Malate dehydrogenase

Overview
NameMalate dehydrogenase
Smed IDSMED30010208
Length (bp)1099
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Malate dehydrogenase (SMED30010208) t-SNE clustered cells

Violin plots show distribution of expression levels for Malate dehydrogenase (SMED30010208) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Malate dehydrogenase (SMED30010208) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Malate dehydrogenase (SMED30010208) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30010208

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30010208h1SMcG0020177 SmedASXL_003769SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30010208h1SMcG0020177 Contig29363uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30010208h1SMcG0020177 Contig29363newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30010208h1SMcG0020177 dd_Smed_v4_1954_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30010208h1SMcG0020177 dd_Smed_v4_1954_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30010208h1SMcG0020177 dd_Smed_v4_1954_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30010208h1SMcG0020177 dd_Smed_v4_1954_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30010208h1SMcG0020177 dd_Smed_v4_1954_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30010208h1SMcG0020177 dd_Smed_v4_1954_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Human
Match: MDH2 (malate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:6971])

HSP 1 Score: 361.688 bits (927), Expect = 6.898e-124
Identity = 165/327 (50.46%), Postives = 233/327 (71.25%), Query Frame = 2 
Query:   77 SVLFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKS 1057
            S   R S  +      KV+VLGA+GGIGQPL L  K +PL+  L LYDI +  GVA DLSHIE K  V  + G E+L  CL   D+VVIPAG+PR PGM+R+DLF +NA I+A LT + A+HCP A+IC+I NP+NS +P+ AE+     V++  K+FG+TTL  +RA TF+A+ K +D  +++VPVIGGH+G TIIP+ISQ  P V FP ++   +  +I+ AG+E+V+AKAG GSATLSM++A  RF+ SL++A  G+ GV+E ++VKS ETEC YF++ LL G++G+E+NLGIG+++ FE  ++  AIP +K  I+ G+ + K+
Sbjct:   10 SAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKT 336
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Human
Match: MDH2 (malate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:6971])

HSP 1 Score: 300.056 bits (767), Expect = 3.240e-100
Identity = 147/327 (44.95%), Postives = 204/327 (62.39%), Query Frame = 2 
Query:   77 SVLFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKS 1057
            S   R S  +      KV+VLGA+GGIGQPL L  K +PL+  L LYDI +  GVA DLSHIE K  V  + G E+L  CL   D+VVIPAG+PR PGM+R+DLF +NA I+A LT + A+HCP A+IC+I NP                                           +D  +++VPVIGGH+G TIIP+ISQ  P V FP ++   +  +I+ AG+E+V+AKAG GSATLSM++A  RF+ SL++A  G+ GV+E ++VKS ETEC YF++ LL G++G+E+NLGIG+++ FE  ++  AIP +K  I+ G+ + K+
Sbjct:   10 SAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANP------------------------------------------GLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKT 294
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Human
Match: MDH2 (malate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:6971])

HSP 1 Score: 260.766 bits (665), Expect = 9.078e-86
Identity = 113/229 (49.34%), Postives = 171/229 (74.67%), Query Frame = 2 
Query:  371 MSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKS 1057
            M+R+DLF +NA I+A LT + A+HCP A+IC+I NP+NS +P+ AE+     V++  K+FG+TTL  +RA TF+A+ K +D  +++VPVIGGH+G TIIP+ISQ  P V FP ++   +  +I+ AG+E+V+AKAG GSATLSM++A  RF+ SL++A  G+ GV+E ++VKS ETEC YF++ LL G++G+E+NLGIG+++ FE  ++  AIP +K  I+ G+ + K+
Sbjct:    1 MTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKT 229
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Human
Match: LDHA (lactate dehydrogenase A [Source:HGNC Symbol;Acc:HGNC:6535])

HSP 1 Score: 51.2174 bits (121), Expect = 7.172e-7
Identity = 54/208 (25.96%), Postives = 94/208 (45.19%), Query Frame = 2 
Query:   74 KSVLFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDI--KNVKGVAVDLSH---IERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGI-TTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVIS 679
            K  L  N  +  Q    K++V+G  G +G    +      L +ELAL D+    +KG  +DL H     R  K+ +  GK+        S +V+I AG  +  G SR +L + N  I   +  ++ K+ PN  + +++NP++ L  +  +I    + F   ++ G    L + R    + +   +     H  V+G H G + +PV S
Sbjct:    5 KDQLIYNLLKEEQTPQNKITVVGV-GAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVS--GKDY--NVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKI----SGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEH-GDSSVPVWS 202
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Human
Match: LDHA (lactate dehydrogenase A [Source:HGNC Symbol;Acc:HGNC:6535])

HSP 1 Score: 51.2174 bits (121), Expect = 7.172e-7
Identity = 54/208 (25.96%), Postives = 94/208 (45.19%), Query Frame = 2 
Query:   74 KSVLFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDI--KNVKGVAVDLSH---IERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGI-TTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVIS 679
            K  L  N  +  Q    K++V+G  G +G    +      L +ELAL D+    +KG  +DL H     R  K+ +  GK+        S +V+I AG  +  G SR +L + N  I   +  ++ K+ PN  + +++NP++ L  +  +I    + F   ++ G    L + R    + +   +     H  V+G H G + +PV S
Sbjct:    5 KDQLIYNLLKEEQTPQNKITVVGV-GAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVS--GKDY--NVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKI----SGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEH-GDSSVPVWS 202
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Celegans
Match: mdh-2 (Probable malate dehydrogenase, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:O02640])

HSP 1 Score: 309.686 bits (792), Expect = 6.665e-104
Identity = 153/328 (46.65%), Postives = 224/328 (68.29%), Query Frame = 2 
Query:   74 KSVLFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETE-CEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAK 1054
            ++V  R+S ++      KV++LGAAGGIGQPL L  K+ PL+  LALYD+ N  GVA DLSHI+   KVTA  G +EL A ++ +D++VIPAG+PR PGM+R+DLF +NA I+ +L   IAK  P ALI +ITNP+NS VP+ +E+L    V+D K++FG+TTL  +R+  F+++ K  D +K  VPV+GGH+G TIIP++SQ  P  +F  EE + +  +I++AG+E+V AKAG GSATLSM+ A  RF N+L+    G   V + AYV SD  +  EYF++ +  G  GVE+ LG+G+++ +E  L+ A++P + ++I  G  + K
Sbjct:   18 RAVSVRHSSQA-----PKVALLGAAGGIGQPLGLLLKQDPLVAHLALYDVVNTPGVAADLSHIDSNAKVTAHTGPKELYAAVENADVIVIPAGVPRKPGMTRDDLFNTNAGIVRDLAAVIAKASPKALIAIITNPVNSTVPIASEVLKKAGVYDPKRVFGVTTLDVVRSQAFVSELKGHDASKTVVPVVGGHAGITIIPLLSQVKPSTKFSEEEISKLTPRIQDAGTEVVNAKAGAGSATLSMALAGARFANALVRGIKGEKNV-QCAYVASDAVKGVEYFSTPVELGPNGVEKILGVGKVSAYEQKLIDASVPELNKNIAKGVAFVK 339
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Fly
Match: Mdh2 (gene:FBgn0262559 transcript:FBtr0083563)

HSP 1 Score: 331.257 bits (848), Expect = 3.277e-112
Identity = 159/316 (50.32%), Postives = 222/316 (70.25%), Query Frame = 2 
Query:  110 QIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKS 1057
            Q   YKV+V GAAGGIGQPL L  K+ PL+ +LALYDI +  GVA DLSHI+ K K   F G ++LG  L  SD+VVIPAG+PR PGM+R+DLF  NA II +++ SIAK+CP AL+ +ITNP+N+ VP+ AEIL    V+D K+LFG++TL  +RA  FI  A  +D   + +PVIGGHSG TI+PV+SQS P  +   +    +  +I+ AG+E+V+AKAG GSATLSM++A  RF  SL++   G   VIE +YV+S  TE  +F++ L+ G+ GV+ NLG+ ++ ++E  LL+AAIP +K++I+ G  +A +
Sbjct:   21 QQNNYKVTVCGAAGGIGQPLSLLLKQNPLVTDLALYDIVHTPGVAADLSHIDTKSKTAGFIGADQLGDSLKGSDVVVIPAGVPRKPGMTRDDLFNVNAGIIKDISNSIAKNCPKALVAIITNPVNTCVPIAAEILKKAGVYDPKRLFGVSTLDVVRARAFIGHALGVDPQTVQIPVIGGHSGVTILPVLSQSQPLFKGNQDTIEKLTVRIQEAGTEVVKAKAGAGSATLSMAYAGARFAGSLLKGLNGEKNVIECSYVQSTVTEATFFSTPLVLGKNGVQENLGLPKLNDYEKKLLEAAIPELKKNIQKGIDFANA 336
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Fly
Match: CG10749 (gene:FBgn0036328 transcript:FBtr0075871)

HSP 1 Score: 303.138 bits (775), Expect = 5.259e-101
Identity = 149/318 (46.86%), Postives = 210/318 (66.04%), Query Frame = 2 
Query:  116 RTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTG--VIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKSYL 1063
            R  KV+V+G+ GGIGQPL L  K  P I  L+LYDIKN  GV VDLSHI  +  V  FEGK  L   +DK+DIVVIPAGLPR PGM R DL   NA++  E+  + ++ CP A++  ITNP+N +VP++A IL     +D  +LFG+TTL  +RA TF+A   N+D  K+++PVIGGH+G TI+P++SQ  P  +   +ER  ++ +I+NAG+E+V AK G GSATLSM++AA +F++SLI+   G     ++E AYV+SD TE ++FA+ L+ G QGV+ N G+  + + E   L   +P +K  I  G K  +  +
Sbjct:   26 RGLKVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDIKNTTGVGVDLSHINTRASVCPFEGKNGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFITNPINVIVPIVATILKAKGTYDPNRLFGVTTLDVVRAQTFVADILNVDPQKVNIPVIGGHTGRTILPILSQCDPPFKGTDKEREALIQRIQNAGTEVVNAKDGLGSATLSMAFAATQFVSSLIKGIKGSKDECIVECAYVESDVTEAQFFATPLILGPQGVKENTGLPDLDDEERKALNGMLPILKESIAKGIKLGEGMI 343
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Fly
Match: CG10748 (gene:FBgn0036327 transcript:FBtr0075900)

