slc22a-11
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30010312 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of slc22a-11 vs. Ensembl Human
Match: SLC22A2 (solute carrier family 22 member 2 [Source:HGNC Symbol;Acc:HGNC:10966]) HSP 1 Score: 88.9669 bits (219), Expect = 7.975e-18 Identity = 109/527 (20.68%), Postives = 208/527 (39.47%), Query Frame = 2
Query: 653 MFLYYTPKYQCLSPNQTTDSI-----------------------TPDNCFYVPVNSSLAKFPC----TKWKFDKSKIK--------------STFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQIL---NQNSEDEDFNNKSIDDTETVHENKRF---CHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYS------IIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIY---GILLIISMILF----------GLIIPSINKTSLPNTVEEAEQIKKDSQ 2029
+FL +TP ++C SP S+ +P C V+ + + F C ++S++ S+ VTE LVC ++ + N+ G F ++ +G ++D GRK L + +L+ I P++ + IF L +IG +L+TE ++YR + I Y +++G+ + +W+ + P F + L + ESP+WLIS ++ EA +++ + N S +++ N F + + IL+ + +YQG ++ A +IY++ L+E PA ++ + I + W +++ + IPG+ Q KI I++CL + + +A+ I+ + L+PT RN + + D GG +Y I L + +++F L++P +LP T+EEAE +++ +
Sbjct: 41 VFLGFTPDHRCRSPGVAELSLRCGWSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVDPLASLDTNRSRLPLGPCRDGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVNV-GFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIFYQVAYTVGLLVLAGVAYALPHWRWLQFTVSLPNFFFLLYYWCIPESPRWLISQNKNAEAMRIIKHIAKKNGKSLPASLQRLRLEEETGKKLNPSFLDLVRTPQIRKHTMILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPA---AFMIILTIDRIGRRYPWAASNMVAGAACLASVFIPGD-------LQWLKI---IISCLGRMGITMAYEIVCLVNAELYPTFIRNLGVHICSSMC----------------DIGGIITPFLVYRLTNIWLELPLMVFGVLGLVAGGLVLLLPETKGKALPETIEEAENMQRPRK 537
BLAST of slc22a-11 vs. Ensembl Human
Match: SLC22A1 (solute carrier family 22 member 1 [Source:HGNC Symbol;Acc:HGNC:10963]) HSP 1 Score: 85.5001 bits (210), Expect = 1.145e-16 Identity = 98/454 (21.59%), Postives = 186/454 (40.97%), Query Frame = 2
Query: 746 NSSLAKFPCTK-WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF-AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSED---EDFNNKSIDDTETVHENKRFC---HSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIG----LISYSIIPG-NWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLI---ISMILFG----------LIIPSINKTSLPNTVEEAEQIKKDSQ 2029
S L PC W +D S+ VTE LVC + + N +F ++ +G +D GRK L + + +L+ P++ S+ +F L G+ + G L+TE R + I Y F++G+ +W+ L + P FL+ L + ESP+WL+S R EA +++ + Q + D S+++ T + F + L R IL+ + +YQG ++ ++Y++ + L+EIP + ++ +G + + + + L+ I P +W LN+ I+ C+ + + +A ++ + L+PT FV N G D GG ++ + + + +ILF L++P +LP T+++AE + + ++
Sbjct: 113 RSHLPLGPCQDGWVYDTPG--SSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFISPDLHW---LNI---------IIMCVGRMGITIAIQMICLVNAELYPT----FVRNLGVMVCSSLC------------DIGGIITPFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAK 536
BLAST of slc22a-11 vs. Ensembl Human
Match: SLC22A3 (solute carrier family 22 member 3 [Source:HGNC Symbol;Acc:HGNC:10967]) HSP 1 Score: 85.5001 bits (210), Expect = 1.257e-16 Identity = 105/451 (23.28%), Postives = 192/451 (42.57%), Query Frame = 2
Query: 746 NSSLAKFPCTK-WKFDKSKIKSTFVTELKLVCNQRF---LQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIK-LFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVL-QILNQNSEDEDFNNKSIDDTETVHENKRF---CHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGS----VTSVVIWTTIGLISYSIIPG-NWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIY----GILLIISMILFG----------LIIPSINKTSLPNTVEEAEQI 2014
N S PC W++ ++ ST V+E LVC + L ++ L ++G F LG +D GR ++L+ + +++ P ++ + + RF++ +FG G+ + V+VTE+ K R + I F++G+ + P W+ L P FL+ L ++ ESP+WLI+ + D+A ++L +I N + N I T+ N F + + IL+ + VYQG L ++YI+ I G++E+P L L+ +G S ++ L++ + G W + +A L + + +A+ I+ + L+PT RNF + D GG A F+ + L + +I+FG +++P +LP TV++ E++
Sbjct: 119 NRSAPLVPCRGGWRYAQAH--STIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFT--LGYAADRYGRIVIYLLSCLGVGVTGVVVAFAP-NFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRWLITRKKGDKALQILRRIAKCNGKYLSSNYSEITVTDEEVSNPSFLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLPFAASNIVAGVACLVTAFLPEGIAW------------LRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLC----------------DFGGI-IAPFLLFRLAAVWLELPLIIFGILASICGGLVMLLPETKGIALPETVDDVEKL 535
BLAST of slc22a-11 vs. Ensembl Human
Match: SLC22A16 (solute carrier family 22 member 16 [Source:HGNC Symbol;Acc:HGNC:20302]) HSP 1 Score: 84.7297 bits (208), Expect = 1.746e-16 Identity = 100/443 (22.57%), Postives = 188/443 (42.44%), Query Frame = 2
Query: 593 LIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPN--QTTDSITPDNC----------FYVPVNSSLAKFPCTK-WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIG---MAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQIL---NQNSEDEDFNNKSID--------DTETVHENKRFCH-----SKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFG 1819
++YFI + G+ + S+F+ TP + C P Q + C S +FPC + +D++ KST VT+ LVC++++L ++ PL + GV ++ G SD GR+ + S S + I +Y+ F+ + G ++G V V E K R + ++ S F++G +A+T + ++ + ++ P L +L E+P WL+S R +EA +++ I+ N+ S + S+D TE N + +K L I SL FY + + NL + Y+N ++G++EIPA ++ +G T + ++ ++ + + Q I + A + KF++ A+ ++ ++ L+PT R+ G
Sbjct: 20 VLYFICAFQNISCGIHYLASVFMGVTPHHVCRPPGNLQNGEIWELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTWKSTAVTQWNLVCDRKWLAMLIQPLF-MFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLVALTGYLVRTWWLYQMILSTVTVPFI---LCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGSLGFY-SFSLNSVNLG---GNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFCSALACGVV-------MVIPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSG 447
BLAST of slc22a-11 vs. Ensembl Human
Match: SLC22A1 (solute carrier family 22 member 1 [Source:HGNC Symbol;Acc:HGNC:10963]) HSP 1 Score: 81.2629 bits (199), Expect = 2.188e-15 Identity = 85/373 (22.79%), Postives = 158/373 (42.36%), Query Frame = 2
Query: 746 NSSLAKFPCTK-WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF-AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSED---EDFNNKSIDDTETVHENKRFC---HSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIG----LISYSIIPG-NWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEA 1825
S L PC W +D S+ VTE LVC + + N +F ++ +G +D GRK L + + +L+ P++ S+ +F L G+ + G L+TE R + I Y F++G+ +W+ L + P FL+ L + ESP+WL+S R EA +++ + Q + D S+++ T + F + L R IL+ + +YQG ++ ++Y++ + L+EIP + ++ +G + + + + L+ I P +W LN+ I+ C+ + + +A ++ + L+PT FV+ G A
Sbjct: 113 RSHLPLGPCQDGWVYDTPG--SSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFISPDLHW---LNI---------IIMCVGRMGITIAIQMICLVNAELYPT----FVSGVGPA 467
BLAST of slc22a-11 vs. Ensembl Celegans
Match: K05F1.6 (pep chromosome:WBcel235:II:5782942:5787658:1 gene:WBGene00019408.1 transcript:K05F1.6a.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K05F1.6) HSP 1 Score: 65.0846 bits (157), Expect = 1.348e-10 Identity = 117/475 (24.63%), Postives = 193/475 (40.63%), Query Frame = 2
Query: 761 KFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLG-ILSDMKGRKPMFLICSGSDTIIWILLGI-LP--SHYSLHIFLRFIK-LFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQI--------LNQNSEDEDFNNKSIDDTETVHENKRFCHSKS-------LLIRLGILLITSLSFYFVYQGTAT---NLEFAISD------------IYINAMIMGLIEIPA-------GPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRN-------FVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILL-IISMILFGL----------IIPSINKTSLPNTVEEA 2005
K C + F+K + T VT+ LVC+ F + +I + LG I SD GRKP +I G I+ +LG+ LP +Y + + +R + + + + L E+T KYR + + +++G A+ WK +IAA F+ + + ESP+WL+ +R EA EV++ N + + N S D E V +R + K+ L + L ++S V+ TA L A+SD ++N I G IEIP LG ++ + +TS + I + S++ G++ L GKI ++ A+NIL +F L+PT RN VA FG +G S+ + I L I+ MI+F + ++P ++ LP T+++A
Sbjct: 325 KKKCQAYHFEKDVMVETIVTDFNLVCDSWFAKGHAHMFYSIGYLLGCVLGGIASDKIGRKPT-IIGFG---ILSSMLGVFLPFNDYYPMFLLIRLLSAICNEAADLAAYTLCMEITGTKYRAMVGSMLQAPWALGYALLALIAYLTKSWKTIQVIAAGLHFMSIIFICSIPESPRWLMVQNRVSEAEEVIRKACREPPFPFNMCTTSKCGNLPS--DLELVSHRERKLNKKNGGKIGFLDLFTMKELRYRTISVCIVFMATALVYYGLVMALSDQSAPGRTLFTGYFHLNNGIAGAIEIPTLFACVWMMQLGRKKALMLTLITSGLF---IIVAMLSMVSGHYMLALAFMYFGKI-----------AVQGAFNILYIFTSELYPTVVRNTAVGVTSMVARFG---------------------SGLSSYIALLSNISLPIVPMIIFAVFSLFAGMLVFVLPETSEKPLPETLDDA 758
BLAST of slc22a-11 vs. Ensembl Celegans
Match: K05F1.6 (pep chromosome:WBcel235:II:5782524:5787658:1 gene:WBGene00019408.1 transcript:K05F1.6a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K05F1.6) HSP 1 Score: 65.0846 bits (157), Expect = 1.348e-10 Identity = 117/475 (24.63%), Postives = 193/475 (40.63%), Query Frame = 2
Query: 761 KFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLG-ILSDMKGRKPMFLICSGSDTIIWILLGI-LP--SHYSLHIFLRFIK-LFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQI--------LNQNSEDEDFNNKSIDDTETVHENKRFCHSKS-------LLIRLGILLITSLSFYFVYQGTAT---NLEFAISD------------IYINAMIMGLIEIPA-------GPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRN-------FVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILL-IISMILFGL----------IIPSINKTSLPNTVEEA 2005
K C + F+K + T VT+ LVC+ F + +I + LG I SD GRKP +I G I+ +LG+ LP +Y + + +R + + + + L E+T KYR + + +++G A+ WK +IAA F+ + + ESP+WL+ +R EA EV++ N + + N S D E V +R + K+ L + L ++S V+ TA L A+SD ++N I G IEIP LG ++ + +TS + I + S++ G++ L GKI ++ A+NIL +F L+PT RN VA FG +G S+ + I L I+ MI+F + ++P ++ LP T+++A
Sbjct: 325 KKKCQAYHFEKDVMVETIVTDFNLVCDSWFAKGHAHMFYSIGYLLGCVLGGIASDKIGRKPT-IIGFG---ILSSMLGVFLPFNDYYPMFLLIRLLSAICNEAADLAAYTLCMEITGTKYRAMVGSMLQAPWALGYALLALIAYLTKSWKTIQVIAAGLHFMSIIFICSIPESPRWLMVQNRVSEAEEVIRKACREPPFPFNMCTTSKCGNLPS--DLELVSHRERKLNKKNGGKIGFLDLFTMKELRYRTISVCIVFMATALVYYGLVMALSDQSAPGRTLFTGYFHLNNGIAGAIEIPTLFACVWMMQLGRKKALMLTLITSGLF---IIVAMLSMVSGHYMLALAFMYFGKI-----------AVQGAFNILYIFTSELYPTVVRNTAVGVTSMVARFG---------------------SGLSSYIALLSNISLPIVPMIIFAVFSLFAGMLVFVLPETSEKPLPETLDDA 758
BLAST of slc22a-11 vs. Ensembl Celegans
Match: K05F1.6 (pep chromosome:WBcel235:II:5782942:5787658:1 gene:WBGene00019408.1 transcript:K05F1.6c.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K05F1.6) HSP 1 Score: 65.0846 bits (157), Expect = 1.421e-10 Identity = 117/475 (24.63%), Postives = 193/475 (40.63%), Query Frame = 2
Query: 761 KFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLG-ILSDMKGRKPMFLICSGSDTIIWILLGI-LP--SHYSLHIFLRFIK-LFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQI--------LNQNSEDEDFNNKSIDDTETVHENKRFCHSKS-------LLIRLGILLITSLSFYFVYQGTAT---NLEFAISD------------IYINAMIMGLIEIPA-------GPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRN-------FVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILL-IISMILFGL----------IIPSINKTSLPNTVEEA 2005
K C + F+K + T VT+ LVC+ F + +I + LG I SD GRKP +I G I+ +LG+ LP +Y + + +R + + + + L E+T KYR + + +++G A+ WK +IAA F+ + + ESP+WL+ +R EA EV++ N + + N S D E V +R + K+ L + L ++S V+ TA L A+SD ++N I G IEIP LG ++ + +TS + I + S++ G++ L GKI ++ A+NIL +F L+PT RN VA FG +G S+ + I L I+ MI+F + ++P ++ LP T+++A
Sbjct: 327 KKKCQAYHFEKDVMVETIVTDFNLVCDSWFAKGHAHMFYSIGYLLGCVLGGIASDKIGRKPT-IIGFG---ILSSMLGVFLPFNDYYPMFLLIRLLSAICNEAADLAAYTLCMEITGTKYRAMVGSMLQAPWALGYALLALIAYLTKSWKTIQVIAAGLHFMSIIFICSIPESPRWLMVQNRVSEAEEVIRKACREPPFPFNMCTTSKCGNLPS--DLELVSHRERKLNKKNGGKIGFLDLFTMKELRYRTISVCIVFMATALVYYGLVMALSDQSAPGRTLFTGYFHLNNGIAGAIEIPTLFACVWMMQLGRKKALMLTLITSGLF---IIVAMLSMVSGHYMLALAFMYFGKI-----------AVQGAFNILYIFTSELYPTVVRNTAVGVTSMVARFG---------------------SGLSSYIALLSNISLPIVPMIIFAVFSLFAGMLVFVLPETSEKPLPETLDDA 760
BLAST of slc22a-11 vs. Ensembl Celegans
