G_PROTEIN_RECEP_F1_2 domain-containing protein

Overview
NameG_PROTEIN_RECEP_F1_2 domain-containing protein
Smed IDSMED30010212
Length (bp)1259
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30010212) t-SNE clustered cells

Violin plots show distribution of expression levels for G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30010212) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30010212) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30010212) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30010212

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30010212h1SMcG0008165 SmedASXL_004099SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Match: SSTR4 (somatostatin receptor 4 [Source:HGNC Symbol;Acc:HGNC:11333])

HSP 1 Score: 50.447 bits (119), Expect = 4.097e-6
Identity = 45/217 (20.74%), Postives = 97/217 (44.70%), Query Frame = 2
Query:   86 VWTFIIVFGVVGNIMTVLV-LQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKH----SVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTIC--EWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHM---KNIREKMKTHQHIIK 706
            ++  + + G+VGN + + V L+Y  M T +T+IYL  LA+AD +F++          + F       +H    SV C  V        + SV+ L  +++DR   V+ P ++  +     AK    GV L  +++         +  +       C  +W    +  +F ++  +   +LP L + +  ++I+ K++ +      +++ ++ + I +
Sbjct:   53 IYALVCLVGLVGNALVIFVILRYAKMKT-ATNIYLLNLAVADELFML---------SVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITR 259          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Match: CCR1 (C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602])

HSP 1 Score: 49.6766 bits (117), Expect = 6.091e-6
Identity = 58/205 (28.29%), Postives = 100/205 (48.78%), Query Frame = 2
Query:   86 VWTFIIVFGVVGNIMTVLVL-QYPNMNTMSTSIYLKALAIADMIFLI---FSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLIS---VHSNKTICEWSDVRFKLIFP--------IFDLIFVN----ILPSLTMLIANVMII 643
            +++ + V G+VGNI+ VLVL QY  +  M TSIYL  LAI+D++FL    F +  +L D   F            C I++ F +T  Y  ++ ++ +T+DR   ++    + +      A++   GV      I +  +W+++ L S   ++ +KT  E++     L FP        +F  + +N    +LP L M+I    II
Sbjct:   40 LYSLVFVIGLVGNILVVLVLVQYKRLKNM-TSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVF--------GDAMCKILSGFYYTGLYSEIFFIILLTIDRYLAIVHAVFALR------ARTVTFGV------ITSIIIWALAILASMPGLYFSKTQWEFTHHTCSLHFPHESLREWKLFQALKLNLFGLVLPLLVMIICYTGII 223          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: npr-9 (Galanin-like G-protein coupled receptor npr-9 [Source:UniProtKB/Swiss-Prot;Acc:Q23497])

HSP 1 Score: 62.3882 bits (150), Expect = 2.552e-10
Identity = 45/142 (31.69%), Postives = 74/142 (52.11%), Query Frame = 2
Query:   50 ETVKVIRNICIVVWTF---IIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFM---FFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVC 457
            +T+   R I I++ T    II+ G+VGN + V+V     M   ST+  +  LAI+D++FL+  V    +D+    + FP          C ++N F  T  Y SVW L  + LDR   V++P +S    T++T ++T+  +C
Sbjct:   34 DTISFERKIGIIIPTIFAVIILVGLVGNALVVIVAFGRQMRN-STNTLIIGLAISDLMFLLLCVPFTAVDYAAPTWIFPEWT-------CSMINFFQHTSAYCSVWTLTLMALDRYLAVVYPVESM---TLRTPRNTVIALC 164          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: frpr-9 (FMRFamide Peptide Receptor family [Source:UniProtKB/TrEMBL;Acc:C7FZU1])

HSP 1 Score: 57.3806 bits (137), Expect = 1.154e-8
Identity = 75/293 (25.60%), Postives = 128/293 (43.69%), Query Frame = 2
Query:   98 IIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPM--------QLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMW---SVSSLISVHSNKTICE--WSDVRFKLIFPI------FDLIFVNILPSLTMLIANVMIIAKVKH---MKNIREKMKTHQHIIKENV-------ISNL-SLENKMNSNLLKPPELVPMNSLSIQKASTSDKRRDRKTSSLTKMLMTINIFFI 886
            I +FG + N++ V+V   P M     + +L  L+I+D++ L+ +       FM  FP+         L   + VF       G +     V+L V V++ R   V  PF+++++ + +  K  I G  +  ++IN H  W    +    S++ N  I     + +R K  + +      + LI   I+P +T++I N  I+  +K    M+N +   K+ Q  I  N         S L     ++N N LK P L+  N  S+         RDR   S+T ML+ I   F+
Sbjct:   37 IAIFGFITNVINVIVFCDPEMRCSLVNHFLLVLSISDLVLLVCNF------FMLIFPVIASMSNSYLLHDYYPVFLWFAYPVGLSTQTCGVYLTVLVSVHRYLGVCHPFRAKRWVSGKPVKWAIIGSIIFSIVINLH-TWLELDIRPCYSINFNAPISSIILTSLRQKSSYNLITKCIMYTLIMF-IIPFITLIIVNCRIVVALKESTRMRNGQSMKKSTQSRIMNNFRMLKGAKYSELFGRFGRLNFNPLKTPSLLKTNGNSL---------RDR---SVTLMLLAIVAIFL 309          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: frpr-9 (FMRFamide Peptide Receptor family [Source:UniProtKB/TrEMBL;Acc:C7FZU1])

HSP 1 Score: 54.6842 bits (130), Expect = 7.715e-8
Identity = 72/302 (23.84%), Postives = 131/302 (43.38%), Query Frame = 2
Query:   98 IIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPM--------QLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMW---SVSSLISVHSNKTICE--WSDVRFKLIFPI------FDLIFVNILPSLTMLIANVMIIAKVKH---MKNIREKMKTHQ-----HIIKENVISNLSLE------------NKMNSNLLKPPELVPMNSLSIQKASTSDKRRDRKTSSLTKMLMTINIFFI 886
            I +FG + N++ V+V   P M     + +L  L+I+D++ L+ +       FM  FP+         L   + VF       G +     V+L V V++ R   V  PF+++++ + +  K  I G  +  ++IN H  W    +    S++ N  I     + +R K  + +      + LI   I+P +T++I N  I+  +K    M+N +   K+ Q       + + +++N  +              ++N N LK P L+  N  S+         RDR   S+T ML+ I   F+
Sbjct:   37 IAIFGFITNVINVIVFCDPEMRCSLVNHFLLVLSISDLVLLVCNF------FMLIFPVIASMSNSYLLHDYYPVFLWFAYPVGLSTQTCGVYLTVLVSVHRYLGVCHPFRAKRWVSGKPVKWAIIGSIIFSIVINLH-TWLELDIRPCYSINFNAPISSIILTSLRQKSSYNLITKCIMYTLIMF-IIPFITLIIVNCRIVVALKESTRMRNGQSMKKSTQSRFTWKSLDKRIMNNFRMLKGAKYSELFGRFGRLNFNPLKTPSLLKTNGNSL---------RDR---SVTLMLLAIVAIFL 318          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: trhr-1 (Thyrotropin-Releasing Hormone Receptor [Source:UniProtKB/TrEMBL;Acc:Q95YD7])

HSP 1 Score: 53.1434 bits (126), Expect = 1.797e-7
Identity = 63/279 (22.58%), Postives = 134/279 (48.03%), Query Frame = 2
Query:   86 VWTFIIVFGVVGNIMTV-LVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTIC----EWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVK-HMKNIREKMKTHQHIIKENVISNLSLENKMNSNLLKPPELVPMNSLSIQKASTSDKRRDRKT-SSLTKMLMTINIFFIISTLP 901
            V++ I V GV+GN++ + +VL+   M T  T+ YL +LA +D +F   S+  +++      P       S+ C ++    +     S   ++  T++R + +  P+K+R  CT++ A   I G+ +  ++ ++++++ +++LI      T C    E +   +K++F + D +   +LP    ++ +++I AK+   +    +K+K     +K  + + + +E    S+         M   S + +  S KR   K  + + KML  +   F +  LP
Sbjct:   38 VFSAISVIGVLGNLLVITVVLKVRGMKT-PTNCYLVSLAASDTLFFFASMPHEMM--YLLGPNDHYLFGSLGCVLLTYLPYLAMNTSSLSILAFTIERYYGICNPYKARTMCTVKRATCIICGIWIFSMLYHSYWLF-LATLIK-DDIGTSCSFRLERNSHAYKIVF-LLDFVLWYVLP----IMCDIIIYAKIGITLSQCGDKIKKS---VKPKIPNEVIVEKSKTSS-------TSMGHYSGRDSHISGKRNSAKGRNQVVKMLAIVVAVFAVCWLP 296          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: Y70D2A.1 (pep chromosome:WBcel235:X:14918836:14923942:1 gene:WBGene00013496.1 transcript:Y70D2A.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y70D2A.1)

HSP 1 Score: 52.373 bits (124), Expect = 3.808e-7
Identity = 85/340 (25.00%), Postives = 139/340 (40.88%), Query Frame = 2
Query:   95 FIIVFGVVGNIMTVLVLQYPNMNTMS-TSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVF--CHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPF----KSRKFCTMQTAKSTIAGVCLV---CVMINTHFMWSV---SSLISVHSNKTICEWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNSNLLKPPELVPMNSLSIQKASTSDKRRDRKTSSLTKMLMTINIFFIISTLPLLIYDLAYWFIDMNLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFR 1075
            FII+FG+VG+++TV+ L +P +   S    YL  LA+ D++   FSV   +   M+   ++   K S F   HI       +   SVW++VF+TL +   V  PF    +SRK C +  A + +   C+     V  N H +  +   S L+SV     +C+     + +I+     +   I P   +   N+ I+   ++ K  R++M                 E   NS                +K+   +KR       L  +L  I I F + T+P     +        L+  T     G  IF    +V  L +  F+M+F  YC+  P  R
Sbjct:   46 FIIIFGIVGDVLTVVTLTHPLLRKSSIIYTYLTLLAMTDLL-TQFSVIPMI---MWLLDIRACSKSSAFFYAHIGFPLANALMGSSVWIVVFLTLSQYMAVCKPFAYGLRSRKICYVLFALAYMFNFCIYAPWAVKKNVHDISDLVPESFLVSV-CPYVVCDAKRPDWFVIYETARELISRIFPFFLVAFLNIKILITYRNTK--RDRM-----------------ERLANSQ----------KKFMFEKSEKEEKR-------LFILLFAIVIVFFVCTIPAAPLTI--------LVADTKNNNVGFQIF--RAVVNLLEFTKFAMNFYFYCLINPDIR 334          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: CNMaR (gene:FBgn0053696 transcript:FBtr0091684)

