ribonucleoside diphosphate reductase subunit M2-2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Expression Details ribonucleoside diphosphate reductase subunit M2-2 ( RRM2-2 ) is expressed during Stage 2, Stage 3, Stage 4, Stage 5, Stage 6, Stage 7 and Stage 8 in the neoblast and blastomere
Click to see image symbols and abbreviations
Cell cycle activity is restricted to piwi-1 blastomeres, and all blastomeres are cycling. SPIM reconstructed S4 embryo costained with piwi-1 (red) and RNR M2-2 (green). RNR M2-2 expression is restricted to piwi-1+ blastomeres, and all piwi-1+ cells co-express RNR M2-2. Several fluorescent beads used for 3-dimensional reconstruction are visible (red). Anatomical Expression
PAGE et. al., 2020SMED30010115 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 46Note: Hover over icons to view figure legend
Homology
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Human
Match: RRM2B (ribonucleotide reductase regulatory TP53 inducible subunit M2B [Source:HGNC Symbol;Acc:HGNC:17296]) HSP 1 Score: 424.091 bits (1089), Expect = 3.621e-148 Identity = 214/305 (70.16%), Postives = 251/305 (82.30%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL + R IQY DIW+M+ +A++SFWT EV+LSKD HW K+ DE+YFI+H+LAFFAASDGIVNENLVERF QEV++PEA FY FQI IEN+HSEMYSLLID+Y+ D + + LFNAIETMP V+KKA WALRWI+D+KSTFG RVVAFAAVEG+FFSGSFA+IFWLKKRGLMPGL FSNELISRDEGLHCDFACLMF+YL +KPS E+V ++I +AV IE+EFLT+ALPV LIGMN M +YIEFVADRLLVELG K + ENP DFM+NI ++GKTNFFEKRV EY +V
Sbjct: 32 EPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAV 336
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Human
Match: RRM2 (ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452]) HSP 1 Score: 423.705 bits (1088), Expect = 2.114e-147 Identity = 216/305 (70.82%), Postives = 249/305 (81.64%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+ R I+Y DIW+M+ KA +SFWT EV+LSKD HW+ + +ERYFI+HVLAFFAASDGIVNENLVERF QEV+I EA FY FQIA+ENIHSEMYSLLID+Y+ D + + LFNAIETMPCV+KKA WALRWI DK++T+G RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L KPS E+V ++I AV IE+EFLT+ALPV LIGMN M +YIEFVADRL++ELG K + ENP DFM+NI ++GKTNFFEKRVGEY V
Sbjct: 70 EPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGV 374
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Human
Match: RRM2 (ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452]) HSP 1 Score: 423.705 bits (1088), Expect = 2.114e-147 Identity = 216/305 (70.82%), Postives = 249/305 (81.64%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+ R I+Y DIW+M+ KA +SFWT EV+LSKD HW+ + +ERYFI+HVLAFFAASDGIVNENLVERF QEV+I EA FY FQIA+ENIHSEMYSLLID+Y+ D + + LFNAIETMPCV+KKA WALRWI DK++T+G RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L KPS E+V ++I AV IE+EFLT+ALPV LIGMN M +YIEFVADRL++ELG K + ENP DFM+NI ++GKTNFFEKRVGEY V
Sbjct: 70 EPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGV 374
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Human
Match: RRM2B (ribonucleotide reductase regulatory TP53 inducible subunit M2B [Source:HGNC Symbol;Acc:HGNC:17296]) HSP 1 Score: 422.165 bits (1084), Expect = 1.806e-146 Identity = 214/305 (70.16%), Postives = 251/305 (82.30%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL + R IQY DIW+M+ +A++SFWT EV+LSKD HW K+ DE+YFI+H+LAFFAASDGIVNENLVERF QEV++PEA FY FQI IEN+HSEMYSLLID+Y+ D + + LFNAIETMP V+KKA WALRWI+D+KSTFG RVVAFAAVEG+FFSGSFA+IFWLKKRGLMPGL FSNELISRDEGLHCDFACLMF+YL +KPS E+V ++I +AV IE+EFLT+ALPV LIGMN M +YIEFVADRLLVELG K + ENP DFM+NI ++GKTNFFEKRV EY +V
Sbjct: 89 EPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAV 393
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Human
Match: RRM2 (ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452]) HSP 1 Score: 423.32 bits (1087), Expect = 2.392e-146 Identity = 216/305 (70.82%), Postives = 249/305 (81.64%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+ R I+Y DIW+M+ KA +SFWT EV+LSKD HW+ + +ERYFI+HVLAFFAASDGIVNENLVERF QEV+I EA FY FQIA+ENIHSEMYSLLID+Y+ D + + LFNAIETMPCV+KKA WALRWI DK++T+G RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L KPS E+V ++I AV IE+EFLT+ALPV LIGMN M +YIEFVADRL++ELG K + ENP DFM+NI ++GKTNFFEKRVGEY V
Sbjct: 130 EPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGV 434
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Celegans
Match: rnr-2 (Ribonucleoside-diphosphate reductase small chain [Source:UniProtKB/Swiss-Prot;Acc:P42170]) HSP 1 Score: 383.645 bits (984), Expect = 3.682e-132 Identity = 198/315 (62.86%), Postives = 243/315 (77.14%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV---EDKHKFD 1031
E +L + +R +++ DIW + KA +SFWTV EV+L KD W+KMN DE+YFI+ +LAFFAASDGIVNENL ERF EV++ EA FY FQIAIENIHSEMYS LI++Y+ D +N LFNA++ ++KKA WALRWISDKK++F R++AFAAVEGIFFSGSFASIFWLKKRGLMPGL SNELISRDEGLH DFACL++ L K + +++ D+IK+AV IE+EFLT+ALPV +IGMN M +YIEFVAD LLVELGCDK + ++NP DFM+NI IDGKTNFFEKRV EY V E + +FD
Sbjct: 62 EPMLQDLDNRFVIFPLKHHDIWNFYKKAVASFWTVEEVDLGKDMNDWEKMNGDEQYFISRILAFFAASDGIVNENLCERFSNEVQVSEARFFYGFQIAIENIHSEMYSKLIETYIRDETERNTLFNAVDEFEFIKKKADWALRWISDKKASFAERLIAFAAVEGIFFSGSFASIFWLKKRGLMPGLTHSNELISRDEGLHRDFACLLYSKLQKKLTQQRIYDIIKDAVAIEQEFLTEALPVDMIGMNCRLMSQYIEFVADHLLVELGCDKLYKSKNPFDFMENISIDGKTNFFEKRVSEYQRPGVMVNEAERQFD 376
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Celegans
Match: F19G12.2 (pep chromosome:WBcel235:X:1427774:1430871:1 gene:WBGene00017610.1 transcript:F19G12.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F19G12.2) HSP 1 Score: 211.075 bits (536), Expect = 3.648e-62 Identity = 117/206 (56.80%), Postives = 151/206 (73.30%), Query Frame = 3
Query: 384 IAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLH--CDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEY 995
IA+ENIHSEMY+ L+++Y+ D +N LFNAI T ++ KA W LRWISD + F R+ AFAAVEGIFFS SFA+IFWLKKRGL+PGL SNELIS LH C F+ + KP+ ++ ++I E+V +E++F+ ++LP +LIGMN MC+Y+EFVAD LL ELG K +NT+NP DFM+NI I+GKTNFFEKRV EY