Match: K05F1.6 (pep chromosome:WBcel235:II:5782524:5787658:1 gene:WBGene00019408.1 transcript:K05F1.6c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K05F1.6) HSP 1 Score: 65.0846 bits (157), Expect = 1.421e-10 Identity = 117/475 (24.63%), Postives = 193/475 (40.63%), Query Frame = 2
Query: 761 KFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLG-ILSDMKGRKPMFLICSGSDTIIWILLGI-LP--SHYSLHIFLRFIK-LFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQI--------LNQNSEDEDFNNKSIDDTETVHENKRFCHSKS-------LLIRLGILLITSLSFYFVYQGTAT---NLEFAISD------------IYINAMIMGLIEIPA-------GPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRN-------FVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILL-IISMILFGL----------IIPSINKTSLPNTVEEA 2005
K C + F+K + T VT+ LVC+ F + +I + LG I SD GRKP +I G I+ +LG+ LP +Y + + +R + + + + L E+T KYR + + +++G A+ WK +IAA F+ + + ESP+WL+ +R EA EV++ N + + N S D E V +R + K+ L + L ++S V+ TA L A+SD ++N I G IEIP LG ++ + +TS + I + S++ G++ L GKI ++ A+NIL +F L+PT RN VA FG +G S+ + I L I+ MI+F + ++P ++ LP T+++A
Sbjct: 327 KKKCQAYHFEKDVMVETIVTDFNLVCDSWFAKGHAHMFYSIGYLLGCVLGGIASDKIGRKPT-IIGFG---ILSSMLGVFLPFNDYYPMFLLIRLLSAICNEAADLAAYTLCMEITGTKYRAMVGSMLQAPWALGYALLALIAYLTKSWKTIQVIAAGLHFMSIIFICSIPESPRWLMVQNRVSEAEEVIRKACREPPFPFNMCTTSKCGNLPS--DLELVSHRERKLNKKNGGKIGFLDLFTMKELRYRTISVCIVFMATALVYYGLVMALSDQSAPGRTLFTGYFHLNNGIAGAIEIPTLFACVWMMQLGRKKALMLTLITSGLF---IIVAMLSMVSGHYMLALAFMYFGKI-----------AVQGAFNILYIFTSELYPTVVRNTAVGVTSMVARFG---------------------SGLSSYIALLSNISLPIVPMIIFAVFSLFAGMLVFVLPETSEKPLPETLDDA 760
BLAST of slc22a-11 vs. Ensembl Celegans
Match: B0361.11 (Putative transporter B0361.11 [Source:UniProtKB/Swiss-Prot;Acc:Q7Z118]) HSP 1 Score: 58.9214 bits (141), Expect = 8.091e-9 Identity = 88/358 (24.58%), Postives = 152/358 (42.46%), Query Frame = 2
Query: 797 KIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAI-FLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYS--LHIFLRFIKLFGIGSSI---IGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILL-ESPKWLISNSRKDEAFEVLQILNQ-NSEDEDFNN-KSIDDTETVHEN-KRFCHSKSLL--------IRLGILLIT-SLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIW----TTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRN 1801
K + + + L C+ F Q + + I V A+ F+ +L+D GRKP+ + T I L + + +S IFL G S + V E +K R +I + Y +S+GM T W+ + I + P +YG A L ESP WLI+ ++ ++ + ++ N+ N+ +FN+ + E HE+ K SK L+ I + I L+ ++SF V G F S LIEIPAG L + + +VIW T+ LI ++ +++ L + K+ +I+ +++ ++ FPT+ R+
Sbjct: 127 KASTNLLVDFDLSCSHWFFQEFGLTIFTIGAVIAVPFMSMLADRYGRKPIIVT-----TAILAFLANMAASFSPNFAIFLILRAFIGACSDSYLSVASVATCEYLSEKARAWITVVYNVAWSLGMVWTLLVTLMTDDWRWRYFIVSLPG-VYGFALWYFLPESPHWLITKNKTEKLKKYIKTANRVNNVSPEFNDCQQSSHHEEKHESFKALLGSKKLIWLLFANGFIEMVISLVYFAISFMSVELGGDQVQAFLYS---------SLIEIPAG-LAVIPLMMKMGRKMIVIWCLVFQTLALIGVTVFLDSYEFKLVIMLVAKVMATII-----------YSVHPIWATEQFPTSVRS 457
BLAST of slc22a-11 vs. Ensembl Fly
Match: Orct (gene:FBgn0019952 transcript:FBtr0334870) HSP 1 Score: 84.7297 bits (208), Expect = 9.606e-17 Identity = 104/452 (23.01%), Postives = 182/452 (40.27%), Query Frame = 2
Query: 596 IYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSP--NQTTDSITP----------DNCFYVPVN------------SSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPL----ILLESPKWLISNSRKDEAFEVLQILNQNSEDE---DFNNKSIDDTETVHENKRFCHSKSL-----LIRLGILLITSLSFYF-------VYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGS---VTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILAC--LSKFSLVVAWNILSVFYVALFPTNKRN 1801
IY+++ + +FL P ++C P N + ++P + C Y V+ SS C+ + +D+SK ++ VTE LVC++ L L + GV ++ G +SD GRKP F I +L + P ++S I + G ++ V+ E+ YR F + FS+G +T FAY+ W + L GL L I+ ES +WL+ RKDEAF +++ + ++ E + + +D+ + S+ L+R L +L +F VY G + N + +N MI G +EIP L + G + ++ I L++ +P + + + I+AC + K ++ ++ + +F FPT RN
Sbjct: 20 IYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCSRSLLSATSDSLFML-GVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLT----AGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFVPSDMNWL------------IVACAMIGKLAITSSYGTIYIFSAEQFPTVVRN 454
BLAST of slc22a-11 vs. Ensembl Fly
Match: Orct (gene:FBgn0019952 transcript:FBtr0084599) HSP 1 Score: 84.7297 bits (208), Expect = 9.606e-17 Identity = 104/452 (23.01%), Postives = 182/452 (40.27%), Query Frame = 2
Query: 596 IYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSP--NQTTDSITP----------DNCFYVPVN------------SSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPL----ILLESPKWLISNSRKDEAFEVLQILNQNSEDE---DFNNKSIDDTETVHENKRFCHSKSL-----LIRLGILLITSLSFYF-------VYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGS---VTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILAC--LSKFSLVVAWNILSVFYVALFPTNKRN 1801
IY+++ + +FL P ++C P N + ++P + C Y V+ SS C+ + +D+SK ++ VTE LVC++ L L + GV ++ G +SD GRKP F I +L + P ++S I + G ++ V+ E+ YR F + FS+G +T FAY+ W + L GL L I+ ES +WL+ RKDEAF +++ + ++ E + + +D+ + S+ L+R L +L +F VY G + N + +N MI G +EIP L + G + ++ I L++ +P + + + I+AC + K ++ ++ + +F FPT RN
Sbjct: 20 IYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCSRSLLSATSDSLFML-GVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLT----AGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFVPSDMNWL------------IVACAMIGKLAITSSYGTIYIFSAEQFPTVVRN 454
BLAST of slc22a-11 vs. Ensembl Fly
Match: Orct2 (gene:FBgn0086365 transcript:FBtr0084598) HSP 1 Score: 84.7297 bits (208), Expect = 1.042e-16 Identity = 119/484 (24.59%), Postives = 198/484 (40.91%), Query Frame = 2
Query: 566 EEIINLRLF-----LIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSIT----------PDN--CFYVPVN------------SSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVT-----ELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPL----ILLESPKWLISNSRKDEAFEVLQ-----------------ILNQNSEDEDFNNKSIDDTETVHEN------KRFCH----SKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGS---VTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILAC--LSKFSLVVAWNILSVFYVALFPTNKRN 1801
E II+L F +IYF+I ++ +FL P ++C P + S P+N C Y V+ SS C+ + +D+SK ++ VTE LVC + F+ L + GV +I G LSD GRKP+ + +L G+ P +++ + F R + +G++ G+ LV E+ R + I FS+G +T FAY+ W + L GL + I+ ES +WL+ RKD A +Q +L++ E+ + ++D E + E FC+ K+LLI L L+ + VY G + N ++ +N +I G +EIPA L+ G + ++ + L++ IIP ++ I+AC L K ++ ++ + +F FPT RN
Sbjct: 5 EAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCGRDFMAATSDSLFML-GVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFT-YTFARLM----VGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLT----AVFAYFVHDWRWLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGENSEEKAKQKLEDQE-LDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSG-----VYYGLSWNTSNLGGNVLLNFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIP------------QRMHTLIVACAMLGKLAITASYGTVYIFSAEQFPTVVRN 460
BLAST of slc22a-11 vs. Ensembl Fly
Match: Orct2 (gene:FBgn0086365 transcript:FBtr0334869) HSP 1 Score: 84.7297 bits (208), Expect = 1.042e-16 Identity = 119/484 (24.59%), Postives = 198/484 (40.91%), Query Frame = 2
Query: 566 EEIINLRLF-----LIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSIT----------PDN--CFYVPVN------------SSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVT-----ELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPL----ILLESPKWLISNSRKDEAFEVLQ-----------------ILNQNSEDEDFNNKSIDDTETVHEN------KRFCH----SKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGS---VTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILAC--LSKFSLVVAWNILSVFYVALFPTNKRN 1801
E II+L F +IYF+I ++ +FL P ++C P + S P+N C Y V+ SS C+ + +D+SK ++ VTE LVC + F+ L + GV +I G LSD GRKP+ + +L G+ P +++ + F R + +G++ G+ LV E+ R + I FS+G +T FAY+ W + L GL + I+ ES +WL+ RKD A +Q +L++ E+ + ++D E + E FC+ K+LLI L L+ + VY G + N ++ +N +I G +EIPA L+ G + ++ + L++ IIP ++ I+AC L K ++ ++ + +F FPT RN
Sbjct: 5 EAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCGRDFMAATSDSLFML-GVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFT-YTFARLM----VGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLT----AVFAYFVHDWRWLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGENSEEKAKQKLEDQE-LDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSG-----VYYGLSWNTSNLGGNVLLNFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIP------------QRMHTLIVACAMLGKLAITASYGTVYIFSAEQFPTVVRN 460
BLAST of slc22a-11 vs. Ensembl Fly
Match: CG17752 (gene:FBgn0038718 transcript:FBtr0083779) HSP 1 Score: 83.1889 bits (204), Expect = 2.667e-16 Identity = 112/498 (22.49%), Postives = 193/498 (38.76%), Query Frame = 2
Query: 665 YTPKYQCLSPNQTTDSITPD--NCFYVPVNSSLAKF---PCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNI-SGVFAIFLGILSDMKGRKPMFLICS---GSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSS-IIGLVLVTELTPKKYRNFIIINYWSVF-SIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDT------ETVHENKRFCHSKSLLIRLG------------ILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAG--------PLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNF-VANFGEATXXXXXXXXXXXXXXXSNDNGGF--SFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQFCF 2038
+TP ++C +P + + +C + + + F C+ W FDK + TEL+ VC+ + + I S + +IF G L+D GR P ++ + S +G LP + F RFI + + ++ +LV E ++R F + VF SIG+ ++PW W+ A+ P + PL L ES +WL++ + D+A L+ + + FN + ++D+ + E KS +G ILLI S+ + + N+E + G + +P G +G + I T G + ++ P N+ +L + CL++F VVA++ + + + PT+ R VAN G F + + LLII L L +P LP T+EE E K ++ F
Sbjct: 43 FTPSHRCSAPVEEFSQNFTELLSCSVIQYDVDMTSFRDNKCSSWDFDKESNYESITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLP----MFSFTRFISGLSMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYSIGLMISPWIAIWLGNWRSYLWAASLPALGMLIFPLFLHESVEWLLTKGKFDKAVNNLKSVAK------FNGRQVEDSVFDEFIKHYREKLNSAQKKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFVVLPGGLSIILFQNKIGRKGMACASLLVGAFITATTGYLVGTLDPANYSVLLGF----------MVCLARFGAVVAYDAEAQYAAEIIPTSVRGRGVANIHVVGNAFAFFSSYIIYL------GTFYKPLPSLLISFLLIIGACL-CLTLPETLHKQLPQTLEEGEIFAKGEKWYF 513
BLAST of slc22a-11 vs. Ensembl Zebrafish
Match: slc22a2 (solute carrier family 22 member 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2167]) HSP 1 Score: 95.9005 bits (237), Expect = 3.384e-20 Identity = 113/463 (24.41%), Postives = 198/463 (42.76%), Query Frame = 2
Query: 719 PDNCFYVPVNSSLAKFPCTK-WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISG-VFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGI-GSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQ-ILNQNSED-----EDFNNKSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGS----VTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLI---ISMILFG----------LIIPSINKTSLPNTVEEAEQIKKDSQ 2029
PD F S + C W++D + +FVTE LVC + + +I V +I +G L+D GR FL+ + + IL+ P++ SL +F R + FG+ G ++G VL+TEL +R + + Y FS+G+ + P W+ ++ P + + ESP+WL++ ++ EA E+ + I +N + E + +ID T F +K L IL + VYQG L ++Y++ +I G++E+PA L L+ IG T+ ++ LI+ + IP D M L S +AC+ + + +A+ ++ L+PT RN + D GG +Y + +I + +I+FG L++P LP T+++ E ++ +
Sbjct: 105 PDGDFNQSQLSVMPMMSCVDGWEYDYVG-RQSFVTEFDLVCGDAWYVDMFQATLSIGFLVGSIAIGYLADKYGRMKSFLMTNFFIGVTGILVATSPNYISLLVF-RALFGFGVKGGWMVGYVLITELVGVDHRRTVGVTYQLFFSMGILLLPLLAYFITNWRWLQVVFTVPYICFLTYYWFIPESPRWLLTQNKIAEAVEITKSIAKENRKTLSKKIETLKDDNIDSGSTASFMDLFKTAK-LRTYTFILSFNWFTSAVVYQGLIMRLGILGGNVYVDFLISGIVELPAAFLILLTIERIGRRLPFATANIVAGAACLIT-AFIP---DSMFWL-------KSAVACVGRLGITMAFEMVVFVNTELYPTVIRNLGVSVCSTLC----------------DVGGIVAPFLLYRLAVIWLELPLIIFGALAFVAGGLVLLLPETKGVPLPETIDDIEHPNRNKE 537
BLAST of slc22a-11 vs. Ensembl Zebrafish
Match: zmp:0000001102 (zmp:0000001102 [Source:ZFIN;Acc:ZDB-GENE-140106-62]) HSP 1 Score: 90.1225 bits (222), Expect = 2.276e-18 Identity = 123/507 (24.26%), Postives = 210/507 (41.42%), Query Frame = 2