HSP 1 Score: 82.0333 bits (201), Expect = 1.410e-16
Identity = 81/366 (22.13%), Postives = 151/366 (41.26%), Query Frame = 2
Query:  110 GVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTICEW-SDVRFKL-IFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVIS-------------------NLSLENKMNSNLLKPPELVPMNS----------------------LSIQKASTSDKRRDRKTSSLTKMLMTINIFFIISTLP-LLIYDLAYWFIDMNLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFR 1075
            G +GNI++V V     +  +S+S YL ALA++D  FL     G    ++ F  + +  ++  FC     F +  ++ SVW +V  T++R   VI+P K +  CT++ AK  +  + LV  +    ++     +     N TIC+  S+ + +L +F  +D I V  +P  T+ + N      V     +R  +  H+   + N +                    + SL+ + ++      +    N                         I +     K ++     +TKML+ ++  F+   LP  L+   AYW        +T+          L+ + +  +  +F ++F+LYC+SG  FR
Sbjct:   73 GSIGNILSVFVFFRTKLRKLSSSFYLAALAVSDTCFL----AGLFAQWLNFLNVDIYNQN-YFCQFFTFFSYLASFCSVWFVVAFTVERFIAVIYPLKRQTMCTVRRAKIVLFCLTLVGCLHCLPYIVIAKPVFMPKLNTTICDLNSEYKEQLALFNYWDTIVVYAVPFTTIAVLNTCTGCTVWKFATVRRTLTMHKMKPQTNSMPSNSSNSSGGASSAVASYRLSASLKRQKSTGTHPSGQHNVANRQTDDQEQQQQSQQHQINNCQHHCEITQKPARRKVQNSSQLKVTKMLLIVSTVFVCLNLPSCLLRIEAYW--------ETESARNQNSTIALQYIFHAFFITNFGINFVLYCVSGQNFR 425          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: Proc-R (gene:FBgn0029723 transcript:FBtr0100552)

HSP 1 Score: 60.4622 bits (145), Expect = 1.593e-9
Identity = 42/129 (32.56%), Postives = 69/129 (53.49%), Query Frame = 2
Query:   98 IIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFL----IFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVM 472
            + V G++GN +++ VL    M   +T+IYL ALAI D+ +L    I S+  Q  D+  +      Q +  F  + + FG    YIS+++ V  T++R   + +P K + FCT   AK  IA V + C++
Sbjct:   50 VFVIGLLGNSVSIYVLTRKRMR-CTTNIYLTALAITDIAYLTCQLILSL--QHYDYPKYHFKLYWQLYGYFVWLCDSFG----YISIYIAVCFTIERFIAIRYPLKRQTFCTESLAKKVIAAVAIFCLL 171          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: Proc-R (gene:FBgn0029723 transcript:FBtr0070713)

HSP 1 Score: 60.4622 bits (145), Expect = 1.593e-9
Identity = 42/129 (32.56%), Postives = 69/129 (53.49%), Query Frame = 2
Query:   98 IIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFL----IFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVM 472
            + V G++GN +++ VL    M   +T+IYL ALAI D+ +L    I S+  Q  D+  +      Q +  F  + + FG    YIS+++ V  T++R   + +P K + FCT   AK  IA V + C++
Sbjct:   50 VFVIGLLGNSVSIYVLTRKRMR-CTTNIYLTALAITDIAYLTCQLILSL--QHYDYPKYHFKLYWQLYGYFVWLCDSFG----YISIYIAVCFTIERFIAIRYPLKRQTFCTESLAKKVIAAVAIFCLL 171          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: Proc-R (gene:FBgn0029723 transcript:FBtr0100551)

HSP 1 Score: 60.4622 bits (145), Expect = 1.593e-9
Identity = 42/129 (32.56%), Postives = 69/129 (53.49%), Query Frame = 2
Query:   98 IIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFL----IFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVM 472
            + V G++GN +++ VL    M   +T+IYL ALAI D+ +L    I S+  Q  D+  +      Q +  F  + + FG    YIS+++ V  T++R   + +P K + FCT   AK  IA V + C++
Sbjct:   50 VFVIGLLGNSVSIYVLTRKRMR-CTTNIYLTALAITDIAYLTCQLILSL--QHYDYPKYHFKLYWQLYGYFVWLCDSFG----YISIYIAVCFTIERFIAIRYPLKRQTFCTESLAKKVIAAVAIFCLL 171          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: Proc-R (gene:FBgn0029723 transcript:FBtr0070714)

HSP 1 Score: 60.4622 bits (145), Expect = 1.593e-9
Identity = 42/129 (32.56%), Postives = 69/129 (53.49%), Query Frame = 2
Query:   98 IIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFL----IFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVM 472
            + V G++GN +++ VL    M   +T+IYL ALAI D+ +L    I S+  Q  D+  +      Q +  F  + + FG    YIS+++ V  T++R   + +P K + FCT   AK  IA V + C++
Sbjct:   50 VFVIGLLGNSVSIYVLTRKRMR-CTTNIYLTALAITDIAYLTCQLILSL--QHYDYPKYHFKLYWQLYGYFVWLCDSFG----YISIYIAVCFTIERFIAIRYPLKRQTFCTESLAKKVIAAVAIFCLL 171          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: si:dkey-1h24.2 (si:dkey-1h24.2 [Source:ZFIN;Acc:ZDB-GENE-060503-482])

HSP 1 Score: 61.6178 bits (148), Expect = 7.035e-10
Identity = 85/392 (21.68%), Postives = 168/392 (42.86%), Query Frame = 2
Query:   47 PETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLI-----DFMFFFPMQLRQKHSVFCHIVNLF-GFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKT------IC--EWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNSN----LLKPPELVPMNSLSIQKASTSDKRRDRKTSS-------LTKMLMTINIFFIISTLPLLIYDLAYWFIDMNLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFRWQALYMVGLCDKFENTNMKSRQGN 1147
            P   K + ++ I++++ + +  V GN++ ++VL         T+ +L +LA++D++  IF +   LI     DF+F          +  C  V  F G +V+ IS + LV + ++R   +  P KSR + T   A   IA   ++ V I   +   V S++ V  NKT      +C  EW   + +  + +  L  +  +P + M+IA  +I  ++        + K     +K  +   LS  +  +      + K P  + +++L+      +D+ R   + +       + +ML+ I   F +  +PL   +    F  ++      G    P+ F     +  L Y    ++ ++YC    +FR   L   G C +  +   K ++G+
Sbjct:   25 PTRPKEMDSVRIILYSLVFLLSVFGNLLIIVVLIVNKRMRTVTNSFLLSLAVSDLMMAIFCIPFNLIPSLLEDFIF---------GAAMCKTVAYFMGISVS-ISTFSLVAIAIERYSAICNPLKSRAWQTRSHAYKVIAATWVLSVAIMVPY--PVFSIL-VPFNKTNNITAHMCRLEWPISQVEQTWYVLLLSILFFIPGVVMIIAYGLISRELYRGIQFELEQKKDTSGVKNGLNGGLSSCHDESDGCYIQVSKKPPAMELSTLTTSGTVKTDRPRSNTSEAKLIAKKRVIRMLIIIVAMFFVCWMPLYTANTWKAFDQISAQRALSG---APISF-----IQLLSYTSACVNPIIYCFMNTRFRKALLATFGCCRRPCHNRRKRKEGD 395          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: si:dkey-1h24.2 (si:dkey-1h24.2 [Source:ZFIN;Acc:ZDB-GENE-060503-482])

HSP 1 Score: 61.6178 bits (148), Expect = 7.460e-10
Identity = 89/393 (22.65%), Postives = 169/393 (43.00%), Query Frame = 2
Query:   47 PETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLI-----DFMFFFPMQLRQKHSVFCHIVNLF-GFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKT------IC--EWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNSN----LLKPPELVPMNSLSIQKASTSDKRRDRKTSS-------LTKMLMTINIFFIISTLPLLIYDLAYW-FIDMNLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFRWQALYMVGLCDKFENTNMKSRQGN 1147
            P   K + ++ I++++ + +  V GN++ ++VL         T+ +L +LA++D++  IF +   LI     DF+F          +  C  V  F G +V+ IS + LV + ++R   +  P KSR + T   A   IA   ++ V I   +   V S++ V  NKT      +C  EW   + +  + +  L  +  +P + M+IA  +I  ++        + K     +K  +   LS  +  +      + K P  + +++L+      +D+ R   + +       + +ML+ I   F +  +PL  Y    W   D    I     L G  I  ++ L YT       ++ ++YC    +FR   L   G C +  +   K ++G+
Sbjct:   49 PTRPKEMDSVRIILYSLVFLLSVFGNLLIIVVLIVNKRMRTVTNSFLLSLAVSDLMMAIFCIPFNLIPSLLEDFIF---------GAAMCKTVAYFMGISVS-ISTFSLVAIAIERYSAICNPLKSRAWQTRSHAYKVIAATWVLSVAIMVPY--PVFSIL-VPFNKTNNITAHMCRLEWPISQVEQTWYVLLLSILFFIPGVVMIIAYGLISRELYRGIQFELEQKKDTSGVKNGLNGGLSSCHDESDGCYIQVSKKPPAMELSTLTTSGPVKTDRPRSNTSEAKLIAKKRVIRMLIIIVAMFFVCWMPL--YSANTWKAFDQ---ISAQRALSGAPISFIQLLSYT----SACVNPIIYCFMNTRFRKALLATFGCCRRPCHNRRKRKEGD 419          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: nmur3 (neuromedin U receptor 3 [Source:ZFIN;Acc:ZDB-GENE-130530-567])

HSP 1 Score: 60.4622 bits (145), Expect = 1.626e-9
Identity = 44/138 (31.88%), Postives = 77/138 (55.80%), Query Frame = 2
Query:   83 VVWTFIIVF--GVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGV---CLVCVMINT 481
            V  T+I++F  GV+GN++T  V+         T++YL +LAI+D++ L+F +  ++ +    +P    +  S+ C  + LF  TV + SV  +  ++++R   VI P K+R   T + A+  IAGV    L+C + NT
Sbjct:   92 VTCTYILIFMTGVLGNLLTCAVITKDRKMQTPTNLYLFSLAISDLLVLLFGMPLEIYELWQNYPFPFGE--SICCFKIFLFE-TVCFASVLNVTVLSVERYIAVIHPLKTRYAITNKHARRVIAGVWAMSLLCAVPNT 226          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: nmur3 (neuromedin U receptor 3 [Source:ZFIN;Acc:ZDB-GENE-130530-567])

