Tetraspanin

Overview
NameTetraspanin
Smed IDSMED30010326
Length (bp)1154
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Tetraspanin (SMED30010326) t-SNE clustered cells

Violin plots show distribution of expression levels for Tetraspanin (SMED30010326) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Tetraspanin (SMED30010326) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Tetraspanin (SMED30010326) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30010326

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30010326SMESG000078589.1 SmedASXL_008055SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30010326SMESG000078589.1 dd_Smed_v4_2698_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30010326SMESG000078589.1 dd_Smed_v4_2698_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30010326SMESG000078589.1 dd_Smed_v4_2698_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30010326SMESG000078589.1 dd_Smed_v4_2698_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30010326SMESG000078589.1 dd_Smed_v4_2698_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30010326SMESG000078589.1 dd_Smed_v4_2698_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30010326SMESG000078589.1 dd_Smed_v4_2698_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30010326SMESG000078589.1 dd_Smed_v6_2698_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
zeta neoblastSMED30010326SMESG000078589.1 dd_Smed_v4_2698_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Tetraspanin vs. Ensembl Human
Match: TSPAN3 (tetraspanin 3 [Source:HGNC Symbol;Acc:HGNC:17752])

HSP 1 Score: 57.7658 bits (138), Expect = 5.975e-9
Identity = 58/233 (24.89%), Postives = 102/233 (43.78%), Query Frame = 2 
Query:  443 VSFENTDNTVLDVI----AIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFACIVARRKD*D 1129
            +++++ D+   DV     A+V+I  GA  F+ G  GCC  I+E+R  L T+ I++    + E+ + +   V   K  N++  S++  + K +NG    N    ++    +   L CCGI + SD+   N +W     K QS P+ CC+                        +NC        +L  +GC   ++K L+  +  VI   +     ++  +  ACIV  R+  D
Sbjct:   36 ITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQK-VYKTYNG---TNPDAASRAIDYVQRQLHCCGIHNYSDWE--NTDW-FKETKNQSVPLSCCRET---------------------ASNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD 240
[Close]
BLAST of Tetraspanin vs. Ensembl Human
Match: TSPAN1 (tetraspanin 1 [Source:HGNC Symbol;Acc:HGNC:20657])

HSP 1 Score: 55.8398 bits (133), Expect = 2.901e-8
Identity = 68/247 (27.53%), Postives = 111/247 (44.94%), Query Frame = 2 
Query:  293 CKSFSKXXXXXXXXXXXXXGAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRN 1033
            C SF K ++I+FN+L F+ GAA+L VGIWV +D ++  +I     +  S + F N        +   LI  G   F  GF GC GA  E++  L+T+  ++    IAE+   + A V      + L+  +   IKKD+      +   FT+++   M  L+CCG  + +DF  +         +  + P  CC  N+N+   A      +   D+ V                +GC N L+  ++ N
Sbjct:    3 CFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFG--PLSSSAMQFVN--------VGYFLIAAGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAIKKDY-----GSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPY-----FKENSAFPPFCC--NDNVTNTANETCTKQKAHDQKV----------------EGCFNQLLYDIRTN 211
[Close]
BLAST of Tetraspanin vs. Ensembl Human
Match: CD82 (CD82 molecule [Source:HGNC Symbol;Acc:HGNC:6210])

HSP 1 Score: 51.2174 bits (121), Expect = 1.082e-7
Identity = 30/78 (38.46%), Postives = 40/78 (51.28%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITY 583
            GA ILG G+W+  DKS+   +L+             T ++ L + A V I  GA T + GF GC GA+ E R LL  Y
Sbjct:   24 GAVILGFGVWILADKSSFISVLQ-------------TSSSSLRMGAYVFIGVGAVTMLMGFLGCIGAVNEVRCLLGLY 88
[Close]
BLAST of Tetraspanin vs. Ensembl Human
Match: CD82 (CD82 molecule [Source:HGNC Symbol;Acc:HGNC:6210])

HSP 1 Score: 51.2174 bits (121), Expect = 1.282e-7
Identity = 30/78 (38.46%), Postives = 40/78 (51.28%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITY 583
            GA ILG G+W+  DKS+   +L+             T ++ L + A V I  GA T + GF GC GA+ E R LL  Y
Sbjct:   24 GAVILGFGVWILADKSSFISVLQ-------------TSSSSLRMGAYVFIGVGAVTMLMGFLGCIGAVNEVRCLLGLY 88
[Close]
BLAST of Tetraspanin vs. Ensembl Human
Match: CD82 (CD82 molecule [Source:HGNC Symbol;Acc:HGNC:6210])

HSP 1 Score: 51.6026 bits (122), Expect = 2.557e-7
Identity = 45/156 (28.85%), Postives = 72/156 (46.15%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTN 817
            GA ILG G+W+  DKS+   +L+             T ++ L + A V I  GA T + GF GC GA+ E R LL  Y   +   +IA++  G        K   ++   +  LI +D+N   ++        +  +   ++CCG V  S +N T+
Sbjct:    5 GAVILGFGVWILADKSSFISVLQ-------------TSSSSLRMGAYVFIGVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTELI-RDYN---SSREDSLQDAWDYVQAQVKCCGWV--SFYNWTD 141
[Close]
BLAST of Tetraspanin vs. Ensembl Celegans
Match: tsp-11 (Tetraspanin [Source:UniProtKB/TrEMBL;Acc:Q17526])

HSP 1 Score: 58.5362 bits (140), Expect = 1.998e-9
Identity = 60/200 (30.00%), Postives = 85/200 (42.50%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDK---SNLFEILRKIKIEGSDVSFEN--TDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGA----FANNATQFTKIFTA---IMFDLQCCGIVDESDFNVTNLNW-AISSGKLQSHPVGCCKLNNNLKYNAQSN 910
            G   LG+G+W+ +DK    NL     K++    D    +  T  T +     +L V G    V  F GCCGA KE R LL  YS  +   +  +I   IYA +    F N   D L + +K  +NG      +NN      + TA   IM +  CCG VD       N  W  ++ G+ Q  P  CC  + + +     N
Sbjct:   33 GLICLGIGLWLVLDKYAIDNLAFATAKVQGYDQDAGLRDLATKPTAVRQFGYLLFVGGFIVIVVAFLGCCGAAKEWRPLLCCYSSCLMLILAIQIAATIYAFLHSHMFENDFRDILHSSLKM-YNGTDNMKVSNNPQDGLLVKTAWDKIMIEKSCCG-VDSKIGEFNNSGWYQLNHGRYQ-FPPACCPPDEHGRLRPYCN 229
[Close]
BLAST of Tetraspanin vs. Ensembl Celegans
Match: tsp-11 (Tetraspanin [Source:UniProtKB/TrEMBL;Acc:Q17526])

HSP 1 Score: 58.5362 bits (140), Expect = 1.998e-9
Identity = 60/200 (30.00%), Postives = 85/200 (42.50%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDK---SNLFEILRKIKIEGSDVSFEN--TDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGA----FANNATQFTKIFTA---IMFDLQCCGIVDESDFNVTNLNW-AISSGKLQSHPVGCCKLNNNLKYNAQSN 910
            G   LG+G+W+ +DK    NL     K++    D    +  T  T +     +L V G    V  F GCCGA KE R LL  YS  +   +  +I   IYA +    F N   D L + +K  +NG      +NN      + TA   IM +  CCG VD       N  W  ++ G+ Q  P  CC  + + +     N
Sbjct:   33 GLICLGIGLWLVLDKYAIDNLAFATAKVQGYDQDAGLRDLATKPTAVRQFGYLLFVGGFIVIVVAFLGCCGAAKEWRPLLCCYSSCLMLILAIQIAATIYAFLHSHMFENDFRDILHSSLKM-YNGTDNMKVSNNPQDGLLVKTAWDKIMIEKSCCG-VDSKIGEFNNSGWYQLNHGRYQ-FPPACCPPDEHGRLRPYCN 229
[Close]
BLAST of Tetraspanin vs. Ensembl Fly
Match: Tsp66E (gene:FBgn0035936 transcript:FBtr0076507)

HSP 1 Score: 65.0846 bits (157), Expect = 1.265e-11
Identity = 54/182 (29.67%), Postives = 88/182 (48.35%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNG-AFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLK 892
            G  I GVG+W+ VDK +L  +L+ ++ E  +   + T    ++ +A VL+V GA  F   F G  GA++E+R LL TY   +   +IAEI  G         F +++    KN ++      +   N    + ++  +M +  CCGI D  DF+ +   W    G  ++ P  CC L +  K
Sbjct:   25 GTIIFGVGLWLAVDKHSLIALLKLVESERIE---QFTQPQAIEQLAYVLLVIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAF----FKDKVRAESKNFLQTTITSYSLGENVDATSLMWNQLMGNFGCCGINDYHDFDASP-AWVNGKGN-RTIPDACCILKDVAK 197
[Close]
BLAST of Tetraspanin vs. Ensembl Fly
Match: Tsp66E (gene:FBgn0035936 transcript:FBtr0076506)

HSP 1 Score: 65.0846 bits (157), Expect = 1.265e-11
Identity = 54/182 (29.67%), Postives = 88/182 (48.35%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNG-AFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLK 892
            G  I GVG+W+ VDK +L  +L+ ++ E  +   + T    ++ +A VL+V GA  F   F G  GA++E+R LL TY   +   +IAEI  G         F +++    KN ++      +   N    + ++  +M +  CCGI D  DF+ +   W    G  ++ P  CC L +  K
Sbjct:   25 GTIIFGVGLWLAVDKHSLIALLKLVESERIE---QFTQPQAIEQLAYVLLVIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAF----FKDKVRAESKNFLQTTITSYSLGENVDATSLMWNQLMGNFGCCGINDYHDFDASP-AWVNGKGN-RTIPDACCILKDVAK 197
[Close]
BLAST of Tetraspanin vs. Ensembl Fly
Match: Tsp66E (gene:FBgn0035936 transcript:FBtr0076508)