Sbjct: 445 IAVENIHSEMYAKLLEAYIRDDAERNILFNAITTFKFIKAKADWCLRWISDHNAPFSERLAAFAAVEGIFFSSSFAAIFWLKKRGLLPGLTHSNELISMFL-LHPNCFFSTFNLQR-RRKPAESRITEIINESVLVEQDFVRESLPTNLIGMNQHMMCKYVEFVADLLLEELGYSKRYNTKNPFDFMENISIEGKTNFFEKRVSEY 648
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Fly
Match: RnrS (gene:FBgn0011704 transcript:FBtr0088046) HSP 1 Score: 419.853 bits (1078), Expect = 3.657e-146 Identity = 208/306 (67.97%), Postives = 250/306 (81.70%), Query Frame = 3
Query: 93 MEILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
+E LL E+ R IQY DIW+M+ KA +SFWTV EV+LSKD W ++ DDER+FI+HVLAFFAASDGIVNENLVERF QEV+I EA FY FQIA+EN+HSEMYS+LID+Y+ D + LFNAIETMP V++KA WAL WIS K + FG R++AFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRDEGLHCDFA LMF++L +P E+++++I++AV IE+EFLTDALPV+LIGMN + M +YIEFVADRLLVELG K +NT+NP +FM+ I +DGKTNFFEK+VGEY V
Sbjct: 73 LEPLLRENPRRFVIFPIQYHDIWQMYKKAEASFWTVEEVDLSKDLTDWHRLKDDERHFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENVHSEMYSVLIDTYIRDPHQREYLFNAIETMPAVKRKADWALSWISSKSANFGERIIAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFAVLMFQHLVQRPKRERIIEIIRDAVAIEQEFLTDALPVNLIGMNCDLMSQYIEFVADRLLVELGVGKIYNTKNPFNFMEMISLDGKTNFFEKKVGEYQRMGV 378
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Zebrafish
Match: rrm2 (ribonucleotide reductase M2 polypeptide [Source:NCBI gene;Acc:30733]) HSP 1 Score: 426.787 bits (1096), Expect = 2.353e-149 Identity = 218/305 (71.48%), Postives = 248/305 (81.31%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+ R IQY DIW+M+ KA +SFWT EV+LSKD HW + D+ERYFI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D++ + LFNAIETMPCV+KKA WAL WI DK + +G RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L +KPS E V +I AV IE+EFLTDALPV LIGMN + M +YIEFVADRLL+ELG DK + ENP DFM+NI ++GKTNFFEKRVGEY V
Sbjct: 38 EPLLKENPHRFVIFPIQYHDIWQMYKKAEASFWTAEEVDLSKDLQHWDSLKDEERYFISHVLAFFAASDGIVNENLVERFTQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDSKEREFLFNAIETMPCVKKKADWALNWIGDKNARYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLINKPSEETVKKIIMNAVEIEQEFLTDALPVKLIGMNCDLMKQYIEFVADRLLLELGFDKVYRVENPFDFMENISLEGKTNFFEKRVGEYQRMGV 342
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Zebrafish
Match: rrm2 (ribonucleotide reductase regulatory subunit M2 [Source:NCBI gene;Acc:100330864]) HSP 1 Score: 426.787 bits (1096), Expect = 2.353e-149 Identity = 218/305 (71.48%), Postives = 248/305 (81.31%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+ R IQY DIW+M+ KA +SFWT EV+LSKD HW + D+ERYFI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D++ + LFNAIETMPCV+KKA WAL WI DK + +G RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L +KPS E V +I AV IE+EFLTDALPV LIGMN + M +YIEFVADRLL+ELG DK + ENP DFM+NI ++GKTNFFEKRVGEY V
Sbjct: 38 EPLLKENPHRFVIFPIQYHDIWQMYKKAEASFWTAEEVDLSKDLQHWDSLKDEERYFISHVLAFFAASDGIVNENLVERFTQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDSKEREFLFNAIETMPCVKKKADWALNWIGDKNARYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLINKPSEETVKKIIMNAVEIEQEFLTDALPVKLIGMNCDLMKQYIEFVADRLLLELGFDKVYRVENPFDFMENISLEGKTNFFEKRVGEYQRMGV 342
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Zebrafish
Match: rrm2 (ribonucleotide reductase M2 polypeptide [Source:NCBI gene;Acc:30733]) HSP 1 Score: 426.017 bits (1094), Expect = 2.386e-149 Identity = 218/305 (71.48%), Postives = 248/305 (81.31%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+ R IQY DIW+M+ KA +SFWT EV+LSKD HW + D+ERYFI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D++ + LFNAIETMPCV+KKA WAL WI DK + +G RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L +KPS E V +I AV IE+EFLTDALPV LIGMN + M +YIEFVADRLL+ELG DK + ENP DFM+NI ++GKTNFFEKRVGEY V
Sbjct: 15 EPLLKENPHRFVIFPIQYHDIWQMYKKAEASFWTAEEVDLSKDLQHWDSLKDEERYFISHVLAFFAASDGIVNENLVERFTQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDSKEREFLFNAIETMPCVKKKADWALNWIGDKNARYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLINKPSEETVKKIIMNAVEIEQEFLTDALPVKLIGMNCDLMKQYIEFVADRLLLELGFDKVYRVENPFDFMENISLEGKTNFFEKRVGEYQRMGV 319
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Zebrafish
Match: rrm2 (ribonucleotide reductase regulatory subunit M2 [Source:NCBI gene;Acc:100330864]) HSP 1 Score: 426.017 bits (1094), Expect = 2.386e-149 Identity = 218/305 (71.48%), Postives = 248/305 (81.31%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+ R IQY DIW+M+ KA +SFWT EV+LSKD HW + D+ERYFI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D++ + LFNAIETMPCV+KKA WAL WI DK + +G RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L +KPS E V +I AV IE+EFLTDALPV LIGMN + M +YIEFVADRLL+ELG DK + ENP DFM+NI ++GKTNFFEKRVGEY V
Sbjct: 15 EPLLKENPHRFVIFPIQYHDIWQMYKKAEASFWTAEEVDLSKDLQHWDSLKDEERYFISHVLAFFAASDGIVNENLVERFTQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDSKEREFLFNAIETMPCVKKKADWALNWIGDKNARYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLINKPSEETVKKIIMNAVEIEQEFLTDALPVKLIGMNCDLMKQYIEFVADRLLLELGFDKVYRVENPFDFMENISLEGKTNFFEKRVGEYQRMGV 319
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Zebrafish
Match: rrm2 (ribonucleotide reductase M2 polypeptide [Source:NCBI gene;Acc:30733]) HSP 1 Score: 427.557 bits (1098), Expect = 3.129e-149 Identity = 218/305 (71.48%), Postives = 248/305 (81.31%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+ R IQY DIW+M+ KA +SFWT EV+LSKD HW + D+ERYFI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D++ + LFNAIETMPCV+KKA WAL WI DK + +G RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L +KPS E V +I AV IE+EFLTDALPV LIGMN + M +YIEFVADRLL+ELG DK + ENP DFM+NI ++GKTNFFEKRVGEY V
Sbjct: 67 EPLLKENPHRFVIFPIQYHDIWQMYKKAEASFWTAEEVDLSKDLQHWDSLKDEERYFISHVLAFFAASDGIVNENLVERFTQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDSKEREFLFNAIETMPCVKKKADWALNWIGDKNARYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLINKPSEETVKKIIMNAVEIEQEFLTDALPVKLIGMNCDLMKQYIEFVADRLLLELGFDKVYRVENPFDFMENISLEGKTNFFEKRVGEYQRMGV 371
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Xenopus