HSP 1 Score: 60.077 bits (144), Expect = 1.792e-9
Identity = 44/138 (31.88%), Postives = 77/138 (55.80%), Query Frame = 2
Query:   83 VVWTFIIVF--GVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGV---CLVCVMINT 481
            V  T+I++F  GV+GN++T  V+         T++YL +LAI+D++ L+F +  ++ +    +P    +  S+ C  + LF  TV + SV  +  ++++R   VI P K+R   T + A+  IAGV    L+C + NT
Sbjct:   60 VTCTYILIFMTGVLGNLLTCAVITKDRKMQTPTNLYLFSLAISDLLVLLFGMPLEIYELWQNYPFPFGE--SICCFKIFLFE-TVCFASVLNVTVLSVERYIAVIHPLKTRYAITNKHARRVIAGVWAMSLLCAVPNT 194          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: galr2a (galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-130603-37])

HSP 1 Score: 56.6102 bits (135), Expect = 1.965e-8
Identity = 55/221 (24.89%), Postives = 103/221 (46.61%), Query Frame = 2
Query:   59 KVIRNICIVVWTFIIVFGVVGNIMTVLVL-QYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTICEWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMII----AKVKHMKNIREKMKTHQHIIK 706
            KV   I  ++++ I + G VGN + + VL +   MNT ST++++  L +AD+ F++F V  Q       + M      +  C  V+   +   Y S++ L  V+LDR   + +P +SR+  T + A ++I+ V  + +  ++ ++     +    +   I  WS V  +    I   IF  ++P L + I     I      V  M+++ E  K  + + K
Sbjct:   15 KVESVIISLIFSMIFLVGTVGNCLVLAVLIRNGQMNTKSTNLFILNLGLADLCFIVFCVPLQAT----IYTMDEWVFGAFVCKAVHFIIYLTMYASIFTLAAVSLDRYLAIRYPLRSRETRTPRNALTSISLVWALSLFFSSPYLSYYQQMDLDGTTVCIPAWS-VHHRQAMDICTFIFGYLIPVLILGITYARTIRYLWTSVDPMQDMSESRKAKRKVTK 230          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: GPR142 (G protein-coupled receptor 142 [Source:HGNC Symbol;Acc:HGNC:20088])

HSP 1 Score: 52.7582 bits (125), Expect = 5.791e-7
Identity = 49/203 (24.14%), Postives = 90/203 (44.33%), Query Frame = 2
Query:   74 ICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSI-YLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTICEWSDV-RFKLIFPIFDLIF-------VNILPSLTMLIANVMIIAKVK 655
            I ++ ++ ++  G+  N++T + L      T  +S  YL AL I+D++  IF +    + F+    +  R+  S   H+V++  F+  + S+W+ V +T+DR   + +P + R F   +  +  I  V L   +    F W                WSDV R      + DLI        +  +P    LI N +II +++
Sbjct:   32 IPVIYYSILLCLGLPVNMLTAVALSRLASRTKKSSYSYLLALTISDILSQIFII---FVGFILQTAILHRKVPSTLIHVVSVLEFSSNHASIWVTVILTVDRYVALCYPLQYRSFSYPERTRRVIVFVFLSSFVTGVPFYW----------------WSDVWRDPRTPGLLDLILKWTHCFIIYFIPCTIFLITNSVIIYRLR 215          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: GALR2 (galanin receptor 2 [Source:NCBI gene;Acc:100486593])

HSP 1 Score: 51.6026 bits (122), Expect = 1.340e-6
Identity = 55/240 (22.92%), Postives = 104/240 (43.33%), Query Frame = 2
Query:   47 PETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQL----IDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVH----------SNKTICE--WSDVRFKLIFPIFDLIFVNILPSLTMLIANVMII----AKVKHMKNIREKMKTHQHIIK 706
            PE+V +      V+++ I + G VGN + + VL        +T++++  L +AD+ F+IF V  Q     +D   F P          C  V+ F +   Y S + L  V+LDR   + +P +SR+   ++T K+ +  + L+         WS+S + S            SN T+C   W D  ++    +    F  ++P L + +     I      V  ++++ E  +  + + +
Sbjct:   15 PESVLIP-----VLYSLIFLVGTVGNSLVLAVLLRNGKVNNTTNLFILNLGVADLCFIIFCVPFQATIYTLDSWVFGPF--------MCKAVHFFIYLTMYASSFTLTTVSLDRYLAIRYPLRSRE---LRTPKNALLAITLI---------WSLSLVFSGPYLSYYQEFQLSNLTVCHPVWQD-SYRRAMDLCTFAFSYVIPVLILSLTYARTIRYLWTAVDPIEDMSESKRAKRRVTR 228          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: nup205 (nucleoporin 205kDa [Source:Xenbase;Acc:XB-GENE-1009711])

HSP 1 Score: 51.6026 bits (122), Expect = 1.503e-6
Identity = 51/216 (23.61%), Postives = 104/216 (48.15%), Query Frame = 2
Query:   83 VVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHS-VFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLIS-VHSNKTIC-EWSDVRFKLIFPIFD--------LIFVNILPSLTMLIANVMIIAKVK-HMKNIREKMKTHQ 694
            V+++ I VFG++GNI+ + V  + +    S  +YL   AIAD++ +I       + F   + +    K   VFC +V    +   YIS+ LL  +++DR   V    +  K   +   K +I   C++ ++     M+ +++  S   SN  +C ++SD + ++   +F+        ++F++++ S   +  N+  I++ + H+ N      T Q
Sbjct:   51 VLYSIIFVFGLLGNILAIYVFLFIHSKRNSVQVYLLNTAIADLLLII------CLPFRIMYHVSQNWKLGIVFCKVVGNLFYMNMYISIVLLGLISMDRYIKVKKSLRRNK---VSDRKCSIQACCVLWIVAVVAVMFLIATQSSKKQSNSNLCFQYSDRKDEIWQAVFNYLLVLVFWIVFLSLILSYVKIAKNLFRISRERAHLPNAGRYSCTAQ 257          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: sp3 (Sp3 transcription factor [Source:Xenbase;Acc:XB-GENE-977158])

HSP 1 Score: 48.9062 bits (115), Expect = 9.080e-6
Identity = 37/128 (28.91%), Postives = 66/128 (51.56%), Query Frame = 2
Query:   83 VVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTS-IYLKALAIADMIFLIFSVGGQ-----LIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIA 448
            V+++ I + G VGN + + VL      T +T+ +++  L++AD+ F+IF V  Q     L D++F          +  C  V+ F +   Y S + L  V++DR   + +P +SR+  T   A +T+A
Sbjct:   31 VIFSLIFLLGTVGNSLVLAVLLRSGQRTHNTTNLFILNLSVADVSFIIFCVPFQATIYSLEDWVF---------GAFMCKAVHFFIYLTMYASSFTLAAVSVDRYLAIRYPLRSRELRTPCNAIATMA 149          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: lmod3 (leiomodin 3 [Source:Xenbase;Acc:XB-GENE-5737414])

HSP 1 Score: 48.9062 bits (115), Expect = 9.168e-6
Identity = 50/202 (24.75%), Postives = 102/202 (50.50%), Query Frame = 2
Query:   44 IPETVKVIRNICI------VVWTFIIVFGVVGN--IMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVT-YISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVM-INTHFMWSVSSLISVHSNKTIC--EWSDVRFKLIFPIFDLIFVNILPSL 613
            +P  VK +  I I      VV+  I   GV+GN  ++TVL    P     +T+I++  L+IAD+ +L+F +  Q    ++  P  +    +  C  ++ F FTV+  +S++ L  +++DR   ++    SR+   ++ +++ + GV ++ ++ I      + +  +   +N+T C   W + + K I+ +   +F  +LP L
Sbjct:   21 VPSAVKPLLGIGIDNVITLVVFGMIFALGVLGNSLVITVLARNKPGKPRSTTNIFILNLSIADLAYLLFCIPFQ--STVYVLPTWVLG--AFICKFIHYF-FTVSMLVSIFTLSAMSVDRYVAIV---HSRRSSAIRVSRNALVGVIVIWILSIAMASPVAYNQGLVYKNNQTFCWESWPNAQQKRIYVVCTFVFGYLLPLL 214          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Cxcr4 (chemokine (C-X-C motif) receptor 4 [Source:MGI Symbol;Acc:MGI:109563])

HSP 1 Score: 51.6026 bits (122), Expect = 6.034e-7
Identity = 54/223 (24.22%), Postives = 103/223 (46.19%), Query Frame = 2
Query:   50 ETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLI---FSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMIN-THFMWSVSSL--ISVHSNKTICE--WSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKN--IREKMKT 688
            E V   R     ++  I + G+VGN + +LV+ Y       T  Y   L++AD++F+I   F     + D+ F             C  V++      Y SV +L F++LDR   ++    S++   +   K+   GV +  +++    F+++  S   IS   ++ IC+  + D  + ++F    ++   +LP + +L    +II+K+ H K    R+ +KT
Sbjct:   32 ENVHFNRIFLPTIYFIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAMADWYF---------GKFLCKAVHIIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKAVYVGVWIPALLLTIPDFIFADVSQGDISQGDDRYICDRLYPDSLWMVVFQFQHIMVGLVLPGIVILSCYCIIISKLSHSKGHQKRKALKT 245          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Cxcr4 (chemokine (C-X-C motif) receptor 4 [Source:MGI Symbol;Acc:MGI:109563])

HSP 1 Score: 51.9878 bits (123), Expect = 8.467e-7
Identity = 54/223 (24.22%), Postives = 103/223 (46.19%), Query Frame = 2
Query:   50 ETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLI---FSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMIN-THFMWSVSSL--ISVHSNKTICE--WSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKN--IREKMKT 688
            E V   R     ++  I + G+VGN + +LV+ Y       T  Y   L++AD++F+I   F     + D+ F             C  V++      Y SV +L F++LDR   ++    S++   +   K+   GV +  +++    F+++  S   IS   ++ IC+  + D  + ++F    ++   +LP + +L    +II+K+ H K    R+ +KT
Sbjct:   34 ENVHFNRIFLPTIYFIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAMADWYF---------GKFLCKAVHIIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKAVYVGVWIPALLLTIPDFIFADVSQGDISQGDDRYICDRLYPDSLWMVVFQFQHIMVGLVLPGIVILSCYCIIISKLSHSKGHQKRKALKT 247          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Sstr4 (somatostatin receptor 4 [Source:MGI Symbol;Acc:MGI:105372])