HSP 1 Score: 272.322 bits (695), Expect = 5.671e-89
Identity = 140/318 (44.03%), Postives = 214/318 (67.30%), Query Frame = 2 
Query:  113 IRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKSYLS 1066
            +RT KV+V+GA GGIGQPL L  ++ P I+ELAL+D+  +KG+A DLSHI + GKV  F G++EL + +  +D+VV+ AG+PR PGM R+ L  +N  +  ++  +I+   P A +  ITNP+N +VP  AE+L     FDS++LFGITTL  +R+  FI  + NI    +++PVIGGH+G TI+P+ISQ  P  +  L+E   +  +I+ AG+E+V AKAG+GSATLSM++A   F+NSL+    G+ G+IE A+V S  T+  +FAS L  G+ G++R + + QM+++E   L+  +P ++++ + G  +AK  LS
Sbjct:   20 VRTLKVAVVGAGGGIGQPLSLLLRRCPGIDELALHDLSEMKGIATDLSHISQTGKVIGFTGEKELESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNASPRAHLAFITNPVNMIVPAAAEVLMAHGTFDSRRLFGITTLDVVRSKKFIGDSMNISPDDVNIPVIGGHAGITILPLISQCQPIYRCDLQEIQNLTHRIQEAGTEVVNAKAGKGSATLSMAYAGATFVNSLLRGIAGQDGLIECAFVASKLTDAPFFASPLELGKDGIKRYIPLPQMSDYEKEALEKLLPILRQNADEGVNFAKMILS 337
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Zebrafish
Match: mdh2 (malate dehydrogenase 2, NAD (mitochondrial) [Source:ZFIN;Acc:ZDB-GENE-040426-2143])

HSP 1 Score: 342.813 bits (878), Expect = 1.087e-116
Identity = 152/308 (49.35%), Postives = 230/308 (74.68%), Query Frame = 2 
Query:  125 KVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKY 1048
            KV+VLGA+GGIGQPL L  K +PL+ EL+L+DI +  GVA DLSHIE +  V  + G ++LG  L   ++VVIPAG+PR PGM+R+DLF +NA I+A L    A+HCP A+IC+I+NP+NS +P+ +E++    V++  K+FG+TTL  +RA TF+A+ K +D  +++VPV+GGH+G TIIP+ISQ  P V+FP ++ + +  +I+ AG+E+V+AKAG GSATLSM++A  RF  SL++A  G+ GV+E ++V+S+ETEC+YF++ LL G+ G+E+NLG+G+++ FE  L+  A+  +K  I+ G+ +
Sbjct:   25 KVAVLGASGGIGQPLSLLLKNSPLVSELSLFDIAHTPGVAADLSHIETRAHVKGYIGADQLGDALKGCEVVVIPAGVPRKPGMTRDDLFNTNATIVATLVDGCARHCPQAMICIISNPVNSTIPITSEVMKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVVGGHAGITIIPLISQCTPKVEFPADQLSALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFTFSLLDAMNGKEGVVECSFVRSEETECKYFSTPLLLGKNGIEKNLGLGKLSAFEEKLVADAMTELKGSIKKGEDF 332
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Zebrafish
Match: ldha (lactate dehydrogenase A4 [Source:NCBI gene;Acc:30496])

HSP 1 Score: 49.6766 bits (117), Expect = 2.437e-6
Identity = 44/165 (26.67%), Postives = 77/165 (46.67%), Query Frame = 2 
Query:  194 LIEELALYDI--KNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGI-TTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVIS 679
            L +ELAL D+    +KG A+DL H     K       ++     + S +VV+ AG  +  G SR +L + N  I   +  +I K+ PN ++ +++NP    V ++  +    +     ++ G  T L + R    + +   I  +  H  V+G H G + +PV S
Sbjct:   45 LTDELALVDVMEDKLKGEAMDLQHGSLFLKTHKIVADKDYSVTAN-SKVVVVTAGARQQEGESRLNLVQRNVNIFKFIIPNIIKYSPNCILLVVSNP----VDILTYVAWKLSGLPRNRVIGSGTNLDSARFRYLMGEKLGIHPSSCHGWVVGEH-GDSSVPVWS 203
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Zebrafish
Match: ldha (lactate dehydrogenase A4 [Source:NCBI gene;Acc:30496])

HSP 1 Score: 49.6766 bits (117), Expect = 2.437e-6
Identity = 44/165 (26.67%), Postives = 77/165 (46.67%), Query Frame = 2 
Query:  194 LIEELALYDI--KNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGI-TTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVIS 679
            L +ELAL D+    +KG A+DL H     K       ++     + S +VV+ AG  +  G SR +L + N  I   +  +I K+ PN ++ +++NP    V ++  +    +     ++ G  T L + R    + +   I  +  H  V+G H G + +PV S
Sbjct:   45 LTDELALVDVMEDKLKGEAMDLQHGSLFLKTHKIVADKDYSVTAN-SKVVVVTAGARQQEGESRLNLVQRNVNIFKFIIPNIIKYSPNCILLVVSNP----VDILTYVAWKLSGLPRNRVIGSGTNLDSARFRYLMGEKLGIHPSSCHGWVVGEH-GDSSVPVWS 203
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Zebrafish
Match: ldhbb (lactate dehydrogenase Bb [Source:NCBI gene;Acc:436747])

HSP 1 Score: 48.9062 bits (115), Expect = 4.807e-6
Identity = 47/169 (27.81%), Postives = 82/169 (48.52%), Query Frame = 2 
Query:  194 LIEELALYDI--KNVKGVAVDLSH---IERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEI--LNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVIS 679
            L +ELAL D+    +KG  +DL H     +  K+ +  GK+   +    S IVV+ AG+ +  G SR +L + N  I   +   I K+ PN ++ +++NP++ L  +  ++  L    V  S      T L + R    +A+   I  +  +  ++G H G + +PV S
Sbjct:   45 LADELALVDVVEDKLKGEMMDLQHGSLFLKTPKIVS--GKDY--SVTANSRIVVVTAGVRQQEGESRLNLVQRNVNIFKHIIPQIVKYSPNCILIVVSNPVDVLTYVTWKLSGLPKHRVIGSG-----TNLDSARFRYLMAERLGIHPSSFNGWILGEH-GDSSVPVWS 203
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Zebrafish
Match: ldhbb (lactate dehydrogenase Bb [Source:NCBI gene;Acc:436747])

HSP 1 Score: 48.521 bits (114), Expect = 6.148e-6
Identity = 47/169 (27.81%), Postives = 82/169 (48.52%), Query Frame = 2 
Query:  194 LIEELALYDI--KNVKGVAVDLSH---IERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEI--LNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVIS 679
            L +ELAL D+    +KG  +DL H     +  K+ +  GK+   +    S IVV+ AG+ +  G SR +L + N  I   +   I K+ PN ++ +++NP++ L  +  ++  L    V  S      T L + R    +A+   I  +  +  ++G H G + +PV S
Sbjct:   45 LADELALVDVVEDKLKGEMMDLQHGSLFLKTPKIVS--GKDY--SVTANSRIVVVTAGVRQQEGESRLNLVQRNVNIFKHIIPQIVKYSPNCILIVVSNPVDVLTYVTWKLSGLPKHRVIGSG-----TNLDSARFRYLMAERLGIHPSSFNGWILGEH-GDSSVPVWS 203
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Xenopus
Match: sssca1 (Sjogren syndrome/scleroderma autoantigen 1 [Source:Xenbase;Acc:XB-GENE-5770639])

HSP 1 Score: 355.91 bits (912), Expect = 1.003e-121
Identity = 165/328 (50.30%), Postives = 240/328 (73.17%), Query Frame = 2 
Query:   83 LFRNSC---RSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKS 1057
            L R SC   R+      +V+VLGA+GGIGQPL L  K +PLI  L LYDI +  GVA DLSHIE + KVT + G E+L   L  +D+VVIPAG+PR PGM+R+DLF +NA+I+A LT + AKHCP A+IC+I+NP+NS +P+ +E+     V++   +FG+TTL  +RA TF+A+ K +D  +++VPV+GGH+G TIIP+ISQS P V+FP ++   ++ +I++AG+E+V+AKAG GSATLSM++A  RF+ SL++A  G+ GVIE ++V+S+ETE  YF++ LL G+ G+E+NLG+G++T FE  L+  A+  +K  I+ G+ + KS
Sbjct:    6 LVRKSCFLNRTPFCANARVAVLGASGGIGQPLSLLLKNSPLISNLTLYDIAHTPGVAADLSHIETRAKVTGYLGAEQLPESLKGADVVVIPAGVPRKPGMTRDDLFTTNASIVATLTEACAKHCPEAMICIISNPVNSTIPITSEVFKKHGVYNPNHIFGVTTLDIVRANTFVAELKGLDPARVNVPVVGGHAGKTIIPLISQSTPKVEFPQDQLEALIPRIQDAGTEVVKAKAGAGSATLSMAYAGARFVFSLLDAMNGKEGVIECSFVRSEETESPYFSTPLLLGKNGIEKNLGLGKLTAFEEKLVSEAMGELKASIKKGEDFIKS 333
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Xenopus
Match: sssca1 (Sjogren syndrome/scleroderma autoantigen 1 [Source:Xenbase;Acc:XB-GENE-5770639])

HSP 1 Score: 353.599 bits (906), Expect = 4.096e-121
Identity = 160/311 (51.45%), Postives = 234/311 (75.24%), Query Frame = 2 
Query:  125 KVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKS 1057
            +V+VLGA+GGIGQPL L  K +PLI  L LYDI +  GVA DLSHIE + KVT + G E+L   L  +D+VVIPAG+PR PGM+R+DLF +NA+I+A LT + AKHCP A+IC+I+NP+NS +P+ +E+     V++   +FG+TTL  +RA TF+A+ K +D  +++VPV+GGH+G TIIP+ISQS P V+FP ++   ++ +I++AG+E+V+AKAG GSATLSM++A  RF+ SL++A  G+ GVIE ++V+S+ETE  YF++ LL G+ G+E+NLG+G++T FE  L+  A+  +K  I+ G+ + KS
Sbjct:    6 RVAVLGASGGIGQPLSLLLKNSPLISNLTLYDIAHTPGVAADLSHIETRAKVTGYLGAEQLPESLKGADVVVIPAGVPRKPGMTRDDLFTTNASIVATLTEACAKHCPEAMICIISNPVNSTIPITSEVFKKHGVYNPNHIFGVTTLDIVRANTFVAELKGLDPARVNVPVVGGHAGKTIIPLISQSTPKVEFPQDQLEALIPRIQDAGTEVVKAKAGAGSATLSMAYAGARFVFSLLDAMNGKEGVIECSFVRSEETESPYFSTPLLLGKNGIEKNLGLGKLTAFEEKLVSEAMGELKASIKKGEDFIKS 316
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Xenopus
Match: sssca1 (Sjogren syndrome/scleroderma autoantigen 1 [Source:Xenbase;Acc:XB-GENE-5770639])