Match: col6a6 (collagen, type VI, alpha 6 [Source:Xenbase;Acc:XB-GENE-6051153]) HSP 1 Score: 424.476 bits (1090), Expect = 6.335e-148 Identity = 215/310 (69.35%), Postives = 254/310 (81.94%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHK 1025
E LL ++ R IQY DIW+M+ KA +SFWT EV+LSKD HW+ + +E+YFI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D + + LFNAIET+PCV+KKA WALRWI DK++T+G RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L +KPS E+V+ LI +AV IE+EFLT+ALPV+LIGMN M +YIEFVADRLL+ELG +K + NP DFM+NI ++GKTNFFEK+VGEY V K K
Sbjct: 61 EPLLKDNPHRFVIFPIQYHDIWQMYKKAEASFWTAEEVDLSKDLRHWESLKAEEKYFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETLPCVKKKADWALRWIGDKQATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVNKPSEERVVQLITDAVQIEQEFLTEALPVNLIGMNCTLMKQYIEFVADRLLLELGFNKVFKATNPFDFMENISLEGKTNFFEKKVGEYQKMGVMSKPK 370
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Xenopus
Match: col6a6 (collagen, type VI, alpha 6 [Source:Xenbase;Acc:XB-GENE-6051153]) HSP 1 Score: 422.165 bits (1084), Expect = 7.558e-148 Identity = 215/310 (69.35%), Postives = 254/310 (81.94%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHK 1025
E LL ++ R IQY DIW+M+ KA +SFWT EV+LSKD HW+ + +E+YFI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D + + LFNAIET+PCV+KKA WALRWI DK++T+G RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L +KPS E+V+ LI +AV IE+EFLT+ALPV+LIGMN M +YIEFVADRLL+ELG +K + NP DFM+NI ++GKTNFFEK+VGEY V K K
Sbjct: 5 EPLLKDNPHRFVIFPIQYHDIWQMYKKAEASFWTAEEVDLSKDLRHWESLKAEEKYFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETLPCVKKKADWALRWIGDKQATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVNKPSEERVVQLITDAVQIEQEFLTEALPVNLIGMNCTLMKQYIEFVADRLLLELGFNKVFKATNPFDFMENISLEGKTNFFEKKVGEYQKMGVMSKPK 314
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Xenopus
Match: col6a6 (collagen, type VI, alpha 6 [Source:Xenbase;Acc:XB-GENE-6051153]) HSP 1 Score: 422.165 bits (1084), Expect = 1.032e-147 Identity = 215/310 (69.35%), Postives = 254/310 (81.94%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHK 1025
E LL ++ R IQY DIW+M+ KA +SFWT EV+LSKD HW+ + +E+YFI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D + + LFNAIET+PCV+KKA WALRWI DK++T+G RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L +KPS E+V+ LI +AV IE+EFLT+ALPV+LIGMN M +YIEFVADRLL+ELG +K + NP DFM+NI ++GKTNFFEK+VGEY V K K
Sbjct: 12 EPLLKDNPHRFVIFPIQYHDIWQMYKKAEASFWTAEEVDLSKDLRHWESLKAEEKYFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETLPCVKKKADWALRWIGDKQATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVNKPSEERVVQLITDAVQIEQEFLTEALPVNLIGMNCTLMKQYIEFVADRLLLELGFNKVFKATNPFDFMENISLEGKTNFFEKKVGEYQKMGVMSKPK 321
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Xenopus
Match: rrm2b (ribonucleotide reductase M2 B (TP53 inducible) [Source:NCBI gene;Acc:100144925]) HSP 1 Score: 421.779 bits (1083), Expect = 1.788e-147 Identity = 215/311 (69.13%), Postives = 250/311 (80.39%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYS----MSSVED 1016
E L ++ R I Y DIW+M+ KA++SFWT EV+LSKD HW+K+ +ER FI+H+LAFFAASDGIVNENLVERF QEV++PEA FY FQI IEN+HSEMYSLLI++Y+ D + LFNAIETMPCV+KKAQWALRWISD+K++FG RVVAFAAVEGIFFSGSFA+IFWLKKRGLMPGL FSNELISRDEGLH DFACLMF YL KP+ E+V ++I AV IE+EFLT+ALPVSLIGMN M YIEFVADRLLVELGC K + ENP DFM+NI ++GKTNFFEKRV EY M+ ED
Sbjct: 18 EPFLRKNPQRFVIFPIHYPDIWKMYKKAQASFWTAEEVDLSKDLVHWEKLKPEERNFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIETYIKDPRRREFLFNAIETMPCVRKKAQWALRWISDRKASFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHTDFACLMFHYLVKKPTEERVTEIIVNAVRIEQEFLTEALPVSLIGMNCTLMKTYIEFVADRLLVELGCSKAFKAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAHTED 328
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Xenopus
Match: col6a6 (collagen, type VI, alpha 6 [Source:Xenbase;Acc:XB-GENE-6051153]) HSP 1 Score: 422.55 bits (1085), Expect = 1.789e-147 Identity = 215/310 (69.35%), Postives = 254/310 (81.94%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHK 1025
E LL ++ R IQY DIW+M+ KA +SFWT EV+LSKD HW+ + +E+YFI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D + + LFNAIET+PCV+KKA WALRWI DK++T+G RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L +KPS E+V+ LI +AV IE+EFLT+ALPV+LIGMN M +YIEFVADRLL+ELG +K + NP DFM+NI ++GKTNFFEK+VGEY V K K
Sbjct: 33 EPLLKDNPHRFVIFPIQYHDIWQMYKKAEASFWTAEEVDLSKDLRHWESLKAEEKYFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETLPCVKKKADWALRWIGDKQATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVNKPSEERVVQLITDAVQIEQEFLTEALPVNLIGMNCTLMKQYIEFVADRLLLELGFNKVFKATNPFDFMENISLEGKTNFFEKKVGEYQKMGVMSKPK 342
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Mouse
Match: Rrm2 (ribonucleotide reductase M2 [Source:MGI Symbol;Acc:MGI:98181]) HSP 1 Score: 423.32 bits (1087), Expect = 1.952e-147 Identity = 213/305 (69.84%), Postives = 250/305 (81.97%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+ R I+Y DIW+M+ KA +SFWT EV+LSKD HW+ + DER+FI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D + + LFNAIETMPCV+KKA WALRWI DK++T+G RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L KP+ ++V ++I AV IE+EFLT+ALPV LIGMN M +YIEFVADRL++ELG +K + ENP DFM+NI ++GKTNFFEKRVGEY V
Sbjct: 71 EPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGV 375
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Mouse
Match: Rrm2b (ribonucleotide reductase M2 B (TP53 inducible) [Source:MGI Symbol;Acc:MGI:2155865]) HSP 1 Score: 421.394 bits (1082), Expect = 3.775e-147 Identity = 213/305 (69.84%), Postives = 249/305 (81.64%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL + R IQY DIW M+ +A++SFWT EV+LSKD HW K+ DE+YFI+H+LAFFAASDGIVNENLVERF QEV++PEA FY FQI IEN+HSEMYSLLID+Y+ D + + LFNAIETMP V+KKA WALRWI+D+KSTFG RVVAFAAVEGIFFSGSFA+IFWLKKRGLMPGL FSNELISRDEGLHCDFACLMF+YL +KPS ++V ++I +AV IE+EFLT+ALPV LIGMN M +YIEFVADRLL ELG K + ENP DFM+NI ++GKTNFFEKRV EY +V
Sbjct: 32 EPLLRKSSRRFVIFPIQYPDIWRMYKQAQASFWTAEEVDLSKDLPHWNKLKSDEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEDRVREIIADAVQIEQEFLTEALPVGLIGMNCVLMKQYIEFVADRLLGELGFSKIFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAV 336
