Lamin-B2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30010297 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10
Homology
BLAST of Lamin-B2 vs. Ensembl Human
Match: LMNA (lamin A/C [Source:HGNC Symbol;Acc:HGNC:6636]) HSP 1 Score: 93.9745 bits (232), Expect = 1.394e-19 Identity = 122/526 (23.19%), Postives = 230/526 (43.73%), Query Frame = 1
Query: 91 RKSTNSSLNAS-----------FADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNY----------RKKLEG-YEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEK--------------SILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQD---KLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNIS---------------------GVTTPKRRKINNDDTDDKFQINAYTNDAMKL-FCDEEYNGGHIKLLNDSDKLININEWKLTII-TDDSTSVYCFPDK-NIDSKQTLQIWTVD-----SPVMDDV 1437
R++T S AS +KE++ D LA YID VR++E N L+ E +++ IK+ Y E+ RK LD +A +L LE ++EE L + + L A + + +L+ +++ ++ LEG L+ + + + + K L++E+ + V+ ENR T+ EE+DF K + + +K ET I N + + + ++ L+ Q + E +++LEK Y K + ++ E+ S +R ++L + S L++++ AK+ ++ L + + RE D + + + R + + ++ ++ E +L+D K+AL+ E + + LLEGE+ R +S G + K+RK+ + ++ F +A T+ + + DEE G ++L N S++ ++ W++ DD Y FP K + + Q + IW SP D V
Sbjct: 7 RRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQL-------AAKEAKLRDLEDSLA----------RERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEE--GKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLV 513
BLAST of Lamin-B2 vs. Ensembl Human
Match: LMNA (lamin A/C [Source:HGNC Symbol;Acc:HGNC:6636]) HSP 1 Score: 93.9745 bits (232), Expect = 1.654e-19 Identity = 122/526 (23.19%), Postives = 230/526 (43.73%), Query Frame = 1
Query: 91 RKSTNSSLNAS-----------FADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNY----------RKKLEG-YEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEK--------------SILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQD---KLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNIS---------------------GVTTPKRRKINNDDTDDKFQINAYTNDAMKL-FCDEEYNGGHIKLLNDSDKLININEWKLTII-TDDSTSVYCFPDK-NIDSKQTLQIWTVD-----SPVMDDV 1437
R++T S AS +KE++ D LA YID VR++E N L+ E +++ IK+ Y E+ RK LD +A +L LE ++EE L + + L A + + +L+ +++ ++ LEG L+ + + + + K L++E+ + V+ ENR T+ EE+DF K + + +K ET I N + + + ++ L+ Q + E +++LEK Y K + ++ E+ S +R ++L + S L++++ AK+ ++ L + + RE D + + + R + + ++ ++ E +L+D K+AL+ E + + LLEGE+ R +S G + K+RK+ + ++ F +A T+ + + DEE G ++L N S++ ++ W++ DD Y FP K + + Q + IW SP D V
Sbjct: 7 RRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQL-------AAKEAKLRDLEDSLA----------RERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEE--GKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLV 513
BLAST of Lamin-B2 vs. Ensembl Human
Match: LMNA (lamin A/C [Source:HGNC Symbol;Acc:HGNC:6636]) HSP 1 Score: 93.5893 bits (231), Expect = 2.088e-19 Identity = 122/526 (23.19%), Postives = 230/526 (43.73%), Query Frame = 1
Query: 91 RKSTNSSLNAS-----------FADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNY----------RKKLEG-YEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEK--------------SILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQD---KLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNIS---------------------GVTTPKRRKINNDDTDDKFQINAYTNDAMKL-FCDEEYNGGHIKLLNDSDKLININEWKLTII-TDDSTSVYCFPDK-NIDSKQTLQIWTVD-----SPVMDDV 1437
R++T S AS +KE++ D LA YID VR++E N L+ E +++ IK+ Y E+ RK LD +A +L LE ++EE L + + L A + + +L+ +++ ++ LEG L+ + + + + K L++E+ + V+ ENR T+ EE+DF K + + +K ET I N + + + ++ L+ Q + E +++LEK Y K + ++ E+ S +R ++L + S L++++ AK+ ++ L + + RE D + + + R + + ++ ++ E +L+D K+AL+ E + + LLEGE+ R +S G + K+RK+ + ++ F +A T+ + + DEE G ++L N S++ ++ W++ DD Y FP K + + Q + IW SP D V
Sbjct: 7 RRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQL-------AAKEAKLRDLEDSLA----------RERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEE--GKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLV 513
BLAST of Lamin-B2 vs. Ensembl Human
Match: LMNA (lamin A/C [Source:HGNC Symbol;Acc:HGNC:6636]) HSP 1 Score: 93.2041 bits (230), Expect = 2.793e-19 Identity = 122/526 (23.19%), Postives = 230/526 (43.73%), Query Frame = 1
Query: 91 RKSTNSSLNAS-----------FADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNY----------RKKLEG-YEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEK--------------SILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQD---KLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNIS---------------------GVTTPKRRKINNDDTDDKFQINAYTNDAMKL-FCDEEYNGGHIKLLNDSDKLININEWKLTII-TDDSTSVYCFPDK-NIDSKQTLQIWTVD-----SPVMDDV 1437
R++T S AS +KE++ D LA YID VR++E N L+ E +++ IK+ Y E+ RK LD +A +L LE ++EE L + + L A + + +L+ +++ ++ LEG L+ + + + + K L++E+ + V+ ENR T+ EE+DF K + + +K ET I N + + + ++ L+ Q + E +++LEK Y K + ++ E+ S +R ++L + S L++++ AK+ ++ L + + RE D + + + R + + ++ ++ E +L+D K+AL+ E + + LLEGE+ R +S G + K+RK+ + ++ F +A T+ + + DEE G ++L N S++ ++ W++ DD Y FP K + + Q + IW SP D V
Sbjct: 7 RRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQL-------AAKEAKLRDLEDSLA----------RERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEE--GKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLV 513
BLAST of Lamin-B2 vs. Ensembl Human
Match: LMNB1 (lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637]) HSP 1 Score: 76.2554 bits (186), Expect = 7.340e-14 Identity = 118/520 (22.69%), Postives = 218/520 (41.92%), Query Frame = 1
Query: 37 MFNSSPNKENQSRRSIKPRKSTNSSLNASFADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERD-CLSNKLKNETYSLNAMKTDMIELQENISNY----------RKKLEG-YEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKL-----------------NANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRND--NFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISG------------------VTTPKRRKINNDDTDDKFQINAYTNDAMKL-FCDEE--YNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFPDKNI-DSKQTLQIWTVDSPV 1425
M ++P R+ P + + + +KE + D LA YID VR++E N L+ + E +++ +K+ Y E+ R+ALDD A KL +E + E D L N K E+ LN + + E + +++ +K LEG E LK + + + K L +E V+LENR +LTE+++F K + +S E + + Q H + QV + K E+LE+ Y K ++E + N+ E + IE+L + N K+++ A RI + + + L D E ++D++ ++ + L+D K+AL+ E + LLEGE+ R +S T KR++++ ++++ ++ + + C EE +G I+L N S++ + W++ D++ Y + + + + QT+ IW ++ V
Sbjct: 1 MATATPVPPRMGSRAGGPTTPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKCKAEHDQLLLNYAKKES-DLNGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLAAAKKQLADETLLKVDLENRCQSLTEDLEFRKSMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMR-EQHDAQVRLYK-----------EELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESR--ACLERIQELEDLLAKEKDNSRRMLTDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGKRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSVSYKYTSRYVLKAGQTVTIWAANAGV 505
BLAST of Lamin-B2 vs. Ensembl Celegans
Match: ifa-1 (Intermediate filament protein ifa-1 [Source:UniProtKB/Swiss-Prot;Acc:P90901]) HSP 1 Score: 73.9442 bits (180), Expect = 1.431e-13 Identity = 107/475 (22.53%), Postives = 203/475 (42.74%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYS-------LNAMKTDMIELQENISNYRKKLEGYE----VLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTEDFEHCREK-----------LEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCN-------------ISGVTTPKRRKINNDDTDDK--FQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLIN--INEWKLTIITDDSTS-VYCFP-DKNIDSKQTLQIWTVDSPVMDDVDNI 1446
D LA+YI+ VR +EA N L + L + KD + I++ Y E+ +K +D+ + + K +Q+E + KL++ T ++A+ + L+ IS ++++ E +KQE + E + + L E ++ +N+ TL EE+DF ++++ N +Q + D +N E K +L+ RE+ +E +Y K EI + + + E L+ ++ +LR +++ S L +I N +E R ++ L D ++ R ++++ + EL L+D K L+ E ++ +LEGE+ R I+ T + ++ +T + FQ +A N + E G +L ++ + + I EWKL D VY P D + + +TL+I+ + V D +
Sbjct: 78 DRLASYIEKVRFLEAQNRKLAADLDALRSKWGKDTHNIRNMYEGELVDAQKLIDETNKQRKDMEGQLKKMQDELAEMRRKLEDATKGREQDRAKIDALLVTLSNLEAEISLLKRRIAQLEDEVKRIKQENQRLLSELQRARTDLDQETLNRIDYQNQVQTLLEEIDFLRRVHDN-------EIKELQTLASRDTTPENR--EFFKNELSSAIRDIREEYDQVNNVHRNDMESWYRLKVQEIQTQSARQNMEQGYAKEEVKRLRTQLSDLRGKLADLESRNSLLEKQIQELNYQLEDDQRSYEAALNDRDSQIRKMREECQALMVELQMLLDTKQTLDAEIAIYRKMLEGEENRAGLKQLVEQVVKTHAITQETDTETMRVVKGETASRQSFQRSAKGN----VSIHEASPDGKFIVLQNTHRAKDEAIGEWKLKRRIDGKRENVYTLPRDFVLRAGKTLKIFARNQGVASPPDQL 539
BLAST of Lamin-B2 vs. Ensembl Celegans
Match: ifa-1 (Intermediate filament protein ifa-1 [Source:UniProtKB/Swiss-Prot;Acc:P90901]) HSP 1 Score: 73.559 bits (179), Expect = 1.508e-13 Identity = 107/475 (22.53%), Postives = 203/475 (42.74%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYS-------LNAMKTDMIELQENISNYRKKLEGYE----VLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTEDFEHCREK-----------LEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCN-------------ISGVTTPKRRKINNDDTDDK--FQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLIN--INEWKLTIITDDSTS-VYCFP-DKNIDSKQTLQIWTVDSPVMDDVDNI 1446
D LA+YI+ VR +EA N L + L + KD + I++ Y E+ +K +D+ + + K +Q+E + KL++ T ++A+ + L+ IS ++++ E +KQE + E + + L E ++ +N+ TL EE+DF ++++ N +Q + D +N E K +L+ RE+ +E +Y K EI + + + E L+ ++ +LR +++ S L +I N +E R ++ L D ++ R ++++ + EL L+D K L+ E ++ +LEGE+ R I+ T + ++ +T + FQ +A N + E G +L ++ + + I EWKL D VY P D + + +TL+I+ + V D +
Sbjct: 78 DRLASYIEKVRFLEAQNRKLAADLDALRSKWGKDTHNIRNMYEGELVDAQKLIDETNKQRKDMEGQLKKMQDELAEMRRKLEDATKGREQDRAKIDALLVTLSNLEAEISLLKRRIAQLEDEVKRIKQENQRLLSELQRARTDLDQETLNRIDYQNQVQTLLEEIDFLRRVHDN-------EIKELQTLASRDTTPENR--EFFKNELSSAIRDIREEYDQVNNVHRNDMESWYRLKVQEIQTQSARQNMEQGYAKEEVKRLRTQLSDLRGKLADLESRNSLLEKQIQELNYQLEDDQRSYEAALNDRDSQIRKMREECQALMVELQMLLDTKQTLDAEIAIYRKMLEGEENRAGLKQLVEQVVKTHAITQETDTETMRVVKGETASRQSFQRSAKGN----VSIHEASPDGKFIVLQNTHRAKDEAIGEWKLKRRIDGKRENVYTLPRDFVLRAGKTLKIFARNQGVASPPDQL 539
BLAST of Lamin-B2 vs. Ensembl Celegans
Match: ifa-1 (Intermediate filament protein ifa-1 [Source:UniProtKB/Swiss-Prot;Acc:P90901]) HSP 1 Score: 73.559 bits (179), Expect = 1.592e-13 Identity = 107/475 (22.53%), Postives = 204/475 (42.95%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYS-------LNAMKTDMIELQENISNYRKKLEGYE----VLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTEDFEHCREK-----------LEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCN-------------ISGVTTPKRRKINNDDTDDK--FQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLIN--INEWKLTIITDDST-SVYCFP-DKNIDSKQTLQIWTVDSPVMDDVDNI 1446
D LA+YI+ VR +EA N L + L + KD + I++ Y E+ +K +D+ + + K +Q+E + KL++ T ++A+ + L+ IS ++++ E +KQE + E + + L E ++ +N+ TL EE+DF ++++ N +Q + D +N E K +L+ RE+ +E +Y K EI + + + E L+ ++ +LR +++ S L +I N +E R ++ L D ++ R ++++ + EL L+D K L+ E ++ +LEGE+ R I+ T + ++ +T + FQ +A N + E G +L ++ + + I EWKL D +VY P D + + +TL+I+ + V D +
Sbjct: 95 DRLASYIEKVRFLEAQNRKLAADLDALRSKWGKDTHNIRNMYEGELVDAQKLIDETNKQRKDMEGQLKKMQDELAEMRRKLEDATKGREQDRAKIDALLVTLSNLEAEISLLKRRIAQLEDEVKRIKQENQRLLSELQRARTDLDQETLNRIDYQNQVQTLLEEIDFLRRVHDN-------EIKELQTLASRDTTPENR--EFFKNELSSAIRDIREEYDQVNNVHRNDMESWYRLKVQEIQTQSARQNMEQGYAKEEVKRLRTQLSDLRGKLADLESRNSLLEKQIQELNYQLEDDQRSYEAALNDRDSQIRKMREECQALMVELQMLLDTKQTLDAEIAIYRKMLEGEENRAGLKQLVEQVVKTHAITQETDTETMRVVKGETASRQSFQRSAKGN----VSIHEASPDGKFIVLQNTHRAKDEAIGEWKLKRRIDGKRENVYTLPRDFVLRAGKTLKIFARNQGVASPPDQL 556
