Placenta-specific gene 8 protein

Overview
NamePlacenta-specific gene 8 protein
Smed IDSMED30010206
Length (bp)618
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Placenta-specific gene 8 protein (SMED30010206) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Placenta-specific gene 8 protein (SMED30010206) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30010206

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
tail regionSMED30010206SMESG000050245.1 SMESG000050244.1 SmedASXL_066692SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
protonephridiaSMED30010206SMESG000050245.1 SMESG000050244.1 dd_Smed_v4_6151_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30010206SMESG000050245.1 SMESG000050244.1 dd_Smed_v4_6151_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30010206SMESG000050245.1 SMESG000050244.1 dd_Smed_v4_6151_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30010206SMESG000050245.1 SMESG000050244.1 dd_Smed_v4_6151_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30010206SMESG000050245.1 SMESG000050244.1 dd_Smed_v4_6151_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Human
Match: PLAC8L1 (PLAC8 like 1 [Source:HGNC Symbol;Acc:HGNC:31746])

HSP 1 Score: 68.1662 bits (165), Expect = 6.238e-14
Identity = 40/115 (34.78%), Postives = 58/115 (50.43%), Query Frame = 3 
Query:  126 TTVFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 470
             +  V QP +G    T    I + T   WS+GLF  C D   C+C  FCP C  C +   Y E +C PL  P ST  LR   R R+ I+G++  D    + C+  ++CQ+ R++ 
Sbjct:   45 ASAVVKQPVRGASGRTTITAIVQ-TGGGWSTGLFSVCRDRRICFCGLFCPMCLECDIARHYGECLCWPLL-PGSTFALRIGTRERHKIQGTLCEDWLAVHCCWAFSICQVARELK 157
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Human
Match: CNFN (cornifelin [Source:HGNC Symbol;Acc:HGNC:30183])

HSP 1 Score: 65.855 bits (159), Expect = 1.491e-13
Identity = 38/109 (34.86%), Postives = 54/109 (49.54%), Query Frame = 3 
Query:  168 ITRQNQIA-----EPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVE 479
            +T Q Q A     +    +W +GL DCC+D   C C TF P C  C +   + E  C P + P     +RT  R R HI+GS+  D     +C  CA+CQ+ R++   E
Sbjct:    5 VTSQPQCATTSCYQTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCAP-YLPGGLHSIRTGMRERYHIQGSVGHDWAALTFCLPCALCQMARELKIRE 112
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Human
Match: CNFN (cornifelin [Source:HGNC Symbol;Acc:HGNC:30183])

HSP 1 Score: 65.855 bits (159), Expect = 1.491e-13
Identity = 38/109 (34.86%), Postives = 54/109 (49.54%), Query Frame = 3 
Query:  168 ITRQNQIA-----EPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVE 479
            +T Q Q A     +    +W +GL DCC+D   C C TF P C  C +   + E  C P + P     +RT  R R HI+GS+  D     +C  CA+CQ+ R++   E
Sbjct:    5 VTSQPQCATTSCYQTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCAP-YLPGGLHSIRTGMRERYHIQGSVGHDWAALTFCLPCALCQMARELKIRE 112
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Human
Match: PLAC8 (placenta associated 8 [Source:HGNC Symbol;Acc:HGNC:19254])

HSP 1 Score: 61.2326 bits (147), Expect = 8.060e-12
Identity = 41/115 (35.65%), Postives = 55/115 (47.83%), Query Frame = 3 
Query:  129 TVFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYE-FVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 470
             V VTQPG G            P   NW +G+ DC  DC  C C TFC  C  C +     E  +C       +++ +RT +R+R  I GSI  D   T  C  C +CQ+KRD++
Sbjct:    7 VVVVTQPGVGPGP--------APQNSNWQTGMCDCFSDCGVCLCGTFCFPCLGCQVAADMNECCLC------GTSVAMRTLYRTRYGIPGSICDDYMATLCCPHCTLCQIKRDIN 107
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Human
Match: PLAC8 (placenta associated 8 [Source:HGNC Symbol;Acc:HGNC:19254])

HSP 1 Score: 61.2326 bits (147), Expect = 8.060e-12
Identity = 41/115 (35.65%), Postives = 55/115 (47.83%), Query Frame = 3 
Query:  129 TVFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYE-FVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 470
             V VTQPG G            P   NW +G+ DC  DC  C C TFC  C  C +     E  +C       +++ +RT +R+R  I GSI  D   T  C  C +CQ+KRD++
Sbjct:    7 VVVVTQPGVGPGP--------APQNSNWQTGMCDCFSDCGVCLCGTFCFPCLGCQVAADMNECCLC------GTSVAMRTLYRTRYGIPGSICDDYMATLCCPHCTLCQIKRDIN 107
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Zebrafish
Match: ponzr5 (plac8 onzin related protein 5 [Source:ZFIN;Acc:ZDB-GENE-081104-325])

HSP 1 Score: 69.3218 bits (168), Expect = 5.025e-15
Identity = 46/123 (37.40%), Postives = 62/123 (50.41%), Query Frame = 3 
Query:  144 QPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPL-----FTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYL 497
            QPGQ          IA+ T   WSSG+ DCCD+   C    +C  C+ C     + E +C PL     F PA TL +R   RSR  IKGSI  DC  + +C  C+ CQ+ R+M+  E    ++
Sbjct:    5 QPGQ--------FMIAQ-TNDQWSSGICDCCDNVPECCFSFWCFPCFACSTARKHGECLCLPLLDGFGFIPAITLAMRVSVRSRYGIKGSICKDCAYSTFCGACSWCQISREMNIREQSLTFV 118
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Zebrafish
Match: ponzr5 (plac8 onzin related protein 5 [Source:ZFIN;Acc:ZDB-GENE-081104-325])

HSP 1 Score: 69.3218 bits (168), Expect = 5.343e-15
Identity = 46/123 (37.40%), Postives = 62/123 (50.41%), Query Frame = 3 
Query:  144 QPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPL-----FTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYL 497
            QPGQ          IA+ T   WSSG+ DCCD+   C    +C  C+ C     + E +C PL     F PA TL +R   RSR  IKGSI  DC  + +C  C+ CQ+ R+M+  E    ++
Sbjct:    8 QPGQ--------FMIAQ-TNDQWSSGICDCCDNVPECCFSFWCFPCFACSTARKHGECLCLPLLDGFGFIPAITLAMRVSVRSRYGIKGSICKDCAYSTFCGACSWCQISREMNIREQSLTFV 121
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Zebrafish
Match: plac8l1 (PLAC8 like 1 [Source:ZFIN;Acc:ZDB-GENE-091204-165])