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Mouse
Match: Rrm2b (ribonucleotide reductase M2 B (TP53 inducible) [Source:MGI Symbol;Acc:MGI:2155865]) HSP 1 Score: 387.497 bits (994), Expect = 1.299e-134 Identity = 197/270 (72.96%), Postives = 228/270 (84.44%), Query Frame = 3
Query: 201 NEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
EV+LSKD HW K+ DE+YFI+H+LAFFAASDGIVNENLVERF QEV++PEA FY FQI IEN+HSEMYSLLID+Y+ D + + LFNAIETMP V+KKA WALRWI+D+KSTFG RVVAFAAVEGIFFSGSFA+IFWLKKRGLMPGL FSNELISRDEGLHCDFACLMF+YL +KPS ++V ++I +AV IE+EFLT+ALPV LIGMN M +YIEFVADRLL ELG K + ENP DFM+NI ++GKTNFFEKRV EY +V
Sbjct: 15 GEVDLSKDLPHWNKLKSDEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEDRVREIIADAVQIEQEFLTEALPVGLIGMNCVLMKQYIEFVADRLLGELGFSKIFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAV 284
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Mouse
Match: Rrm2 (ribonucleotide reductase M2 [Source:MGI Symbol;Acc:MGI:98181]) HSP 1 Score: 290.812 bits (743), Expect = 1.659e-97 Identity = 164/286 (57.34%), Postives = 190/286 (66.43%), Query Frame = 3
Query: 153 DIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
DIW+M+ KA +SFWT EV+LSKD HW+ + DER+FI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D + + LFNAIETMPCV+KKA WALRWI DK++T+G RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRD EF+ D L + L G +K + ENP DFM+NI ++GKTNFFEKRVGEY V
Sbjct: 2 DIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRD------------------------------------EFVADRLMLEL-----------------------GFNKIFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGV 228
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Mouse
Match: Rrm2 (ribonucleotide reductase M2 [Source:MGI Symbol;Acc:MGI:98181]) HSP 1 Score: 254.218 bits (648), Expect = 2.029e-83 Identity = 133/186 (71.51%), Postives = 154/186 (82.80%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGL 653
E LL E+ R I+Y DIW+M+ KA +SFWT EV+LSKD HW+ + DER+FI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D + + LFNAIETMPCV+KKA WALRWI DK++T+G RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL
Sbjct: 40 EPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL 225
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. UniProt/SwissProt
Match: sp|P79733|RIR2_DANRE (Ribonucleoside-diphosphate reductase subunit M2 OS=Danio rerio OX=7955 GN=rrm2 PE=1 SV=1) HSP 1 Score: 427.557 bits (1098), Expect = 2.362e-148 Identity = 218/305 (71.48%), Postives = 248/305 (81.31%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+ R IQY DIW+M+ KA +SFWT EV+LSKD HW + D+ERYFI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D++ + LFNAIETMPCV+KKA WAL WI DK + +G RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L +KPS E V +I AV IE+EFLTDALPV LIGMN + M +YIEFVADRLL+ELG DK + ENP DFM+NI ++GKTNFFEKRVGEY V
Sbjct: 67 EPLLKENPHRFVIFPIQYHDIWQMYKKAEASFWTAEEVDLSKDLQHWDSLKDEERYFISHVLAFFAASDGIVNENLVERFTQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDSKEREFLFNAIETMPCVKKKADWALNWIGDKNARYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLINKPSEETVKKIIMNAVEIEQEFLTDALPVKLIGMNCDLMKQYIEFVADRLLLELGFDKVYRVENPFDFMENISLEGKTNFFEKRVGEYQRMGV 371
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. UniProt/SwissProt
Match: sp|Q7LG56|RIR2B_HUMAN (Ribonucleoside-diphosphate reductase subunit M2 B OS=Homo sapiens OX=9606 GN=RRM2B PE=1 SV=1) HSP 1 Score: 424.091 bits (1089), Expect = 1.739e-147 Identity = 214/305 (70.16%), Postives = 251/305 (82.30%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL + R IQY DIW+M+ +A++SFWT EV+LSKD HW K+ DE+YFI+H+LAFFAASDGIVNENLVERF QEV++PEA FY FQI IEN+HSEMYSLLID+Y+ D + + LFNAIETMP V+KKA WALRWI+D+KSTFG RVVAFAAVEG+FFSGSFA+IFWLKKRGLMPGL FSNELISRDEGLHCDFACLMF+YL +KPS E+V ++I +AV IE+EFLT+ALPV LIGMN M +YIEFVADRLLVELG K + ENP DFM+NI ++GKTNFFEKRV EY +V
Sbjct: 32 EPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAV 336
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. UniProt/SwissProt
Match: sp|Q5R9G0|RIR2B_PONAB (Ribonucleoside-diphosphate reductase subunit M2 B OS=Pongo abelii OX=9601 GN=RRM2B PE=2 SV=1) HSP 1 Score: 423.705 bits (1088), Expect = 2.577e-147 Identity = 214/305 (70.16%), Postives = 251/305 (82.30%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL + R IQY DIW+M+ +A++SFWT EV+LSKD HW K+ DE+YFI+H+LAFFAASDGIVNENLVERF QEV++PEA FY FQI IEN+HSEMYSLLID+Y+ D + + LFNAIETMP V+KKA WALRWI+D+KSTFG RVVAFAAVEG+FFSGSFA+IFWLKKRGLMPGL FSNELISRDEGLHCDFACLMF+YL +KPS E+V ++I +AV IE+EFLT+ALPV LIGMN M +YIEFVADRLLVELG K + ENP DFM+NI ++GKTNFFEKRV EY +V
Sbjct: 32 EPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAV 336
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. UniProt/SwissProt
Match: sp|Q4R741|RIR2B_MACFA (Ribonucleoside-diphosphate reductase subunit M2 B OS=Macaca fascicularis OX=9541 GN=RRM2B PE=2 SV=1) HSP 1 Score: 423.705 bits (1088), Expect = 2.812e-147 Identity = 215/305 (70.49%), Postives = 251/305 (82.30%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL + R IQY DIW+M+ +A++SFWT EV+LSKD HW K+ DE+YFI+H+LAFFAASDGIVNENLVERF QEV++PEA FY FQI IEN+HSEMYSLLID+Y+ D + + LFNAIETMP V+KKA WALRWI+D+KSTFG RVVAFAAVEGIFFSGSFA+IFWLKKRGLMPGL FSNELISRDEGLHCDFACLMF+YL +KPS E+V ++I +AV IE+EFLT+ALPV LIGMN M +YIEFVADRLLVELG K + ENP DFM+NI ++GKTNFFEKRV EY +V
Sbjct: 32 EPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVQIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKIFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAV 336
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. UniProt/SwissProt
Match: sp|Q60561|RIR2_MESAU (Ribonucleoside-diphosphate reductase subunit M2 OS=Mesocricetus auratus OX=10036 GN=RRM2 PE=2 SV=1) HSP 1 Score: 424.091 bits (1089), Expect = 6.114e-147 Identity = 214/305 (70.16%), Postives = 251/305 (82.30%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+ R I+Y DIW+M+ KA +SFWT EV+LSKD HW+ + DER+FI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D++ + LFNAIETMPCV+KKA WALRWI DK++T+G RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L KPS ++V ++I AV IE+EFLT+ALPV LIGMN M +YIEFVADRL++ELG +K + ENP DFM+NI ++GKTNFFEKRVGEY V
