t-SNARE coiled-coil homology domain-containing protein

Overview
Namet-SNARE coiled-coil homology domain-containing protein
Smed IDSMED30010078
Length (bp)363
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of t-SNARE coiled-coil homology domain-containing protein (SMED30010078) t-SNE clustered cells

Violin plots show distribution of expression levels for t-SNARE coiled-coil homology domain-containing protein (SMED30010078) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of t-SNARE coiled-coil homology domain-containing protein (SMED30010078) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for t-SNARE coiled-coil homology domain-containing protein (SMED30010078) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30010078

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
whole organismSMED30010078 Contig52933newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016
whole organism asexual adult colorimetric in situ hybridization evidence
whole organismSMED30010078 Contig52933uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016
whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Match: BET1L (Bet1 golgi vesicular membrane trafficking protein like [Source:HGNC Symbol;Acc:HGNC:19348])

HSP 1 Score: 70.0922 bits (170), Expect = 3.917e-16
Identity = 28/94 (29.79%), Postives = 58/94 (61.70%), Query Frame = 1
Query:   40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFS 321
            + +L+REN   ++ L++K+  L+S A DI  + + QN ++DG+ S+F+S    +  ++ R   ++++ + NRK++C + +G+   FF+  Y  S
Sbjct:   14 EEILDRENKRMADSLASKVTRLKSLALDIDRDAEDQNRYLDGMDSDFTSMTSLLTGSVKRFSTMARSGQDNRKLLCGMAVGLIVAFFILSYFLS 107          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Match: BET1 (Bet1 golgi vesicular membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:14562])

HSP 1 Score: 65.0846 bits (157), Expect = 3.055e-14
Identity = 33/99 (33.33%), Postives = 58/99 (58.59%), Query Frame = 1
Query:   22 SFRNMNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIF 318
             + N   S  E EN+  +E L +K+  ++S + +I  EVK QN  +  + S+F ST GF+G T+ ++  +S+   S  K++CY++L    +FF+ Y+I 
Sbjct:   19 GYANSGYSACEEENERLTESLRSKVTAIKSLSIEIGHEVKTQNKLLAEMDSQFDSTTGFLGKTMGKLKILSRG--SQTKLLCYMMLFSLFVFFIIYWII 115          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Match: BET1 (Bet1 golgi vesicular membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:14562])

HSP 1 Score: 65.0846 bits (157), Expect = 4.541e-14
Identity = 33/97 (34.02%), Postives = 58/97 (59.79%), Query Frame = 1
Query:   25 FRNMNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYI 315
            + N   S  E EN+  +E L +K+  ++S + +I  EVK QN  +  + S+F ST GF+G T+ ++  +S+   S  K++CY++L    +FF+ Y+I
Sbjct:   35 YANSGYSACEEENERLTESLRSKVTAIKSLSIEIGHEVKTQNKLLAEMDSQFDSTTGFLGKTMGKLKILSRG--SQTKLLCYMMLFSLFVFFIIYWI 129          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Match: BET1L (Bet1 golgi vesicular membrane trafficking protein like [Source:HGNC Symbol;Acc:HGNC:19348])

HSP 1 Score: 60.4622 bits (145), Expect = 1.211e-12
Identity = 24/83 (28.92%), Postives = 51/83 (61.45%), Query Frame = 1
Query:   73 SERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFS 321
            ++ L++K+  L+S A DI  + + QN ++DG+ S+F+S    +  ++ R   ++++ + NRK++C + +G+   FF+  Y  S
Sbjct:    2 ADSLASKVTRLKSLALDIDRDAEDQNRYLDGMDSDFTSMTSLLTGSVKRFSTMARSGQDNRKLLCGMAVGLIVAFFILSYFLS 84          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Match: BET1 (Bet1 golgi vesicular membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:14562])

HSP 1 Score: 47.7506 bits (112), Expect = 9.672e-8
Identity = 24/66 (36.36%), Postives = 38/66 (57.58%), Query Frame = 1
Query:    7 YKSYMSFRNMNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMG 204
            Y +Y  + N   S  E EN+  +E L +K+  ++S + +I  EVK QN  +  + S+F ST GF+G
Sbjct:   15 YGNY-GYANSGYSACEEENERLTESLRSKVTAIKSLSIEIGHEVKTQNKLLAEMDSQFDSTTGFLG 79          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Celegans
Match: nbet-1 (BET1; Nematode homolog of yeast BET1 (Blocked Early in Transport) [Source:UniProtKB/TrEMBL;Acc:G5EEU1])