BLAST of Lamin-B2 vs. Ensembl Celegans
Match: ifa-1 (Intermediate filament protein ifa-1 [Source:UniProtKB/Swiss-Prot;Acc:P90901]) HSP 1 Score: 73.559 bits (179), Expect = 1.665e-13 Identity = 107/475 (22.53%), Postives = 204/475 (42.95%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYS-------LNAMKTDMIELQENISNYRKKLEGYE----VLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTEDFEHCREK-----------LEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCN-------------ISGVTTPKRRKINNDDTDDK--FQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLIN--INEWKLTIITDDST-SVYCFP-DKNIDSKQTLQIWTVDSPVMDDVDNI 1446
D LA+YI+ VR +EA N L + L + KD + I++ Y E+ +K +D+ + + K +Q+E + KL++ T ++A+ + L+ IS ++++ E +KQE + E + + L E ++ +N+ TL EE+DF ++++ N +Q + D +N E K +L+ RE+ +E +Y K EI + + + E L+ ++ +LR +++ S L +I N +E R ++ L D ++ R ++++ + EL L+D K L+ E ++ +LEGE+ R I+ T + ++ +T + FQ +A N + E G +L ++ + + I EWKL D +VY P D + + +TL+I+ + V D +
Sbjct: 70 DRLASYIEKVRFLEAQNRKLAADLDALRSKWGKDTHNIRNMYEGELVDAQKLIDETNKQRKDMEGQLKKMQDELAEMRRKLEDATKGREQDRAKIDALLVTLSNLEAEISLLKRRIAQLEDEVKRIKQENQRLLSELQRARTDLDQETLNRIDYQNQVQTLLEEIDFLRRVHDN-------EIKELQTLASRDTTPENR--EFFKNELSSAIRDIREEYDQVNNVHRNDMESWYRLKVQEIQTQSARQNMEQGYAKEEVKRLRTQLSDLRGKLADLESRNSLLEKQIQELNYQLEDDQRSYEAALNDRDSQIRKMREECQALMVELQMLLDTKQTLDAEIAIYRKMLEGEENRAGLKQLVEQVVKTHAITQETDTETMRVVKGETASRQSFQRSAKGN----VSIHEASPDGKFIVLQNTHRAKDEAIGEWKLKRRIDGKRENVYTLPRDFVLRAGKTLKIFARNQGVASPPDQL 531
BLAST of Lamin-B2 vs. Ensembl Celegans
Match: ifa-1 (Intermediate filament protein ifa-1 [Source:UniProtKB/Swiss-Prot;Acc:P90901]) HSP 1 Score: 73.559 bits (179), Expect = 1.665e-13 Identity = 107/475 (22.53%), Postives = 204/475 (42.95%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYS-------LNAMKTDMIELQENISNYRKKLEGYE----VLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTEDFEHCREK-----------LEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCN-------------ISGVTTPKRRKINNDDTDDK--FQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLIN--INEWKLTIITDDST-SVYCFP-DKNIDSKQTLQIWTVDSPVMDDVDNI 1446
D LA+YI+ VR +EA N L + L + KD + I++ Y E+ +K +D+ + + K +Q+E + KL++ T ++A+ + L+ IS ++++ E +KQE + E + + L E ++ +N+ TL EE+DF ++++ N +Q + D +N E K +L+ RE+ +E +Y K EI + + + E L+ ++ +LR +++ S L +I N +E R ++ L D ++ R ++++ + EL L+D K L+ E ++ +LEGE+ R I+ T + ++ +T + FQ +A N + E G +L ++ + + I EWKL D +VY P D + + +TL+I+ + V D +
Sbjct: 70 DRLASYIEKVRFLEAQNRKLAADLDALRSKWGKDTHNIRNMYEGELVDAQKLIDETNKQRKDMEGQLKKMQDELAEMRRKLEDATKGREQDRAKIDALLVTLSNLEAEISLLKRRIAQLEDEVKRIKQENQRLLSELQRARTDLDQETLNRIDYQNQVQTLLEEIDFLRRVHDN-------EIKELQTLASRDTTPENR--EFFKNELSSAIRDIREEYDQVNNVHRNDMESWYRLKVQEIQTQSARQNMEQGYAKEEVKRLRTQLSDLRGKLADLESRNSLLEKQIQELNYQLEDDQRSYEAALNDRDSQIRKMREECQALMVELQMLLDTKQTLDAEIAIYRKMLEGEENRAGLKQLVEQVVKTHAITQETDTETMRVVKGETASRQSFQRSAKGN----VSIHEASPDGKFIVLQNTHRAKDEAIGEWKLKRRIDGKRENVYTLPRDFVLRAGKTLKIFARNQGVASPPDQL 531
BLAST of Lamin-B2 vs. Ensembl Fly
Match: LamC (gene:FBgn0010397 transcript:FBtr0333166) HSP 1 Score: 97.0561 bits (240), Expect = 9.672e-21 Identity = 121/505 (23.96%), Postives = 215/505 (42.57%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISN-----YRKKLEGYEVLKQEYSDISIENNKNKV-------ALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSI----IQNTHNSDANDKNEQ-VEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKR--------EIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNI--------------------------SGVTTP----------------KRRKINNDDTDDK----FQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFP-DKNIDSKQTLQIWTVDSPVMDDVDN 1443
D LA YID +RN+E N L E ++ ++ +K+ Y +E+ + RK LD+ A KL ++ K L EE D L +L +T + + L EN N Y + L + + + ++++EN + + L+ E V+LEN+ +L EE+ F +++ T + I I + K +Q ++ L+ Q RE++E YDN+ +KA + + L E L R +++NL + N + LN RI ++ + H+ ++ + E + ++D++ ++QE L+D K++L+ E + LL GE+ R NI SG TP KRR+ D+++D+ + +NA +++ + + G IKL N + IN+ W+LT I D + F + ++ IW+VD+ D N
Sbjct: 55 DRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNA-RLYENRYNEVNGKYNQSLADRKKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETRSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQN-LKAAANRAAQGSALATEEVRLMRTKIDGLNAKLQNLEDTN-------AGLNARIRELENLLDTERQRHNQYIASLEAELQRMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGISSNGSHLTASASSRSGRVTPSGRRSATPGISGSSAVKRRRTVIDESEDRTLSEYSVNAAAKGDLEII-EADVEGRFIKLHNKGTEEINLTGWQLTRIAGDEELAFKFSRGSKVLGGASVTIWSVDAGTAHDPPN 549
BLAST of Lamin-B2 vs. Ensembl Fly
Match: LamC (gene:FBgn0010397 transcript:FBtr0087512) HSP 1 Score: 96.2857 bits (238), Expect = 1.296e-20 Identity = 129/540 (23.89%), Postives = 230/540 (42.59%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISN-----YRKKLEGYEVLKQEYSDISIENNKNKV-------ALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSI----IQNTHNSDANDKNEQ-VEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKR--------EIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNI--------------------------SGVTTP----------------KRRKINNDDTDDK----FQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFP-DKNIDSKQTLQIWTVDSPVM-DDVDNIRLNISLPDLSVLRSCTLTNDMDGFEASFKLKRA 1545
D LA YID +RN+E N L E ++ ++ +K+ Y +E+ + RK LD+ A KL ++ K L EE D L +L +T + + L EN N Y + L + + + ++++EN + + L+ E V+LEN+ +L EE+ F +++ T + I I + K +Q ++ L+ Q RE++E YDN+ +KA + + L E L R +++NL + N + LN RI ++ + H+ ++ + E + ++D++ ++QE L+D K++L+ E + LL GE+ R NI SG TP KRR+ D+++D+ + +NA +++ + + G IKL N + IN+ W+LT I D + F + ++ IW+VD+ D +N+ + P + +RS D + AS+ RA
Sbjct: 55 DRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNA-RLYENRYNEVNGKYNQSLADRKKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETRSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQN-LKAAANRAAQGSALATEEVRLMRTKIDGLNAKLQNLEDTN-------AGLNARIRELENLLDTERQRHNQYIASLEAELQRMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGISSNGSHLTASASSRSGRVTPSGRRSATPGISGSSAVKRRRTVIDESEDRTLSEYSVNAAAKGDLEII-EADVEGRFIKLHNKGTEEINLTGWQLTRIAGDEELAFKFSRGSKVLGGASVTIWSVDAGTAHDPPNNLVMKKKWPVANSMRSVLANADKEDV-ASYDRVRA 583
BLAST of Lamin-B2 vs. Ensembl Fly
Match: Lam (gene:FBgn0002525 transcript:FBtr0346460) HSP 1 Score: 86.6557 bits (213), Expect = 1.514e-17 Identity = 124/513 (24.17%), Postives = 229/513 (44.64%), Query Frame = 1
Query: 67 QSRRSIKPRKSTNSSLNASFADKENV-DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETY---------------------SLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDKNEQ-VEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISA-LNNRIVSFNEFIEQRDREHDNHLKDMLNENRI-LQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVT------------------TPKRRKINN---------DDTDDKFQINAYTNDAMKL---FCDEEYNGGHIKLLNDSDKLININEWKLTIITDD--STSVYCFPDK-NIDSKQTLQIWTVDS 1419
S+ + P T S A + +N+ D LA YID VRN+E N L E Q ++ ++ IK+ + E+ R+ LDD A + ++ K L EE + L NKL +T N D +L E+++ K+LE L++++ E KN L+ E V+LEN +L EE+ F ++++ S+ +T +S I +S+ + K +Q ++ L+ Q E + R++++ Y++K + +A ++ + E + + I+ L N N + Q +A LN RI ++ DRE D+L + I L++++ +++E DL+D K++L+ E + LL GE+ R NI+ T TP RR + D+++D + Y + + K + + G ++L N + + I W+L + ++ ++ Y F I+ + +W+ D+
Sbjct: 36 HSQTASSPLSPTRHSRVAEKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNEDLNEALKELER---LRKQFE----ETRKN---LEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAARTSNSTHKSIEELRSTRVRIDAL-NANINELEQANADLNARIRDLERQLDN-DRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITPATNTATVQSFSQSLRNSTRATPSRRTPSAAVKRKRAVVDESEDHSVADYYVSASAKGNVEIKEIDPEGKFVRLFNKGSEEVAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWSADT 536
BLAST of Lamin-B2 vs. Ensembl Fly
Match: Lam (gene:FBgn0002525 transcript:FBtr0307059) HSP 1 Score: 86.6557 bits (213), Expect = 1.514e-17 Identity = 124/513 (24.17%), Postives = 229/513 (44.64%), Query Frame = 1
Query: 67 QSRRSIKPRKSTNSSLNASFADKENV-DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETY---------------------SLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDKNEQ-VEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISA-LNNRIVSFNEFIEQRDREHDNHLKDMLNENRI-LQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVT------------------TPKRRKINN---------DDTDDKFQINAYTNDAMKL---FCDEEYNGGHIKLLNDSDKLININEWKLTIITDD--STSVYCFPDK-NIDSKQTLQIWTVDS 1419
S+ + P T S A + +N+ D LA YID VRN+E N L E Q ++ ++ IK+ + E+ R+ LDD A + ++ K L EE + L NKL +T N D +L E+++ K+LE L++++ E KN L+ E V+LEN +L EE+ F ++++ S+ +T +S I +S+ + K +Q ++ L+ Q E + R++++ Y++K + +A ++ + E + + I+ L N N + Q +A LN RI ++ DRE D+L + I L++++ +++E DL+D K++L+ E + LL GE+ R NI+ T TP RR + D+++D + Y + + K + + G ++L N + + I W+L + ++ ++ Y F I+ + +W+ D+
Sbjct: 36 HSQTASSPLSPTRHSRVAEKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNEDLNEALKELER---LRKQFE----ETRKN---LEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAARTSNSTHKSIEELRSTRVRIDAL-NANINELEQANADLNARIRDLERQLDN-DRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITPATNTATVQSFSQSLRNSTRATPSRRTPSAAVKRKRAVVDESEDHSVADYYVSASAKGNVEIKEIDPEGKFVRLFNKGSEEVAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWSADT 536
BLAST of Lamin-B2 vs. Ensembl Fly
Match: Lam (gene:FBgn0002525 transcript:FBtr0307058) HSP 1 Score: 86.6557 bits (213), Expect = 1.514e-17 Identity = 124/513 (24.17%), Postives = 229/513 (44.64%), Query Frame = 1
Query: 67 QSRRSIKPRKSTNSSLNASFADKENV-DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETY---------------------SLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDKNEQ-VEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISA-LNNRIVSFNEFIEQRDREHDNHLKDMLNENRI-LQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVT------------------TPKRRKINN---------DDTDDKFQINAYTNDAMKL---FCDEEYNGGHIKLLNDSDKLININEWKLTIITDD--STSVYCFPDK-NIDSKQTLQIWTVDS 1419
S+ + P T S A + +N+ D LA YID VRN+E N L E Q ++ ++ IK+ + E+ R+ LDD A + ++ K L EE + L NKL +T N D +L E+++ K+LE L++++ E KN L+ E V+LEN +L EE+ F ++++ S+ +T +S I +S+ + K +Q ++ L+ Q E + R++++ Y++K + +A ++ + E + + I+ L N N + Q +A LN RI ++ DRE D+L + I L++++ +++E DL+D K++L+ E + LL GE+ R NI+ T TP RR + D+++D + Y + + K + + G ++L N + + I W+L + ++ ++ Y F I+ + +W+ D+
Sbjct: 36 HSQTASSPLSPTRHSRVAEKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNEDLNEALKELER---LRKQFE----ETRKN---LEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAARTSNSTHKSIEELRSTRVRIDAL-NANINELEQANADLNARIRDLERQLDN-DRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITPATNTATVQSFSQSLRNSTRATPSRRTPSAAVKRKRAVVDESEDHSVADYYVSASAKGNVEIKEIDPEGKFVRLFNKGSEEVAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWSADT 536
BLAST of Lamin-B2 vs. Ensembl Zebrafish
Match: lmna (lamin A [Source:ZFIN;Acc:ZDB-GENE-020424-3]) HSP 1 Score: 90.1225 bits (222), Expect = 1.789e-18 Identity = 118/491 (24.03%), Postives = 212/491 (43.18%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQE-------NISNYRKKLEGYEV----LKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVS----FNEFIEQRDREHD---NHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNIS-------GVTT------------------------PKRRKINNDDTD---------DKFQINAYTNDAMKLFCDE-EYNGGHIKLLNDSDKLININEWKL-TIITDDSTSVYCFPDK-NIDSKQTLQIWTVDS 1419