HSP 1 Score: 68.5514 bits (166), Expect = 1.898e-14
Identity = 42/111 (37.84%), Postives = 56/111 (50.45%), Query Frame = 3 
Query:  135 FVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDM 467
             +TQPG G    T        T  +WS+GLFD C D ++    TF P C    + H Y E +C PL  P ST  +R   R R  I+G++  D    Y CY  A+CQ+ R+M
Sbjct:   23 VLTQPGLGETTTTVTTVTQ--TGGDWSTGLFDVCGDASTLLMGTFVPCCLDLSLAHQYGECMCLPLL-PGSTFAMRVGIRERFKIRGNVCEDWMTVYCCYPLALCQMIREM 130
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Zebrafish
Match: plac8l1 (PLAC8 like 1 [Source:ZFIN;Acc:ZDB-GENE-091204-165])

HSP 1 Score: 68.1662 bits (165), Expect = 2.605e-14
Identity = 41/110 (37.27%), Postives = 55/110 (50.00%), Query Frame = 3 
Query:  138 VTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDM 467
            +TQPG G    T           +WS+GLFD C D ++    TF P C    + H Y E +C PL  P ST  +R   R R  I+G++  D    Y CY  A+CQ+ R+M
Sbjct:   29 LTQPGLGETTTTVTTVTQTGG--DWSTGLFDVCGDASTLLMGTFVPCCLDLSLAHQYGECMCLPLL-PGSTFAMRVGIRERFKIRGNVCEDWMTVYCCYPLALCQMIREM 135
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Zebrafish
Match: ponzr6 (plac8 onzin related protein 6 [Source:ZFIN;Acc:ZDB-GENE-081104-326])

HSP 1 Score: 63.929 bits (154), Expect = 1.167e-12
Identity = 39/113 (34.51%), Postives = 55/113 (48.67%), Query Frame = 3 
Query:  162 QAITRQNQIAEPT----YRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFT-------PASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDM 467
            QA++ Q  +   T       WSSG+ DCC+D + C C  +C  C +C     + E +C PL            TL +R+  R R HI+GSI  DCC    C  C  CQ+ R++
Sbjct:    4 QAVSVQPAMVVATDNVKLNQWSSGVCDCCEDMSICCCGFWCAYCLMCKTSEDFGECLCLPLLEICFGGMLHPITLAMRSSMRERYHIRGSIQDDCCAATCCPVCVWCQMAREL 116
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Xenopus
Match: myo19 (myosin XIX [Source:Xenbase;Acc:XB-GENE-999897])

HSP 1 Score: 67.3958 bits (163), Expect = 3.196e-14
Identity = 40/109 (36.70%), Postives = 56/109 (51.38%), Query Frame = 3 
Query:  159 NQAITRQNQIAEPTYRN-----WSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 470
            +QAI+ Q Q A P   N     W+S +FDCC D   C C TF P C  C +   Y E  C P+    + + +RT  R R  I G+I  DC    +C  C +CQ+ R+++
Sbjct:    2 SQAISSQPQ-AVPGCTNSNTNRWNSDVFDCCQDLGICLCGTFLPLCLACKVAQDYGECCCLPVLN-GTIIAMRTGIRERYQIPGTICNDCVCLTFCGPCTLCQMARELN 108
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Xenopus
Match: ifi35 (interferon induced protein 35 [Source:Xenbase;Acc:XB-GENE-1010748])

HSP 1 Score: 66.6254 bits (161), Expect = 8.153e-14
Identity = 43/124 (34.68%), Postives = 56/124 (45.16%), Query Frame = 3 
Query:   99 RYGCFNSPMTTVFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 470
            R  C     T   + QP Q  Q  T         +  W+S  FDC  D   C C  F P C  C +   Y E  C PL    + L LRT  R R HI+G+I  DC    +C  CA+CQ+ R+++
Sbjct:    8 RITCSQLETTQTVIFQP-QAVQGYTTSK------FGQWNSDTFDCFRDVGICLCGAFFPMCVACKVAQDYGECCCLPLM-GGTILALRTGIRERYHIQGTICTDCLCVTFCGPCALCQMARELE 123
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Xenopus
Match: ENSXETT00000008293.1 (novel protein similar to cornifelin [Source:NCBI gene;Acc:733751])

HSP 1 Score: 66.2402 bits (160), Expect = 9.889e-14
Identity = 40/120 (33.33%), Postives = 54/120 (45.00%), Query Frame = 3 
Query:  111 FNSPMTTVFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 470
              +  T +F  Q  QG              +  W+S  FDC  D   C C  F P C  C +   Y E  C PL    + L LRT  R R HI+G+I  DC    +C  CA+CQ+ R+++
Sbjct:    4 LETTQTVIFQPQAVQG---------YTTSKFGQWNSDTFDCFRDVGICLCGAFFPMCVACKVAQDYGECCCLPLMG-GTILALRTGIRERYHIQGTICTDCLCVTFCGPCALCQMARELE 113
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Xenopus
Match: ifi35 (interferon induced protein 35 [Source:Xenbase;Acc:XB-GENE-1010748])

HSP 1 Score: 65.855 bits (159), Expect = 1.505e-13
Identity = 35/90 (38.89%), Postives = 47/90 (52.22%), Query Frame = 3 
Query:  201 YRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 470
            +  W+S  FDC  D   C C  F P C  C +   Y E  C PL    + L LRT  R R HI+G+I  DC    +C  CA+CQ+ R+++
Sbjct:   33 FGQWNSDTFDCFRDVGICLCGAFFPMCVACKVAQDYGECCCLPLMG-GTILALRTGIRERYHIQGTICTDCLCVTFCGPCALCQMARELE 121
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Xenopus
Match: abtb1 (ankyrin repeat and BTB (POZ) domain containing 1 [Source:Xenbase;Acc:XB-GENE-976579])