HSP 1 Score: 54.6842 bits (130), Expect = 9.405e-11
Identity = 30/106 (28.30%), Postives = 59/106 (55.66%), Query Frame = 1
Query:   19 MSFR-------NMNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYI 315
            M+FR       N + + LER ND+    LS+K+  L+     I  +V+ QN  ++ + ++F S++G + +T+ R+  +S+    N  ++CY++L    +FF+ Y +
Sbjct:    1 MAFRGGQMRGPNQDANYLERHNDDLVGGLSSKVAALKRVTIAIGDDVREQNRLLNDMDNDFDSSKGLLQSTMRRLGLVSRAGGKN--MLCYLILFALFVFFVVYCL 104          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Zebrafish
Match: bet1l (Bet1 golgi vesicular membrane trafficking protein-like [Source:NCBI gene;Acc:445493])

HSP 1 Score: 79.7221 bits (195), Expect = 2.579e-20
Identity = 33/94 (35.11%), Postives = 60/94 (63.83%), Query Frame = 1
Query:   46 LLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPL 327
            +L+ EN   +E L++K++ L+S A DI  + + QN+++DG+ S F S  G +  ++ R   + ++ + NRKI+CY+ +G+   FFL YY+ S +
Sbjct:    1 MLDAENKRMAENLASKVSRLKSLAYDIDKDAEEQNAYLDGMDSNFLSATGLLTGSVKRFSTMVRSGRDNRKILCYVSVGLVVAFFLLYYLVSRM 94          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Zebrafish
Match: bet1l (Bet1 golgi vesicular membrane trafficking protein-like [Source:NCBI gene;Acc:445493])

HSP 1 Score: 79.7221 bits (195), Expect = 3.862e-20
Identity = 33/94 (35.11%), Postives = 59/94 (62.77%), Query Frame = 1
Query:   40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFS 321
              +L+ EN   +E L++K++ L+S A DI  + + QN+++DG+ S F S  G +  ++ R   + ++ + NRKI+CY+ +G+   FFL YY+ S
Sbjct:   13 DDMLDAENKRMAENLASKVSRLKSLAYDIDKDAEEQNAYLDGMDSNFLSATGLLTGSVKRFSTMVRSGRDNRKILCYVSVGLVVAFFLLYYLVS 106          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Zebrafish
Match: bet1 (Bet1 golgi vesicular membrane trafficking protein [Source:ZFIN;Acc:ZDB-GENE-040625-3])

HSP 1 Score: 58.5362 bits (140), Expect = 6.466e-12
Identity = 30/92 (32.61%), Postives = 52/92 (56.52%), Query Frame = 1
Query:   43 SLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIF 318
            S+ E EN+   E L  K++ L+  + DI +EVK  N  +  + S+F ST G +G T+ R+  +S+   S  K+ CY++L    +F + Y++ 
Sbjct:   21 SVYEEENEHLQEGLRDKVHALKHLSIDIGNEVKIHNKMLGEMDSDFDSTGGLLGATMGRLKLLSRG--SQTKVYCYMLLFALFVFLVLYWVI 110          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Zebrafish
Match: bet1 (Bet1 golgi vesicular membrane trafficking protein [Source:ZFIN;Acc:ZDB-GENE-040625-3])

HSP 1 Score: 58.5362 bits (140), Expect = 6.466e-12
Identity = 30/92 (32.61%), Postives = 52/92 (56.52%), Query Frame = 1
Query:   43 SLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIF 318
            S+ E EN+   E L  K++ L+  + DI +EVK  N  +  + S+F ST G +G T+ R+  +S+   S  K+ CY++L    +F + Y++ 
Sbjct:   21 SVYEEENEHLQEGLRDKVHALKHLSIDIGNEVKIHNKMLGEMDSDFDSTGGLLGATMGRLKLLSRG--SQTKVYCYMLLFALFVFLVLYWVI 110          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Xenopus
Match: pou3f4 (POU class 3 homeobox 4 [Source:Xenbase;Acc:XB-GENE-479667])