HSP 1 Score: 353.984 bits (907), Expect = 4.277e-121
Identity = 160/311 (51.45%), Postives = 234/311 (75.24%), Query Frame = 2 
Query:  125 KVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKS 1057
            +V+VLGA+GGIGQPL L  K +PLI  L LYDI +  GVA DLSHIE + KVT + G E+L   L  +D+VVIPAG+PR PGM+R+DLF +NA+I+A LT + AKHCP A+IC+I+NP+NS +P+ +E+     V++   +FG+TTL  +RA TF+A+ K +D  +++VPV+GGH+G TIIP+ISQS P V+FP ++   ++ +I++AG+E+V+AKAG GSATLSM++A  RF+ SL++A  G+ GVIE ++V+S+ETE  YF++ LL G+ G+E+NLG+G++T FE  L+  A+  +K  I+ G+ + KS
Sbjct:   14 RVAVLGASGGIGQPLSLLLKNSPLISNLTLYDIAHTPGVAADLSHIETRAKVTGYLGAEQLPESLKGADVVVIPAGVPRKPGMTRDDLFTTNASIVATLTEACAKHCPEAMICIISNPVNSTIPITSEVFKKHGVYNPNHIFGVTTLDIVRANTFVAELKGLDPARVNVPVVGGHAGKTIIPLISQSTPKVEFPQDQLEALIPRIQDAGTEVVKAKAGAGSATLSMAYAGARFVFSLLDAMNGKEGVIECSFVRSEETESPYFSTPLLLGKNGIEKNLGLGKLTAFEEKLVSEAMGELKASIKKGEDFIKS 324
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Xenopus
Match: sssca1 (Sjogren syndrome/scleroderma autoantigen 1 [Source:Xenbase;Acc:XB-GENE-5770639])

HSP 1 Score: 353.599 bits (906), Expect = 4.482e-121
Identity = 160/311 (51.45%), Postives = 234/311 (75.24%), Query Frame = 2 
Query:  125 KVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKS 1057
            +V+VLGA+GGIGQPL L  K +PLI  L LYDI +  GVA DLSHIE + KVT + G E+L   L  +D+VVIPAG+PR PGM+R+DLF +NA+I+A LT + AKHCP A+IC+I+NP+NS +P+ +E+     V++   +FG+TTL  +RA TF+A+ K +D  +++VPV+GGH+G TIIP+ISQS P V+FP ++   ++ +I++AG+E+V+AKAG GSATLSM++A  RF+ SL++A  G+ GVIE ++V+S+ETE  YF++ LL G+ G+E+NLG+G++T FE  L+  A+  +K  I+ G+ + KS
Sbjct:    8 RVAVLGASGGIGQPLSLLLKNSPLISNLTLYDIAHTPGVAADLSHIETRAKVTGYLGAEQLPESLKGADVVVIPAGVPRKPGMTRDDLFTTNASIVATLTEACAKHCPEAMICIISNPVNSTIPITSEVFKKHGVYNPNHIFGVTTLDIVRANTFVAELKGLDPARVNVPVVGGHAGKTIIPLISQSTPKVEFPQDQLEALIPRIQDAGTEVVKAKAGAGSATLSMAYAGARFVFSLLDAMNGKEGVIECSFVRSEETESPYFSTPLLLGKNGIEKNLGLGKLTAFEEKLVSEAMGELKASIKKGEDFIKS 318
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Xenopus
Match: sssca1 (Sjogren syndrome/scleroderma autoantigen 1 [Source:Xenbase;Acc:XB-GENE-5770639])

HSP 1 Score: 353.984 bits (907), Expect = 5.517e-121
Identity = 164/328 (50.00%), Postives = 240/328 (73.17%), Query Frame = 2 
Query:   74 KSVLFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKS 1057
            KS L+ N+         +V+VLGA+GGIGQPL L  K +PLI  L LYDI +  GVA DLSHIE + KVT + G E+L   L  +D+VVIPAG+PR PGM+R+DLF +NA+I+A LT + AKHCP A+IC+I+NP+NS +P+ +E+     V++   +FG+TTL  +RA TF+A+ K +D  +++VPV+GGH+G TIIP+ISQS P V+FP ++   ++ +I++AG+E+V+AKAG GSATLSM++A  RF+ SL++A  G+ GVIE ++V+S+ETE  YF++ LL G+ G+E+NLG+G++T FE  L+  A+  +K  I+ G+ + KS
Sbjct:    9 KSCLYANA---------RVAVLGASGGIGQPLSLLLKNSPLISNLTLYDIAHTPGVAADLSHIETRAKVTGYLGAEQLPESLKGADVVVIPAGVPRKPGMTRDDLFTTNASIVATLTEACAKHCPEAMICIISNPVNSTIPITSEVFKKHGVYNPNHIFGVTTLDIVRANTFVAELKGLDPARVNVPVVGGHAGKTIIPLISQSTPKVEFPQDQLEALIPRIQDAGTEVVKAKAGAGSATLSMAYAGARFVFSLLDAMNGKEGVIECSFVRSEETESPYFSTPLLLGKNGIEKNLGLGKLTAFEEKLVSEAMGELKASIKKGEDFIKS 327
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Mouse
Match: Mdh2 (malate dehydrogenase 2, NAD (mitochondrial) [Source:MGI Symbol;Acc:MGI:97050])

HSP 1 Score: 357.451 bits (916), Expect = 1.994e-122
Identity = 162/324 (50.00%), Postives = 232/324 (71.60%), Query Frame = 2 
Query:   86 FRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKS 1057
             R S  +      KV+VLGA+GGIGQPL L  K +PL+  L LYDI +  GVA DLSHIE +  V  + G E+L  CL   D+VVIPAG+PR PGM+R+DLF +NA I+A LT + A+HCP A++C+I NP+NS +P+ AE+     V++  K+FG+TTL  +RA TF+A+ K +D  +++VPVIGGH+G TIIP+ISQ  P V FP ++   +  +I+ AG+E+V+AKAG GSATLSM++A  RF+ SL++A  G+ GV+E ++V+S ETEC YF++ LL G++G+E+NLGIG++T FE  ++  AIP +K  I+ G+ + K+
Sbjct:   13 LRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMVCIIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLATLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVQSKETECTYFSTPLLLGKKGLEKNLGIGKITPFEEKMIAEAIPELKASIKKGEDFVKN 336
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Mouse
Match: Mdh2 (malate dehydrogenase 2, NAD (mitochondrial) [Source:MGI Symbol;Acc:MGI:97050])

HSP 1 Score: 200.675 bits (509), Expect = 6.682e-63
Identity = 87/167 (52.10%), Postives = 122/167 (73.05%), Query Frame = 2 
Query:  182 KKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQ 682
            + +PL+  L LYDI +  GVA DLSHIE +  V  + G E+L  CL   D+VVIPAG+PR PGM+R+DLF +NA I+A LT + A+HCP A++C+I NP+NS +P+ AE+     V++  K+FG+TTL  +RA TF+A+ K +D  +++VPVIGGH+G TIIP+ISQ
Sbjct:   22 QNSPLVSRLTLYDIAHTPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMVCIIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQ 188
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Mouse
Match: Mdh2 (malate dehydrogenase 2, NAD (mitochondrial) [Source:MGI Symbol;Acc:MGI:97050])

HSP 1 Score: 144.05 bits (362), Expect = 1.087e-41
Identity = 69/156 (44.23%), Postives = 94/156 (60.26%), Query Frame = 2 
Query:  125 KVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFI 592
            KV+VLGA+GGIGQPL L  K +PL+  L LYDI +  GVA DLSHIE +  V                             GM+R+DLF +NA I+A LT + A+HCP A++C+I NP+NS +P+ AE+     V++  K+FG+TTL  +RA TF+
Sbjct:   26 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRANVK----------------------------GMTRDDLFNTNATIVATLTAACAQHCPEAMVCIIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFV 153
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Mouse
Match: Ldhal6b (lactate dehydrogenase A-like 6B [Source:MGI Symbol;Acc:MGI:2146830])

HSP 1 Score: 51.6026 bits (122), Expect = 9.068e-7
Identity = 49/188 (26.06%), Postives = 84/188 (44.68%), Query Frame = 2 
Query:  125 KVSVLGAAGGIGQPLCLFCKKTPLIEELALYDI--KNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGI-TTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVIS 679
            KVS++G  G +G    +      L +ELAL D   + +KG  +DL H     K+      ++     + S++V+I AG  +    +R +L + N  I   +   I KH P   I +++NP++    ++  +    + F   ++ G    L T R    + Q   I     H  V+G H G + +PV S
Sbjct:   72 KVSIVGT-GSVGMACAIGIIAKGLTDELALVDNNEEKMKGETMDLQHGSVFMKMPNIVCSKDFRVTAN-SEVVIITAGARQEKNETRLNLVQRNVTIFKAMVAEIIKHSPRCKIIVVSNPVD----ILTFVTWKLSGFPKNRIIGSGCNLDTARFRYMLGQRLGIHSESCHGWVLGEH-GDSSVPVWS 252
[Close]
BLAST of Malate dehydrogenase vs. UniProt/SwissProt
Match: sp|Q5NVR2|MDHM_PONAB (Malate dehydrogenase, mitochondrial OS=Pongo abelii OX=9601 GN=MDH2 PE=2 SV=1)

HSP 1 Score: 362.073 bits (928), Expect = 2.261e-123
Identity = 165/327 (50.46%), Postives = 234/327 (71.56%), Query Frame = 2 
Query:   77 SVLFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKS 1057
            S + R S  +      KV+VLGA+GGIGQPL L  K +PL+  L LYDI +  GVA DLSHIE K  V  + G E+L  CL   D+VVIPAG+PR PGM+R+DLF +NA I+A LT + A+HCP A+IC+I NP+NS +P+ AE+     V++  K+FG+TTL  +RA TF+A+ K +D  +++VPVIGGH+G TIIP+ISQ  P V FP ++   +  +I+ AG+E+V+AKAG GSATLSM++A  RF+ SL++A  G+ GV+E ++VKS ETEC YF++ LL G++G+E+NLGIG+++ FE  ++  AIP +K  I+ G+ + K+
Sbjct:   10 SAVLRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKATVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTSACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKT 336
[Close]
BLAST of Malate dehydrogenase vs. UniProt/SwissProt
Match: sp|P40926|MDHM_HUMAN (Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3)