HSP 1 Score: 48.9062 bits (115), Expect = 7.588e-6
Identity = 50/223 (22.42%), Postives = 95/223 (42.60%), Query Frame = 2
Query:   86 VWTFIIVFGVVGNIMTVLV-LQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKH----SVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTIC--EWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSL 733
            ++  + + G+VGN + + V L+Y  M T +T+IYL  LA+AD +F++          + F       +H    +V C  V        + SV+ L  +++DR   V+ P ++  +     AK    GV L  +++         +  +       C   W    +  +F I+  +   +LP L + +  ++I+ K   M+ +  +    Q    E  I+ L L
Sbjct:   50 IYALVCLVGLVGNALVIFVILRYAKMKT-ATNIYLLNLAVADELFML---------SVPFVASAAALRHWPFGAVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAVFADTRPARGGEAVACNLHWPHPAWSAVFVIYTFLLGFLLPVLAIGLCYLLIVGK---MRAVALRAGWQQRRRSEKKITRLVL 259          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q23497|NPR9_CAEEL (Galanin-like G-protein coupled receptor npr-9 OS=Caenorhabditis elegans OX=6239 GN=npr-9 PE=2 SV=1)

HSP 1 Score: 62.3882 bits (150), Expect = 3.246e-9
Identity = 45/142 (31.69%), Postives = 74/142 (52.11%), Query Frame = 2
Query:   50 ETVKVIRNICIVVWTF---IIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFM---FFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVC 457
            +T+   R I I++ T    II+ G+VGN + V+V     M   ST+  +  LAI+D++FL+  V    +D+    + FP          C ++N F  T  Y SVW L  + LDR   V++P +S    T++T ++T+  +C
Sbjct:   34 DTISFERKIGIIIPTIFAVIILVGLVGNALVVIVAFGRQMRN-STNTLIIGLAISDLMFLLLCVPFTAVDYAAPTWIFPEWT-------CSMINFFQHTSAYCSVWTLTLMALDRYLAVVYPVESM---TLRTPRNTVIALC 164          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|F1R332|GAL2A_DANRE (Galanin receptor 2a OS=Danio rerio OX=7955 GN=galr2a PE=2 SV=2)

HSP 1 Score: 56.6102 bits (135), Expect = 1.484e-7
Identity = 55/221 (24.89%), Postives = 103/221 (46.61%), Query Frame = 2
Query:   59 KVIRNICIVVWTFIIVFGVVGNIMTVLVL-QYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTICEWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMII----AKVKHMKNIREKMKTHQHIIK 706
            KV   I  ++++ I + G VGN + + VL +   MNT ST++++  L +AD+ F++F V  Q       + M      +  C  V+   +   Y S++ L  V+LDR   + +P +SR+  T + A ++I+ V  + +  ++ ++     +    +   I  WS V  +    I   IF  ++P L + I     I      V  M+++ E  K  + + K
Sbjct:   15 KVESVIISLIFSMIFLVGTVGNCLVLAVLIRNGQMNTKSTNLFILNLGLADLCFIVFCVPLQAT----IYTMDEWVFGAFVCKAVHFIIYLTMYASIFTLAAVSLDRYLAIRYPLRSRETRTPRNALTSISLVWALSLFFSSPYLSYYQQMDLDGTTVCIPAWS-VHHRQAMDICTFIFGYLIPVLILGITYARTIRYLWTSVDPMQDMSESRKAKRKVTK 230          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7ZXJ7|CXR4B_XENLA (C-X-C chemokine receptor type 4-B OS=Xenopus laevis OX=8355 GN=cxcr4-b PE=2 SV=1)

HSP 1 Score: 54.299 bits (129), Expect = 1.040e-6
Identity = 56/216 (25.93%), Postives = 104/216 (48.15%), Query Frame = 2
Query:   86 VWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFM---FFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTICE----------WSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKN--IREKMKT 688
            +++FI + G++GN + V+V+ Y   +   T  Y   L++AD++F +F++    +D     +F     +  H ++   VNL      Y SV +L F++LDR   ++    S+    M   K   AGV L  +++    +  V + +S  + + +C+          W+ V F+ +     L    ILP L +L+   +II+K+ H K    R+ +KT
Sbjct:   48 IYSFIFLLGIIGNGLVVVVMGYQKKSRTMTDKYRLHLSVADLLF-VFTLPFWSVDAAIGWYFKEFLCKAVHVIY--TVNL------YSSVLILAFISLDRYLAIVHATNSQGSRKMLADKVVYAGVWLPALLLTVPDL--VFASVSNENGQFVCDRIYPIDNRETWT-VGFRFLHITVGL----ILPGLIILVCYCVIISKLSHSKGHQKRKALKT 247          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8WPA2|AR_BOMMO (Allatostatin-A receptor OS=Bombyx mori OX=7091 GN=AR PE=2 SV=1)

HSP 1 Score: 53.5286 bits (127), Expect = 1.684e-6
Identity = 44/142 (30.99%), Postives = 74/142 (52.11%), Query Frame = 2
Query:   59 KVIRNICIVVWTFIIVFGVVGNIMTVLVLQY-PNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINT 481
            KV+  +  + + FI + G+VGN + VLV+   P M + +T++ +  LA+AD++F+IF V     D++    M        +C +V  F     + SV+ LV ++LDR   V+ P  S    T + A   IA  C+  V++ T
Sbjct:   39 KVVSRVVPIFFGFIGIVGLVGNALVVLVVAANPGMRS-TTNLLIINLAVADLLFVIFCVPFTATDYV----MPRWPFGDWWCKVVQYFIVVTAHASVYTLVLMSLDRFMAVVHPIASMSIRTEKNALLAIA--CIWVVILTT 173          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8SWR3|SPR_DROME (Sex peptide receptor OS=Drosophila melanogaster OX=7227 GN=SPR PE=1 SV=1)

HSP 1 Score: 53.9138 bits (128), Expect = 1.714e-6
Identity = 54/238 (22.69%), Postives = 105/238 (44.12%), Query Frame = 2
Query:   95 FIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMF------FFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVM------INTHFM-----WSVSSLISVHSNKTICEWSDVRFKLIFP---IFDLIFVNILPSLTMLIANVMIIAKVKHMKN-----IREKMKTHQHIIKENVISNLSL 733
            F+++  ++ N + VLVL   +M T  T+  L  +AI DM+ +IF   G    + F        P+ +   +S+F  I+     T   ISVWL + + + R  +V     +R +CTM   +   A + L+  +       +  +M     W+ S     H   ++     +   L +    +F ++FV++LP + ++  N+++ A ++  +       RE  K     ++E   + L L
Sbjct:   98 FLLIITIISNSLIVLVLSKKSMAT-PTNFVLMGMAICDMLTVIFPAPGLWYMYTFGNHYKPLHPVSMCLAYSIFNEIMPAMCHT---ISVWLTLALAVQRYIYVCHAPMARTWCTMPRVRRCTAYIALLAFLHQLPRFFDRTYMPLVIEWNGSPTEVCHLETSMWVHDYIGVDLYYTSYYLFRVLFVHLLPCIILVTLNILLFAAMRQAQERRKLLFRENRKKECKKLRETNCTTLML 331          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A183TNR9 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS18117 PE=4 SV=1)

HSP 1 Score: 248.825 bits (634), Expect = 7.552e-75
Identity = 133/368 (36.14%), Postives = 216/368 (58.70%), Query Frame = 2
Query:   38 EVIPETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVS-SLISVHSNKTICEWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMK----------THQHIIKENVISNLSLENKMNSNLLKPPELVPMNSLSIQKASTSD-KRRDRKTSSLTKMLMTINIFFIISTLPLLIYDLAYWFIDMNLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFRWQALYMVGLC 1105
            E +P    +IR + I VW  I+ FG+ GN++TVLVL+   +   S+  YL  LAI D+++L+ S+   +++++F FP++LRQK +V C I     +T+ YISVWLLV VT++R  WV+ PF +R+ CT  TAK T+    L   + ++HF +++    +S  S   I  +   R   +FP +DL+F  +LP   MLIAN+MI  K++ M+  R  +K          +       + +    +E   + +++   EL P    S Q A+ +  K    K++ LTKML++ N+FFI+S  PLL+YD+ Y+ +D+        ++ G ++F LE +VYTLWY +F++HFLLYC+SGP FR +++ ++  C
Sbjct:   24 EELPLFATIIRFVRIPVWCLILCFGLFGNVLTVLVLRSRKLRQSSSCFYLTVLAITDILYLLTSLLASIVNYIFLFPLELRQKSAVLCVITPFLHYTLAYISVWLLVAVTVERAIWVVLPFSARRICTHLTAKITVTCFILGFTLTDSHFFFTMKYREVSTGSFACIPTYFADR---VFPFYDLLFAALLPCFIMLIANIMIGIKLRSMRKFRSGIKVFSQNGAVETSRMKATCGSTVDEDCVEQPRSGSVIATTELNP----SRQSAAAAPIKGSKEKSTYLTKMLVSTNVFFIVSVTPLLVYDVIYFAVDLRKWAAISEEVRGAVLFALETVVYTLWYTNFAIHFLLYCLSGPPFRLESIALLHRC 384          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A0R3SC23 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS2081 PE=4 SV=1)