Query: 605 IISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGI-GSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDT-ETVHENKRFCHSKSLLIRL------GILLITSLSFYFV---YQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIG---SVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKR-------NFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQI--KKDSQFCFTESI 2050
I+SV + G MF + P++Q L + ++ ++ C W FD S ST T+ LVC++R L + + GV A+F G+L D GR+ M L+ S +I++ + S Y + RF+ + G S I +VL E K+R F+ + +SIG + + W+ +I P+FL + +S +WLI+N + + A++ L ++ DF ++ +T TV HS + L + + L T + +Y V Y G + N+ D Y+ I IE+PA L Y S +G + T ++ T ++ I P + +++A L K ++ + ++ L+PT R NF+A G + + + I+ + I I+ L++P N SLP TVE+ E + KK SQ F ++I
Sbjct: 69 IVSVPAQEDGTPASCHMFAH--PQFQLLINSSSSSALPVVEC-------------QNGWHFDNSTFISTLATQFDLVCDKRGLAKASATIFFV-GVMCGAVFFGVLCDKYGRRSMLLV-SYVFSIVFSVTSAFSSSYIMFAAFRFLTGLALTGISNISVVLSIEWVDTKHRTFMGLFGSMSWSIGNMLLAGFAFMVTDWRLLIVIVTAPLFLATATWWWIPDSARWLIANGKTETAYKYLHKCATFNQRLDFTSRVKPETLSTVVTVDHRGHSYTYLDLVKTPQLRKLTLFTGIVWYGVASTYYGISLNITGFGLDPYLTHFIYAAIEVPAKILVYFSLNKVGRRNTQTGTLVLTGFCILINIITPTEYWTF----------RTVIAVLGKGLSEASFTTVILYTTELYPTVMRQNGLGFTNFMARMGASISPLIMLLEDIWKL----------LPEVIFCSMAIFCGII-ALLLPETNNASLPETVEDIEDMRYKKFSQSTFCDTI 537
BLAST of slc22a-11 vs. Ensembl Zebrafish
Match: BX005258.3 (zmp:0000001102 [Source:NCBI gene;Acc:100000058]) HSP 1 Score: 89.7373 bits (221), Expect = 3.178e-18 Identity = 123/507 (24.26%), Postives = 210/507 (41.42%), Query Frame = 2
Query: 605 IISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGI-GSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDT-ETVHENKRFCHSKSLLIRL------GILLITSLSFYFV---YQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIG---SVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKR-------NFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQI--KKDSQFCFTESI 2050
I+SV + G MF + P++Q L + ++ ++ C W FD S ST T+ LVC++R L + + GV A+F G+L D GR+ M L+ S +I++ + S Y + RF+ + G S I +VL E K+R F+ + +SIG + + W+ +I P+FL + +S +WLI+N + + A++ L ++ DF ++ +T TV HS + L + + L T + +Y V Y G + N+ D Y+ I IE+PA L Y S +G + T ++ T ++ I P + +++A L K ++ + ++ L+PT R NF+A G + + + I+ + I I+ L++P N SLP TVE+ E + KK SQ F ++I
Sbjct: 69 IVSVPAQEDGTPASCHMFAH--PQFQLLINSSSSSALPVVEC-------------QNGWHFDNSTFISTLATQFDLVCDKRGLAKASATIFFV-GVMCGAVFFGVLCDKYGRRSMLLV-SYVFSIVFSVTSAFSSSYIMFAAFRFLTGLALTGISNISVVLSIEWVDTKHRTFMGLFGSMSWSIGNMLLAGFAFMVTDWRLLIVIVTAPLFLATATWWWIPDSARWLIANGKTETAYKYLHKCATFNKRLDFTSRVKPETLSTVVTVDHRGHSYTYLDLVKTPQLRKLTLFTGIVWYGVASTYYGISLNITGFGLDPYLTHFIYAAIEVPAKILVYFSLNKVGRRNTQTGTLVLTGFCILINIITPTEYWTF----------RTVIAVLGKGLSEASFTTVILYTTELYPTVMRQNGLGFTNFMARMGASISPLIMLLEDIWKL----------LPEVIFCSMAIFCGII-ALLLPETNNASLPETVEDIEDMRYKKFSQSTFCDTI 537
BLAST of slc22a-11 vs. Ensembl Zebrafish
Match: slc22a7a (solute carrier family 22 member 7a [Source:ZFIN;Acc:ZDB-GENE-050506-52]) HSP 1 Score: 87.4261 bits (215), Expect = 1.992e-17 Identity = 89/299 (29.77%), Postives = 139/299 (46.49%), Query Frame = 2
Query: 746 NSSLAKFPCTK-WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF-AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGI-GSSIIGLVLVTELTPKKYRNF---IIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNK-SIDDTE--TVHENKRFCHSKSLLIR---LGILLITSLSFYFVYQGTATNLEFAIS----DIYINAMIMGLIEIPAGPLGYLSSIAIG 1594
N S PC W +D+S+ ST TE LVC+ + L L I A+ G LSD GRKPM + S + I+ S Y + R + F + G SI + L E T K+R F II WSV ++ +A+ + I+ W+ L+ P + +A + ES +WL++N R +EA + L + + + K I++ + T+ E+ HS L+R L +++ S F+F T + F I+ +IY+ I G+IE+PA YL+ IG
Sbjct: 108 NRSNVSVPCQNGWVYDRSQFTSTTATEWDLVCDNKKLNQALATFFFIGVTMGAVVFGQLSDKFGRKPMIQVSFVSSAVFGIIEA-FSSSYVMFAIARTLCGFALTGMSITTVALCVEWTDVKHRTFTGTIISLGWSVGNMLLALLAYLIRD---WRHLILVVTSPCLVGIIAWWWIPESARWLLANGRVEEAQKYLINCAKMNGKYSYTKKLDIENLKKITIAEDSNKNHSYLDLVRTPKLRKIVLCSGIFWFAVAFTYYGISFNITGFGLNIYLTQFIYGVIEVPAKVGTYLTLDRIG 402
BLAST of slc22a-11 vs. Ensembl Zebrafish
Match: si:dkey-119m7.4 (si:dkey-119m7.4 [Source:ZFIN;Acc:ZDB-GENE-040724-70]) HSP 1 Score: 85.5001 bits (210), Expect = 3.181e-17 Identity = 88/323 (27.24%), Postives = 148/323 (45.82%), Query Frame = 2
Query: 668 TPKYQCLSPNQTTDSITPDNCFYVPV--NSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISG--------VFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSII-GLVLVTELTPKKYRNF--IIINYWSVFS-IGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQ----ILNQNSEDEDFN-NKSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFYF-------VYQGTATNLEFAISDIYINAMIMGLIEIPA 1558
P C +P+Q D P +P+ +SS AK W+F K ST TE LVC + NI V A+ G L+D GR+ + LI I + P+ Y +++ LRF+ + + I+ VL TE T K R +I +Y+ F I +A + I+ W++ L + P FL+ +L +S +WL++N++ +EA ++++ I + ED+D +S +E + E +++ L+R + SL ++ VY G + N+ +IY+ MI GL+E+PA
Sbjct: 70 APGESC-TPSQ--DGSLPQRNHSLPITEHSSTAKGCTGGWEFSKEVFLSTIATEWDLVCEN-------ATMNNIGSSIYMFGLLVGAVLFGALADKYGRRIIILIGLAIQAIFGVGAAFAPNFY-IYVLLRFVVGTTVSAVIMNAFVLGTEWTGPKKRMLAGVITDYFFGFGYILLAGVAYLIRD---WRKLQLAISAPSFLFLFYVWVLPKSARWLMANNKHEEALDLIRKAALINGKPLEDDDMELYQSPKSSEKLQEQRKYTVLD--LVRTPRMRKQSLILFYLWFVNVLVYYGLSLNISDFGMNIYLTQMIFGLVEMPA 376
BLAST of slc22a-11 vs. Ensembl Xenopus
Match: bub1b (BUB1B, mitotic checkpoint serine/threonine kinase [Source:Xenbase;Acc:XB-GENE-1010857]) HSP 1 Score: 105.916 bits (263), Expect = 3.124e-23 Identity = 137/566 (24.20%), Postives = 229/566 (40.46%), Query Frame = 2
Query: 500 MFTFSEIFFIRYKHLTNFRMAMEEIINLRLFLIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLS------------------PNQTTDSITPDNCFYVPV----------NSSL---AKFPCTKWK--FDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLF-GIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSED--EDFNNKSIDDTETVHENK----RFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTS---VVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLI---ISMILFGLI----------IPSINKTSLPNTVEEAEQIKKD 2023
M TF E+ +H+ F ++I L F +SV S + + +FL + P Y+C+S PN +TDS+ C+ V NSSL +K P T K +D + S+ VTE LVC + NI G F + G ++D GRKP FLI S T I+ +L +Y L + RFI+ F G + G +LV E ++R + I Y + F++G+ + +W+ + P F + + ESP+WLIS +RK EA ++ + + + DF D E + + + IL+ + VYQG+ ++ +IY + I L+E P+ L ++ +G I T I + + IP + ++ L+C+S+ + V++ ++ + L+PT F+ N G D GG +Y + I + +I+F ++ +P +LP T+EEAE + K
Sbjct: 1 MATFDELL----EHIGEFDAFQKQIFILLCF-------ISVVFSPIYVGI-VFLGFVPDYRCVSAGIPEPSNECEWTLNYTGPNGSTDSLYMSQCYQYDVDWNSTSLNCTNSSLNITSKLPITNCKDGWDYNTTGSSLVTEFNLVCGDSWKLDFFQSCVNI-GFFIGGLISGYIADRFGRKP-FLISSILITGIFGILMAFAPNYPLVVTFRFIQGFVSKGCWLSGYILVAEFVGLEHRRTVGIVYQAAFTVGLLLLSGVAYVLPHWRWLQMTVTIPYFFFLAYYWCVPESPRWLISQNRKAEAKAIIHTIAKKNGKMVPDFLESLTADEEAGEKQVPSFLDLVRTPQIRKHTLILMYIWFTCAVVYQGSIMHMGSTAENIYFDFFISALVEFPSAILIIVTVDRVGRRYPWLVCCIITGITCLITAFIPHGYSWLI----------ITLSCVSRMGITVSYEMVCLVNAELYPT----FIRNLG------------IMVCSSMCDLGGVITPFIVYRLAAIWQELPLIVFAVLATVSGILVYFLPETKGRALPETIEEAENLHKQ 526
BLAST of slc22a-11 vs. Ensembl Xenopus
Match: rexo5 (RNA exonuclease 5 [Source:Xenbase;Acc:XB-GENE-980884]) HSP 1 Score: 89.3521 bits (220), Expect = 5.784e-18 Identity = 117/484 (24.17%), Postives = 205/484 (42.36%), Query Frame = 2
Query: 662 YYTPKYQCLSPN--QTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLV-----LVTELTPKKYRNFIIINYWSVFSIG--MAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQ-NSEDEDFNNKSIDDTET-----VHENKRFCHSKSLLIRLGILL-------ITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGS---VTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQF 2032
Y TP+Y L N Q D + + C W +D S+ ST +T+ LVCN R ++ + + ++GV ++ G LSD GR+P+ + + ++ I P++ IF RF+ G+++ G+V L+ E P R F +++G + + ++ R +W Q L A+ P F Y L + ES +WL+ + + + A + L+ + + N + E +++ ++ + +K +S L+R ++ T S F Y G A +L+ IYI +I G ++IPA Y IG +I I ++ +P ++ QT + S +A K L ++N L ++ L+PT R + G T + D S I+G L I+S I G +P LP T+E+ E+ +K S +
Sbjct: 83 YTTPQYHLLMDNFTQNVDELETETCV-------------DGWVYDHSEFASTIITQWDLVCNHRRMRQVAQSIY-MAGVLVGSVVFGGLSDKFGRRPLNIWSNLQMSVTGICAAFSPNYIWYCIF-RFLT----GTALSGIVLNSYSLIVEWIPTGNRAFTSTATGYCYTMGQLVLVGLAFMIRDWHWLQ--LAASLPFFFYFLYSWWIPESGRWLVLSGKPEVACKALKKVAKINGKKEAGEKLTVEVLKSSMQREISASKHSTYSVLDLVRTPVVRRISFCISCTWFSTSFAYYGLALDLQSFGVSIYIIQIIFGTVDIPAKFFSYFVMTYIGRRVLQALTLILAGIAILVNICVPQDY-------QTVRTS---MAVFGKGCLAASFNCLFLYTGELYPTVIRQ--SGMGLGTMMARLGGIIAPLAQMTGDI-YHSLPLIIFGCLPILSGIA-GCFLPETLGVPLPETIEDVERSEKHSLY 531
BLAST of slc22a-11 vs. Ensembl Xenopus
Match: rexo5 (RNA exonuclease 5 [Source:Xenbase;Acc:XB-GENE-980884]) HSP 1 Score: 87.8113 bits (216), Expect = 1.729e-17 Identity = 116/481 (24.12%), Postives = 203/481 (42.20%), Query Frame = 2
Query: 662 YYTPKYQCLSPN--QTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLV-----LVTELTPKKYRNFIIINYWSVFSIG--MAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQ-NSEDEDFNNKSIDDTET-----VHENKRFCHSKSLLIRLGILL-------ITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGS---VTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKD 2023
Y TP+Y L N Q D + + C W +D S+ ST +T+ LVCN R ++ + + ++GV ++ G LSD GR+P+ + + ++ I P++ IF RF+ G+++ G+V L+ E P R F +++G + + ++ R +W Q L A+ P F Y L + ES +WL+ + + + A + L+ + + N + E +++ ++ + +K +S L+R ++ T S F Y G A +L+ IYI +I G ++IPA Y IG +I I ++ +P ++ QT + S +A K L ++N L ++ L+PT R + G T + D S I+G L I+S I G +P LP T+E+ E+ K+
Sbjct: 83 YTTPQYHLLMDNFTQNVDELETETCV-------------DGWVYDHSEFASTIITQWDLVCNHRRMRQVAQSI-YMAGVLVGSVVFGGLSDKFGRRPLNIWSNLQMSVTGICAAFSPNYIWYCIF-RFLT----GTALSGIVLNSYSLIVEWIPTGNRAFTSTATGYCYTMGQLVLVGLAFMIRDWHWLQ--LAASLPFFFYFLYSWWIPESGRWLVLSGKPEVACKALKKVAKINGKKEAGEKLTVEVLKSSMQREISASKHSTYSVLDLVRTPVVRRISFCISCTWFSTSFAYYGLALDLQSFGVSIYIIQIIFGTVDIPAKFFSYFVMTYIGRRVLQALTLILAGIAILVNICVPQDY-------QTVRTS---MAVFGKGCLAASFNCLFLYTGELYPTVIRQ--SGMGLGTMMARLGGIIAPLAQMTGDI-YHSLPLIIFGCLPILSGIA-GCFLPETLGVPLPETIEDVERDSKE 528
BLAST of slc22a-11 vs. Ensembl Xenopus
Match: rexo5 (RNA exonuclease 5 [Source:Xenbase;Acc:XB-GENE-980884]) HSP 1 Score: 87.8113 bits (216), Expect = 1.834e-17 Identity = 120/500 (24.00%), Postives = 208/500 (41.60%), Query Frame = 2
Query: 662 YYTPKYQCLSPN--QTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLV-----LVTELTPKKYRNFIIINYWSVFSIG--MAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQ-NSEDEDFNNKSIDDTET-----VHENKRFCHSKSLLIRLGILL-------ITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGS---VTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAE--QIKKDSQFCFTESIGDKIVEEY 2074
Y TP+Y L N Q D + + C W +D S+ ST +T+ LVCN R ++ + + ++GV ++ G LSD GR+P+ + + ++ I P++ IF RF+ G+++ G+V L+ E P R F +++G + + ++ R +W Q L A+ P F Y L + ES +WL+ + + + A + L+ + + N + E +++ ++ + +K +S L+R ++ T S F Y G A +L+ IYI +I G ++IPA Y IG +I I ++ +P ++ QT + S +A K L ++N L ++ L+PT R + G T + D S I+G L I+S I G +P LP T+E+ E Q K S C E ++ +
Sbjct: 83 YTTPQYHLLMDNFTQNVDELETETCV-------------DGWVYDHSEFASTIITQWDLVCNHRRMRQVAQSIY-MAGVLVGSVVFGGLSDKFGRRPLNIWSNLQMSVTGICAAFSPNYIWYCIF-RFLT----GTALSGIVLNSYSLIVEWIPTGNRAFTSTATGYCYTMGQLVLVGLAFMIRDWHWLQ--LAASLPFFFYFLYSWWIPESGRWLVLSGKPEVACKALKKVAKINGKKEAGEKLTVEVLKSSMQREISASKHSTYSVLDLVRTPVVRRISFCISCTWFSTSFAYYGLALDLQSFGVSIYIIQIIFGTVDIPAKFFSYFVMTYIGRRVLQALTLILAGIAILVNICVPQDY-------QTVRTS---MAVFGKGCLAASFNCLFLYTGELYPTVIRQ--SGMGLGTMMARLGGIIAPLAQMTGDI-YHSLPLIIFGCLPILSGIA-GCFLPETLGVPLPETIEDVESPQTTKLSSQCQMEGHQKRLSSHF 547
BLAST of slc22a-11 vs. Ensembl Xenopus
Match: rexo5 (RNA exonuclease 5 [Source:Xenbase;Acc:XB-GENE-980884]) HSP 1 Score: 86.6557 bits (213), Expect = 3.796e-17 Identity = 116/483 (24.02%), Postives = 202/483 (41.82%), Query Frame = 2