Sbjct: 71 EPLLRENPRRFVVFPIEYHDIWKMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDSKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEQRVQEIITNAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFKVENPFDFMENISLEGKTNFFEKRVGEYQRMGV 375
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. TrEMBL
Match: I1ZI90 (Ribonucleoside diphosphate reductase subunit M2-2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 621.698 bits (1602), Expect = 0.000e+0 Identity = 316/316 (100.00%), Postives = 316/316 (100.00%), Query Frame = 3
Query: 93 MEILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHKFDDVN 1040
MEILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHKFDDVN
Sbjct: 1 MEILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHKFDDVN 316
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. TrEMBL
Match: A0A1W4XEU3 (ribonucleoside-diphosphate reductase subunit M2 B OS=Agrilus planipennis OX=224129 GN=LOC108743458 PE=4 SV=1) HSP 1 Score: 435.261 bits (1118), Expect = 4.716e-149 Identity = 222/306 (72.55%), Postives = 252/306 (82.35%), Query Frame = 3
Query: 93 MEILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
+E LL E+ R IQY DIWE + +A +SFWT EV+LSKD AHW K+++DER+FI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIAIENIHSEMYS LID+Y+ D E K LFNAIETMPCV+KKA WAL WIS K +TF RVVAFAAVEGIFFSGSFA+IFWLKKRGLMPGL FSNELISRDEGLHCDFACLMF Y+ KPS E+V D+I++AV IE+EFLTDALPVSLIGMN + M +YIEFVADRLLVELGCDK +N +NP DFM+ I DGKTNFFEK+VGEY V
Sbjct: 56 VEPLLRENPRRFVIFPIQYPDIWEKYKEAEASFWTTEEVDLSKDLAHWDKLSNDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAIENIHSEMYSTLIDTYIFDPEEKEFLFNAIETMPCVKKKADWALHWISSKNATFPERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFSYIVQKPSKERVTDIIRDAVKIEQEFLTDALPVSLIGMNCKLMSQYIEFVADRLLVELGCDKIYNVKNPFDFMNKISTDGKTNFFEKKVGEYQKIGV 361
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. TrEMBL
Match: W4Z9V7 (Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1) HSP 1 Score: 432.18 bits (1110), Expect = 2.820e-147 Identity = 221/319 (69.28%), Postives = 253/319 (79.31%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEY--------SMSSVEDKHKF 1028
E LL E+ R IQY DIW+ + KA +SFWT EV+LSKD HW + D+ER+FI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIAIENIHSEMYSLLID+Y+ D+ ++ LFNA+ET+PCV KKAQWAL WI + FGTR+VAFAAVEGIFFSGSFA+IFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L++KP E V +IKEAV IE+EFLTDALP SLIGMNA M YIEFVADRLLVELGC K W ENP DFM+NI ++GKTNFFEKRVGEY + SS + +H F
Sbjct: 88 EPLLRENARRFVIFPIQYHDIWQFYKKAEASFWTAEEVDLSKDLDHWANLKDEERHFISHVLAFFAASDGIVNENLVERFSQEVQVAEARCFYGFQIAIENIHSEMYSLLIDTYIKDSVQRDFLFNAVETLPCVTKKAQWALNWIGSDSADFGTRIVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLNNKPDEEHVQGIIKEAVAIEQEFLTDALPCSLIGMNAVLMKRYIEFVADRLLVELGCGKIWKVENPFDFMENISLEGKTNFFEKRVGEYQKMGVMSSTNSSTKKQHTF 406
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. TrEMBL
Match: A0A267H4E0 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig018616g1 PE=4 SV=1) HSP 1 Score: 429.869 bits (1104), Expect = 8.495e-147 Identity = 213/306 (69.61%), Postives = 254/306 (83.01%), Query Frame = 3
Query: 93 MEILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
+E LL E+ R + IQY DIW+M+ KA +SFWTV EV+LSKD WK++ D+ER+F+++VLAFFAASDGIVNENLVERF QEV+IPEA FY FQI IENIHSEMYSLLIDSYV D ++ LFNAIET+P V++KA WAL WIS K++TFG RVVAFAAVEGIFFSGSFA++FWLKKRGLMPGL FSNELISRDEGLH DFACLMF++L PS +++ ++I++AV IE+ FLT+ALPVSLIGMN SMC YIEFVADRLL EL C K +N+ENP DFM+NI ++GKTNFFEKRVGEY + V
Sbjct: 56 LEPLLKENPHRFVIMPIQYHDIWQMYKKAVASFWTVEEVDLSKDLEDWKQLTDNERHFVSYVLAFFAASDGIVNENLVERFAQEVQIPEARCFYGFQIMIENIHSEMYSLLIDSYVRDPAQRDLLFNAIETLPPVRQKADWALNWISHKRATFGERVVAFAAVEGIFFSGSFAAVFWLKKRGLMPGLTFSNELISRDEGLHTDFACLMFRHLQRPPSSQRIEEIIRDAVRIEQSFLTEALPVSLIGMNCASMCRYIEFVADRLLTELNCPKAFNSENPFDFMENISLEGKTNFFEKRVGEYQKAGV 361
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. TrEMBL
Match: A0A267GMY6 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006704g2 PE=4 SV=1) HSP 1 Score: 429.098 bits (1102), Expect = 1.485e-146 Identity = 213/305 (69.84%), Postives = 253/305 (82.95%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+ R + IQY DIW+M+ KA +SFWTV EV+LSKD WK++ D+ER+F+++VLAFFAASDGIVNENLVERF QEV+IPEA FY FQI IENIHSEMYSLLIDSYV D ++ LFNAIET+P V++KA WAL WIS K++TFG RVVAFAAVEGIFFSGSFA++FWLKKRGLMPGL FSNELISRDEGLH DFACLMF++L PS +++ ++I++AV IE+ FLT+ALPVSLIGMN SMC YIEFVADRLL EL C K +N+ENP DFM+NI ++GKTNFFEKRVGEY + V
Sbjct: 58 EPLLKENPHRFVIMPIQYHDIWQMYKKAVASFWTVEEVDLSKDLEDWKQLTDNERHFVSYVLAFFAASDGIVNENLVERFAQEVQIPEARCFYGFQIMIENIHSEMYSLLIDSYVRDPAQRDLLFNAIETLPPVRQKADWALNWISHKRATFGERVVAFAAVEGIFFSGSFAAVFWLKKRGLMPGLTFSNELISRDEGLHTDFACLMFRHLQRPPSSQRIEEIIRDAVRIEQSFLTEALPVSLIGMNCASMCRYIEFVADRLLTELNCPKAFNSENPFDFMENISLEGKTNFFEKRVGEYQKAGV 362
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Cavefish
Match: rrm2 (ribonucleotide reductase regulatory subunit M2 [Source:NCBI gene;Acc:103024314]) HSP 1 Score: 419.853 bits (1078), Expect = 3.940e-146 Identity = 210/305 (68.85%), Postives = 247/305 (80.98%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+ R IQY DIW+M+ KA +SFWT EV+LSKD HW+ + D+ERYFI+HVLAFFAASDGIVNENLVERF+QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D++ + LFNA+ET+PCV+KKA WAL WI +K + +G RVVAFAAVEGIFFSGSFA+IFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L +KPS V +I AV IE+EFLT ALPV LIGMN + M +YIEFVADRL++ELG K + ENP DFM+NI ++GKTNFFEKRVGEY V
Sbjct: 67 EPLLKENPRRFVIFPIQYHDIWQMYKKAEASFWTAEEVDLSKDLQHWESLKDEERYFISHVLAFFAASDGIVNENLVERFMQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDSKEREYLFNAVETLPCVKKKADWALNWIGNKNAKYGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLMNKPSESTVKKIIMNAVQIEQEFLTQALPVKLIGMNCDLMKQYIEFVADRLMLELGFSKIYKVENPFDFMENISLEGKTNFFEKRVGEYQRMGV 371
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Cavefish