HSP 1 Score: 60.077 bits (144), Expect = 1.735e-11
Identity = 42/116 (36.21%), Postives = 55/116 (47.41%), Query Frame = 3 
Query:  123 MTTVFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTP-LFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDM 467
            M+     QP QG Q     N         W+S +FDCC+D   C C TF P    C +   + E  C P LF   S L +RT  R R HI+GSI  D     +C  C +CQ+ R++
Sbjct:    1 MSYPIGAQP-QGVQGYVTSNS------SQWNSDVFDCCEDMGICLCGTFVPCILACKVSQDFGECCCLPCLF--GSVLAVRTGIRERYHIEGSICNDWVCLSFCGQCTLCQMAREL 107
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Mouse
Match: Cnfn (cornifelin [Source:MGI Symbol;Acc:MGI:1919633])

HSP 1 Score: 68.9366 bits (167), Expect = 6.773e-15
Identity = 40/108 (37.04%), Postives = 55/108 (50.93%), Query Frame = 3 
Query:  168 ITRQNQIAEPTYR----NWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVE 479
            +T Q Q A   Y+    +W +GL DCC+D   C C TF P C  C +   + E  C P + P     LRT  R R HI+GS+  D     +C  CA+CQ+ R++   E
Sbjct:    5 VTSQPQCANTCYQTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCAP-YLPGGLHSLRTGMRERYHIQGSVGHDWAALTFCLPCALCQMARELKIRE 111
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Mouse
Match: Cnfn (cornifelin [Source:MGI Symbol;Acc:MGI:1919633])

HSP 1 Score: 68.9366 bits (167), Expect = 8.821e-15
Identity = 40/108 (37.04%), Postives = 55/108 (50.93%), Query Frame = 3 
Query:  168 ITRQNQIAEPTYR----NWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVE 479
            +T Q Q A   Y+    +W +GL DCC+D   C C TF P C  C +   + E  C P + P     LRT  R R HI+GS+  D     +C  CA+CQ+ R++   E
Sbjct:   18 VTSQPQCANTCYQTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCAP-YLPGGLHSLRTGMRERYHIQGSVGHDWAALTFCLPCALCQMARELKIRE 124
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Mouse
Match: Plac8l1 (PLAC8-like 1 [Source:MGI Symbol;Acc:MGI:1916651])

HSP 1 Score: 67.781 bits (164), Expect = 6.477e-14
Identity = 40/113 (35.40%), Postives = 59/113 (52.21%), Query Frame = 3 
Query:  132 VFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 470
            V V QP +G    T    I + T  +WS+GLF  C D   C+    CP C  C +   Y E +C PL  P ST  LR   R R+ I+G++  DC + + C+  ++CQ+ R++ 
Sbjct:   47 VVVKQPIRGAIGRTTVAAIVQ-TGGDWSTGLFSVCRDRKICFWGLLCPMCLECDIARHYGECLCWPLL-PGSTFALRIGTRERHRIQGTLCEDCVVVHCCWPFSICQVARELK 157
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Mouse
Match: Plac8 (placenta-specific 8 [Source:MGI Symbol;Acc:MGI:2445289])

HSP 1 Score: 65.855 bits (159), Expect = 1.024e-13
Identity = 44/123 (35.77%), Postives = 60/123 (48.78%), Query Frame = 3 
Query:  129 TVFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEF-VCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGY 494
            TV VTQPG           +  P   NW + L DC  DC  C C TFC  C  C +     E  +C       +T+ +RT +R+R  I GSI  D  +T +C  C++CQLKRD++     N +
Sbjct:    6 TVIVTQPGF----------VRAPQNSNWQTSLCDCFSDCGVCLCGTFCFTCLGCQVAADMNECCLC------GTTVAMRTLYRTRYGIPGSICDDYMVTLFCPVCSVCQLKRDINRRRAMNAF 112
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Mouse
Match: Plac8 (placenta-specific 8 [Source:MGI Symbol;Acc:MGI:2445289])

HSP 1 Score: 65.855 bits (159), Expect = 1.024e-13
Identity = 44/123 (35.77%), Postives = 60/123 (48.78%), Query Frame = 3 
Query:  129 TVFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEF-VCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGY 494
            TV VTQPG           +  P   NW + L DC  DC  C C TFC  C  C +     E  +C       +T+ +RT +R+R  I GSI  D  +T +C  C++CQLKRD++     N +
Sbjct:    6 TVIVTQPGF----------VRAPQNSNWQTSLCDCFSDCGVCLCGTFCFTCLGCQVAADMNECCLC------GTTVAMRTLYRTRYGIPGSICDDYMVTLFCPVCSVCQLKRDINRRRAMNAF 112
[Close]
BLAST of Placenta-specific gene 8 protein vs. UniProt/SwissProt
Match: sp|Q0VBW2|CNFN_BOVIN (Cornifelin OS=Bos taurus OX=9913 GN=CNFN PE=3 SV=1)

HSP 1 Score: 68.9366 bits (167), Expect = 4.003e-14
Identity = 41/108 (37.96%), Postives = 55/108 (50.93%), Query Frame = 3 
Query:  168 ITRQNQIAEPTYR----NWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVE 479
            +T Q Q A   Y+    +W +GL DCC+D   C C TF P C  C +   + E  CTP + P     LRT  R R  I+GSI  D     +C  CA+CQ+ R++   E
Sbjct:    5 VTSQPQSASTCYQTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCTP-YLPGGLHSLRTGMRERYRIQGSIGKDWAALTFCLPCALCQMARELKIRE 111
[Close]
BLAST of Placenta-specific gene 8 protein vs. UniProt/SwissProt
Match: sp|Q6PCW6|CNFN_MOUSE (Cornifelin OS=Mus musculus OX=10090 GN=Cnfn PE=1 SV=1)

HSP 1 Score: 68.9366 bits (167), Expect = 4.738e-14
Identity = 40/108 (37.04%), Postives = 55/108 (50.93%), Query Frame = 3 
Query:  168 ITRQNQIAEPTYR----NWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVE 479
            +T Q Q A   Y+    +W +GL DCC+D   C C TF P C  C +   + E  C P + P     LRT  R R HI+GS+  D     +C  CA+CQ+ R++   E
Sbjct:    5 VTSQPQCANTCYQTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCAP-YLPGGLHSLRTGMRERYHIQGSVGHDWAALTFCLPCALCQMARELKIRE 111
[Close]
BLAST of Placenta-specific gene 8 protein vs. UniProt/SwissProt
Match: sp|Q3ZCB2|PLAC8_BOVIN (Placenta-specific gene 8 protein OS=Bos taurus OX=9913 GN=PLAC8 PE=3 SV=1)