D LA YID VR++E N L+ +++ +K+ Y E+ RK LD +A +L LE ++E+ L + + L + + +L+ ++S + EV LK + + + N K L++E+ + V+ ENR TL EE++F K + + SK E+ I + D K + + L+ Q E +E++EK Y++K + E R + L G E++ R +Q+S L ++ + E E RE D L+D E ++ ++ ++ E +L+D K+AL+ E + LLEGE+ R +S GVT K+R++N++D+D + +I+ + + ++ DE + G ++L N SD+ ++ W++ I + VY FP K N+ + QT+ IW +
Sbjct: 37 DRLAVYIDKVRSLEVENAGLRMRITESETEISRELSGMKAAYEAELADARKTLDSVAKERARLQLELSKVREDYKELKARNGKKEADLESALARLKDLESLLNSKDASLSTALGEKRTLEVEVRDLKAQLAKLEGSLNDAKKQLQDEMLRRVDAENRIQTLKEELEFQKNIYSEELRESKRRYESRVVEIDSGRQQDYESKLADALTDLRNQHEEQLRIYKEEIEKTYNSKLENARSSAE----RNSHLVGAAHE---ELQQTRVRMEGVSSQLSQLQKQLAAREAKIRELEEALSRERDILRRRLEDKEKEMAEMRQRMQQQLDEYQELLDIKLALDMEISAYRKLLEGEEERLRLSPSPPPARGVTVTRSSGSGSHTRVVQSSTSRTSSGSAKKRRLNDNDSDASSVVGGTVTRTRISQQASASGRVTVDEVDLEGKFVRLNNKSDQDQSLGHWQVKRQIGSGTPIVYKFPPKFNLKAGQTVTIWAAGA 520
BLAST of Lamin-B2 vs. Ensembl Zebrafish
Match: lmna (lamin A [Source:ZFIN;Acc:ZDB-GENE-020424-3]) HSP 1 Score: 90.1225 bits (222), Expect = 1.789e-18 Identity = 118/491 (24.03%), Postives = 212/491 (43.18%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQE-------NISNYRKKLEGYEV----LKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVS----FNEFIEQRDREHD---NHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNIS-------GVTT------------------------PKRRKINNDDTD---------DKFQINAYTNDAMKLFCDE-EYNGGHIKLLNDSDKLININEWKL-TIITDDSTSVYCFPDK-NIDSKQTLQIWTVDS 1419
D LA YID VR++E N L+ +++ +K+ Y E+ RK LD +A +L LE ++E+ L + + L + + +L+ ++S + EV LK + + + N K L++E+ + V+ ENR TL EE++F K + + SK E+ I + D K + + L+ Q E +E++EK Y++K + E R + L G E++ R +Q+S L ++ + E E RE D L+D E ++ ++ ++ E +L+D K+AL+ E + LLEGE+ R +S GVT K+R++N++D+D + +I+ + + ++ DE + G ++L N SD+ ++ W++ I + VY FP K N+ + QT+ IW +
Sbjct: 37 DRLAVYIDKVRSLEVENAGLRMRITESETEISRELSGMKAAYEAELADARKTLDSVAKERARLQLELSKVREDYKELKARNGKKEADLESALARLKDLESLLNSKDASLSTALGEKRTLEVEVRDLKAQLAKLEGSLNDAKKQLQDEMLRRVDAENRIQTLKEELEFQKNIYSEELRESKRRYESRVVEIDSGRQQDYESKLADALTDLRNQHEEQLRIYKEEIEKTYNSKLENARSSAE----RNSHLVGAAHE---ELQQTRVRMEGVSSQLSQLQKQLAAREAKIRELEEALSRERDILRRRLEDKEKEMAEMRQRMQQQLDEYQELLDIKLALDMEISAYRKLLEGEEERLRLSPSPPPARGVTVTRSSGSGSHTRVVQSSTSRTSSGSAKKRRLNDNDSDASSVVGGTVTRTRISQQASASGRVTVDEVDLEGKFVRLNNKSDQDQSLGHWQVKRQIGSGTPIVYKFPPKFNLKAGQTVTIWAAGA 520
BLAST of Lamin-B2 vs. Ensembl Zebrafish
Match: lmna (lamin A [Source:ZFIN;Acc:ZDB-GENE-020424-3]) HSP 1 Score: 90.1225 bits (222), Expect = 1.789e-18 Identity = 118/491 (24.03%), Postives = 212/491 (43.18%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQE-------NISNYRKKLEGYEV----LKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVS----FNEFIEQRDREHD---NHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNIS-------GVTT------------------------PKRRKINNDDTD---------DKFQINAYTNDAMKLFCDE-EYNGGHIKLLNDSDKLININEWKL-TIITDDSTSVYCFPDK-NIDSKQTLQIWTVDS 1419
D LA YID VR++E N L+ +++ +K+ Y E+ RK LD +A +L LE ++E+ L + + L + + +L+ ++S + EV LK + + + N K L++E+ + V+ ENR TL EE++F K + + SK E+ I + D K + + L+ Q E +E++EK Y++K + E R + L G E++ R +Q+S L ++ + E E RE D L+D E ++ ++ ++ E +L+D K+AL+ E + LLEGE+ R +S GVT K+R++N++D+D + +I+ + + ++ DE + G ++L N SD+ ++ W++ I + VY FP K N+ + QT+ IW +
Sbjct: 37 DRLAVYIDKVRSLEVENAGLRMRITESETEISRELSGMKAAYEAELADARKTLDSVAKERARLQLELSKVREDYKELKARNGKKEADLESALARLKDLESLLNSKDASLSTALGEKRTLEVEVRDLKAQLAKLEGSLNDAKKQLQDEMLRRVDAENRIQTLKEELEFQKNIYSEELRESKRRYESRVVEIDSGRQQDYESKLADALTDLRNQHEEQLRIYKEEIEKTYNSKLENARSSAE----RNSHLVGAAHE---ELQQTRVRMEGVSSQLSQLQKQLAAREAKIRELEEALSRERDILRRRLEDKEKEMAEMRQRMQQQLDEYQELLDIKLALDMEISAYRKLLEGEEERLRLSPSPPPARGVTVTRSSGSGSHTRVVQSSTSRTSSGSAKKRRLNDNDSDASSVVGGTVTRTRISQQASASGRVTVDEVDLEGKFVRLNNKSDQDQSLGHWQVKRQIGSGTPIVYKFPPKFNLKAGQTVTIWAAGA 520
BLAST of Lamin-B2 vs. Ensembl Zebrafish
Match: lmna (lamin A [Source:ZFIN;Acc:ZDB-GENE-020424-3]) HSP 1 Score: 90.1225 bits (222), Expect = 2.170e-18 Identity = 118/491 (24.03%), Postives = 212/491 (43.18%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQE-------NISNYRKKLEGYEV----LKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVS----FNEFIEQRDREHD---NHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNIS-------GVTT------------------------PKRRKINNDDTD---------DKFQINAYTNDAMKLFCDE-EYNGGHIKLLNDSDKLININEWKL-TIITDDSTSVYCFPDK-NIDSKQTLQIWTVDS 1419
D LA YID VR++E N L+ +++ +K+ Y E+ RK LD +A +L LE ++E+ L + + L + + +L+ ++S + EV LK + + + N K L++E+ + V+ ENR TL EE++F K + + SK E+ I + D K + + L+ Q E +E++EK Y++K + E R + L G E++ R +Q+S L ++ + E E RE D L+D E ++ ++ ++ E +L+D K+AL+ E + LLEGE+ R +S GVT K+R++N++D+D + +I+ + + ++ DE + G ++L N SD+ ++ W++ I + VY FP K N+ + QT+ IW +
Sbjct: 37 DRLAVYIDKVRSLEVENAGLRMRITESETEISRELSGMKAAYEAELADARKTLDSVAKERARLQLELSKVREDYKELKARNGKKEADLESALARLKDLESLLNSKDASLSTALGEKRTLEVEVRDLKAQLAKLEGSLNDAKKQLQDEMLRRVDAENRIQTLKEELEFQKNIYSEELRESKRRYESRVVEIDSGRQQDYESKLADALTDLRNQHEEQLRIYKEEIEKTYNSKLENARSSAE----RNSHLVGAAHE---ELQQTRVRMEGVSSQLSQLQKQLAAREAKIRELEEALSRERDILRRRLEDKEKEMAEMRQRMQQQLDEYQELLDIKLALDMEISAYRKLLEGEEERLRLSPSPPPARGVTVTRSSGSGSHTRVVQSSTSRTSSGSAKKRRLNDNDSDASSVVGGTVTRTRISQQASASGRVTVDEVDLEGKFVRLNNKSDQDQSLGHWQVKRQIGSGTPIVYKFPPKFNLKAGQTVTIWAAGA 520
BLAST of Lamin-B2 vs. Ensembl Zebrafish
Match: lmnl3 (lamin L3 [Source:ZFIN;Acc:ZDB-GENE-020424-4]) HSP 1 Score: 88.1965 bits (217), Expect = 7.617e-18 Identity = 124/520 (23.85%), Postives = 231/520 (44.42%), Query Frame = 1
Query: 31 LIMFNSSPNKENQSRRSIKPRKSTNSSLNAS------FADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLS--------------NKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSIIQNTHNS-----DANDKNE----QVEILKRQLTEDFE----HCREKLEKFYDNKC-NEIMKANEKSILRYNT---LFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCN---------ISGVTTPKRRKINNDDTDDKF----QINAYTNDAMKLFCDE-EYNGGHIKLLNDSDKLININEWKLTIITDDSTS-VYCFPDKNI-DSKQTLQIWTVDS 1419
+ M S+P + + S R+S S S +KE++ D LANYI+ VR +EA +++ + ES +++ ++ Y E+ RK+LD A +L +E LQE+ L+ ++ +N +LNA + D L +S R+ LK + + K K L +E+ + V+ EN+ TL E++DF K L E +++ H S D + E E +K QL ++ E +++LEK ++ K N A + S ++T L G + L+ E + + +N K Q+ L R++ + +E + L E L+ ++ +++E +L+D K+ L+ E + +LEGE+ R N +S + R+K +D T F +++ +++ + +E + +G +IKL N SD+ ++ W+L ++ V+CFP + ++ L +W +
Sbjct: 1 MAMVTSTPMERSASAAVRASRRSGASPCTVSPTRLTRLQEKEDLRQLNDRLANYIERVRQLEADKSSMQILLEEKEESSLREVGNVRRLYESELADARKSLDATANERARLQIEFSQLQEDHRKLAARNNKKECELTAAVDRWRNLEVALNAKEADFANL---LSTNRRLETEISELKTQVPALEAALQKLKTQLNSEMLRRVDAENQIQTLQEQLDFQKHLG-------EQEVREMRSRHESRLLELDCGRQKEFEGKLAEAMK-QLRDEHETQIRQYKDELEKTFNAKLENAKQTAVKNSDFAFSTKEELAG--TKLRLESQTQQINNLQK--QVVCLEARVLELQQTLEHERQVSQQKLSQQQQEMAALRLQMQEQLEEYENLLDVKLMLDMEINAYRKMLEGEEKRLNQSLSPIQQTLSPIIQQSRKKRKHDATCSGFSPNYRLSQHSSCRGPVSIEEVDLDGRYIKLKNASDRDQVVSGWQLRKSEAEAPDIVFCFPSPCVMNAGHMLTVWAAAA 505
BLAST of Lamin-B2 vs. Ensembl Xenopus
Match: timm13 (translocase of inner mitochondrial membrane 13 homolog [Source:NCBI gene;Acc:734099]) HSP 1 Score: 90.5077 bits (223), Expect = 1.870e-18 Identity = 123/511 (24.07%), Postives = 233/511 (45.60%), Query Frame = 1
Query: 37 MFNSSPNKENQSRRSIKPRKSTNSSLNAS----FADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEV-----LKQEYSDISIENNKN-------KVALKNEICKCVELENRRITLTEEVDF----YKKLNANSKITTETSFSIIQNTHNSDANDKNEQ-VEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQ-RDREH---DNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKRR--------KINNDDTDDKFQINAYTNDAMKLFCDEEYN--GGHIKLLNDSDKLININEWKLTI-ITDDSTSVYCF-PDKNIDSKQTLQIWTVDSPVMDDVDNI 1446
M ++P++ S P + T++ L+ + +KE + D LA YID VR++E N+ L + E +++ IK+ Y E+ RK LD+ A +L +E + + D L+ K + L+ + + +L+ +L G + L+ E +D+ + +K K L+ E V+ ENR +L EE+DF Y++ + ++ E + H D + K Q ++ L++Q E + +E+LE+ Y K + I ++++ + NT E + + IE L Q +A +RI + + RD+ D+ K+M ++D++ ++ E +L+D K+AL+ E + LLEGE+ R +S +P+ R ++ + + N A EE + G ++ L N+SDK ++ W+L I ++ VY F P + + Q+++I++ D+ V +I
Sbjct: 1 MATATPSRSGTSSMQ-SPARGTSTPLSPTRISRLQEKEELRHLNDRLAVYIDRVRSLELENDRLMVKISEKEEVTTREVSGIKNLYESELADARKVLDETARERARLQIELGKFRSDLDELTKNYKKKDADLSTAQGRIRDLEALFHRSEAEL-GTALGEKRSLEAEVADLRAQLSKAEDAHAVAKKQLEKETLMRVDFENRIQSLQEEMDFRKNIYEEESRETRKRHERRIVEVDRGHQCDYDSKLAQALDELRKQHDEQVKMYKEELEQTYQAKLDNIKRSSDHNDKAANTAREELTEARMRIETLSYQLSGLQKQANAAEDRIRELEQLLSSDRDKYRKLLDSKEKEMAE----MRDQMQQQLTEYQELLDVKLALDMEINAYRKLLEGEEERLKLS--PSPQSRVTVSRATSSSSSATRTSRSKRNRTVTSATGSISIEEIDLEGKYVHLKNNSDKDQSLGNWRLKRKIGEEEEIVYKFTPKYVLKAGQSVKIYSADAGVAHSPPSI 503
BLAST of Lamin-B2 vs. Ensembl Xenopus
Match: timm13 (translocase of inner mitochondrial membrane 13 homolog [Source:NCBI gene;Acc:734099]) HSP 1 Score: 89.3521 bits (220), Expect = 4.379e-18 Identity = 124/514 (24.12%), Postives = 233/514 (45.33%), Query Frame = 1
Query: 37 MFNSSPNKENQSRRSIKPRKSTNSSLNAS----FADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEV-----LKQEYSDISIENNKN-------KVALKNEICKCVELENRRITLTEEVDF----YKKLNANSKITTETSFSIIQNTHNSDANDKNEQ-VEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQ-RDREH---DNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKRR-----------KINNDDTDDKFQINAYTNDAMKLFCDEEYN--GGHIKLLNDSDKLININEWKLTI-ITDDSTSVYCF-PDKNIDSKQTLQIWTVDSPVMDDVDNI 1446
M ++P++ S P + T++ L+ + +KE + D LA YID VR++E N+ L + E +++ IK+ Y E+ RK LD+ A +L +E + + D L+ K + L+ + + +L+ +L G + L+ E +D+ + +K K L+ E V+ ENR +L EE+DF Y++ + ++ E + H D + K Q ++ L++Q E + +E+LE+ Y K + I ++++ + NT E + + IE L Q +A +RI + + RD+ D+ K+M ++D++ ++ E +L+D K+AL+ E + LLEGE+ R +S +P+ R + I A ++A EE + G ++ L N+SDK ++ W+L I ++ VY F P + + Q+++I++ D+ V +I
Sbjct: 1 MATATPSRSGTSSMQ-SPARGTSTPLSPTRISRLQEKEELRHLNDRLAVYIDRVRSLELENDRLMVKISEKEEVTTREVSGIKNLYESELADARKVLDETARERARLQIELGKFRSDLDELTKNYKKKDADLSTAQGRIRDLEALFHRSEAEL-GTALGEKRSLEAEVADLRAQLSKAEDAHAVAKKQLEKETLMRVDFENRIQSLQEEMDFRKNIYEEESRETRKRHERRIVEVDRGHQCDYDSKLAQALDELRKQHDEQVKMYKEELEQTYQAKLDNIKRSSDHNDKAANTAREELTEARMRIETLSYQLSGLQKQANAAEDRIRELEQLLSSDRDKYRKLLDSKEKEMAE----MRDQMQQQLTEYQELLDVKLALDMEINAYRKLLEGEEERLKLS--PSPQSRVTVSRATSSSSSATRTSRSKRNHITA--SEATGSISIEEIDLEGKYVHLKNNSDKDQSLGNWRLKRKIGEEEEIVYKFTPKYVLKAGQSVKIYSADAGVAHSPPSI 504
BLAST of Lamin-B2 vs. Ensembl Xenopus
Match: timm13 (translocase of inner mitochondrial membrane 13 homolog [Source:NCBI gene;Acc:734099]) HSP 1 Score: 88.5817 bits (218), Expect = 7.011e-18 Identity = 122/520 (23.46%), Postives = 235/520 (45.19%), Query Frame = 1
Query: 37 MFNSSPNKENQSRRSIKPRKSTNSSLNAS----FADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEV-----LKQEYSDISIENNKN-------KVALKNEICKCVELENRRITLTEEVDF----YKKLNANSKITTETSFSIIQNTHNSDANDKNEQ-VEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQ-RDREH---DNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKRRKINNDDTDD------------------KFQINAYTNDAMKLFCDE-EYNGGHIKLLNDSDKLININEWKLTI-ITDDSTSVYCF-PDKNIDSKQTLQIWTVDSPVMDDVDNI 1446
M ++P++ S P + T++ L+ + +KE + D LA YID VR++E N+ L + E +++ IK+ Y E+ RK LD+ A +L +E + + D L+ K + L+ + + +L+ +L G + L+ E +D+ + +K K L+ E V+ ENR +L EE+DF Y++ + ++ E + H D + K Q ++ L++Q E + +E+LE+ Y K + I ++++ + NT E + + IE L Q +A +RI + + RD+ D+ K+M ++D++ ++ E +L+D K+AL+ E + LLEGE+ R +S +P+ R + T +F ++ + + +E + G ++ L N+SDK ++ W+L I ++ VY F P + + Q+++I++ D+ V +I