Match: rrm2 (ribonucleotide reductase regulatory subunit M2 [Source:NCBI gene;Acc:103024314]) HSP 1 Score: 419.853 bits (1078), Expect = 3.940e-146 Identity = 210/305 (68.85%), Postives = 247/305 (80.98%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+ R IQY DIW+M+ KA +SFWT EV+LSKD HW+ + D+ERYFI+HVLAFFAASDGIVNENLVERF+QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D++ + LFNA+ET+PCV+KKA WAL WI +K + +G RVVAFAAVEGIFFSGSFA+IFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L +KPS V +I AV IE+EFLT ALPV LIGMN + M +YIEFVADRL++ELG K + ENP DFM+NI ++GKTNFFEKRVGEY V
Sbjct: 67 EPLLKENPRRFVIFPIQYHDIWQMYKKAEASFWTAEEVDLSKDLQHWESLKDEERYFISHVLAFFAASDGIVNENLVERFMQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDSKEREYLFNAVETLPCVKKKADWALNWIGNKNAKYGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLMNKPSESTVKKIIMNAVQIEQEFLTQALPVKLIGMNCDLMKQYIEFVADRLMLELGFSKIYKVENPFDFMENISLEGKTNFFEKRVGEYQRMGV 371
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Cavefish
Match: rrm2b (ribonucleoside-diphosphate reductase subunit M2 B-like [Source:NCBI gene;Acc:103028967]) HSP 1 Score: 411.764 bits (1057), Expect = 1.562e-143 Identity = 202/305 (66.23%), Postives = 251/305 (82.30%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+K R IQY DIW+M+ +A++SFWTV EV+LSKD HW+K+ ER+FI+HVLAFFAASDGIVNENLV+RF QEV++PEA +FY FQI IE++HSEMYS+LI++Y+ D + ++ LFNAIETMPCV++KA WAL+WISD+ STFG R++AFAAVEGIFFSGSFA+I+WLKKRGLMPGL +SNELISRDEGLHC+FACLM+ YL KPS ++V D+I +AV IE+EFLT+ALPV LIG+N M +YIEFVADRLL +L K + ENP DFM++I ++GKTNFFEKRV EY V
Sbjct: 30 EPLLRENKRRFVIFPIQYPDIWKMYKQAQASFWTVEEVDLSKDLVHWEKLKPGERHFISHVLAFFAASDGIVNENLVQRFSQEVQLPEARSFYGFQILIESVHSEMYSMLINTYIRDLKERDYLFNAIETMPCVKRKADWALQWISDRNSTFGERLIAFAAVEGIFFSGSFAAIYWLKKRGLMPGLTYSNELISRDEGLHCNFACLMYSYLVKKPSADRVRDIITKAVSIEQEFLTEALPVDLIGINCSLMKQYIEFVADRLLTDLAMPKVYKAENPFDFMESISLEGKTNFFEKRVAEYQRFGV 334
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Sea Lamprey
Match: rrm2 (ribonucleotide reductase regulatory subunit M2 [Source:NCBI gene;Acc:100330864]) HSP 1 Score: 412.535 bits (1059), Expect = 9.821e-145 Identity = 212/313 (67.73%), Postives = 251/313 (80.19%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDK--HKF 1028
E LL ++ R I+Y DIW+M+ KA +SFWT EV+LSKD HW+++ +E++FI+HVLAFFAASDGIVNENLVERF QEV+I EA FY FQIA+ENIHSEMYSLLID+Y+ D + LFNAIET+PCV+KKA WALRWISD +TFG RV+AFAAVEGIFFSGSFASIFWLKKRGLMPGL FSNELISRDEGLHCDFACLMF++L KP +V ++ +AV IE+EFLTDALPV+LIGMN + M +YIEFVADRLL ELGC K + ENP DFM+NI ++GKTNFFEK+V EY V K H+F
Sbjct: 19 EPLLRDNPRRFVIFPIEYPDIWQMYKKAEASFWTAEEVDLSKDQQHWERLKPEEQHFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPTQREFLFNAIETLPCVKKKADWALRWISDSNATFGERVLAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFRHLVHKPEEARVQQIVMDAVIIEQEFLTDALPVNLIGMNCDLMKQYIEFVADRLLGELGCAKVYRAENPFDFMENISLEGKTNFFEKKVAEYQKMGVMSKVDHQF 331
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Yeast
Match: RNR2 (Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits; RNR2 has a paralog, RNR4, that arose from the whole genome duplication [Source:SGD;Acc:S000003563]) HSP 1 Score: 376.326 bits (965), Expect = 1.013e-129 Identity = 190/309 (61.49%), Postives = 237/309 (76.70%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWK-KMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDK 1019
E LL EDK R I+Y +IW+ + +A +SFWT E++LSKD W +MN++ER+FI+ VLAFFAASDGIVNENLVE F EV+IPEA++FY FQI IENIHSE YSLLID+Y+ D + LFNAI T+P + +KA+WALRWI D + FG R+VAFA++EG+FFSGSFASIFWLKKRG+MPGL FSNELI RDEGLH DFACL+F +L +KP P V ++ EAV IE+ + DALPV+L+GMNA+ M +Y+EFVADRLLV G K++ ENP DFM+NI + GKTNFFEKRV +Y + V K
Sbjct: 76 EPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTNFFEKRVSDYQKAGVMSK 384
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Yeast
Match: RNR4 (Ribonucleotide-diphosphate reductase (RNR) small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits; relocalizes from nucleus to cytoplasm upon DNA replication stress; RNR4 has a paralog, RNR2, that arose from the whole genome duplication [Source:SGD;Acc:S000003412]) HSP 1 Score: 265.388 bits (677), Expect = 5.425e-87 Identity = 136/305 (44.59%), Postives = 207/305 (67.87%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKN-KLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSS 1007
EILL E+ R I+Y +IW + K +SFWT E+ L+KD ++K+ DD++ +I ++LA +SD +VN+ L+E F +++ PE ++FY FQI +ENI+SE+YS+++D++ D KN LF I +P V+ KA + RWIS+ S + R+VAFAA EGIF +G++AS+FWL + +MPGL +N I RD G + DF+CL+F +L +KP+P+ + +I EAV IEKE+ +++LPV GM+ +S+ YIEFVAD LL G +K++N NP +FM+++ GKT FFEK+V +Y +S
Sbjct: 25 EILLMENSRRFVMFPIKYHEIWAAYKKVEASFWTAEEIELAKDTEDFQKLTDDQKTYIGNLLALSISSDNLVNKYLIENFSAQLQNPEGKSFYGFQIMMENIYSEVYSMMVDAFFKDP--KNIPLFKEIANLPEVKHKAAFIERWISNDDSLYAERLVAFAAKEGIFQAGNYASMFWLTDKKIMPGLAMANRNICRDRGAYTDFSCLLFAHLRTKPNPKIIEKIITEAVEIEKEYYSNSLPVEKFGMDLKSIHTYIEFVADGLLQGFGNEKYYNAVNPFEFMEDVATAGKTTFFEKKVSDYQKAS 327
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Yeast
Match: YJL026C-A_mRNA (Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the verified gene YJL026W/RNR2 [Source:SGD;Acc:S000028660]) HSP 1 Score: 61.2326 bits (147), Expect = 1.032e-12 Identity = 34/66 (51.52%), Postives = 40/66 (60.61%), Query Frame = -2
Query: 551 SGDGLLLKYLNIKQAKSQ*SPSSRLINSLLKHNPGINPRFLSQNIDAKLPLKNIPSTAANATTLVP 748
+G GL K+ N K AKS PSS INSL K PGI P F +Q ++AK P K PS A AT+L P
Sbjct: 2 AGSGLFFKWANNKHAKSVCKPSSLQINSLEKVKPGIIPLFFNQKMEAKEPEKKTPSMEAKATSLSP 67
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Nematostella
Match: EDO42117 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2C2]) HSP 1 Score: 420.624 bits (1080), Expect = 1.289e-147 Identity = 219/314 (69.75%), Postives = 251/314 (79.94%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV---EDKHKF 1028
E LL E+ R L IQY +IW+M+ KA +SFWT EV+LSKD + K+NDDER F++HVLAFFAASDGIVNENLVE F QEV+IPEA FY FQIAIENIHSEMYSLLI+S + D K LFNAIETMPCV KKA WAL WI+ ++++FG R++AFAAVEGIFFSGSFA+IFWLKKRGLMPGL FSNELISRDEGLHCDFACLM+KYL +KP E V +IK+AV IE+EFLT ALPV LIGMN M +YIEFVADRLLV L C K +N ENP DFM+NI ++GKTNFFEKRVGEY S V +D HKF