HSP 1 Score: 87.8113 bits (216), Expect = 3.368e-23
Identity = 37/92 (40.22%), Postives = 59/92 (64.13%), Query Frame = 1
Query:   46 LLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFS 321
            +L+ EN   SE LS+K+  L+S A DI  E    N ++DG+ S+F S  G +  ++ R  G++++ + NRK++CY+  G+ GLFFL YY+ S
Sbjct:   16 MLDAENKRLSENLSSKVTRLKSLALDIDKEADDHNKYLDGMDSDFLSVTGLLSGSVKRFTGMARSGRDNRKLLCYVSSGLVGLFFLLYYLVS 107          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Xenopus
Match: nr4a1 (nuclear receptor subfamily 4 group A member 1 [Source:Xenbase;Acc:XB-GENE-483315])

HSP 1 Score: 63.1586 bits (152), Expect = 1.471e-13
Identity = 32/90 (35.56%), Postives = 54/90 (60.00%), Query Frame = 1
Query:   43 SLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYY 312
            S+ E EN+  +E L  K + L+S   DI +EVK+ N  +  + S+F ST G +G T+ R+  +S+   S  K++CY++L    +FF+ Y+
Sbjct:   21 SVYEEENERMTENLKMKASALKSLTIDIGNEVKYHNKMLGEMDSDFDSTGGLLGATMGRLKILSRG--SQAKLLCYMMLFALFVFFVIYW 108          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Xenopus
Match: klhdc3 (kelch domain containing 3 [Source:Xenbase;Acc:XB-GENE-5879387])

HSP 1 Score: 63.1586 bits (152), Expect = 1.471e-13
Identity = 32/90 (35.56%), Postives = 54/90 (60.00%), Query Frame = 1
Query:   43 SLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYY 312
            S+ E EN+  +E L  K + L+S   DI +EVK+ N  +  + S+F ST G +G T+ R+  +S+   S  K++CY++L    +FF+ Y+
Sbjct:   21 SVYEEENERMTENLKMKASALKSLTIDIGNEVKYHNKMLGEMDSDFDSTGGLLGATMGRLKILSRG--SQAKLLCYMMLFALFVFFVIYW 108          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Match: Bet1l (Bet1 golgi vesicular membrane trafficking protein like [Source:MGI Symbol;Acc:MGI:1913128])

HSP 1 Score: 72.7886 bits (177), Expect = 1.857e-17
Identity = 31/101 (30.69%), Postives = 62/101 (61.39%), Query Frame = 1
Query:   40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPLFGSTK 342
            + +L+REN   ++ L++K+  L+S A DI  + + QN ++DG+ S+F+S  G +  ++ R   ++++ + NRK++C    GMA +  + ++I S L   T+
Sbjct:   14 EDILDRENKRMADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTMARSGRDNRKLLC----GMAVVLIVAFFILSYLLSRTR 110          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Match: Bet1 (Bet1 golgi vesicular membrane trafficking protein [Source:MGI Symbol;Acc:MGI:1343104])

HSP 1 Score: 67.781 bits (164), Expect = 2.181e-15
Identity = 34/99 (34.34%), Postives = 59/99 (59.60%), Query Frame = 1
Query:   22 SFRNMNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIF 318
             + N   +  E END  +E L +K+  ++S + +I  EVK+QN  +  + S+F ST GF+G T+ R+  +S+   S  K++CY++L    +FF+ Y+I 
Sbjct:   19 GYANTGYNACEEENDRLTESLRSKVTAIKSLSIEIGHEVKNQNKLLAEMDSQFDSTTGFLGKTMGRLKILSRG--SQTKLLCYMMLFSLFVFFVIYWII 115          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Match: Bet1l (Bet1 golgi vesicular membrane trafficking protein like [Source:MGI Symbol;Acc:MGI:1913128])

HSP 1 Score: 63.1586 bits (152), Expect = 7.381e-14
Identity = 27/90 (30.00%), Postives = 55/90 (61.11%), Query Frame = 1
Query:   73 SERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPLFGSTK 342
            ++ L++K+  L+S A DI  + + QN ++DG+ S+F+S  G +  ++ R   ++++ + NRK++C    GMA +  + ++I S L   T+
Sbjct:    2 ADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTMARSGRDNRKLLC----GMAVVLIVAFFILSYLLSRTR 87          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Match: Gm45785 (predicted gene 45785 [Source:MGI Symbol;Acc:MGI:5804900])

HSP 1 Score: 63.1586 bits (152), Expect = 8.844e-14
Identity = 24/76 (31.58%), Postives = 50/76 (65.79%), Query Frame = 1
Query:   40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMC 267
            + +L+REN   ++ L++K+  L+S A DI  + + QN ++DG+ S+F+S  G +  ++ R   ++++ + NRK++C
Sbjct:   14 EDILDRENKRMADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTMARSGRDNRKLLC 89          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Match: Bet1l (Bet1 golgi vesicular membrane trafficking protein like [Source:MGI Symbol;Acc:MGI:1913128])