HSP 1 Score: 67.0106 bits (162), Expect = 2.385e-13
Identity = 42/114 (36.84%), Postives = 59/114 (51.75%), Query Frame = 3 
Query:  132 VFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYE-FVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 470
            V VTQPG G+           P   NW +GL DC  DC  C C TFC  C  C +     E  +C       +++ +RT +R+R  I GSI  D  +T+ C  C++CQ+KRD++
Sbjct:    9 VIVTQPGVGSGP--------APQNSNWQTGLCDCFSDCGVCLCGTFCFTCLACQVASDMNECCLC------GTSVAMRTLYRTRYGIPGSICDDFMVTHCCPLCSLCQIKRDIN 108
[Close]
BLAST of Placenta-specific gene 8 protein vs. UniProt/SwissProt
Match: sp|A1L4L8|PL8L1_HUMAN (PLAC8-like protein 1 OS=Homo sapiens OX=9606 GN=PLAC8L1 PE=2 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 2.995e-13
Identity = 40/115 (34.78%), Postives = 58/115 (50.43%), Query Frame = 3 
Query:  126 TTVFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 470
             +  V QP +G    T    I + T   WS+GLF  C D   C+C  FCP C  C +   Y E +C PL  P ST  LR   R R+ I+G++  D    + C+  ++CQ+ R++ 
Sbjct:   45 ASAVVKQPVRGASGRTTITAIVQ-TGGGWSTGLFSVCRDRRICFCGLFCPMCLECDIARHYGECLCWPLL-PGSTFALRIGTRERHKIQGTLCEDWLAVHCCWAFSICQVARELK 157
[Close]
BLAST of Placenta-specific gene 8 protein vs. UniProt/SwissProt
Match: sp|Q08EJ0|PL8L1_MOUSE (PLAC8-like protein 1 OS=Mus musculus OX=10090 GN=Plac8l1 PE=2 SV=2)

HSP 1 Score: 67.781 bits (164), Expect = 4.530e-13
Identity = 40/113 (35.40%), Postives = 59/113 (52.21%), Query Frame = 3 
Query:  132 VFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 470
            V V QP +G    T    I + T  +WS+GLF  C D   C+    CP C  C +   Y E +C PL  P ST  LR   R R+ I+G++  DC + + C+  ++CQ+ R++ 
Sbjct:   47 VVVKQPIRGAIGRTTVAAIVQ-TGGDWSTGLFSVCRDRKICFWGLLCPMCLECDIARHYGECLCWPLL-PGSTFALRIGTRERHRIQGTLCEDCVVVHCCWPFSICQVARELK 157
[Close]
BLAST of Placenta-specific gene 8 protein vs. TrEMBL
Match: A0A4E0RMG0 (Placenta-specific gene 8 protein OS=Fasciola hepatica OX=6192 GN=D915_001276 PE=4 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 1.411e-25
Identity = 53/121 (43.80%), Postives = 71/121 (58.68%), Query Frame = 3 
Query:  138 VTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 500
            +  P   +  I+  +Q  +  +R+W  GL  C  D  SC CVT C  CY+CYM+  Y E VCTPLF P   ++LRT HR R  I GS+  DC  + +C +C++CQL RDM Y E   GYL+
Sbjct:    3 IAYPDGSHAPIS--DQPHQIPFRDWHDGLCQCSSDWKSCACVTLCTCCYMCYMFKRYNENVCTPLFIPTPIMMLRTYHRGRERIVGSLFRDCVTSAFCPWCSLCQLDRDMKYQEITRGYLD 121
[Close]
BLAST of Placenta-specific gene 8 protein vs. TrEMBL
Match: A0A4S2L0X4 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_010192 PE=4 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 3.725e-25
Identity = 52/106 (49.06%), Postives = 65/106 (61.32%), Query Frame = 3 
Query:  183 QIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 500
            Q  +  +R+W  GLF C +D  SC  VTFC  CY+CYMY  Y E +   L TPAS ++LRT HR R  I GS+  DC  +  C +C +CQL RDM YVE   GYL+
Sbjct:   16 QPKQIPFRDWHDGLFGCRNDWKSCLYVTFCTPCYICYMYERYGECLLGSLVTPASVMMLRTFHRGRERIYGSLFKDCLHSTLCPWCVLCQLDRDMKYVEATKGYLD 121
[Close]
BLAST of Placenta-specific gene 8 protein vs. TrEMBL
Match: A0A504YJJ1 (Placenta-specific protein OS=Fasciola gigantica OX=46835 GN=FGIG_01274 PE=4 SV=1)

HSP 1 Score: 103.605 bits (257), Expect = 8.186e-25
Identity = 51/121 (42.15%), Postives = 71/121 (58.68%), Query Frame = 3 
Query:  138 VTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 500
            +  P   +  I+  +Q  +  +R+W  GL  C  D  SC CVT C  CY+CYM++ Y E +CTPL  P   ++LRT HR R  I GS+  DC  + +C +C++CQL RDM Y E   GYL+
Sbjct:    3 IAYPDGSHAPIS--DQPHQIPFRDWHDGLCQCSSDWKSCACVTLCTWCYMCYMFNRYNENLCTPLLIPTPIMMLRTYHRGRERIVGSLFRDCVTSAFCPWCSLCQLDRDMKYQEITRGYLD 121
[Close]
BLAST of Placenta-specific gene 8 protein vs. TrEMBL
Match: A0A1S8WWB7 (Putative Cys-rich domain protein (Fragment) OS=Opisthorchis viverrini OX=6198 GN=X801_05422 PE=4 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 3.968e-24
Identity = 56/124 (45.16%), Postives = 72/124 (58.06%), Query Frame = 3 
Query:  183 QIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE*IINSILFLSK-T*FYPC 551
            Q  +  +R+W  GL+ C +D  SC  VTFC  CY+C+MY  Y E +   L TPAS ++LRT HR R  I GS+  DC  +  C +C +CQL RDM YVE   GYL+    S   LS  + FYP 
Sbjct:   12 QPKQVPFRDWHDGLYGCRNDWKSCLYVTFCTPCYICHMYERYGECLFGSLITPASIMMLRTFHRGRERIYGSLFKDCLQSILCPWCVLCQLDRDMKYVEATKGYLDVKCRSEKLLSAYSHFYPA 135
[Close]
BLAST of Placenta-specific gene 8 protein vs. TrEMBL
Match: A0A5J4NRE5 (Uncharacterized protein OS=Paragonimus westermani OX=34504 GN=DEA37_0010981 PE=4 SV=1)

