Homeobox domain-containing protein

Overview
NameHomeobox domain-containing protein
Smed IDSMED30010086
Length (bp)1089
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Homeobox domain-containing protein (SMED30010086) t-SNE clustered cells

Violin plots show distribution of expression levels for Homeobox domain-containing protein (SMED30010086) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Homeobox domain-containing protein (SMED30010086) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Homeobox domain-containing protein (SMED30010086) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30010086

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
central nervous systemSMED30010086h1SMcG0007216 SMED30010086smed_20140614PMID:29100657
Cheng et al., 2018		whole organism asexual adult fluorescence in situ hybridization evidence
X1 cellSMED30010086h1SMcG0007216 SMED30010086smed_20140614PMID:29100657
Cheng et al., 2018		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30010086h1SMcG0007216 dd_Smed_v4_16007_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30010086h1SMcG0007216 dd_Smed_v4_16007_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30010086h1SMcG0007216 dd_Smed_v4_16007_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
non-ciliated neuronSMED30010086h1SMcG0007216 dd_Smed_v4_16007_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30010086h1SMcG0007216 dd_Smed_v4_16007_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30010086h1SMcG0007216 dd_Smed_v6_16007_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: BARHL2 (BarH like homeobox 2 [Source:HGNC Symbol;Acc:HGNC:954])

HSP 1 Score: 154.836 bits (390), Expect = 5.102e-43
Identity = 72/95 (75.79%), Postives = 87/95 (91.58%), Query Frame = 2 
Query:  533 KSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPA 817
            ++KKPRKARTAF+D QLN+LER+F+RQKYLSVQDRM+LA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+   +PY+ YHP+
Sbjct:  228 RAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPYF-YHPS 320
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: BARHL1 (BarH like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:953])

HSP 1 Score: 150.984 bits (380), Expect = 4.306e-42
Identity = 74/105 (70.48%), Postives = 91/105 (86.67%), Query Frame = 2 
Query:  539 KKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIA 853
            KKPRKARTAFTD QL +LER+F+RQKYLSVQDRMELA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+   +PY  ++P  Q++++N++  A
Sbjct:  176 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYP--QSLVSNLDPGA 275
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: BARHL1 (BarH like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:953])

HSP 1 Score: 150.984 bits (380), Expect = 4.306e-42
Identity = 74/105 (70.48%), Postives = 91/105 (86.67%), Query Frame = 2 
Query:  539 KKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIA 853
            KKPRKARTAFTD QL +LER+F+RQKYLSVQDRMELA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+   +PY  ++P  Q++++N++  A
Sbjct:  176 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYP--QSLVSNLDPGA 275
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: BARX1 (BARX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:955])

HSP 1 Score: 88.5817 bits (218), Expect = 1.334e-19
Identity = 65/199 (32.66%), Postives = 93/199 (46.73%), Query Frame = 2 
Query:  188 GSIGSCQAGKPEDLIDEK--KFKSGFMINDILSHD-------------------KLGVNVNDFAVIPVLNRSHCIPAKHDLIFDCSSQQLK-SHYKSPINSFYRWLNHVDPVNSPEKEDEDEYSDFLGSDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKR 718
            G  G+ + G PE   D +  +++S FMI +IL+                     K GV     A  P  +    + A+   +F      L  S   S + +    L       +P    E +    L +       +K+KK R++RT FT+LQL  LE+ F++QKYLS  DR++LA  L LS  QVKTWYQNRR KWK+
Sbjct:    5 GEPGAARFGPPEGCADHRPHRYRS-FMIEEILTEPPGPKGAAPAAAAAAAGELLKFGVQAL-LAARPFHSHLAVLKAEQAAVFKFPLAPLGCSGLSSALLAAGPGLPGA--AGAPHLPLELQLRGKLEAAGPGEPGTKAKKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKK 199
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: TLX1 (T cell leukemia homeobox 1 [Source:HGNC Symbol;Acc:HGNC:5056])

HSP 1 Score: 89.7373 bits (221), Expect = 1.416e-19
Identity = 47/99 (47.47%), Postives = 63/99 (63.64%), Query Frame = 2 
Query:  437 LNHVDPVNSPEKEDEDEYSD--FLGSDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTA 727
            +N++  +  P  E    Y+   F G   Q+    K KKPR   T+FT LQ+ ELE+ F RQKYL+  +R  LA  L+++D QVKTW+QNRRTKW+RQTA
Sbjct:  166 VNNLTGLTFPWMESNRRYTKDRFTGHPYQNRTPPKKKKPR---TSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTA 261
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: ceh-31 (Homeobox protein ceh-31 [Source:UniProtKB/Swiss-Prot;Acc:Q22910])

HSP 1 Score: 149.443 bits (376), Expect = 1.368e-42
Identity = 68/92 (73.91%), Postives = 81/92 (88.04%), Query Frame = 2 
Query:  536 SKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYH 811
            SKK RKART FTD QL ELE  F++QKYLSVQDRMELA+R+ L+DTQVKTWYQNRRTKWKRQ +VG++LL +AGN AAVQ++L+TNPYWA +
Sbjct:   91 SKKARKARTIFTDKQLQELENTFEKQKYLSVQDRMELAHRMGLTDTQVKTWYQNRRTKWKRQASVGMDLLHDAGNMAAVQQLLRTNPYWANY 182
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: ceh-30 (Homeobox protein ceh-30 [Source:UniProtKB/Swiss-Prot;Acc:Q22909])

HSP 1 Score: 140.584 bits (353), Expect = 1.713e-39
Identity = 70/130 (53.85%), Postives = 88/130 (67.69%), Query Frame = 2 
Query:  452 PVNSPEKEDEDEYSDFLGSDSQSHDRSKS------------KKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWA 805
            P NS    D D     + SD  +  R+ S            KK RKART FTD QL ELE  F++QKYLSVQDRM+LA+R+ L+DTQVKTWYQNRRTKWKRQ   G++LL+E GN +AVQ +++++PYWA
Sbjct:   52 PNNSSHSNDHDPSPQSIKSDFSTSPRASSPGGDRMGSPGSCKKSRKARTIFTDKQLQELENTFEKQKYLSVQDRMDLAHRMGLTDTQVKTWYQNRRTKWKRQATSGMDLLSEPGNLSAVQNLIRSSPYWA 181
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: ceh-30 (Homeobox protein ceh-30 [Source:UniProtKB/Swiss-Prot;Acc:Q22909])

HSP 1 Score: 140.584 bits (353), Expect = 1.713e-39
Identity = 70/130 (53.85%), Postives = 88/130 (67.69%), Query Frame = 2 
Query:  452 PVNSPEKEDEDEYSDFLGSDSQSHDRSKS------------KKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWA 805
            P NS    D D     + SD  +  R+ S            KK RKART FTD QL ELE  F++QKYLSVQDRM+LA+R+ L+DTQVKTWYQNRRTKWKRQ   G++LL+E GN +AVQ +++++PYWA
Sbjct:   52 PNNSSHSNDHDPSPQSIKSDFSTSPRASSPGGDRMGSPGSCKKSRKARTIFTDKQLQELENTFEKQKYLSVQDRMDLAHRMGLTDTQVKTWYQNRRTKWKRQATSGMDLLSEPGNLSAVQNLIRSSPYWA 181
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: ceh-19 (Homeobox protein ceh-19 [Source:UniProtKB/Swiss-Prot;Acc:P26797])

