2	1.835e-46	31.94	voltage-dependent anion channel 2 [Source:NCBI gen...	[more]
vdac2	2.135e-46	31.94	voltage-dependent anion channel 2 [Source:NCBI gen...	[more]

BLAST of Voltage-dependent anion channel vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Vdac1	7.277e-46	29.66	voltage-dependent anion channel 1 [Source:MGI Symb...	[more]
Vdac1	2.707e-45	29.51	voltage-dependent anion channel 1 [Source:MGI Symb...	[more]
Vdac2	8.878e-45	30.90	voltage-dependent anion channel 2 [Source:MGI Symb...	[more]
Vdac2	8.878e-45	30.90	voltage-dependent anion channel 2 [Source:MGI Symb...	[more]
Vdac2	1.162e-44	30.69	voltage-dependent anion channel 2 [Source:MGI Symb...	[more]

BLAST of Voltage-dependent anion channel vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P68002\|VDAC2_BOVIN	9.225e-46	31.38	Voltage-dependent anion-selective channel protein ...	[more]
sp\|P68003\|VDAC2_RABIT	1.010e-45	31.38	Voltage-dependent anion-selective channel protein ...	[more]
sp\|Q9MZ15\|VDAC2_PIG	1.354e-45	31.38	Voltage-dependent anion-selective channel protein ...	[more]
sp\|P45880\|VDAC2_HUMAN	1.483e-45	31.38	Voltage-dependent anion-selective channel protein ...	[more]
sp\|P82013\|VDAC2_MELGA	3.353e-45	32.17	Voltage-dependent anion-selective channel protein ...	[more]

BLAST of Voltage-dependent anion channel vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1S3IT01	1.483e-49	36.14	voltage-dependent anion-selective channel protein ...	[more]
R7VH43	3.867e-49	34.60	Uncharacterized protein OS=Capitella teleta OX=283...	[more]
A0A401NLF2	5.567e-47	32.76	Uncharacterized protein OS=Scyliorhinus torazame O...	[more]
A0A2G8LNP3	1.295e-46	35.56	Putative voltage-dependent anion-selective channel...	[more]
A0A401T5U1	4.117e-46	32.53	Uncharacterized protein OS=Chiloscyllium punctatum...	[more]

BLAST of Voltage-dependent anion channel vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
VDAC2	1.846e-47	32.75	voltage-dependent anion-selective channel protein ...	[more]
vdac3	1.163e-46	33.10	voltage dependent anion channel 3 [Source:NCBI gen...	[more]
vdac2	1.287e-46	31.25	voltage-dependent anion-selective channel protein ...	[more]
vdac1	3.065e-41	30.34	voltage dependent anion channel 1 [Source:NCBI gen...	[more]
vdac3	7.876e-39	32.81	voltage dependent anion channel 3 [Source:NCBI gen...	[more]

BLAST of Voltage-dependent anion channel vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
vdac2	2.302e-48	32.64	voltage-dependent anion channel 2 [Source:ZFIN;Acc...	[more]
ENSPMAT00000005399.1	2.415e-34	27.37	pep scaffold:Pmarinus_7.0:GL479471:12985:19564:-1 ...	[more]

BLAST of Voltage-dependent anion channel vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
POR1	4.540e-12	21.92	Mitochondrial porin (voltage-dependent anion chann...	[more]

BLAST of Voltage-dependent anion channel vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO31835	1.037e-37	29.12	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Voltage-dependent anion channel vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
vdac2	1.592e-47	31.94	voltage-dependent anion-selective channel protein ...	[more]
vdac3	2.259e-46	32.99	voltage-dependent anion-selective channel protein ...	[more]
VDAC2	1.263e-42	30.90	voltage-dependent anion-selective channel protein ...	[more]
vdac1	6.891e-41	28.62	voltage dependent anion channel 1 [Source:NCBI gen...	[more]
vdac1	1.506e-39	29.23	voltage dependent anion channel 1 [Source:NCBI gen...	[more]