Sbjct: 22 EPLLRENPHRFVILPIQYPEIWQMYKKAEASFWTAEEVDLSKDSHDFAKLNDDERMFVSHVLAFFAASDGIVNENLVECFSQEVQIPEARCFYGFQIAIENIHSEMYSLLIESLIKDKAEKVNLFNAIETMPCVMKKAHWALNWINPQRASFGERIIAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMYKYLVNKPDEETVRGIIKDAVVIEQEFLTSALPVKLIGMNCALMRQYIEFVADRLLVALNCQKVYNVENPFDFMENISLEGKTNFFEKRVGEYQKSGVMSEKDSHKF 335
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Nematostella
Match: EDO42087 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2C1]) HSP 1 Score: 420.239 bits (1079), Expect = 7.368e-147 Identity = 218/314 (69.43%), Postives = 251/314 (79.94%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV---EDKHKF 1028
E LL E+ R L IQY +IW+M+ KA +SFWT EV+LSKD + K+NDDER F++HVLAFFAASDGIVNENLVE F QEV+IPEA FY FQIAIENIHSEMYSLLI+S + D K LFNAIETMPCV KKA WAL WI+ ++++FG R++AFAAVEGIFFSGSFA+IFWLKKRGLMPGL FSNELISRDEGLHCDFACLM+KYL +KP E V +IK+AV IE+EFLT ALPV LIGMN M +YIEFVADRLLV L C K +N ENP DFM+NI ++GKTNF+EKRVGEY S V +D HKF
Sbjct: 65 EPLLRENPHRFVILPIQYPEIWQMYKKAEASFWTAEEVDLSKDSHDFAKLNDDERMFVSHVLAFFAASDGIVNENLVECFCQEVQIPEARCFYGFQIAIENIHSEMYSLLIESLIKDKAEKVNLFNAIETMPCVMKKAHWALNWINPQRASFGERIIAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMYKYLVNKPDEETVRGIIKDAVVIEQEFLTSALPVKLIGMNCALMRQYIEFVADRLLVALNCQKVYNVENPFDFMENISLEGKTNFYEKRVGEYQKSGVMSEKDSHKF 378
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Nematostella
Match: EDO42116 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2C0]) HSP 1 Score: 419.083 bits (1076), Expect = 2.195e-146 Identity = 218/314 (69.43%), Postives = 250/314 (79.62%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV---EDKHKF 1028
E LL E+ R L IQY +IW+M+ KA +SFWT EV+LSKD + K+ND ER F++HVLAFFAASDGIVNENLVE F QEV+IPEA FY FQIAIENIHSEMYSLLI+S + D K LFNAIETMPCV KKA WAL WI+ ++++FG R++AFAAVEGIFFSGSFA+IFWLKKRGLMPGL FSNELISRDEGLHCDFACLM+KYL +KP E V +IK+AV IE+EFLT ALPV LIGMN M +YIEFVADRLLV L C K +N ENP DFM+NI ++GKTNFFEKRVGEY S V +D HKF
Sbjct: 65 EPLLRENPHRFVILPIQYTEIWQMYKKAEASFWTAEEVDLSKDSHDFAKLNDHERMFVSHVLAFFAASDGIVNENLVECFCQEVQIPEARCFYGFQIAIENIHSEMYSLLIESLIKDKAEKVNLFNAIETMPCVMKKAHWALNWINPQRASFGERIIAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMYKYLVNKPDEETVRGIIKDAVVIEQEFLTSALPVKLIGMNCALMRQYIEFVADRLLVALNCQKVYNAENPFDFMENISLEGKTNFFEKRVGEYQKSGVMSDKDSHKF 378
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Nematostella
Match: EDO28315 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6T9]) HSP 1 Score: 244.588 bits (623), Expect = 3.863e-80 Identity = 129/222 (58.11%), Postives = 166/222 (74.77%), Query Frame = 3
Query: 90 IMEILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWK-KMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQ 752
++E +L E+K R I++ DIWE + K +SFWT E++L +D W K+N+DE+YFI H+LAFFAASDGIVNENL E F+ EV+ EA+ FY FQI +ENIHSE YSLLID+YV D K+KLF+AIE P +++KA+WAL+WI + +F R++AFAAVEGIFFSG+F SIFWLKKRGLMPGL FSNELISRDEG+HCDFA + + P++
Sbjct: 3 VVEPILQENKDRFVIFPIKHHDIWEWYKKMEASFWTAEEIDLHQDITDWNTKLNEDEKYFIKHILAFFAASDGIVNENLAENFVNEVQYAEAKFFYGFQIMMENIHSETYSLLIDTYVKDEVEKDKLFHAIEVFPAIKRKAEWALKWI--ESDSFAERLIAFAAVEGIFFSGAFCSIFWLKKRGLMPGLTFSNELISRDEGVHCDFAVHIHNHHLINKVPKE 222
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Medaka
Match: RRM2 (ribonucleoside-diphosphate reductase subunit M2-like [Source:NCBI gene;Acc:101166844]) HSP 1 Score: 425.246 bits (1092), Expect = 1.858e-148 Identity = 212/305 (69.51%), Postives = 249/305 (81.64%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+ R +QY DIW+M+ KA +SFWT EV+LSKD HW+ + DDER+FI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D + + LFNAIET+PCV++KA WAL WI +K + +G RVVAFAAVEGIFFSGSFA+IFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L +KPS E V ++I+ AV IE+EFLT+ALPV LIGMN E M +YIEFVADRLL+ELG K + ENP DFM+NI ++GKTNFFEKRVGEY V
Sbjct: 60 EPLLKENPRRFVIFPVQYHDIWQMYKKAEASFWTAEEVDLSKDLQHWETLKDDERFFISHVLAFFAASDGIVNENLVERFTQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETLPCVKRKADWALNWIGNKHAAYGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVNKPSSETVTEIIRNAVEIEQEFLTEALPVKLIGMNCELMKQYIEFVADRLLLELGFSKIYRAENPFDFMENISLEGKTNFFEKRVGEYQRMGV 364
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Medaka
Match: ENSORLT00000025443.2 (ribonucleoside-diphosphate reductase subunit M2 [Source:NCBI gene;Acc:101158912]) HSP 1 Score: 402.905 bits (1034), Expect = 6.273e-141 Identity = 202/282 (71.63%), Postives = 236/282 (83.69%), Query Frame = 3
Query: 165 MFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
M+ KA +SFWT EV+LSKD HW+ + DDER+FI+HVLAFFAASDGIVNENLVERF QEV++ EA FY FQIA+ENIHSEMYSLLID+Y+ D + + LFNAIET+PCV++KA WAL WI +K + +G RVVAFAAVEGIFFSGSFA+IFWLKKRGLMPGL FSNELISRDEGLHCDFACLMFK+L +KPS E V ++I+ AV IE+EFLT+ALPV LIGMN E M +YIEFVADRLL+ELG K + ENP DFM+NI ++GKTNFFEKRVGEY V
Sbjct: 1 MYKKAEASFWTAEEVDLSKDLQHWETLKDDERFFISHVLAFFAASDGIVNENLVERFTQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETLPCVKRKADWALNWIGNKHAAYGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVNKPSSETVTEIIRNAVEIEQEFLTEALPVKLIGMNCELMKQYIEFVADRLLLELGFSKIYRAENPFDFMENISLEGKTNFFEKRVGEYQRMGV 282
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Medaka
Match: rrm2b (ribonucleoside-diphosphate reductase subunit M2 B [Source:NCBI gene;Acc:101164326]) HSP 1 Score: 380.948 bits (977), Expect = 2.106e-131 Identity = 199/305 (65.25%), Postives = 248/305 (81.31%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+ R IQY DIW+M+ +A++SFWTV EV+LSKD HW ++ DE++FI++VLAFFAASDGIVNENLV+RF EV++PEA +FYSFQI IE +HSEMYSLLI++Y+ D + ++ LFNAI+TMPCV++KA WAL WI+D KSTFG R+VAFAAVEGIFFSGSFA+I+WLKKRGL+PGL +SNELISRDEGLHC+FACL++ YL KPS ++V +I +AV IE+EFLT+ALPV LIGMN M +YIEFVADRLL +L DK + ENP DFM++I ++GKTNFFEKRV EY V
Sbjct: 33 EPLLRENPRRFVIFPIQYPDIWKMYKQAQASFWTVEEVDLSKDLVHWDRLKPDEKHFISNVLAFFAASDGIVNENLVQRFSLEVQVPEARSFYSFQILIETVHSEMYSLLINTYIRDLKERDYLFNAIQTMPCVKRKADWALEWINDNKSTFGERLVAFAAVEGIFFSGSFAAIYWLKKRGLLPGLTYSNELISRDEGLHCNFACLLYSYLVKKPSEDRVRGIITKAVCIEQEFLTEALPVDLIGMNCCLMKQYIEFVADRLLADLDLDKVYKVENPFDFMESISLEGKTNFFEKRVAEYQRFGV 337