HSP 1 Score: 361.688 bits (927), Expect = 3.312e-123
Identity = 165/327 (50.46%), Postives = 233/327 (71.25%), Query Frame = 2 
Query:   77 SVLFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKS 1057
            S   R S  +      KV+VLGA+GGIGQPL L  K +PL+  L LYDI +  GVA DLSHIE K  V  + G E+L  CL   D+VVIPAG+PR PGM+R+DLF +NA I+A LT + A+HCP A+IC+I NP+NS +P+ AE+     V++  K+FG+TTL  +RA TF+A+ K +D  +++VPVIGGH+G TIIP+ISQ  P V FP ++   +  +I+ AG+E+V+AKAG GSATLSM++A  RF+ SL++A  G+ GV+E ++VKS ETEC YF++ LL G++G+E+NLGIG+++ FE  ++  AIP +K  I+ G+ + K+
Sbjct:   10 SAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKT 336
[Close]
BLAST of Malate dehydrogenase vs. UniProt/SwissProt
Match: sp|P04636|MDHM_RAT (Malate dehydrogenase, mitochondrial OS=Rattus norvegicus OX=10116 GN=Mdh2 PE=1 SV=2)

HSP 1 Score: 359.377 bits (921), Expect = 2.410e-122
Identity = 167/336 (49.70%), Postives = 238/336 (70.83%), Query Frame = 2 
Query:   56 MLQSFNKSV--LFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKS 1057
            ML +  + V    R S  +      KV+VLGA+GGIGQPL L  K +PL+  L LYDI +  GVA DLSHIE +  V  + G E+L  CL   D+VVIPAG+PR PGM+R+DLF +NA I+A LT + A+HCP A+IC+I+NP+NS +P+ AE+     V++  K+FG+TTL  +RA TF+A+ K +D  +++VPVIGGH+G TIIP+ISQ  P V FP ++   +  +I+ AG+E+V+AKAG GSATLSM++A  RF+ SL++A  G+ GVIE ++V+S ETEC YF++ LL G++G+E+NLGIG++T FE  ++  AIP +K  I+ G+ + K+
Sbjct:    1 MLSALARPVGAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICIISNPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLATLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVIECSFVQSKETECTYFSTPLLLGKKGLEKNLGIGKITPFEEKMIAEAIPELKASIKKGEDFVKN 336
[Close]
BLAST of Malate dehydrogenase vs. UniProt/SwissProt
Match: sp|Q32LG3|MDHM_BOVIN (Malate dehydrogenase, mitochondrial OS=Bos taurus OX=9913 GN=MDH2 PE=1 SV=1)

HSP 1 Score: 358.607 bits (919), Expect = 5.642e-122
Identity = 161/324 (49.69%), Postives = 235/324 (72.53%), Query Frame = 2 
Query:   86 FRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKS 1057
             R S  +      KV+VLGA+GGIGQPL L  K +PL+  L LYDI +  GVA DLSHIE +  V  + G E+L  CL   D+VVIPAG+PR PGM+R+DLF +NA I+A LT + A+HCP A+IC+I+NP+NS +P+ AE+     V++  K+FG+TTL  +RA  F+A+ K++D  +++VPVIGGH+G TIIP+ISQ  P V+FP ++   +  +I+ AG+E+V+AKAG GSATLSM++A  RF+ SL++A  G+ GV+E ++VKS ET+C YF++ LL G++G+E+NLGIG+++ FE  ++  AIP +K  I+ G+++ K+
Sbjct:   13 LRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRATVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICIISNPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANAFVAELKDLDPARVNVPVIGGHAGKTIIPLISQCTPKVEFPQDQLTTLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETDCPYFSTPLLLGKKGIEKNLGIGKVSPFEEKMIAEAIPELKASIKKGEEFVKN 336
[Close]
BLAST of Malate dehydrogenase vs. UniProt/SwissProt
Match: sp|P00346|MDHM_PIG (Malate dehydrogenase, mitochondrial OS=Sus scrofa OX=9823 GN=MDH2 PE=1 SV=2)

HSP 1 Score: 357.836 bits (917), Expect = 1.171e-121
Identity = 161/324 (49.69%), Postives = 234/324 (72.22%), Query Frame = 2 
Query:   86 FRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKS 1057
             R S  +      KV+VLGA+GGIGQPL L  K +PL+  L LYDI +  GVA DLSHIE +  V  + G E+L  CL   D+VVIPAG+PR PGM+R+DLF +NA I+A LT + A+HCP+A+IC+I+NP+NS +P+ AE+     V++  K+FG+TTL  +RA  F+A+ K +D  ++ VPVIGGH+G TIIP+ISQ  P V FP ++ + +  +I+ AG+E+V+AKAG GSATLSM++A  RF+ SL++A  G+ GV+E ++VKS ET+C YF++ LL G++G+E+NLGIG+++ FE  ++  AIP +K  I+ G+++ K+
Sbjct:   13 LRRSFSTSXQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRATVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPDAMICIISNPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANAFVAELKGLDPARVSVPVIGGHAGKTIIPLISQCTPKVDFPQDQLSTLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETDCPYFSTPLLLGKKGIEKNLGIGKISPFEEKMIAEAIPELKASIKKGEEFVKN 336
[Close]
BLAST of Malate dehydrogenase vs. TrEMBL
Match: G4VBJ0 (Malate dehydrogenase OS=Schistosoma mansoni OX=6183 GN=Smp_047370 PE=3 SV=1)

HSP 1 Score: 397.127 bits (1019), Expect = 1.188e-134
Identity = 190/331 (57.40%), Postives = 252/331 (76.13%), Query Frame = 2 
Query:   68 FNKSVLFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKSY 1060
            F   + FR+   S +  + KV+VLGA+GGIGQPL L  K++PLI +LALYDI +VKGVA DLSHIE +  VTA  G  EL  CL  +++V+IPAG+PR PGM+R+DLF +NA+I+AEL  S AK+CP A+IC+ITNP+NS VP+ AEIL   NV+D K+LFG+TTL  +R+ TFIAQAK++ + K+  PVIGGHSG TI+PVISQ +PHV FP +ER  I  +I+ AG+E+VEAKAG GSATLSM++A  RF  SL+EA  GR GV+E A+V+SD TECE+F++ L  G +GVE+N+GIG++ E+EI LLK  IP +K +I+ GK++A  Y
Sbjct:    9 FRFGISFRSFLTSSK-HSPKVAVLGASGGIGQPLSLLLKQSPLISQLALYDIAHVKGVAADLSHIETQAHVTAHLGPGELAECLTGANVVIIPAGMPRKPGMTRDDLFNTNASIVAELIDSCAKNCPKAMICIITNPVNSTVPIAAEILKRHNVYDPKRLFGVTTLDVVRSNTFIAQAKDLAVRKVSCPVIGGHSGITILPVISQCSPHVSFPQDEREKITKRIQEAGTEVVEAKAGAGSATLSMAYAGVRFAVSLLEAMSGRAGVVECAFVESDVTECEFFSTPLALGAEGVEKNMGIGKLNEYEIELLKKLIPELKANIKKGKEFAAKY 338
[Close]
BLAST of Malate dehydrogenase vs. TrEMBL
Match: A0A430QMD7 (Malate dehydrogenase OS=Schistosoma bovis OX=6184 GN=DC041_0012974 PE=3 SV=1)

HSP 1 Score: 397.127 bits (1019), Expect = 1.446e-134
Identity = 189/331 (57.10%), Postives = 253/331 (76.44%), Query Frame = 2 
Query:   68 FNKSVLFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKSY 1060
            F   + FR+   S +  + KV+VLGA+GGIGQPL L  K++PLI +L+LYDI +VKGVA DLSHIE + +VTA  G  EL  CL  +++V+IPAG+PR PGM+R+DLF +NA+I+AEL  S AK+CP A+IC+ITNP+NS VP+ AEIL   NV+D K+LFG+TTL  +R+ TFIAQAK++ + K+  PVIGGHSG TI+PVISQ +PHV FP +ER  I  +I+ AG+E+VEAKAG GSATLSM++A  RF  SL+EA  GR GV+E A+V+SD TECE+F++ L  G +GVE+N+GIG++ E+EI LLK  IP +K +I+ GK++A  Y
Sbjct:    9 FRFGISFRSFLTSSK-HSPKVAVLGASGGIGQPLSLLLKQSPLISQLSLYDIAHVKGVAADLSHIETQAQVTAHLGPGELAECLSGANVVIIPAGMPRKPGMTRDDLFNTNASIVAELIDSCAKNCPKAMICIITNPVNSTVPIAAEILKRHNVYDPKRLFGVTTLDVVRSNTFIAQAKDLAVRKVSCPVIGGHSGITILPVISQCSPHVSFPQDEREKITKRIQEAGTEVVEAKAGAGSATLSMAYAGVRFAVSLLEAMSGRAGVVECAFVESDVTECEFFSTPLALGAEGVEKNMGIGKLNEYEIELLKKLIPELKANIKKGKEFAAKY 338
[Close]
BLAST of Malate dehydrogenase vs. TrEMBL
Match: A0A183LL11 (Malate dehydrogenase OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS4486 PE=3 SV=1)

HSP 1 Score: 397.127 bits (1019), Expect = 1.446e-134
Identity = 189/331 (57.10%), Postives = 253/331 (76.44%), Query Frame = 2 
Query:   68 FNKSVLFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKSY 1060
            F   + FR+   S +  + KV+VLGA+GGIGQPL L  K++PLI +L+LYDI +VKGVA DLSHIE + +VTA  G  EL  CL  +++V+IPAG+PR PGM+R+DLF +NA+I+AEL  S AK+CP A+IC+ITNP+NS VP+ AEIL   NV+D K+LFG+TTL  +R+ TFIAQAK++ + K+  PVIGGHSG TI+PVISQ +PHV FP +ER  I  +I+ AG+E+VEAKAG GSATLSM++A  RF  SL+EA  GR GV+E A+V+SD TECE+F++ L  G +GVE+N+GIG++ E+EI LLK  IP +K +I+ GK++A  Y
Sbjct:    9 FRFGISFRSFLTSSK-HSPKVAVLGASGGIGQPLSLLLKQSPLISQLSLYDIAHVKGVAADLSHIETQAQVTAHLGPGELAECLSGANVVIIPAGMPRKPGMTRDDLFNTNASIVAELIDSCAKNCPKAMICIITNPVNSTVPIAAEILKRHNVYDPKRLFGVTTLDVVRSNTFIAQAKDLAVRKVSCPVIGGHSGITILPVISQCSPHVSFPQDEREKITKRIQEAGTEVVEAKAGAGSATLSMAYAGVRFAVSLLEAMSGRAGVVECAFVESDVTECEFFSTPLALGAEGVEKNMGIGKLNEYEIELLKKLIPELKANIKKGKEFAAKY 338
[Close]
BLAST of Malate dehydrogenase vs. TrEMBL
Match: Q5D9T1 (Malate dehydrogenase OS=Schistosoma japonicum OX=6182 GN=Mor1 PE=2 SV=1)