HSP 1 Score: 78.1814 bits (191), Expect = 8.977e-17
Identity = 39/82 (47.56%), Postives = 54/82 (65.85%), Query Frame = 2 
Query:  485 EYSDFLGSDSQSHDRSKSKKP---RKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQ 721
            E    LG  ++ HD  +S+K    RK R A++  QL+ LE  F   KYLSV  R++L+  L L++TQ+KTW+QNRRTKWK+Q
Sbjct:   71 ELQMLLGVSARKHDYKRSRKSVCERKPRQAYSARQLDRLETEFQTDKYLSVNKRIQLSQTLNLTETQIKTWFQNRRTKWKKQ 152
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: tab-1 (pep chromosome:WBcel235:II:6803758:6804761:1 gene:WBGene00006380.1 transcript:F31E8.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tab-1)

HSP 1 Score: 77.7962 bits (190), Expect = 1.170e-16
Identity = 37/57 (64.91%), Postives = 45/57 (78.95%), Query Frame = 2 
Query:  548 RKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKR 718
            RKART F+D QL  LER F+ Q+YLS  +R+ELAN L LS+TQVKTW+QNRR K K+
Sbjct:  118 RKARTVFSDQQLQGLERRFESQRYLSTPERIELANALNLSETQVKTWFQNRRMKHKK 174
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: B-H2 (gene:FBgn0004854 transcript:FBtr0334458)

HSP 1 Score: 144.05 bits (362), Expect = 5.262e-40
Identity = 72/94 (76.60%), Postives = 78/94 (82.98%), Query Frame = 2 
Query:  539 KKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRIL-QTNPY---WAY 808
            KK RKARTAFTD QL  LE++F+RQKYLSVQDRMELAN+L LSD QVKTWYQNRRTKWKRQTAVGLELLAEAGN+AA QR+     PY   W Y
Sbjct:   36 KKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGATPYLSAWPY 129
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: B-H1 (gene:FBgn0011758 transcript:FBtr0074430)

HSP 1 Score: 146.362 bits (368), Expect = 4.217e-39
Identity = 73/107 (68.22%), Postives = 85/107 (79.44%), Query Frame = 2 
Query:  479 EDEYSDFLGSDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPY 799
            +D+  + + S S S     SKK RKARTAFTD QL  LE++F+RQKYLSVQ+R ELA++L LSD QVKTWYQNRRTKWKRQTAVGLELLAEAGNFAA QR+   +PY
Sbjct:  277 KDDDGNSVKSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGSPY 383
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: B-H2 (gene:FBgn0004854 transcript:FBtr0074429)

HSP 1 Score: 146.362 bits (368), Expect = 1.152e-38
Identity = 72/94 (76.60%), Postives = 78/94 (82.98%), Query Frame = 2 
Query:  539 KKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRIL-QTNPY---WAY 808
            KK RKARTAFTD QL  LE++F+RQKYLSVQDRMELAN+L LSD QVKTWYQNRRTKWKRQTAVGLELLAEAGN+AA QR+     PY   W Y
Sbjct:  378 KKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGATPYLSAWPY 471
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: CG11085 (gene:FBgn0030408 transcript:FBtr0073656)

HSP 1 Score: 91.2781 bits (225), Expect = 1.191e-20
Identity = 46/69 (66.67%), Postives = 52/69 (75.36%), Query Frame = 2 
Query:  539 KKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELL 745
            +KPR+ RTAFT  QL  LER F  QKYLSV DR ++A  L LS+TQVKTWYQNRRTKWKRQ  + LE L
Sbjct:  158 RKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQL 226
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: C15 (gene:FBgn0004863 transcript:FBtr0084111)

HSP 1 Score: 84.7297 bits (208), Expect = 4.319e-18
Identity = 43/87 (49.43%), Postives = 58/87 (66.67%), Query Frame = 2 
Query:  500 LGSDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGN 760
            +G   Q+    K KKPR   T+FT +Q+ ELE+ F +QKYL+  +R  LA  L+++D QVKTW+QNRRTKW+RQTA   E   +A N
Sbjct:  205 IGHPYQNRTPPKRKKPR---TSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQAAN 288
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: barhl1a (BarH-like homeobox 1a [Source:ZFIN;Acc:ZDB-GENE-050417-212])

HSP 1 Score: 153.68 bits (387), Expect = 1.455e-43
Identity = 86/165 (52.12%), Postives = 115/165 (69.70%), Query Frame = 2 
Query:  362 DLIFDCSSQQLKSHYKSPINSFYRWLNHVDPVNSPEKEDED----EYSDFLGSDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANME 844
            D++ DC      + Y S   S     + +D ++S    D +    + +D   S S+    S+ KKPRKARTAFTD QL +LER+F+RQKYLSVQDRMELA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+   +PY  ++P  Q++++N++
Sbjct:   90 DILADCKPLAACAPYSSTGQSAQDAEDCMDKLHSNSSSDSEYRVKDEADREISSSRDSPNSRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYP--QSLVSNLD 249
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: barhl2 (BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050913-153])

HSP 1 Score: 155.221 bits (391), Expect = 1.673e-43
Identity = 73/95 (76.84%), Postives = 87/95 (91.58%), Query Frame = 2 
Query:  533 KSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPA 817
            +SKKPRKARTAF+D QLN+LER+F+RQKYLSVQDRM+LA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+  + PY+ YHP+
Sbjct:  205 RSKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHPS 297
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: barhl2 (BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050913-153])

HSP 1 Score: 155.221 bits (391), Expect = 1.673e-43
Identity = 73/95 (76.84%), Postives = 87/95 (91.58%), Query Frame = 2 
Query:  533 KSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPA 817
            +SKKPRKARTAF+D QLN+LER+F+RQKYLSVQDRM+LA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+  + PY+ YHP+
Sbjct:  205 RSKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHPS 297
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: barhl2 (BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050913-153])

HSP 1 Score: 155.221 bits (391), Expect = 1.673e-43
Identity = 73/95 (76.84%), Postives = 87/95 (91.58%), Query Frame = 2 
Query:  533 KSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPA 817
            +SKKPRKARTAF+D QLN+LER+F+RQKYLSVQDRM+LA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+  + PY+ YHP+
Sbjct:  205 RSKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHPS 297
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: barhl1a (BarH-like homeobox 1a [Source:ZFIN;Acc:ZDB-GENE-050417-212])