HSP 1 Score: 43.1282 bits (100), Expect = 4.153e-6
Identity = 24/101 (23.76%), Postives = 50/101 (49.50%), Query Frame = 1
Query:   40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPLFGSTK 342
            + +L+REN   ++ L++K+  L+S                    S+F+S  G +  ++ R   ++++ + NRK++C    GMA +  + ++I S L   T+
Sbjct:   14 EDILDRENKRMADSLASKVTRLKS-------------------DSDFTSVTGLLTGSVKRFSTMARSGRDNRKLLC----GMAVVLIVAFFILSYLLSRTR 91          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Match: sp|Q68EL3|BET1L_DANRE (BET1-like protein OS=Danio rerio OX=7955 GN=bet1l PE=3 SV=1)

HSP 1 Score: 79.7221 bits (195), Expect = 2.916e-19
Identity = 33/94 (35.11%), Postives = 59/94 (62.77%), Query Frame = 1
Query:   40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFS 321
              +L+ EN   +E L++K++ L+S A DI  + + QN+++DG+ S F S  G +  ++ R   + ++ + NRKI+CY+ +G+   FFL YY+ S
Sbjct:   13 DDMLDAENKRMAENLASKVSRLKSLAYDIDKDAEEQNAYLDGMDSNFLSATGLLTGSVKRFSTMVRSGRDNRKILCYVSVGLVVAFFLLYYLVS 106          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Match: sp|Q3MHP8|BET1L_BOVIN (BET1-like protein OS=Bos taurus OX=9913 GN=BET1L PE=3 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 9.535e-18
Identity = 29/94 (30.85%), Postives = 60/94 (63.83%), Query Frame = 1
Query:   40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFS 321
            + +L+REN   ++ L++K+  L+S A DI  + + QN ++DG+ S+F+S  G +  ++ R   ++++ + NRK++C + +G+   FF+  Y+ S
Sbjct:   14 EEILDRENKRMADSLASKVTRLKSLALDIDRDAEDQNRYLDGMDSDFTSMTGLLTGSVKRFSTMARSGRDNRKLLCGVAVGLIVAFFILSYLLS 107          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5RBX2|BET1L_PONAB (BET1-like protein OS=Pongo abelii OX=9601 GN=BET1L PE=3 SV=1)

HSP 1 Score: 73.559 bits (179), Expect = 6.019e-17
Identity = 29/94 (30.85%), Postives = 59/94 (62.77%), Query Frame = 1
Query:   40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFS 321
            + +L+REN   ++ L++K+  L+S A DI  + + QN ++DG+ S+F+S  G +  ++ R   ++++ + NRK++C + +G+   FF+  Y  S
Sbjct:   14 EEILDRENKRMADNLASKVTRLKSLALDIDKDAEDQNRYLDGMDSDFTSMTGLLTGSVKRFSTMARSGRDNRKLLCGMAVGLIVAFFILSYFLS 107          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Match: sp|O35153|BET1L_MOUSE (BET1-like protein OS=Mus musculus OX=10090 GN=Bet1l PE=3 SV=1)

HSP 1 Score: 72.7886 bits (177), Expect = 1.299e-16
Identity = 31/101 (30.69%), Postives = 62/101 (61.39%), Query Frame = 1
Query:   40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPLFGSTK 342
            + +L+REN   ++ L++K+  L+S A DI  + + QN ++DG+ S+F+S  G +  ++ R   ++++ + NRK++C    GMA +  + ++I S L   T+
Sbjct:   14 EDILDRENKRMADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTMARSGRDNRKLLC----GMAVVLIVAFFILSYLLSRTR 110          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Match: sp|O35152|BET1L_RAT (BET1-like protein OS=Rattus norvegicus OX=10116 GN=Bet1l PE=1 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 2.654e-16
Identity = 30/101 (29.70%), Postives = 62/101 (61.39%), Query Frame = 1
Query:   40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPLFGSTK 342
            + +++REN   ++ L++K+  L+S A DI  + + QN ++DG+ S+F+S  G +  ++ R   ++++ +  RK++C    GMA +  + ++I S LF  T+
Sbjct:   14 EEIVDRENKRMADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTVARSGRDTRKLLC----GMAVVLIVAFFILSYLFSRTR 110          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Match: G7YBS9 (BET1-like protein OS=Clonorchis sinensis OX=79923 GN=CLF_104514 PE=4 SV=1)