Query: 662 YYTPKYQCLSPN--QTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLV-----LVTELTPKKYRNFIIINYWSVFSIG--MAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQ-NSEDEDFNNKSIDDTET-----VHENKRFCHSKSLLIRLGILL-------ITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGS---VTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQ 2029
Y TP+Y L N Q D + + C W +D S+ ST +T+ LVCN R ++ + + ++GV ++ G LSD GR+P+ + + ++ I P++ IF RF+ G+++ G+V L+ E P R F +++G + + ++ R +W Q L A+ P F Y L + ES +WL+ + + + A + L+ + + N + E +++ ++ + +K +S L+R ++ T S F Y G A +L+ IYI +I G ++IPA Y IG +I I ++ +P ++ QT + S +A K L ++N L ++ L+PT R + G T + D S I+G L I+S I G +P LP T+E+ E K +
Sbjct: 83 YTTPQYHLLMDNFTQNVDELETETCV-------------DGWVYDHSEFASTIITQWDLVCNHRRMRQVAQSIY-MAGVLVGSVVFGGLSDKFGRRPLNIWSNLQMSVTGICAAFSPNYIWYCIF-RFLT----GTALSGIVLNSYSLIVEWIPTGNRAFTSTATGYCYTMGQLVLVGLAFMIRDWHWLQ--LAASLPFFFYFLYSWWIPESGRWLVLSGKPEVACKALKKVAKINGKKEAGEKLTVEVLKSSMQREISASKHSTYSVLDLVRTPVVRRISFCISCTWFSTSFAYYGLALDLQSFGVSIYIIQIIFGTVDIPAKFFSYFVMTYIGRRVLQALTLILAGIAILVNICVPQDY-------QTVRTS---MAVFGKGCLAASFNCLFLYTGELYPTVIRQ--SGMGLGTMMARLGGIIAPLAQMTGDI-YHSLPLIIFGCLPILSGIA-GCFLPETLGVPLPETIEDVESSDKKQK 530
BLAST of slc22a-11 vs. Ensembl Mouse
Match: Slc22a1 (solute carrier family 22 (organic cation transporter), member 1 [Source:MGI Symbol;Acc:MGI:108111]) HSP 1 Score: 96.2857 bits (238), Expect = 2.760e-20 Identity = 109/485 (22.47%), Postives = 195/485 (40.21%), Query Frame = 2
Query: 656 FLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTK-WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSED---EDFNNKSIDDTETVHENKRFC---HSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAG--------PLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLI---ISMILFG----------LIIPSINKTSLPNTVEEAEQIKK 2020
FL KY+ T D + P + S L PC W +D S+ VTE LVC + + N+ G F ++ +G ++D GRK L+ + ++ +L + P + S+ +F + GS + G L+TE YR I Y F++G+ W+ L + P FL+ L + ESP+WL+S R +A +++ + Q + D +++ + + F + SL IL+ S +YQG ++ +++Y++ L+E PA +G + IA ++ + + I + + +W LN+T LACL + + ++ + L+PT F+ N G D GG ++ ++ + + +ILFG L++P +LP T+EEAE + +
Sbjct: 85 FLSQCMKYEVDWNQSTLDCVDPLSSLAAN-RSHLPLSPCEHGWVYDTPG--SSIVTEFNLVCGDAWKVDLFQSCVNL-GFFLGSLVVGYIADRFGRKLCLLVTTLVTSLSGVLTAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAILYQVAFTVGLVGLAGVAYAIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTQAVRIMEQIAQKNRKVPPADLKMMCLEEDASERRSPSFADLFRTPSLRKHTLILMYLWFSCAVLYQGLIMHVGATGANLYLDFFYSSLVEFPAAFIILVTIDRIGRIYPIAASNLVAGAACLLMIFIPHEL---HW---LNVT---------LACLGRMGATIVLQMVCLVNAELYPT----FIRNLGMMVCSALC------------DLGGIFTPFMVFRLMEVWQALPLILFGVLGLSAGAVTLLLPETKGVALPETIEEAENLGR 534
BLAST of slc22a-11 vs. Ensembl Mouse
Match: Slc22a3 (solute carrier family 22 (organic cation transporter), member 3 [Source:MGI Symbol;Acc:MGI:1333817]) HSP 1 Score: 92.4337 bits (228), Expect = 5.198e-19 Identity = 113/474 (23.84%), Postives = 208/474 (43.88%), Query Frame = 2
Query: 686 LSPNQTTDSITPDNCFYVPVNSSLAKFPCT-KWKFDKSKIKSTFVTELKLVCNQRF---LQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIK-LFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSW----LIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQIL---NQNSEDEDFNNKSIDDTETVHENK-RFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGS----VTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIY----GILLIISMILFG----------LIIPSINKTSLPNTVEEAEQI 2014
L T+ ++ D P N S C+ W++ ++ ST V++ LVC+ + L ++ L ++G F LG +D GR ++LI I +++ P ++S+ + RF++ +FG G+ + V+VTE+ K R + I F++G+ + P AY+ SW L + P FL+ L ++ ESP+WLI+ + ++A ++L+ + N +++ ++ D E + + + + IL+ + VYQG L ++YI+ I GL+E+P L L+ +G S ++ L++ + G P L T +A L + + +A+ I+ + L+PT RNF + D GG A F+ I L + +I+FG +++P +LP TVE+ E++
Sbjct: 95 LEATNTSSELSCDPLTAFP-NRSAPLVSCSGDWRYVETH--STIVSQFDLVCSNAWMLDLTQAILNLGFLAGAFT--LGYAADRYGRLIIYLISCFGVGITGVVVAFAP-NFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVGIVIQMFFTLGIIILP----GIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNGKHLSSNYSEITVTDEEVSNPSCLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGLIGGNLYIDFFISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTAFLPEG--IPWLRTT---------VATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLC----------------DFGGI-IAPFLLFRLAAIWLELPLIIFGILASVCGGLVMLLPETKGIALPETVEDVEKL 530
BLAST of slc22a-11 vs. Ensembl Mouse
Match: Slc22a2 (solute carrier family 22 (organic cation transporter), member 2 [Source:MGI Symbol;Acc:MGI:1335072]) HSP 1 Score: 90.1225 bits (222), Expect = 2.764e-18 Identity = 114/486 (23.46%), Postives = 207/486 (42.59%), Query Frame = 2
Query: 656 FLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTK-WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIK-LFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQ-ILNQNSEDEDFNNKSI--DDTETVHENKRF---CHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIG-----SVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIY---GILLIISMILF----------GLIIPSINKTSLPNTVEEAEQIKKDSQ 2029
FL +Y+ T D + P + S L PC W +D S+ VTE LVC ++ + L N+ G F A+ +G L+D GRK L+ + I +L+ I P +Y+ + RF++ L +IG +L+TE YR + I Y F++G+ + W+ P F + L + ESP+WLIS ++ +A ++++ I +N + + +S+ D+ + N F + + IL+ + +YQG ++ A +IY++ L+E PA + L+ IG +V+++V ++ IP + Q KI+ +ACL + + +A+ ++ + L+PT RN + D GG +Y I L +++F L++P +LP T+E+AE++++ +
Sbjct: 85 FLSQCMRYEVDWNQSTLDCVDPLSSL-AANRSHLPLSPCEHGWVYDTPG--SSIVTEFNLVCAHSWMLDLFQSLVNV-GFFIGAVGIGYLADRFGRKFCLLVTILINAISGVLMAISP-NYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRTVGICYQIAFTVGLLILAGVAYALPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKNAKAMKIIKHIAKKNGKSVPVSLQSLTADEDTGMKLNPSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRIGRRYPWAVSNMV--AGAACLASVFIPDD-------LQWLKIT---VACLGRMGITIAYEMVCLVNAELYPTYIRNLAVLVCSSMC----------------DIGGIVTPFLVYRLTDIWLEFPLVVFAVVGLVAGGLVLLLPETKGKALPETIEDAEKMQRPRK 537
BLAST of slc22a-11 vs. Ensembl Mouse
Match: Slc22a2 (solute carrier family 22 (organic cation transporter), member 2 [Source:MGI Symbol;Acc:MGI:1335072]) HSP 1 Score: 88.9669 bits (219), Expect = 5.705e-18 Identity = 114/482 (23.65%), Postives = 205/482 (42.53%), Query Frame = 2
Query: 656 FLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTK-WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIK-LFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQ-ILNQNSEDEDFNNKSI--DDTETVHENKRF---CHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIG-----SVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIY---GILLIISMILF----------GLIIPSINKTSLPNTVEEAEQIK 2017
FL +Y+ T D + P + S L PC W +D S+ VTE LVC ++ + L N+ G F A+ +G L+D GRK L+ + I +L+ I P +Y+ + RF++ L +IG +L+TE YR + I Y F++G+ + W+ P F + L + ESP+WLIS ++ +A ++++ I +N + + +S+ D+ + N F + + IL+ + +YQG ++ A +IY++ L+E PA + L+ IG +V+++V ++ IP + Q KI+ +ACL + + +A+ ++ + L+PT RN + D GG +Y I L +++F L++P +LP T+E+AE+++
Sbjct: 85 FLSQCMRYEVDWNQSTLDCVDPLSSL-AANRSHLPLSPCEHGWVYDTPG--SSIVTEFNLVCAHSWMLDLFQSLVNV-GFFIGAVGIGYLADRFGRKFCLLVTILINAISGVLMAISP-NYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRTVGICYQIAFTVGLLILAGVAYALPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKNAKAMKIIKHIAKKNGKSVPVSLQSLTADEDTGMKLNPSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRIGRRYPWAVSNMV--AGAACLASVFIPDD-------LQWLKIT---VACLGRMGITIAYEMVCLVNAELYPTYIRNLAVLVCSSMC----------------DIGGIVTPFLVYRLTDIWLEFPLVVFAVVGLVAGGLVLLLPETKGKALPETIEDAEKMQ 533
BLAST of slc22a-11 vs. Ensembl Mouse
Match: Slc22a4 (solute carrier family 22 (organic cation transporter), member 4 [Source:MGI Symbol;Acc:MGI:1353479]) HSP 1 Score: 79.7221 bits (195), Expect = 5.501e-15 Identity = 114/465 (24.52%), Postives = 187/465 (40.22%), Query Frame = 2
Query: 593 LIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPN---------------QTTDSI-TPDNCFYVPVNS------------------SLAKFPC-TKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFL-GILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFG-IGSSIIGLVLVTELTPKKYRN-FIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAA--------FPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDTETVHENKRFCHSKSLLIRL----GILLITSLSF---------YFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGS---VTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRN 1801
LI+F++S S+ +G + +FL TP+++CL P+ +T D P +C + + L + C W++DK ST VTE LVC + + L + + F+ G LSD GRK + T + + I +++ + L I G I + ++ +L TE+ K R F + + F+IG + P FAY+ + W + F + L+ P ESP+WLIS R EA +++Q + I D + E K +++ L I IT ++ YF NL D+Y+N + GLIE+PA +L + + V+ W L+ ++P ++ N G L L KF + A+++L VF L+PT RN
Sbjct: 20 LIFFLLSASIIPNGFNGMSVVFLAGTPEHRCLVPDTVNLSSSWRNHSIPLETKDGRQVPQSCRRYRLATIANFSAMGLEPGQDVDLEQLEQESCLDGWEYDKDIFLSTIVTEWNLVCEDDWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKVLFATMAVQTG-FSFVQIFSTNWEMFTVLFAIVGMGQISNYVVAFILGTEILSKSVRIIFSTLGVCTFFAIGYMVLP----LFAYFIRDWRMLLLALTLPGLFCVPLWWFIP----ESPRWLISQRRFAEAEQIIQ--KAAKMNSIVAPAGIFDPLELQELNSLKQQKVIILDLFRTRNIATITVMAVMLWMLTSVGYFALSLNVPNLH---GDVYLNCFLSGLIEVPAYFTAWLLLRTLPRRYIIAGVLFWGGGVLLLIQVVPEDY----NFVSIG------LVMLGKFGITSAFSMLYVFTAELYPTLVRN 460
BLAST of slc22a-11 vs. UniProt/SwissProt
Match: sp|Q8MJI6|S22A2_RABIT (Solute carrier family 22 member 2 OS=Oryctolagus cuniculus OX=9986 GN=SLC22A2 PE=1 SV=1) HSP 1 Score: 103.605 bits (257), Expect = 9.231e-22 Identity = 112/473 (23.68%), Postives = 194/473 (41.01%), Query Frame = 2
Query: 695 NQTTDSITPDNCFYVPVNSSLAKFPCTK-WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQ-ILNQNSEDEDFNNKSIDDTETVHE--NKRF---CHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYS------IIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIY---GILLIISMILFG----------LIIPSINKTSLPNTVEEAEQIKKDSQ 2029
NQ++ P S L PC W +D S+ VTE LVC + ++ + NI G F ++ +G L+D GRK L+ + +L+ + P++ + IF L +IG +L+TE YR + I Y F++G+ + W+ L P F + L + ESP+WLIS ++ +A +++ I +N + + +S+ E V E N F + + IL+ + +YQG +L A DIY++ L+E PA +L I V W +++ + +P D + L T +ACL + + +A+ ++ + L+PT F+ N G D GG +Y I L + +++F L++P +LP T+EEAE +++ +
Sbjct: 96 NQSSPGCVDPLASLAPNRSHLPLGPCQHGWVYDTPG--SSIVTEFNLVCARSWMLDLFQSAVNI-GFFIGSVGIGYLADRFGRKLCLLVTILINAAAGVLMAVSPNYTWMLIFRLIQGLVSKAGWLIGYILITEFVGLNYRRTVGILYQVAFTVGLLVLAGVAYALPRWRWLQLTVTLPYFCFLLYYWCIPESPRWLISQNKNAKAMRIMEHIAKKNGKSLPVSLQSLRAAEDVGEKLNPSFLDLVRTPQIRKHTCILMYNWFTSSVLYQGLIMHLGLAGGDIYLDFFYSALVEFPA---AFLIIATIDRVGRRYPWAVSNMVAGAACLASVFVP---DDLQGLRIT-------VACLGRMGITMAYEMVCLVNAELYPT----FIRNLGVLVCSSLC------------DVGGIVTPFLVYRLTAIWLQLPLVVFAVVGLVAGGLVLMLPETKGRTLPETIEEAENLQRPRK 536
BLAST of slc22a-11 vs. UniProt/SwissProt
Match: sp|O08966|S22A1_MOUSE (Solute carrier family 22 member 1 OS=Mus musculus OX=10090 GN=Slc22a1 PE=1 SV=2) HSP 1 Score: 96.2857 bits (238), Expect = 1.931e-19 Identity = 109/485 (22.47%), Postives = 195/485 (40.21%), Query Frame = 2
Query: 656 FLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTK-WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSED---EDFNNKSIDDTETVHENKRFC---HSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAG--------PLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLI---ISMILFG----------LIIPSINKTSLPNTVEEAEQIKK 2020
FL KY+ T D + P + S L PC W +D S+ VTE LVC + + N+ G F ++ +G ++D GRK L+ + ++ +L + P + S+ +F + GS + G L+TE YR I Y F++G+ W+ L + P FL+ L + ESP+WL+S R +A +++ + Q + D +++ + + F + SL IL+ S +YQG ++ +++Y++ L+E PA +G + IA ++ + + I + + +W LN+T LACL + + ++ + L+PT F+ N G D GG ++ ++ + + +ILFG L++P +LP T+EEAE + +