HSP 1 Score: 65.0846 bits (157), Expect = 1.265e-11
Identity = 54/182 (29.67%), Postives = 88/182 (48.35%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNG-AFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLK 892
            G  I GVG+W+ VDK +L  +L+ ++ E  +   + T    ++ +A VL+V GA  F   F G  GA++E+R LL TY   +   +IAEI  G         F +++    KN ++      +   N    + ++  +M +  CCGI D  DF+ +   W    G  ++ P  CC L +  K
Sbjct:   25 GTIIFGVGLWLAVDKHSLIALLKLVESERIE---QFTQPQAIEQLAYVLLVIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAF----FKDKVRAESKNFLQTTITSYSLGENVDATSLMWNQLMGNFGCCGINDYHDFDASP-AWVNGKGN-RTIPDACCILKDVAK 197
[Close]
BLAST of Tetraspanin vs. Ensembl Fly
Match: Tsp26A (gene:FBgn0031760 transcript:FBtr0307300)

HSP 1 Score: 49.6766 bits (117), Expect = 1.629e-6
Identity = 73/261 (27.97%), Postives = 114/261 (43.68%), Query Frame = 2 
Query:  359 ILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKK--FVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFD-LQCCGIVDESDFNVTNL----NWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETT---VNVELNK----DGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFA 1099
            +L VGIW   +K  +F  + ++     D +F             VLI+ G  TF+ GF G  GA++EN  LL  Y+I ++  +IAEIG    A V + K    +Q ++ LK  I+      +  +A Q   +   I  D LQCCGI    D++  N     + AI S +    P  CC+                  Q+ +    C ++       +EL+K     GC+ A  + ++ NL I+    I +  F+I  I FA
Sbjct:   37 VLSVGIWAWSEK-GMFRNIARLHFIALDPAF-------------VLIILGGVTFLLGFMGSVGALRENTCLLGAYAIFLSVLLIAEIGFCAVAFVLKDKGWIKDQATEGLKAFIRH-----YREDADQ-QNLIDWIQEDWLQCCGIDGPKDWDSNNYFNCSSIAIGSREACGVPFSCCRRRP---------------QEVIKNKQCGYDVRKEGYGMELSKIIYEKGCVQAGEEWMEHNLIIISATVIVVMFFQILGICFA 262
[Close]
BLAST of Tetraspanin vs. Ensembl Zebrafish
Match: tspan34 (tetraspanin 34 [Source:ZFIN;Acc:ZDB-GENE-060825-202])

HSP 1 Score: 67.781 bits (164), Expect = 1.243e-12
Identity = 53/178 (29.78%), Postives = 86/178 (48.31%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXX---XXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCK 874
            GAA+L VGIWV VD+ +L   L  I  E +        N     I  +LI  GAF  + GF GCCGA+KE++ +L+T+ I+V    + E+   +         ++ +N++   +   IK ++          F+ I+   M +L+CCG  + +DF+ +N     S      +P  CC 
Sbjct:   13 GAAVLAVGIWVAVDRVSLLGFLEHI--EDAPPELAQLAN-----IGYLLIGVGAFLAIMGFLGCCGAVKESKCMLLTFFIIVLIIFLVEVAAAVVLFVFEPVVQETLNEIGQKVAKSIKDNY-----GKDEPFSSIWNTTMNELKCCGYNNYTDFSGSNFVEETS-----MYPEKCCS 173
[Close]
BLAST of Tetraspanin vs. Ensembl Zebrafish
Match: tspan35 (tetraspanin 35 [Source:ZFIN;Acc:ZDB-GENE-040426-1362])

HSP 1 Score: 60.8474 bits (146), Expect = 3.336e-10
Identity = 67/232 (28.88%), Postives = 107/232 (46.12%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENR---ILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLS-DSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRN 1033
            G  ILGVGIWVKVD  ++   ++ +    S +        VL+V   +LI  GA   V GF GCCGA+KE+R   +L     +++  A +A   + +      +  + QL  D++K+L + DF           T ++   M  ++CCG  + +DF  TN ++ ++S K  ++PV CC                        T+ C     +N  +   GC  ALIKL+ +N
Sbjct:   22 GGVILGVGIWVKVDNGSILNFMQSLPGASSQM------GQVLNV-GYLLIALGAVLVVLGFLGCCGAVKESRCMLMLFFIIILIIFIAEVAGAIVILAFRPLAETLIKQLGVDAVKSL-QSDF-----GKNQDVTGLWNTTMTGMKCCGFNNYTDF--TN-SFFVNSTK--NYPVQCCN-----------------------TSPCNQAAVMNSTVT--GCFPALIKLVDKN 210
[Close]
BLAST of Tetraspanin vs. Ensembl Zebrafish
Match: tspan18a (tetraspanin 18a [Source:ZFIN;Acc:ZDB-GENE-040718-232])

HSP 1 Score: 58.151 bits (139), Expect = 2.959e-9
Identity = 51/175 (29.14%), Postives = 84/175 (48.00%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCK 874
            G+ +LGVGIWV VD +   EI+                N++L      +++ G   F+ GF GCCGAI+EN+ LL+ + +L+    +AE+ + I A +  +       D     +K  + G   N+   FT  + AIM    CCG+    DF+  +L   ++  ++   P  CC+
Sbjct:   36 GSFLLGVGIWVLVDPTGFREIV--------------AANSLLFTGVYAILIMGGMLFLLGFLGCCGAIRENKCLLLFFFMLILVIFLAELAVAILAFIFREHLTR---DYFTKELKTHYQG--TNSTDVFTSTWNAIMTTFNCCGVNSAEDFDDQSLFRRLNPSRIV--PEVCCQ 189
[Close]
BLAST of Tetraspanin vs. Ensembl Zebrafish
Match: cd151l (CD151 antigen, like [Source:ZFIN;Acc:ZDB-GENE-040426-1868])

HSP 1 Score: 57.3806 bits (137), Expect = 3.436e-9
Identity = 49/178 (27.53%), Postives = 82/178 (46.07%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISS---GKLQSHPVGCCK 874
            G A++ VGIW  ++KS+   +L                + +  V A +LI+ G    +TG  GCC   KE R LL  Y +L+    + EI  G+ A +  ++  ++L ++L+  + + +N    +     TK    +  + +CCG    SD+   +  W  SS   G+L   P  CCK
Sbjct:   31 GVAVMAVGIWTVIEKSDYISLL---------------SSKIYAVSAYILIMAGVIVMITGVLGCCATFKEQRRLLRVYFVLLLCIFLLEILAGVLAYIYYQQLNDELKENLRETMVQKYN---QSEQEHVTKAVDKLQQEFKCCGSNSSSDW--VDSAWIRSSEADGRLV--PDSCCK 186
[Close]
BLAST of Tetraspanin vs. Ensembl Zebrafish
Match: tspan18a (tetraspanin 18a [Source:ZFIN;Acc:ZDB-GENE-040718-232])

HSP 1 Score: 57.7658 bits (138), Expect = 3.526e-9
Identity = 51/175 (29.14%), Postives = 84/175 (48.00%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCK 874
            G+ +LGVGIWV VD +   EI+                N++L      +++ G   F+ GF GCCGAI+EN+ LL+ + +L+    +AE+ + I A +  +       D     +K  + G   N+   FT  + AIM    CCG+    DF+  +L   ++  ++   P  CC+
Sbjct:   24 GSFLLGVGIWVLVDPTGFREIV--------------AANSLLFTGVYAILIMGGMLFLLGFLGCCGAIRENKCLLLFFFMLILVIFLAELAVAILAFIFREHLTR---DYFTKELKTHYQG--TNSTDVFTSTWNAIMTTFNCCGVNSAEDFDDQSLFRRLNPSRIV--PEVCCQ 177
[Close]
BLAST of Tetraspanin vs. Ensembl Xenopus
Match: cd82 (CD82 molecule [Source:NCBI gene;Acc:394799])

HSP 1 Score: 60.4622 bits (145), Expect = 7.714e-10
Identity = 57/189 (30.16%), Postives = 89/189 (47.09%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLI-KKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDF-------NVTNLNWAISSGKLQSHPVGCCKLNNNLK 892
            GA ILG GIW+ VDK++   +L+             T ++ L   + +LI  G FT V GF GC GA+ E R LL  Y   +   +IA++  GI   ++      ++S  +  LI   D+     N + + T  +  I  +L+CCG  +  ++       N TN  +  S  K QS P G C+ N  ++
Sbjct:   25 GAVILGFGIWILVDKTSFIAVLQ-------------TSSSYLRTGSYILIAVGGFTMVMGFLGCLGAVNEIRCLLGLYFSFLLIILIAQVAAGILIYLQRDTLKTEMSSIIHELIVTYDYEDG-KNTSAETT--WDYIQTNLRCCGWTNYQNWTANTVVQNSTN-QYPCSCMKNQSSPNGFCQYNGTVE 196
[Close]
BLAST of Tetraspanin vs. Ensembl Xenopus
Match: wdr74 (WD repeat domain 74 [Source:Xenbase;Acc:XB-GENE-969801])

HSP 1 Score: 60.077 bits (144), Expect = 8.519e-10
Identity = 56/213 (26.29%), Postives = 95/213 (44.60%), Query Frame = 2 
Query:  293 CKSFSKXXXXXXXXXXXXXGAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVI--AIVLIVFGAFTFVTGFCGCCGAIKENR---ILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLK 916
            C SF K ++ +FN + F+ G A+LG+G+WVKVD  +  +IL             +    ++ V+    + I  G F  + GF GCCGA+KE+R   +L     +++  A +A   + +      + F+  L +     +   +       + + T I+ A M +L+CCG     DF     N        Q  PV C  ++   KY    ++K
Sbjct:    3 CFSFLKTMMFVFNGIIFLGGVAVLGIGVWVKVDGGSFLQILG------------SAAPQLMQVVNVGYLCIAVGGFLILMGFLGCCGAVKESRCMLMLFFIIILIIFIAEVAGAVVVLAFSSVSRIFIEYLGNVAVKYLHYQY-----GESDELTTIWNATMKELKCCGFYSYEDFT----NSTYYQRNQQYPPVCCANISPCQKYKIDPDVK 194
[Close]
BLAST of Tetraspanin vs. Ensembl Xenopus
Match: cd82 (CD82 molecule [Source:NCBI gene;Acc:394799])