HSP 1 Score: 94.3597 bits (233), Expect = 1.240e-22
Identity = 43/92 (46.74%), Postives = 64/92 (69.57%), Query Frame = 1
Query:   37 NQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYY 312
            NQ LLE+EN+ ++E LS K+++L+SFA DI +E K QN+F+D +Q+ F +  G +  TL +VFGI K++  NRK MCY +L M  L  + Y+
Sbjct:    4 NQLLLEQENNRRAEELSHKVSLLKSFAKDIENETKEQNTFLDQMQNSFDTAGGLLSNTLVQVFGIPKHRTKNRKFMCYAILVMVLLIVVAYF 95          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Match: A0A0L8GHU1 (t-SNARE coiled-coil homology domain-containing protein (Fragment) OS=Octopus bimaculoides OX=37653 GN=OCBIM_22033179mg PE=4 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 1.257e-21
Identity = 38/93 (40.86%), Postives = 65/93 (69.89%), Query Frame = 1
Query:   40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIF 318
            +++LE EN    + LS+KI+ L+  A DI S+ K  N ++DG+ ++F S+QG +  ++NR+  +  + K+NRK+MCYI++G++ LFFL YY+ 
Sbjct:    4 EAMLEEENSAHVDGLSSKISRLKGLALDIESDTKDSNRYLDGMGTDFDSSQGLLTGSMNRISHMVNSGKANRKMMCYIIMGLSALFFLSYYLV 96          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Match: A0A0X3PS01 (BET1-like protein OS=Schistocephalus solidus OX=70667 GN=BET1L PE=4 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 5.329e-21
Identity = 41/91 (45.05%), Postives = 59/91 (64.84%), Query Frame = 1
Query:   43 SLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYI 315
            SLLE+EN+ ++E LSTK+ +L+S+A DI  E   QN  +D +QS   S    +G T+ RV GI  N+ +NRK+ CY  L   GLFFL+ ++
Sbjct:    6 SLLEQENNRRAEELSTKVKILKSYAHDIRDEANQQNEVLDKVQSTMDSAGHVLGNTVGRVLGIPANRTNNRKLCCYTPLVFIGLFFLYRFV 96          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Match: A0A5J4NI06 (Blocked early in transport 1 (Fragment) OS=Paragonimus westermani OX=34504 GN=DEA37_0003024 PE=4 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 5.697e-21
Identity = 39/92 (42.39%), Postives = 64/92 (69.57%), Query Frame = 1
Query:   40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYI 315
            Q LLE+EN+ ++E LS K+ +L+SFA DI +E K QN+F+D +++ + +  G +  TL++VFGI K++  NR+ MCY++L +  L    Y+I
Sbjct:    7 QLLLEQENNRRAEELSHKVTILKSFAKDIETETKEQNAFLDQMRNSYETAHGLLSNTLHQVFGIPKHRTQNRRFMCYMILFIVILIVFCYFI 98          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Match: A0A183TD53 (t-SNARE coiled-coil homology domain-containing protein OS=Schistocephalus solidus OX=70667 PE=4 SV=1)

HSP 1 Score: 95.5153 bits (236), Expect = 1.206e-20
Identity = 44/97 (45.36%), Postives = 62/97 (63.92%), Query Frame = 1
Query:   25 FRNMNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYI 315
            F   + SLLE+EN+ ++E LSTK+ +L+S+A DI  E   QN  +D LQS   S    +G T+ RVFGI  N+ +NRK+ CY  L   GLFFL+ ++
Sbjct:  308 FEEASDSLLEQENNRRAEELSTKVKILKSYAHDIRDEANQQNEVLDKLQSTMDSAGHVLGNTVGRVFGIPANRTNNRKLCCYTPLVFIGLFFLYRFV 404          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Cavefish
Match: BET1L (Bet1 golgi vesicular membrane trafficking protein like [Source:NCBI gene;Acc:103035783])