HSP 1 Score: 153.295 bits (386), Expect = 1.704e-43
Identity = 86/165 (52.12%), Postives = 115/165 (69.70%), Query Frame = 2 
Query:  362 DLIFDCSSQQLKSHYKSPINSFYRWLNHVDPVNSPEKEDED----EYSDFLGSDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANME 844
            D++ DC      + Y S   S     + +D ++S    D +    + +D   S S+    S+ KKPRKARTAFTD QL +LER+F+RQKYLSVQDRMELA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+  + PY  ++P  Q++++N++
Sbjct:   90 DILADCKPLAACAPYSSTGQSAQDAEDCMDKLHSNSSSDSEYRVKDEADREISSSRDSPNSRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PY--FYP--QSLVSNLD 249
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: BARHL2 (BarH like homeobox 2 [Source:NCBI gene;Acc:100493839])

HSP 1 Score: 154.451 bits (389), Expect = 5.294e-43
Identity = 79/128 (61.72%), Postives = 98/128 (76.56%), Query Frame = 2 
Query:  467 EKEDEDEYSDFLG-----------SDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPA 817
            EK  ED ++D  G           + S+     ++KKPRKARTAF+D QLN+LER+F+RQKYLSVQDRM+LA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+  + PY+ YHP+
Sbjct:  174 EKIREDLHTDIKGHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHPS 299
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: BARHL2 (BarH like homeobox 2 [Source:NCBI gene;Acc:100493839])

HSP 1 Score: 154.066 bits (388), Expect = 5.419e-43
Identity = 79/128 (61.72%), Postives = 98/128 (76.56%), Query Frame = 2 
Query:  467 EKEDEDEYSDFLG-----------SDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPA 817
            EK  ED ++D  G           + S+     ++KKPRKARTAF+D QLN+LER+F+RQKYLSVQDRM+LA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+  + PY+ YHP+
Sbjct:  167 EKIREDLHTDIKGHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHPS 292
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: pdlim7 (PDZ and LIM domain 7 [Source:Xenbase;Acc:XB-GENE-5860425])

HSP 1 Score: 149.443 bits (376), Expect = 1.594e-41
Identity = 75/113 (66.37%), Postives = 94/113 (83.19%), Query Frame = 2 
Query:  506 SDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANME 844
            S S+     + KKPRKARTAFTD QL +LER+F+RQKYLSVQDRMELA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+   +PY  ++P  Q++++N++
Sbjct:  165 SSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYP--QSLVSNLD 272
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: BARX1 (BARX homeobox 1 [Source:NCBI gene;Acc:100491751])

HSP 1 Score: 88.5817 bits (218), Expect = 7.877e-20
Identity = 42/73 (57.53%), Postives = 52/73 (71.23%), Query Frame = 2 
Query:  500 LGSDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKR 718
            L S       SK+KK R++RT FT+LQL  LE+ F++QKYLS  DR++LA  L LS  QVKTWYQNRR KWK+
Sbjct:  125 LESSVSEQGGSKAKKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKK 197
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: soga1 (suppressor of glucose, autophagy associated 1 [Source:Xenbase;Acc:XB-GENE-6049995])

HSP 1 Score: 87.8113 bits (216), Expect = 1.286e-19
Identity = 43/76 (56.58%), Postives = 55/76 (72.37%), Query Frame = 2 
Query:  500 LGSDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTA 727
            +G   Q+    K KKPR   T+F+ LQ+ ELE+ F RQKYL+  +R  LA  LR+SD+QVKTW+QNRRTKW+RQTA
Sbjct:   94 IGHPYQNRTPPKRKKPR---TSFSRLQICELEKRFHRQKYLASAERASLAKALRMSDSQVKTWFQNRRTKWRRQTA 166
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Barhl2 (BarH like homeobox 2 [Source:MGI Symbol;Acc:MGI:1859314])

HSP 1 Score: 154.836 bits (390), Expect = 3.187e-43
Identity = 72/95 (75.79%), Postives = 87/95 (91.58%), Query Frame = 2 
Query:  533 KSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPA 817
            ++KKPRKARTAF+D QLN+LER+F+RQKYLSVQDRM+LA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+  + PY+ YHP+
Sbjct:  225 RAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHPS 317
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Barhl1 (BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:1859288])

HSP 1 Score: 150.214 bits (378), Expect = 5.105e-42
Identity = 74/105 (70.48%), Postives = 91/105 (86.67%), Query Frame = 2 
Query:  539 KKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIA 853
            KKPRKARTAFTD QL +LER+F+RQKYLSVQDRMELA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+   +PY  ++P  Q++++N++  A
Sbjct:  176 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYP--QSLVSNLDPGA 275
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Barhl1 (BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:1859288])

HSP 1 Score: 150.214 bits (378), Expect = 5.105e-42
Identity = 74/105 (70.48%), Postives = 91/105 (86.67%), Query Frame = 2 
Query:  539 KKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIA 853
            KKPRKARTAFTD QL +LER+F+RQKYLSVQDRMELA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+   +PY  ++P  Q++++N++  A
Sbjct:  176 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYP--QSLVSNLDPGA 275
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Barhl1 (BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:1859288])

HSP 1 Score: 150.214 bits (378), Expect = 5.105e-42
Identity = 74/105 (70.48%), Postives = 91/105 (86.67%), Query Frame = 2 
Query:  539 KKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIA 853
            KKPRKARTAFTD QL +LER+F+RQKYLSVQDRMELA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+   +PY  ++P  Q++++N++  A
Sbjct:  176 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYP--QSLVSNLDPGA 275
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Tlx1 (T cell leukemia, homeobox 1 [Source:MGI Symbol;Acc:MGI:98769])

HSP 1 Score: 89.7373 bits (221), Expect = 1.110e-19
Identity = 47/99 (47.47%), Postives = 63/99 (63.64%), Query Frame = 2 
Query:  437 LNHVDPVNSPEKEDEDEYSD--FLGSDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTA 727
            +N++  +  P  E    Y+   F G   Q+    K KKPR   T+FT LQ+ ELE+ F RQKYL+  +R  LA  L+++D QVKTW+QNRRTKW+RQTA
Sbjct:  169 VNNLTGLTFPWMESNRRYTKDRFTGHPYQNRTPPKKKKPR---TSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTA 264
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8VIB5|BARH2_MOUSE (BarH-like 2 homeobox protein OS=Mus musculus OX=10090 GN=Barhl2 PE=2 SV=2)

HSP 1 Score: 154.836 bits (390), Expect = 2.229e-42
Identity = 72/95 (75.79%), Postives = 87/95 (91.58%), Query Frame = 2 
Query:  533 KSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPA 817
            ++KKPRKARTAF+D QLN+LER+F+RQKYLSVQDRM+LA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+  + PY+ YHP+
Sbjct:  225 RAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHPS 317
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9NY43|BARH2_HUMAN (BarH-like 2 homeobox protein OS=Homo sapiens OX=9606 GN=BARHL2 PE=1 SV=2)

HSP 1 Score: 154.836 bits (390), Expect = 2.450e-42
Identity = 72/95 (75.79%), Postives = 87/95 (91.58%), Query Frame = 2 
Query:  533 KSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPA 817
            ++KKPRKARTAF+D QLN+LER+F+RQKYLSVQDRM+LA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+   +PY+ YHP+
Sbjct:  228 RAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPYF-YHPS 320
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|O88181|BARH2_RAT (BarH-like 2 homeobox protein OS=Rattus norvegicus OX=10116 GN=Barhl2 PE=2 SV=1)