Sbjct: 1 MATATPSRSGTSSMQ-SPARGTSTPLSPTRISRLQEKEELRHLNDRLAVYIDRVRSLELENDRLMVKISEKEEVTTREVSGIKNLYESELADARKVLDETARERARLQIELGKFRSDLDELTKNYKKKDADLSTAQGRIRDLEALFHRSEAEL-GTALGEKRSLEAEVADLRAQLSKAEDAHAVAKKQLEKETLMRVDFENRIQSLQEEMDFRKNIYEEESRETRKRHERRIVEVDRGHQCDYDSKLAQALDELRKQHDEQVKMYKEELEQTYQAKLDNIKRSSDHNDKAANTAREELTEARMRIETLSYQLSGLQKQANAAEDRIRELEQLLSSDRDKYRKLLDSKEKEMAE----MRDQMQQQLTEYQELLDVKLALDMEINAYRKLLEGEEERLKLS--PSPQSRVTVSRATSSSSSATRTSRSKRKRTGFTRFHLSQQASATGSISIEEIDLEGKYVHLKNNSDKDQSLGNWRLKRKIGEEEEIVYKFTPKYVLKAGQSVKIYSADAGVAHSPPSI 512
BLAST of Lamin-B2 vs. Ensembl Xenopus
Match: timm13 (translocase of inner mitochondrial membrane 13 homolog [Source:NCBI gene;Acc:734099]) HSP 1 Score: 88.5817 bits (218), Expect = 7.288e-18 Identity = 118/509 (23.18%), Postives = 228/509 (44.79%), Query Frame = 1
Query: 88 PRKSTNSSLNAS----FADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEV-----LKQEYSDISIENNKN-------KVALKNEICKCVELENRRITLTEEVDF----YKKLNANSKITTETSFSIIQNTHNSDANDKNEQ-VEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQ-RDREH---DNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKRR------------------------KINNDDTDDKFQINAYTNDAMKLFCDE-EYNGGHIKLLNDSDKLININEWKLTI-ITDDSTSVYCF-PDKNIDSKQTLQIWTVDSPVMDDVDNI 1446
P + T++ L+ + +KE + D LA YID VR++E N+ L + E +++ IK+ Y E+ RK LD+ A +L +E + + D L+ K + L+ + + +L+ +L G + L+ E +D+ + +K K L+ E V+ ENR +L EE+DF Y++ + ++ E + H D + K Q ++ L++Q E + +E+LE+ Y K + I ++++ + NT E + + IE L Q +A +RI + + RD+ D+ K+M ++D++ ++ E +L+D K+AL+ E + LLEGE+ R +S +P+ R + + +F ++ + + +E + G ++ L N+SDK ++ W+L I ++ VY F P + + Q+++I++ D+ V +I
Sbjct: 4 PARGTSTPLSPTRISRLQEKEELRHLNDRLAVYIDRVRSLELENDRLMVKISEKEEVTTREVSGIKNLYESELADARKVLDETARERARLQIELGKFRSDLDELTKNYKKKDADLSTAQGRIRDLEALFHRSEAEL-GTALGEKRSLEAEVADLRAQLSKAEDAHAVAKKQLEKETLMRVDFENRIQSLQEEMDFRKNIYEEESRETRKRHERRIVEVDRGHQCDYDSKLAQALDELRKQHDEQVKMYKEELEQTYQAKLDNIKRSSDHNDKAANTAREELTEARMRIETLSYQLSGLQKQANAAEDRIRELEQLLSSDRDKYRKLLDSKEKEMAE----MRDQMQQQLTEYQELLDVKLALDMEINAYRKLLEGEEERLKLS--PSPQSRVTVSRATSSSSSATRTSRSKRNRTVTSGQGSSTRFHLSQQASATGSISIEEIDLEGKYVHLKNNSDKDQSLGNWRLKRKIGEEEEIVYKFTPKYVLKAGQSVKIYSADAGVAHSPPSI 505
BLAST of Lamin-B2 vs. Ensembl Xenopus
Match: timm13 (translocase of inner mitochondrial membrane 13 homolog [Source:NCBI gene;Acc:734099]) HSP 1 Score: 84.7297 bits (208), Expect = 1.116e-16 Identity = 120/520 (23.08%), Postives = 231/520 (44.42%), Query Frame = 1
Query: 88 PRKSTNSSLNAS----FADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEV-----LKQEYSDISIENNKN-------KVALKNEICKCVELENRRITLTEEVDF----YKKLNANSKITTETSFSIIQNTHNSDANDKNEQ-VEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQ-RDREH---DNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISG-----VTTP---------------KRRKI---------------NNDDTDDKFQINAYTNDAMKLFCDE-EYNGGHIKLLNDSDKLININEWKLTI-ITDDSTSVYCF-PDKNIDSKQTLQIWTVDSPVMDDVDNI 1446
P + T++ L+ + +KE + D LA YID VR++E N+ L + E +++ IK+ Y E+ RK LD+ A +L +E + + D L+ K + L+ + + +L+ +L G + L+ E +D+ + +K K L+ E V+ ENR +L EE+DF Y++ + ++ E + H D + K Q ++ L++Q E + +E+LE+ Y K + I ++++ + NT E + + IE L Q +A +RI + + RD+ D+ K+M ++D++ ++ E +L+D K+AL+ E + LLEGE+ R +S VT KR+++ + + +F ++ + + +E + G ++ L N+SDK ++ W+L I ++ VY F P + + Q+++I++ D+ V +I
Sbjct: 15 PARGTSTPLSPTRISRLQEKEELRHLNDRLAVYIDRVRSLELENDRLMVKISEKEEVTTREVSGIKNLYESELADARKVLDETARERARLQIELGKFRSDLDELTKNYKKKDADLSTAQGRIRDLEALFHRSEAEL-GTALGEKRSLEAEVADLRAQLSKAEDAHAVAKKQLEKETLMRVDFENRIQSLQEEMDFRKNIYEEESRETRKRHERRIVEVDRGHQCDYDSKLAQALDELRKQHDEQVKMYKEELEQTYQAKLDNIKRSSDHNDKAANTAREELTEARMRIETLSYQLSGLQKQANAAEDRIRELEQLLSSDRDKYRKLLDSKEKEMAE----MRDQMQQQLTEYQELLDVKLALDMEINAYRKLLEGEEERLKLSPSPQSRVTVSRATSSSSSATRTSRSKRKRVEEEYEEGGGSSRTVTSGQGSSTRFHLSQQASATGSISIEEIDLEGKYVHLKNNSDKDQSLGNWRLKRKIGEEEEIVYKFTPKYVLKAGQSVKIYSADAGVAHSPPSI 529
BLAST of Lamin-B2 vs. Ensembl Mouse
Match: Lmna (lamin A [Source:MGI Symbol;Acc:MGI:96794]) HSP 1 Score: 87.4261 bits (215), Expect = 1.268e-17 Identity = 123/526 (23.38%), Postives = 229/526 (43.54%), Query Frame = 1
Query: 91 RKSTNSSLNAS-----------FADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNY----------RKKLEG-YEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEK--------------SILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQD---KLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKR---------------------RKINNDDTDDKFQINAYTNDAMKL-FCDEEYNGGHIKLLNDSDKLININEWKLTII-TDDSTSVYCFPDK-NIDSKQTLQIW-----TVDSPVMDDV 1437
R++T S AS +KE++ D LA YID VR++E N L+ E +++ IK+ Y E+ RK LD +A +L LE ++EE L + + L A + + +L+ +++ ++ LEG L+ + + + + K L++E+ + V+ ENR TL EE+DF K + + +K ET I N + + + ++ L+ Q + E +++LEK Y K + ++ E+ S +R ++L + S L++++ AK+ ++ L + + RE D + + + R + + ++ ++ E +L+D K+AL+ E + + LLEGE+ R +S T +R RK+ + ++ F +A T+ + + DEE G ++L N S++ ++ W++ DD Y FP K + + Q + IW SP D V
Sbjct: 7 RRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQL-------AAKEAKLRDLEDSLA----------RERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQSQGGGSVTKKRKLESSESRSSFSQHARTSGRVAVEEVDEE--GKFVRLRNKSNEDQSMGNWQIRRQNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLV 513
BLAST of Lamin-B2 vs. Ensembl Mouse
Match: Lmna (lamin A [Source:MGI Symbol;Acc:MGI:96794]) HSP 1 Score: 87.4261 bits (215), Expect = 1.631e-17 Identity = 122/516 (23.64%), Postives = 229/516 (44.38%), Query Frame = 1
Query: 91 RKSTNSSLNAS-----------FADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNY----------RKKLEG-YEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVS----FNEFIEQRDREHDNHLKDMLNENRILQD---KLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKR---------------------RKINNDDTDDKFQINAYTNDAMKL-FCDEEYNGGHIKLLNDSDKLININEWKLTII-TDDSTSVYCFPDK-NIDSKQTLQIW-----TVDSPVMDDV 1437
R++T S AS +KE++ D LA YID VR++E N L+ E +++ IK+ Y E+ RK LD +A +L LE ++EE L + + L A + + +L+ +++ ++ LEG L+ + + + + K L++E+ + V+ ENR TL EE+DF K + + +K ET I N + + + ++ L+ Q + E +++LEK Y K + ++ E++ N + + L++ +R D+ + Q+S L ++ + + + RE D + + + R + + ++ ++ E +L+D K+AL+ E + + LLEGE+ R +S T +R RK+ + ++ F +A T+ + + DEE G ++L N S++ ++ W++ DD Y FP K + + Q + IW SP D V
Sbjct: 7 RRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERN---SNLVGAAHEELQQS--RIRIDSLSA--QLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQSQGGGSVTKKRKLESSESRSSFSQHARTSGRVAVEEVDEE--GKFVRLRNKSNEDQSMGNWQIRRQNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLV 513
BLAST of Lamin-B2 vs. Ensembl Mouse
Match: Lmnb1 (lamin B1 [Source:MGI Symbol;Acc:MGI:96795]) HSP 1 Score: 73.1738 bits (178), Expect = 3.673e-13 Identity = 119/524 (22.71%), Postives = 224/524 (42.75%), Query Frame = 1
Query: 37 MFNSSP-NKENQSRRSIKPRKSTNSSLNASFADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERD-CLSNKLKNETYSLNAMKTDMIELQENISNY----------RKKLEG-YEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKL-----------------NANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRND--NFAKDNQISALNNRIVSFNEFIEQRDREHDNH---LKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISG------------------VTTPKRRKINNDDTDDKFQINAYTNDAMKL-FCDEE--YNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFPDKNI-DSKQTLQIWTVDSPV 1425
M ++P ++ R+ P + + + +KE + D LA YID VR++E N L+ + E +++ +K+ Y E+ R+ALDD A KL +E + E D L N K E+ L+ + + E + +++ +K LEG E LK + + + + K L +E V+LENR +LTE+++F K + +S E + + Q H + QV + K E+LE+ Y K ++E + N+ E + IE+L + N K+++ A RI + + +E DN L D E ++D++ ++ + L+D K+AL+ E + LLEGE+ R +S T KR++++ ++++ ++ + + C EE +G I+L N S++ + W++ D++ Y + + + + QT+ +W ++ V
Sbjct: 1 MATATPVQQQRAGSRASAPATPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKES-DLSGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMR-EQHDAQVRLYK-----------EELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESR--ACLERIQELEDMLA---KERDNSRRMLSDREREMAEIRDQMQQQLSDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGKRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSVSYKYTSRYVLKAGQTVTVWAANAGV 506
BLAST of Lamin-B2 vs. Ensembl Mouse
Match: Lmnb2 (lamin B2 [Source:MGI Symbol;Acc:MGI:96796]) HSP 1 Score: 65.4698 bits (158), Expect = 1.191e-10 Identity = 111/525 (21.14%), Postives = 207/525 (39.43%), Query Frame = 1
Query: 49 SPNKENQSRRSIKPRKSTNSSLNAS----FADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKL-------EGYEV----LKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKL----NANSKITTETSFSIIQNTHNSDANDKNEQ-VEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIE-QRDREHDNHLKDMLN----ENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTP--------------------------KRRKINNDDTDDKFQINAYTNDAMKLF----------CDE-EYNGGHIKLLNDSDKLININEWKL--TIITDDSTSVYCFPDKNIDSKQTLQIWTVDS 1419
SP + S+ P + L+ + +KE + D LA+YID VR +E N+ L E +++ IK+ Y E+ R+ LD+ A +L +E +Q E + K L + + +L+ +L +G E L+ + + + K L+ E V+LENR +L EE+ F K + ++ E + ++ + + K Q +E L+ Q E R +LE+ Y K + ++++ + E + +E+L Q SA N I E + +RD+ + ML+ E ++D + ++ E +L+D K+AL+ E + LLEGE+ R +S + KRR++ +DT + + +L DE + G ++L N SDK ++ W++ ++ + + P + + QT+ +W +
Sbjct: 12 SPAAATSAMASLPPHAGPATPLSPTRLSRLQEKEELRELNDRLAHYIDRVRALELENDRLLLRISEKEEVTTREVSGIKTLYESELADARRVLDETARERARLQIEIGKVQAELEEARKSAKKREGELTVAQGRVKDLESLFHRSEAELATALSDKQGLETEVAELRAQLAKAEDGHAVAKKQLEKETLMRVDLENRCQSLQEELAFSKSVFEEEVRETRRRHERRLVEVDSSRQQEYDFKMAQALEDLRSQHDEQVRLYRVELEQTYQAKLDNAKLLSDQNDKAAHAAREELKEARMRVESLSYQLLGLQKQASAAENHIHELEEALAGERDK-----FRKMLDAKEQEMTEVRDAMQQQLAEYQELLDIKLALDMEISAYRKLLEGEEERLKLSPSPSSRITISRATSSSSSSSGVGMSVGQGRGKRRRLETEDTSGSPSRASRVSSGSRLAQQTVATGVVNIDEVDPEGRFVRLKNSSDKDQSLGNWRIKRQVLEGEDIAYKFTPKYVLRAGQTVTVWAAGA 531
BLAST of Lamin-B2 vs. Ensembl Mouse
Match: Lmnb2 (lamin B2 [Source:MGI Symbol;Acc:MGI:96796]) HSP 1 Score: 63.1586 bits (152), Expect = 5.414e-10 Identity = 109/515 (21.17%), Postives = 204/515 (39.61%), Query Frame = 1
Query: 79 SIKPRKSTNSSLNAS----FADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKL-------EGYEV----LKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKL----NANSKITTETSFSIIQNTHNSDANDKNEQ-VEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIE-QRDREHDNHLKDMLN----ENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTP--------------------------KRRKINNDDTDDKFQINAYTNDAMKLF----------CDE-EYNGGHIKLLNDSDKLININEWKL--TIITDDSTSVYCFPDKNIDSKQTLQIWTVDS 1419
S+ P + L+ + +KE + D LA+YID VR +E N+ L E +++ IK+ Y E+ R+ LD+ A +L +E +Q E + K L + + +L+ +L +G E L+ + + + K L+ E V+LENR +L EE+ F K + ++ E + ++ + + K Q +E L+ Q E R +LE+ Y K + ++++ + E + +E+L Q SA N I E + +RD+ + ML+ E ++D + ++ E +L+D K+AL+ E + LLEGE+ R +S + KRR++ +DT + + +L DE + G ++L N SDK ++ W++ ++ + + P + + QT+ +W +
Sbjct: 3 SLPPHAGPATPLSPTRLSRLQEKEELRELNDRLAHYIDRVRALELENDRLLLRISEKEEVTTREVSGIKTLYESELADARRVLDETARERARLQIEIGKVQAELEEARKSAKKREGELTVAQGRVKDLESLFHRSEAELATALSDKQGLETEVAELRAQLAKAEDGHAVAKKQLEKETLMRVDLENRCQSLQEELAFSKSVFEEEVRETRRRHERRLVEVDSSRQQEYDFKMAQALEDLRSQHDEQVRLYRVELEQTYQAKLDNAKLLSDQNDKAAHAAREELKEARMRVESLSYQLLGLQKQASAAENHIHELEEALAGERDK-----FRKMLDAKEQEMTEVRDAMQQQLAEYQELLDIKLALDMEISAYRKLLEGEEERLKLSPSPSSRITISRATSSSSSSSGVGMSVGQGRGKRRRLETEDTSGSPSRASRVSSGSRLAQQTVATGVVNIDEVDPEGRFVRLKNSSDKDQSLGNWRIKRQVLEGEDIAYKFTPKYVLRAGQTVTVWAAGA 512