BLAST of Voltage-dependent anion channel vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000013661.1	0.000e+0	100.00	SMESG000013661.1	[more]
SMESG000000196.1	9.695e-118	58.04	SMESG000000196.1	[more]
SMESG000053095.1	9.445e-59	38.25	SMESG000053095.1	[more]
SMESG000081676.1	1.829e-25	23.86	SMESG000081676.1	[more]
SMESG000071615.1	1.710e-20	26.77	SMESG000071615.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30010334 ID=SMED30010334|Name=Voltage-dependent anion channel|organism=Schmidtea mediterranea sexual|type=transcript|length=2015bp
ATTAAACCTTGTTTAATTTCGACGGCATATAGAAACAAGTTCAAATTTAC
TTGTAATCAAACAAAGGATTGTTTTAATTAATATAAATTCATAAAACTCA
GCACGTTATGATTCCACCTTCATTTTCAGATCTTGGTAGAGCCGCAAAAG
ATTTATTTGATAAAAAATACAAATTTGGATTATATAATGTTGAGGTGTGT
TCAAAAAATGACACGGCTAGTGTGGCCATTAAGGGGAATCATAACATTAA
ATCGAGTTCTTTATCGGGAACTTTTGAAACAACTCATACAACAAATTATG
GAATCGATATCAAAAATACGTGGTCGACGAAAAATGTATTAACAACTGAA
TTATCAAAAGTTGTCAAATCTATAAAAGGATTAAAATGTGTAGGTATAAT
GTCATTCGAGCCTGACACAGGGAAAAAATCGTTAAATGCCAAGAATTCGT
ATAAAAGGGATTACTTAAACATTAATTCTGAATTGGTATTCAAAAATTTG
AAGCCAGATGTTAATTTGAATTTAGTTCTAGGATGCAGTTATCCAAAGCC
ATATCTTGCTGGTCTTGATTTGAATTTTGATATAAATAATCAACATTTGA
AAAATCATACTTTTGCAATCGGCTATGAAAAATCAGATTTCGGTATTTCT
ACATCAATGAAAGATCTCTCACTTTTTAATACATACATTTATCAAAAAAT
TAACAAAAATACCGATATTGGAATTCATGTGACTTATAATAAAAATTCGA
AAATCTCTAAATACGAAATAGCCGCCCAATATATGATTCCGCATTCAGAC
CGTTCCTATGTTAAAGGAAAAATTAATCAGGACCTTATCATGGGTTTCGT
TTACGGGTGCAATATTAACGATGGCGTCCAATTATCTTTATCCAGTGAAA
TTGATGCCAAGAAGTTAGAGAGCGGTCCTTACAATTTTGGATTAGCTATC
GTTTATGAATCATAAATAGTCCTGTTTTAGTCAATTTAAACTATTATTTC
AATATATTTTGTTTAAAACTTAAATGATTGCAATGCTTTAATTTCTTTTT
ATCATTATAACGAGTTTTAATCAATTAAATTATATGAGGATGATTTATAA
TATAACTTCGTATTAGAATAATTTTAATTAAGTCATTTATAATTTATTAA
ATGCATTGTCCTCTTATGAAAATTGCGCCTCCTGTAGATTCTGCGATTTT
GTCGCTAACATGTATATATTTATTTTTGCTAGTGGTTCTTAACCTTTTTA
TTGGTCACCATGCCCTTAAATCTGAAAATAAGCTCATACTTATGGAGAAA
ATGCGTTTACTATATCTATTAATATATAACACAATATCTAAATTTAATGG
TTACTTTGTTTATTCATAATACTTGCTTACGAGGCTTACGAATTTATAGA
ACAAATAGCTTTGATTGTCAAAGATTTTTAGGCGGTATGTGAACATACTC
ATGATTTATGCATTTCTCCTGTATTATTTTAAATATTTTCTATAAAATTA
TAAAGAAAATGTATAATGAAAAATACTTTATAACAATTAGTGGTTTGAGA
AACTGCTTCAATGCTGTTTAAAAATGATCCGATAGTTGCATGGGAAACTG
AAAAATTTTACTTACAGGACTTTCAATATAAGTTGTAAACAATTAGCCTA
AAATTTCAATATATCCGAAATTAGGAAATGTCTCAGTAAGAAGGTAAAAC
ACAGTATTTACATTTAAATCTTTCTAAAATACTTAGACTAATGTTATTAA
CTTTTGTAATTATCATTCAGTACAAATAAAAGTGGCACTCTAACTTCAGC
GTTTGTAATCGCTATTATTGCAGCCTTTTCAAAATCAACTAGCACTTTCA
AACGTACTAGCTTCGGAAGCTTCAATTTCAGAATTTCCAACAAAGGCGTT
AATTTTTTATTCTATAGTAAAAAATTAACACAAGACATACAGAATTTTTA
ATTTATCACATAAAAACTATAATTTTTATTAACTCAAATAATTTATGGAT
TTCTATATATTTTTT