HSP 1 Score: 244.973 bits (624), Expect = 1.195e-73
Identity = 135/370 (36.49%), Postives = 213/370 (57.57%), Query Frame = 2
Query:   44 IPETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTICEWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNSNLLKPPELVPMNSLSIQKASTSDKRRDRKTSSLTKMLMTINIFFIISTLPLLIYDLAYWFIDMNLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFRWQALYMVG-LCDKFENTNMKS-RQGN 1147
            IP ++  IR   I +W  ++ FG+ GN +TV VLQ   +   STS YL ALAI DM++L+ S+   + +F +FFP +LRQ    FC ++    +T+ YISVWLLV VT++R  WV+ PF++ + CT +TAK  +  + +V  +++ HF  ++   + +  +K IC  +    K +FP  DL+ V +LP   MLIAN +I  K++ M+  R                 L+    +NSN                 A +++  +  K+++LT+ML++ N+FFIIS  PLLIYD+ ++ ID+    + + K+ G ++FGLE+ VYTLWY +F++HFLLYC+SGP FR + L +   +  +F NT     R+ N
Sbjct:   22 IPLSITAIRYTYIPIWIMLLFFGLFGNALTVFVLQAKRLKQSSTSFYLTALAITDMLYLLTSLVSSIANFTYFFPFELRQTSKTFCVLLPFINYTLAYISVWLLVAVTVERAIWVVLPFRAHRICTRRTAKFIVPLLLIVFTILDIHFFITM-RYVQISKDKWICRPNSFTDK-VFPYLDLLLVAVLPCTVMLIANCLIGWKLRVMRKFRT--------------GTLTGSKTLNSN-----------------ADSTNTEKKEKSTNLTRMLVSTNVFFIISVTPLLIYDVVFFSIDVKAWAEENEKVRGGILFGLERFVYTLWYTNFAIHFLLYCLSGPPFRAEVLVLFNRIRTRFCNTQKNPIREQN 358          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A448XBA4 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Protopolystoma xenopodis OX=117903 GN=PXEA_LOCUS26200 PE=4 SV=1)

HSP 1 Score: 246.899 bits (629), Expect = 1.479e-73
Identity = 140/367 (38.15%), Postives = 217/367 (59.13%), Query Frame = 2
Query:   38 EVIPETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVS---------SLISVHSN--KTICEWSDV-RF-KLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNS-NLLKPPELVPMNSLSIQKASTSDKRRDRKTSSLTKMLMTINIFFIISTLPLLIYDLAYWFIDMNLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFRWQALYMV 1096
            E  P  V+V+R I I VW+ I  FGV+GN  TV+VL+  ++   STS+YL ALA  D+ +L FS+   L    F+FP +LR++H+VFC +     +T+ ++SVWLLV VT+DR FWV+ PF + + CT   A+  I  + L  V ++ H  W++S         +   + SN  +  C+   V RF   +FP  DL+ + ILP +TM  AN++I  K++   + R K +       E ++  +SL +  ++ N L+P               +S+  R  K++ LTKML++ N+FF++S  PLL+YD+ Y   D+   ++ D   +GP++FGLEKLVYTLWY +F++HFLLYC+SG KFR + L ++
Sbjct:   34 EEAPYLVQVMRLILIPVWSGICAFGVLGNCFTVVVLRARHLRQSSTSLYLTALAFVDLAYLCFSLFASLGSLAFWFPSELRRQHAVFCLLQTFLSYTLAFLSVWLLVLVTVDRAFWVLMPFMAYRICTRWHARVAIICLSLGLVGLDLHLFWTMSFQVVLKPTGNQTDLMSNVGRAHCKCVVVSRFTSEVFPYIDLLLIAILPCITMTTANILIGLKLRRQAHFRGKTQAG----GERLLEKMSLGSSTHAQNWLEP------------TGPSSNGPRGEKSAWLTKMLISTNVFFMVSVSPLLVYDILYITEDLVRWVERDEAYWGPVMFGLEKLVYTLWYTNFAIHFLLYCLSGAKFRDEVLRLL 384          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A0R3TQP7 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS9870 PE=4 SV=1)

HSP 1 Score: 244.588 bits (623), Expect = 1.778e-73
Identity = 138/399 (34.59%), Postives = 223/399 (55.89%), Query Frame = 2
Query:   44 IPETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTICEWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNSNLLKPPELVPMNSLSIQKASTSDKRRDRKTSSLTKMLMTINIFFIISTLPLLIYDLAYWFIDMNLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFRWQALYMVGLCDKFENTNMKSRQGNLMNN--NRQMLLPLGASDILSTYRKSLSINH 1234
            IP ++  IR   I +W  ++ FG+ GN +TV VLQ   +   STS YL ALAI DM++L+ S+   + +F++FFP +LRQ    FC ++    +T+ YISVWLLV VT++R  WV+ PF++ + CT +TAK  +  + +V  +++ HF  ++   +++  +K IC+ +    K +FP  DL+ V +LP   MLIAN +I  K++ M   R                  S    +NSN                 A  ++  +  K+++LT+ML++ N+FFIIS  PLLIYD+ ++ ID+    + + K+ G +IFGLE+ VYTLWY +F++HFLLYC+SGP FR +   ++          +++R  N   N   ++  + LGA + +S    + +I  
Sbjct:   22 IPLSITAIRYTYIPIWILLLFFGLFGNALTVFVLQAKRLKQSSTSFYLTALAITDMLYLLTSLVTSVANFIYFFPFELRQTSKTFCVLLPFINYTLAYISVWLLVAVTVERAIWVVLPFRAHRICTRRTAKFVVPLLVIVFTILDIHFFITM-RYVNISKDKWICKPNSFTDK-VFPYLDLLLVAVLPCTIMLIANCLIGWKLRVMLKFRT--------------GTASASKTLNSN-----------------ADPANAEKKEKSTNLTRMLVSTNVFFIISVTPLLIYDVVFFSIDVKAWAEENEKVRGGIIFGLERFVYTLWYTNFAIHFLLYCLSGPPFRAEVFVLLN--------RIRTRFCNAQKNPIRQKTEIKLGAPEKISAVAPTSTIKD 379          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A0R3U400 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS1343 PE=4 SV=1)

HSP 1 Score: 244.588 bits (623), Expect = 2.027e-73
Identity = 140/394 (35.53%), Postives = 215/394 (54.57%), Query Frame = 2
Query:   41 VIPETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTICEWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNSNLLKPPELVPMNSLSIQKASTSDKRRDRKTSSLTKMLMTINIFFIISTLPLLIYDLAYWFIDMNLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFRWQALYMVGLCDKFENTNMKSRQG-NLMNNNRQMLLPLGASDILSTYRKS 1219
            V P  V  IR  CI VW+ ++ FG+ GN +TV VL+   +   STS YL  LAI D+++L+ S+   + +F+FFFP ++RQ  + FC +     +T+ YISVWLLV VT++R  WV+ PF++R  CT +TAK  +  +  V  +++THF  ++   I V  +   C  +    K +FP  DL+FV +LP   MLIAN +I  K++ M+  R                                  V   S S      SDKR   K+++LT+ML++ NIFFI+S  PLLIYD+ ++ +D+    + D  + G ++F +E+LVYTLWY +F++HFLLYC+SGP FR + L +      F       +Q  + +  NR  +    A+++  T R +
Sbjct:   34 VTPPLVSGIRYACIPVWSILLFFGLFGNALTVFVLRAKRLQQSSTSFYLTVLAITDVLYLLTSLVASIANFIFFFPSEVRQISNTFCVLTPFLHYTLAYISVWLLVAVTVERAIWVVLPFQARNICTKRTAKFVVVTIVSVFTLLDTHFFVTM-RYIEVQPSYWSCSTTYFADK-VFPFLDLLFVAVLPCAIMLIANCLIGWKLRVMRKFRSG--------------------------------VAATSTSNNNQGGSDKR--EKSTNLTRMLVSTNIFFIVSVTPLLIYDVVFFSVDVRAWAEEDEDVRGGMLFAIERLVYTLWYTNFAIHFLLYCLSGPPFRAEVLVIFNRLRDFCCCGSAQKQTMDKLEMNRSEIRATSATNVGMTSRDT 391          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: nmur3 (neuromedin-U receptor 2-like [Source:NCBI gene;Acc:103035443])

HSP 1 Score: 58.5362 bits (140), Expect = 5.656e-9
Identity = 45/139 (32.37%), Postives = 82/139 (58.99%), Query Frame = 2
Query:   83 VVWTFIIVF--GVVGNIMT-VLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAG---VCLVCVMINT 481
            V  T+I++F  GV+GN++T ++++++  M T  T++YL +LA++D++ L+F +  ++ +    +P    +  SV C  V LF  TV + SV  +  ++++R   V+ P K+R   T + A+  I G   V LVC + NT
Sbjct:   59 VTLTYILIFITGVLGNLLTCIVIIKHRKMRT-PTNLYLFSLAVSDLLVLLFGMPLEIYELWQNYPFPFGE--SVCCFKVFLFE-TVCFASVLNVTVLSVERYVAVVHPLKTRYALTNKHAQKMIGGVWIVSLVCAVPNT 193          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: trhrb (thyrotropin-releasing hormone receptor-like [Source:NCBI gene;Acc:103029490])

HSP 1 Score: 57.3806 bits (137), Expect = 1.057e-8
Identity = 85/347 (24.50%), Postives = 144/347 (41.50%), Query Frame = 2
Query:   98 IIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGV----CLVCVMINTHFMWSVSSLISVHSNKTICEWSDVRFKLIFPI--FDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNSNLLKPPELVPMNSLSIQKASTSDKRRDRKTSSLTKMLMTINIFFIISTLP---LLIYD--LAYWFIDMNLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFRW-QALYMVGL 1102
            I   G+VGN+M +LV+         T+ YL +LA AD++ L+ +    + D ++   +  R    V C  +  F +     S   +   T++R   +  P +++  CT   AK  I GV     L CVM    ++  +  L+   +    C +   R  L  PI  FD     +LP LT+      +IA++  +  + +    + H   + V S     NK N           + S S   ++T+  RR      +TKML  + I F +  +P   L++ +  L   ++D   L+     +Y  L   +  ++Y      F   F   C  GP+ +  QA Y V L
Sbjct:   32 ICALGIVGNVMVILVVLTTKHMRTPTNCYLVSLAAADLMVLVAAGLPSVADSLYGSWLFGR----VGCLCITYFQYLGINASSCSITAFTVERYIAICHPIRAQSLCTYTRAKRIILGVWVTTSLYCVMW--FYLADIEELVYEDATIVSCAYKVSR-NLYLPIYFFDFGVFFVLP-LTLSTVLYGLIARILFLNPLPKTKSKNGH---DGVYSG----NKTNG----------LKSSSQCSSTTAASRRQ-----VTKMLAVVVILFAVLWMPYRTLVVVNSFLQEAYLDTWFLLFCRTCVY--LNSAINPVIYNAMSQKFRAAFKRLCRCGPRVQAKQAAYSVAL 346          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: CCKBR (cholecystokinin receptor-like [Source:NCBI gene;Acc:103038142])