HSP 1 Score: 154.451 bits (389), Expect = 3.456e-42
Identity = 72/95 (75.79%), Postives = 87/95 (91.58%), Query Frame = 2 
Query:  533 KSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPA 817
            ++KKPRKARTAF+D QLN+LER+F+RQKYLSVQDRM+LA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+  + PY+ YHP+
Sbjct:  225 RAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHPS 317
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|Q22910|HM31_CAEEL (Homeobox protein ceh-31 OS=Caenorhabditis elegans OX=6239 GN=ceh-31 PE=4 SV=2)

HSP 1 Score: 149.443 bits (376), Expect = 1.740e-41
Identity = 68/92 (73.91%), Postives = 81/92 (88.04%), Query Frame = 2 
Query:  536 SKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYH 811
            SKK RKART FTD QL ELE  F++QKYLSVQDRMELA+R+ L+DTQVKTWYQNRRTKWKRQ +VG++LL +AGN AAVQ++L+TNPYWA +
Sbjct:   91 SKKARKARTIFTDKQLQELENTFEKQKYLSVQDRMELAHRMGLTDTQVKTWYQNRRTKWKRQASVGMDLLHDAGNMAAVQQLLRTNPYWANY 182
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9BZE3|BARH1_HUMAN (BarH-like 1 homeobox protein OS=Homo sapiens OX=9606 GN=BARHL1 PE=2 SV=1)

HSP 1 Score: 150.984 bits (380), Expect = 2.068e-41
Identity = 74/105 (70.48%), Postives = 91/105 (86.67%), Query Frame = 2 
Query:  539 KKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIA 853
            KKPRKARTAFTD QL +LER+F+RQKYLSVQDRMELA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+   +PY  ++P  Q++++N++  A
Sbjct:  176 KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYP--QSLVSNLDPGA 275
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: G4VLH3 (Putative homeobox protein OS=Schistosoma mansoni OX=6183 GN=Smp_001980 PE=4 SV=1)

HSP 1 Score: 199.134 bits (505), Expect = 1.441e-59
Identity = 91/110 (82.73%), Postives = 101/110 (91.82%), Query Frame = 2 
Query:  530 SKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIARQ 859
            +KSKKPRK+RTAFTDLQLNELE+ FD QKYLSVQDR+ELA RL L+DTQVKTWYQNRRTKWKRQTAVG ELL+EAGNF AVQRILQTNPYWAYHPA QT++ANME I ++
Sbjct:    2 NKSKKPRKSRTAFTDLQLNELEKMFDHQKYLSVQDRIELAERLHLTDTQVKTWYQNRRTKWKRQTAVGFELLSEAGNFVAVQRILQTNPYWAYHPAAQTILANMEAIIKK 111
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: A0A095AHB9 (BarH-like 2 homeobox protein OS=Schistosoma haematobium OX=6185 GN=MS3_01499 PE=4 SV=1)

HSP 1 Score: 199.519 bits (506), Expect = 2.572e-59
Identity = 92/110 (83.64%), Postives = 101/110 (91.82%), Query Frame = 2 
Query:  530 SKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIARQ 859
            +KSKKPRK+RTAFTDLQLNELE+ FD QKYLSVQDR+ELA RL L+DTQVKTWYQNRRTKWKRQTAVG ELLAEAGNF AVQRILQTNPYWAYHPA QT++ANME I ++
Sbjct:    2 NKSKKPRKSRTAFTDLQLNELEKMFDHQKYLSVQDRIELAERLHLTDTQVKTWYQNRRTKWKRQTAVGFELLAEAGNFVAVQRILQTNPYWAYHPAAQTILANMEAIMKK 111
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: A0A564Z5H4 (Homeobox domain-containing protein (Fragment) OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS12607 PE=4 SV=1)

HSP 1 Score: 200.675 bits (509), Expect = 3.823e-59
Identity = 92/118 (77.97%), Postives = 106/118 (89.83%), Query Frame = 2 
Query:  506 SDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIARQ 859
            SD+  H     KKPRKARTAFTD QL+ELERNF+ QKYLSVQDR++LANRL+L+DTQVKTWYQNRRTKWKRQTAVGLELLAE GNF AV+RILQT+PYWA+HPAT+T++ANME IA+Q
Sbjct:   71 SDTSVHQDGVGKKPRKARTAFTDSQLSELERNFESQKYLSVQDRIQLANRLKLNDTQVKTWYQNRRTKWKRQTAVGLELLAETGNFMAVKRILQTSPYWAFHPATETILANMEAIAKQ 188
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: A0A0R3SVR2 (Homeobox domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS9683 PE=4 SV=1)

HSP 1 Score: 199.904 bits (507), Expect = 2.336e-58
Identity = 92/118 (77.97%), Postives = 106/118 (89.83%), Query Frame = 2 
Query:  506 SDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIARQ 859
            SD+  H     KKPRKARTAFTD QL+ELERNF+ QKYLSVQDR++LANRL+L+DTQVKTWYQNRRTKWKRQTAVGLELLAE GNF AV+RILQT+PYWA+HPAT+T++ANME IA+Q
Sbjct:   71 SDTSVHQDGVGKKPRKARTAFTDSQLSELERNFESQKYLSVQDRIQLANRLKLNDTQVKTWYQNRRTKWKRQTAVGLELLAETGNFMAVKRILQTSPYWAFHPATETILANMEAIAKQ 188
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: A0A4Z2CRS5 (BarH-like 2 homeobox protein OS=Schistosoma japonicum OX=6182 GN=EWB00_008059 PE=4 SV=1)

HSP 1 Score: 207.608 bits (527), Expect = 3.462e-58
Identity = 94/113 (83.19%), Postives = 104/113 (92.04%), Query Frame = 2 
Query:  521 HDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIARQ 859
            H+ +KSKKPRK+RTAFTDLQLNELE+ FDRQKYLSVQDR+ELA RL L+DTQVKTWYQNRRTKWKRQTAVG ELLAEAGNF AVQRILQTNPYWAYHPA QT++ANME I ++
Sbjct:  368 HELNKSKKPRKSRTAFTDLQLNELEKMFDRQKYLSVQDRIELAERLHLTDTQVKTWYQNRRTKWKRQTAVGFELLAEAGNFVAVQRILQTNPYWAYHPAAQTILANMEAIMKK 480
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000055685.1 (barH-like 1 homeobox protein [Source:NCBI gene;Acc:103037310])

HSP 1 Score: 150.214 bits (378), Expect = 3.845e-42
Identity = 75/113 (66.37%), Postives = 95/113 (84.07%), Query Frame = 2 
Query:  506 SDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANME 844
            S S+   + + KKPRKARTAFTD QL +LER+F+RQKYLSVQDRMELA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+   +PY  ++P  Q++++N++
Sbjct:  158 SSSRDSPQVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYP--QSLVSNLD 265
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: barhl2 (BarH like homeobox 2 [Source:NCBI gene;Acc:103036087])