protein sequence of SMED30010334-orf-1

>SMED30010334-orf-1 ID=SMED30010334-orf-1|Name=SMED30010334-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=286bp
MIPPSFSDLGRAAKDLFDKKYKFGLYNVEVCSKNDTASVAIKGNHNIKSS
SLSGTFETTHTTNYGIDIKNTWSTKNVLTTELSKVVKSIKGLKCVGIMSF
EPDTGKKSLNAKNSYKRDYLNINSELVFKNLKPDVNLNLVLGCSYPKPYL
AGLDLNFDINNQHLKNHTFAIGYEKSDFGISTSMKDLSLFNTYIYQKINK
NTDIGIHVTYNKNSKISKYEIAAQYMIPHSDRSYVKGKINQDLIMGFVYG
CNINDGVQLSLSSEIDAKKLESGPYNFGLAIVYES*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0015698	inorganic anion transport
GO:0044070	regulation of anion transport
GO:0006820	anion transport
GO:0055085	transmembrane transport
GO:0001662	behavioral fear response
GO:0006810	transport
GO:0006811	ion transport
GO:0006851	mitochondrial calcium ion transmembrane transport
GO:0006915	apoptotic process
GO:0007268	chemical synaptic transmission
GO:0007270	neuron-neuron synaptic transmission
GO:0007612	learning
GO:0030855	epithelial cell differentiation
GO:0098656	anion transmembrane transport
GO:1903146	regulation of mitophagy
GO:1903959	regulation of anion transmembrane transport
GO:2000378	negative regulation of reactive oxygen species metabolic process

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000070	intestinal phagocyte
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR030277	VDAC2
IPR001925	Porin_Euk
IPR027246	Porin_Euk/Tom40
IPR023614	Porin_dom_sf

Vocabulary: **cellular component**
Term	Definition
GO:0005741	mitochondrial outer membrane
GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005886	plasma membrane
GO:0008021	synaptic vesicle
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0042645	mitochondrial nucleoid
GO:0043209	myelin sheath
GO:0043234	protein complex
GO:0045121	membrane raft
GO:0046930	pore complex
GO:0070062	extracellular exosome

Vocabulary: **molecular function**
Term	Definition
GO:0008308	voltage-gated anion channel activity
GO:0000166	nucleotide binding
GO:0005253	anion channel activity
GO:0005515	protein binding
GO:0015288	porin activity
GO:0019901	protein kinase binding
GO:0032403	protein complex binding
GO:0044325	ion channel binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001925	Porin, eukaryotic type	PRINTS	PR00185	EUKARYTPORIN	coord: 147..158 score: 38.46 coord: 249..266 score: 35.47 coord: 4..19 score: 55.77 coord: 65..80 score: 38.46
IPR001925	Porin, eukaryotic type	PANTHER	PTHR11743	VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL	coord: 2..284
IPR027246	Eukaryotic porin/Tom40	PFAM	PF01459	Porin_3	coord: 3..278 e-value: 2.3E-44 score: 151.9
IPR023614	Porin domain superfamily	GENE3D	G3DSA:2.40.160.10		coord: 1..285 e-value: 2.2E-71 score: 242.4
IPR030277	Voltage-dependent anion-selective channel protein 2	PANTHER	PTHR11743:SF12	VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL PROTEIN 2	coord: 2..284
None	No IPR available	CDD	cd07306	Porin3_VDAC	coord: 3..284 e-value: 5.35754E-60 score: 190.112