HSP 1 Score: 392.889 bits (1008), Expect = 5.729e-133
Identity = 187/331 (56.50%), Postives = 252/331 (76.13%), Query Frame = 2 
Query:   68 FNKSVLFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKSY 1060
            F   + FR+   S +  + KV+VLGA+GGIGQPL L  K++PLI +LALYDI +VKGVA DLSHIE +  VT   G  ELG CL  +++V+IPAG+PR PGM+R+DLF +NA+I+AEL  + AK+CP A+IC+ITNP+NS VP+ AEIL   NV+D K+LFG+TTL  +R+ TFIAQAK++ + K+  PVIGGHSG TI+PVISQ +PHV FP +ER  I  +I+ AG+E+VEAKAG GSATLSM++A  RF  SL+EA  GR GV+E A+V+SD TECE+F++ L  G +GVE+N+GIG++ E+EI LLK  IP ++ +I+ GK++A  +
Sbjct:    9 FKFGITFRSFVTSPK-HSLKVAVLGASGGIGQPLSLLLKQSPLIYQLALYDIAHVKGVAADLSHIETQAHVTPHLGPGELGECLSGANLVMIPAGMPRKPGMTRDDLFNTNASIVAELINACAKNCPKAMICIITNPVNSTVPIAAEILKRHNVYDPKRLFGVTTLDVVRSNTFIAQAKDLAVRKVSCPVIGGHSGITILPVISQCSPHVSFPQDEREKITKRIQEAGTEVVEAKAGAGSATLSMAYAGARFAISLLEAMNGRAGVVECAFVQSDVTECEFFSTPLALGTEGVEKNMGIGKLNEYEIELLKKLIPELQANIKKGKEFAAKF 338
[Close]
BLAST of Malate dehydrogenase vs. TrEMBL
Match: C1LJM5 (Malate dehydrogenase OS=Schistosoma japonicum OX=6182 GN=Mor1 PE=2 SV=1)

HSP 1 Score: 390.578 bits (1002), Expect = 4.365e-132
Identity = 186/331 (56.19%), Postives = 252/331 (76.13%), Query Frame = 2 
Query:   68 FNKSVLFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKSY 1060
            F   + FR+   S +  + KV+VLGA+GGIGQPL L  K++PLI +LALYDI +VKGVA DLSHIE +  VT   G  ELG CL  +++V+IPAG+PR PGM+R+DLF +NA+I+AEL  + AK+CP A+IC+ITNP+NS VP+ AEIL   +V+D K+LFG+TTL  +R+ TFIAQAK++ + K+  PVIGGHSG TI+PVISQ +PHV FP +ER  I  +I+ AG+E+VEAKAG GSATLSM++A  RF  SL+EA  GR GV+E A+V+SD TECE+F++ L  G +GVE+N+GIG++ E+EI LLK  IP ++ +I+ GK++A  +
Sbjct:    9 FKFGITFRSFVTSPK-HSPKVAVLGASGGIGQPLSLLLKQSPLIYQLALYDIAHVKGVAADLSHIETQAHVTPHLGPGELGECLSGANLVMIPAGMPRKPGMTRDDLFNTNASIVAELINACAKNCPKAMICIITNPVNSTVPIAAEILKRHDVYDPKRLFGVTTLDVVRSNTFIAQAKDLAVRKVSCPVIGGHSGITILPVISQCSPHVSFPQDEREKITKRIQEAGTEVVEAKAGAGSATLSMAYAGARFAISLLEAMNGRAGVVECAFVQSDVTECEFFSTPLALGTEGVEKNMGIGKLNEYEIELLKKLIPELQANIKKGKEFAAKF 338
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Cavefish
Match: mdh2 (malate dehydrogenase 2 [Source:NCBI gene;Acc:103036822])

HSP 1 Score: 345.125 bits (884), Expect = 1.283e-117
Identity = 157/309 (50.81%), Postives = 232/309 (75.08%), Query Frame = 2 
Query:  125 KVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYA 1051
            KV+VLGAAGGIGQPL L  K +PL+ EL+LYDI +  GVA DLSHIE + KVT + G ++L A L   ++VVIPAG+PR PGM+R+DLF +NA I+A L+ + A+ CP A+IC+I NP+NS VP+ +E++    V++  ++FG+TTL  +RA  F+A+ K +D  +++VPVIGGH+G TIIP+ISQ  P V+FP ++ + +  +I++AG+E+V+AKAG GSATLSM++A  RF  SL++A  G+ GV+E A+V+S+ETEC+YF++ LL G+ G+E+NLG+G ++ FE  L+  A+  +K  I+ G+ +A
Sbjct:   25 KVAVLGAAGGIGQPLSLLLKNSPLVSELSLYDIAHTPGVAADLSHIETRAKVTGYIGPDQLEAALKGCEVVVIPAGVPRKPGMTRDDLFNTNATIVATLSDACARACPEAMICIIANPVNSTVPITSEMMKKHGVYNPNRVFGVTTLDIVRANAFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVEFPEDQLSALTVRIQDAGTEVVKAKAGAGSATLSMAYAGARFTFSLLDAMNGKEGVVECAFVRSEETECKYFSTPLLLGKNGIEKNLGVGTLSVFEKKLVAEALGELKGSIKKGEDFA 333
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Cavefish
Match: ldhba (lactate dehydrogenase B [Source:NCBI gene;Acc:103033414])

HSP 1 Score: 49.6766 bits (117), Expect = 2.342e-6
Identity = 46/166 (27.71%), Postives = 77/166 (46.39%), Query Frame = 2 
Query:  194 LIEELALYDI--KNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEI--LNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVIS 679
            L +ELAL D+    +KG  +DL H     K       ++     + S IVV+ AG+ +  G SR +L + N  I   +   I K+ PN  + +++NP++ L  +  ++  L    V  S      T L + R    +A+   I  T  +  ++G H G + +PV S
Sbjct:   44 LCDELALVDVVEDKLKGEMMDLQHGSLFLKTHKIVADKDYSVTAN-SRIVVVTAGVRQQEGESRLNLVQRNVNIFKHIIPQIVKYSPNCTLIVVSNPVDVLTYVTWKLSGLPKHRVIGSG-----TNLDSARFRYIMAEKLGIHATSFNGYILGEH-GDSSVPVWS 202
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Cavefish
Match: ldhbb (L-lactate dehydrogenase B-B chain [Source:NCBI gene;Acc:103028647])

HSP 1 Score: 49.6766 bits (117), Expect = 2.392e-6
Identity = 45/168 (26.79%), Postives = 81/168 (48.21%), Query Frame = 2 
Query:  194 LIEELALYDI--KNVKGVAVDLSH---IERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGI-TTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVIS 679
            L +ELAL D+    +KG  +DL H     +  K+ +  GK+   +    S IVV+ AG+ +  G SR +L + N  I   +   I ++ PN ++ +++NP    V ++  +    +     ++ G  T L + R    +A+   I  T  +  ++G H G + +PV S
Sbjct:   45 LADELALVDVMEDKLKGEMLDLQHGSLFLKTPKIVS--GKDY--SVTANSRIVVVTAGVRQQEGESRLNLVQRNVNIFKHIIPQIVRYSPNCILIVVSNP----VDILTYVTWKLSRLPKHRVIGSGTNLDSARFRYLMAERLGIHPTSFNGWILGEH-GDSSVPVWS 203
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Cavefish
Match: ldha (L-lactate dehydrogenase A chain [Source:NCBI gene;Acc:103047177])

HSP 1 Score: 48.9062 bits (115), Expect = 3.901e-6
Identity = 44/165 (26.67%), Postives = 77/165 (46.67%), Query Frame = 2 
Query:  194 LIEELALYDI--KNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGI-TTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVIS 679
            L +ELAL D+    +KG A+DL H     K       ++     + S +VV+ AG  +  G SR +L + N  I   +  +I K+ PN ++ +++NP    V ++  +    +     ++ G  T L + R    + +   +  +  H  VIG H G + +PV S
Sbjct:   45 LADELALVDVMEDKLKGEAMDLQHGSLFLKTHKIVADKDYSVTAN-SRVVVVTAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCIMLVVSNP----VDILTYVAWKLSGLPRNRVIGSGTNLDSARFRFLMGEKLGLHPSSCHGWVIGEH-GDSSVPVWS 203
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Sea Lamprey
Match: mdh2 (malate dehydrogenase 2, NAD (mitochondrial) [Source:ZFIN;Acc:ZDB-GENE-040426-2143])

HSP 1 Score: 297.745 bits (761), Expect = 1.023e-99
Identity = 152/331 (45.92%), Postives = 217/331 (65.56%), Query Frame = 2 
Query:   83 LFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNP---GMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDIT--KLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKSY 1060
            L R   R  Q    KV+VLGAAGGIGQPL L  K    +  LALYDI    GVAVDL HI     V+A +G  +L   LD S +VV+PAG+PR P   GM+R DLF  NA I+AEL  + A  CP AL+C+I+N +NS+VP+ +EI     V+D K++FG+TTL  +RA  F+A  K + +    L  PV+GGH+G TIIP++SQS P V    ++  M+  +++ AG+E+V+AK G+GSATLSM+ A  RF++SL+EA  G  G++E A+V+S+ETE  Y ++ LL G++GVER++G+ Q    E S+    +P +K  I  G+++A+++
Sbjct:   13 LLRRPRRGAQ-HGVKVAVLGAAGGIGQPLSLLLKMNARVSRLALYDIARAHGVAVDLGHINSHASVSAHQGANQLSEALDGSHLVVVPAGVPRKPAPEGMTREDLFTMNAHIVAELAEACAITCPQALLCIISNLVNSMVPIASEIFKKHGVYDPKRIFGVTTLDVVRASVFLADLKGLSMWCGWLFCPVVGGHAGKTIIPLLSQSLPKVDLGQDQIEMLTSRLQEAGTEVVKAKVGEGSATLSMAHAGARFVSSLLEASDGHKGLVECAFVRSEETEAAYLSTPLLLGKRGVERSMGL-QKRGVERSMGLGPLPELKAAIRDGEEFARNF 341
[Close]
BLAST of Malate dehydrogenase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002737.1 (pep scaffold:Pmarinus_7.0:GL478354:288785:313444:1 gene:ENSPMAG00000002457.1 transcript:ENSPMAT00000002737.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.2174 bits (121), Expect = 1.384e-7
Identity = 41/160 (25.62%), Postives = 83/160 (51.88%), Query Frame = 2 
Query:  200 EELALYDI--KNVKGVAVDLSH---IERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTI 664
            +E+AL D+    ++G A+DL H     +  K+ A    +   A    S + V+ AG+ +  G SR  L + N A+  ++  ++AK+ P+A++ +++NP++ ++  +A  L+ F V   + +   T L + R    + +   I  + +H  +IG H  S++
Sbjct:   47 DEVALVDVMEDKLRGEAMDLQHGSLFLKTAKIVA----DTDYAVTAGSKLCVVTAGVRQKEGESRLALVERNVAVFRKIIPNLAKYSPDAVLLIVSNPVD-ILTFVAWKLSGFPVH--RVIGSGTNLDSARLRFLMGERLGISPSSIHGYIIGEHGDSSV 199
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BLAST of Malate dehydrogenase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002689.1 (L-lactate dehydrogenase [Source:UniProtKB/Swiss-Prot;Acc:P33571])