BLAST of Lamin-B2 vs. UniProt/SwissProt
Match: sp|Q03427|LAMC_DROME (Lamin-C OS=Drosophila melanogaster OX=7227 GN=LamC PE=1 SV=2) HSP 1 Score: 96.2857 bits (238), Expect = 1.299e-19 Identity = 129/540 (23.89%), Postives = 230/540 (42.59%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISN-----YRKKLEGYEVLKQEYSDISIENNKNKV-------ALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSI----IQNTHNSDANDKNEQ-VEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKR--------EIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNI--------------------------SGVTTP----------------KRRKINNDDTDDK----FQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFP-DKNIDSKQTLQIWTVDSPVM-DDVDNIRLNISLPDLSVLRSCTLTNDMDGFEASFKLKRA 1545
D LA YID +RN+E N L E ++ ++ +K+ Y +E+ + RK LD+ A KL ++ K L EE D L +L +T + + L EN N Y + L + + + ++++EN + + L+ E V+LEN+ +L EE+ F +++ T + I I + K +Q ++ L+ Q RE++E YDN+ +KA + + L E L R +++NL + N + LN RI ++ + H+ ++ + E + ++D++ ++QE L+D K++L+ E + LL GE+ R NI SG TP KRR+ D+++D+ + +NA +++ + + G IKL N + IN+ W+LT I D + F + ++ IW+VD+ D +N+ + P + +RS D + AS+ RA
Sbjct: 55 DRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNA-RLYENRYNEVNGKYNQSLADRKKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETRSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQN-LKAAANRAAQGSALATEEVRLMRTKIDGLNAKLQNLEDTN-------AGLNARIRELENLLDTERQRHNQYIASLEAELQRMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGISSNGSHLTASASSRSGRVTPSGRRSATPGISGSSAVKRRRTVIDESEDRTLSEYSVNAAAKGDLEII-EADVEGRFIKLHNKGTEEINLTGWQLTRIAGDEELAFKFSRGSKVLGGASVTIWSVDAGTAHDPPNNLVMKKKWPVANSMRSVLANADKEDV-ASYDRVRA 583
BLAST of Lamin-B2 vs. UniProt/SwissProt
Match: sp|P02545|LMNA_HUMAN (Prelamin-A/C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1) HSP 1 Score: 93.9745 bits (232), Expect = 7.945e-19 Identity = 122/526 (23.19%), Postives = 230/526 (43.73%), Query Frame = 1
Query: 91 RKSTNSSLNAS-----------FADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNY----------RKKLEG-YEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEK--------------SILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQD---KLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNIS---------------------GVTTPKRRKINNDDTDDKFQINAYTNDAMKL-FCDEEYNGGHIKLLNDSDKLININEWKLTII-TDDSTSVYCFPDK-NIDSKQTLQIWTVD-----SPVMDDV 1437
R++T S AS +KE++ D LA YID VR++E N L+ E +++ IK+ Y E+ RK LD +A +L LE ++EE L + + L A + + +L+ +++ ++ LEG L+ + + + + K L++E+ + V+ ENR T+ EE+DF K + + +K ET I N + + + ++ L+ Q + E +++LEK Y K + ++ E+ S +R ++L + S L++++ AK+ ++ L + + RE D + + + R + + ++ ++ E +L+D K+AL+ E + + LLEGE+ R +S G + K+RK+ + ++ F +A T+ + + DEE G ++L N S++ ++ W++ DD Y FP K + + Q + IW SP D V
Sbjct: 7 RRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQL-------AAKEAKLRDLEDSLA----------RERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEE--GKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLV 513
BLAST of Lamin-B2 vs. UniProt/SwissProt
Match: sp|Q3ZD69|LMNA_PIG (Prelamin-A/C OS=Sus scrofa OX=9823 GN=LMNA PE=3 SV=1) HSP 1 Score: 91.2781 bits (225), Expect = 7.045e-18 Identity = 124/526 (23.57%), Postives = 220/526 (41.83%), Query Frame = 1
Query: 91 RKSTNSSLNAS-----------FADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNY----------RKKLEG-YEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEK--------------SILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNH---LKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKRRKINNDDTDDKFQINAYTNDAMKLF----------------------CDEEYNGGHIKLLNDSDKLININEWKLTII-TDDSTSVYCFPDK-NIDSKQTLQIWTVD-----SPVMDDV 1437
R++T S AS +KE++ D LA YID VR++E N L+ E +++ IKS Y E+ RK LD +A +L LE ++EE L + + L A + + +L+ +++ ++ LEG L+ + + + + K L++E+ + V+ ENR TL EE+DF K + + +K ET I N + + + ++ L+ Q + E +++LEK Y K + ++ E+ S +R ++L + S L++++ AK+ ++ L + + RE D L D E ++ ++ ++ E +L+D K+AL+ E + + LLEGE+ R +S T +R + + Q KL DEE G ++L N S++ ++ W++ DD Y FP K + + Q + IW SP D V
Sbjct: 7 RRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKSAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLMAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQDLRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQL-------AAKEAKLRDLEDSLA----------RERDTSRRLLADKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQSGGSVTKKRKLESSESRSSFSQHARTSGRVAVEEVDEE--GKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPADLV 513
BLAST of Lamin-B2 vs. UniProt/SwissProt
Match: sp|P13648|LMNA_CHICK (Lamin-A OS=Gallus gallus OX=9031 GN=LMNA PE=2 SV=1) HSP 1 Score: 89.7373 bits (221), Expect = 1.946e-17 Identity = 115/479 (24.01%), Postives = 209/479 (43.63%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGY---------EV--LKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNH-LKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNI-----------------SGVTTPKRRKINNDDTDDK------FQINAYTNDAMKLFCDE-EYNGGHIKLLNDSDKLININEWKLTII-TDDSTSVYCFPDK-NIDSKQTLQIW-----TVDSPVMDDV 1437
D LA YID VR++E N L+ E +++ IK+ Y E+ RK LD +A +L LE ++EE L + + L A + + +L+ +++ L EV L+ + + + ++ K L++E+ + V+ ENR TL EE++F K + + +K ET I N + K E ++ L+RQ + H R++LEK Y K ++ E++ E I++L + Q++A ++ E + R+RE L + E ++ ++ ++ E +L+D K+AL+ E + LLEGE+ R + SG + K+R++ + + + F +A T+ ++ +E + G ++L N S++ + W++ DD Y FP K + + Q + IW SP D V
Sbjct: 39 DRLAVYIDKVRSLELENAGLRLRITESEEVVSREVSGIKAAYEAELADARKTLDSVAKERARLQLELSKVREEHKELKARNAKKEADLLAAQARLKDLEALLNSKEAALSTALGEKRNLENEVRDLRAQVAKLEGALSEAKKQLQDEMLRRVDAENRLQTLKEELEFQKNIYSEELRETKRRHETRLVEIDNGRQQEFESKLAEALQDLRRQHEDQIRHYRDELEKTYGAKLENAKQSAERNSSMAGAAHEELQQTHIRIDSLSAELSQLQKQLAAKEAKLREVEEAL-SREREGGRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEINAYRKLLEGEEERLRLSPSPSSQRGARSSGLQHSGAGSAKKRRLEDGEGREGREGRTSFSHHARTSG--RVGVEEVDLEGRFVRLRNKSNEDQALGNWQVKRQNGDDPPLTYRFPPKFTLKAGQAVTIWASGAGATHSPPSDVV 514
BLAST of Lamin-B2 vs. UniProt/SwissProt
Match: sp|P48678|LMNA_MOUSE (Prelamin-A/C OS=Mus musculus OX=10090 GN=Lmna PE=1 SV=2) HSP 1 Score: 87.4261 bits (215), Expect = 1.141e-16 Identity = 122/516 (23.64%), Postives = 229/516 (44.38%), Query Frame = 1
Query: 91 RKSTNSSLNAS-----------FADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNY----------RKKLEG-YEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVS----FNEFIEQRDREHDNHLKDMLNENRILQD---KLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKR---------------------RKINNDDTDDKFQINAYTNDAMKL-FCDEEYNGGHIKLLNDSDKLININEWKLTII-TDDSTSVYCFPDK-NIDSKQTLQIW-----TVDSPVMDDV 1437
R++T S AS +KE++ D LA YID VR++E N L+ E +++ IK+ Y E+ RK LD +A +L LE ++EE L + + L A + + +L+ +++ ++ LEG L+ + + + + K L++E+ + V+ ENR TL EE+DF K + + +K ET I N + + + ++ L+ Q + E +++LEK Y K + ++ E++ N + + L++ +R D+ + Q+S L ++ + + + RE D + + + R + + ++ ++ E +L+D K+AL+ E + + LLEGE+ R +S T +R RK+ + ++ F +A T+ + + DEE G ++L N S++ ++ W++ DD Y FP K + + Q + IW SP D V
Sbjct: 7 RRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERN---SNLVGAAHEELQQS--RIRIDSLSA--QLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQSQGGGSVTKKRKLESSESRSSFSQHARTSGRVAVEEVDEE--GKFVRLRNKSNEDQSMGNWQIRRQNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLV 513
BLAST of Lamin-B2 vs. TrEMBL
Match: A0A0X3NM60 (Lamin-B2 OS=Schistocephalus solidus OX=70667 GN=LMNB2 PE=3 SV=1) HSP 1 Score: 129.798 bits (325), Expect = 4.333e-28 Identity = 119/481 (24.74%), Postives = 228/481 (47.40%), Query Frame = 1
Query: 79 SIKPRKSTNSSLNASFAD-KENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKL--NANSKITTETSFSIIQNTHNSDANDKNEQV--EIL--KRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVT-------TPKRRKINNDDTDD---------------KFQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFPDK-NIDSKQTLQIWTVDS 1419
S + R+ + S LN + +D KE + D LA+YIDYVR +E E +K + Q++ E + + TY +EI SLR+ +DDLA ++E K +++ NKL ++ + L+ ++S ++ E Y+ LK E+ + + L+ E +LEN+ L EE+DF +L K+ + T +I + + A + ++ E+L ++Q ++ + R ++E + K +E+ AN + L E +++ ++L ++ K ++ LN R+ + Q + +N L+ E + LQD+L L+ E +DL++ KIAL++E ++ +LEGE++R NI K+R+++ D D+ F+++ ++ +++ G +KL+N SD+ +++ W L D + F + T IW+ D+
Sbjct: 43 SPRRRERSVSPLNITRSDEKEELASLNDRLAHYIDYVRKLEKDKETMKRKIQSITEERISRVDEARRTYEDEIASLRQLVDDLAKQKAVTDMELKKHRDDAADAKNKLARRDLEARGLQRKVDALEHDLSAFKDDHERYQRLKPEFDTLEKRLEAMRRDLEAETILRTDLENKVAGLREELDFKNRLFDEERQKLVSRT-LTIEEEIEDRKAAEYESRLADELLSFRQQTGDELQEYRCQMENTFQKKLDELRAANSNASDESLRLRDEIIVVRKRADDLTHELAKKTGEVDLLNRRLSDLEHQLNQEREDFENQLRAQRAEVKRLQDELELRFGEFTDLMNTKIALDQEILMYRKMLEGEESRLNIQSPQRDSAFYLAGKKRRLDADYDDETSSSEMPETSSTARYSFRVSTSATGGVEFSSEQDGQGRWVKLVNSSDEDVSLGNWVLKHQADGRECSFKFHRSVTLKPSATCTIWSSDA 522
BLAST of Lamin-B2 vs. TrEMBL
Match: A0A3P7LLR0 (Uncharacterized protein OS=Dibothriocephalus latus OX=60516 GN=DILT_LOCUS7664 PE=3 SV=1) HSP 1 Score: 127.487 bits (319), Expect = 2.414e-27 Identity = 123/490 (25.10%), Postives = 231/490 (47.14%), Query Frame = 1
Query: 70 SRRSIKP---RKSTNSSLNASFAD-KENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKL--NANSKITTETSFSIIQNTHNSDANDKNEQV--EIL--KRQLTEDFEHCREKLEKFY---DNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVT-------TPKRRKINNDDTDD---------------KFQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFPDK-NIDSKQTLQIWTVDS 1419
SR S P R+ + S LN + +D KE + D LA YIDYVR +E E +K + Q++ E + +STY +EI SLR +DDLA ++E K +++ NKL ++ + L+ ++S +R E Y+ LK EY ++ + L+ E +LEN+ L EE+DF +L K+ + T +I + + A + ++ E+L ++Q ++ + R ++E + K +E+ AN + L E +++ ++L ++ K ++ LN R+ + + + + L++ E + LQD+L + E +DL++ KIAL++E ++ +LEGE++R NI + + K+R+++ D D+ F+++ ++ +++ G +KL+N SD+ I++ W L D + F + T IW+ D+
Sbjct: 37 SRESFTPSRRRERSVSPLNITRSDEKEELASLNDRLAQYIDYVRKLEKDKETMKRKMQSITEERISRVDEARSTYEDEIASLRALVDDLAKQKAATDMELKKHRDDAADAKNKLARRDLEARGLQRKIDALEHDLSAFRDDHECYQRLKPEYDNLEKRLEAMRRDLEAETILRTDLENKVAGLREELDFKNRLFDEERQKLVSRT-LTIEEEIEDRKAAEYESRLADELLSFRQQTGDELQVYRTQMENTFQATQKKLDELRAANSNASDESVRLRDEIVVVRKRADDLTHELAKKSGEVDLLNRRLSDLERMLRLQREDFEAQLQEKRAEVKRLQDELEQRFGEFTDLMNTKIALDQEILMYRKMLEGEESRLNIQSPSRDSAFHLSSKKRRLDVDYDDETSSSELPETSSTARYSFRVSTSATGGVEFSSEQDGQGRWVKLVNSSDEEISLGNWVLKHQADGRDCSFKFHRSVTLKPAVTCTIWSSDA 525
BLAST of Lamin-B2 vs. TrEMBL
Match: A0A564ZD22 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS14838 PE=3 SV=1) HSP 1 Score: 125.946 bits (315), Expect = 7.994e-27 Identity = 140/563 (24.87%), Postives = 266/563 (47.25%), Query Frame = 1
Query: 46 SSPNKENQSR-RSIKPRKSTNSSLNASFAD-KENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKL--NANSKITTETSFSIIQNTHNSDAND----KNEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNEN---RILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNIS----------GVTTPKRRKINNDDTDDK----------FQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFPDKNIDSKQ-TL-QIWTVDSPVMDDV--DNIRLNISLPDLSVLRSCTLTNDMDGFEASFKLKRAEPRKILKAHPR--NVQTNERCAIM 1611