HSP 1 Score: 147.902 bits (372), Expect = 7.048e-41
Identity = 70/95 (73.68%), Postives = 85/95 (89.47%), Query Frame = 2 
Query:  533 KSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPA 817
            ++KKPRKARTAF+D QLN+LER+F+RQKYLSVQDRM+LA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAG+++A+QR+  + PY+ Y P 
Sbjct:  210 RTKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGSYSALQRMFPS-PYF-YPPG 302
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: barhl1a (BarH-like homeobox 1a [Source:ZFIN;Acc:ZDB-GENE-050417-212])

HSP 1 Score: 97.8265 bits (242), Expect = 1.541e-23
Identity = 47/55 (85.45%), Postives = 49/55 (89.09%), Query Frame = 2 
Query:  539 KKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRR 703
            KKPRKARTAFTD QL ELER+F RQKYLSVQDRMELA  L L+DTQVKTWYQNRR
Sbjct:  161 KKPRKARTAFTDHQLAELERSFARQKYLSVQDRMELAASLNLTDTQVKTWYQNRR 215
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: barx2 (BARX homeobox 2 [Source:NCBI gene;Acc:103031514])

HSP 1 Score: 90.8929 bits (224), Expect = 1.772e-20
Identity = 65/193 (33.68%), Postives = 96/193 (49.74%), Query Frame = 2 
Query:  203 CQA----GKPEDLIDEKKFKSGFMINDILSHDKLGV--NVNDFAVIPVLN------RSHCIPAK---HDLIFDCSSQQLKSHYKSPINSFYRWLNHVDPVNSPEKEDEDEYSDFLGSDSQS-HDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVG 733
            CQA      P  L   ++    FMI++ILS +       ++ ++V P L        S   P+    + L+   + Q   +    P  S    + H+     P +    E    + S+S++ H   + KKPR++RT FT+LQL  LE+ F +QKYLS  DR++LA  L L+  QVKTWYQNRR KWK+    G
Sbjct:    3 CQAELRGANPGHLAAGRRRYKTFMIDEILSKETCDYFERLSLYSVCPSLVVRPKALHSCSGPSSLRAYPLLSVITRQPPSALPHLPQPSPPGRVTHLPLHPGPGEPQPSETPVSISSESETEHSIPRLKKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKG 195
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: barx1 (homeobox protein BarH-like 1 [Source:NCBI gene;Acc:103035562])

HSP 1 Score: 87.4261 bits (215), Expect = 1.061e-19
Identity = 40/63 (63.49%), Postives = 50/63 (79.37%), Query Frame = 2 
Query:  530 SKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKR 718
            SK+KK R++RT FT+LQL  LE+ F++QKYLS  DR++LA  L LS  QVKTWYQNRR KWK+
Sbjct:  121 SKTKKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKK 183
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: barhl2 (BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050913-153])

HSP 1 Score: 147.517 bits (371), Expect = 2.875e-44
Identity = 69/93 (74.19%), Postives = 80/93 (86.02%), Query Frame = 2 
Query:  533 KSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYH 811
            ++KKPRKARTAF+D QL +LER+F+RQKYLSVQDRMELA+ L LSDTQVKTWYQNRRTKWKRQTAVGLE LAEAG + A+QR+   NP +  H
Sbjct:    1 RAKKPRKARTAFSDHQLTQLERSFERQKYLSVQDRMELASSLSLSDTQVKTWYQNRRTKWKRQTAVGLEFLAEAGTYGALQRLFPNNPLYPPH 93
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: barhl2 (BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050913-153])

HSP 1 Score: 145.976 bits (367), Expect = 1.972e-43
Identity = 68/88 (77.27%), Postives = 78/88 (88.64%), Query Frame = 2 
Query:  533 KSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNP 796
            ++KKPRKARTAF+D QL +LER+F+RQKYLSVQDRMELA+ L LSDTQVKTWYQNRRTKWKRQTAVGLE LAEAG + A+QR+   NP
Sbjct:    1 RAKKPRKARTAFSDHQLTQLERSFERQKYLSVQDRMELASSLSLSDTQVKTWYQNRRTKWKRQTAVGLEFLAEAGTYGALQRLFPNNP 88
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: tlx1 (T cell leukemia homeobox 1 [Source:ZFIN;Acc:ZDB-GENE-021021-2])

HSP 1 Score: 79.337 bits (194), Expect = 4.134e-17
Identity = 38/72 (52.78%), Postives = 50/72 (69.44%), Query Frame = 2 
Query:  500 LGSDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWK 715
            +G   Q+    K KKPR   T+FT LQ+ ELE+ F RQKYL+  +R  LA  L+++D QVKTW+QNRRTKW+
Sbjct:  218 VGHPYQNRTPPKRKKPR---TSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWR 286
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001141.1 (pep scaffold:Pmarinus_7.0:GL478075:36995:38394:-1 gene:ENSPMAG00000001023.1 transcript:ENSPMAT00000001141.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 74.3294 bits (181), Expect = 5.121e-17
Identity = 35/59 (59.32%), Postives = 45/59 (76.27%), Query Frame = 2 
Query:  542 KPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKR 718
            K R+ RTAF+  QL ELER+F RQ+YLS   R ++A+ L L++TQVK W+QNRR KWKR
Sbjct:    2 KCRRPRTAFSSQQLLELERHFSRQRYLSRPQRFQVASALMLTETQVKIWFQNRRMKWKR 60
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001480.1 (pep scaffold:Pmarinus_7.0:GL487501:66:2428:-1 gene:ENSPMAG00000001338.1 transcript:ENSPMAT00000001480.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 74.7146 bits (182), Expect = 6.752e-17
Identity = 36/54 (66.67%), Postives = 43/54 (79.63%), Query Frame = 2 
Query:  548 RKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTK 709
            RKART FTD QL+ LER F RQ+YLS  +R++LA  L LS+TQVKTW+QNRR K
Sbjct:    7 RKARTVFTDSQLSGLERRFVRQRYLSTPERVDLATALGLSETQVKTWFQNRRMK 60
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: EDO43402 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYQ0])

HSP 1 Score: 81.6481 bits (200), Expect = 1.033e-19
Identity = 39/64 (60.94%), Postives = 47/64 (73.44%), Query Frame = 2 
Query:  536 SKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTA 727
            S K R+ RTAFT  QL  LE  F  +KYL++ +R ELA  + LSDTQVKTW+QNRRTKWK+Q A
Sbjct:    8 SSKSRRKRTAFTSSQLKYLEEKFQEKKYLTISERNELAKSMYLSDTQVKTWFQNRRTKWKKQMA 71
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: NK-1 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI80])