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Medaka
Match: rrm2b (ribonucleoside-diphosphate reductase subunit M2 B [Source:NCBI gene;Acc:101164326]) HSP 1 Score: 380.178 bits (975), Expect = 4.946e-131 Identity = 199/305 (65.25%), Postives = 248/305 (81.31%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
E LL E+ R IQY DIW+M+ +A++SFWTV EV+LSKD HW ++ DE++FI++VLAFFAASDGIVNENLV+RF EV++PEA +FYSFQI IE +HSEMYSLLI++Y+ D + ++ LFNAI+TMPCV++KA WAL WI+D KSTFG R+VAFAAVEGIFFSGSFA+I+WLKKRGL+PGL +SNELISRDEGLHC+FACL++ YL KPS ++V +I +AV IE+EFLT+ALPV LIGMN M +YIEFVADRLL +L DK + ENP DFM++I ++GKTNFFEKRV EY V
Sbjct: 35 EPLLRENPRRFVIFPIQYPDIWKMYKQAQASFWTVEEVDLSKDLVHWDRLKPDEKHFISNVLAFFAASDGIVNENLVQRFSLEVQVPEARSFYSFQILIETVHSEMYSLLINTYIRDLKERDYLFNAIQTMPCVKRKADWALEWINDNKSTFGERLVAFAAVEGIFFSGSFAAIYWLKKRGLLPGLTYSNELISRDEGLHCNFACLLYSYLVKKPSEDRVRGIITKAVCIEQEFLTEALPVDLIGMNCCLMKQYIEFVADRLLADLDLDKVYKVENPFDFMESISLEGKTNFFEKRVAEYQRFGV 339
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Medaka
Match: ENSORLT00000040809.1 (ribonucleoside-diphosphate reductase subunit M2 [Source:NCBI gene;Acc:101158912]) HSP 1 Score: 157.532 bits (397), Expect = 5.440e-47 Identity = 74/108 (68.52%), Postives = 87/108 (80.56%), Query Frame = 3
Query: 687 GLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSV 1010
GLHCDFACLMFK+L +KPS E V ++I+ AV IE+EFLT+ALPV LIGMN E M +YIEFVADRLL+ELG K + ENP DFM+NI ++GKTNFFEKRVGEY V
Sbjct: 17 GLHCDFACLMFKHLVNKPSSETVTEIIRNAVEIEQEFLTEALPVKLIGMNCELMKQYIEFVADRLLLELGFSKIYRAENPFDFMENISLEGKTNFFEKRVGEYQRMGV 124
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Planmine SMEST
Match: SMESG000079368.1 (SMESG000079368.1) HSP 1 Score: 621.698 bits (1602), Expect = 0.000e+0 Identity = 316/316 (100.00%), Postives = 316/316 (100.00%), Query Frame = 3
Query: 93 MEILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHKFDDVN 1040
MEILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHKFDDVN
Sbjct: 1 MEILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHKFDDVN 316
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Planmine SMEST
Match: SMESG000044188.1 (SMESG000044188.1) HSP 1 Score: 621.698 bits (1602), Expect = 0.000e+0 Identity = 316/316 (100.00%), Postives = 316/316 (100.00%), Query Frame = 3
Query: 93 MEILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHKFDDVN 1040
MEILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHKFDDVN
Sbjct: 1 MEILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLFNAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHKFDDVN 316
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Planmine SMEST
Match: SMESG000044184.1 (SMESG000044184.1) HSP 1 Score: 258.455 bits (659), Expect = 4.442e-86 Identity = 124/127 (97.64%), Postives = 125/127 (98.43%), Query Frame = 3
Query: 660 SNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHKFDDVN 1040
+NELISRDEGLHCDFACLMFKYLSSKPS EQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKR GEYSMSSVEDKHKFDDVN
Sbjct: 34 NNELISRDEGLHCDFACLMFKYLSSKPSSEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRCGEYSMSSVEDKHKFDDVN 160 HSP 2 Score: 55.0694 bits (131), Expect = 6.757e-9 Identity = 25/25 (100.00%), Postives = 25/25 (100.00%), Query Frame = 3
Query: 243 MNDDERYFITHVLAFFAASDGIVNE 317
MNDDERYFITHVLAFFAASDGIVNE
Sbjct: 1 MNDDERYFITHVLAFFAASDGIVNE 25
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Planmine SMEST
Match: SMESG000044184.1 (SMESG000044184.1) HSP 1 Score: 259.61 bits (662), Expect = 4.152e-85 Identity = 124/126 (98.41%), Postives = 124/126 (98.41%), Query Frame = 3
Query: 663 NELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRVGEYSMSSVEDKHKFDDVN 1040
NELISRDEGLHCDFACLMFKYLSSKPS EQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKR GEYSMSSVEDKHKFDDVN
Sbjct: 137 NELISRDEGLHCDFACLMFKYLSSKPSSEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENPLDFMDNICIDGKTNFFEKRCGEYSMSSVEDKHKFDDVN 262
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Planmine SMEST
Match: SMESG000014842.1 (SMESG000014842.1) HSP 1 Score: 82.0333 bits (201), Expect = 1.584e-17 Identity = 65/278 (23.38%), Postives = 127/278 (45.68%), Query Frame = 3
Query: 96 EILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKMNDDERYFITHVLAFFAASDGIVNENLVERFIQEVKIPEAEAFYSFQIAIENIHSEMYSLLIDSYVTDTETKNKLF-NAIETMPCVQKKAQWALRWISDKKSTFGTRVVAFAAVEXXXXXXXXXXXXWLKKRGLMPGLCFSNELISRDEGLHCDFACLMFKYLSSKPSPEQVLDLIKEAVGIEKEFLTDALPVSLIGMNAESMCEYIEFVADRLLVELGCDKFWNTENP 926
E LL ++ R IQY DI+ + S F+ + + + ER I +L +++ + ++L+ + +++IPEA F+ FQI + H E++S+L+ S K+ L N IE + + + +FG R++ ++A+E I S + L K + L + + D+ + F ++F++ +KP+ + +IK+ V E EFL + + S+ N + E+++F AD++ + + ENP
Sbjct: 24 EPLLISNEKRFVLFPIQYNDIYAAYQVISSKFYIPQQ--FGTETYSLNSLPIGEREIIERILLYWSYYN---EQSLIFKMNNDIQIPEARCFFGFQINSQINHRELFSILLRS----VNYKHDLMDNKIELLTNLLEN------------ESFGGRLITYSAMESICISSLYILKMLLLKSDELKYLIIRIDAVLNDKSEYTKFGAILFRHCINKPNESKFHSIIKQIVEAEIEFLVNIIGSSICSFNQSPLSEFVQFEADKICDLFKFQRIYKGENP 280 The following BLAST results are available for this feature:
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 3
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 3
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of ribonucleoside diphosphate reductase subunit M2-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30010115 ID=SMED30010115|Name=ribonucleoside diphosphate reductase subunit M2-2|organism=Schmidtea mediterranea sexual|type=transcript|length=1127bpback to top protein sequence of SMED30010115-orf-1 >SMED30010115-orf-1 ID=SMED30010115-orf-1|Name=SMED30010115-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=322bp MEILLTEDKSRIGFLNIQYEDIWEMFNKARSSFWTVNEVNLSKDFAHWKKback to top Aliases
The feature 'ribonucleoside diphosphate reductase subunit M2-2' has the following synonyms
Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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