SSP + +++ RS P LN S D KE + D LA+YIDYVR +E E+L + E + + TY EI SLR+ +DDLA ++E K ++ +KL L ++ L+ +I Y+ E Y+ L E+ D+ K LK E +LEN+ +L EE+DF +L SK+ T ++ + + A + ++++ + E+ E R ++E + NK ++ KANE++ L E + ++R ++L ++ K ++ L+ RI + + ++ HD++ + E + L+ +L + E +DL++ K+ L++E ++ +LEGE++R N++ G + K+R++++ D D+ +++ + +++ D++ +G +KL N + IN+ W L +D Y F +N+ K TL +W+ D+ + D + N S + + + TLTND + +AS + R K++ R +++E+C++M
Sbjct: 35 SSPAQPSEAEYRSPSP-------LNISRVDEKEELAHLNDRLASYIDYVRKLERDKESLTRRISTITEERLAKVDDARKTYENEIQSLRRLVDDLAKEKAARDVELKKHIDDASDAKSKLNKRDAELRNLQRKYDTLERDIGAYKADHERYQKLLPEFEDLEKNLEAAKEGLKAETILRTDLENKVASLREELDFKDRLFQEERSKLVMHT-LTVEEEVAETKAMEFESRLADELQAYRDSANEELEQYRFQMESTFQNKLEQLQKANEEANRDGGRLTEELTIMRRMNDDLSHELARKSREVELLHGRIADLEKLL---NKTHDDYQAQLAAEREEIKRLRSELEQRFAEFTDLMNTKVVLDQEILMYRKMLEGEESRLNLTSPKRHSAFSGGFMSAKKRRLDSGDGFDEESGSSGSQTAIRVSTSSVGSIEFSADQDGSGKWVKLGNVGKEDINLGNWVLKHKSDGEEVTYKFA-RNVTLKPGTLCTLWSSDAGATHNPPEDIVMKNQSFHTGANI-TVTLTNDNEEEQASCLIVRESRPKLISRRFRAGATKSDEKCSLM 584
BLAST of Lamin-B2 vs. TrEMBL
Match: A0A158QIY6 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS10512 PE=3 SV=1) HSP 1 Score: 127.102 bits (318), Expect = 9.032e-27 Identity = 128/505 (25.35%), Postives = 228/505 (45.15%), Query Frame = 1
Query: 43 NSSPNKENQSRRSIKPRKSTNSSLNASFADKENVDGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKL--NANSKITTETSF--SIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKAN-----EKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNIS----GVTTPKRRK------INNDDTDD--------------------KFQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFPDKNI-DSKQTLQIWTVDSPVMDD 1434
++S + E +RS+ P + + A E D LA+YIDYVR +EA ++LK + + E ++TY EI SLR+ +DDLA ++E + L+++ +KL ++ + L+ +IS Y+ + YE LK EY + + + L E +LEN+ L EE+ F +L +KI +T S I++ ++ K +Q++ + Q ED + ++E ++NK N++ AN E S LR L ++ ++ ++ KD ++ L R+ Q +++ L +E LQ +L ++ E +DL++ K+AL++E ++ +LEGE++R NIS G +T +R+ I +D D +++ + ++ D+ G +KL+N SD+ NI W L D + FP I + QIW D+ +D
Sbjct: 610 SASSSAEGHRQRSVSPLNISRTEEKEELA--ELNDRLASYIDYVRKLEADKDSLKRKIRTFTEERMSKHDDSRNTYESEIASLRRLVDDLAKQKAAADVEAEKLKDDAKTAQSKLAKRELDARNLQRRVEALERDISAYKHDHDRYEALKPEYDALEKKCTDLRRDLDAETVHRSDLENKVAGLKEELKFKNRLLDEERAKIIEKTIMVESEIEDRKAAEYESKLYDQLQSYRDQTAEDLLTYKIEMEHTFENKLNQLRAANTDASKETSRLRDQLLI-----YRKRTDDAEHELKKKDAELELLKRRVDELERLRRQEREDYERSLAAQRDELARLQRELEIRFSEFTDLMNTKVALDQEILMYRKMLEGEESRLNISTSLRGPSTGSKRRRPTSAVIEEEDDDGIHSTSTSSLISGGEGRFPRVTYRVATNSTSNIEFAADQGELGKCVKLVNTSDEDTNIGNWTLKQTVDGHGVTFKFPRSLILKPGASCQIWNSDAGATND 1107 HSP 2 Score: 122.865 bits (307), Expect = 2.533e-25 Identity = 121/474 (25.53%), Postives = 220/474 (46.41%), Query Frame = 1
Query: 106 SSLNASFAD-KENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKL--NANSKITTETSFSIIQNTHNSDAND----KNEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKR-------------RKINNDDTDDK----------FQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFPDKNIDSKQTLQ--IWTVDS 1419
S LN S D KE + D LA+YIDYVR +E E+L + E + + +STY EI SLR+ +DDLA ++E K ++ +KL L ++ L+ +I Y+ E Y+ L E+ + K LK E +LEN+ +L EE+DF +L SK+ S ++ + + A + ++++ + E+ E R ++E + K ++ KANE++ L E ++R ++L ++ K ++ L++RI + + + ++ L E + L+ +L + E +DL++ KI L++E ++ +LEGE++R N+ T+PKR R++++ D D+ +++ +++ D++ +G IKL N + INI W L +D Y F +N+ K +W+VD+
Sbjct: 49 SPLNISRVDEKEELAHLNDRLASYIDYVRKLERDKESLTRRISTITEERLAKVDSARSTYENEIQSLRRLVDDLAKDKAARDVELKKHMDDASDAKSKLNKRDAELRNLQRKYDALERDIGTYKADHERYQKLLPEFEHLEKNLEAAKEGLKAETILRTDLENKVASLREELDFKDRLFQEERSKLVMR-SLTVEEEVAETKAKEFESRLADELQAYRESANEELEQYRIQMESTFQKKLEQLQKANEEANRDGGRLNEELITMRRMNDDLSHELARKSREVELLHSRIADLEKLLNKAHDDYQAQLAAEREEVKRLRAELEQRFAEFTDLMNTKIVLDQEILMYRKMLEGEESRLNL---TSPKRHSAFGGAFMGVKKRRLDSGDGFDEESNSNGSQTAIRVSTSAVGSIEFSADQDSSGNWIKLSNVGKEDINIGNWVLRHKSDGEEVTYKF-GRNVTLKPGTPCIVWSVDA 517
BLAST of Lamin-B2 vs. TrEMBL
Match: A0A0R3X3R8 (Uncharacterized protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS7990 PE=3 SV=2) HSP 1 Score: 126.716 bits (317), Expect = 1.601e-26 Identity = 122/500 (24.40%), Postives = 237/500 (47.40%), Query Frame = 1
Query: 46 SSPNKENQSRRSIKPRKS--------TNSSLNASFAD-KENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKL--NANSKITTETSFSIIQNTHNSDAND----KNEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGV--TTP--------KRRKIN-NDDTDD---------KFQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFPDK-NIDSKQTLQIWTVDSPV 1425
S+P K + SR + S ++S L S D KE + D LA+YIDYVR +E E L + E + + TY +EI SLR+ +DDLA +E K ++ + KL + +++ + L+ +++ Y++ + Y+ L+ EY ++ + + L+ E +LEN+ +L EE+DF +L SK+ T ++ + + A + ++++ ++Q ++ + R ++E + K ++ +AN ++ L E ++R ++L ++ K ++ L NR+ + + ++ L +E + L+ +L + E +DL++ KIAL++E ++ +LEGE++R N++ T+P KRR+++ D+ DD F+++ ++ D++ +G IKL+N + + INI W L D VY F ++ T +W+ DS V
Sbjct: 19 STPKKADHSRATSSTGTSASECTEHRSSSPLAISRVDEKEELAHLNDRLASYIDYVRKLERDKECLTRRISTISEERLSQVDEARKTYEKEIASLRRLVDDLAKEKAAKEVELKKHIDDMNDAKAKLCKRDAEVRSLQLKVDTLERDVAMYKQDYDRYQQLRPEYDEVEKKLEATRKGLEAETVLRTDLENKVASLREELDFKDRLFQEERSKLVMRT-LTVEEEVEDRKAAEFESRLADELQAYRQQTNDELQQYRIQMETTFQTKLEQLQQANAEANKDSGRLNDELLVMRRRCDDLCHELAKKTREVDLLQNRVHDLESLLNKAHDDYQAQLAAERDEIKRLKAELEQRFAEFTDLMNTKIALDQEILMYRKMLEGEESRLNLTSPKRTSPFSGTYMGVKRRRLDSGDELDDDSSSCGSQFAFRVSTSAVGDIEFTADQDGSGKWIKLINVAKQDINIGNWALKHQADGEEVVYKFGRAFSLKPGATCTVWSSDSGV 517 HSP 2 Score: 111.694 bits (278), Expect = 1.029e-21 Identity = 128/523 (24.47%), Postives = 240/523 (45.89%), Query Frame = 1
Query: 43 NSSPNKENQSRRSIKPRKSTNSSLNASFADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYT----IKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNANSKIT----TETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDML---NENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTP----------KRRKINNDDTDDK------------------------FQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKL--------ININEWKLTIITDDSTSVYCFPDKNI-DSKQTLQIWTVDSPVMDD 1434
+S+P+ + + +RS+ P N S N +KE + D LA+YIDYVR +E E+LK + I++Y ++ + ++TY EI SLR+ +DDLA +E + +++ +KL + ++ + L+ +++ Y++ + YE LK +Y + + L E +LEN+ L EE++F +L ++ T T S I++ ++ K +Q++ + Q ED + ++E ++NK N++ AN + + L E +++ ++L ++ K ++ L R+ +E R E D++ K + E LQ +L + E +DL++ K+AL++E ++ +LEGE+TR NI V+ P +RR +N D +++ +++ +N ++ D+ G +K++N SD+ NI W L D + FP I + QIW DS +D
Sbjct: 603 SSAPSGDRRRQRSVSP---LNISRNE---EKEELAELNDRLASYIDYVRKLEMDKEHLKRK----IKTYSEERLSKHDDARNTYEAEIASLRRLVDDLAKQKAVAEVEAEKHKDDAKTAQSKLGKRESEVRGLQRRVEGLERDLTAYKQDHDRYEALKPDYDALEKRCTALRRDLDAETVLRNDLENKLAGLREELNFKNRLLEEERLKAVERTITVESEIEDRKAAEYESKLYDQLQAYRDQTAEDLLAYKTEMEHTFENKLNQLRAANSDASKETDRLRDELLVVRKRSDDLEHELGKKVAEVDLLKRRV---DELERMRRHERDDYEKRLALQREELARLQRELEIHFAEFADLMNTKVALDQEILMYRKMLEGEETRLNIP-VSGPREGPVAAGAKRRRPLNVDYDEEEGEEEDEGIHSTSTSSLGSSMPRVTYRVATNSNGNIEFAPDQNEMGKCVKIVNSSDEACQNGLGTETNIGNWVLKQKADSHEVTFKFPRSLILQPGASCQIWNSDSGATND 1111
BLAST of Lamin-B2 vs. Ensembl Cavefish
Match: lmna (lamin A [Source:ZFIN;Acc:ZDB-GENE-020424-3]) HSP 1 Score: 87.4261 bits (215), Expect = 9.750e-18 Identity = 113/459 (24.62%), Postives = 208/459 (45.32%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNY----------RKKLEGYEV--LKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLN----ANSKITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVS----FNEFIEQRDREHDNHLKDMLNENRILQD---KLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKR-RKINNDDTD---------DKFQINAYTNDAMKLFCDE-EYNGGHIKLLNDSDKLININEWKLTIITDDSTS-VYCFPDK-NIDSKQTLQIWT 1410
D LA YID VR++EA N L+ +++ +K+ Y E+ RK LD +A +L LE ++E+ L + + L A + +L+ +++ ++ LE EV LK + + + N K L++E+ + V+ ENR TL EE++F K + SK E+ I + + K + + L+ Q E +E++EK Y+ K ++ +S R + L G E++ R + Q+S L ++ + E E RE D + + R + D ++ ++ E +L+D K+AL+ E + LLEGE+ R +S P R R++N+ D++ + +I + + ++ DE + G ++L N +D+ ++ W++ ST +Y FP K + + Q++ IW
Sbjct: 37 DRLAVYIDKVRSLEAENAGLRLRITESETEISREMGGMKAAYETELADARKTLDSVAKERARLQLELSKVREDYKELKARNSKKEADLEAALARLKDLEALLNSKDASLTTALGEKRSLE-VEVRDLKAQLAKLEGSLNDAKKQLQDEMLRRVDAENRIQTLKEELEFQKNIYNEELRESKRRHESRIVEIDSGKQQEFESKLADALTELRGQHEEQLRIYKEEIEKTYNAK----LENARQSADRNSHLVGAAHE---ELQQTRVRLESMSAQLSQLQKQLAAREAKVRELEEALSRERDMMRRRLDEREREMSDMRQRMQQQLDEYQELLDIKLALDMEISAYRKLLEGEEERLRLSPSPPPTRKRRLNDTDSEASSVAGGMVTRTRITQQASASGRITVDEVDLEGKFVRLSNKADQDQSLGHWQVKRQVGTSTPIIYKFPPKFTLKAGQSVTIWA 487
BLAST of Lamin-B2 vs. Ensembl Cavefish
Match: lmnb1 (lamin B1 [Source:NCBI gene;Acc:103034386]) HSP 1 Score: 75.485 bits (184), Expect = 6.109e-14 Identity = 117/526 (22.24%), Postives = 219/526 (41.63%), Query Frame = 1
Query: 46 SSPNKENQSRRSIKPRKSTNSSLNASFADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCL--------------SNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEV-LKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKL-----------------NANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEK---SILRYNTLFGENSNLKREIENLRNDNFAKDN-----QISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISG------------------VTTPKRRKINNDDTDDKFQIN-AYTNDAMKLFCDEE--YNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCF-PDKNIDSKQTLQIWTVDSPV 1425
S+P S + P + T +KE + D LA YID VR++E+ N L + E +++ +K+ Y E+ R++LDD A +L +E ++ E + L +LK+ LN+ + + + RK LEG L+ + ++ + L +E V+LENR +L EE++F K + +S E F + Q + ++QV++ K ++ + + E + + + A E+ + LR +L + S L++E E N ++ Q +RI + Q L D E ++ K+ L+++E L+D K+AL+ E + LLEGE+ R +S T KR++++ ++++ ++ A++ A C +E +G I+L N SD+ + +++T DS++ Y F P + + Q + IW ++ V
Sbjct: 6 STPAGRRMSSTPLSPTRITR------LQEKEELSNLNDRLAIYIDKVRSLESENSVLHLQISEKEEVRSRELTGLKALYETELADARRSLDDTAKERARLQIELGKIRTEHEQLLQSYAKKDSDLAGCQARLKDVEALLNSKEASLA----TALSERKALEGSLADLQAQIHELEASLASARKQLGDETLLRVDLENRCQSLVEELEFRKNMFEEEIKDTRRRHETRLVEVDSGRQVEYEFKLAQALTDMR-QQHDDQVKVYKEEMEQTYMAKLENVRLSSEMNSSSASMAREELKEASLRVESLTAQLSGLQKEEEETLNRGSSRGGGECQDQARGWQDRINELESALAQEKDLSRRMLADKEREISEIRAKMQLQLEEYEQLLDVKLALDMEINAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGKRKRVDVEESEASSSVSIAHSASATGNVCIDELDVDGKFIRLHNTSDQDQPMVGFEMTRTIGDSSATYKFTPKYVLKAGQKVTIWASNAGV 520
BLAST of Lamin-B2 vs. Ensembl Cavefish
Match: lmnb2 (lamin B2 [Source:NCBI gene;Acc:103025469]) HSP 1 Score: 74.3294 bits (181), Expect = 1.577e-13 Identity = 115/515 (22.33%), Postives = 215/515 (41.75%), Query Frame = 1
Query: 37 MFNSSPNKENQSRRSIKPRKSTNSSLNASFADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGY----EVLKQEYSDISIENNKNKVA-------LKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSIIQNTHNSDANDK-----NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKA---NEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRIL---QDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKRR-------------KINNDDTDDKFQINAYTNDAMKLFCDEEYNGG-----------HIKLLNDSDKLININEWKLT-IITDDSTSVYCF-PDKNIDSKQTLQIWTVDSPV 1425
M ++P++E+ S P T S +KE + D LA YID VR +E N+ L + E +++ IKS Y E+ R+ +D++A +L ++ E + ++ K + L + + EL+ + L L E +D+ + K + A L+ E V+LENR +LTEE+ F K + T +S A ++ ++ L++Q E +E+LE+ + K + + N+K++ +T E IE+L A Q +A +R+ + + + E D + + M + R + ++++ +++ E +L+D K+AL+ E + LLEGE+ R +S +P R + + + T ++++ E GG + L N++DK ++ W+L I + VY F P + + QT+ +W D+ V
Sbjct: 1 MATATPSRESGRAASSTPLSPTRIS---RLQEKEELRHLNDRLAVYIDRVRALELENDRLMVKVSEKEEVTTREVSGIKSLYEAELADARRVVDEIAKERARLQIDLGKSNSELEEITKSFKKKDGDLVLAQARIKELESQYNQSEAALNTALSENAALSAELADVKTQLAKAEDAHAVAKKQLEAETLMRVDLENRCQSLTEELQFRKSMFEEEVRETRRRREKRMVEVDSGAKQDYEFKLSQALQDLRKQHEEQVGFYKEELEQTFQAKLDNAKVSSDLNDKAV---STAREELQEAHVRIESLSYQLSALQKQAAAAEDRVRELEDIL---NSERDKYRRMMDGKEREMSEMRERMQMQLNEYQELLDVKLALDMEINAYRKLLEGEEDRLKLS--PSPSSRVTVSRSTASSSSSRTTRSTKRKRVEEEPVTAPSVRISQQAEATGGVTVEEIDLEGKSVTLKNNADKDQSLGSWRLKRQIGEADEIVYKFSPKFVLKAGQTVTVWAADAGV 504
BLAST of Lamin-B2 vs. Ensembl Cavefish
Match: lmnb1 (lamin B1 [Source:NCBI gene;Acc:103034386]) HSP 1 Score: 69.3218 bits (168), Expect = 5.486e-12 Identity = 114/521 (21.88%), Postives = 214/521 (41.07%), Query Frame = 1
Query: 46 SSPNKENQSRRSIKPRKSTNSSLNASFADKENV----DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCL--------------SNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEV-LKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKL-----------------NANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEK---SILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISG------------------VTTPKRRKINNDDTDDKFQIN-AYTNDAMKLFCDEE--YNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCF-PDKNIDSKQTLQIWTVDSPV 1425
S+P S + P + T +KE + D LA YID VR++E+ N L + E +++ +K+ Y E+ R++LDD A +L +E ++ E + L +LK+ LN+ + + + RK LEG L+ + ++ + L +E V+LENR +L EE++F K + +S E F + Q + ++QV++ K ++ + + E + + + A E+ + LR +L + S L++E +RI + Q L D E ++ K+ L+++E L+D K+AL+ E + LLEGE+ R +S T KR++++ ++++ ++ A++ A C +E +G I+L N SD+ + +++T DS++ Y F P + + Q + IW ++ V
Sbjct: 6 STPAGRRMSSTPLSPTRITR------LQEKEELSNLNDRLAIYIDKVRSLESENSVLHLQISEKEEVRSRELTGLKALYETELADARRSLDDTAKERARLQIELGKIRTEHEQLLQSYAKKDSDLAGCQARLKDVEALLNSKEASLA----TALSERKALEGSLADLQAQIHELEASLASARKQLGDETLLRVDLENRCQSLVEELEFRKNMFEEEIKDTRRRHETRLVEVDSGRQVEYEFKLAQALTDMR-QQHDDQVKVYKEEMEQTYMAKLENVRLSSEMNSSSASMAREELKEASLRVESLTAQLSGLQKEARGW--------------QDRINELESALAQEKDLSRRMLADKEREISEIRAKMQLQLEEYEQLLDVKLALDMEINAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGKRKRVDVEESEASSSVSIAHSASATGNVCIDELDVDGKFIRLHNTSDQDQPMVGFEMTRTIGDSSATYKFTPKYVLKAGQKVTIWASNAGV 501
BLAST of Lamin-B2 vs. Ensembl Cavefish
Match: lmnl3 (lamin-L(III)-like [Source:NCBI gene;Acc:103047028]) HSP 1 Score: 52.7582 bits (125), Expect = 7.739e-7 Identity = 107/481 (22.25%), Postives = 207/481 (43.04%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSL-QEERDCLSNKLKNETYSLNAM---KTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKN-------EICKCVELENRRITLTEEVDFYKKLNANS----KITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLN-ENRILQDKLNLKIQELSDLVDE-KIALEK-------------EFYVFTTLLEGEKTRCNISG------------------VTTPKRRKINNDDTDDKFQINAYTNDAMKLFCDE-EYNGGHIKLLNDSDKLININEW---KLTIITDDSTSVYCFPDKNI-DSKQTLQIWTVDSPV 1425
D LANYI+ VR +E+ +++ + E+ +++ +++ Y E+ RK LD A +L +E L ++ R +S K E NA+ ++ L ++Y L L+ + +D+ + + AL+N E + V++EN+ TL E++DF K + + ET + + + K E ++ L+++ + ++ LE+ + K N K + N+ F ++ K E+ + ++ QIS L + N +E R +E L+ ML+ E ++ +L+ K QE++D+ + + LE+ E + +LEGE+ R N+S + KR+ ++++ +++ + DE + G IKL N+SD ++ W K T D V+ P I ++ T+ IW+ + V
Sbjct: 43 DRLANYIERVRQLESDKSSMQLLLEEKEETTTRELRSVRLLYENELADARKTLDTTANERARLQIEYSQLCEDHRRLVSRNNKKEAELSNAVERWRSLEAALNSKEADYANLLAANRRLETDVADLRTHVDNLESALQNAKTQINSETLRRVDVENQIQTLQEQMDFQKHVTEQEVREMRSRHETRLVEVDSGRQKEFESKLAEAMQQLRQEHEAQIQQYKDDLERTFSAKLE-----NAKQVAVKNSDFA--TSTKEELAGTKLRLESQSLQISNLQTQ----NSTLEARVQE----LERMLDRERQVSHQRLSQKDQEMADMRQQMQTQLEEYQSLLDLKLMLDMEINAYRKMLEGEEKRLNLSPSPSQHSSISRTHAQGTRKAGSKKRKHEGASGLSPSYKVSQHSSSRGVVSIDEIDLMGNFIKLRNNSDTDQSLGGWVVRKRQSGTPD--VVFKIPKSCILRAEDTVTIWSAGAGV 506
BLAST of Lamin-B2 vs. Ensembl Sea Lamprey
Match: lmnb2 (lamin B2 [Source:ZFIN;Acc:ZDB-GENE-990630-13]) HSP 1 Score: 68.9366 bits (167), Expect = 1.584e-12 Identity = 114/499 (22.85%), Postives = 214/499 (42.89%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENL----------------KNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERD-----CLSNKLKNET-YSLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNK-------NKVALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTEDFEHCREKLE---KFYDNKCNEIMKAN-EKSILRYNTLFGENSNLKREI-ENLRNDNF----------AKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNIS---GV----------------TTP-KRRKINNDDTDDKF-----QINAYTNDAMKLFCDE-EYNGGHIKLLNDSDKLININEWKL-TIITDDSTSVYCFPDKNI-DSKQTLQIWTVDSPV 1425
D LA YI+ VR++E L K+E+Q + +++ Y E+ +R+ALDD + L ++ + Q ERD C +K + E +L ++ ++L ++ E L+ E D+ + N+ +K L+ E V+LENR +TL EE++F K+++ + + + TH + + +Q + +L+E R++ E + Y + ++ M+A EKSIL E +L I E+LR A + ++ L R+ E + + L + E L++ ++ ++ E L+D K+AL+ E + LLEGE++R N+S GV T P KR+++ + D ++ + + + + E + G + ++N+S+K + W L I D + Y F + + + QT+ IW ++ V
Sbjct: 28 DRLAAYIERVRSLEVDKARLLARVSMWEEEEEEQRQKSERQR------EATGGLRAAYDAELAEVRRALDDALGAKAALEIQLRLAQVERDEGRSRC--SKYEQEWNVALGRIRDMEVQLCAKEASLSTASGDKEYLETEVDDLRNQVNQLEGVLVSSKQQLEEETLARVDLENRMLTLQEELEFTKRIHEQEIHESRSK----RETHVLEIDGGQQQA--FEYKLSEALTELRQQHEEQVQLYRQELDQTMRAKLEKSIL-----TPEKQSLDISIREDLREATSRVGTLSSQLSAAQHDLALLQGRVRELEETLSHERDQSKRRLDESDRELAELREVMDEQLIEYEQLLDIKLALDMEIAAYRKLLEGEESRLNLSPEKGVQSSVVQTSTSASHSIRTMPGKRKRVQLEGFVDSMAQSQRSVSQHASASGSIGIKEVDMEGKSVTMVNNSEKDQPLGGWVLKRQIEDQAEIAYKFSSRYVLKAGQTVTIWAANAGV 507
BLAST of Lamin-B2 vs. Ensembl Nematostella
Match: EDO37225 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGD1]) HSP 1 Score: 87.4261 bits (215), Expect = 3.724e-18 Identity = 115/470 (24.47%), Postives = 214/470 (45.53%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQE-----------------NISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKL------NANSKI-TTETSFSIIQNTHNSDANDKNEQVEILKRQ-LTEDFEH----CREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRI--LQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTP----------KRR---KINNDDTDDKFQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKL--TIITDDSTSVYCF-PDKNIDSKQTLQIWTV 1413
D LA YID V+N+E N L++E ++ E+++ ++KS Y E+ R+ LD+ A K +E+ + NK E + + ++ ++++ N+ + ++L+G E ++ K AL+ E V+LENR +L EE +F K++ + S++ T ET +++ +D DK E + K Q L ED++ +E+ E Y +K E+ E+ L EN NL + ++ L + + + +AL +R+ Q +HDN + +L EN I L+ ++ +++ DL+ K+AL+ E + LLE E+TR I+ +P RR + ++T+ A++ F + + +G +IK+ N +K + W + + T+D SVY F P + S+ + +W+
Sbjct: 49 DRLATYIDRVKNLEQENSKLRSEVTVSRKTVEREVDSMKSLYETELADARRLLDETAKEKAKQQIESSKNSNDAQEFKNKFDKEAAARKKAEKELNDVRKLLHDKENQLTRRNQEALNLESVLRELQG------ECEELKDALKAAKYALEQETLTRVDLENRCQSLQEEQNFKKQMYDKELSDIRSQLKTVETKRVVVE----TDYKDKYEGLMAEKLQELREDYDSDARSFKEETELLYSSKFEELRIQRERDSEALAKLREENRNLSKSVDELSSQVHQLEAKNNALVSRVSDLQGLRAQDKEKHDNEI--LLRENEIAELRTSIDDALRDYEDLMGVKVALDMEITAYRKLLESEETRLEITPPASPVLGGSSSVSQTRRGNKRARTEETESTMTTTTTAEGAIQ-FTEADPDGKYIKIYNSGEKDEALGGWTIQRQVGTED-PSVYKFTPKYVLKSQSHVTVWSA 504
BLAST of Lamin-B2 vs. Ensembl Medaka
Match: ENSORLT00000011270.2 (lamin-A [Source:NCBI gene;Acc:101160250]) HSP 1 Score: 85.5001 bits (210), Expect = 4.714e-17 Identity = 112/482 (23.24%), Postives = 211/482 (43.78%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQE-------NISNYRKKLEGYEV----LKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNAN----SKITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRD------REHDNHLKDMLNENRILQD---KLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTP-----------------------KRRKINNDDTD---------DKFQINAYTNDAMKLFCDE-EYNGGHIKLLNDSDKLININEWKLTIITDDSTSV-YCFPDK-NIDSKQTLQIWT 1410
D LA YID VR++EA N L+ +++ +K+ Y E+ RK LD +A +L LE L+E+ L + + L A + +L+ +++ + EV LK + S + + L++E+ + V+ ENR TL EE++F K L++ +K E+ + N D K E + ++ Q + +E++EK Y+ K +++ +S R + L G E++ +R + Q+S L ++ + I RD RE D+ + + ++ R + D ++ ++ E +L+D K+AL+ E + LLEGE+ R +S P KRR+ N D++ + +I + + ++ DE + +G +++L N +D+ N+ W++ T + + FP K + + Q + IW
Sbjct: 35 DRLAVYIDKVRSLEAENACLRVRITESETEVTRELTGLKNAYEAELADARKTLDSVAKERARLQLELGKLREDHKELKARNTKKESDLAAALQRLKDLEALMNSKDASLTTALGEKRNLEVENRDLKAQVSKLDTGLGDARKQLQDEMLRRVDGENRIQTLKEELEFQKNLHSEELQETKRRHESRMVEMNNGQQQDFESKLAEALVEMRSQHELQIQLYKEEIEKTYNAK----LESARQSADRSSHLVGAAHE---ELQQIRTRLESTSAQLSQLQKQLAAREAKI--RDLEDALTRERDSTRRLLADKEREMADMRQRMQQQLDEYQELLDVKLALDMEICAYRKLLEGEEERLRLSPSPPPTRVTGSRSSVGRSVHSSAQSSPAKRRRPNEADSEASSYGGGALARTRITQQASASGRVTVDEVDLDGKYVRLSNKADEDQNLGSWQVRRQVGSGTPILFKFPAKFTLKAGQRVTIWA 507
BLAST of Lamin-B2 vs. Ensembl Medaka
Match: lmna (lamin A/C [Source:NCBI gene;Acc:101162240]) HSP 1 Score: 81.6481 bits (200), Expect = 7.561e-16 Identity = 113/495 (22.83%), Postives = 215/495 (43.43%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLK---NEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNY----------RKKLEGYEV--LKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKL----NANSKITTETSFSIIQNTHNSDANDKNEQVEI-LKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQD---KLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTP-------------------------------------KRRKINN-------DDTDDKFQINAYTNDAMKLFCDE-EYNGGHIKLLNDSDKLININEWKLTIITDDSTSV-YCFPDK-NIDSKQTLQIWTVDS 1419
D LA YID VR++EA N L+ +E ++L+ +D+ IK+ Y E+ R ALD +A +L L+ ++EE L + + L A + +L+ +++ ++ LE EV LK + + + + + L++E+ K V+ ENR T+ EE++F K + SK +E+ I + + +K + L+ Q E +E+LEK Y+++ + E++ E + +E L Q+SA ++ E + RE D + + +++R + + ++ ++++ +L+D K+AL+ E + TLLEGE+ R +S + P K+R++N+ T K I+ + + ++ +E + G I+L N SD+ ++ W++ D V Y FP K ++ + T+ IW
Sbjct: 32 DRLAVYIDKVRSLEAENAGLRLRISESESLVT---RDLSGIKAAYENELADARHALDQVAKEKARLQLDLGKIREEHKELKARNTKKELDLEAALARLRDLEALLNSKDAALATALGEKRNLEA-EVKDLKAQLAKLDMNLADARKQLQDEMLKRVDAENRLQTVKEELEFQKNIYNEETRESKRRSESRMVEIDCSRQQEFENKLAAALVELRAQHEEQVSIYKEELEKTYNSRLENARHSAERTTHLVGAAHEELQQTRSRLEGLTLQMTQLQKQLSASEAKVRELEEAL---SRERDLMRRRLEDKDREMAENRARMQQQLEDYQELLDIKLALDMEISHYRTLLEGEEERLRLS-PSPPSAKVIVTRSTGSSHASRLLHSSAVASSSRTSSGASSTKKRRLNDSVAASMVGGTVVKSHISQQASASGRIVVNEVDLEGKFIRLSNKSDEDQSLGSWQVKAQVGDGNPVTYKFPSKFSLKAGATVTIWAASG 518
BLAST of Lamin-B2 vs. Ensembl Medaka
Match: lmnl3 (lamin-L(III) [Source:NCBI gene;Acc:101168604]) HSP 1 Score: 76.2554 bits (186), Expect = 3.671e-14 Identity = 110/494 (22.27%), Postives = 212/494 (42.91%), Query Frame = 1
Query: 46 SSPNKENQSRRSIKPRKSTNSSLNASFADKENVDGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNY----RKKLEGYEVLKQEYSD--ISIENNKNKVA-----LKNEICKCVELENRRITLTEEVDFYKKLNANS----KITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDM-LNENRIL--QDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTP-----------------KRRKINNDDTDDKFQI-NAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSV-YCFPDKNI-DSKQTLQIWT 1410
S+P R + P + + D LANYI V+ +E + Q E+ ++ ++ Y EE+ +R+ALD+LA +L +E + +E+ L ++ + + L A T +++ +S+ RK L L E +D + +EN + +A L +EI + VE+EN+ TL E+++ K ++ + ET +++ + K E ++ L+ T + +E +EK + K +A E++ + +T E + ++E+LR+ L R F E D+E D + + L E +L + ++N +++ +L+D K+AL+ E + +LE E+ R +S T P KR+ + ++I T + + G ++++ N+SD+ + W + + S V + FP + QTL IW+
Sbjct: 6 STPAARGGRRGACSPSPGQPPRVQERGELRHLNDRLANYIQRVQELEQEKGAMLLRLQEQEEATARETRGVRRLYEEELADVRRALDELAAERARLQIEQGNQREDILKLQSRNQKKENDLAAAVTQRRKVEAVLSSKEAENRKLLSENGRLGGEVADLQVQLENAERLLAETKNQLSSEILRRVEMENQVQTLKEQLELQKNISRQEILEVRSRQETRLVEVESGRRREFESKLAETMQQLREDHTLQLQQYKEAMEKTFSTKLQNAQQAAEENGVSVSTAREELEASREKLESLRSQLQQNQKDKLVLEER---FQELQRTLDQERDAWQQRLSLKERELLSMRTQMNSQLENHQNLLDVKLALDMEINAYRKMLEVEEQRLQLS-PTPPRHTSVARVQEHHQLRGKKRKHEEATRSSPAYKICRRSTRKGGVTVAEVDVGGKYVQIQNNSDQEQPLGGWVVRRVYPHSGDVSFQFPPSCVLAGGQTLTIWS 495
BLAST of Lamin-B2 vs. Ensembl Medaka
Match: lmnl3 (lamin-L(III) [Source:NCBI gene;Acc:101168604]) HSP 1 Score: 75.0998 bits (183), Expect = 8.776e-14 Identity = 110/502 (21.91%), Postives = 214/502 (42.63%), Query Frame = 1
Query: 31 LIMFNSSPNKENQSRRSIKPRKSTNSSLNASFADKENVDGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNY----RKKLEGYEVLKQEYSD--ISIENNKNKVA-----LKNEICKCVELENRRITLTEEVDFYKKLNANS----KITTETSFSIIQNTHNSDANDK-NEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDM-LNENRIL--QDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTP-----------------KRRKINNDDTDDKFQI-NAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSV-YCFPDKNI-DSKQTLQIWTVDS 1419
+ S+P R + P + + D LANYI V+ +E + Q E+ ++ ++ Y EE+ +R+ALD+LA +L +E + +E+ L ++ + + L A T +++ +S+ RK L L E +D + +EN + +A L +EI + VE+EN+ TL E+++ K ++ + ET +++ + K E ++ L+ T + +E +EK + K +A E++ + +T E + ++E+LR+ L R F E D+E D + + L E +L + ++N +++ +L+D K+AL+ E + +LE E+ R +S T P KR+ + ++I T + + G ++++ N+SD+ + W + + S V + FP + QTL IW+ +
Sbjct: 1 MASATSTPAARGGRRGACSPSPGQPPRVQERGELRHLNDRLANYIQRVQELEQEKGAMLLRLQEQEEATARETRGVRRLYEEELADVRRALDELAAERARLQIEQGNQREDILKLQSRNQKKENDLAAAVTQRRKVEAVLSSKEAENRKLLSENGRLGGEVADLQVQLENAERLLAETKNQLSSEILRRVEMENQVQTLKEQLELQKNISRQEILEVRSRQETRLVEVESGRRREFESKLAETMQQLREDHTLQLQQYKEAMEKTFSTKLQNAQQAAEENGVSVSTAREELEASREKLESLRSQLQQNQKDKLVLEER---FQELQRTLDQERDAWQQRLSLKERELLSMRTQMNSQLENHQNLLDVKLALDMEINAYRKMLEVEEQRLQLS-PTPPRHTSVARVQEHHQLRGKKRKHEEATRSSPAYKICRRSTRKGGVTVAEVDVGGKYVQIQNNSDQEQPLGGWVVRRVYPHSGDVSFQFPPSCVLAGGQTLTIWSSGA 498
BLAST of Lamin-B2 vs. Ensembl Medaka
Match: lmnb2 (lamin B2 [Source:NCBI gene;Acc:101158263]) HSP 1 Score: 73.1738 bits (178), Expect = 2.800e-13 Identity = 105/469 (22.39%), Postives = 201/469 (42.86%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQE--ERDCLSNKLKNETYSLNAMKTDMIE--LQENISNYRKKLEGYEVLKQEYSDI----SIENNKNKVA---LKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSIIQNTHNSDANDKNE-------QVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIE-QRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPK---------------RRKINN-------DDTDDKFQIN-AYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTS-VYCF-PDKNIDSKQTLQIWTVDS 1419
D LA YI+ VR +E N+ L + E +++ +K+ Y E+ LR+ LD+ A +L ++ Q E S K K + + + +E L ++ + L L E ++ + + + VA L+ E V+LENR +L+E++DF + N + E+ Q D+ + E ++ L++Q E +E+LEK + K ++E S + E + IE+L + Q+ +RI E + +RDR H ++ E L++ ++ ++ E +L+D K+AL+ E + LLEGE+ R +S + + +RK + +++ ++ T+ C + +G +KL N++D+ + W+L D+ VY F P + + Q++ +W+ D+
Sbjct: 40 DRLAVYIERVRALELENDRLMVKVSEKEEVTTREVTGLKALYEAELADLRRVLDETAKERARLQIDLGKAQADLEEATRSAKKKEADLAAAVSRANSLEGQLHKSEAALSTALSQSAALTSELGEVKSLLAKAEDGHAVAKRQLEAETLMRVDLENRCQSLSEDLDFRR--NMFDEEMRESRRHQEQRIVEVDSGARQEYEFKLTQALQDLRKQHDEQVSFYKEELEKTFQAKLENAHVSSEMSNAAMDAAREELQESRSRIESLSYQLSSLQKQVGTSEDRIRELEEILSAERDR-HRRAMERKEQEMSELREGMDAQLSEYQELLDVKLALDVEINAYRKLLEGEEHRLKLSPSPSARVTVSRVTGSSSSRSTKRKWSEVEAQEEAGQAEEQLLVSEEATSTGSVSICPTDMDGTSVKLTNETDQDQPLGSWRLRRQVDNGEEVVYKFSPKFVLKAGQSVTVWSADA 505
BLAST of Lamin-B2 vs. Planmine SMEST
Match: SMESG000047473.1 (SMESG000047473.1) HSP 1 Score: 1056.2 bits (2730), Expect = 0.000e+0 Identity = 525/525 (100.00%), Postives = 525/525 (100.00%), Query Frame = 1
Query: 37 MFNSSPNKENQSRRSIKPRKSTNSSLNASFADKENVDGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKRRKINNDDTDDKFQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFPDKNIDSKQTLQIWTVDSPVMDDVDNIRLNISLPDLSVLRSCTLTNDMDGFEASFKLKRAEPRKILKAHPRNVQTNERCAIM 1611
MFNSSPNKENQSRRSIKPRKSTNSSLNASFADKENVDGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKRRKINNDDTDDKFQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFPDKNIDSKQTLQIWTVDSPVMDDVDNIRLNISLPDLSVLRSCTLTNDMDGFEASFKLKRAEPRKILKAHPRNVQTNERCAIM
Sbjct: 1 MFNSSPNKENQSRRSIKPRKSTNSSLNASFADKENVDGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKRRKINNDDTDDKFQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFPDKNIDSKQTLQIWTVDSPVMDDVDNIRLNISLPDLSVLRSCTLTNDMDGFEASFKLKRAEPRKILKAHPRNVQTNERCAIM 525
BLAST of Lamin-B2 vs. Planmine SMEST
Match: SMESG000047473.1 (SMESG000047473.1) HSP 1 Score: 1052.74 bits (2721), Expect = 0.000e+0 Identity = 525/538 (97.58%), Postives = 531/538 (98.70%), Query Frame = 1
Query: 37 MFNSSPNKENQSRRSIKPRKSTNSSLNASFADKENVDGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKRRKINNDDTDDKFQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFPDKNIDSKQTLQIWTVDSPVMDDVDNIRLNISLPDLSVLRSCTLTNDMDGFEASFKLKRAEPRKILKAHPRNVQTNERCAIM*FRFSNWVLIYIF 1650
MFNSSPNKENQSRRSIKPRKSTNSSLNASFADKENVDGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKRRKINNDDTDDKFQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFPDKNIDSKQTLQIWTVDSPVMDDVDNIRLNISLPDLSVLRSCTLTNDMDGFEASFKLKRAEPRKILKAHPRNVQTNERCAI+ +++++ F
Sbjct: 1 MFNSSPNKENQSRRSIKPRKSTNSSLNASFADKENVDGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKRRKINNDDTDDKFQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFPDKNIDSKQTLQIWTVDSPVMDDVDNIRLNISLPDLSVLRSCTLTNDMDGFEASFKLKRAEPRKILKAHPRNVQTNERCAIIVLFSFLYLMLWRF 538
BLAST of Lamin-B2 vs. Planmine SMEST
Match: SMESG000018461.1 (SMESG000018461.1) HSP 1 Score: 476.863 bits (1226), Expect = 6.028e-164 Identity = 268/505 (53.07%), Postives = 357/505 (70.69%), Query Frame = 1
Query: 79 SIKPRKSTNSSLNASFADKENVDGLANYI-DYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGVTTPKRRKIN--NDDTDDKFQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFPDKNIDSKQTLQIWTVDS-PVMDDVDNIRLNISLPDLSVLRSCTLTNDMDGFEASFKLKRAEPRKILKAHPRN 1581
S + R+STNS +N+ F DK++ G A+ + +Y+RNI NE LK E Q LI+S++K+ IK+T GEEID LRKAL+D+ +S IKL +NK+++EE++ L+NKLKNE+ SLN +K + IE+QE I+NYR+KLEGYE LKQ+Y +IS ENNKNK+ +KN++ KCVELENR TLTEE+D+YK+LN SK T ET+ IQN N DA N +VEILK QLT DFEHC+E+LEKFY+NK N++ K NE L EN LK+EIE +R DNF K + I+ LNNRI + NEF E R+R+ +N LK++L E L+ L I ELS EK A+E E F ++LE E R + G ++PKR++I N + KF I+A+TND +KL+CDE+ NG +IKL+ND+D IN+NEWK+ I++DD VYCFP++ I K+ L +W D+ VMDD DNIR+N++LPD S SC LTNDM FEASF+LKR RK +KAH RN
Sbjct: 2 SNRERESTNSPINSPFLDKKDTSGSASKLGEYIRNIGDENEKLKVENQKLIDSFKKETNLIKATCGEEIDCLRKALEDVTSSKIKLAFDNKNMREEQEFLNNKLKNESSSLNILKKETIEMQEKINNYRQKLEGYEALKQDYLEISSENNKNKITMKNDMYKCVELENRIATLTEEIDYYKRLNDRSKTTLETN---IQNAANFDA-KVNAKVEILKMQLTADFEHCKEELEKFYENKSNDVNKLNE-------NLAIENMKLKKEIEEMRIDNFDKIHTINNLNNRISNINEFNENRNRQTENRLKEILVEKHSLKCDLESTINELSATKAEKAAIENELSEFRSILESETNRHSTGGGSSPKRKRICKINPTNEAKFDISAFTNDRVKLYCDEQCNGDYIKLMNDTDNPINLNEWKIEIVSDDFKDVYCFPNRFIKGKRVLNVWRKDALSVMDDEDNIRMNVALPDFSKSFSCELTNDMYEFEASFQLKRTYQRKFIKAHQRN 495
BLAST of Lamin-B2 vs. Planmine SMEST
Match: SMESG000009886.1 (SMESG000009886.1) HSP 1 Score: 119.398 bits (298), Expect = 4.243e-28 Identity = 129/535 (24.11%), Postives = 242/535 (45.23%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETYSLNAMKTDMIELQENISNYRKKLEGYEVLKQEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSII--------QNTHNSDANDKNEQVEILKRQLTEDFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSFNEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCNISGV-----------TTPKRRKI----------NNDDT----DDKFQINAYTNDAMKLFCDEEYNGGHIKLLNDSDKLININEWKLTIITDDSTSVYCFPDK-NIDSKQTLQIWTVDS-----PVMDDVDNIRLNISLPDLSVLRSCTLTNDMDGFEASFKLKRAEPRKIL-----KAHPRNVQTNE--RCAIM 1611
D A+YIDYVR++E + E L + Q++ ++ +I IK Y +E+ SLRK +DDLA + +E K+ +E+ KL+ L ++ + L+ ++S R E Y L ++ + + K L EI ++EN+ +TL E+++F ++L + +I Q + S D ++ ++ + E+FE + + E+ + + ++ K N+++ E + + E + K ++ AL RI + E + L + E+ L++ L ++ E S L+ KIAL++E ++ LLE E+TRCNIS + KRRK+ N +T + ++++ + ++ + +G +KL+N +DK I I W L I D+ + Y F +I +K +W+ D+ P D V + S ++ + LTN + EA+ L + R + K R+++T E +C++M
Sbjct: 90 DRFASYIDYVRSLEIAKEKLTKKIQSISKTETSEIDKIKKLYEDELRSLRKMVDDLAKERANIEIELKNAKEDAIAYRKKLEKRDLDLQNLQRKLENLERDLSKQRMDSERYSTLLVQHDTLEKKCAKLSKELDGEILLRTDIENKNVTLKEQLEFNERLYNEENVKIRQHHIVIEEQIEDRKQAEYESKLAD---ELRAIREETAEEFESYKLEFEQSFTLRLADLKKINQQTNENVTKTRDEMLTWRSKAEQREQELAMKTSENDALKRRIKDLESLLNTERNEFEGQLMKLRGESDNLRNDLEKRLDEFSSLMSTKIALDQEILMYRKLLESEETRCNISVAADGDTSFSALNASSKRRKVGERGEYVLPDNRGNTVSCGRESYKVDLVSRGNVEFSSKPDCSGKFVKLINPTDKDICIGGWMLKYIADNQETSYKFHHNLHIKAKSDCTVWSSDANETHNPPSDLVMKGQRFFSGSNIKI----NLTNADNQEEANCVLAKEHTRSSVYNYNRKVAARSLRTGEESKCSMM 617
BLAST of Lamin-B2 vs. Planmine SMEST
Match: SMESG000062826.1 (SMESG000062826.1) HSP 1 Score: 65.855 bits (159), Expect = 4.865e-11 Identity = 94/359 (26.18%), Postives = 164/359 (45.68%), Query Frame = 1
Query: 145 DGLANYIDYVRNIEASNENLKNEKQNLIESYEKDIYTIKSTYGEEIDSLRKALDDLATSTIKLNLENKSLQEERDCLSNKLKNETY-------SLNAMKTDMIELQENISNYRKKLEGYEVLK----QEYSDISIENNKNKVALKNEICKCVELENRRITLTEEVDFYKKLNANSKITTETSFSIIQNTHNSDANDKNEQVEILKRQLTE---DFEHCREKLEKFYDNKCNEIMKANEKSILRYNTLFGENSNLKREIENLRNDNFAKDNQISALNNRIVSF------------NEFIEQRDREHDNHLKDMLNENRILQDKLNLKIQELSDLVDEKIALEKEFYVFTTLLEGEKTRCN 1143
D ANYID VRN+E N+ L +E +L + + K+ IK+ Y ++ LR++LD + ++ ++ +L++ +L + T +++ M + + + + I+N RK+L G E K +E + E N K L+ E + + N +L ++++F KK+ S++ S +T N D +NE + L+ TE + +E Y K EI + + L EN+ LK ++ +RN + ++ A NN + EF D E +N K++LN L+ L EL L+D K++LE E + +LEGE+ R N
Sbjct: 96 DRFANYIDKVRNLEDENKRLSDELVDLKDQWGKETARIKTFYDNDMIQLRRSLDQAEGAKAQMEMKINTLEDLILEAQTELNDATQLHLADKETIDKMASTLSDYEHEIANLRKRLGGLEEEKVRDNKEIMRLKEELNLLKQDLEKETLEHITAHNELQSLVDQIEFLKKI-FESEVRELASLVYKDSTENKDFW-RNEMAQALRDIQTEYDRKLDTLHYDMEAQYTLKIQEIRTTQSQENVETVQLREENTRLKDQLAEMRN----RLPELEARNNELERLLELLRREIEEKNREF----DLEKNNLRKELLNRKAELEGIL----IELQILLDAKLSLELEIIAYRKMLEGEEYRVN 440 The following BLAST results are available for this feature:
BLAST of Lamin-B2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Lamin-B2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Lamin-B2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Lamin-B2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Lamin-B2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Lamin-B2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Lamin-B2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Lamin-B2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Lamin-B2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Lamin-B2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Lamin-B2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Lamin-B2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Lamin-B2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Lamin-B2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30010297 ID=SMED30010297|Name=Lamin-B2|organism=Schmidtea mediterranea sexual|type=transcript|length=1732bpback to top protein sequence of SMED30010297-orf-1 >SMED30010297-orf-1 ID=SMED30010297-orf-1|Name=SMED30010297-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=526bp MFNSSPNKENQSRRSIKPRKSTNSSLNASFADKENVDGLANYIDYVRNIEback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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