HSP 1 Score: 84.3445 bits (207), Expect = 1.270e-18
Identity = 53/139 (38.13%), Postives = 74/139 (53.24%), Query Frame = 2 
Query:  410 SPINSFYRWLNHVDPVNSPEKEDED----------------EYSDFLGSDSQ----------SHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLA 748
            SP   ++ W+N     N P+ + +D                E +D  G D +          S +R+K  KPR+ARTAFT  QL  LE  F   +YLSV +R+ LA  L L++TQVK W+QNRRTKWK+Q   G+++ A
Sbjct:   87 SPTGVWHPWMNATR-YNRPQTKSQDPDKDKASDVDISRSDQETTDAAGEDPKSSSKSKRKRGSTERAKEGKPRRARTAFTYEQLVALENKFKSTRYLSVCERLNLALSLGLTETQVKIWFQNRRTKWKKQNP-GMDVTA 223
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: EDO32495 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUX2])

HSP 1 Score: 77.0258 bits (188), Expect = 4.408e-18
Identity = 35/58 (60.34%), Postives = 46/58 (79.31%), Query Frame = 2 
Query:  548 RKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQ 721
            ++ RTAFT+ Q+ +LE  F + KYLSV  RMELAN L L++TQ+K W+QNRRTKWKR+
Sbjct:    2 KRPRTAFTNEQIKDLEAEFQKSKYLSVSRRMELANSLSLTETQIKIWFQNRRTKWKRK 59
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: EDO35073 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMK0])

HSP 1 Score: 76.2554 bits (186), Expect = 1.339e-17
Identity = 36/64 (56.25%), Postives = 46/64 (71.88%), Query Frame = 2 
Query:  536 SKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTA 727
             ++ RK+RT FTDLQL  LE+ F  QKYL    R +LA  L L++TQVKTW+QNRR KWK++T 
Sbjct:   13 GRRCRKSRTVFTDLQLRVLEKTFSEQKYLDTSSRSKLAQTLGLNETQVKTWFQNRRMKWKKETG 76
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: EDO46621 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPR9])

HSP 1 Score: 83.5741 bits (205), Expect = 1.921e-17
Identity = 36/67 (53.73%), Postives = 47/67 (70.15%), Query Frame = 2 
Query:  527 RSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTA 727
            R +    ++ RTAFT+ Q+ ELE  F + KYL++  R ELAN L LSDTQ+K W+QNRRTK KR+ A
Sbjct: 1037 RKRDPSKKRTRTAFTNTQIRELEAEFQKNKYLTITRRAELANSLELSDTQIKIWFQNRRTKLKRKLA 1103
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: barhl2 (BarH like homeobox 2 [Source:NCBI gene;Acc:101174414])

HSP 1 Score: 155.606 bits (392), Expect = 9.036e-44
Identity = 73/95 (76.84%), Postives = 87/95 (91.58%), Query Frame = 2 
Query:  533 KSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPA 817
            ++KKPRKARTAFTD QLN+LER+F+RQKYLSVQDRM+LA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+  + PY+ YHP+
Sbjct:  202 RTKKPRKARTAFTDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPS-PYF-YHPS 294
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000038356.1 (barH-like 1 homeobox protein [Source:NCBI gene;Acc:100049373])

HSP 1 Score: 150.984 bits (380), Expect = 2.394e-42
Identity = 76/116 (65.52%), Postives = 96/116 (82.76%), Query Frame = 2 
Query:  506 SDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIA 853
            S S+   + + KKPRKARTAFTD QL +LER+F+RQKYLSVQDRMELA  L L+DTQVKTWYQNRRTKWKRQTAVGLELLAEAGN++A+QR+   +PY  ++P  Q++++N++  A
Sbjct:  160 SSSRDSPQVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMF-PSPY--FYP--QSLVSNLDPGA 270
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: barhl1a (BarH like homeobox 1 [Source:NCBI gene;Acc:101158364])

HSP 1 Score: 120.168 bits (300), Expect = 1.795e-31
Identity = 57/70 (81.43%), Postives = 64/70 (91.43%), Query Frame = 2 
Query:  539 KKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLA 748
            KKPRKARTAF+D QL+ LER+F +QKYLSVQDR+ELA  L+LSDTQVKTWYQNRRTKWKRQ+A GLELLA
Sbjct:  138 KKPRKARTAFSDQQLSRLERSFQKQKYLSVQDRIELAASLQLSDTQVKTWYQNRRTKWKRQSAAGLELLA 207
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: tlx1 (T cell leukemia homeobox 1 [Source:NCBI gene;Acc:101163994])

HSP 1 Score: 91.6633 bits (226), Expect = 9.223e-21
Identity = 70/202 (34.65%), Postives = 95/202 (47.03%), Query Frame = 2 
Query:  164 SSENEGTNGSIGSCQAGKPEDLIDEKKFKSGFMINDILSHDKLGVNVNDFAVIPVLNRSHCIPAKHDLIFDCSSQQLKSHYKSPINSFYRWLNHVDPVNSPEKEDEDEYSD--------------FLGSDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTA 727
            +  N G NGS GSC  G P        F  G+ +N  ++    G N+N   VI V       PA   L              S  NS    +N+++ +  P  E    Y+                +G   Q+    K KKPR   T+F+ LQ+ ELE+ F RQKYL+  +R  LA  L+++D QVKTW+QNRRTKW+RQTA
Sbjct:   62 ACANSGYNGSSGSC--GVPS-------FGGGYHMNINVN----GTNMNSSGVIRV-------PAHRPL--------------SGGNSGAPPMNNLNALTFPWMESNRRYTKDRFTVSLSPLTVTRRIGHPYQNRTPPKRKKPR---TSFSRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTA 226
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: barx1 (BARX homeobox 1 [Source:NCBI gene;Acc:110014589])

HSP 1 Score: 89.3521 bits (220), Expect = 3.168e-20
Identity = 42/68 (61.76%), Postives = 51/68 (75.00%), Query Frame = 2 
Query:  530 SKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVG 733
            SKSKK R++RT FT+LQL  LE+ F++QKYLS  DR++LA  L LS  QVKTWYQNRR KWK+    G
Sbjct:  123 SKSKKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKKMVLQG 190
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000030375.1 (SMESG000030375.1)

HSP 1 Score: 497.664 bits (1280), Expect = 6.047e-179
Identity = 261/269 (97.03%), Postives = 262/269 (97.40%), Query Frame = 2 
Query:  146 MNSEGLSSENEGTNGSIGSCQAGKPEDLIDEKKFKSGFMINDILSHDKLGVNVNDFAVIPVLNRSHCIPAKHDLIFDCSSQQLKSHYKSPINSFYRWLNHVDPVNSPEKEDE-DEYSDFLGSDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIARQHQRTTGXXXXXXXXXXXXXXXXXXXXIPAR 949
            MNSEGLSSENEGTNGSIGSCQAGKPEDLIDEKKFKSGFMINDILSHDKLGVNVNDFAVIPVLNRSHCIPAKHDLIFDCSSQQLKSHYKSPINSFYRWLNHVDPVNSPEKE +      FLGSDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIARQHQRTTGSSANSNNNSSTNNPTVPVSSIPAR
Sbjct:    1 MNSEGLSSENEGTNGSIGSCQAGKPEDLIDEKKFKSGFMINDILSHDKLGVNVNDFAVIPVLNRSHCIPAKHDLIFDCSSQQLKSHYKSPINSFYRWLNHVDPVNSPEKEMKMVRLKYFLGSDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIARQHQRTTGSSANSNNNSSTNNPTVPVSSIPAR 269
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000074896.1 (SMESG000074896.1)