HSP 1 Score: 53.5286 bits (127), Expect = 2.032e-7
Identity = 83/377 (22.02%), Postives = 160/377 (42.44%), Query Frame = 2
Query:   47 PETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFS-----VGGQLIDFMFFFPMQLRQKHSVFCHIVN-LFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLIS-VHSNKTIC------EWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNSN----LLKPPELVPMNSLSIQKASTSDKRRDRKTSS-------LTKMLMTINIFFIISTLPLLIYDLAYWFIDMNLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFRWQALYMVGLC 1105
            P+ +  +R   I++++ I +  V GN++ ++VL         T+ +L +LA++D++  +F      +   L DF+F          +  C IV  L G +V+ IS + L+ + ++R   +  P KSR + T   A   IA   +   +I T +   VS+L++    N TI       +W   + +  + I  L  +  +P + M+ A  +I  ++        + K  Q  IK    + +S  N         + K P  + M++L++  ++  D+ R   + +       + +ML+ I   F I  +PL   +    F   +      G    P+ F     ++ L Y    ++ ++YC    +FR   L     C
Sbjct:   45 PKEMDSVR---ILLYSLIFLLSVFGNLLIIVVLLVNKRMRTVTNSFLLSLAVSDLMMAVFCMPFTFIPNLLEDFIF---------GAAMCKIVAYLMGISVS-ISTFSLMAIAIERYSAICNPLKSRAWQTRSHAYKVIAVTWVASFLIMTPYPI-VSTLVNYTKPNNTITRHMCRHDWPKDQVQQAWCILLLFVLFFIPGVVMITAYGLISRELYRGIQFELEQKKGQCGIKNGASTPVSTGNDDGDGCYIQVSKRPNSMEMSTLTLTSSAKVDRPRSNTSETKLMAKKRVIRMLIVIVTMFFICWMPLYSANTWRAFHPASAHRLLSG---APISF-----IHLLSYTSACVNPIIYCFMNKRFRKALLTTFSCC 399          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: zgc:172079 (zgc:172079 [Source:ZFIN;Acc:ZDB-GENE-080204-103])

HSP 1 Score: 51.2174 bits (121), Expect = 9.678e-7
Identity = 37/127 (29.13%), Postives = 63/127 (49.61%), Query Frame = 2
Query:   80 IVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCL 460
            +VV++ + + G++ N+M ++V      +   T++Y+  LA+AD+ FL+ ++  ++    F  P Q        C I  L      Y S++LL  V LDR   V FP  SR    +Q A+     VC+
Sbjct:   13 VVVYSLVFIAGLILNLMAIVVFFCQTKSRSHTTVYMTNLAVADL-FLVCTLPFRIYYHSFKSPAQR------ICDIAGLILLANMYGSIFLLTCVCLDRCLAVCFPMSSR----IQEARKKAPLVCV 128          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: si:ch73-160i9.3 (C3a anaphylatoxin chemotactic receptor-like [Source:NCBI gene;Acc:103032193])

HSP 1 Score: 49.2914 bits (116), Expect = 4.283e-6
Identity = 40/144 (27.78%), Postives = 75/144 (52.08%), Query Frame = 2
Query:   62 VIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFF--FPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHF 487
            ++ NI IV++T  I+ G+ GN + + +  +  +    T+++L  LA+AD+IF +  V   LI  +F+  +P  L       C     F +   + SV+LL  ++LDR   V  P  +R+  T++ A+    GV +V  + ++ +
Sbjct:   31 IMDNITIVLYTITIILGITGNSVVIWMAGFC-LKANVTNVWLVNLAVADLIFCLTRV-TSLIKKLFYDHWPFGL-----FLCKFNGFFKYANMFCSVFLLAVISLDRAICVWLPVFTRQRRTVRAARLVSLGVWIVAGLFSSPY 167          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Match: nmur1a (neuromedin U receptor 1a [Source:ZFIN;Acc:ZDB-GENE-081104-220])

HSP 1 Score: 51.2174 bits (121), Expect = 1.883e-7
Identity = 50/209 (23.92%), Postives = 100/209 (47.85%), Query Frame = 2
Query:   80 IVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTI-----AGVCLVCVMINT-----HFMWSVSSLISVHSNKTICEWSDVR--FKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNI 670
            + ++  I V GVVGN +T +V+    +    T+ YL +LA++D++ L+  +  +L +    +P    +     C+   +   TV + SV  +  ++++R   V+ P K+R   T   A+  I     A VC  C + NT     H++   S L   +   TIC  +  R  + ++  +  L F  ++P  T+ +  ++I  +++  K++
Sbjct:   57 LAIYLLIFVTGVVGNFLTCIVISRHRLMRTPTNFYLFSLAVSDLLVLVLGMPLELYEMWENYPSLFGEGG---CYFKTMLFETVCFASVLNVTALSVERYIAVVHPLKARWLVTRTHARRVIACLWVASVC--CSVPNTSLHGIHYI--RSPLGEPYEESTICIVTQPRWIYNVVVQLTALFFF-LVPMATISVLYLLIGRQLRREKSL 257          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: si:ch73-160i9.1 (C3a anaphylatoxin chemotactic receptor [Source:NCBI gene;Acc:101158210])

HSP 1 Score: 52.373 bits (124), Expect = 4.747e-7
Identity = 41/135 (30.37%), Postives = 70/135 (51.85%), Query Frame = 2
Query:   62 VIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFF--FPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCL 460
            ++ NI I+++T  +V G+ GN + + V  +  +    T+++L  LAIAD+IF  F+    LI  +FF  +P  +       C     F +   + SV+LL  ++LDRM  +  P   R+   M TA+  +  VC+
Sbjct:   27 IMENISIILYTLTVVLGITGNSVVIWVAGF-KLKPKVTNVWLVNLAIADLIF-CFTRVFSLIKKLFFDHWPFGV-----FLCKFNGFFKYANMFCSVFLLAVISLDRMLCIWHPIFMRRHHKMWTAR--VVAVCV 152          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: si:ch73-160i9.1 (C3a anaphylatoxin chemotactic receptor [Source:NCBI gene;Acc:101158210])

HSP 1 Score: 51.9878 bits (123), Expect = 6.135e-7
Identity = 41/135 (30.37%), Postives = 70/135 (51.85%), Query Frame = 2
Query:   62 VIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFF--FPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCL 460
            ++ NI I+++T  +V G+ GN + + V  +  +    T+++L  LAIAD+IF  F+    LI  +FF  +P  +       C     F +   + SV+LL  ++LDRM  +  P   R+   M TA+  +  VC+
Sbjct:   41 IMENISIILYTLTVVLGITGNSVVIWVAGF-KLKPKVTNVWLVNLAIADLIF-CFTRVFSLIKKLFFDHWPFGV-----FLCKFNGFFKYANMFCSVFLLAVISLDRMLCIWHPIFMRRHHKMWTAR--VVAVCV 166          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000022492.2 (cholecystokinin receptor-like [Source:NCBI gene;Acc:101161683])

HSP 1 Score: 49.6766 bits (117), Expect = 4.271e-6
Identity = 77/366 (21.04%), Postives = 159/366 (43.44%), Query Frame = 2
Query:   80 IVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLI-----DFMFFFPMQLRQKHSVFCHIVN-LFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHF-----MWSVSSLISVHSNKTICEWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKE---NVISNLSLE-NKMNSNLLKPPELVPMNSLSIQ---------KASTSDKRRDRKTSSLTKMLMTINIFFIISTLPLLIYDLAYWFIDMNLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFRWQALYMVGLC 1105
            I++++ I    V GN++ ++VL         T+ +L +LA++D++  IF +   LI     DF+F   M         C IV+ L G +V+ IS + LV + ++R   +  P KSR + T   A   IA   ++  +I   +     +       +  ++K   +W     +  + +  L+ +  +P + M+IA  +I  ++          K     +K    + +SN+S + +     +++ P  + M++++           +++TS+ + + K   + +ML+ I + F +  +PL   +    F D +      G    P+ F     ++ L Y    ++ ++YC    +FR   L     C
Sbjct:   63 ILLYSLIFFLSVFGNLLIIVVLTVNKRMRTVTNTFLLSLAVSDLMMAIFCMPFTLIPNILKDFIFGAAM---------CKIVSYLMGISVS-ISTFSLVAIAIERYSAICNPLKSRVWQTRSHAYRVIAATWVLAFIIMVPYPIISHLEPFQGSANTTAHKCRHKWPIQTAEQTWYVMLLLILFAIPGVVMIIAYGLISRELYRGIRFEMGQKKDSTDVKNGLTSTVSNVSDDGDGCYVTVVQRPHSMEMSTMAASIRQVKADRPRSNTSEAKLEAK-KRVIRMLVVIVVLFFLCWMPLYCVNTWRAFDDSSATRALSG---APIAF-----IHLLSYTSACVNPIIYCFMNTRFRKALLSTFSWC 409          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: ghsrb (growth hormone secretagogue receptor type 1 [Source:NCBI gene;Acc:101167158])

HSP 1 Score: 49.2914 bits (116), Expect = 4.604e-6
Identity = 37/142 (26.06%), Postives = 74/142 (52.11%), Query Frame = 2
Query:   83 VVWTFIIVFGVVGNIMTVLVL-QYPNMNTMSTSIYLKALAIAD-MIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVS 502
            V  T + + GV GN+MT+LV+ +Y +M T +T++YL ++A++D +IFL   +   L     + P +L       C +      + TY ++  +  ++++R   + FP +++   T +  ++      L+C      F+W+VS
Sbjct:   72 VACTLLFLVGVTGNVMTILVVGRYRDMRT-TTNLYLCSMAVSDLLIFLCMPL--DLYRMWRYRPWRL---GDALCKLFQFVSESCTYSTILSITALSVERYLAICFPLRAKALVTKRRVRA------LIC------FLWTVS 195          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: trhr2 (TRHR2 protein [Source:NCBI gene;Acc:100533510])

HSP 1 Score: 49.2914 bits (116), Expect = 4.610e-6
Identity = 64/275 (23.27%), Postives = 114/275 (41.45%), Query Frame = 2
Query:  110 GVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFS----VGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGV----CLVCVMINTHFMWSVSSLISVHSNKTICEWSDVRFKLIFPIF--DLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNSNLLKPP-ELVPMNSLSIQKASTSDKRRDRKTSSLTKMLMTINIFFIISTLP 901
            G++GN+M VLV+         T+ YL +LAIAD+  L+ +    V   L     F      Q   +    +   G  V+  S+      T++R   +  P K++  CT+  AK  IAGV    C+ C+      +W     I V  +  +     V+ +L  PI+  D     ++P L + I    +IA++ ++  +  +  T    ++ +         +  S   +P  +  P ++LS +K              +TKML  + I F +  +P
Sbjct:   36 GIIGNVMVVLVVFTTRHMRTPTNCYLVSLAIADLTVLVAAGLPNVSDSLTGTWIF-----GQAGCLGITYLQYLGINVSSCSITAF---TVERYIAICHPMKAQTVCTVSRAKRIIAGVWIFTCVYCM------LWLFLVDIQVGPDGHVQCGYRVKRELYLPIYLIDFAIFYVIP-LLLAIVLYALIARILYLSPLPHQPDTSATTLRRSC--------RDTSEAARPGRQGRPKSALSSRK-------------QVTKMLAVVVILFALLWMP 274          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000000903.1 (SMESG000000903.1)

HSP 1 Score: 819.305 bits (2115), Expect = 0.000e+0
Identity = 401/402 (99.75%), Postives = 402/402 (100.00%), Query Frame = 2
Query:   35 MEVIPETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTICEWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNSNLLKPPELVPMNSLSIQKASTSDKRRDRKTSSLTKMLMTINIFFIISTLPLLIYDLAYWFIDMNLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFRWQALYMVGLCDKFENTNMKSRQGNLMNNNRQMLLPLGASDILSTYRKSLSINHRN 1240
            MEVIPETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCT+QTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTICEWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNSNLLKPPELVPMNSLSIQKASTSDKRRDRKTSSLTKMLMTINIFFIISTLPLLIYDLAYWFIDMNLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFRWQALYMVGLCDKFENTNMKSRQGNLMNNNRQMLLPLGASDILSTYRKSLSINHRN
Sbjct:    1 MEVIPETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTIQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTICEWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNSNLLKPPELVPMNSLSIQKASTSDKRRDRKTSSLTKMLMTINIFFIISTLPLLIYDLAYWFIDMNLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFRWQALYMVGLCDKFENTNMKSRQGNLMNNNRQMLLPLGASDILSTYRKSLSINHRN 402          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000037421.1 (SMESG000037421.1)

HSP 1 Score: 308.916 bits (790), Expect = 2.312e-101
Identity = 169/395 (42.78%), Postives = 252/395 (63.80%), Query Frame = 2
Query:   41 VIPETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTICEWSD-VRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNSNLLKPPELV-PMNSLSIQKASTSD------KRR-------DRKTSSLTKMLMTINIFFIISTLPLLIYDLAYWFIDMNLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFRWQALYMVGLC----DKFENTNMKSRQGNLMNNNRQ 1168
            V+P++V++IR ICI VW  II+ GV GNI+TV+VL  P +NT ST+ YL  LAI D+++LIFS+GGQ++DF   FP  +RQ + + C ++N+  +T+ YISVWLLV V++DRM WV+ PFK++  CT + AK  ++  C+  + I+ HF+W+V  +   H  K  CE  D + FK IFP  DL  + ILP + MLI+N++I+ K++ +  +R+ +     I + N +  L +  KMNS +  P       N +SI   + S+      KRR       D++T+SLT+ML+++N+FF+ ST PLLIYD+ Y+ ID   +I+  G   G +IFG+E+LVYT WYL+FS+HFLLYC+SGPKFR +A   +         F  +++KS   NL  NN +
Sbjct:   14 VMPDSVEIIRRICIAVWANIILVGVFGNILTVIVLAGPKLNTTSTTFYLTILAIVDLLYLIFSLGGQMVDFALLFPNTMRQSNELSCKLLNIILYTLAYISVWLLVAVSIDRMIWVLLPFKAKLICTRKVAKIIVSIFCIFFIGIDIHFIWTVKFV--KHQTKNNCEVIDNILFKYIFPYVDLTLIMILPFVIMLISNILIVLKIQKVSVLRQTLHRSSTIPEPNQVGILKV--KMNS-ISSPSRFQDDTNQISISSRNRSESQVKFFKRRQSKYSLKDKQTTSLTRMLLSVNLFFMASTAPLLIYDVIYYLIDFKEMIQKYGIYIGGVIFGVERLVYTFWYLNFSIHFLLYCLSGPKFREEAKLFISQYFFRRKSFNQSSVKS-VNNLKQNNTK 402          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000002498.1 (SMESG000002498.1)

HSP 1 Score: 295.049 bits (754), Expect = 6.088e-96
Identity = 153/354 (43.22%), Postives = 238/354 (67.23%), Query Frame = 2
Query:   38 EVIPETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTICEWSDVRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNSNLLKPPELVPMNSLSIQKASTSDKRRDRKTSSLTKMLMTINIFFIISTLPLLIYDLAYWFIDM-NLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFRWQALYMV 1096
            ++ P  + +IRNICI VW  I++FG+ GN +TV VL  P +N  ST+ YL  LA+ D+++LIFS+GGQ+++F  FFP  LRQK+   C  +++  FT+TYISVWLLV V +DRM WVIFPFK++  CT + AK  +  +  + V+I+ HF W++    +  S  + CE  +  ++  F   DL  V  LP   M +AN +II+K++ M+ +R+ MK+   I  ++VI NL+  +K ++        V   +  I K ST  + RD++T+SLTKML+++NIFF++ST PLL Y++ ++   + +LL++ + +L G LIFG+E+++YTLWYL+F++HFLLYCMSGPKFR +A+ ++
Sbjct:   13 QIHPPAIDIIRNICIGVWAIIVLFGLFGNCLTVAVLISPKLNNSSTTFYLTVLALIDILYLIFSLGGQMLNFSIFFPAALRQKNMFACISLSMIRFTLTYISVWLLVAVAIDRMIWVIFPFKAKMICTRKIAKIIVISLIAMLVLIDLHFYWTLKFTYNKGSVNS-CELKE-SYRNPFLYIDLTLVMGLPFFVMSVANSLIISKLREMEKLRKGMKSTNRIPNDSVIPNLNATSKFSNRKHAKNNNVEEITCEIVKRSTRRRSRDKQTTSLTKMLLSVNIFFLVSTTPLLSYNILFYVPHIKSLLLQFENQLTG-LIFGIERIIYTLWYLNFAVHFLLYCMSGPKFRQEAIRLL 363          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000047150.1 (SMESG000047150.1)

HSP 1 Score: 264.618 bits (675), Expect = 2.387e-85
Identity = 144/339 (42.48%), Postives = 218/339 (64.31%), Query Frame = 2
Query:   41 VIPETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTICEWSD-VRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNSNLLKPPELV-PMNSLSIQKASTSD------KRR-------DRKTSSLTKMLMTINIFFIISTLPLLIYDLAYWFIDMNLLIKTDGKLYGPLIFGLEKLVYT 1012
            V+P++V++IR ICI VW  II+ GV GNI+TV+VL  P +NT ST+ YL  LAI D+++LIFS+GGQ++DF   FP  +RQ + + C ++N+  +T+ YISVWLLV V++DRM WV+ PFK++  CT + AK  ++  C+  + I+ HF+W+V  +   H  K  CE  D + FK IFP  DL  + ILP + MLI+N++I+ K++ +  +R+ +     I + N +  L +  KMNS +  P       N +SI   + S+      KRR       D++T+SLT+ML+++N+FF+ ST PLLIYD+ Y+ ID   +I+  G   G +IFG+E+LVYT
Sbjct:   14 VMPDSVEIIRRICIAVWANIILVGVFGNILTVIVLAGPKLNTTSTTFYLTILAIVDLLYLIFSLGGQMVDFALLFPNTMRQSNELSCKLLNIILYTLAYISVWLLVAVSIDRMIWVLLPFKAKLICTRKVAKIIVSIFCIFFIGIDIHFIWTVKFV--KHQTKNNCEVIDNILFKYIFPYVDLTLIMILPFVIMLISNILIVLKIQKVSVLRQTLHRSSTIPEPNQVGILKV--KMNS-ISSPSRFQDDTNQISISSRNRSESQVKFFKRRQSKYSLKDKQTTSLTRMLLSVNLFFMASTAPLLIYDVIYYLIDFKEMIQKYGIYIGGVIFGVERLVYT 347          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000047150.1 (SMESG000047150.1)

HSP 1 Score: 244.973 bits (624), Expect = 5.430e-78
Identity = 134/320 (41.88%), Postives = 205/320 (64.06%), Query Frame = 2
Query:   41 VIPETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIYLKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVTYISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTHFMWSVSSLISVHSNKTICEWSD-VRFKLIFPIFDLIFVNILPSLTMLIANVMIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNSNLLKPPELV-PMNSLSIQKASTSD------KRR-------DRKTSSLTKMLMTINIFFIISTLPLLIYDLAYWFIDMNLLIK 955
            V+P++V++IR ICI VW  II+ GV GNI+TV+VL  P +NT ST+ YL  LAI D+++LIFS+GGQ++DF   FP  +RQ + + C ++N+  +T+ YISVWLLV V++DRM WV+ PFK++  CT + AK  ++  C+  + I+ HF+W+V  +   H  K  CE  D + FK IFP  DL  + ILP + MLI+N++I+ K++ +  +R+ +     I + N +  L +  KMNS +  P       N +SI   + S+      KRR       D++T+SLT+ML+++N+FF+ ST PLLIYD+ Y+ ID   +I+
Sbjct:   14 VMPDSVEIIRRICIAVWANIILVGVFGNILTVIVLAGPKLNTTSTTFYLTILAIVDLLYLIFSLGGQMVDFALLFPNTMRQSNELSCKLLNIILYTLAYISVWLLVAVSIDRMIWVLLPFKAKLICTRKVAKIIVSIFCIFFIGIDIHFIWTVKFV--KHQTKNNCEVIDNILFKYIFPYVDLTLIMILPFVIMLISNILIVLKIQKVSVLRQTLHRSSTIPEPNQVGILKV--KMNS-ISSPSRFQDDTNQISISSRNRSESQVKFFKRRQSKYSLKDKQTTSLTRMLLSVNLFFMASTAPLLIYDVIYYLIDFKEMIQ 328          
The following BLAST results are available for this feature:
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
SSTR44.097e-620.74somatostatin receptor 4 [Source:HGNC Symbol;Acc:HG... [more]
CCR16.091e-628.29C-C motif chemokine receptor 1 [Source:HGNC Symbol... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
npr-92.552e-1031.69Galanin-like G-protein coupled receptor npr-9 [So... [more]
frpr-91.154e-825.60FMRFamide Peptide Receptor family [Source:UniProt... [more]
frpr-97.715e-823.84FMRFamide Peptide Receptor family [Source:UniProt... [more]
trhr-11.797e-722.58Thyrotropin-Releasing Hormone Receptor [Source:Un... [more]
Y70D2A.13.808e-725.00pep chromosome:WBcel235:X:14918836:14923942:1 gene... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CNMaR1.410e-1622.13gene:FBgn0053696 transcript:FBtr0091684[more]
Proc-R1.593e-932.56gene:FBgn0029723 transcript:FBtr0100552[more]
Proc-R1.593e-932.56gene:FBgn0029723 transcript:FBtr0070713[more]
Proc-R1.593e-932.56gene:FBgn0029723 transcript:FBtr0100551[more]
Proc-R1.593e-932.56gene:FBgn0029723 transcript:FBtr0070714[more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-1h24.27.035e-1021.68si:dkey-1h24.2 [Source:ZFIN;Acc:ZDB-GENE-060503-48... [more]
si:dkey-1h24.27.460e-1022.65si:dkey-1h24.2 [Source:ZFIN;Acc:ZDB-GENE-060503-48... [more]
nmur31.626e-931.88neuromedin U receptor 3 [Source:ZFIN;Acc:ZDB-GENE-... [more]
nmur31.792e-931.88neuromedin U receptor 3 [Source:ZFIN;Acc:ZDB-GENE-... [more]
galr2a1.965e-824.89galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-1306... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GPR1425.791e-724.14G protein-coupled receptor 142 [Source:HGNC Symbol... [more]
GALR21.340e-622.92galanin receptor 2 [Source:NCBI gene;Acc:100486593... [more]
nup2051.503e-623.61nucleoporin 205kDa [Source:Xenbase;Acc:XB-GENE-100... [more]
sp39.080e-628.91Sp3 transcription factor [Source:Xenbase;Acc:XB-GE... [more]
lmod39.168e-624.75leiomodin 3 [Source:Xenbase;Acc:XB-GENE-5737414][more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Cxcr46.034e-724.22chemokine (C-X-C motif) receptor 4 [Source:MGI Sym... [more]
Cxcr48.467e-724.22chemokine (C-X-C motif) receptor 4 [Source:MGI Sym... [more]
Sstr47.588e-622.42somatostatin receptor 4 [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q23497|NPR9_CAEEL3.246e-931.69Galanin-like G-protein coupled receptor npr-9 OS=C... [more]
sp|F1R332|GAL2A_DANRE1.484e-724.89Galanin receptor 2a OS=Danio rerio OX=7955 GN=galr... [more]
sp|Q7ZXJ7|CXR4B_XENLA1.040e-625.93C-X-C chemokine receptor type 4-B OS=Xenopus laevi... [more]
sp|Q8WPA2|AR_BOMMO1.684e-630.99Allatostatin-A receptor OS=Bombyx mori OX=7091 GN=... [more]
sp|Q8SWR3|SPR_DROME1.714e-622.69Sex peptide receptor OS=Drosophila melanogaster OX... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A183TNR97.552e-7536.14G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
A0A0R3SC231.195e-7336.49G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
A0A448XBA41.479e-7338.15G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
A0A0R3TQP71.778e-7334.59G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
A0A0R3U4002.027e-7335.53G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nmur35.656e-932.37neuromedin-U receptor 2-like [Source:NCBI gene;Acc... [more]
trhrb1.057e-824.50thyrotropin-releasing hormone receptor-like [Sourc... [more]
CCKBR2.032e-722.02cholecystokinin receptor-like [Source:NCBI gene;Ac... [more]
zgc:1720799.678e-729.13zgc:172079 [Source:ZFIN;Acc:ZDB-GENE-080204-103][more]
si:ch73-160i9.34.283e-627.78C3a anaphylatoxin chemotactic receptor-like [Sourc... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
nmur1a1.883e-723.92neuromedin U receptor 1a [Source:ZFIN;Acc:ZDB-GENE... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:ch73-160i9.14.747e-730.37C3a anaphylatoxin chemotactic receptor [Source:NCB... [more]
si:ch73-160i9.16.135e-730.37C3a anaphylatoxin chemotactic receptor [Source:NCB... [more]
ENSORLT00000022492.24.271e-621.04cholecystokinin receptor-like [Source:NCBI gene;Ac... [more]
ghsrb4.604e-626.06growth hormone secretagogue receptor type 1 [Sourc... [more]
trhr24.610e-623.27TRHR2 protein [Source:NCBI gene;Acc:100533510][more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000000903.10.000e+099.75SMESG000000903.1[more]
SMESG000037421.12.312e-10142.78SMESG000037421.1[more]
SMESG000002498.16.088e-9643.22SMESG000002498.1[more]
SMESG000047150.12.387e-8542.48SMESG000047150.1[more]
SMESG000047150.15.430e-7841.88SMESG000047150.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010212 ID=SMED30010212|Name=G_PROTEIN_RECEP_F1_2 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1259bp
CTACCAATTTCTCAAACGGAAAACAAGAATATAAATGGAAGTTATTCCTG
AAACCGTGAAAGTTATTCGAAACATTTGTATTGTAGTTTGGACGTTCATT
ATCGTATTCGGAGTCGTGGGGAATATTATGACCGTTTTAGTTTTGCAGTA
TCCGAACATGAATACAATGAGCACATCCATATATCTGAAAGCCCTGGCGA
TTGCTGACATGATTTTCCTGATTTTCAGCGTCGGTGGTCAGCTAATTGAC
TTCATGTTCTTTTTTCCAATGCAGTTGCGCCAGAAACATTCGGTATTTTG
TCACATTGTCAACTTGTTCGGTTTCACCGTGACCTATATTAGTGTTTGGC
TATTGGTTTTTGTTACACTCGATCGGATGTTTTGGGTGATTTTTCCATTT
AAATCGAGAAAATTCTGCACAATGCAAACTGCAAAATCAACAATTGCAGG
AGTTTGTTTGGTCTGTGTGATGATCAATACGCACTTTATGTGGAGTGTTT
CTTCATTGATTTCGGTTCATTCAAACAAAACGATTTGTGAATGGTCAGAC
GTAAGGTTTAAACTGATCTTTCCGATTTTCGACTTGATATTTGTCAATAT
CCTTCCATCTTTGACAATGTTGATAGCCAACGTGATGATCATTGCAAAAG
TGAAACACATGAAAAATATTCGAGAGAAAATGAAAACTCACCAACACATC
ATCAAAGAGAATGTAATTTCAAACCTTTCTTTGGAAAATAAAATGAACTC
CAATTTATTGAAACCTCCTGAACTCGTACCAATGAACTCCCTGTCCATTC
AGAAAGCTTCGACTTCAGACAAACGTCGAGATCGTAAAACTTCAAGCCTT
ACGAAAATGTTGATGACAATTAACATATTTTTTATAATTTCAACTTTACC
GCTTTTGATTTATGATCTCGCTTATTGGTTCATTGATATGAATTTATTAA
TTAAAACGGATGGGAAATTATATGGACCATTGATATTCGGATTGGAGAAA
TTGGTTTACACGTTGTGGTATTTACATTTCTCGATGCACTTCCTGCTTTA
TTGCATGAGTGGACCAAAGTTCCGGTGGCAAGCACTTTACATGGTAGGGT
TGTGCGATAAATTTGAAAACACAAATATGAAAAGTCGACAAGGAAACTTA
ATGAACAACAATCGACAGATGCTTTTACCTCTCGGAGCGTCTGATATTTT
GTCGACCTACAGGAAAAGTCTGAGTATAAATCATCGAAATTAAATATTTT
TCTTTTTAC
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protein sequence of SMED30010212-orf-1

>SMED30010212-orf-1 ID=SMED30010212-orf-1|Name=SMED30010212-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=403bp
MEVIPETVKVIRNICIVVWTFIIVFGVVGNIMTVLVLQYPNMNTMSTSIY
LKALAIADMIFLIFSVGGQLIDFMFFFPMQLRQKHSVFCHIVNLFGFTVT
YISVWLLVFVTLDRMFWVIFPFKSRKFCTMQTAKSTIAGVCLVCVMINTH
FMWSVSSLISVHSNKTICEWSDVRFKLIFPIFDLIFVNILPSLTMLIANV
MIIAKVKHMKNIREKMKTHQHIIKENVISNLSLENKMNSNLLKPPELVPM
NSLSIQKASTSDKRRDRKTSSLTKMLMTINIFFIISTLPLLIYDLAYWFI
DMNLLIKTDGKLYGPLIFGLEKLVYTLWYLHFSMHFLLYCMSGPKFRWQA
LYMVGLCDKFENTNMKSRQGNLMNNNRQMLLPLGASDILSTYRKSLSINH
RN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR000276GPCR_Rhodpsn
IPR017452GPCR_Rhodpsn_7TM
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
Vocabulary: molecular function
TermDefinition
GO:0004930G-protein coupled receptor activity
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000276G protein-coupled receptor, rhodopsin-likePRINTSPR00237GPCRRHODOPSNcoord: 180..203
score: 18.44
coord: 321..347
score: 20.37
coord: 14..38
score: 22.31
coord: 47..68
score: 27.44
coord: 96..118
score: 21.79
coord: 272..296
score: 22.03
IPR000276G protein-coupled receptor, rhodopsin-likePFAMPF000017tm_1coord: 29..299
e-value: 3.1E-19
score: 69.3
NoneNo IPR availablePANTHERPTHR46641FAMILY NOT NAMEDcoord: 14..371
NoneNo IPR availablePANTHERPTHR46641:SF12CNMAMIDE RECEPTORcoord: 14..371
NoneNo IPR availableCDDcd149787tmA_FMRFamide_R-likecoord: 14..347
e-value: 1.20607E-32
score: 122.742
NoneNo IPR availableSUPERFAMILYSSF81321Family A G protein-coupled receptor-likecoord: 10..372
NoneNo IPR availableTMHMMTMhelixcoord: 49..71
NoneNo IPR availableTMHMMTMhelixcoord: 275..297
NoneNo IPR availableTMHMMTMhelixcoord: 15..37
NoneNo IPR availableTMHMMTMhelixcoord: 317..339
NoneNo IPR availableTMHMMTMhelixcoord: 181..203
NoneNo IPR availableTMHMMTMhelixcoord: 91..112
NoneNo IPR availableTMHMMTMhelixcoord: 133..155
IPR017452GPCR, rhodopsin-like, 7TMPROSITEPS50262G_PROTEIN_RECEP_F1_2coord: 29..339
score: 24.323