HSP 1 Score: 46.595 bits (109), Expect = 4.075e-6
Identity = 47/191 (24.61%), Postives = 89/191 (46.60%), Query Frame = 2 
Query:  125 KVSVLGAAGGIGQPLCLFCKKTPLIEELALYDI--KNVKGVAVDLSH---IERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGI-TTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVIS 679
            KV+++G  G +G    +      L +ELAL D+    +KG  +DL H     +  K+ A    ++  +    S +VV+ AG  +  G SR +L + N  I   +  +I K+ PN ++ +++NP    V ++  +    +     ++ G    L + R    +++   ++    H  +IG H G + +PV S
Sbjct:   24 KVTIVGV-GQVGMAAAISVLLRDLADELALVDVVEDRLKGEMMDLLHGSLFLKTAKIVA----DKDYSVTAGSRLVVVTAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCILLVVSNP----VDILTYVAWKLSGLPKHRVIGSGCNLDSARFRYLMSERLGVNSASCHGWIIGEH-GDSSVPVWS 204
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BLAST of Malate dehydrogenase vs. Ensembl Yeast
Match: MDH1 (Mitochondrial malate dehydrogenase; catalyzes interconversion of malate and oxaloacetate; involved in the tricarboxylic acid (TCA) cycle; phosphorylated [Source:SGD;Acc:S000001568])

HSP 1 Score: 255.758 bits (652), Expect = 1.406e-83
Identity = 141/317 (44.48%), Postives = 204/317 (64.35%), Query Frame = 2 
Query:  122 YKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEE--LGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKS---DETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKS 1057
            YKV+VLGA GGIGQPL L  K    + +L LYD+K  KGVA DLSHI     V  F  +E   L   L  +D+V+IPAG+PR PGM+R+DLF  NA+I+ +L  + A+  PNA I +I+NP+NS VP++A++L +  V++ KKLFG+TTL +IRA  FI++ +N D T+  V VIGGHSG TIIP+ISQ+  H     ++R+ ++ +I+  G E+V+AK G GSATLSM+ A  +F N+++    G   VIE ++V S        E+FAS +  G  G+E+   IG+++  E  +L+     +K++IE G  +  S
Sbjct:   18 YKVTVLGAGGGIGQPLSLLLKLNHKVTDLRLYDLKGAKGVATDLSHIPTNSVVKGFTPEEPDGLNNALKDTDMVLIPAGVPRKPGMTRDDLFAINASIVRDLAAATAESAPNAAILVISNPVNSTVPIVAQVLKNKGVYNPKKLFGVTTLDSIRAARFISEVENTDPTQERVNVIGGHSGITIIPLISQTN-HKLMSDDKRHELIHRIQFGGDEVVKAKNGAGSATLSMAHAGAKFANAVLSGFKGERDVIEPSFVDSPLFKSEGIEFFASPVTLGPDGIEKIHPIGELSSEEEEMLQKCKETLKKNIEKGVNFVAS 333
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BLAST of Malate dehydrogenase vs. Ensembl Yeast
Match: MDH3 (Peroxisomal malate dehydrogenase; catalyzes interconversion of malate and oxaloacetate; involved in the glyoxylate cycle [Source:SGD;Acc:S000002236])

HSP 1 Score: 186.808 bits (473), Expect = 9.308e-57
Identity = 121/337 (35.91%), Postives = 188/337 (55.79%), Query Frame = 2 
Query:  125 KVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQ---------AKNIDITKLH--VPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIE--SAYV---------KSDE----TECEYFASSLLFGRQGVERNLG---IGQMTEFEISLLKAAIPAIKRDIEVGKKY 1048
            KV++LGA+GG+GQPL L  K +P + ELALYDI+  +G+  DLSHI        ++ K+ +   L  + +V+IPAG+PR PG++R+DLFK NA I+  L  ++ K  PNA I +I+NP+NSLVP+  E L     F    + G+T L  +RA TF+            +  D T +H  V VIGGHSG TIIP+I+  +   Q   +  + I  +++  G EIV+AK G GSATLSM++A  +F   ++ +        E  SA+V         K+ +       EYF+  ++  R G   ++    + +++  E  L+  A+  ++++IE GK +
Sbjct:    3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD-KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFI-HRVQFGGDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVL-RNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336
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BLAST of Malate dehydrogenase vs. Ensembl Yeast
Match: MDH2 (Cytoplasmic malate dehydrogenase; one of three isozymes that catalyze interconversion of malate and oxaloacetate; involved in the glyoxylate cycle and gluconeogenesis during growth on two-carbon compounds; interacts with Pck1p and Fbp1 [Source:SGD;Acc:S000005486])

HSP 1 Score: 174.096 bits (440), Expect = 1.638e-51
Identity = 125/367 (34.06%), Postives = 196/367 (53.41%), Query Frame = 2 
Query:  104 SLQIRTYKVSVLGAAGGIGQPLCLFCK---KTPLIE--------ELALYDIKN--VKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHC--PNALICLITNPLNSLVPLMAE--ILNHFNVFDS---KKLFGITTLSTIRAITFIAQAKNIDI-------TKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYV-------------KSDE-----TECEYFASSLLFGRQG---VERNLGIGQMTEFEIS-LLKAAIPAIKRDIEVGKKYAKS 1057
            S++  + K+++LGAAGGIGQ L L  K   +  L E         LALYD+    + GV  DLSHI+    V++      +  CL  + IVVIPAG+PR PGM+R+DLF  NA II++L  SIA+ C      + +I+NP+NSLVP+M    + NH    +S   +++ G+T L  +RA TF+ +  NI+        +   VPVIGGHSG TIIP+ SQS    +   ++   ++ +++  G E+V+AK G+GSATLSM+ A Y+ +   +    G    I   Y               +D+        +YFA  L    +G   V+ ++ + +M + E + +L   +  +K++I+ G ++  S
Sbjct:    8 SIEQDSLKIAILGAAGGIGQSLSLLLKAQLQYQLKESNRSVTHIHLALYDVNQEAINGVTADLSHIDTPISVSSHSPAGGIENCLHNASIVVIPAGVPRKPGMTRDDLFNVNAGIISQLGDSIAECCDLSKVFVLVISNPVNSLVPVMVSNILKNHPQSRNSGIERRIMGVTKLDIVRASTFLREI-NIESGLTPRVNSMPDVPVIGGHSGETIIPLFSQSNFLSRLNEDQLKYLIHRVQYGGDEVVKAKNGKGSATLSMAHAGYKCVVQFVSLLLGNIEQIHGTYYVPLKDANNFPIAPGADQLLPLVDGADYFAIPLTITTKGVSYVDYDI-VNRMNDMERNQMLPICVSQLKKNIDKGLEFVAS 372
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BLAST of Malate dehydrogenase vs. Ensembl Nematostella
Match: EDO30176 (Malate dehydrogenase [Source:UniProtKB/TrEMBL;Acc:A7T1J0])

HSP 1 Score: 340.887 bits (873), Expect = 2.151e-116
Identity = 152/308 (49.35%), Postives = 228/308 (74.03%), Query Frame = 2 
Query:  125 KVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKY 1048
            KV++LGAAGGIGQP+ L  K++PLI  LALYDI N  GVA DLSHI  + KVT+ +G ++L A L+   +V IPAG+PR PGM+R+DLF +NA+I+  L+ + AKHCP A+IC+I+NP+NS VP+ +E+     V+D  ++ G+TTL  +RA TF+A+AK +D+  + +PVIGGHSG TI+P++SQ+ P+V F  +E   + D+I+NAG+E+V AKAG GSATLSM++A   F++S+IEA  G+  V++ A++KSD TE  YFA+ ++ G  GVE+NLG+G+++++E   +   IP + ++I+ G+ +
Sbjct:   31 KVAILGAAGGIGQPMSLLLKQSPLISHLALYDIVNTPGVAADLSHISTRAKVTSHQGPDDLKAALEGCSVVAIPAGVPRKPGMTRDDLFNTNASIVKNLSEACAKHCPKAIICIISNPVNSTVPIASEVYKKAGVYDPGRILGVTTLDIVRAHTFVAEAKGLDVNNIKIPVIGGHSGVTILPLLSQTTPNVTFTQDELEKLTDRIQNAGTEVVNAKAGAGSATLSMAYAGKEFVHSVIEALNGKKDVVQCAFIKSDLTEAGYFATPVVLGTNGVEKNLGMGKLSDYEQKKMGEVIPELLKNIKKGEDF 338
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BLAST of Malate dehydrogenase vs. Ensembl Nematostella
Match: EDO33958 (Malate dehydrogenase [Source:UniProtKB/TrEMBL;Acc:A7SQS1])

HSP 1 Score: 239.965 bits (611), Expect = 4.699e-78
Identity = 113/271 (41.70%), Postives = 176/271 (64.94%), Query Frame = 2 
Query:  236 GVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKY 1048
            GVA DLSHI  + KVT+ +G ++L A L+   +V IPAG+PR PGM+R+DLF +NA+I+  L+ + AKHCP A+IC+I+NP+NS VP+ +E+     V+D  ++ G+TTL  +RA TF+A+AK                          + P V F  ++   + D+I+NAG+E+V AKAG GSATLSM++A   F++S+IEA  G+  V++ A++KS  TE  YFA+ +L G  GVE+NLG+G+++++E   +   IP + ++I+ G+ +
Sbjct:    7 GVAADLSHISTRAKVTSHQGPDDLKAALEGCSVVAIPAGVPRKPGMTRDDLFNTNASIVKNLSEACAKHCPKAIICIISNPVNSTVPIASEVYKKAGVYDPARILGVTTLDIVRAHTFVAEAK--------------------------TTPCVNFTQDDLEKLTDRIQNAGTEVVNAKAGAGSATLSMAYAGKEFVHSVIEALNGKKDVVQCAFIKSHLTEAGYFATPVLLGTNGVEKNLGMGKLSDYEQKKMGEVIPELLKNIKKGEDF 251
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BLAST of Malate dehydrogenase vs. Ensembl Medaka
Match: mdh2 (malate dehydrogenase 2, NAD (mitochondrial) [Source:ZFIN;Acc:ZDB-GENE-040426-2143])

HSP 1 Score: 345.51 bits (885), Expect = 2.212e-117
Identity = 154/309 (49.84%), Postives = 232/309 (75.08%), Query Frame = 2 
Query:  125 KVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYA 1051
            KV+VLGA+GGIGQPL L  K +PL+  L+LYDI +  GVA DLSHIE + +VT + G ++L A L   ++VVIPAG+PR PGM+R+DLF +NA I+A L  + A++CP A+IC+I NP+NS +P+ +E++    V++  ++FG+TTL  +RA TF+A+ K +D  +++VPVIGGH+G TIIP+ISQ  P V+FP ++ + +  +I+ AG+E+V+AKAG GSATLSM++A  RF  S+++A  G+ GV+E A+V+S+ETEC+YF++ LL G+ G+E+NLG+G+++ FE  L+  AI  +K  I+ G+ +A
Sbjct:   52 KVAVLGASGGIGQPLSLLLKNSPLVSHLSLYDIAHTPGVAADLSHIETRAQVTGYMGPDQLDAALQGCEVVVIPAGVPRKPGMTRDDLFNTNATIVATLADACARNCPEAMICIIANPVNSTIPITSEVMKKHGVYNPNRVFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVEFPADQLSALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFTFSVLDAMNGKEGVVECAFVRSEETECKYFSTPLLLGKSGIEKNLGLGKLSAFEEKLVADAIGELKASIKKGEDFA 360
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BLAST of Malate dehydrogenase vs. Ensembl Medaka
Match: ENSORLT00000012534.2 (L-lactate dehydrogenase B chain [Source:NCBI gene;Acc:101165776])

HSP 1 Score: 51.2174 bits (121), Expect = 7.344e-7
Identity = 47/166 (28.31%), Postives = 78/166 (46.99%), Query Frame = 2 
Query:  194 LIEELALYDI--KNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEI--LNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVIS 679
            L +ELAL D+    +KG  +DL H     K +     ++  A    S +VV+ AG+ +  G SR +L + N  +   +   I K+ PN  I +++NP++ L  +  ++  L    V  S      T L + R    +A+   I  +  +  V+G H G T +PV S
Sbjct:   45 LCDELALVDVMEDRLKGEMMDLQHGSLFLKTSKIVADKDY-AVTANSRLVVVTAGVRQQEGESRLNLVQRNVNVFKAIIPQIIKYSPNCTIVVVSNPVDVLTYVTWKLSGLPKHRVIGSG-----TNLDSARFRYLMAERLGIHASSFNGWVLGEH-GDTSVPVWS 203
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BLAST of Malate dehydrogenase vs. Planmine SMEST
Match: SMESG000035456.1 (SMESG000035456.1)

HSP 1 Score: 697.582 bits (1799), Expect = 0.000e+0
Identity = 341/341 (100.00%), Postives = 341/341 (100.00%), Query Frame = 2 
Query:   56 MLQSFNKSVLFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKSYLSMLNK 1078
            MLQSFNKSVLFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKSYLSMLNK
Sbjct:    1 MLQSFNKSVLFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKSYLSMLNK 341
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BLAST of Malate dehydrogenase vs. Planmine SMEST
Match: SMESG000008924.1 (SMESG000008924.1)

HSP 1 Score: 356.295 bits (913), Expect = 3.616e-122
Identity = 173/326 (53.07%), Postives = 237/326 (72.70%), Query Frame = 2 
Query:   83 LFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKSY 1060
            +FR S  + Q    KV+VLGA+GGIGQP+ L  KK+  ++ LALYD+ +VKGVA DLSHIE    VT + G  EL  CL  SD+VVIPAG+PR PGM+R+DLF +NA+I+A+L    A+ CP A+IC+ITNP+NS VP+ AEIL     +D+++LFG+TTL  +R+ TFIA+AK +D+TK+ VPVIGGHSG TIIPVISQ+ P V FP  E N +  +I+NAG+E+VEAKAG GSATLSM++A  RF+  ++ A  G   +IE A+V+S+ TE ++FA+ LL G  G+E+NLG+  +T FE  L+K A+P +  +I+ G ++A  Y
Sbjct:   12 VFR-SFSTCQALNAKVAVLGASGGIGQPMSLLLKKSSAVDRLALYDVAHVKGVAADLSHIETPAVVTGYLGPGELLECLKNSDVVVIPAGVPRKPGMTRDDLFNTNASIVADLVHGCAQACPKAMICIITNPVNSTVPIAAEILKKAGCYDARRLFGVTTLDIVRSNTFIAEAKLLDVTKMSVPVIGGHSGVTIIPVISQAIPSVSFPESEINKLTIRIQNAGTEVVEAKAGAGSATLSMAYAGVRFVKRILAAMKGNKNIIECAFVESNVTEAKFFANPLLLGPNGIEKNLGLPDLTAFEKELIKKAMPELLANIKNGIEFANKY 336
[Close]
BLAST of Malate dehydrogenase vs. Planmine SMEST
Match: SMESG000008151.1 (SMESG000008151.1)

HSP 1 Score: 311.612 bits (797), Expect = 1.835e-104
Identity = 153/328 (46.65%), Postives = 230/328 (70.12%), Query Frame = 2 
Query:  110 QIRTY--------KVSVLGAAGGIGQPLCLFCKKTPLIEELALYDIKNVKGVAVDLSHIERKGKVTAFEGKEE-LGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMSWAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERNLGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKSYLS 1066
            Q RT+        KV+VLGA G IGQPL L  K +  + ELALYDIK+V GVA DLSHI ++ K+T      E L  C+  S IVVI AG  RN  M+R DLF +NA+I++ L    A   P  ++C++TNP++SLVP++A+I    +V+D  +LFG+T+L+++RA TF+AQAK +  TKL+VPVIGG+S +T+IP+ISQ  P + FP ++R  +  +I++AG+EI EAKAG+GSATLS +++ ++FI SLI+   G+ GV++ AYV+S    CE+FA+ ++ G  G+ + +G G++ ++E+SL++AAIP ++  I+ GK++A  Y+S
Sbjct:   12 QTRTFHLSSLNNVKVAVLGANGAIGQPLSLLLKDSISVTELALYDIKSVAGVAADLSHISKRAKITGTSSSPEGLSECIKDSKIVVIVAGRSRNLDMTRFDLFTTNASIVSSLAHQCAIVNPQCMLCIVTNPIDSLVPMVAQIFKSLSVYDPCRLFGVTSLNSVRASTFVAQAKGLIGTKLYVPVIGGNSENTLIPLISQCIPPLSFPPKQRIELTRRIQSAGTEINEAKAGKGSATLSTAYSTFKFITSLIDGMDGKKGVVQCAYVESTRGPCEFFATPIVLGMNGIHKIIGAGRLIDYELSLIEAAIPELQESIKTGKEFAAQYIS 339
[Close]
BLAST of Malate dehydrogenase vs. Planmine SMEST
Match: SMESG000036898.1 (SMESG000036898.1)

HSP 1 Score: 64.3142 bits (155), Expect = 2.723e-11
Identity = 56/202 (27.72%), Postives = 95/202 (47.03%), Query Frame = 2 
Query:   83 LFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEELALYDI--KNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGI-TTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTIIPVIS 679
            L +  C+S      K+S++G  G +G           +  EL L D+  + +KG  +DL H ++     A  G  +     +KSDIV+I AG  +  G SR +L + N  +   + + + KH P  +I +++NP    V +++ +    + F   K+FG  T L + R    + Q   +  T +H  +IG H G   +PV S
Sbjct:   15 LAKFGCKS------KISIVGI-GSVGMASAYTILVQGICGELVLVDVSEERIKGEVMDLVHGQQFLPSCAIYGGTDY-KLTEKSDIVIICAGARQREGESRLNLVQRNVDVFKNIIIPVIKHSPECMIIVVSNP----VDILSYVAWKISGFPRSKVFGTGTMLDSARFRYLLGQKLGVSPTSIHGYIIGEH-GDHSVPVWS 203
[Close]
BLAST of Malate dehydrogenase vs. Planmine SMEST
Match: SMESG000005325.1 (SMESG000005325.1)

HSP 1 Score: 56.6102 bits (135), Expect = 1.037e-8
Identity = 50/186 (26.88%), Postives = 91/186 (48.92%), Query Frame = 2 
Query:  125 KVSVLGAAGGIGQPLCLFCKKTPLIEELALYDI--KNVKGVAVDLSHIER---KGKVTAFEGKEELGACLDKSDIVVIPAGLPRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMAEILNHFNVFDSKKLFGI-TTLSTIRAITFIAQAKNIDITKLHVPVIGGHSGSTI 664
            K++V+G  G +G           + +ELAL D+    ++G  +DL H ++   K K+TA     +  A ++ S+IV++ AG  +  G +R +L + N  I   +   I  + PN +I ++ NP    V ++A +    + F   ++FG  T L + R   F+ +   I+    H  +IG H  S++
Sbjct:   23 KITVVGC-GQVGMAAAFSILVQNICKELALIDVCEDRLQGEMMDLQHGQQFVSKCKITA---SSDYSASVN-SNIVIVTAGARQREGETRLNLVQRNVDIFKAIIPKIVHNSPNCIIIVVANP----VDILAYVAWKISGFPKNRVFGSGTMLDSARFRFFLGEKLGINPKSCHGYIIGEHGDSSV 199
The following BLAST results are available for this feature:
BLAST of Malate dehydrogenase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MDH26.898e-12450.46malate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGN... [more]
MDH23.240e-10044.95malate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGN... [more]
MDH29.078e-8649.34malate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGN... [more]
LDHA7.172e-725.96lactate dehydrogenase A [Source:HGNC Symbol;Acc:HG... [more]
LDHA7.172e-725.96lactate dehydrogenase A [Source:HGNC Symbol;Acc:HG... [more]
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BLAST of Malate dehydrogenase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mdh-26.665e-10446.65Probable malate dehydrogenase, mitochondrial [Sou... [more]
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BLAST of Malate dehydrogenase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Mdh23.277e-11250.32gene:FBgn0262559 transcript:FBtr0083563[more]
CG107495.259e-10146.86gene:FBgn0036328 transcript:FBtr0075871[more]
CG107485.671e-8944.03gene:FBgn0036327 transcript:FBtr0075900[more]
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BLAST of Malate dehydrogenase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mdh21.087e-11649.35malate dehydrogenase 2, NAD (mitochondrial) [Sourc... [more]
ldha2.437e-626.67lactate dehydrogenase A4 [Source:NCBI gene;Acc:304... [more]
ldha2.437e-626.67lactate dehydrogenase A4 [Source:NCBI gene;Acc:304... [more]
ldhbb4.807e-627.81lactate dehydrogenase Bb [Source:NCBI gene;Acc:436... [more]
ldhbb6.148e-627.81lactate dehydrogenase Bb [Source:NCBI gene;Acc:436... [more]
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BLAST of Malate dehydrogenase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sssca11.003e-12150.30Sjogren syndrome/scleroderma autoantigen 1 [Source... [more]
sssca14.096e-12151.45Sjogren syndrome/scleroderma autoantigen 1 [Source... [more]
sssca14.277e-12151.45Sjogren syndrome/scleroderma autoantigen 1 [Source... [more]
sssca14.482e-12151.45Sjogren syndrome/scleroderma autoantigen 1 [Source... [more]
sssca15.517e-12150.00Sjogren syndrome/scleroderma autoantigen 1 [Source... [more]
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BLAST of Malate dehydrogenase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Mdh21.994e-12250.00malate dehydrogenase 2, NAD (mitochondrial) [Sourc... [more]
Mdh26.682e-6352.10malate dehydrogenase 2, NAD (mitochondrial) [Sourc... [more]
Mdh21.087e-4144.23malate dehydrogenase 2, NAD (mitochondrial) [Sourc... [more]
Ldhal6b9.068e-726.06lactate dehydrogenase A-like 6B [Source:MGI Symbol... [more]
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BLAST of Malate dehydrogenase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5NVR2|MDHM_PONAB2.261e-12350.46Malate dehydrogenase, mitochondrial OS=Pongo abeli... [more]
sp|P40926|MDHM_HUMAN3.312e-12350.46Malate dehydrogenase, mitochondrial OS=Homo sapien... [more]
sp|P04636|MDHM_RAT2.410e-12249.70Malate dehydrogenase, mitochondrial OS=Rattus norv... [more]
sp|Q32LG3|MDHM_BOVIN5.642e-12249.69Malate dehydrogenase, mitochondrial OS=Bos taurus ... [more]
sp|P00346|MDHM_PIG1.171e-12149.69Malate dehydrogenase, mitochondrial OS=Sus scrofa ... [more]
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BLAST of Malate dehydrogenase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
G4VBJ01.188e-13457.40Malate dehydrogenase OS=Schistosoma mansoni OX=618... [more]
A0A430QMD71.446e-13457.10Malate dehydrogenase OS=Schistosoma bovis OX=6184 ... [more]
A0A183LL111.446e-13457.10Malate dehydrogenase OS=Schistosoma margrebowiei O... [more]
Q5D9T15.729e-13356.50Malate dehydrogenase OS=Schistosoma japonicum OX=6... [more]
C1LJM54.365e-13256.19Malate dehydrogenase OS=Schistosoma japonicum OX=6... [more]
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BLAST of Malate dehydrogenase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
mdh21.283e-11750.81malate dehydrogenase 2 [Source:NCBI gene;Acc:10303... [more]
ldhba2.342e-627.71lactate dehydrogenase B [Source:NCBI gene;Acc:1030... [more]
ldhbb2.392e-626.79L-lactate dehydrogenase B-B chain [Source:NCBI gen... [more]
ldha3.901e-626.67L-lactate dehydrogenase A chain [Source:NCBI gene;... [more]
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BLAST of Malate dehydrogenase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
mdh21.023e-9945.92malate dehydrogenase 2, NAD (mitochondrial) [Sourc... [more]
ENSPMAT00000002737.11.384e-725.63pep scaffold:Pmarinus_7.0:GL478354:288785:313444:1... [more]
ENSPMAT00000002689.14.075e-624.61L-lactate dehydrogenase [Source:UniProtKB/Swiss-P... [more]
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BLAST of Malate dehydrogenase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
MDH11.406e-8344.48Mitochondrial malate dehydrogenase; catalyzes inte... [more]
MDH39.308e-5735.91Peroxisomal malate dehydrogenase; catalyzes interc... [more]
MDH21.638e-5134.06Cytoplasmic malate dehydrogenase; one of three iso... [more]
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BLAST of Malate dehydrogenase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO301762.151e-11649.35Malate dehydrogenase [Source:UniProtKB/TrEMBL;Acc... [more]
EDO339584.699e-7841.70Malate dehydrogenase [Source:UniProtKB/TrEMBL;Acc... [more]
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BLAST of Malate dehydrogenase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
mdh22.212e-11749.84malate dehydrogenase 2, NAD (mitochondrial) [Sourc... [more]
ENSORLT00000012534.27.344e-728.31L-lactate dehydrogenase B chain [Source:NCBI gene;... [more]
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BLAST of Malate dehydrogenase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000035456.10.000e+0100.00SMESG000035456.1[more]
SMESG000008924.13.616e-12253.07SMESG000008924.1[more]
SMESG000008151.11.835e-10446.65SMESG000008151.1[more]
SMESG000036898.12.723e-1127.72SMESG000036898.1[more]
SMESG000005325.11.037e-826.88SMESG000005325.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010208 ID=SMED30010208|Name=Malate dehydrogenase|organism=Schmidtea mediterranea sexual|type=transcript|length=1099bp
GGTCAGTGTTTTAAACTATCGGTTTCATTATAATTTAAAATTGGAATTTT
AAATTATGTTGCAATCTTTTAACAAATCTGTATTATTTCGCAATTCTTGC
AGGAGTTTGCAGATTAGGACATATAAAGTATCAGTTCTTGGCGCTGCTGG
TGGTATCGGTCAGCCATTGTGCCTGTTTTGTAAAAAAACTCCATTGATTG
AGGAACTAGCTTTATATGATATAAAAAATGTCAAAGGAGTTGCAGTTGAT
TTATCACACATTGAACGCAAGGGAAAAGTCACAGCATTTGAAGGGAAAGA
AGAATTAGGGGCTTGTCTAGATAAATCAGACATTGTTGTTATTCCAGCAG
GTCTCCCCAGAAACCCAGGAATGAGTAGAAATGATTTATTTAAATCTAAT
GCCGCAATTATTGCCGAACTTACTGTGAGTATAGCCAAACATTGTCCAAA
TGCTCTCATCTGTCTCATAACAAATCCATTAAACAGTCTTGTTCCACTAA
TGGCAGAAATATTAAATCATTTCAATGTTTTTGACTCTAAAAAGCTGTTT
GGCATTACTACTTTATCAACTATTCGTGCCATTACATTTATTGCACAAGC
AAAAAATATCGACATTACCAAATTGCATGTTCCTGTTATTGGGGGGCATT
CAGGAAGCACAATTATCCCAGTCATTTCTCAAAGTGCTCCACATGTTCAA
TTTCCACTGGAAGAACGTAATATGATTGTTGATAAGATCAGAAATGCTGG
TTCAGAAATTGTGGAAGCCAAAGCAGGACAAGGATCGGCCACATTGAGTA
TGTCATGGGCTGCTTATCGTTTTATAAATTCATTAATTGAAGCAAGAGGC
GGACGTACCGGGGTTATCGAATCAGCTTATGTTAAATCTGACGAAACAGA
ATGTGAATATTTTGCGTCTTCATTGCTATTTGGGAGACAGGGAGTCGAAC
GGAACCTCGGTATTGGTCAAATGACGGAATTCGAAATATCACTGCTAAAA
GCGGCGATTCCAGCAATCAAGAGAGATATTGAAGTAGGAAAGAAATACGC
TAAATCATATTTGTCTATGTTAAATAAATAAAAAATCTGTTTGTGTGAG
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protein sequence of SMED30010208-orf-1

>SMED30010208-orf-1 ID=SMED30010208-orf-1|Name=SMED30010208-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=342bp
MLQSFNKSVLFRNSCRSLQIRTYKVSVLGAAGGIGQPLCLFCKKTPLIEE
LALYDIKNVKGVAVDLSHIERKGKVTAFEGKEELGACLDKSDIVVIPAGL
PRNPGMSRNDLFKSNAAIIAELTVSIAKHCPNALICLITNPLNSLVPLMA
EILNHFNVFDSKKLFGITTLSTIRAITFIAQAKNIDITKLHVPVIGGHSG
STIIPVISQSAPHVQFPLEERNMIVDKIRNAGSEIVEAKAGQGSATLSMS
WAAYRFINSLIEARGGRTGVIESAYVKSDETECEYFASSLLFGRQGVERN
LGIGQMTEFEISLLKAAIPAIKRDIEVGKKYAKSYLSMLNK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR010097Malate_DH_type1
IPR036291NAD(P)-bd_dom_sf
IPR015955Lactate_DH/Glyco_Ohase_4_C
IPR022383Lactate/malate_DH_C
IPR001557L-lactate/malate_DH
IPR016040NAD(P)-bd_dom
IPR001236Lactate/malate_DH_N
Vocabulary: biological process
TermDefinition
GO:0055114oxidation-reduction process
GO:0005975carbohydrate metabolic process
GO:0019752carboxylic acid metabolic process
GO:0006099tricarboxylic acid cycle
GO:0006108malate metabolic process
Vocabulary: molecular function
TermDefinition
GO:0016491oxidoreductase activity
GO:0003824catalytic activity
GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016615malate dehydrogenase activity
GO:0030060L-malate dehydrogenase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001236Lactate/malate dehydrogenase, N-terminalPFAMPF00056Ldh_1_Ncoord: 24..166
e-value: 1.2E-38
score: 132.3
NoneNo IPR availableGENE3DG3DSA:3.40.50.720coord: 17..167
e-value: 1.2E-58
score: 199.3
NoneNo IPR availablePANTHERPTHR11540MALATE AND LACTATE DEHYDROGENASEcoord: 16..333
NoneNo IPR availableCDDcd01337MDH_glyoxysomal_mitochondrialcoord: 23..332
e-value: 4.46563E-169
score: 470.818
IPR010097Malate dehydrogenase, type 1TIGRFAMTIGR01772TIGR01772coord: 24..333
e-value: 6.5E-117
score: 388.2
IPR001557L-lactate/malate dehydrogenasePIRSFPIRSF000102Lac_mal_DHcoord: 19..335
e-value: 2.9E-53
score: 178.6
IPR022383Lactate/malate dehydrogenase, C-terminalPFAMPF02866Ldh_1_Ccoord: 168..330
e-value: 3.0E-39
score: 134.6
IPR015955Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminalGENE3DG3DSA:3.90.110.10coord: 168..334
e-value: 1.9E-54
score: 186.1
IPR015955Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminalSUPERFAMILYSSF56327LDH C-terminal domain-likecoord: 168..333
IPR036291NAD(P)-binding domain superfamilySUPERFAMILYSSF51735NAD(P)-binding Rossmann-fold domainscoord: 24..166