HSP 1 Score: 197.593 bits (501), Expect = 1.075e-60
Identity = 96/138 (69.57%), Postives = 111/138 (80.43%), Query Frame = 2 
Query:  467 EKEDEDEYSDFLGSDSQSHDRSKS-----KKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIARQHQ 865
            ++E E   S  LGSD  S+   +      KKPRKARTAFTD QLNELE+NF++QKYLSVQDRMELA +LRL+DTQVKTWYQNRRTKWKRQT VGLELLAEAGNFAAVQRI+QTNPYW YHP  + VI+NM+ + +Q Q
Sbjct:   58 DQESESTGSIDLGSDDVSNCNRRGLSQSGKKPRKARTAFTDHQLNELEKNFEQQKYLSVQDRMELAAKLRLTDTQVKTWYQNRRTKWKRQTTVGLELLAEAGNFAAVQRIIQTNPYWTYHPEARVVISNMDAMLKQQQ 195
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000022963.1 (SMESG000022963.1)

HSP 1 Score: 125.176 bits (313), Expect = 5.939e-34
Identity = 65/119 (54.62%), Postives = 84/119 (70.59%), Query Frame = 2 
Query:  512 SQSHDRSKS---KKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAVQRILQ---TNPYWAYHPATQTVIANMEVI 850
            SQS   SKS   K+PRKARTAFT+ QL ELE++FD+ KYLSVQDR+ELAN L L+DTQVKTWYQNRRTKWKRQT+ G++LL E  N   ++R +     + +W +       ++N+  I
Sbjct:   52 SQSMLASKSFSEKRPRKARTAFTEKQLCELEKSFDKHKYLSVQDRLELANYLELTDTQVKTWYQNRRTKWKRQTSTGVDLLTEGSNVTDLRRSIHYPNNSKFWNWVSNNSASLSNIPSI 170
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000017206.1 (SMESG000017206.1)

HSP 1 Score: 87.8113 bits (216), Expect = 3.448e-20
Identity = 63/171 (36.84%), Postives = 92/171 (53.80%), Query Frame = 2 
Query:  365 LIFDCSSQQLKSHYKSPINSFYRWLNHVDPVNSP----EKEDEDEYSDFLGSDSQSHDRSKSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELLAEAGN---FAAVQRILQT-NPYWAYHPATQTVIANMEVIA 853
            +I   S +  K+H     NS    L+ + P + P    E   +D Y   +G   Q+    K KKPR   T+F   Q+ ELER F RQKYL+  +R +LA  L ++D+QVKTW+QNRRTKW+RQT+   E   +A +         I Q+ NP + Y  +T + I+N++  A
Sbjct:   21 IITSKSEESTKTHS----NSLKHLLSTIFPPSLPRHWIEILRQDRYPRRVGHPYQNRTPPKRKKPR---TSFNRQQIMELERRFHRQKYLASSERCDLAKDLDMTDSQVKTWFQNRRTKWRRQTSEEREAERQAASRYLLTLQNEINQSNNPSFNYTSSTLSAISNLQPWA 184
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000033607.1 (SMESG000033607.1)