HSP 1 Score: 102.449 bits (254), Expect = 4.857e-24
Identity = 53/129 (41.09%), Postives = 69/129 (53.49%), Query Frame = 3 
Query:  114 NSPMTTVFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 500
            ++P  T  ++QP Q N  + +        YR+W  GL  C ++C +C    F   C  C+MY  Y E  CTP   P S ++L  KHRSR+ I GSI  DCC    C  CA+C+L RDM YVE  NG L 
Sbjct:   24 SAPTATPLLSQPNQINVIVNQPEPTRGTGYRDWHDGLCSCGNNCGNCLLTAFFYPCVECHMYQRYGECCCTPCVIPMSGMVLAVKHRSRHRIVGSISGDCCTFMCCAPCALCRLYRDMVYVEGVNGTLS 152
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Cavefish
Match: ponzr2 (cornifelin homolog [Source:NCBI gene;Acc:103025611])

HSP 1 Score: 70.0922 bits (170), Expect = 7.391e-15
Identity = 43/133 (32.33%), Postives = 61/133 (45.86%), Query Frame = 3 
Query:  108 CFNSPMTTVFVTQPGQGNQAITRQNQIAEPTY-------RNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLF-----TPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 470
            CF  P  T   +     + A+T +  I  P+          W SG+ DCCDD   C    +C  C+ C     Y + +C PL       PA+TL +R   R R  IKG++  DC +   C  CA CQ+ R+M+
Sbjct:   21 CFTVPYQTKSASGASANHSAMTTKVVITPPSMVLESRVSDEWGSGICDCCDDVPECCFAFWCCPCFACIKTKEYGQCLCLPLLDICGIVPAATLSMRVSMRHRYGIKGTLCNDCLIATCCTSCAWCQMSREMN 153
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Cavefish
Match: ponzr6 (cornifelin homolog [Source:NCBI gene;Acc:103028345])

HSP 1 Score: 68.1662 bits (165), Expect = 1.366e-14
Identity = 37/96 (38.54%), Postives = 51/96 (53.12%), Query Frame = 3 
Query:  207 NWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPL-------FTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDY 473
             WSSG+ DCC+D   C    +CP C +C     Y E +C PL         P  T  +R+  R R HI+GS+  DCC++  C  CA CQ+ R++ Y
Sbjct:   23 QWSSGICDCCEDMGICCFGFWCPYCLMCNTTKKYGECMCLPLVELCFGGLIPPVTYSMRSSMRERYHIQGSMCDDCCVSTCCGICAWCQIARELKY 118
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Cavefish
Match: ponzr6 (cornifelin homolog [Source:NCBI gene;Acc:103028345])

HSP 1 Score: 68.1662 bits (165), Expect = 1.569e-14
Identity = 37/96 (38.54%), Postives = 51/96 (53.12%), Query Frame = 3 
Query:  207 NWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPL-------FTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDY 473
             WSSG+ DCC+D   C    +CP C +C     Y E +C PL         P  T  +R+  R R HI+GS+  DCC++  C  CA CQ+ R++ Y
Sbjct:   23 QWSSGICDCCEDMGICCFGFWCPYCLMCNTTKKYGECMCLPLVELCFGGLIPPVTYSMRSSMRERYHIQGSMCDDCCVSTCCGICAWCQIARELKY 118
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Cavefish
Match: ponzr6 (cornifelin homolog [Source:NCBI gene;Acc:103028345])

HSP 1 Score: 68.5514 bits (166), Expect = 1.808e-14
Identity = 40/115 (34.78%), Postives = 59/115 (51.30%), Query Frame = 3 
Query:  207 NWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPL-------FTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE*IINSILFLS 530
             WSSG+ DCC+D   C    +CP C +C     Y E +C PL         P  T  +R+  R R HI+GS+  DCC++  C  CA CQ+ R++ Y   +      I+NS + ++
Sbjct:   23 QWSSGICDCCEDMGICCFGFWCPYCLMCNTTKKYGECMCLPLVELCFGGLIPPVTYSMRSSMRERYHIQGSMCDDCCVSTCCGICAWCQIARELKYRRQQPQV---IVNSSVNVA 134
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Cavefish
Match: ponzr6 (cornifelin homolog [Source:NCBI gene;Acc:103028345])

HSP 1 Score: 68.5514 bits (166), Expect = 1.808e-14
Identity = 40/115 (34.78%), Postives = 59/115 (51.30%), Query Frame = 3 
Query:  207 NWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPL-------FTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE*IINSILFLS 530
             WSSG+ DCC+D   C    +CP C +C     Y E +C PL         P  T  +R+  R R HI+GS+  DCC++  C  CA CQ+ R++ Y   +      I+NS + ++
Sbjct:   23 QWSSGICDCCEDMGICCFGFWCPYCLMCNTTKKYGECMCLPLVELCFGGLIPPVTYSMRSSMRERYHIQGSMCDDCCVSTCCGICAWCQIARELKYRRQQPQV---IVNSSVNVA 134
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009354.1 (pep scaffold:Pmarinus_7.0:GL483774:7229:14014:-1 gene:ENSPMAG00000008464.1 transcript:ENSPMAT00000009354.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.8474 bits (146), Expect = 1.472e-12
Identity = 36/119 (30.25%), Postives = 55/119 (46.22%), Query Frame = 3 
Query:  132 VFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKN 488
            V VTQP      +  Q Q        WSS + DC  D   C C  FC     C +   + E  C P+  P + + LRT  R R+HI+G++  D    + C  C  CQ+ R++ + +++ 
Sbjct:    5 VLVTQPVAHTVNVQGQAQ--------WSSHMMDCFQDTEICVCGFFCLPLLQCKVASDFGECFCVPML-PGALMALRTGIRERHHIEGTVFDDFVSLWCCNHCTTCQMARELRHQKNRG 114
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001184.1 (pep scaffold:Pmarinus_7.0:GL488356:6425:7851:-1 gene:ENSPMAG00000001063.1 transcript:ENSPMAT00000001184.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.225 bits (134), Expect = 2.717e-11
Identity = 29/73 (39.73%), Postives = 41/73 (56.16%), Query Frame = 3 
Query:  255 WCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDY 473
             C  FC  C  C M   + E  C P+  P S++ LRT  R R HI+GSI  DC +  +C+ CA CQ+ R++ +
Sbjct:   12 LCGIFCMLCLNCRMAKDFGECFCLPIL-PGSSMALRTAIRERYHIQGSICDDCVMLTFCFCCATCQMAREIKH 83
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Nematostella
Match: EDO42647 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0V8])

HSP 1 Score: 56.6102 bits (135), Expect = 1.039e-10
Identity = 32/96 (33.33%), Postives = 47/96 (48.96%), Query Frame = 3 
Query:  204 RNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFV-----CTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYV 476
            R+WSSGLF+C  D   C     CP   LC +     E +     C  +    +   LR K R+  +I+GS+  D      C  CA+CQ+ R++D+V
Sbjct:   28 RDWSSGLFECTKDIGGCLVTFLCPCVTLCQISQRMGEGLAYGCCCADI----AAFTLRAKLRTEQNIQGSLCNDAIHVSCCMHCALCQMSRELDHV 119
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Nematostella
Match: EDO42612 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0W1])

HSP 1 Score: 50.8322 bits (120), Expect = 1.812e-8
Identity = 32/91 (35.16%), Postives = 45/91 (49.45%), Query Frame = 3 
Query:  204 RNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYV 476
            R+W SG+  C DD  SC    FCP   L  +     E  C P   P + + LR K R   +I+GS+I D C       C +CQL R++ ++
Sbjct:   52 RDWHSGMCGCFDDIGSCLLGYFCPCFLLIDVSQRMGEGCCFPCCCPGALVGLRVKLRVEQNIQGSLINDYCAVQCLPLCVLCQLSRELKHL 142
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Nematostella
Match: EDO50068 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFB0])

HSP 1 Score: 47.7506 bits (112), Expect = 1.343e-7
Identity = 30/99 (30.30%), Postives = 44/99 (44.44%), Query Frame = 3 
Query:  204 RNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCT-------PLFTPASTLLL----RTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDM 467
             +W++GLF C +DC +C      P    CY +    E V           F P   L++    R K R ++ I GS I DC  T  C FC++ Q  + +
Sbjct:    3 NDWNNGLFGCFNDCGTCLITYIAP----CYTFGKNAEAVGDSCLLCGLAFFVPVVDLIVMSSVRGKIREQHGISGSFIGDCAATICCPFCSLVQSAQQV 97
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Nematostella
Match: EDO44794 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUR8])

HSP 1 Score: 43.1282 bits (100), Expect = 6.578e-6
Identity = 28/99 (28.28%), Postives = 46/99 (46.46%), Query Frame = 3 
Query:  207 NWSSGLFDCCDDCASCWCVTFCPECYL-----------CYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 470
            +WSSG+  C +D  +C    FCP C +           C+++       C  +F  A    +R K R ++ I+GS   DC + ++C  CA  Q  R++ 
Sbjct:    2 SWSSGICGCFEDINTCALTYFCP-CVVAGKNAEAVGENCFLHGFLSTLGCVGIFCGAK---IREKIREKHGIEGSFGNDCIMHWFCPLCAYSQEARELK 96
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Medaka
Match: plac8l1 (PLAC8 like 1 [Source:NCBI gene;Acc:101175585])

HSP 1 Score: 63.5438 bits (153), Expect = 1.748e-12
Identity = 42/112 (37.50%), Postives = 54/112 (48.21%), Query Frame = 3 
Query:  132 VFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDM 467
            V +TQPG G    T        T  NWS+GLF+   D  +C      P C    + H Y E +C PL  P ST  +R   R R  I+GS+  D    Y CY  A+CQ+ R+M
Sbjct:   47 VVLTQPGLG--VTTTTITTITQTGGNWSTGLFNIWGDKTTCLLGALVPCCLDLSLAHQYGECLCLPLL-PGSTFAIRVGIRERYKIQGSVCEDWTAVYCCYPLAVCQMIREM 155
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Medaka
Match: ponzr1 (cornifelin homolog B [Source:NCBI gene;Acc:110017082])

HSP 1 Score: 61.6178 bits (148), Expect = 6.720e-12
Identity = 38/115 (33.04%), Postives = 55/115 (47.83%), Query Frame = 3 
Query:  159 NQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFT--PASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYL 497
            + A+TR +  A  T   WS+G+ +CC D  +C C  +C  C  C     +      PL       T LLR+  R R+HI GS I DCC   +CY C  CQ+ R++    +    +
Sbjct:   26 SAALTRSSMTAVGT---WSTGMCECCADVGTCCCAMWCFPCMQCQTAQKHGWCCAMPLLDICGVVTCLLRSSIRERHHIPGSCIDDCCKCMFCYPCVWCQMHREVKVRSNAGSAV 137
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Medaka
Match: ENSORLT00000028572.1 (cornifelin homolog [Source:NCBI gene;Acc:101172524])

HSP 1 Score: 57.7658 bits (138), Expect = 7.754e-11
Identity = 37/123 (30.08%), Postives = 51/123 (41.46%), Query Frame = 3 
Query:  132 VFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 500
            V   QPG G      Q          WS+GL  C +DC  C    FCP    CY  H Y E  C     P     +RT  R    I+G++  D  + + C  C MC++ R+   +  +NG + 
Sbjct:    5 VVTHQPGAGGYGTNVQTG-------EWSTGLCSCFNDCLICALGFFCPAGLSCYTAHKYGENFCLGC-VPGGMTAMRTHMRLTYGIQGTVCNDAIMVFCCGLCEMCRMARE---IRIRNGEVS 116
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Medaka
Match: ponzr3 (cornifelin homolog A [Source:NCBI gene;Acc:101160195])

HSP 1 Score: 57.3806 bits (137), Expect = 1.496e-10
Identity = 39/120 (32.50%), Postives = 54/120 (45.00%), Query Frame = 3 
Query:  126 TTVFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLF-----TPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 470
             TV  TQP         +  I   T   WSSG+ DC DD  SC    +C  C+ C       E +C PL       P  T  +R   R +  I+G+I  DC  +++C  C+ CQ+ R+M 
Sbjct:    3 VTVKTTQP---------RPYITTSTSNEWSSGICDCFDDLRSCCFAFWCFPCFACITSKKAGECLCLPLLDGFGCIPPITTAMRVSIRKQYGIEGTICRDCVFSFFCGPCSWCQISREMK 113
[Close]
BLAST of Placenta-specific gene 8 protein vs. Ensembl Medaka
Match: ENSORLT00000012432.2 (cornifelin-like [Source:NCBI gene;Acc:101164880])

HSP 1 Score: 57.7658 bits (138), Expect = 2.504e-10
Identity = 33/111 (29.73%), Postives = 53/111 (47.75%), Query Frame = 3 
Query:  186 IAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPL---------------FTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDY 473
            + E    +W++ LFDC +D ++C    +C  C  C +   + E  C P+               F P   + +R   RSR  IKGSI AD   +Y+C  C+ CQ+ R++ +
Sbjct:    1 MGERRLTDWNTDLFDCFEDASTCCYGCWCGPCLACTVSGRFGERYCLPMLDISTTGSQILPIPAFVPPVAVSMRAAMRSRYGIKGSIAADIAASYYCAPCSWCQMHRELKH 111
[Close]
BLAST of Placenta-specific gene 8 protein vs. Planmine SMEST
Match: SMESG000050245.1 (SMESG000050245.1)

HSP 1 Score: 266.159 bits (679), Expect = 2.552e-92
Identity = 126/126 (100.00%), Postives = 126/126 (100.00%), Query Frame = 3 
Query:  123 MTTVFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 500
            MTTVFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE
Sbjct:    1 MTTVFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 126
[Close]
BLAST of Placenta-specific gene 8 protein vs. Planmine SMEST
Match: SMESG000050244.1 (SMESG000050244.1)

HSP 1 Score: 239.195 bits (609), Expect = 1.168e-81
Identity = 112/126 (88.89%), Postives = 115/126 (91.27%), Query Frame = 3 
Query:  123 MTTVFVTQPGQGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 500
            MTTV +TQPG  NQ ITRQ+QI   TYRNWSSGLFDCCDDC SC  + FCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE
Sbjct:    1 MTTVIITQPGHKNQVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 126
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BLAST of Placenta-specific gene 8 protein vs. Planmine SMEST
Match: SMESG000050244.1 (SMESG000050244.1)

HSP 1 Score: 233.802 bits (595), Expect = 1.356e-79
Identity = 112/129 (86.82%), Postives = 115/129 (89.15%), Query Frame = 3 
Query:  123 MTTVFVTQPGQGNQA---ITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 500
            MTTV +TQPG  NQ    ITRQ+QI   TYRNWSSGLFDCCDDC SC  + FCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE
Sbjct:    1 MTTVIITQPGHKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 129
[Close]
BLAST of Placenta-specific gene 8 protein vs. Planmine SMEST
Match: SMESG000050175.1 (SMESG000050175.1)

HSP 1 Score: 145.206 bits (365), Expect = 1.761e-44
Identity = 75/131 (57.25%), Postives = 90/131 (68.70%), Query Frame = 3 
Query:  120 PMTTVFVTQPGQ---GNQAITRQNQIAEPTY-RNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 500
            P  TV + QPG    GNQ +  Q Q  +    R+WSS LF CC+DC SCW      ECYLCY+Y  + EFVCTPLFTP+S LLLRTKHR+R+ IKG+I+ D C  Y CY C MCQLKRDM+YVE+ NG L+
Sbjct:    9 PCNTVII-QPGVPTYGNQTVIIQQQPNQRNLPRDWSSELFGCCEDCTSCWLSLCFAECYLCYLYSKHNEFVCTPLFTPSSLLLLRTKHRARHRIKGTIMGDACKIYCCYICTMCQLKRDMNYVEETNGSLD 138
[Close]
BLAST of Placenta-specific gene 8 protein vs. Planmine SMEST
Match: SMESG000050177.1 (SMESG000050177.1)

HSP 1 Score: 132.494 bits (332), Expect = 1.865e-39
Identity = 68/132 (51.52%), Postives = 83/132 (62.88%), Query Frame = 3 
Query:  123 MTTVFVTQPG------QGNQAITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 500
            + T  + QPG        NQ      Q      R WSSG+  CC+DC SC    F   CY CY++HIY EF+CTP+    S L LRTKHR+R+ I+G+II DCC TYWCY+CA+CQLKRDMDYVED  G L+
Sbjct:    9 LPTPVLVQPGVMANPMNINQTTVIIQQPVANGPRLWSSGICGCCEDCTSCCLTMFFTHCYTCYLFHIYDEFLCTPICMYDSVLQLRTKHRARHGIRGTIIEDCCKTYWCYWCAICQLKRDMDYVEDTKGSLD 140
The following BLAST results are available for this feature:
BLAST of Placenta-specific gene 8 protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PLAC8L16.238e-1434.78PLAC8 like 1 [Source:HGNC Symbol;Acc:HGNC:31746][more]
CNFN1.491e-1334.86cornifelin [Source:HGNC Symbol;Acc:HGNC:30183][more]
CNFN1.491e-1334.86cornifelin [Source:HGNC Symbol;Acc:HGNC:30183][more]
PLAC88.060e-1235.65placenta associated 8 [Source:HGNC Symbol;Acc:HGNC... [more]
PLAC88.060e-1235.65placenta associated 8 [Source:HGNC Symbol;Acc:HGNC... [more]
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BLAST of Placenta-specific gene 8 protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Placenta-specific gene 8 protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Placenta-specific gene 8 protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ponzr55.025e-1537.40plac8 onzin related protein 5 [Source:ZFIN;Acc:ZDB... [more]
ponzr55.343e-1537.40plac8 onzin related protein 5 [Source:ZFIN;Acc:ZDB... [more]
plac8l11.898e-1437.84PLAC8 like 1 [Source:ZFIN;Acc:ZDB-GENE-091204-165][more]
plac8l12.605e-1437.27PLAC8 like 1 [Source:ZFIN;Acc:ZDB-GENE-091204-165][more]
ponzr61.167e-1234.51plac8 onzin related protein 6 [Source:ZFIN;Acc:ZDB... [more]
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BLAST of Placenta-specific gene 8 protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
myo193.196e-1436.70myosin XIX [Source:Xenbase;Acc:XB-GENE-999897][more]
ifi358.153e-1434.68interferon induced protein 35 [Source:Xenbase;Acc:... [more]
ENSXETT00000008293.19.889e-1433.33novel protein similar to cornifelin [Source:NCBI g... [more]
ifi351.505e-1338.89interferon induced protein 35 [Source:Xenbase;Acc:... [more]
abtb11.735e-1136.21ankyrin repeat and BTB (POZ) domain containing 1 [... [more]
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BLAST of Placenta-specific gene 8 protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cnfn6.773e-1537.04cornifelin [Source:MGI Symbol;Acc:MGI:1919633][more]
Cnfn8.821e-1537.04cornifelin [Source:MGI Symbol;Acc:MGI:1919633][more]
Plac8l16.477e-1435.40PLAC8-like 1 [Source:MGI Symbol;Acc:MGI:1916651][more]
Plac81.024e-1335.77placenta-specific 8 [Source:MGI Symbol;Acc:MGI:244... [more]
Plac81.024e-1335.77placenta-specific 8 [Source:MGI Symbol;Acc:MGI:244... [more]
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BLAST of Placenta-specific gene 8 protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q0VBW2|CNFN_BOVIN4.003e-1437.96Cornifelin OS=Bos taurus OX=9913 GN=CNFN PE=3 SV=1[more]
sp|Q6PCW6|CNFN_MOUSE4.738e-1437.04Cornifelin OS=Mus musculus OX=10090 GN=Cnfn PE=1 S... [more]
sp|Q3ZCB2|PLAC8_BOVIN2.385e-1336.84Placenta-specific gene 8 protein OS=Bos taurus OX=... [more]
sp|A1L4L8|PL8L1_HUMAN2.995e-1334.78PLAC8-like protein 1 OS=Homo sapiens OX=9606 GN=PL... [more]
sp|Q08EJ0|PL8L1_MOUSE4.530e-1335.40PLAC8-like protein 1 OS=Mus musculus OX=10090 GN=P... [more]
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BLAST of Placenta-specific gene 8 protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4E0RMG01.411e-2543.80Placenta-specific gene 8 protein OS=Fasciola hepat... [more]
A0A4S2L0X43.725e-2549.06Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A504YJJ18.186e-2542.15Placenta-specific protein OS=Fasciola gigantica OX... [more]
A0A1S8WWB73.968e-2445.16Putative Cys-rich domain protein (Fragment) OS=Opi... [more]
A0A5J4NRE54.857e-2441.09Uncharacterized protein OS=Paragonimus westermani ... [more]
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BLAST of Placenta-specific gene 8 protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ponzr27.391e-1532.33cornifelin homolog [Source:NCBI gene;Acc:103025611... [more]
ponzr61.366e-1438.54cornifelin homolog [Source:NCBI gene;Acc:103028345... [more]
ponzr61.569e-1438.54cornifelin homolog [Source:NCBI gene;Acc:103028345... [more]
ponzr61.808e-1434.78cornifelin homolog [Source:NCBI gene;Acc:103028345... [more]
ponzr61.808e-1434.78cornifelin homolog [Source:NCBI gene;Acc:103028345... [more]
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BLAST of Placenta-specific gene 8 protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000009354.11.472e-1230.25pep scaffold:Pmarinus_7.0:GL483774:7229:14014:-1 g... [more]
ENSPMAT00000001184.12.717e-1139.73pep scaffold:Pmarinus_7.0:GL488356:6425:7851:-1 ge... [more]
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BLAST of Placenta-specific gene 8 protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Placenta-specific gene 8 protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO426471.039e-1033.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO426121.812e-835.16Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO500681.343e-730.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO447946.578e-628.28Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Placenta-specific gene 8 protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
plac8l11.748e-1237.50PLAC8 like 1 [Source:NCBI gene;Acc:101175585][more]
ponzr16.720e-1233.04cornifelin homolog B [Source:NCBI gene;Acc:1100170... [more]
ENSORLT00000028572.17.754e-1130.08cornifelin homolog [Source:NCBI gene;Acc:101172524... [more]
ponzr31.496e-1032.50cornifelin homolog A [Source:NCBI gene;Acc:1011601... [more]
ENSORLT00000012432.22.504e-1029.73cornifelin-like [Source:NCBI gene;Acc:101164880][more]
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BLAST of Placenta-specific gene 8 protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000050245.12.552e-92100.00SMESG000050245.1[more]
SMESG000050244.11.168e-8188.89SMESG000050244.1[more]
SMESG000050244.11.356e-7986.82SMESG000050244.1[more]
SMESG000050175.11.761e-4457.25SMESG000050175.1[more]
SMESG000050177.11.865e-3951.52SMESG000050177.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010206 ID=SMED30010206|Name=Placenta-specific gene 8 protein|organism=Schmidtea mediterranea sexual|type=transcript|length=618bp
GTGAAATAAAATTTTATTAATATTCATCGAAACAATAAATTTATGTGAAA
ATGACTCAATAAAAAAGTACTTGAACACCTAATATAAAATGAAATATAAG
ATACGGTTGTTTTAATTCACCGATGACCACAGTTTTCGTAACGCAGCCAG
GTCAAGGAAACCAAGCCATCACTAGGCAGAACCAAATAGCGGAGCCTACT
TATAGGAATTGGAGTTCAGGATTATTTGACTGTTGTGATGACTGCGCGTC
TTGTTGGTGTGTCACTTTTTGTCCAGAATGTTATCTCTGTTACATGTACC
ATATCTACTATGAATTCGTTTGCACTCCCTTATTTACTCCAGCTTCAACA
TTACTTTTAAGGACAAAACATAGAAGCAGAAACCATATTAAAGGAAGTAT
CATAGCTGATTGCTGTCTAACTTATTGGTGTTACTTTTGCGCAATGTGCC
AACTGAAACGCGACATGGACTATGTGGAGGATAAAAACGGATACCTCGAA
TAAATCATCAATTCAATTTTATTTTTATCTAAAACATAATTTTATCCATG
TTCTTAGACATTTGAGTGTTCTAAGAATATATTTAATGTTTTTTATTGAA
TAAATAAATTAATATTTG
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000421tail
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR006461PLAC_motif_containing
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006461PLAC8 motif-containing proteinTIGRFAMTIGR01571TIGR01571coord: 28..115
e-value: 5.1E-15
score: 54.1
IPR006461PLAC8 motif-containing proteinPFAMPF04749PLAC8coord: 30..113
e-value: 2.2E-12
score: 47.8
IPR006461PLAC8 motif-containing proteinPANTHERPTHR15907FAMILY NOT NAMEDcoord: 7..119
NoneNo IPR availablePANTHERPTHR15907:SF93PLACENTA-SPECIFIC 8, TANDEM DUPLICATE 1-RELATEDcoord: 7..119