HSP 1 Score: 60.077 bits (144), Expect = 1.187e-9
Identity = 57/189 (30.16%), Postives = 89/189 (47.09%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLI-KKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDF-------NVTNLNWAISSGKLQSHPVGCCKLNNNLK 892
            GA ILG GIW+ VDK++   +L+             T ++ L   + +LI  G FT V GF GC GA+ E R LL  Y   +   +IA++  GI   ++      ++S  +  LI   D+     N + + T  +  I  +L+CCG  +  ++       N TN  +  S  K QS P G C+ N  ++
Sbjct:   38 GAVILGFGIWILVDKTSFIAVLQ-------------TSSSYLRTGSYILIAVGGFTMVMGFLGCLGAVNEIRCLLGLYFSFLLIILIAQVAAGILIYLQRDTLKTEMSSIIHELIVTYDYEDG-KNTSAETT--WDYIQTNLRCCGWTNYQNWTANTVVQNSTN-QYPCSCMKNQSSPNGFCQYNGTVE 209
[Close]
BLAST of Tetraspanin vs. Ensembl Xenopus
Match: gpr88 (G protein-coupled receptor 88 [Source:Xenbase;Acc:XB-GENE-984668])

HSP 1 Score: 56.6102 bits (135), Expect = 1.366e-8
Identity = 46/168 (27.38%), Postives = 78/168 (46.43%), Query Frame = 2 
Query:  374 IWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQ-FTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCK 874
            +WV VD +   EI+                  +L + A +++  G   F+ GF GCCGAI+EN+ LL+ + + +    +AE+   I A +  +   N   D     +KK ++G   +N+T+ F+  + +IM    CCG+    DFN  +   A+        P  CC+
Sbjct:   32 VWVFVDPTGFREII--------------ATTPLLFMGAYLVLAMGGMLFLLGFLGCCGAIRENKCLLVFFFMFILVIFLAELSAAILAFLFRE---NLSKDFFAREVKKHYHG---DNSTEVFSSTWNSIMITFGCCGVNGPEDFNDAHRFRAMH--PFAPVPEACCR 177
[Close]
BLAST of Tetraspanin vs. Ensembl Xenopus
Match: tspan1 (tetraspanin 1 [Source:NCBI gene;Acc:548861])

HSP 1 Score: 53.1434 bits (126), Expect = 1.943e-7
Identity = 55/220 (25.00%), Postives = 97/220 (44.09%), Query Frame = 2 
Query:  374 IWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRN 1033
            IWV VD ++  +I   +    + + F N        +   LI  G+   + GF GCCGA +E++ LL+T+  ++    IAE+   + A V        L   LK +++ ++      +    TKI+ + M +L CCG  + +DF+    N    +   Q +P  CC        N+ S+            + C  +  +N  +   GC + LI L+++N
Sbjct:   18 IWVSVDSNSFLKIFGTVSASAA-LQFVN--------VGYFLIAIGSLLVILGFLGCCGAQRESKCLLLTFFSIILIIFIAEVAGAVVALVYSSLAETILGPLLKPVLQNEY-----GSNPDVTKIWNSTMENLHCCGFNNYTDFS----NSTFYNNNHQQYPSYCC--------NSTSS----------ANSVCTQQGAMNSHV--SGCFSQLIYLIRQN 199
[Close]
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Tspan1 (tetraspanin 1 [Source:MGI Symbol;Acc:MGI:1914055])

HSP 1 Score: 60.4622 bits (145), Expect = 3.748e-10
Identity = 53/174 (30.46%), Postives = 82/174 (47.13%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCC 871
            GAA+L VGIWV VD ++  ++   +    S + F N        +   LI  GA  F+ GF GC GA  EN+ +L+ +  ++    IAEI   + A V        L+  +   I+KD+        T FT+++   M +L CCG  + +DFN +     +   K+   P  CC
Sbjct:   22 GAALLAVGIWVSVDGTSFLKVFGSLS--SSAMQFVN--------VGYFLIAAGAVLFILGFLGCYGAHSENKCVLMMFFSILLIIFIAEIAGAVVALVYTTLAEQFLTLLVVPAIEKDY-----GYQTDFTQVWNTTMEELHCCGFNNYTDFNASRF---VKENKVFPPP--CC 175
[Close]
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Tspan1 (tetraspanin 1 [Source:MGI Symbol;Acc:MGI:1914055])

HSP 1 Score: 60.8474 bits (146), Expect = 3.856e-10
Identity = 53/174 (30.46%), Postives = 82/174 (47.13%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCC 871
            GAA+L VGIWV VD ++  ++   +    S + F N        +   LI  GA  F+ GF GC GA  EN+ +L+ +  ++    IAEI   + A V        L+  +   I+KD+        T FT+++   M +L CCG  + +DFN +     +   K+   P  CC
Sbjct:   22 GAALLAVGIWVSVDGTSFLKVFGSLS--SSAMQFVN--------VGYFLIAAGAVLFILGFLGCYGAHSENKCVLMMFFSILLIIFIAEIAGAVVALVYTTLAEQFLTLLVVPAIEKDY-----GYQTDFTQVWNTTMEELHCCGFNNYTDFNASRF---VKENKVFPPP--CC 175
[Close]
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Tspan3 (tetraspanin 3 [Source:MGI Symbol;Acc:MGI:1928098])

HSP 1 Score: 57.3806 bits (137), Expect = 6.766e-9
Identity = 42/148 (28.38%), Postives = 75/148 (50.68%), Query Frame = 2 
Query:  443 VSFENTDNTVLDVI----AIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCK 874
            +++++ D+   DV     A+V+I  GA  F+ G  GCC  I+E+R  L T+  ++    + E+ + +   V   K  N++  S++  + K +NG    N+   ++    +   L CCGI + SD+   N +W     K QS P+ CC+
Sbjct:   39 ITYDDYDHFFEDVYTLFPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVFILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQK-VYKTYNG---TNSDAASRAIDYVQRQLHCCGIHNYSDWE--NTDW-FKETKNQSVPLSCCR 179
[Close]
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Tspan3 (tetraspanin 3 [Source:MGI Symbol;Acc:MGI:1928098])

HSP 1 Score: 56.9954 bits (136), Expect = 7.286e-9
Identity = 42/148 (28.38%), Postives = 75/148 (50.68%), Query Frame = 2 
Query:  443 VSFENTDNTVLDVI----AIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCK 874
            +++++ D+   DV     A+V+I  GA  F+ G  GCC  I+E+R  L T+  ++    + E+ + +   V   K  N++  S++  + K +NG    N+   ++    +   L CCGI + SD+   N +W     K QS P+ CC+
Sbjct:   36 ITYDDYDHFFEDVYTLFPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVFILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQK-VYKTYNG---TNSDAASRAIDYVQRQLHCCGIHNYSDWE--NTDW-FKETKNQSVPLSCCR 176
[Close]
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Cd82 (CD82 antigen [Source:MGI Symbol;Acc:MGI:104651])

HSP 1 Score: 56.9954 bits (136), Expect = 8.026e-9
Identity = 61/230 (26.52%), Postives = 105/230 (45.65%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLK--YEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRN 1033
            GA ILG G+W+  DK++   +L+             T ++ L V A V I  GA T V GF GC GA+ E R LL  Y + +   +IA++ +G+       K   ++ +++ ++I+       AN  +   + +  +   ++CCG V  S +N T  N  +      ++P  C K+      + Q  +K  + +  +  V+ N P +  VN E    GC+      L+ N
Sbjct:   24 GAVILGFGVWILADKNSFISVLQ-------------TSSSSLQVGAYVFIGVGAITIVMGFLGCIGAVNEVRCLLGLYFVFLLLILIAQVTVGVLFYFNADKLKKEMGNTVMDIIRN----YTANATSSREEAWDYVQAQVKCCGWV--SHYNWTE-NEELMGFTKTTYPCSCEKIKEE---DNQLIVKKGFCEADNSTVSENNPEDWPVNTE----GCMEKAQAWLQEN 226
[Close]
BLAST of Tetraspanin vs. UniProt/SwissProt
Match: sp|Q99J59|TSN1_MOUSE (Tetraspanin-1 OS=Mus musculus OX=10090 GN=Tspan1 PE=2 SV=1)

HSP 1 Score: 60.8474 bits (146), Expect = 2.697e-9
Identity = 53/174 (30.46%), Postives = 82/174 (47.13%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCC 871
            GAA+L VGIWV VD ++  ++   +    S + F N        +   LI  GA  F+ GF GC GA  EN+ +L+ +  ++    IAEI   + A V        L+  +   I+KD+        T FT+++   M +L CCG  + +DFN +     +   K+   P  CC
Sbjct:   22 GAALLAVGIWVSVDGTSFLKVFGSLS--SSAMQFVN--------VGYFLIAAGAVLFILGFLGCYGAHSENKCVLMMFFSILLIIFIAEIAGAVVALVYTTLAEQFLTLLVVPAIEKDY-----GYQTDFTQVWNTTMEELHCCGFNNYTDFNASRF---VKENKVFPPP--CC 175
[Close]
BLAST of Tetraspanin vs. UniProt/SwissProt
Match: sp|Q6AYR9|TSN1_RAT (Tetraspanin-1 OS=Rattus norvegicus OX=10116 GN=Tspan1 PE=2 SV=1)

HSP 1 Score: 59.3066 bits (142), Expect = 8.859e-9
Identity = 49/153 (32.03%), Postives = 75/153 (49.02%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFN 808
            GAA+L VGIWV VD ++  +    +    S + F N        +   LI  GA  F+ GF GC GA  EN+ +L+ +  ++    IAEI   + A V        L+  +   I+KD+        T+FT+++ + M  L CCG  + +DFN
Sbjct:   22 GAALLAVGIWVSVDGTSFLKAFGSL--SSSAMQFVN--------VGYFLIAAGAVLFILGFLGCYGAHSENKCVLMMFFSILLIIFIAEIAGAVVALVYTTMAEQFLTFLVVPAIEKDY-----GYQTEFTQVWNSTMEGLHCCGFNNYTDFN 159
[Close]
BLAST of Tetraspanin vs. UniProt/SwissProt
Match: sp|Q4R7W6|TSN1_MACFA (Tetraspanin-1 OS=Macaca fascicularis OX=9541 GN=TSPAN1 PE=2 SV=1)

HSP 1 Score: 58.5362 bits (140), Expect = 1.491e-8
Identity = 57/171 (33.33%), Postives = 89/171 (52.05%), Query Frame = 2 
Query:  293 CKSFSKXXXXXXXXXXXXXGAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDF 805
            C SF K I+I+FN+L F+ GAA+L VGIWV +D ++  +I   +    S + F N        +   LI  GA  F  GF GC GA  E++  L+T+  ++    IAE+   + A V      + L+  +   IKKD+      +   FT+++   M +L+CCG  + +DF
Sbjct:    3 CFSFIKTIMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLS--SSAMQFVN--------VGYFLIAAGAVVFALGFLGCYGAQTESKCALMTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAIKKDY-----GSQKDFTQVWNTTMTELKCCGFTNYTDF 158
[Close]
BLAST of Tetraspanin vs. UniProt/SwissProt
Match: sp|Q5RE11|TSN3_PONAB (Tetraspanin-3 OS=Pongo abelii OX=9601 GN=TSPAN3 PE=2 SV=1)

HSP 1 Score: 57.7658 bits (138), Expect = 2.869e-8
Identity = 58/233 (24.89%), Postives = 102/233 (43.78%), Query Frame = 2 
Query:  443 VSFENTDNTVLDVI----AIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFACIVARRKD*D 1129
            +++++ D+   DV     A+V+I  GA  F+ G  GCC  I+E+R  L T+ I++    + E+ + +   V   K  N++  S++  + K +NG    N    ++    +   L CCGI + SD+   N +W     K QS P+ CC+                        +NC        +L  +GC   ++K L+  +  VI   +     ++  +  ACIV  R+  D
Sbjct:   36 ITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQK-VYKTYNG---TNPDAASRAIDYVQRQLHCCGIHNYSDWE--NTDW-FKETKNQSVPLSCCRET---------------------ASNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD 240
[Close]
BLAST of Tetraspanin vs. UniProt/SwissProt
Match: sp|O60637|TSN3_HUMAN (Tetraspanin-3 OS=Homo sapiens OX=9606 GN=TSPAN3 PE=2 SV=1)

HSP 1 Score: 57.7658 bits (138), Expect = 2.869e-8
Identity = 58/233 (24.89%), Postives = 102/233 (43.78%), Query Frame = 2 
Query:  443 VSFENTDNTVLDVI----AIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFACIVARRKD*D 1129
            +++++ D+   DV     A+V+I  GA  F+ G  GCC  I+E+R  L T+ I++    + E+ + +   V   K  N++  S++  + K +NG    N    ++    +   L CCGI + SD+   N +W     K QS P+ CC+                        +NC        +L  +GC   ++K L+  +  VI   +     ++  +  ACIV  R+  D
Sbjct:   36 ITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQK-VYKTYNG---TNPDAASRAIDYVQRQLHCCGIHNYSDWE--NTDW-FKETKNQSVPLSCCRET---------------------ASNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD 240
[Close]
BLAST of Tetraspanin vs. TrEMBL
Match: A0A267FTC4 (Tetraspanin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig020731g3 PE=3 SV=1)

HSP 1 Score: 119.783 bits (299), Expect = 2.644e-27
Identity = 92/273 (33.70%), Postives = 149/273 (54.58%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSD-------VSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDF---NGAFANNATQ---FTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISS----GKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFACIVARR 1117
            GAAI+GV IWV V   ++F+++  +  +GSD       +S++++ +T++   A V++VFGA +F+ GFCGCCGAI+E+  LL  Y+  V+  +I EI  GI AGV   +   ++  +LK L    +   N A +N++     F+ +       + CCG+   SD    N  W  SS    GK    PV CCK+N   K    S+  +  I D L+  NCP+  + + ++NK+GC + L   + R    +I + I +G+FEI C+  AC + ++
Sbjct:   21 GAAIVGVSIWVIVSADSMFKLVH-LATQGSDNINNETLMSYKSSTSTLVAA-AYVILVFGALSFLIGFCGCCGAIRESSCLLSIYAGAVSIVLIVEIAGGIAAGVFRAQIGTEMLPTLKRLEATRYLPINLAVSNDSNPNAVFSSLVNYAQVSMSCCGVSSMSDITGVNTLWTNSSRQYNGKTIVVPVTCCKMNK--KDELLSHQNWTRIDDYLIDRNCPYNAS-SSQINKEGCYDKLNSYIDRYTLAIIVVGILVGMFEIICVVMACSMVQK 288
[Close]
BLAST of Tetraspanin vs. TrEMBL
Match: A0A267EG05 (Tetraspanin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig020731g1 PE=3 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 5.037e-27
Identity = 91/273 (33.33%), Postives = 149/273 (54.58%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSD-------VSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDF---NGAFANNATQ---FTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISS----GKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFACIVARR 1117
            GAAI+GV IWV V   ++F+++  +  +GSD       +S++++ +T++   A V++VFGA +F+ GFCGCCGAI+E+  LL  Y+  V+  +I EI  GI AGV   +   ++  +L+ L    +   N A +N++     F+ +       + CCG+   SD    N  W  SS    GK    PV CCK+N   K    S+  +  I D L+  NCP+  + + ++NK+GC + L   + R    +I + I +G+FEI C+  AC + ++
Sbjct:   21 GAAIVGVSIWVIVSADSMFKLVH-LATQGSDNINNETLMSYKSSTSTLVAA-AYVILVFGALSFLIGFCGCCGAIRESSCLLSIYAGAVSIVLIVEIAGGIAAGVFRAQIGTEMLPTLRRLEATRYLPINLAVSNDSNPNAVFSSLVNYAQVSMSCCGVSSMSDITGVNTLWTNSSRQYNGKTIVVPVTCCKMNK--KDELLSHQNWTRIDDYLIDRNCPYNAS-SSQINKEGCYDKLNSYIDRYTLAIIVVGILVGMFEIICVVMACSMVQK 288
[Close]
BLAST of Tetraspanin vs. TrEMBL
Match: A0A1I8GD10 (Tetraspanin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006680g1 PE=3 SV=1)

HSP 1 Score: 100.908 bits (250), Expect = 1.804e-20
Identity = 84/277 (30.32%), Postives = 137/277 (49.46%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKI--KIEGSD----VSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDF-------NGAFANNATQFTKIFTAIMFDLQCCG------IVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKY---EDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFACIVAR 1114
            GAA +GVGIWV V+KS+LF ++  I  +++  D    +      N ++ V   +LI  GAFT V GFCGCCGA+KE++ LL  Y+ LV   +  E+   I A V + +      D +  L +K F       + + ++N    T +   +     CCG      I + S + ++N +W    G+    P+ CC++  + K  A +   Y     +   LV  +CPF  T     +   C + ++  + +  G +IG+C G+ +FE+FCI  AC + R
Sbjct:   23 GAASVGVGIWVAVNKSDLFRVINLIDARVDQGDNKGQIDSVANQNGLVTVAGFILIGIGAFTLVVGFCGCCGAVKESKCLLGMYAFLVGLVLAVEVTAAILAAVYQARIRTAAEDGMYGLQEKMFVAMTDYLSDSTSDNNKTVTTLINYLQMSFDCCGAKKPGDIANSSSWLLSNRSW---EGRELQTPITCCQIRQDQK-TAAAAPGYNWVSKLNGTLVDPSCPFTGTTQ---HTKTCYSGIMDFIGKFAGPLIGVCAGIAVFELFCIIVACCLVR 292
[Close]
BLAST of Tetraspanin vs. TrEMBL
Match: A0A1I8I7N5 (Tetraspanin OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 2.854e-20
Identity = 78/235 (33.19%), Postives = 127/235 (54.04%), Query Frame = 2 
Query:  443 VSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDF---NGAFANNATQ---FTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISS----GKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFACIVARR 1117
            +S++++ +T++   A V++VFGA +F+ GFCGCCGAI+E+  LL  Y+  V+  +I EI  GI AGV   +   ++  +LK L    +   N A +N++     F+ +       + CCG+   SD    N  W  SS    GK    PV CCK+N   K    S+  +  I D L+  NCP+  + + ++NK+GC + L   + R    +I + I +G+FEI C+  AC + ++
Sbjct:   11 MSYKSSTSTLVAA-AYVILVFGALSFLIGFCGCCGAIRESSCLLSIYAGAVSIVLIVEIAGGIAAGVFRAQIGTEMLPTLKRLEATRYLPINLAVSNDSNPNAVFSSLVNYAQVSMSCCGVSSMSDITGVNTLWTNSSRQYNGKTIVVPVTCCKMNK--KDELLSHQNWTRIDDYLIDRNCPYNAS-SSQINKEGCYDKLNSYIDRYTLAIIVVGILVGMFEIICVVMACSMVQK 241
[Close]
BLAST of Tetraspanin vs. TrEMBL
Match: A0A267ERG2 (Tetraspanin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig023279g1 PE=3 SV=1)

HSP 1 Score: 100.523 bits (249), Expect = 3.088e-20
Identity = 86/278 (30.94%), Postives = 136/278 (48.92%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKI-------EGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDF-------NGAFANNATQFTKIFTAIMFDLQCCG------IVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKY---EDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFACIVAR 1114
            GAA +GVGIWV V+KS+LF ++  I         +G   S  N +  V+ V   +LI  GAFT V GFCGCCGA+KE++ LL  Y+ LV   +  E+   I A V + +      D +  L +K F       + + ++N    T +   +     CCG      I + S + ++N +W    G+    P+ CC++  + K  A +   Y     +   LV  +CPF  T     +   C + ++  + +  G +IG+C G+ +FE+FCI  AC + R
Sbjct:   23 GAASVGVGIWVAVNKSDLFRVINLIDARVDQGDNKGQIDSVANQNGLVM-VAGFILIGIGAFTLVVGFCGCCGAVKESKCLLGMYAFLVGLVLAVEVAAAILAAVYQARIRTAAEDGMYGLQEKMFVAMTDYLSDSTSDNNKTVTTLINYLQMSFDCCGAKKPGDIANSSSWLLSNRSW---EGRELQTPITCCQIRQDQK-TAAAAPGYNWVSKLNGTLVDPSCPFTGTTQ---HTKTCYSGIMDFIGKFAGPLIGVCAGIAVFELFCIIVACCLVR 292
[Close]
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: tspan18a (tetraspanin 18 [Source:NCBI gene;Acc:103047105])

HSP 1 Score: 68.9366 bits (167), Expect = 4.064e-13
Identity = 56/189 (29.63%), Postives = 81/189 (42.86%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLK 916
            GA +LGVGIWV VD +   EI+                N +L     V++  G   F+ GF GCCGAI+EN+ LL+  S  +                   K  N   D     +K  + G  +N+   FT  +  IM   +CCG+    DF+  +L   +   +L   P  CC+  N+L  N +  LK
Sbjct:   24 GAFLLGVGIWVLVDPTGFREIV--------------AANPLLFTGVYVILAMGGMLFLLGFLGCCGAIRENKCLLLFVSTFL-------------------KPENLRLDYFTKELKTYYQG--SNSTDVFTATWNTIMTTFECCGVNSADDFDQQSLFRRLYPSRLV--PEECCQ-RNDLLMNKEECLK 174
[Close]
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: tspan18a (tetraspanin 18 [Source:NCBI gene;Acc:103047105])

HSP 1 Score: 62.7734 bits (151), Expect = 6.515e-11
Identity = 58/189 (30.69%), Postives = 89/189 (47.09%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLK 916
            GA +LGVGIWV VD +   EI+                N +L     V++  G   F+ GF GCCGAI+EN+ LL+ + +L+    +AE+   I A +  +       D     +K  + G  +N+   FT  +  IM   +CCG+    DF+  +L   +   +L   P  CC+  N+L  N +  LK
Sbjct:   36 GAFLLGVGIWVLVDPTGFREIV--------------AANPLLFTGVYVILAMGGMLFLLGFLGCCGAIRENKCLLLFFFLLILIIFLAELAAAILAFIFREHLTR---DYFTKELKTYYQG--SNSTDVFTATWNTIMTTFECCGVNSADDFDQQSLFRRLYPSRLV--PEECCQ-RNDLLMNKEECLK 202
[Close]
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: cd63 (CD63 molecule [Source:NCBI gene;Acc:103032697])

HSP 1 Score: 61.6178 bits (148), Expect = 1.542e-10
Identity = 73/255 (28.63%), Postives = 111/255 (43.53%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFACIVAR 1114
            G A++ +G+WV+V       + +   I+G+  S             +VLI+ G   F   F GCCGA KEN  ++  ++IL++  +I EIG  I A V   K    + D L+++IK+     + N + ++ +    I  DL+CCG  + SD       W        S P  CCK   N+  +       +D   K+  T               GC  AL KLLK N+  V    I +   EI  + FAC + R
Sbjct:   25 GLALIVLGVWVQV------SLHKTPVIQGASGS----------AAPLVLIIVGVVIFFIAFFGCCGAWKENYCMVTMFAILLSLIIIVEIGTAIAAYVFRDKLTGLVDDGLRDMIKQ-----YNNGSKEYQEGLDRIQKDLKCCGAANSSD-------WVNFKPDHTSVPDSCCK---NVTADCGKGAMNDD--KKIYVT---------------GCQPALEKLLKENVQWVAVAAIVIAFIEILGLVFACSLMR 231
[Close]
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: cd63 (CD63 molecule [Source:NCBI gene;Acc:103032697])

HSP 1 Score: 61.2326 bits (147), Expect = 2.763e-10
Identity = 73/255 (28.63%), Postives = 111/255 (43.53%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFACIVAR 1114
            G A++ +G+WV+V       + +   I+G+  S             +VLI+ G   F   F GCCGA KEN  ++  ++IL++  +I EIG  I A V   K    + D L+++IK+     + N + ++ +    I  DL+CCG  + SD       W        S P  CCK   N+  +       +D   K+  T               GC  AL KLLK N+  V    I +   EI  + FAC + R
Sbjct:   46 GLALIVLGVWVQV------SLHKTPVIQGASGS----------AAPLVLIIVGVVIFFIAFFGCCGAWKENYCMVTMFAILLSLIIIVEIGTAIAAYVFRDKLTGLVDDGLRDMIKQ-----YNNGSKEYQEGLDRIQKDLKCCGAANSSD-------WVNFKPDHTSVPDSCCK---NVTADCGKGAMNDD--KKIYVT---------------GCQPALEKLLKENVQWVAVAAIVIAFIEILGLVFACSLMR 252
[Close]
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: tspan18b (tetraspanin-18-like [Source:NCBI gene;Acc:103035514])

HSP 1 Score: 58.9214 bits (141), Expect = 1.401e-9
Identity = 63/255 (24.71%), Postives = 115/255 (45.10%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGI-----VDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFA 1099
            G+ +LGVG+W+ VD ++  EI+                N +L     +++  G   F+ GF GCCGA++EN+ LL+ + + +    +AE+   I A +  +    +        ++K + G   N +   T  + AIM    CCG+      +ES F+V N +        Q  P  CC+ N++L   + SN      +D+ ++ N  +        N  GC ++++   +  + I   + I +   E+F + FA
Sbjct:   36 GSFLLGVGVWMLVDPTDFREIVAA--------------NPLLFTGVYIILAMGGMLFLLGFLGCCGALRENKCLLLFFFMFILVIFLAELATAILAFIFREHLTKE---YFTKELRKHYQG--YNTSDVLTTTWNAIMKTFDCCGVNSPEDFEESLFHVLNPS--------QVVPEACCRKNSHLGDVSFSN------KDECLSGNMLYR-------NNKGCYSSVVDYFEMYIYIAGALAIVVLTIELFAMIFA 250
[Close]
BLAST of Tetraspanin vs. Ensembl Sea Lamprey
Match: CD151 (CD151 molecule (Raph blood group) [Source:HGNC Symbol;Acc:HGNC:1630])

HSP 1 Score: 53.9138 bits (128), Expect = 1.470e-8
Identity = 48/177 (27.12%), Postives = 82/177 (46.33%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQ-FTKIFTAIMFDLQCCGIVDESDFNVTN-LNWAISSGKLQSHPVGCCK 874
            GA ++ VG+W  V+K +   +L       +  +F  T        A +LI+ G+   +TG  GCC  ++E R  L  Y  L+    + E+  GI A +    +  QLS+ LK+ + K    ++     Q  T     +  + +CCG  D +D+  ++ +  A + G+L   P  CCK
Sbjct:   32 GAGVMAVGVWTLVEKGDYLSLL-------ASSTFAAT--------AYILILAGSVVMLTGLLGCCAVVRERRGCLAAYCGLLLLIFLLEVIAGILAYL----YRQQLSEELKSHMNKTIVESYGQPDQQRVTDAMDKLQQEFKCCGSHDWNDWQRSDWVKVAAAEGRLV--PDSCCK 187
[Close]
BLAST of Tetraspanin vs. Ensembl Sea Lamprey
Match: tspan17 (tetraspanin 17 [Source:ZFIN;Acc:ZDB-GENE-030131-3673])

HSP 1 Score: 47.3654 bits (111), Expect = 1.947e-6
Identity = 67/259 (25.87%), Postives = 108/259 (41.70%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNV-TNLNWAISSGKLQ--SHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKD------GCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFA 1099
            GAA L +G+W   +K  L  +     ++G D  +             + IV G   F+ GF GC GA++EN  LL  +S  +      E+  G+ A V +    +QL+  + N +K   +     N   F + +       QCCG     D++     N +I +   +    P  CC                +D  + +V T C ++  +  EL++       GC+    K L+ NL +V GI IG+ L +IF I  A
Sbjct:   15 GAAFLAIGLWAWAEKGVLSNLSSITDLKGFDPVW-------------LFIVVGTVMFILGFAGCIGALRENTYLLKFFSTFLGLIFFLELTAGVLAFVFKDWLRDQLNFFIYNNVKAYRDDIDLQNLIDFAQDY------WQCCGAHGPLDWDENIYFNCSIKNRSREKCGVPFSCC---------------VKDPAEDVVNTQCGYDVRLKTELDQQSYIYTKGCVTQFEKWLQNNLILVAGIFIGIALVQIFGICLA 239
[Close]
BLAST of Tetraspanin vs. Ensembl Nematostella
Match: EDO30837 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZN5])

HSP 1 Score: 56.6102 bits (135), Expect = 2.731e-9
Identity = 77/279 (27.60%), Postives = 127/279 (45.52%), Query Frame = 2 
Query:  281 KMGFCKSFSKXXXXXXXXXXXXXGAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVEL--NKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFACIVA 1111
            K+G C    K +L  FN LF+++G ++L VGIW ++  S+       +K+   D +            A +LI  G    + GF GCCGA+KE+  LL T+ +++    + E+G  I   +   +    LSD L   +K      F +      K       +L+CCG  + +D+ +  + WA  + K  S P  CCK                D + K    +C  E   + E   ++ GC  A +K  +  L I+ G+ +GL +F++  IAF+C +A
Sbjct:    5 KLGACMQCVKFLLFGFNALFWLMGLSVLAVGIWARIQFSDY------MKLSSHDYA----------TAAYILIGIGFLIAIIGFIGCCGALKEHTCLLKTFGVILGLLFLVELGTAITGYIFRSEIKTGLSDGLDTALKDYPEQGFKDAWNDMQK-------NLKCCGSRNYTDWFM--VAWAGPNTKNGSVPESCCK----------------DTKVK----SCNLEVLSHPETINSEQGCYGAAVKYFEDKLVIIGGVALGLAVFQLIGIAFSCCLA 238
[Close]
BLAST of Tetraspanin vs. Ensembl Nematostella
Match: EDO35938 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK25])

HSP 1 Score: 53.9138 bits (128), Expect = 2.294e-8
Identity = 57/253 (22.53%), Postives = 104/253 (41.11%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFV--NQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFAC 1102
            G A+LG+GIW KVD       L                ++   + A  +I  GAF    GF GCCGA+KE+R +L T+   +   +++         +  K F+  +Q+ + +K  + +     +  ++   + I   +   L+CCG     D+      W     K +  P+ CC  N N                    T C  + T   E+   GC+N L   + +++ ++  I +G+ + ++  + F+C
Sbjct:   22 GLAVLGIGIWTKVDAGQFDSFL---------------GSSGYSIPAWTMIGAGAFVTFVGFFGCCGAVKESRCMLATWLKYLLTILLSLSKQVNLFELYLKFFLLWHQVQEEIKINLDEQIRNTYGYDSEVESHI-NNLQIRLKCCGGERPGDW--LGSKWKRDLNKDKIVPLSCCTENAN-------------------KTTCYKDDTYK-EVYSSGCVNELKTFVDKHMILIGAIAVGISIVQLLGMIFSC 236
[Close]
BLAST of Tetraspanin vs. Ensembl Nematostella
Match: EDO42387 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1M8])

HSP 1 Score: 49.6766 bits (117), Expect = 8.444e-7
Identity = 44/152 (28.95%), Postives = 71/152 (46.71%), Query Frame = 2 
Query:  464 NTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQS--HPVGCCK----LNNNLKYNA 901
            +++L   ++V+++ G   F+    GC GA++EN ILL  Y   V   +I  +  GI   +   K V +L D LK+    D           F  +   +  +L+CCG+   +D+  TN+ +  SS   +S   P  CCK    LN    Y+A
Sbjct:   75 DSILYEPSVVILIVGILLFLIATVGCIGALRENTILLAIYGGAVTLCLIFLVSAGIAVYMHRDKVVEKLKDDLKHYRDPD--------KENFQFLIDRLQTNLKCCGVNSYTDWQ-TNIYFNCSSPGSESCGVPFSCCKESIQLNRQCGYDA 217
[Close]
BLAST of Tetraspanin vs. Ensembl Nematostella
Match: EDO35917 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK24])

HSP 1 Score: 48.1358 bits (113), Expect = 1.905e-6
Identity = 48/175 (27.43%), Postives = 75/175 (42.86%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCK 874
            G A++ VGIW +V  +    ++                 +     A ++I  GA     GF GCCGA+KEN+  L+ Y  L+    + EI  GI A  +  K ++ +  +L   I  D+     +N  + TK         +CCG   +   +  N  WA S+   Q+ P  CCK
Sbjct:   24 GIAVMSVGIWTRVSANEYASLM---------------GQSGFTAAANIMIAAGALVMFIGFVGCCGAVKENKCFLLLYFFLLLVIFVLEIASGILAYTKRDKVISSVEKALNQSISLDYG---QSNKEKATKAVDRAQSIFKCCG-ATQGPKDWANTAWAKSNTN-QTVPESCCK 178
[Close]
BLAST of Tetraspanin vs. Ensembl Nematostella
Match: EDO41430 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S484])

HSP 1 Score: 46.9802 bits (110), Expect = 4.157e-6
Identity = 46/159 (28.93%), Postives = 73/159 (45.91%), Query Frame = 2 
Query:  449 FENTDN--TVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQS--HPVGCCK----LNNNLKYNA 901
            F+N  N  ++L   ++V+++ G   F+    GC GA++EN ILL  Y   V   +I  +  G    +   K V +L D L++    D           F  +   +  +L+CCGI   +D+  TN+ +  SS   +S   P  CCK    LN    Y+A
Sbjct:   31 FKNAWNLDSILYEPSVVILIVGILLFLIATVGCIGALRENTILLAIYGGAVTLCLILLVSAGTAVYIHRDKVVAKLKDDLQHYRDPD--------KENFQFLIDRLQTNLKCCGINSYNDWQ-TNVYFNCSSPGSESCGVPFSCCKESIQLNRQCGYDA 180
[Close]
BLAST of Tetraspanin vs. Ensembl Medaka
Match: tspan34 (tetraspanin-1 [Source:NCBI gene;Acc:101174246])

HSP 1 Score: 72.0182 bits (175), Expect = 4.678e-14
Identity = 59/199 (29.65%), Postives = 99/199 (49.75%), Query Frame = 2 
Query:  293 CKSFSKXXXXXXXXXXXXXGAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNT-VLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNN 886
            C  F K+++ IFN   F+ GA  LG+GIW+KVD  +L  +L  I         EN D    L  +A VLI  GA   + GF GCCGA+KE+R +L+T+   +   +      G           +++ D+++N ++      F  + +  T ++ + M   +CCG  + +DF  +  N  + SG+   +P  CC  +++
Sbjct:    3 CSGFLKVMMFIFNGGIFLAGAGCLGMGIWLKVDSGSLLGLLEGI---------ENGDGLDQLVHVAYVLIGVGAALVIIGFLGCCGAVKESRCMLLTF-FCIVLVIFIVEVAGAIVLFAFDGLADKILDNVENEVRSKLQTEFGRDES-LTSVWGSTMEQFKCCGYRNYTDFTGSPFN--VVSGE---YPSPCCGRSSD 185
[Close]
BLAST of Tetraspanin vs. Ensembl Medaka
Match: tspan35 (tetraspanin-1 [Source:NCBI gene;Acc:101164063])

HSP 1 Score: 69.707 bits (169), Expect = 3.947e-13
Identity = 72/205 (35.12%), Postives = 107/205 (52.20%), Query Frame = 2 
Query:  278 SKMGFCKSFSKXXXXXXXXXXXXXGAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQF------TKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCK 874
            ++MG C  F KI++ IFN + F+ GAAILGVGIWVKVD S++   L K+    S+       N VL+V   +LI  GA   + GF GCCGA KEN+ +L+ + I++    IAE+   I         +      + NL++K    A A+   ++      T ++ + M  LQCCG  + SDFN ++        K + +P  CC 
Sbjct:   18 TEMG-CFGFLKIMMFIFNGIIFLAGAAILGVGIWVKVDSSSILGFLGKLPDAPSEF------NQVLNV-GYLLIAIGALLVLIGFLGCCGASKENKCMLLLFFIIILLVFIAEVAGAIV--------ILAFRPLVDNLLQKASVNAVASIQMEYGKNPDLTGLWNSTMTTLQCCGFNNYSDFNNSDY-----YNKTKGYPPQCCS 201
[Close]
BLAST of Tetraspanin vs. Ensembl Medaka
Match: tspan18b (tetraspanin 18 [Source:NCBI gene;Acc:101168705])

HSP 1 Score: 62.003 bits (149), Expect = 1.313e-10
Identity = 68/260 (26.15%), Postives = 113/260 (43.46%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGI-----VDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFACIVAR 1114
            G+ +LGVG+WV VD +   EI+                N +L     V++  G   F+ GF GCCGAI+EN+ LL+ + +L+    +AE+   I A +  +    +        +K+ + G   NN   FT  + AIM    CCG+       +S F + N N  +        P  CC     L+ +    L Y   +D+ ++ N  F        N  GC +A++   +  + +   + I +   E+F + FA  + R
Sbjct:   36 GSFLLGVGVWVLVDPTGFREIV--------------AANPLLFTGVYVILGMGGMLFLLGFLGCCGAIRENKCLLLFFFMLILLIFLAELAAAILAFIFREHLTREY---FTKELKRHYQG--YNNTDVFTSTWNAIMTTFDCCGVNSPEDFKDSRFRLINPNHVV--------PEACC-----LRVSQNGELAYTS-RDQCLSGNMMFR-------NNKGCYSAVVDYFELYIYVAGALAIVVLTIELFAMVFAMCLFR 255
[Close]
BLAST of Tetraspanin vs. Ensembl Medaka
Match: tspan3b (tetraspanin-3 [Source:NCBI gene;Acc:101165292])

HSP 1 Score: 59.6918 bits (143), Expect = 6.981e-10
Identity = 59/233 (25.32%), Postives = 103/233 (44.21%), Query Frame = 2 
Query:  443 VSFENTDNTVLDVI----AIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFACIVARRKD*D 1129
            +S+++ D+   DV     A+V+I  G   F+ G  GCC  I+E+   L T++ ++    + E  + +   +   K  +Q++ S    I+K +N     N+   ++    +   L CCGI + SD+   N +W I S K  S PV CC+ N                      +NC    T   +L ++GC   ++K LK  +  VI   +     ++  +  AC+V  R+  D
Sbjct:   36 ISYDDYDHFFEDVYTLIPAVVIIAVGTLLFIIGLIGCCATIRESSCGLATFAAILLLVFVTECVVVVLGYIYRAKVEDQVNHS----IQKVYNEYSGINSDAPSRAIDYVQKQLHCCGIHNYSDWR--NTHWFIES-KNNSVPVSCCQPN---------------------ISNCTGTLTRPGDLYQEGCEALVVKKLKEIMMYVIWAALTFASIQMLGMLCACVVLCRRGHD 240
[Close]
BLAST of Tetraspanin vs. Ensembl Medaka
Match: tspan18b (tetraspanin 18 [Source:NCBI gene;Acc:101168705])

HSP 1 Score: 58.9214 bits (141), Expect = 1.500e-9
Identity = 62/231 (26.84%), Postives = 100/231 (43.29%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGI-----VDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLK 1027
            G+ +LGVG+WV VD +   EI+                N +L     V++  G   F+ GF GCCGAI+EN+ LL+ + +L+    +AE+   I A +  +    +        +K+ + G   NN   FT  + AIM    CCG+       +S F + N N  +        P  CC     L+ +    L Y   +D+ ++ N  F        N  GC +A++   +
Sbjct:   36 GSFLLGVGVWVLVDPTGFREIV--------------AANPLLFTGVYVILGMGGMLFLLGFLGCCGAIRENKCLLLFFFMLILLIFLAELAAAILAFIFREHLTREY---FTKELKRHYQG--YNNTDVFTSTWNAIMTTFDCCGVNSPEDFKDSRFRLINPNHVV--------PEACC-----LRVSQNGELAYTS-RDQCLSGNMMFR-------NNKGCYSAVVDYFE 226
[Close]
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000078589.1 (SMESG000078589.1)

HSP 1 Score: 444.891 bits (1143), Expect = 1.309e-157
Identity = 278/280 (99.29%), Postives = 278/280 (99.29%), Query Frame = 2 
Query:  284 MGFCKSFSKXXXXXXXXXXXXXGAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFACIVARRKD 1123
            MGFCKSFSKIILIIFNVLFFIIGAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSILVAAAVIAEIGIGIYAGVEEKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNW ISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLK NLGIVIGICIGLGLFEIFCIAFACIVARRKD
Sbjct:    1 MGFCKSFSKIILIIFNVLFFIIGAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSILVAAAVIAEIGIGIYAGVEEKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWTISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKENLGIVIGICIGLGLFEIFCIAFACIVARRKD 280
[Close]
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000019443.1 (SMESG000019443.1)

HSP 1 Score: 228.794 bits (582), Expect = 7.912e-73
Identity = 145/281 (51.60%), Postives = 205/281 (72.95%), Query Frame = 2 
Query:  284 MGFCKSFSKXXXXXXXXXXXXXGAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAIS-SGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFACIVARRKD 1123
            M FC+S +K++LIIFN+ FF+IGA ILG+GIWVK+DKSNLFE+LR IK+E +  SF+NT++++ D IAI LIV GA TF+TGFCGCCGAIKE++ LL  YS+ V   ++ +IG+GIYAGV++ K    L  SL ++++ +FNG  + N + FTK  TAIMF+++CCGI +E+DF +T  NW  +  G+ Q HP+GCCK+  +  +++++ L Y  + D LV   CP   T   +LN +GCI+ LI+ ++ NL IVI +C+GLGLFE+ CI FAC VARR +
Sbjct:    1 MSFCESIAKLLLIIFNICFFLIGALILGIGIWVKIDKSNLFEMLRNIKLEETASSFDNTNSSLFDTIAIFLIVLGAITFITGFCGCCGAIKESQCLLFLYSLFVTVVIVGQIGVGIYAGVQKNKVQYYLESSLVSVLENEFNGIISPNPSMFTKALTAIMFEMKCCGIRNENDFKITKQNWKQTIQGQNQVHPIGCCKIKQSFSFDSENKLNYTILSDILVDPLCP--VTKATKLNYEGCISVLIEKIRNNLTIVISVCVGLGLFEMLCIVFACCVARRNN 279
[Close]
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000078545.1 (SMESG000078545.1)

HSP 1 Score: 213.001 bits (541), Expect = 1.320e-66
Identity = 151/282 (53.55%), Postives = 198/282 (70.21%), Query Frame = 2 
Query:  284 MGFCKSFSKXXXXXXXXXXXXXGAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNW-AISSGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETT-VNVELNKDGCINALIKLLKRNXXXXXXXXXXXXXFEIFCIAFACIVARRKD 1123
            MG C+SFSK +LIIFNVLFFI+G   LGVGIWVKVDKSNLFEI+RK+ ++G+  SF+++ ++ L+++AIVLIV G FTF+ GFCGCCGAIKEN  LL  YS LV   ++ E+GIGIYAGVE+ KF N +  +L  ++K +FNG  + NAT FTK+FTA+M +L+CCGI D+ DFN T +NW  I   K Q++P+GCC       YN       + ++      +CP  T     +LN  GC  +LI L+ +NLGIVIG+C+GLGLFEIFCI FAC V  +K 
Sbjct:    1 MGCCESFSKTLLIIFNVLFFILGGVFLGVGIWVKVDKSNLFEIMRKVNLDGTASSFDSSSSSFLNIVAIVLIVLGTFTFIIGFCGCCGAIKENHCLLYLYSFLVGVVILIEVGIGIYAGVEKGKFKNGIDQALTKILKSEFNGIMSPNATIFTKVFTAVMLELKCCGIKDQEDFNSTKVNWRQIIDNKTQANPIGCCAEKEVYVYNTNDKFVLDKVKPFFKNPDCPTTTNRTQAKLNPTGCSQSLIDLINKNLGIVIGVCVGLGLFEIFCIIFACCVISKKS 282
[Close]
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000019444.1 (SMESG000019444.1)

HSP 1 Score: 209.149 bits (531), Expect = 2.773e-65
Identity = 112/229 (48.91%), Postives = 165/229 (72.05%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAIS-SGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRN 1033
            GA ILGVGIWVKVDKSNLFE++R I ++ +  SF +T++++ D++AI+LI+ GAFTF+TGFCGCCGAIKE+  LL  YS LVAA ++A++ +GIYA V++ KF  +L  SL  ++ KDFNGA ++N + FTK+FTA+MF+++CCG+  E+DFN     W  + SG+ Q HP+GCCKL N+  +N++  L    +++ +   NC FE     +LN+ GC+ +LI  +K +
Sbjct:   23 GAVILGVGIWVKVDKSNLFEMMRNINLDETAKSFSSTNSSLFDIVAIILIILGAFTFITGFCGCCGAIKESSCLLFMYSFLVAAVIVAQVAVGIYASVQQNKFQARLEKSLIKIVAKDFNGALSSNPSMFTKVFTALMFEMKCCGVKGEADFNGIGDAWKQTISGRKQIHPIGCCKLKNSFHFNSKEKLNLTVVENTIEDPNCIFEK--ETKLNQKGCVVSLIDKIKSH 249
[Close]
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000019444.1 (SMESG000019444.1)

HSP 1 Score: 209.149 bits (531), Expect = 7.113e-62
Identity = 112/229 (48.91%), Postives = 165/229 (72.05%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAIS-SGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRN 1033
            GA ILGVGIWVKVDKSNLFE++R I ++ +  SF +T++++ D++AI+LI+ GAFTF+TGFCGCCGAIKE+  LL  YS LVAA ++A++ +GIYA V++ KF  +L  SL  ++ KDFNGA ++N + FTK+FTA+MF+++CCG+  E+DFN     W  + SG+ Q HP+GCCKL N+  +N++  L    +++ +   NC FE     +LN+ GC+ +LI  +K +
Sbjct:   23 GAVILGVGIWVKVDKSNLFEMMRNINLDETAKSFSSTNSSLFDIVAIILIILGAFTFITGFCGCCGAIKESSCLLFMYSFLVAAVIVAQVAVGIYASVQQNKFQARLEKSLIKIVAKDFNGALSSNPSMFTKVFTALMFEMKCCGVKGEADFNGIGDAWKQTISGRKQIHPIGCCKLKNSFHFNSKEKLNLTVVENTIEDPNCIFEK--ETKLNQKGCVVSLIDKIKSH 249

HSP 2 Score: 207.608 bits (527), Expect = 2.222e-61
Identity = 111/229 (48.47%), Postives = 165/229 (72.05%), Query Frame = 2 
Query:  350 GAAILGVGIWVKVDKSNLFEILRKIKIEGSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITYSXXXXXXXXXXXXXXXXXXXXXKKFVNQLSDSLKNLIKKDFNGAFANNATQFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAIS-SGKLQSHPVGCCKLNNNLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRN 1033
            GA ILGVGIWVKVDKSNLFE++R I ++ +  SF +T++++ D++AI+LI+ GAFTF+TGFCGCCGAIKE+  LL  YS LVAA ++A++ +GIYA V++ KF  +L  SL  ++ KDFNGA ++N + FTK+FTA+MF+++CCG+  E+DFN     W  + +G+ Q HP+GCCKL N+  +N++  L    +++ +   NC FE     +LN+ GC+ +LI  +K +
Sbjct:  336 GAVILGVGIWVKVDKSNLFEMMRNINLDETAKSFSSTNSSLFDIVAIILIILGAFTFITGFCGCCGAIKESSCLLFMYSFLVAAVIVAQVAVGIYASVQQNKFQARLEKSLIKIVAKDFNGALSSNPSMFTKVFTALMFEMKCCGVKGEADFNGIGDAWKQTINGRKQIHPIGCCKLKNSFHFNSKEKLNLTVVENTMEDPNCIFEK--ETKLNQKGCVVSLIDKIKSH 562
The following BLAST results are available for this feature:
BLAST of Tetraspanin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TSPAN35.975e-924.89tetraspanin 3 [Source:HGNC Symbol;Acc:HGNC:17752][more]
TSPAN12.901e-827.53tetraspanin 1 [Source:HGNC Symbol;Acc:HGNC:20657][more]
CD821.082e-738.46CD82 molecule [Source:HGNC Symbol;Acc:HGNC:6210][more]
CD821.282e-738.46CD82 molecule [Source:HGNC Symbol;Acc:HGNC:6210][more]
CD822.557e-728.85CD82 molecule [Source:HGNC Symbol;Acc:HGNC:6210][more]
back to top
BLAST of Tetraspanin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
tsp-111.998e-930.00Tetraspanin [Source:UniProtKB/TrEMBL;Acc:Q17526][more]
tsp-111.998e-930.00Tetraspanin [Source:UniProtKB/TrEMBL;Acc:Q17526][more]
back to top
BLAST of Tetraspanin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Tsp66E1.265e-1129.67gene:FBgn0035936 transcript:FBtr0076507[more]
Tsp66E1.265e-1129.67gene:FBgn0035936 transcript:FBtr0076506[more]
Tsp66E1.265e-1129.67gene:FBgn0035936 transcript:FBtr0076508[more]
Tsp26A1.629e-627.97gene:FBgn0031760 transcript:FBtr0307300[more]
back to top
BLAST of Tetraspanin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tspan341.243e-1229.78tetraspanin 34 [Source:ZFIN;Acc:ZDB-GENE-060825-20... [more]
tspan353.336e-1028.88tetraspanin 35 [Source:ZFIN;Acc:ZDB-GENE-040426-13... [more]
tspan18a2.959e-929.14tetraspanin 18a [Source:ZFIN;Acc:ZDB-GENE-040718-2... [more]
cd151l3.436e-927.53CD151 antigen, like [Source:ZFIN;Acc:ZDB-GENE-0404... [more]
tspan18a3.526e-929.14tetraspanin 18a [Source:ZFIN;Acc:ZDB-GENE-040718-2... [more]
back to top
BLAST of Tetraspanin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cd827.714e-1030.16CD82 molecule [Source:NCBI gene;Acc:394799][more]
wdr748.519e-1026.29WD repeat domain 74 [Source:Xenbase;Acc:XB-GENE-96... [more]
cd821.187e-930.16CD82 molecule [Source:NCBI gene;Acc:394799][more]
gpr881.366e-827.38G protein-coupled receptor 88 [Source:Xenbase;Acc:... [more]
tspan11.943e-725.00tetraspanin 1 [Source:NCBI gene;Acc:548861][more]
back to top
BLAST of Tetraspanin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tspan13.748e-1030.46tetraspanin 1 [Source:MGI Symbol;Acc:MGI:1914055][more]
Tspan13.856e-1030.46tetraspanin 1 [Source:MGI Symbol;Acc:MGI:1914055][more]
Tspan36.766e-928.38tetraspanin 3 [Source:MGI Symbol;Acc:MGI:1928098][more]
Tspan37.286e-928.38tetraspanin 3 [Source:MGI Symbol;Acc:MGI:1928098][more]
Cd828.026e-926.52CD82 antigen [Source:MGI Symbol;Acc:MGI:104651][more]
back to top
BLAST of Tetraspanin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q99J59|TSN1_MOUSE2.697e-930.46Tetraspanin-1 OS=Mus musculus OX=10090 GN=Tspan1 P... [more]
sp|Q6AYR9|TSN1_RAT8.859e-932.03Tetraspanin-1 OS=Rattus norvegicus OX=10116 GN=Tsp... [more]
sp|Q4R7W6|TSN1_MACFA1.491e-833.33Tetraspanin-1 OS=Macaca fascicularis OX=9541 GN=TS... [more]
sp|Q5RE11|TSN3_PONAB2.869e-824.89Tetraspanin-3 OS=Pongo abelii OX=9601 GN=TSPAN3 PE... [more]
sp|O60637|TSN3_HUMAN2.869e-824.89Tetraspanin-3 OS=Homo sapiens OX=9606 GN=TSPAN3 PE... [more]
back to top
BLAST of Tetraspanin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267FTC42.644e-2733.70Tetraspanin OS=Macrostomum lignano OX=282301 GN=BO... [more]
A0A267EG055.037e-2733.33Tetraspanin OS=Macrostomum lignano OX=282301 GN=BO... [more]
A0A1I8GD101.804e-2030.32Tetraspanin OS=Macrostomum lignano OX=282301 GN=BO... [more]
A0A1I8I7N52.854e-2033.19Tetraspanin OS=Macrostomum lignano OX=282301 PE=3 ... [more]
A0A267ERG23.088e-2030.94Tetraspanin OS=Macrostomum lignano OX=282301 GN=BO... [more]
back to top
BLAST of Tetraspanin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tspan18a4.064e-1329.63tetraspanin 18 [Source:NCBI gene;Acc:103047105][more]
tspan18a6.515e-1130.69tetraspanin 18 [Source:NCBI gene;Acc:103047105][more]
cd631.542e-1028.63CD63 molecule [Source:NCBI gene;Acc:103032697][more]
cd632.763e-1028.63CD63 molecule [Source:NCBI gene;Acc:103032697][more]
tspan18b1.401e-924.71tetraspanin-18-like [Source:NCBI gene;Acc:10303551... [more]
back to top
BLAST of Tetraspanin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CD1511.470e-827.12CD151 molecule (Raph blood group) [Source:HGNC Sym... [more]
tspan171.947e-625.87tetraspanin 17 [Source:ZFIN;Acc:ZDB-GENE-030131-36... [more]
back to top
BLAST of Tetraspanin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Tetraspanin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO308372.731e-927.60Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO359382.294e-822.53Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO423878.444e-728.95Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO359171.905e-627.43Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO414304.157e-628.93Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Tetraspanin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tspan344.678e-1429.65tetraspanin-1 [Source:NCBI gene;Acc:101174246][more]
tspan353.947e-1335.12tetraspanin-1 [Source:NCBI gene;Acc:101164063][more]
tspan18b1.313e-1026.15tetraspanin 18 [Source:NCBI gene;Acc:101168705][more]
tspan3b6.981e-1025.32tetraspanin-3 [Source:NCBI gene;Acc:101165292][more]
tspan18b1.500e-926.84tetraspanin 18 [Source:NCBI gene;Acc:101168705][more]
back to top
BLAST of Tetraspanin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000078589.11.309e-15799.29SMESG000078589.1[more]
SMESG000019443.17.912e-7351.60SMESG000019443.1[more]
SMESG000078545.11.320e-6653.55SMESG000078545.1[more]
SMESG000019444.12.773e-6548.91SMESG000019444.1[more]
SMESG000019444.17.113e-6248.91SMESG000019444.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010326 ID=SMED30010326|Name=Tetraspanin|organism=Schmidtea mediterranea sexual|type=transcript|length=1154bp
TTTAATGAAACTATCCAAAATTAAATGCAAAATTTCACGAGAATTTTATT
AGTTAAGAACCAACAAAACCTTTTATTGCGTAATTTGACTCGTTCAGTGC
AATATTTTCAACTGCATTTGATAATGTAGAATATTTAATGAATAACCATA
GCATTAACATTTCCATTGATTTATTTATAATTTCTCTATCACATATGCTC
AACATTCGTCAGCCAATCAAATTGCTTTGAAAATAATTTGACATAAAAAC
CTTGAATTTGCTTTGTTATCACAAGTTTCGAAAATGGGTTTCTGCAAATC
ATTTTCTAAAATTATTTTGATTATTTTCAACGTCCTTTTTTTTATAATTG
GTGCTGCAATTCTCGGGGTTGGAATATGGGTTAAAGTAGACAAATCGAAT
TTGTTTGAAATTTTAAGGAAAATCAAAATTGAAGGCTCAGATGTATCGTT
TGAAAATACAGACAACACGGTTCTTGACGTGATAGCTATTGTTCTTATCG
TTTTTGGAGCTTTTACATTTGTTACTGGTTTTTGCGGCTGTTGTGGAGCA
ATTAAGGAAAACAGAATTTTACTAATTACGTATTCAATCTTAGTTGCTGC
AGCTGTTATTGCTGAAATTGGGATTGGGATTTATGCTGGAGTTGAAGAGA
AAAAATTTGTCAATCAATTAAGTGATTCATTGAAAAATTTGATAAAGAAG
GATTTTAATGGCGCCTTTGCAAATAATGCAACGCAATTTACGAAAATTTT
CACAGCTATTATGTTTGATTTACAATGTTGTGGAATAGTTGATGAAAGTG
ATTTTAATGTTACCAATTTAAATTGGGCTATTAGTTCCGGGAAATTGCAA
TCCCACCCAGTTGGATGCTGTAAATTAAATAATAATCTCAAATACAATGC
TCAATCAAATTTAAAATATGAAGATATACAAGACAAATTAGTTACTACGA
ATTGCCCATTTGAAACTACTGTCAATGTGGAATTAAACAAAGATGGCTGC
ATAAATGCTTTAATTAAGTTACTAAAAAGGAATTTAGGTATTGTTATTGG
AATTTGCATTGGCCTTGGTTTATTTGAAATATTTTGTATTGCATTTGCAT
GCATCGTGGCGAGAAGAAAGGATTAAGATTTGAATTGTTTGACTGATTAT
TATT
back to top

protein sequence of SMED30010326-orf-1

>SMED30010326-orf-1 ID=SMED30010326-orf-1|Name=SMED30010326-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=281bp
MGFCKSFSKIILIIFNVLFFIIGAAILGVGIWVKVDKSNLFEILRKIKIE
GSDVSFENTDNTVLDVIAIVLIVFGAFTFVTGFCGCCGAIKENRILLITY
SILVAAAVIAEIGIGIYAGVEEKKFVNQLSDSLKNLIKKDFNGAFANNAT
QFTKIFTAIMFDLQCCGIVDESDFNVTNLNWAISSGKLQSHPVGCCKLNN
NLKYNAQSNLKYEDIQDKLVTTNCPFETTVNVELNKDGCINALIKLLKRN
LGIVIGICIGLGLFEIFCIAFACIVARRKD*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000014zeta neoblast
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000026gut
PLANA:0000420parapharyngeal region
PLANA:0000429neoblast
Vocabulary: INTERPRO
TermDefinition
IPR000301Tetraspanin
IPR018499Tetraspanin/Peripherin
IPR008952Tetraspanin_EC2_sf
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000301TetraspaninPRINTSPR00259TMFOURcoord: 253..279
score: 23.25
coord: 64..90
score: 38.53
coord: 10..33
score: 37.77
coord: 91..119
score: 26.34
IPR000301TetraspaninPIRSFPIRSF002419Tetraspanincoord: 1..280
e-value: 4.5E-39
score: 131.7
IPR018499Tetraspanin/PeripherinPFAMPF00335Tetraspanincoord: 9..277
e-value: 4.9E-41
score: 140.9
NoneNo IPR availablePANTHERPTHR19282TETRASPANINcoord: 9..273
NoneNo IPR availablePANTHERPTHR19282:SF283TETRASPANIN-21coord: 9..273
NoneNo IPR availableTMHMMTMhelixcoord: 11..33
NoneNo IPR availableTMHMMTMhelixcoord: 253..275
NoneNo IPR availableTMHMMTMhelixcoord: 66..88
NoneNo IPR availableTMHMMTMhelixcoord: 95..117
IPR008952Tetraspanin, EC2 domain superfamilySUPERFAMILYSSF48652Tetraspanincoord: 127..251