HSP 1 Score: 77.7962 bits (190), Expect = 1.668e-19
Identity = 33/92 (35.87%), Postives = 57/92 (61.96%), Query Frame = 1
Query:   40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYI 315
              +L+ EN   ++ L+TK++ L+S A +I  E   QNS++DG+ S F S  G +  ++ R   + ++ + NRKI+CY+ +G+   FFL YY+
Sbjct:   13 DDMLDEENKRMADNLATKVSRLKSLAFEIDKEADEQNSYLDGMDSNFLSATGLLTGSVKRFSTMVRSSRDNRKILCYVSIGLVLTFFLLYYL 104          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Cavefish
Match: bet1 (Bet1 golgi vesicular membrane trafficking protein [Source:ZFIN;Acc:ZDB-GENE-040625-3])

HSP 1 Score: 66.6254 bits (161), Expect = 1.860e-14
Identity = 33/92 (35.87%), Postives = 54/92 (58.70%), Query Frame = 1
Query:   43 SLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIF 318
            S+ E EN+   E L  K+N L+  + DI +EVKHQN  +  + ++F ST G +G T+ R+  +S+   S  KI CY++L    +F + Y++ 
Sbjct:   21 SVYEEENEHLQEGLRAKVNALKHLSIDIGNEVKHQNKMLGEMDTDFDSTGGLLGATMGRLKLLSRG--SQTKIYCYMLLFALFVFVILYWVI 110          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Sea Lamprey
Match: BET1L (Bet1 golgi vesicular membrane trafficking protein like [Source:HGNC Symbol;Acc:HGNC:19348])

HSP 1 Score: 72.0182 bits (175), Expect = 7.474e-18
Identity = 30/92 (32.61%), Postives = 56/92 (60.87%), Query Frame = 1
Query:   40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYI 315
            + +L+ EN   +E LS+K++ L+SFA +I  E +  N ++DG+ SEF S  G +  ++ R   + ++ + NR++ CY+V  +   F + YY+
Sbjct:   16 EQMLDTENQRATEVLSSKVSRLKSFALEIDKETEEHNQYLDGMDSEFMSVTGLLSGSVKRFSSMVRSGRDNRRLTCYLVAALVISFLVLYYL 107          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Sea Lamprey
Match: BET1L (Bet1 golgi vesicular membrane trafficking protein like [Source:HGNC Symbol;Acc:HGNC:19348])

HSP 1 Score: 71.633 bits (174), Expect = 8.857e-18
Identity = 30/92 (32.61%), Postives = 56/92 (60.87%), Query Frame = 1
Query:   40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYI 315
            + +L+ EN   +E LS+K++ L+SFA +I  E +  N ++DG+ SEF S  G +  ++ R   + ++ + NR++ CY+V  +   F + YY+
Sbjct:   15 EQMLDTENQRATEVLSSKVSRLKSFALEIDKETEEHNQYLDGMDSEFMSVTGLLSGSVKRFSSMVRSGRDNRRLTCYLVAALVISFLVLYYL 106          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Sea Lamprey
Match: bet1 (Bet1 golgi vesicular membrane trafficking protein [Source:ZFIN;Acc:ZDB-GENE-040625-3])

HSP 1 Score: 59.6918 bits (143), Expect = 4.163e-13
Identity = 30/99 (30.30%), Postives = 55/99 (55.56%), Query Frame = 1
Query:   22 SFRNMNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIF 318
            S+    Q + E EN+   + L TK++ L+  + ++ +E+K  NS +  + S F ST G +G T+ R+  IS    S  ++MCY++L    + F+ Y++ 
Sbjct:   19 SYVGGGQRMYEEENEALQDDLRTKVSALKCLSIEMGNEIKVHNSVLSEMDSAFDSTGGLLGATMGRLKKISGG--SQARLMCYLMLFALFVIFVLYWVI 115          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Nematostella
Match: EDO40976 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5H3])

HSP 1 Score: 77.7962 bits (190), Expect = 5.775e-20
Identity = 31/91 (34.07%), Postives = 58/91 (63.74%), Query Frame = 1
Query:   40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYY 312
            ++++E EN+   + L++K++ L+  A DI  E K QN ++ G+  +F S  G +G ++ R+  +    KSNR++MCY++ G+  +FF+ YY
Sbjct:    6 ENIMESENNRMVDNLASKVSRLKGIAIDIERESKQQNDYLGGMGDDFGSASGLLGGSVQRLSNMMGAGKSNRRLMCYLITGLVFIFFVLYY 96          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Nematostella
Match: EDO38457 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCT5])

HSP 1 Score: 50.8322 bits (120), Expect = 2.353e-9
Identity = 30/108 (27.78%), Postives = 53/108 (49.07%), Query Frame = 1
Query:   46 LLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQS-------------------EFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYY 312
            +LE END  +E LS K+  L+S + DI  EV+ QN  +  + S                   +F ++   +  T+ R+  ++K  K + K+MCY++L    +F + +Y
Sbjct:   10 MLEEENDRLTESLSGKVKALKSLSIDIGHEVRTQNKLLQEMLSIDIGHEVRTQNKLLQEMDDDFDTSGSLLSATMGRLSALTK--KGHHKVMCYMILFCFFVFLVAWY 115          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Medaka
Match: BET1L (Bet1 golgi vesicular membrane trafficking protein like [Source:NCBI gene;Acc:101161130])

HSP 1 Score: 77.411 bits (189), Expect = 2.434e-19
Identity = 32/96 (33.33%), Postives = 59/96 (61.46%), Query Frame = 1
Query:   40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPL 327
              +L+ +N   +E L+TK++ L+S A DI  EV  QN ++DG+ S   S  G +  ++ R   + ++ + NR+++CY+ LG+  +FF+ YY+ S +
Sbjct:    9 DDMLDAKNKRLAENLATKVSRLKSLAYDIDREVDDQNDYLDGMDSNMMSATGLLTGSVKRFSTMVRSGRDNRRLLCYVSLGLVLIFFMLYYLVSRI 104          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Medaka
Match: bet1 (Bet1 golgi vesicular membrane trafficking protein [Source:NCBI gene;Acc:101158079])

HSP 1 Score: 71.633 bits (174), Expect = 5.619e-17
Identity = 35/90 (38.89%), Postives = 56/90 (62.22%), Query Frame = 1
Query:   43 SLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYY 312
            S+ E END   E L  K++ L+S   DI +EVK+QN  ++ + S+F ST G +G T+ RV  +S+   S  K++CY++L    +FF+ Y+
Sbjct:   20 SVYEEENDHLQEGLRAKVSALKSLTIDIGTEVKYQNKMLEDMDSDFDSTGGLLGATIGRVKQLSRG--SQTKLLCYMLLFCLFVFFVLYW 107          
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Planmine SMEST
Match: SMESG000033511.1 (SMESG000033511.1)

HSP 1 Score: 211.846 bits (538), Expect = 1.353e-72
Identity = 103/103 (100.00%), Postives = 103/103 (100.00%), Query Frame = 1
Query:   34 MNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPLFGSTK 342
            MNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPLFGSTK
Sbjct:    1 MNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPLFGSTK 103          
The following BLAST results are available for this feature:
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
BET1L3.917e-1629.79Bet1 golgi vesicular membrane trafficking protein ... [more]
BET13.055e-1433.33Bet1 golgi vesicular membrane trafficking protein ... [more]
BET14.541e-1434.02Bet1 golgi vesicular membrane trafficking protein ... [more]
BET1L1.211e-1228.92Bet1 golgi vesicular membrane trafficking protein ... [more]
BET19.672e-836.36Bet1 golgi vesicular membrane trafficking protein ... [more]
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BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
nbet-19.405e-1128.30BET1; Nematode homolog of yeast BET1 (Blocked Earl... [more]
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BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
bet1l2.579e-2035.11Bet1 golgi vesicular membrane trafficking protein-... [more]
bet1l3.862e-2035.11Bet1 golgi vesicular membrane trafficking protein-... [more]
bet16.466e-1232.61Bet1 golgi vesicular membrane trafficking protein ... [more]
bet16.466e-1232.61Bet1 golgi vesicular membrane trafficking protein ... [more]
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BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
pou3f43.368e-2340.22POU class 3 homeobox 4 [Source:Xenbase;Acc:XB-GENE... [more]
nr4a11.471e-1335.56nuclear receptor subfamily 4 group A member 1 [Sou... [more]
klhdc31.471e-1335.56kelch domain containing 3 [Source:Xenbase;Acc:XB-G... [more]
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BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Bet1l1.857e-1730.69Bet1 golgi vesicular membrane trafficking protein ... [more]
Bet12.181e-1534.34Bet1 golgi vesicular membrane trafficking protein ... [more]
Bet1l7.381e-1430.00Bet1 golgi vesicular membrane trafficking protein ... [more]
Gm457858.844e-1431.58predicted gene 45785 [Source:MGI Symbol;Acc:MGI:58... [more]
Bet1l4.153e-623.76Bet1 golgi vesicular membrane trafficking protein ... [more]
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BLAST of t-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q68EL3|BET1L_DANRE2.916e-1935.11BET1-like protein OS=Danio rerio OX=7955 GN=bet1l ... [more]
sp|Q3MHP8|BET1L_BOVIN9.535e-1830.85BET1-like protein OS=Bos taurus OX=9913 GN=BET1L P... [more]
sp|Q5RBX2|BET1L_PONAB6.019e-1730.85BET1-like protein OS=Pongo abelii OX=9601 GN=BET1L... [more]
sp|O35153|BET1L_MOUSE1.299e-1630.69BET1-like protein OS=Mus musculus OX=10090 GN=Bet1... [more]
sp|O35152|BET1L_RAT2.654e-1629.70BET1-like protein OS=Rattus norvegicus OX=10116 GN... [more]
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BLAST of t-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
G7YBS91.240e-2246.74BET1-like protein OS=Clonorchis sinensis OX=79923 ... [more]
A0A0L8GHU11.257e-2140.86t-SNARE coiled-coil homology domain-containing pro... [more]
A0A0X3PS015.329e-2145.05BET1-like protein OS=Schistocephalus solidus OX=70... [more]
A0A5J4NI065.697e-2142.39Blocked early in transport 1 (Fragment) OS=Paragon... [more]
A0A183TD531.206e-2045.36t-SNARE coiled-coil homology domain-containing pro... [more]
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BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
BET1L1.668e-1935.87Bet1 golgi vesicular membrane trafficking protein ... [more]
bet11.860e-1435.87Bet1 golgi vesicular membrane trafficking protein ... [more]
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BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
BET1L7.474e-1832.61Bet1 golgi vesicular membrane trafficking protein ... [more]
BET1L8.857e-1832.61Bet1 golgi vesicular membrane trafficking protein ... [more]
bet14.163e-1330.30Bet1 golgi vesicular membrane trafficking protein ... [more]
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BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO409765.775e-2034.07Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO384572.353e-927.78Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
BET1L2.434e-1933.33Bet1 golgi vesicular membrane trafficking protein ... [more]
bet15.619e-1738.89Bet1 golgi vesicular membrane trafficking protein ... [more]
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BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000033511.11.353e-72100.00SMESG000033511.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010078 ID=SMED30010078|Name=t-SNARE coiled-coil homology domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=363bp
AATCTATATAAATCTTATATGAGTTTTAGAAATATGAATCAATCATTATT
AGAACGAGAAAATGATGAACAAAGTGAAAGGTTGTCCACTAAAATCAACA
TGCTTCGATCATTTGCTACTGATATCCATTCAGAAGTCAAGCATCAAAAT
TCCTTTATCGATGGATTACAATCGGAATTCTCGTCGACTCAAGGATTTAT
GGGCACGACTTTGAATCGAGTATTTGGAATTTCTAAAAATCAGAAATCAA
ATAGAAAAATTATGTGTTATATCGTTCTTGGAATGGCTGGATTGTTTTTT
CTGTTTTATTATATATTTTCGCCTTTATTTGGATCTACTAAATAAATTGA
ATTCAGATTTTTC
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protein sequence of SMED30010078-orf-1

>SMED30010078-orf-1 ID=SMED30010078-orf-1|Name=SMED30010078-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=115bp
NLYKSYMSFRNMNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQN
SFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFF
LFYYIFSPLFGSTK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0015031protein transport
Vocabulary: cellular component
TermDefinition
GO:0030173integral component of Golgi membrane
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000136whole organism
Vocabulary: INTERPRO
TermDefinition
IPR039897BET1
IPR039899BET1_SNARE
IPR000727T_SNARE_dom
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000727Target SNARE coiled-coil homology domainSMARTSM00397tSNARE_6coord: 3..70
e-value: 0.0051
score: 26.0
IPR000727Target SNARE coiled-coil homology domainPROSITEPS50192T_SNAREcoord: 8..70
score: 12.685
NoneNo IPR availableGENE3DG3DSA:1.20.5.110coord: 15..79
e-value: 9.8E-10
score: 40.3
NoneNo IPR availableSUPERFAMILYSSF58038SNARE fusion complexcoord: 5..67
NoneNo IPR availableTMHMMTMhelixcoord: 82..104
IPR039897BET1-like proteinPANTHERPTHR12791GOLGI SNARE BET1-RELATEDcoord: 6..99
IPR039899BET1, SNARE domainCDDcd15853SNARE_Bet1coord: 11..68
e-value: 7.17327E-18
score: 69.0686