Sbjct: 85 FLSQCMKYEVDWNQSTLDCVDPLSSLAAN-RSHLPLSPCEHGWVYDTPG--SSIVTEFNLVCGDAWKVDLFQSCVNL-GFFLGSLVVGYIADRFGRKLCLLVTTLVTSLSGVLTAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAILYQVAFTVGLVGLAGVAYAIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTQAVRIMEQIAQKNRKVPPADLKMMCLEEDASERRSPSFADLFRTPSLRKHTLILMYLWFSCAVLYQGLIMHVGATGANLYLDFFYSSLVEFPAAFIILVTIDRIGRIYPIAASNLVAGAACLLMIFIPHEL---HW---LNVT---------LACLGRMGATIVLQMVCLVNAELYPT----FIRNLGMMVCSALC------------DLGGIFTPFMVFRLMEVWQALPLILFGVLGLSAGAVTLLLPETKGVALPETIEEAENLGR 534
BLAST of slc22a-11 vs. UniProt/SwissProt
Match: sp|Q63089|S22A1_RAT (Solute carrier family 22 member 1 OS=Rattus norvegicus OX=10116 GN=Slc22a1 PE=1 SV=1) HSP 1 Score: 95.1301 bits (235), Expect = 5.098e-19 Identity = 111/482 (23.03%), Postives = 196/482 (40.66%), Query Frame = 2
Query: 656 FLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTK-WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVL-QILNQNSE--DEDFNNKSIDDTETVHENKRFC---HSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVV---IWTTIGLISYSIIPG--NWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLI---ISMILFG----------LIIPSINKTSLPNTVEEAEQIKK 2020
FL +Y+ T D + P + V S L PC W +D S+ VTE LVC + + N+ G F ++ +G ++D GRK L+ + ++ +L + P + S+ +F + GS + G L+TE YR I Y F++G+ W+ L + P FL+ L + ESP+WL+S R A ++ QI +N + D +++ + + F + +L IL+ S +YQG ++ +++Y++ L+E PA + ++ IG + + + T + IP +W LN+T LACL + + ++ + L+PT F+ N G D GG ++ ++ + + +ILFG L++P +LP T+EEAE + +
Sbjct: 85 FLSQCMRYEVDWNQSTLDCVDPLSSL-VANRSQLPLGPCEHGWVYDTPG--SSIVTEFNLVCGDAWKVDLFQSCVNL-GFFLGSLVVGYIADRFGRKLCLLVTTLVTSVSGVLTAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAILYQMAFTVGLVGLAGVAYAIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTRAVRIMEQIAQKNGKVPPADLKMLCLEEDASEKRSPSFADLFRTPNLRKHTVILMYLWFSCAVLYQGLIMHVGATGANLYLDFFYSSLVEFPAAFIILVTIDRIGRIYPIAASNLVTGAACLLMIFIPHELHW---LNVT---------LACLGRMGATIVLQMVCLVNAELYPT----FIRNLGMMVCSALC------------DLGGIFTPFMVFRLMEVWQALPLILFGVLGLTAGAMTLLLPETKGVALPETIEEAENLGR 534
BLAST of slc22a-11 vs. UniProt/SwissProt
Match: sp|O88446|S22A3_RAT (Solute carrier family 22 member 3 OS=Rattus norvegicus OX=10116 GN=Slc22a3 PE=2 SV=1) HSP 1 Score: 94.3597 bits (233), Expect = 8.265e-19 Identity = 113/474 (23.84%), Postives = 208/474 (43.88%), Query Frame = 2
Query: 686 LSPNQTTDSITPDNCFYVPVNSSLAKFPCT-KWKFDKSKIKSTFVTELKLVCNQRF---LQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIK-LFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSW----LIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQIL---NQNSEDEDFNNKSIDDTETVHENK-RFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGS----VTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIY----GILLIISMILFG----------LIIPSINKTSLPNTVEEAEQI 2014
L T+ ++ D P N S PC+ W++ ++ ST V++ LVC + L ++ L ++G F LG +D GR ++LI I +++ P ++S+ + RF++ +FG G+ + V+VTE+ K R + I F++G+ + P AY+ SW L + P FL+ L ++ ESP+WLI+ + ++A ++L+ + N +++ ++ D E + + + + IL+ + VYQG L ++Y++ I GL+E+P L L+ +G S ++ L++ + G P L T +A L + + +A+ I+ + L+PT RNF + D GG A F+ I L + +I+FG +++P +LP TVE+ E++
Sbjct: 95 LEDTNTSSELSCDPLAAFP-NRSAPLVPCSGDWRYVETH--STIVSQFDLVCGNAWMLDLTQAILNLGFLAGAFT--LGYAADRYGRLIVYLISCFGVGITGVVVAFAP-NFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVGIVIQMFFTLGIIILP----GIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNGKHLSSNYSEITVTDEEVSNPSCLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGLIGGNLYMDFFISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTAFLPEG--IPWLRTT---------VATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLC----------------DFGGI-IAPFLLFRLAAIWLELPLIIFGILASVCGGLVMLLPETKGIALPETVEDVEKL 530
BLAST of slc22a-11 vs. UniProt/SwissProt
Match: sp|A7MBE0|S22A1_BOVIN (Solute carrier family 22 member 1 OS=Bos taurus OX=9913 GN=SLC22A1 PE=2 SV=1) HSP 1 Score: 93.9745 bits (232), Expect = 9.705e-19 Identity = 112/481 (23.28%), Postives = 198/481 (41.16%), Query Frame = 2
Query: 671 PKYQCLSP----NQTTDSITPDNCFYVPVNSSLAKFPCTK-WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLGI--LSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSED---EDFNNKSIDDTETVHENKRFC---HSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWT-TIGLISYSIIPGNWD-PMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIIS---MILFG----------LIIPSINKTSLPNTVEEAEQIKKDSQ 2029
P+ QCL NQ+T S L PC + W +D S+ VTE LVC+ + + N+ G F LG+ ++D GRK L + + + +L + P + SL IF L GS G L+TE YR + I Y F++G+ + +W+ L + P+FL + ESP+WL+S R EA +++ + Q + D S+++ T + F + +L IL+ + VYQG ++ ++Y++ + L+E PAG + ++ G + GL + +I D P LN+ ++AC+ + + + + ++ + LFPT F+ N G D GG ++ ++ + +ILF L++P +LP T+E+AE +++ ++
Sbjct: 79 PESQCLRYEVDWNQSTLGCLDPLASLATNGSPLPLGPCEQGWVYDTPG--SSIVTEFNLVCDDSWKVDLFQSCVNL-GFFLGSLGVGYIADRFGRKVCLLATTLTCASLGVLTAVAPDYTSLLIFRLLQGLVSKGSWTAGYTLITEFVGLGYRRTVAILYQMAFTVGLVLLSGLAYILPHWRWLQLAVSLPIFLLLFRFWFVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFIDLFRTPNLRKYTFILMYLWFTSSVVYQGLIMHVGATGGNLYLDFLYSALVEFPAGFIILVTIDRFGRRYPLATSNLAAGLACFLMIFIPHDLPWLNI---------MVACVGRMGITIVFQMVCLVNAELFPT----FIRNLGMMVCSSLC------------DLGGVLTPFLVFRLMEVWQGSPLILFAALGLVAGGMTLLLPETKGVTLPETIEDAENLQRKAK 531
BLAST of slc22a-11 vs. TrEMBL
Match: A0A0H3YJA2 (Slc22a-11 OS=Schmidtea mediterranea OX=79327 GN=slc22a-11 PE=2 SV=1) HSP 1 Score: 987.638 bits (2552), Expect = 0.000e+0 Identity = 506/507 (99.80%), Postives = 506/507 (99.80%), Query Frame = 2
Query: 557 MAMEEIINLRLFLIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQFCFTESIGDKIVEEYK 2077
MAMEEIINLRLFLIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDD ETVHENKRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATGFIGAAIGGFAGYYYSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQFCFTESIGDKIVEEYK
Sbjct: 1 MAMEEIINLRLFLIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDIETVHENKRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATGFIGAAIGGFAGYYYSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQFCFTESIGDKIVEEYK 507
BLAST of slc22a-11 vs. TrEMBL
Match: A0A0H3YF32 (Slc22a-2 OS=Schmidtea mediterranea OX=79327 GN=slc22a-2 PE=2 SV=1) HSP 1 Score: 154.451 bits (389), Expect = 2.963e-36 Identity = 118/428 (27.57%), Postives = 205/428 (47.90%), Query Frame = 2
Query: 590 FLIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPN------QTTDSITPDNCFY-VPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYS-LHIFLRFIKLFGIGSSI---IGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSE----DEDFNN-KSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIP--------GNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRN 1801
++ + +S++ F+ V+FQ F Y PK+ CL N +T+ I+ D C Y + VN S K C +W F+K +++T + EL LVC++ F + ++ + +F+ ILSD G++ + ++ TII I G + S+ + L F+ G+ S+ + + E+ P + + N+W+++S G + F W+Q ++++ Y L + E+P+WL+ N R++EAF+ + + + ++ E+FN K I N K+++ R IL +F F Y G+AT+L FA +I+I +MGL+E+P GPL + + +G SV + +G+I I+P W P L + LA +K AW I + L PT RN
Sbjct: 18 YISFMTLSITTFKYVVEFQGLTFALYEPKFSCLVKNISSTIRNSTNLISKDQCQYRLSVNDSWNK--CDQWTFEKRFMRNTLINELNLVCDRAFYRELIFTTFFVGCLFSFPFSILSDSIGKRLLLIVSIFLSTIITI--GQMVSYQIWQQLVLSFVS--GVCKSVYVSLAYTTLIEIIPVSHIDLAATNFWNLYSFGYMSVALFAYIFRSWRQIYILSLITSIFYVLYFWFVPETPRWLMLNKRRNEAFKTMSFIAKINKCTLNKEEFNKWKPIQQVTGKFWN--LLKHKTMIYRFLILNFAGWAFSFAYIGSATDLTFASENIFITTFVMGLVELPTGPLSGIMANKLGRKKSVSALSGLGIICLIIMPFIEADSLKSVWQPWLKVC---------LAMGAKLGFSSAWLIFDIITNELIPTTDRN 428
BLAST of slc22a-11 vs. TrEMBL
Match: A0A267FBR0 (MFS domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig009851g1 PE=4 SV=1) HSP 1 Score: 125.946 bits (315), Expect = 1.451e-26 Identity = 118/498 (23.69%), Postives = 224/498 (44.98%), Query Frame = 2
Query: 596 IYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSITPDNCFYVPV--------NSSLAKFPCTKWKFDKSK-IKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQ----NSEDEDFNNKSIDDTETVHENKRFCHSKSLLIRLGILLITSLS-FYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIG---LISYSIIPGNWDPMLNLTQTG---KISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQ 2029
I+ +S + F++ +D ++ + + K++C N ++D + + + + N +L CTK+ + I + V E LVC+++ ++ + + + G L D GRK + ++C +D I IL +P+ + IF RF+K F GL+++ E+T +K+R + YW + +G + + F W + L + Y + +++ ESP+WL+ R +EA +VL+ + + E + K++D E N + + I++ ++L+ F Y G +T+ F ++I +N ++ G +EIP+ +G+L S G + VI T + LI+ I+P TG I +++A + K L + I V+ +FPT+ RN AT + +D F I+GI I+S + L++P LP TV +E + + +
Sbjct: 20 IFLALSFTSFKAVLDLELMVLTLHESKFRCAQQN-SSDYVAQNYSEHCSISRLVGDDTNFTLINETCTKFDYQHGDVISKSMVEEYDLVCDRKHYATGMMSVFFLGCALGMLFGTLGDKIGRKKILIVCGVTDLITTILPAFMPTAET-QIFARFLKGFPAAVYYQGLLIMEEMTEEKHRAVLGNLYWLFWCVGYMFSGVVVYIFKEWDKIQLFSTVFCLNYIVIFIVVPESPRWLVLKGRVEEAVDVLKRIAKWNGIKWEHKVSKVKALDVEEEPTGNILDLVTYPEMRMKSIVIFSNLAMFAMCYFGLSTDTTFITTNIVLNVLLNGAVEIPSSFIGWLGSDRYGRKYTTVIITVLSGFCLIAVPIVP-----------TGGVYNIVKAVVAMVGKCLLTTGYCIADVWAAEIFPTSVRN--NGLFLATTLAMLSNIVAPVINTLSDVATF-LPGLIFGITSIVSALSL-LLLPETKGLPLPETVPSSEGLVRGRE 500
BLAST of slc22a-11 vs. TrEMBL
Match: A0A183ATJ5 (MFS domain-containing protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS10280 PE=4 SV=1) HSP 1 Score: 125.176 bits (313), Expect = 4.899e-26 Identity = 129/553 (23.33%), Postives = 227/553 (41.05%), Query Frame = 2
Query: 530 RYKHLTNFRMAMEEIINLRLFL------IYFIISVSVFQS------GVDFQMSMFLYYTPKYQCLSP----NQTT--------------------------DSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFL----YGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDTETVHENKRFCH---SKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISH----SILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQ 2029
R + T F+M+ E N L Y+I + VF S G++ Q +F++YTP++ C N TT DS P + + + C+ W + ++ T VT+ LVC +R L + +S + + D GRK +FL + I+ L+ H+ LR ++ G + IG+ +++EL P R YW +FS+G AY + W+ M + Y P IL ESP+WL R +EA +L+ ++ +++S +D +V F + ++L +RL I ++ Y G TN FA +I++N ++MGL E+P+G +L S G S+ + + ++S + LT+ G H +++A KF L VA+ ++ ++ +FPT+ R F + A+ F G IY + + +L ++P L T+ E+E++ + ++
Sbjct: 7 RSVNQTRFKMSETEPENFETILKHIYGKAYYIRVIFVFCSMTSLITGLEMQSLIFMHYTPEHNCTDRRIPLNDTTVYWFSERPNIDLSRVNGTQLEAASGFDSREPCWAVFAGSSDEFIQLACSNWTYATRPMQQTVVTQFNLVCERRIWVPWLESVFLLSVAIGFLMASIGDTIGRKKLFLGLALFQ-IVTSLITPFTHTVEFHLILRCLRGLCPGLAYIGINILSELVPIHRRAAYGNVYWLLFSVGYVTC----AGMAYLTRDWVQLRLWMCVFFTGYITFPFILCESPRWLCLQGRPEEATRILKRESEAMRRNLLSDQS-NDQRSVRRKDSFLNLFTYRNLRLRLFIFCFVHVAITTAYLGLITNNAFATDNIFLNVVLMGLSEMPSGIAAWLVSEYSGRRLSITLLLALTVVS-----------VGLTELGAFIHPVFRAVMAIGGKFFLSVAYCVIDLYVFEIFPTSTRTSSFFFVNTVASLFGALAPFINNLTRFSQFG---PTLIYCAITALGAVLVFALLPETRDCPLAQTLAESERLVRGNE 539
BLAST of slc22a-11 vs. TrEMBL
Match: A0A267GXD4 (MFS domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig033092g1 PE=4 SV=1) HSP 1 Score: 124.02 bits (310), Expect = 6.519e-26 Identity = 118/498 (23.69%), Postives = 223/498 (44.78%), Query Frame = 2
Query: 596 IYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSITPDNCFYVPV--------NSSLAKFPCTKWKFDKSK-IKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQ----NSEDEDFNNKSIDDTETVHENKRFCHSKSLLIRLGILLITSLS-FYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIG---LISYSIIPGNWDPMLNLTQTG---KISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQ 2029
I+ +S + F++ +D ++ + + K++C N ++D + + + + N +L CTK+ + I + V E LVC+++ ++ + + + G L D GRK + ++C +D I IL +P+ + IF RF+K F GL+++ E+T +K+R + YW + +G + + F W + L + Y + +++ ESP+WL+ R +EA +VL+ + + E + K++D E N + + I++ +L+ F Y G +T+ F ++I +N ++ G +EIP+ +G+L S G + VI T + LI+ I+P TG I +++A + K L + I V+ +FPT+ RN AT + +D F I+GI I+S + L++P LP TV +E + + +
Sbjct: 20 IFLALSFTSFKAVLDLELMVLTLHESKFRCAQQN-SSDYVAQNYSEHCRISRLVGDDTNFTLINETCTKFDYQHGDVISKSMVEEYNLVCDRKHYATGMMSVFFLGCALGMLFGTLGDKIGRKKILIVCGVTDLITTILPAYMPTAET-QIFARFLKGFPAAVYYQGLLIMEEMTEEKHRAVLGNLYWLFWCVGYMFSGVVVYIFKEWDKIQLFSTVFCLNYIVIFIVVPESPRWLVLKGRVEEAVDVLKRIAKWNGIKWEHKVSKVKALDVEEEPTGNILDLVTYPEMRMKSIVIFFNLAMFAMCYFGLSTDTTFITTNIVLNVLLNGAVEIPSSFIGWLGSDRYGRKYTTVIITVLSGFCLIAVPIVP-----------TGGVYNIVKAVVAMVGKCLLTTGYCIADVWAAEIFPTSVRN--NGLFLATTLAMLSNIVAPVINTLSDVATF-LPGLIFGITSIVSALSL-LLLPETKGLPLPETVPSSEGLVRGRE 500
BLAST of slc22a-11 vs. Ensembl Cavefish
Match: si:dkey-119m7.4 (solute carrier family 22 member 13-like [Source:NCBI gene;Acc:103028301]) HSP 1 Score: 91.6633 bits (226), Expect = 5.884e-19 Identity = 124/534 (23.22%), Postives = 215/534 (40.26%), Query Frame = 2
Query: 647 MSMFLYYTPKYQCLSP-------NQTTDSITPDNCFYVPVNSSLAKFPCTK----WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISG--------VFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGL-----VLVTELTPKKYRNF--IIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVL--------QILNQNSEDEDFNNKSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFYF-------VYQGTATNLEFAISDIYINAMIMGLIEIPAGP-----------LGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIIS----MILFGL----------IIPSINKTSLPNTVEEAEQIKKDSQFCFTESI 2050
+S+F P + C N T + C NSSL+ T W+F K ST VTE LVC+ L NI V A+ G+L+D GR+ + L+ + + P+ + +++ LRF+ +G+++ G+ VL TE T K+R II +Y+ F +G + W++ L + P F++ +L +S +WL++N +++EA +++ + L N + NN ++ + + H+ L+R + SL ++ VY G + N+ +IY+ +I GL+E+PA + LS +A+G + ++ TI IP N + +ILA L KF + + +I+ V+ +FPT R G G A IY +L IS M++FGL ++P LP+T+E+ E ++ ++ I
Sbjct: 37 VSVFTGAVPPHLCRDTKTHTHNFNFTLSQSASEACGSTHTNSSLSTHTTTACRDGWEFSKDVFLSTVVTEFDLVCDSA-------TLNNIGSSIYMFGLLVGAVVFGVLADRYGRRIIILVGLALQAMFGVGAAFAPNFF-IYVLLRFV----VGTTVSGIIMNAFVLGTEWTGPKHRMLAGIITDYF--FGVGYILLAGVAYLIRDWRKLQLAISAPGFIFIFYIWVLPKSARWLMANGKQEEAMDLICKAALINKKPLKGNDMEFQLNNCKVE------QKLQRKHTVVDLVRTPQMRKQSLILFYLWFVNVLVYYGLSLNVSDFGMNIYLTQLIFGLVEMPARTITLFTLNRSRRISQLSFLAVGGLACLL---TI------FIPQNL----------PVVRTILAMLGKFGITASLSIVYVYSAEVFPTVVRQNGIGMGSMCA-----------------RAGGVIAPIIY-LLRRISPHAPMVVFGLCPLVGALLTILLPETAHKPLPDTIEDVEGTSNKAETQISDGI 513
BLAST of slc22a-11 vs. Ensembl Cavefish
Match: oct2 (solute carrier family 22 member 3 [Source:NCBI gene;Acc:103033951]) HSP 1 Score: 88.9669 bits (219), Expect = 4.657e-18 Identity = 105/441 (23.81%), Postives = 187/441 (42.40%), Query Frame = 2
Query: 737 VPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQIL---NQNSEDEDFNNKSI---DDTETVHEN-KRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLI--IPSINKTSLPNTVEEAEQIKKDS 2026
+P N++ W FD + +T VTE LVC++ +L L +G F A G ++D GRK F+ + I L I P++ +F F G+ VLV E R F+ + +++S GM + P WK L P+F++ + + ESP+WL+S R EA V+Q + N+ S DF + E VH + K + + IL+ + V+QG L +++++ I ++E+P G + YL +G + + ++ I+P +TQ I+A + + ++ + + ++ L+PT RN + + IGA F Y ++ F+YG++ S++ GL+ +P + LP T+++ E K+
Sbjct: 108 IPTNTTPLTSCDEGWTFDLTW--TTVVTEFVLVCDRSWLA-DLNQATLAAGFFIGAFVSGYIADRFGRKLCFIGSMLGLGVSGICLIISPNYPLFLVFRCLQGFFAKGAWTTTYVLVIEFFGSNNRKFVSVMTRTLYSTGMVLIPGLAYYIHSWKYLQLTMTLPIFIFLVYYWAIPESPRWLLSQKRTKEAMIVIQNIAKCNKRSVPADFQEMDLLVEQQQEIVHPSFKDLFRTPKMRKHTIILIYAWFTSTVVFQGLLLRLGITGDNLFLDFFISAVVELPTGLIFYLLVDRVGRRPLIATANLVAGLACLIVP-------FVTQNISWLRRIIAIIGRLAVAIGFETVNFANSELYPTPLRNLGVSVCSSASDIGAVAAPFLLYRLASIWQELPL--FLYGVM---SLVYSGLVTMLPEMKGVDLPETIDDVENRGKED 533
BLAST of slc22a-11 vs. Ensembl Cavefish
Match: oct2 (solute carrier family 22 member 3 [Source:NCBI gene;Acc:103033951]) HSP 1 Score: 87.4261 bits (215), Expect = 1.499e-17 Identity = 104/436 (23.85%), Postives = 185/436 (42.43%), Query Frame = 2
Query: 737 VPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQIL---NQNSEDEDFNNKSI---DDTETVHEN-KRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLI--IPSINKTSLPNTVEEAEQ 2011
+P N++ W FD + +T VTE LVC++ +L L +G F A G ++D GRK F+ + I L I P++ +F F G+ VLV E R F+ + +++S GM + P WK L P+F++ + + ESP+WL+S R EA V+Q + N+ S DF + E VH + K + + IL+ + V+QG L +++++ I ++E+P G + YL +G + + ++ I+P +TQ I+A + + ++ + + ++ L+PT RN + + IGA F Y ++ F+YG++ S++ GL+ +P + LP T+++ E
Sbjct: 108 IPTNTTPLTSCDEGWTFDLTW--TTVVTEFVLVCDRSWLA-DLNQATLAAGFFIGAFVSGYIADRFGRKLCFIGSMLGLGVSGICLIISPNYPLFLVFRCLQGFFAKGAWTTTYVLVIEFFGSNNRKFVSVMTRTLYSTGMVLIPGLAYYIHSWKYLQLTMTLPIFIFLVYYWAIPESPRWLLSQKRTKEAMIVIQNIAKCNKRSVPADFQEMDLLVEQQQEIVHPSFKDLFRTPKMRKHTIILIYAWFTSTVVFQGLLLRLGITGDNLFLDFFISAVVELPTGLIFYLLVDRVGRRPLIATANLVAGLACLIVP-------FVTQNISWLRRIIAIIGRLAVAIGFETVNFANSELYPTPLRNLGVSVCSSASDIGAVAAPFLLYRLASIWQELPL--FLYGVM---SLVYSGLVTMLPEMKGVDLPETIDDVEN 528
BLAST of slc22a-11 vs. Ensembl Cavefish
Match: ENSAMXT00000002313.2 (solute carrier family 22 member 7-like [Source:NCBI gene;Acc:103025489]) HSP 1 Score: 86.6557 bits (213), Expect = 2.161e-17 Identity = 122/494 (24.70%), Postives = 197/494 (39.88%), Query Frame = 2
Query: 692 PNQTTDSITPDNCFYVP------VNSSLAKFPCTK----WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF-------AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGI-GSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEA---FEVLQILNQNSEDEDFNNKSIDDTETVHENKRFCHSKSLLIRL----GILLITSLSFYFV---YQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIG---SVTSVVIWTTIGLISYSIIPGN-WDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQFCFTESIGDKIVEEYK 2077
P Q S+ + F P S+ P K W FD S ST T+ LVC++R + + I+ +F A G LSD GRKPM L+ S + + + + + + + LRF GI G I+ VL+ E K R + + +S G + P WK + A P+ L + + ES +WLI+N + +A E I+N+ E + V E +S L+R + +T L++Y V Y G + N++ D+Y+N ++ G +EIPA L Y IG + V++ LI IP + W I S++ L K +A++ L +F L+PT R G + + ++ G + I +I S+I + L P LP T+E+ E +KD F + + +E +
Sbjct: 74 PRQEDGSLASCHMFAEPQFQFLGAKSNFTDVPLIKCPNGWIFDNSTFLSTLSTQWDLVCDKREMN------KAIATIFFIGVMLGAALFGSLSDRYGRKPMLLV-SYVLGMSFAVASVFSTSFIMFAVLRFFTGLGITGIVIVSSVLIVEWVDIKSRKLVGMIDSMSWSFGYMVLPAMAYGVRDWKWLTITATSPLILAIITWRWIPESARWLIANGKIKKAQFYLERCAIINKRKEATSSLKPEVLSC-IVSEGGSRKYSYLDLMRTPKMRRLAFLTGLTWYAVASTYYGISFNIKGFGLDLYLNQLLYGFVEIPAKILIYHMLDRIGRRRTEAGVLLLAGCNLIINVFIPKDQW-----------IVRSVIGVLGKGFASMAFSTLVLFSSELYPTVIRQ--NGMGWNSFMGRMGVAIAPLILLLDEIWGHMSQIILCAIAVIGSVIAYQL--PETRGRCLPETIEDVEGTRKDQDFTLIQKKAGEDLENGR 544
BLAST of slc22a-11 vs. Ensembl Cavefish
Match: SLC22A2 (solute carrier family 22 member 2-like [Source:NCBI gene;Acc:103036098]) HSP 1 Score: 85.5001 bits (210), Expect = 5.942e-17 Identity = 107/444 (24.10%), Postives = 190/444 (42.79%), Query Frame = 2
Query: 779 WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISG----VFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGI-GSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAF--PMFLYGLAPLILLESPKWLISNSRKDEAFEVLQIL---NQNSEDEDFNNKSIDDTETVHEN-KRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGS---VTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLI---ISMILFG----------LIIPSINKTSLPNTVEEAEQIKKDSQ 2029
W +D + +FVTE LVC+ W++ + + G V +I +G L+D GRK FL+ + + + IL+ I P++ SL +F R + FG+ G + VL+TE ++ F FS G+ + W+ WL AF P ++ + ESP+WL+S ++ A EV Q + N+ + ++ N D+ ET + + + IL + VYQG L +IYI+ +I G++E PA L + IG + I + + + IP + +L L + +AC+ + + +A+ ++ L+PT F+ N G + D GG +Y + +I + +I+FG L++P LP T+++ E ++ +
Sbjct: 126 WHYDYEH-RESFVTEFDLVCDD---AWLVDVFQAVLGIGFLVGSITIGYLADKFGRKMSFLLSNILNAVTGILVAISPNYISLVVF-RALHGFGVKGGWMAAYVLMTETVGVLFQMF--------FSFGLLLLALIAYLIPNWR--WLQVAFTVPYIIFLSYYWFVPESPRWLLSQNKSSRAVEVTQAMAKENKKTLSQNIKNLKDDNAETSTGSFMDLIRTPKIRKHTLILSFNWFTSAVVYQGLIMRLGILRGNIYIDFLISGIVEFPAAFLILFTIERIGRRLPFAAANIVSGAACLITAFIP---ESVLWL-------KTAVACIGRLGITMAFEMVVFVNTELYPT----FIRNLGVSVCSTLC------------DIGGIIAPFLLYRLAVIWLELPLIIFGVLAFVAGGLVLLLPETKGVPLPETIDDIEYPNRNKE 528
BLAST of slc22a-11 vs. Ensembl Sea Lamprey
Match: oct2 (organic cation transporter 2 [Source:ZFIN;Acc:ZDB-GENE-080204-92]) HSP 1 Score: 104.375 bits (259), Expect = 1.112e-23 Identity = 126/495 (25.45%), Postives = 207/495 (41.82%), Query Frame = 2
Query: 680 QCLSPNQTTDSITPDNCFYVP---------VNSSLAKFPCTK-WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISG-VFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIK-LFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAM---TPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVL-QILNQNSEDEDFNNKSIDDTETVHENKRFCHSKSLLIRLG-------ILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIG-LISYSIIPGNWDPMLNLTQTGKISHSI------LACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFI----YGILLIISMILFG----------LIIPSINKTSLPNTVEEAEQIKKDSQF 2032
QC+ N TT S + C P V+ S C W+FD K T V+E LVC +L + L N+ V AI +G +SD GR+ ++ TI +L+ P +Y+ + +R ++ +F +GS V TE R + + FS G+ M +Y++ + Y + + + +F Y +L ESP+WLIS +RK++AF VL +I + N + N + + T + K S + L+R +L+I VYQG A + D+Y+ ++ GL EIP G++ + + +G + + PG L T + H I L L + L +A+ ++++ L+PT+ RN + S G A F+ Y I + M++FG L++P N LP T E+AE I K+ +
Sbjct: 88 QCMRVNTTTWSDSNAPCGLAPWGQGDEVPNVSFSGRLIACDHGWEFDTEKTGLTLVSEFDLVCENAWLLDLSQALLNVGLLVGAILMGYVSDRYGRRWSLMVSIVMQTIFGVLVAFAP-NYAAFVCMRTLQGIFNMGSWTTVFVTATEFVGSGQRRVVHMVLQMFFSFGVIMLSGIAYYLRTWRYLQLALTLPNVVLFSY---YWLLPESPRWLISQNRKEQAFGVLKKIASVNGRELSDNIRKNFEEVTRADEKAGNPSIADLMRSAKIRKYTVVLMIYWFVVGVVYQGLAMSTGNIGDDVYLAFLMGGLAEIP------------GALMVIALIDRVGRRLPMCVAPG--LSGLACLATALVPHDIGWLNITLVTLGRLGLTMAYEMVTLVNNELYPTHLRNMAMS-----------------TCSSLSGIGGIVAPFVLYRLYTIWRHLPMVIFGTLAIIGGFVILLLPETNGLPLPETTEDAENISKNQKM 547
BLAST of slc22a-11 vs. Ensembl Sea Lamprey
Match: si:dkey-190l8.2 (si:dkey-190l8.2 [Source:ZFIN;Acc:ZDB-GENE-030131-9103]) HSP 1 Score: 63.5438 bits (153), Expect = 6.482e-11 Identity = 76/323 (23.53%), Postives = 136/323 (42.11%), Query Frame = 2
Query: 890 VFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVT-----ELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQ---ILNQNSE--------DEDFNNKSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIG----LISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKR 1798
V +I +GI SD GR+P+ L C S ++ LP ++ ++ R + G++ G++L + E R + I FS+GM K W Q L P + L L ESP+WL R EA +L+ I+N+ SE + + +++ + + K LLI I S+++Y + +F + DI++ + GL EIP L L +G + +++ ++ L+ + P + ++ L GK+ + AC++ +++ + LFPTN R
Sbjct: 31 VGSIAMGIASDRYGRRPVLLGCVASQGAAEFVIAFLP-NFPTYLLGRLLT----GTTASGIMLCSFSLGVEWCGPALRAWPPIILALAFSVGMMALAGVAKISQNWPQLHLATGVPQLMVLLLFWSLPESPRWLFLKKRTTEARNLLRQASIINRRSEVSWTPLRLTSKLSTRGANESTLLITFRNRTLRKRLLIMSYICAAVSMTYYGLCLSVG---DFGL-DIHMAQFLSGLAEIPQLLLPPLMR-RVGRRSLCIVFLSVAGATCLLCLPLQPNLANVVVALALLGKLCAQVTACVA-----------TLYRIELFPTNVR 332
BLAST of slc22a-11 vs. Ensembl Sea Lamprey
Match: SLC22A7 (solute carrier family 22 member 7 [Source:HGNC Symbol;Acc:HGNC:10971]) HSP 1 Score: 60.4622 bits (145), Expect = 4.734e-10 Identity = 54/232 (23.28%), Postives = 103/232 (44.40%), Query Frame = 2
Query: 725 NCFYVPVNSSLAKFPC-TKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVT-----ELTPKKYRNFIIIN---YWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDTETVH 1387
N P+ +S PC + W++D+ + T VT+ LVC + L + + L ++GV ++ G LSD GR+ L + + PS +S +RF+ +G S+ G+++ T E + +R F + WS ++ + + + ++ W+Q L+ P++ L + ESP+WL+ R EA L + + + F ++ + H
Sbjct: 96 NASESPLRNSSEAVPCPSGWEYDRRQFTETVVTQWDLVCEHKALNHLSLTL-FMAGVMLGSLVFGYLSDRYGRRNALLGSYVLNAVTGTAAAWAPS-FSSFTAMRFL----LGVSLSGIIVNTLSLSVEWLDQGHRTFAGTSGGFAWSTGNMALGLLAYLLR---GWQQLQLVVTSPIYFCILTWWFIPESPRWLLVRGRAREAHRNLSLCARINGRTKFGSEVTVEARGWH 318
BLAST of slc22a-11 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007122.1 (pep scaffold:Pmarinus_7.0:GL476962:153150:164773:-1 gene:ENSPMAG00000006444.1 transcript:ENSPMAT00000007122.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 50.8322 bits (120), Expect = 3.841e-7 Identity = 46/162 (28.40%), Postives = 72/162 (44.44%), Query Frame = 2
Query: 767 PC-TKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNIS-GVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSII-GLVLVTELTPKKYRNFIIINYWSVFSIG---MAMTPWYIKRFAYWKQSWLIAAFPMFLY 1234
PC T W +D+S ST VTE LVC + +L + + + V A LG ++D GRK + L+ T + P ++ ++ RF+ I I+ VL TE T R I F +G +A ++I+ W+Q L + P L+
Sbjct: 94 PCATGWDYDRSVFTSTVVTEWDLVCTRSYLNNVGSSIFMLGLMVGAPVLGTMADKYGRKSVILVSMAIQTAFGLGAAFAP-NFVMYALARFMVGVAISGVIMNAFVLATEWTGIGERMLAGIATQQAFGVGYMLLAPVAYFIRD---WRQLQLAISIPEILF 251
BLAST of slc22a-11 vs. Ensembl Yeast
Match: HXT3 (Low affinity glucose transporter of the major facilitator superfamily; expression is induced in low or high glucose conditions; HXT3 has a paralog, HXT5, that arose from the whole genome duplication [Source:SGD;Acc:S000002753]) HSP 1 Score: 48.521 bits (114), Expect = 3.106e-6 Identity = 63/281 (22.42%), Postives = 122/281 (43.42%), Query Frame = 2
Query: 896 AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGS-SIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAM---TPWYIKRFA---YWKQS-WLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDTETVHENKRFCHSKS----------LLIR--LGILLIT----SLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPA-----------GPLGYLSSIAIGSVTSVVIWTTIGL 1633
I L L DM GRK ++ I I+ + + + R I G+G +++ +L++E+ PK+ R ++ Y + ++G+ + T + K ++ W+ L A+ +F+ G + ESP++L+ + DEA L +N+ + D F + ++ E E R S S + R +GI++ + + YF Y GT +SD + +++ G++ + G L AIG V V++ ++G+
Sbjct: 127 GIILAKLGDMYGRKMGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVAPKEMRGTLVSCYQLMITLGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVP-ESPRYLVEAGQIDEARASLSKVNKVAPDHPFIQQELEVIEASVEEARAAGSASWGELFTGKPAMFKRTMMGIMIQSLQQLTGDNYFFYYGTTVFNAVGMSDSFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLLYGAIGMVCCYVVYASVGV 406
BLAST of slc22a-11 vs. Ensembl Nematostella
Match: EDO36723 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHW3]) HSP 1 Score: 84.7297 bits (208), Expect = 3.063e-17 Identity = 105/411 (25.55%), Postives = 170/411 (41.36%), Query Frame = 2
Query: 647 MSMFLYYTPKYQC-------LSPNQTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKS----TFVTELKLVCNQRFLQWILIPLRNIS-GVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGL-VLVTELTPKKYRNFIIINYWSVFSIGM---AMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFY------FVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLIS---YSIIPGNWDPMLNLTQTGKISHSILA-CLSKFSLVVAWNILSVFYVALFPTNKRN 1801
+ +F+ Y P + C L N T I + + + K T WKF ++ T VT+ LVC+ F W+ + + AI LG+++D GR+ + + I + + + + I LRF F +G SI+ + VL EL R W F++ + + ++IK WK +I+ P + + ES +WL+ RKD+A E+L+ + + ++ E K V N+ F L + L+T L Y VY + + IY+N ++ ++E PA L + G +VV +T +G IS S IP D G I+ + A L K + ++N L VF LFPT RN
Sbjct: 39 LMVFVAYEPPWMCTTNSSACLLSNSTGREIYSTSTQPIELYHRRCKLNRTDWKFADPELYEGPVHTIVTQFDLVCDNSFHAWLANSMLFFGWALGAIILGMIADKYGRRSVLFPSAACVIAITFSMSFAQASWVV-IALRFFSGFFLGGSILTMFVLAAELVGPAKRALSSTMVWFYFTLALMVLGLQAYFIKD---WKLLCIISTVPFVFIFIFWKFIPESVRWLLVVGRKDQAREILEQVAKVNKKE--MPKEDLRVPVVKHNRGFLE---LFGTPRLALLTLLQCYAWLVNGLVYYAVSMSAGDFGGSIYLNFVLTSIVEFPANILVIDNCNRFGRKHTVVWYTVVGAISCLVVSFIPSGTD------NIGYIAGRVAAGTLGKLCITTSFNSLYVFSAELFPTMIRN 434
BLAST of slc22a-11 vs. Ensembl Nematostella
Match: EDO46087 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR13]) HSP 1 Score: 80.4925 bits (197), Expect = 6.039e-16 Identity = 110/512 (21.48%), Postives = 208/512 (40.62%), Query Frame = 2
Query: 596 IYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSII-GLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEV-LQILNQNSEDEDFNNKSIDDTETVHEN----KRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWT--TIGLISYSIIPGNWDPMLNLTQ-----TGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFS--FANFIYGILLIISMILFG----------LIIPSINKTSLPNTVEEAEQIKKDSQFCFTESI 2050
+Y ++ +S+ + + + +F+ P + CL N +T+ P N K CT+ ++ ++ +TE LVC + + L+ +SG A+ G L+D GR+ ++ + P+ + ++ LRF+ F IG I+ VL TEL YR F I F++G+ + P W+ ++ + P ++ L + ES +WL+ R EA + L I +N + ++ V FC ++ ++ + +L+ VY G + N + DIY+N + L+E PA YL+ + V W L +Y ++ G Q + ++ A + KF + ++ ++ ++ +FPT RN G + S+ GG F F+ + + M++FG L++P +K LP T+++ DS F + + +
Sbjct: 20 LYVLLCLSIVPAAIQLLLLVFVAAQPHWICL--NSSTNETCPKN-----------KLQCTERQYTSKY--TSIITEWDLVCENAY-KADLVQSLLMSGTLLGALMFGALADKYGRRRVWHTTLTGLVVFGFASSFAPT-FKIYATLRFLTGFCIGGEILSAFVLATELVGPSYRGFAGIMAQCFFTLGLLILPMVAYLIQDWRTLSVVLSLPASVFILFFRYVPESARWLMIRGRVSEAENILLDIALKNGIAVPKSLLQVNHPFFVGSRYGFFDLFC-TRKIVKQTFVLIFIWFVNTLVYYGLSLNTKHLAGDIYMNFFLCSLMEFPA----YLTCLFF------VNWAGRRKTLFNYMVLAGLACMACMFVQPESSPADRTLATVFAMIGKFGITASFALIYIYSAEIFPTVVRN--VGLGVCS--------------MSSRIGGICAPFVVFLGTYMRPLPMVIFGMCAFMAGLLSLMLPETHKRPLPETMDDKMFKANDSDFEYDDDL 487
BLAST of slc22a-11 vs. Ensembl Nematostella
Match: EDO41816 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3A3]) HSP 1 Score: 74.3294 bits (181), Expect = 7.218e-14 Identity = 131/531 (24.67%), Postives = 223/531 (42.00%), Query Frame = 2
Query: 593 LIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGI-LPSHYSLHIFLRF-IKLFGIGSSIIGLVLVTELTPKKYRNF---IIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEV-LQILNQNSE--DEDFNNKSIDDTETVH------ENKRF-----CHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYL----SSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVAN---FGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKD-SQFCF---------TESIGDKIVEE 2071
L+Y +S V + + + +F P++ C N T P++ N A CT + +++ + ST VTE L+C++ +L I +G+F AI G LSD GRKP I G + + LG SL LRF I F + ++ V E+ KYR + +W A+ ++I+ W+ + + P L+ L I SP+WLI+++R DEA + L+ +++S+ DE + I+D ++KR+ + L R IL T + V+ G + ++Y N +IM +I P LG++ ++ SV SV + + + S++ + ++ I A L K + + ++ LFPT R +N G T +G + + N G I+G+L ++ I+ L +P L TVEEAE K+D S C+ E +GD +++
Sbjct: 35 LLYLSMSFLVTLMAMQYGLLVFAMGPPRFYCADVNSTC----PED------NVCCAN--CTTYAYEEGQFTST-VTEWDLLCDRAYLA-ATIQSCYFAGMFFGAITGGWLSDNFGRKPTMFI--GVGVMALVSLGSSFSDAISLLSLLRFVIGFFQMVLNVTYFVYAIEILGPKYRTLGGQLCSLFWLFGYSTTAVFAFFIRD---WRMLIVAVSIPGLLFVLLWKIFPASPRWLIAHNRLDEAHSILLKFGSRDSKPIDEQALRELIEDVRRDQLERHKMDDKRYTMMDLVRTPKLRKRSFILFYTWVVCAIVHFGFFLYVTSLTGNLYSNYVIMNVITFPKA-LGFIYVMNKVLSKSSVISVRVTGESSVTTESVLGKS-----------SVTTEIFAMLGKSFMSAQFLNAFLYGTELFPTVVRLVTSNAIGCGTMTSRLGGMLTPYIAMLGQLPNYGVYVPATIFGVLTLVGAIM-SLWLPETLFAKLSQTVEEAEAAKEDFSIICWGHHKRRKREAEDLGDDYIKD 533
BLAST of slc22a-11 vs. Ensembl Nematostella
Match: EDO36696 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHW2]) HSP 1 Score: 70.0922 bits (170), Expect = 1.329e-12 Identity = 99/410 (24.15%), Postives = 168/410 (40.98%), Query Frame = 2
Query: 653 MFLYYTPKYQC-------LSPNQTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKS----TFVTELKLVCNQRFLQWILIPLRNIS-GVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGM---AMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDTETVHENKRFCHSKSLL-----IRLGILLITSLSFYFV----YQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIG---LISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRN 1801
+F+ Y P + C L N T I + + + K T WKF ++ T VTE LVC+ F W+ + + AIFLGI++D GR + + + + + + + + + FI F G + VL TEL R W F+ + A+ ++I+ W +I+ P L + ES +WL+ K +A +L+ + + N KS+ + E H++ ++ RL +L + +FV Y G + + IY+N ++ L+E PA L + G +VV +T IG I+ S IP + + + G+++ +L K + ++N L VF LFPT RN
Sbjct: 41 VFVAYEPPWMCSTNSSACLLSNSTGREIYSTSTQPIELYHRRCKLNRTDWKFADPELYEGPVHTIVTEFDLVCDHSFTAWMANSMLFFGWAIGAIFLGIIADKYGRCSVLFPSAILVMGLSLAMAFVKKAWLVLVLRFFIGFFEGGGFLSMFVLATELVGPAKRALAGTLVWIYFTAALMVLALKAFFIRD---WSTLCIISIAPFVFIVLFWKFVPESVRWLLVTGSKGKARRILENVAR------VNKKSMPEEELFAPQVE--HNRGIIELFSTKRLAVLTLLQCYAWFVNGMVYYGVSMSAGDFGGSIYLNFVLTSLVEFPANVLLIHNCNRFGRKRTVVAYTLIGAIACITVSFIPAGTNNLGFI--IGRVTGGMLG---KLCITTSFNGLYVFSAELFPTMVRN 434
BLAST of slc22a-11 vs. Ensembl Nematostella
Match: EDO42875 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZZ3]) HSP 1 Score: 66.6254 bits (161), Expect = 1.963e-11 Identity = 95/379 (25.07%), Postives = 156/379 (41.16%), Query Frame = 2
Query: 563 MEEIINL---RLFLIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSIT----PDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFA------IFLGILSDMKGRKPMFLICSGS-DTIIWILLGILPSHYSLHIFLRFIKLFGIG-SSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILL-----ESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDD--------TETVHENKRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVI 1615
+EEI ++ ++ L++ F G + F+ P +QC+ N T ++T P Y P + W+F K + ST VT+ LVC Q + + S +FA IF+G LSD GR+ +++ GS + ++ L + L + R I IG SS+ +L+TE ++RN W ++ TP FAY+ + W I + + G+ P ES +WL+ R EA +L+ + FN K + D V + + ++ ++ R IL L VY G + + +Y+N + ++EIPA S G SVVI
Sbjct: 9 LEEIGSMGRYQIRLVFIFCYFGFFVVGFQTMLMTFITGEPGWQCVE-NSTVCNVTGVHRPGGDHY----KLRCDLPRSDWEFAK-EFTST-VTQWDLVCEDSIFQGV-----SSSVIFAGWLLGAIFIGWLSDRTGRR--YVVYFGSLGLLAAAVVSALSPFFWLFVLSRAIVGVMIGGSSLCQFILMTEFVGVRHRNVAATLVWFAWTCAFMATP----LFAYFIRDWRILTIAVTVTGV-PFSFFWWFIPESMRWLLVKGRVTEAEAILR------DVAAFNRKKMPDEGLLEPLNKGKVADFRDLFRNRKMVQRTLILWFAWLVNAMVYYGVSLSSPSLGGSMYLNFFLTSIVEIPANFAAIYSMKRFGRKKSVVI 362
BLAST of slc22a-11 vs. Ensembl Medaka
Match: slc22a2 (solute carrier family 22 member 2 [Source:NCBI gene;Acc:101173762]) HSP 1 Score: 101.679 bits (252), Expect = 4.563e-22 Identity = 108/449 (24.05%), Postives = 201/449 (44.77%), Query Frame = 2
Query: 779 WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISG-VFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGI-GSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDE--------AFEVLQILNQNSE---DEDFNNKSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFY---FVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLI---ISMILFG----------LIIPSINKTSLPNTVEEA---EQIKKDSQ 2029
W++D + +FVTE LVC+ ++ + N+ V +I +G L+D GRK FL+ + + + IL+ + P++ SL +F R + FG+ G + G VL+TE+ ++R + + Y FS+G+ + P W+ L P L+ + ESP+WL+S ++K + A E ++L++N E D+D ++ S + + H+ LI S +++ VYQG L ++Y++ +I GL+E PA L + IG + S I D + L +++AC+ + + +A+ ++ L+PT FV N G + D GG +Y + +I + +I+FG L++P LP+++++ E++K+++Q
Sbjct: 121 WEYDYEG-RQSFVTEFDLVCSHGWMADMFQATLNVGFLVGSIAIGYLADRFGRKMSFLMSTLVNAVAGILVAVSPNYTSLLVF-RSLSGFGVKGGWMAGYVLITEIVGVEFRRTVGVLYQMFFSVGLLILPLLAFFITDWRWLQLAITAPYILFLSYYWFIPESPRWLLSQNKKSQVVKITESIAKENRRVLSKNIETLTDDDADSNSASFMDLIRTPNMRKHT----------LILSYNWFTSAVVYQGLIMRLGILGGNVYVDFLISGLVEFPAAFLILFTIERIGRRLPFASANMVAGASCLITAFLPDDLFLL-------KTVVACIGRLGITMAFEMVVFVNTELYPT----FVRNLGVSVCSTLC------------DVGGIVAPFLLYRLAVIWLELPLIIFGFLAFLAGGLVLLLPETRGVPLPDSIQDVEFPERVKQEAQ 534
BLAST of slc22a-11 vs. Ensembl Medaka
Match: slc22a7a (solute carrier family 22 member 7 [Source:NCBI gene;Acc:101169334]) HSP 1 Score: 93.2041 bits (230), Expect = 2.034e-19 Identity = 92/316 (29.11%), Postives = 148/316 (46.84%), Query Frame = 2
Query: 692 PNQTTDSITPDNCFYVPVNSSLAK----FPCTK-WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVF-AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINY---WSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVL-QILNQNSEDEDFNNKSIDDTE-----TVHENKRFCHSKSLLIR---LGILLITSLSFYFVYQGTATNLEFAIS----DIYINAMIMGLIEIPAGPLGY 1573
P + S + F +P++S+L++ PC W FD++++ ST +E LVCN++ L L + F AI G LSD GRK M L+ S T++ S+ + + G SII +VL E T K+R F I WSV ++ +A+ ++I+ W+ L+ P+ L ++ L ES +WL+++ R +EA + L Q N ED + DTE TV E + H+ L++ L + + S F+F + F IS +IY+ I G +E+PA L +
Sbjct: 74 PQEEDGSFSSCRAFELPLSSNLSRANGTVPCQHGWIFDQTELSSTTSSEWDLVCNEKNLNQALATYFFLGVTFGAIVFGQLSDKFGRKSMILVAFISSTLLGATSAFSTSYVMFAVSRALCGMALSGMSIISVVLGIEWTDIKHRTFTTIITGLSWSVGNMLLALLAFFIRD---WRHLTLVVTAPIVLTIISWWWLPESARWLLTHGRTEEAKKYLVQCAKMNGRKED---TAKLDTETLAKITVSEVAKKKHTYLDLVKTPQLRKITLCSGFFWFAVAFLYYGISFRISGFGVNIYLTQFIYGAVEVPAKILAF 383
BLAST of slc22a-11 vs. Ensembl Medaka
Match: si:dkey-166k12.1 (solute carrier family 22 member 13 [Source:NCBI gene;Acc:101165571]) HSP 1 Score: 89.3521 bits (220), Expect = 3.473e-18 Identity = 102/412 (24.76%), Postives = 187/412 (45.39%), Query Frame = 2
Query: 647 MSMFLYYTPKYQCL------SPNQTTDSITPD-NCF---YVPVNSSLAKFPCTK-WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISG--VFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGL-----VLVTELTPKKYRNF--IIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFYF-------VYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRN 1801
+S+F TP +QC + NQT + PD +CF +P + + PC + W + +S+ VTE LVCN+ L + + +SG V ++ G ++D GR+ + L+ T+ + + P ++ +++ LRF +G++I G+ VL TE T K R II +Y F +G + W++ L + P FL +L +S +WL++N R +EA +L+ + ++ E + +KR HS L+R + ++ ++ VY G + + +++Y+ + GLIEIPA L L + S+ + +G ++ + ML + + + LA + KF + ++ I+ V+ +FPT R
Sbjct: 37 VSIFTGATPPHQCRDSFSTGAGNQTLNLSLPDASCFSADALPPGNRTERVPCGRGWVYSSEVFESSTVTEWDLVCNRAGLNSLGSSV-YMSGLLVGSVVFGAMADRYGRRFVLLLSIALQTVFGVAVAFAP-NFPVYVLLRF----AVGTTISGVIINAFVLGTEWTCTKRRMLAGIITDY--TFGLGYMLLAGVAYLIRDWRKLQLAISAPGFLLIFYIRVLPQSARWLLANDRTEEAIALLRKAALVNGRVLPPAVQVEKWEILGGSKR-SHSAVDLVRTPQMRKRTVILFYIWFVNVLVYYGLSLGVSRLGTNLYMTQFVFGLIEIPARSL-VLIFLPFSRRLSLSGFLAVGGLACLL-------MLTVPEDHPNVLTGLAMVGKFGITASFAIIYVYTAEIFPTVVRQ 431
BLAST of slc22a-11 vs. Ensembl Medaka
Match: ENSORLT00000027238.1 (solute carrier family 22 member 5 [Source:NCBI gene;Acc:101164738]) HSP 1 Score: 84.7297 bits (208), Expect = 9.119e-17 Identity = 104/450 (23.11%), Postives = 187/450 (41.56%), Query Frame = 2
Query: 779 WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRN---ISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFG-IGSSIIGLVLVTELTPKKYRN-FIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQ----NSEDEDFNNKSIDDTETVHENK------RFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQFCFTESIGDKIVEEYK 2077
W + K +ST VTE LVC +++ Q P + GV + F G LSD GRKP+ + TI + L + + + I L FI G I + + LVL E+ R + + F++G + P WK L + P Y IL ESP+WL+S R EA V+++ + + F S++ T+T E+ R ++ + L +L T ++ Y+ + L +D YI+ I L+EIPA +++ S+++ G + +IP + + +L+ T L +SK+S +++ + L+PT RN +G+ I F + + + ++ L + + +P K LP T+E+ + ++ C +I +++ +
Sbjct: 116 WVYSKDIYQSTIVTEFDLVCTEQWKQ----PFTSTIFFVGVLLGSFFSGPLSDRFGRKPVLFATMAAQTI-FTFLSVFTTTWIWFIILLFINGLGQISNFVAALVLGAEIFTGNVRVLYSSMGTCCGFAVGYMLLPLCAYFLRDWKSLLLALSVPCVAYIPLWWILPESPRWLLSQGRIAEAEAVVKMAAKWNKVQAPSNIFECNSVEKTDTQKEHYNVFDLLRHSRIRTTTLLLCFVLFTLITGYYCLSFNTSQLH---TDPYISCFISALVEIPAYASSFIALRYFPRRLSIIVSLIAGAVPLYLIPLVPEHLSSLSLT-------LEMVSKYSFTTGASLMFAYTTELYPTVLRNTATGTTTTISRMGSCITPFLLSLSVH----YKYLPYVILATLAVVTAISAYFLPESFKLPLPETIEQMHERQRKIHLCNKRNISPVSLDDSR 546
BLAST of slc22a-11 vs. Ensembl Medaka
Match: ENSORLT00000001522.2 (solute carrier family 22 member 5 [Source:NCBI gene;Acc:101164738]) HSP 1 Score: 83.9593 bits (206), Expect = 1.571e-16 Identity = 92/358 (25.70%), Postives = 155/358 (43.30%), Query Frame = 2
Query: 779 WKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRN---ISGVF--AIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFG-IGSSIIGLVLVTELTPKKYRN-FIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQ----NSEDEDFNNKSIDDTETVHENK------RFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRN 1801
W + K +ST VTE LVC +++ Q P + GV + F G LSD GRKP+ + TI + L + + + I L FI G I + + LVL E+ R + + F++G + P WK L + P Y IL ESP+WL+S R EA V+++ + + F S++ T+T E+ R ++ + L +L T ++ Y+ + L +D YI+ I L+EIPA +++ S+++ G + +IP + + +L+ T L +SK+S +++ + L+PT RN
Sbjct: 116 WVYSKDIYQSTIVTEFDLVCTEQWKQ----PFTSTIFFVGVLLGSFFSGPLSDRFGRKPVLFATMAAQTI-FTFLSVFTTTWIWFIILLFINGLGQISNFVAALVLGAEIFTGNVRVLYSSMGTCCGFAVGYMLLPLCAYFLRDWKSLLLALSVPCVAYIPLWWILPESPRWLLSQGRIAEAEAVVKMAAKWNKVQAPSNIFECNSVEKTDTQKEHYNVFDLLRHSRIRTTTLLLCFVLFTLITGYYCLSFNTSQLH---TDPYISCFISALVEIPAYASSFIALRYFPRRLSIIVSLIAGAVPLYLIPLVPEHLSSLSLT-------LEMVSKYSFTTGASLMFAYTTELYPTVLRN 458
BLAST of slc22a-11 vs. Planmine SMEST
Match: SMESG000027294.1 (SMESG000027294.1) HSP 1 Score: 947.577 bits (2448), Expect = 0.000e+0 Identity = 491/507 (96.84%), Postives = 491/507 (96.84%), Query Frame = 2
Query: 557 MAMEEIINLRLFLIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQFCFTESIGDKIVEEYK 2077
MAMEEIINLRLFLIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQT VVAWNILSVFYVALFPTNKRNFVANFGEATGFIGAAIGGFAGYYYSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQFCFTESIGDKIVEEYK
Sbjct: 1 MAMEEIINLRLFLIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQT----------------VVAWNILSVFYVALFPTNKRNFVANFGEATGFIGAAIGGFAGYYYSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQFCFTESIGDKIVEEYK 491
BLAST of slc22a-11 vs. Planmine SMEST
Match: SMESG000027294.1 (SMESG000027294.1) HSP 1 Score: 945.266 bits (2442), Expect = 0.000e+0 Identity = 490/507 (96.65%), Postives = 490/507 (96.65%), Query Frame = 2
Query: 557 MAMEEIINLRLFLIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQFCFTESIGDKIVEEYK 2077
MAMEEIINLRLFLIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQT VAWNILSVFYVALFPTNKRNFVANFGEATGFIGAAIGGFAGYYYSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQFCFTESIGDKIVEEYK
Sbjct: 1 MAMEEIINLRLFLIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSITPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSEDEDFNNKSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQT-----------------VAWNILSVFYVALFPTNKRNFVANFGEATGFIGAAIGGFAGYYYSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQFCFTESIGDKIVEEYK 490
BLAST of slc22a-11 vs. Planmine SMEST
Match: SMESG000004219.1 (SMESG000004219.1) HSP 1 Score: 156.377 bits (394), Expect = 2.133e-40 Identity = 119/428 (27.80%), Postives = 206/428 (48.13%), Query Frame = 2
Query: 590 FLIYFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPN------QTTDSITPDNCFY-VPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYS-LHIFLRFIKLFGIGSSI---IGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQILNQNSE----DEDFNN-KSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIP--------GNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRN 1801
++ + +S++ F+ V+FQ F Y PK+ CL N +T+ I+ D C Y + VN S K C +W F+K +++T + EL LVC++ F + ++ + +F+ ILSD G++ + ++ TII I G + S+ + L F+ G+ S+ + + E+ P + + N+W+++S G + + F W+Q ++++ Y L + E+P+WL+ N R++EAF+ + + + ++ E+FN K I N K+++ R IL +F F Y G+AT+L FA +I+I +MGLIE+P GPL + + +G SV + +G+I I+P W P L + LA +K AW I + L PT RN
Sbjct: 18 YISFMTLSITTFKYVVEFQGLTFALYEPKFSCLVKNISSTIRNSTNLISKDQCQYRLSVNDSWNK--CDQWTFEKRFMRNTLINELNLVCDRAFYRELIFTTFFVGCLFSFPFSILSDSIGKRLLLIVSIFLSTIITI--GQMVSYQIWQQLVLSFVS--GVCKSVYVSLAYTTLIEIIPVSHIDLAATNFWNLYSFGYMLVALFAYIFRSWRQIYILSLITSIFYVLYFWFVPETPRWLMLNKRRNEAFKTMSFIAKINKCTLNKEEFNKWKPIQQVTGKFWN--LLKHKTMIYRFLILNFAGWAFSFAYIGSATDLTFASENIFITTFVMGLIELPTGPLSGIMANKLGRKKSVSALSGLGIICLIIMPFIEADSLKSVWQPWLKVC---------LAMGAKLGFSSAWLIFDIITNELIPTTDRN 428
BLAST of slc22a-11 vs. Planmine SMEST
Match: SMESG000025785.1 (SMESG000025785.1) HSP 1 Score: 123.25 bits (308), Expect = 2.899e-29 Identity = 128/498 (25.70%), Postives = 214/498 (42.97%), Query Frame = 2
Query: 599 YFIISVSVFQSGVDFQMSMFLYYTPKYQCLSPNQTTDSI--TPDNCFYVPVNSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWLISNSRKDEAFEVLQ-ILNQNSEDEDFNNKSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFYFVY------QGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIG--LISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANFIYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQFCFTESIGDK 2059
+ I+S+ FQ G FQ + TP + C N+T+ I + D C + +N S K C W F T +++ LVC+ +++ +L+ L + + A G L+D GRK + +I +T+ +L P+ YS HIF R F + I V + E+ K +RN +W S+ M + P + W+ + LI+ P LY L L + ESP+WL ++K + E LQ I N N D + I +T E ++ K + L + S S + V+ +L S+IYI+ ++GL+E P L YLS + I++ G I S+ D + I I + K ++ + + V+ LFPT R+ FG + A+ N GF IY +L +IS L + +P +P T+ + + K+ + + E + ++
Sbjct: 21 FLILSLPAFQYGSQFQNLLVSIRTPNFTC-QYNETSHQIQISKDQC-TMTINGSNVK--CQHWTFSSEPFGETIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLYS-HIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLI-LFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPEEIKIEKTTKEWNKWNAFKD----MNFLFLASTSLFAVFSISILISAILIDLNLLSSNIYISMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVD------KWQSIFRMIFGSIGKVLVMTSSQGVLVYATELFPTTHRSLF--FGMLQIILLMAMTAAVYINKLNQFYGF-IPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNR 499
BLAST of slc22a-11 vs. Planmine SMEST
Match: SMESG000064528.1 (SMESG000064528.1) HSP 1 Score: 121.324 bits (303), Expect = 1.137e-28 Identity = 130/508 (25.59%), Postives = 229/508 (45.08%), Query Frame = 2
Query: 548 NFRMAMEEIINLRLFLIYFIISVSVFQ--SGVDFQMSMFLYYTPKYQCLSP--NQTTDSITPDNCFYVPV--NSSLAKFPCTKWKFDKSKIKSTFVTELKLVCNQRFLQWILIPLRNISGVFAIFLGILSDMKGRKPMFLICSGSDTIIWILLGILPSHYSLHIFLRFIKLFGIGSSIIGLVLVTELTPKKYRNFIIINYWSVFSIGMAMTPWYIKRFAYWKQSWLIAAFPMFLYGLAPLILLESPKWL-ISNSRKDEAFEVLQILNQNSE---DEDFNNKSIDDTETVHENKRFCHSKSLLIRLGILLITSLSFYFVYQGTATNLEFAISDIYINAMIMGLIEIPAGPLGYLSSIAIGSVTSVVIWTTIGLISYSIIPGNWDPMLNLTQTGKISHSILACLSKFSLVVAWNILSVFYVALFPTNKRNFVANFGEATXXXXXXXXXXXXXXXSNDNGGFSFANF----IYGILLIISMILFGLIIPSINKTSLPNTVEEAEQIKKDSQ 2029
N+ A+ EI F + ++++S+ S +D +F+ +TP Y+C+ P NQT + T C + N + C WK++K+ + +T TE LVCN++ ++ + + F+ I D GR + + + II I L ++ L I LRF+ G G GL +TE+ K R+ NYW ++ +G + P W+ S + FP+ Y L +L ESP+WL I K +L I N + + F++ I + + F SK + +++ +L+ + Y G + N F S+I++N I GL+E GP+ ++ S + S++I + S ++ N+ N+ + I S L + KF+L A+ I ++ +FPT RN + FI I + + NG F + Y ++ +IS +L +P LP T+EE +++K ++
Sbjct: 2 NYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLP-FATNIWLIILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNFPLLFY-LTYFLLPESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGNITDIF-GSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLI--NFLICSVCLMLNNFYSFNNIIVS--IVISTLGSIGKFALTTAYCICDMYLNEVFPTPIRNM-------SIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNE 495 The following BLAST results are available for this feature:
BLAST of slc22a-11 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of slc22a-11 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of slc22a-11 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of slc22a-11 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of slc22a-11 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of slc22a-11 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of slc22a-11 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of slc22a-11 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of slc22a-11 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of slc22a-11 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of slc22a-11 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of slc22a-11 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of slc22a-11 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of slc22a-11 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30010312 ID=SMED30010312|Name=slc22a-11|organism=Schmidtea mediterranea sexual|type=transcript|length=2144bpback to top protein sequence of SMED30010312-orf-1 >SMED30010312-orf-1 ID=SMED30010312-orf-1|Name=SMED30010312-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=527bp MFTFSEIFFIRYKHLTNFRMAMEEIINLRLFLIYFIISVSVFQSGVDFQMback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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