HSP 1 Score: 82.4185 bits (202), Expect = 2.479e-17
Identity = 37/64 (57.81%), Postives = 51/64 (79.69%), Query Frame = 2 
Query:  533 KSKKPRKARTAFTDLQLNELERNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQT 724
            K  + RKART F+D QLN LE+ F+ Q+YLS  +R+ELAN+L LS++QVKTW+QNRR K+K+ +
Sbjct:  196 KHSRRRKARTVFSDQQLNGLEKRFESQRYLSTPERIELANQLNLSESQVKTWFQNRRMKYKKTS 259
The following BLAST results are available for this feature:
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
BARHL25.102e-4375.79BarH like homeobox 2 [Source:HGNC Symbol;Acc:HGNC:... [more]
BARHL14.306e-4270.48BarH like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:... [more]
BARHL14.306e-4270.48BarH like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:... [more]
BARX11.334e-1932.66BARX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:955][more]
TLX11.416e-1947.47T cell leukemia homeobox 1 [Source:HGNC Symbol;Acc... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ceh-311.368e-4273.91Homeobox protein ceh-31 [Source:UniProtKB/Swiss-P... [more]
ceh-301.713e-3953.85Homeobox protein ceh-30 [Source:UniProtKB/Swiss-P... [more]
ceh-301.713e-3953.85Homeobox protein ceh-30 [Source:UniProtKB/Swiss-P... [more]
ceh-198.977e-1747.56Homeobox protein ceh-19 [Source:UniProtKB/Swiss-P... [more]
tab-11.170e-1664.91pep chromosome:WBcel235:II:6803758:6804761:1 gene:... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
B-H25.262e-4076.60gene:FBgn0004854 transcript:FBtr0334458[more]
B-H14.217e-3968.22gene:FBgn0011758 transcript:FBtr0074430[more]
B-H21.152e-3876.60gene:FBgn0004854 transcript:FBtr0074429[more]
CG110851.191e-2066.67gene:FBgn0030408 transcript:FBtr0073656[more]
C154.319e-1849.43gene:FBgn0004863 transcript:FBtr0084111[more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
barhl1a1.455e-4352.12BarH-like homeobox 1a [Source:ZFIN;Acc:ZDB-GENE-05... [more]
barhl21.673e-4376.84BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050... [more]
barhl21.673e-4376.84BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050... [more]
barhl21.673e-4376.84BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050... [more]
barhl1a1.704e-4352.12BarH-like homeobox 1a [Source:ZFIN;Acc:ZDB-GENE-05... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
BARHL25.294e-4361.72BarH like homeobox 2 [Source:NCBI gene;Acc:1004938... [more]
BARHL25.419e-4361.72BarH like homeobox 2 [Source:NCBI gene;Acc:1004938... [more]
pdlim71.594e-4166.37PDZ and LIM domain 7 [Source:Xenbase;Acc:XB-GENE-5... [more]
BARX17.877e-2057.53BARX homeobox 1 [Source:NCBI gene;Acc:100491751][more]
soga11.286e-1956.58suppressor of glucose, autophagy associated 1 [Sou... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Barhl23.187e-4375.79BarH like homeobox 2 [Source:MGI Symbol;Acc:MGI:18... [more]
Barhl15.105e-4270.48BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:18... [more]
Barhl15.105e-4270.48BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:18... [more]
Barhl15.105e-4270.48BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:18... [more]
Tlx11.110e-1947.47T cell leukemia, homeobox 1 [Source:MGI Symbol;Acc... [more]
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BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8VIB5|BARH2_MOUSE2.229e-4275.79BarH-like 2 homeobox protein OS=Mus musculus OX=10... [more]
sp|Q9NY43|BARH2_HUMAN2.450e-4275.79BarH-like 2 homeobox protein OS=Homo sapiens OX=96... [more]
sp|O88181|BARH2_RAT3.456e-4275.79BarH-like 2 homeobox protein OS=Rattus norvegicus ... [more]
sp|Q22910|HM31_CAEEL1.740e-4173.91Homeobox protein ceh-31 OS=Caenorhabditis elegans ... [more]
sp|Q9BZE3|BARH1_HUMAN2.068e-4170.48BarH-like 1 homeobox protein OS=Homo sapiens OX=96... [more]
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BLAST of Homeobox domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
G4VLH31.441e-5982.73Putative homeobox protein OS=Schistosoma mansoni O... [more]
A0A095AHB92.572e-5983.64BarH-like 2 homeobox protein OS=Schistosoma haemat... [more]
A0A564Z5H43.823e-5977.97Homeobox domain-containing protein (Fragment) OS=H... [more]
A0A0R3SVR22.336e-5877.97Homeobox domain-containing protein OS=Hymenolepis ... [more]
A0A4Z2CRS53.462e-5883.19BarH-like 2 homeobox protein OS=Schistosoma japoni... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000055685.13.845e-4266.37barH-like 1 homeobox protein [Source:NCBI gene;Acc... [more]
barhl27.048e-4173.68BarH like homeobox 2 [Source:NCBI gene;Acc:1030360... [more]
barhl1a1.541e-2385.45BarH-like homeobox 1a [Source:ZFIN;Acc:ZDB-GENE-05... [more]
barx21.772e-2033.68BARX homeobox 2 [Source:NCBI gene;Acc:103031514][more]
barx11.061e-1963.49homeobox protein BarH-like 1 [Source:NCBI gene;Acc... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
barhl22.875e-4474.19BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050... [more]
barhl21.972e-4377.27BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050... [more]
tlx14.134e-1752.78T cell leukemia homeobox 1 [Source:ZFIN;Acc:ZDB-GE... [more]
ENSPMAT00000001141.15.121e-1759.32pep scaffold:Pmarinus_7.0:GL478075:36995:38394:-1 ... [more]
ENSPMAT00000001480.16.752e-1766.67pep scaffold:Pmarinus_7.0:GL487501:66:2428:-1 gene... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO434021.033e-1960.94Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
NK-11.270e-1838.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO324954.408e-1860.34Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO350731.339e-1756.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO466211.921e-1753.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
barhl29.036e-4476.84BarH like homeobox 2 [Source:NCBI gene;Acc:1011744... [more]
ENSORLT00000038356.12.394e-4265.52barH-like 1 homeobox protein [Source:NCBI gene;Acc... [more]
barhl1a1.795e-3181.43BarH like homeobox 1 [Source:NCBI gene;Acc:1011583... [more]
tlx19.223e-2134.65T cell leukemia homeobox 1 [Source:NCBI gene;Acc:1... [more]
barx13.168e-2061.76BARX homeobox 1 [Source:NCBI gene;Acc:110014589][more]
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BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000030375.16.047e-17997.03SMESG000030375.1[more]
SMESG000074896.11.075e-6069.57SMESG000074896.1[more]
SMESG000022963.15.939e-3454.62SMESG000022963.1[more]
SMESG000017206.13.448e-2036.84SMESG000017206.1[more]
SMESG000033607.12.479e-1757.81SMESG000033607.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010086 ID=SMED30010086|Name=Homeobox domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1089bp
ATAATATTTCCACCAATCAGAATCGCCAGAAAATTCTATGCTCTTTCCTA
GTTTAATCAGAGACCCGCTTTAAAATCAAGTCGGATTTACAAATAAAAAA
ATCCGACTGACAAATGAATATTTAAGTGATTGAAGTTTACTGAAAATGAA
CAGCGAAGGTTTGTCGTCGGAAAATGAAGGAACAAATGGTTCGATTGGTT
CATGTCAGGCGGGAAAACCGGAGGATTTGATCGACGAGAAAAAATTCAAA
TCTGGTTTTATGATCAATGACATTCTCAGTCACGATAAATTGGGAGTTAA
TGTGAACGATTTCGCCGTCATCCCTGTACTGAACCGATCACACTGCATTC
CAGCTAAACACGATCTGATTTTCGATTGTTCCTCACAACAGTTGAAATCT
CACTACAAATCGCCAATTAATTCATTTTATCGATGGCTGAATCACGTTGA
TCCAGTCAACAGTCCGGAAAAAGAGGATGAAGATGAATACTCAGACTTTC
TTGGATCAGATTCTCAATCGCACGACCGATCAAAATCGAAAAAACCAAGA
AAAGCAAGAACAGCTTTTACCGATCTTCAGTTGAATGAGCTGGAACGAAA
CTTTGATCGACAGAAATACCTAAGCGTTCAAGATCGAATGGAGCTGGCAA
ATCGTCTGAGACTAAGTGATACCCAAGTCAAAACCTGGTACCAAAATCGC
AGAACTAAATGGAAACGTCAAACTGCAGTCGGGTTGGAATTGTTAGCTGA
AGCTGGAAATTTCGCTGCTGTGCAAAGAATCCTCCAAACGAATCCCTATT
GGGCATATCATCCAGCAACGCAGACCGTTATTGCAAATATGGAAGTGATT
GCCAGACAACACCAAAGAACAACAGGAAGCAGCGCAAACAGCAATAACAA
CAGCAGTACAAATAATCCCACAGTCCCAGTATCATCAATCCCAGCTAGAA
ACAACTCTAATAACTCTATATCCGTTTCCTTGTGACCATTTCATTAGTAT
GCAAGATGTATTATCAGCCGTTCTTATTGTATATTAGTTAAGATTTTCTT
TATATTTTATTGTCAACCTCCTTCTACATCATACCAATG
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protein sequence of SMED30010086-orf-1

>SMED30010086-orf-1 ID=SMED30010086-orf-1|Name=SMED30010086-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=280bp
MNSEGLSSENEGTNGSIGSCQAGKPEDLIDEKKFKSGFMINDILSHDKLG
VNVNDFAVIPVLNRSHCIPAKHDLIFDCSSQQLKSHYKSPINSFYRWLNH
VDPVNSPEKEDEDEYSDFLGSDSQSHDRSKSKKPRKARTAFTDLQLNELE
RNFDRQKYLSVQDRMELANRLRLSDTQVKTWYQNRRTKWKRQTAVGLELL
AEAGNFAAVQRILQTNPYWAYHPATQTVIANMEVIARQHQRTTGSSANSN
NNSSTNNPTVPVSSIPARNNSNNSISVSL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000103central nervous system
PLANA:0000418head
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR020479Homeobox_metazoa
IPR001356Homeobox_dom
IPR009057Homeobox-like_sf
IPR017970Homeobox_CS
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0043565sequence-specific DNA binding
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus