t-SNARE coiled-coil homology domain-containing protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30010078 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Match: BET1L (Bet1 golgi vesicular membrane trafficking protein like [Source:HGNC Symbol;Acc:HGNC:19348]) HSP 1 Score: 70.0922 bits (170), Expect = 3.917e-16 Identity = 28/94 (29.79%), Postives = 58/94 (61.70%), Query Frame = 1 Query: 40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFS 321 + +L+REN ++ L++K+ L+S A DI + + QN ++DG+ S+F+S + ++ R ++++ + NRK++C + +G+ FF+ Y S Sbjct: 14 EEILDRENKRMADSLASKVTRLKSLALDIDRDAEDQNRYLDGMDSDFTSMTSLLTGSVKRFSTMARSGQDNRKLLCGMAVGLIVAFFILSYFLS 107
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Match: BET1 (Bet1 golgi vesicular membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:14562]) HSP 1 Score: 65.0846 bits (157), Expect = 3.055e-14 Identity = 33/99 (33.33%), Postives = 58/99 (58.59%), Query Frame = 1 Query: 22 SFRNMNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIF 318 + N S E EN+ +E L +K+ ++S + +I EVK QN + + S+F ST GF+G T+ ++ +S+ S K++CY++L +FF+ Y+I Sbjct: 19 GYANSGYSACEEENERLTESLRSKVTAIKSLSIEIGHEVKTQNKLLAEMDSQFDSTTGFLGKTMGKLKILSRG--SQTKLLCYMMLFSLFVFFIIYWII 115
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Match: BET1 (Bet1 golgi vesicular membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:14562]) HSP 1 Score: 65.0846 bits (157), Expect = 4.541e-14 Identity = 33/97 (34.02%), Postives = 58/97 (59.79%), Query Frame = 1 Query: 25 FRNMNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYI 315 + N S E EN+ +E L +K+ ++S + +I EVK QN + + S+F ST GF+G T+ ++ +S+ S K++CY++L +FF+ Y+I Sbjct: 35 YANSGYSACEEENERLTESLRSKVTAIKSLSIEIGHEVKTQNKLLAEMDSQFDSTTGFLGKTMGKLKILSRG--SQTKLLCYMMLFSLFVFFIIYWI 129
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Match: BET1L (Bet1 golgi vesicular membrane trafficking protein like [Source:HGNC Symbol;Acc:HGNC:19348]) HSP 1 Score: 60.4622 bits (145), Expect = 1.211e-12 Identity = 24/83 (28.92%), Postives = 51/83 (61.45%), Query Frame = 1 Query: 73 SERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFS 321 ++ L++K+ L+S A DI + + QN ++DG+ S+F+S + ++ R ++++ + NRK++C + +G+ FF+ Y S Sbjct: 2 ADSLASKVTRLKSLALDIDRDAEDQNRYLDGMDSDFTSMTSLLTGSVKRFSTMARSGQDNRKLLCGMAVGLIVAFFILSYFLS 84
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Match: BET1 (Bet1 golgi vesicular membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:14562]) HSP 1 Score: 47.7506 bits (112), Expect = 9.672e-8 Identity = 24/66 (36.36%), Postives = 38/66 (57.58%), Query Frame = 1 Query: 7 YKSYMSFRNMNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMG 204 Y +Y + N S E EN+ +E L +K+ ++S + +I EVK QN + + S+F ST GF+G Sbjct: 15 YGNY-GYANSGYSACEEENERLTESLRSKVTAIKSLSIEIGHEVKTQNKLLAEMDSQFDSTTGFLG 79
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Celegans
Match: nbet-1 (BET1; Nematode homolog of yeast BET1 (Blocked Early in Transport) [Source:UniProtKB/TrEMBL;Acc:G5EEU1]) HSP 1 Score: 54.6842 bits (130), Expect = 9.405e-11 Identity = 30/106 (28.30%), Postives = 59/106 (55.66%), Query Frame = 1 Query: 19 MSFR-------NMNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYI 315 M+FR N + + LER ND+ LS+K+ L+ I +V+ QN ++ + ++F S++G + +T+ R+ +S+ N ++CY++L +FF+ Y + Sbjct: 1 MAFRGGQMRGPNQDANYLERHNDDLVGGLSSKVAALKRVTIAIGDDVREQNRLLNDMDNDFDSSKGLLQSTMRRLGLVSRAGGKN--MLCYLILFALFVFFVVYCL 104
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Zebrafish
Match: bet1l (Bet1 golgi vesicular membrane trafficking protein-like [Source:NCBI gene;Acc:445493]) HSP 1 Score: 79.7221 bits (195), Expect = 2.579e-20 Identity = 33/94 (35.11%), Postives = 60/94 (63.83%), Query Frame = 1 Query: 46 LLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPL 327 +L+ EN +E L++K++ L+S A DI + + QN+++DG+ S F S G + ++ R + ++ + NRKI+CY+ +G+ FFL YY+ S + Sbjct: 1 MLDAENKRMAENLASKVSRLKSLAYDIDKDAEEQNAYLDGMDSNFLSATGLLTGSVKRFSTMVRSGRDNRKILCYVSVGLVVAFFLLYYLVSRM 94
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Zebrafish
Match: bet1l (Bet1 golgi vesicular membrane trafficking protein-like [Source:NCBI gene;Acc:445493]) HSP 1 Score: 79.7221 bits (195), Expect = 3.862e-20 Identity = 33/94 (35.11%), Postives = 59/94 (62.77%), Query Frame = 1 Query: 40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFS 321 +L+ EN +E L++K++ L+S A DI + + QN+++DG+ S F S G + ++ R + ++ + NRKI+CY+ +G+ FFL YY+ S Sbjct: 13 DDMLDAENKRMAENLASKVSRLKSLAYDIDKDAEEQNAYLDGMDSNFLSATGLLTGSVKRFSTMVRSGRDNRKILCYVSVGLVVAFFLLYYLVS 106
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Zebrafish
Match: bet1 (Bet1 golgi vesicular membrane trafficking protein [Source:ZFIN;Acc:ZDB-GENE-040625-3]) HSP 1 Score: 58.5362 bits (140), Expect = 6.466e-12 Identity = 30/92 (32.61%), Postives = 52/92 (56.52%), Query Frame = 1 Query: 43 SLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIF 318 S+ E EN+ E L K++ L+ + DI +EVK N + + S+F ST G +G T+ R+ +S+ S K+ CY++L +F + Y++ Sbjct: 21 SVYEEENEHLQEGLRDKVHALKHLSIDIGNEVKIHNKMLGEMDSDFDSTGGLLGATMGRLKLLSRG--SQTKVYCYMLLFALFVFLVLYWVI 110
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Zebrafish
Match: bet1 (Bet1 golgi vesicular membrane trafficking protein [Source:ZFIN;Acc:ZDB-GENE-040625-3]) HSP 1 Score: 58.5362 bits (140), Expect = 6.466e-12 Identity = 30/92 (32.61%), Postives = 52/92 (56.52%), Query Frame = 1 Query: 43 SLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIF 318 S+ E EN+ E L K++ L+ + DI +EVK N + + S+F ST G +G T+ R+ +S+ S K+ CY++L +F + Y++ Sbjct: 21 SVYEEENEHLQEGLRDKVHALKHLSIDIGNEVKIHNKMLGEMDSDFDSTGGLLGATMGRLKLLSRG--SQTKVYCYMLLFALFVFLVLYWVI 110
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Xenopus
Match: pou3f4 (POU class 3 homeobox 4 [Source:Xenbase;Acc:XB-GENE-479667]) HSP 1 Score: 87.8113 bits (216), Expect = 3.368e-23 Identity = 37/92 (40.22%), Postives = 59/92 (64.13%), Query Frame = 1 Query: 46 LLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFS 321 +L+ EN SE LS+K+ L+S A DI E N ++DG+ S+F S G + ++ R G++++ + NRK++CY+ G+ GLFFL YY+ S Sbjct: 16 MLDAENKRLSENLSSKVTRLKSLALDIDKEADDHNKYLDGMDSDFLSVTGLLSGSVKRFTGMARSGRDNRKLLCYVSSGLVGLFFLLYYLVS 107
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Xenopus
Match: nr4a1 (nuclear receptor subfamily 4 group A member 1 [Source:Xenbase;Acc:XB-GENE-483315]) HSP 1 Score: 63.1586 bits (152), Expect = 1.471e-13 Identity = 32/90 (35.56%), Postives = 54/90 (60.00%), Query Frame = 1 Query: 43 SLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYY 312 S+ E EN+ +E L K + L+S DI +EVK+ N + + S+F ST G +G T+ R+ +S+ S K++CY++L +FF+ Y+ Sbjct: 21 SVYEEENERMTENLKMKASALKSLTIDIGNEVKYHNKMLGEMDSDFDSTGGLLGATMGRLKILSRG--SQAKLLCYMMLFALFVFFVIYW 108
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Xenopus
Match: klhdc3 (kelch domain containing 3 [Source:Xenbase;Acc:XB-GENE-5879387]) HSP 1 Score: 63.1586 bits (152), Expect = 1.471e-13 Identity = 32/90 (35.56%), Postives = 54/90 (60.00%), Query Frame = 1 Query: 43 SLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYY 312 S+ E EN+ +E L K + L+S DI +EVK+ N + + S+F ST G +G T+ R+ +S+ S K++CY++L +FF+ Y+ Sbjct: 21 SVYEEENERMTENLKMKASALKSLTIDIGNEVKYHNKMLGEMDSDFDSTGGLLGATMGRLKILSRG--SQAKLLCYMMLFALFVFFVIYW 108
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Match: Bet1l (Bet1 golgi vesicular membrane trafficking protein like [Source:MGI Symbol;Acc:MGI:1913128]) HSP 1 Score: 72.7886 bits (177), Expect = 1.857e-17 Identity = 31/101 (30.69%), Postives = 62/101 (61.39%), Query Frame = 1 Query: 40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPLFGSTK 342 + +L+REN ++ L++K+ L+S A DI + + QN ++DG+ S+F+S G + ++ R ++++ + NRK++C GMA + + ++I S L T+ Sbjct: 14 EDILDRENKRMADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTMARSGRDNRKLLC----GMAVVLIVAFFILSYLLSRTR 110
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Match: Bet1 (Bet1 golgi vesicular membrane trafficking protein [Source:MGI Symbol;Acc:MGI:1343104]) HSP 1 Score: 67.781 bits (164), Expect = 2.181e-15 Identity = 34/99 (34.34%), Postives = 59/99 (59.60%), Query Frame = 1 Query: 22 SFRNMNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIF 318 + N + E END +E L +K+ ++S + +I EVK+QN + + S+F ST GF+G T+ R+ +S+ S K++CY++L +FF+ Y+I Sbjct: 19 GYANTGYNACEEENDRLTESLRSKVTAIKSLSIEIGHEVKNQNKLLAEMDSQFDSTTGFLGKTMGRLKILSRG--SQTKLLCYMMLFSLFVFFVIYWII 115
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Match: Bet1l (Bet1 golgi vesicular membrane trafficking protein like [Source:MGI Symbol;Acc:MGI:1913128]) HSP 1 Score: 63.1586 bits (152), Expect = 7.381e-14 Identity = 27/90 (30.00%), Postives = 55/90 (61.11%), Query Frame = 1 Query: 73 SERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPLFGSTK 342 ++ L++K+ L+S A DI + + QN ++DG+ S+F+S G + ++ R ++++ + NRK++C GMA + + ++I S L T+ Sbjct: 2 ADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTMARSGRDNRKLLC----GMAVVLIVAFFILSYLLSRTR 87
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Match: Gm45785 (predicted gene 45785 [Source:MGI Symbol;Acc:MGI:5804900]) HSP 1 Score: 63.1586 bits (152), Expect = 8.844e-14 Identity = 24/76 (31.58%), Postives = 50/76 (65.79%), Query Frame = 1 Query: 40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMC 267 + +L+REN ++ L++K+ L+S A DI + + QN ++DG+ S+F+S G + ++ R ++++ + NRK++C Sbjct: 14 EDILDRENKRMADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTMARSGRDNRKLLC 89
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Match: Bet1l (Bet1 golgi vesicular membrane trafficking protein like [Source:MGI Symbol;Acc:MGI:1913128]) HSP 1 Score: 43.1282 bits (100), Expect = 4.153e-6 Identity = 24/101 (23.76%), Postives = 50/101 (49.50%), Query Frame = 1 Query: 40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPLFGSTK 342 + +L+REN ++ L++K+ L+S S+F+S G + ++ R ++++ + NRK++C GMA + + ++I S L T+ Sbjct: 14 EDILDRENKRMADSLASKVTRLKS-------------------DSDFTSVTGLLTGSVKRFSTMARSGRDNRKLLC----GMAVVLIVAFFILSYLLSRTR 91
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Match: sp|Q68EL3|BET1L_DANRE (BET1-like protein OS=Danio rerio OX=7955 GN=bet1l PE=3 SV=1) HSP 1 Score: 79.7221 bits (195), Expect = 2.916e-19 Identity = 33/94 (35.11%), Postives = 59/94 (62.77%), Query Frame = 1 Query: 40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFS 321 +L+ EN +E L++K++ L+S A DI + + QN+++DG+ S F S G + ++ R + ++ + NRKI+CY+ +G+ FFL YY+ S Sbjct: 13 DDMLDAENKRMAENLASKVSRLKSLAYDIDKDAEEQNAYLDGMDSNFLSATGLLTGSVKRFSTMVRSGRDNRKILCYVSVGLVVAFFLLYYLVS 106
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Match: sp|Q3MHP8|BET1L_BOVIN (BET1-like protein OS=Bos taurus OX=9913 GN=BET1L PE=3 SV=1) HSP 1 Score: 75.8702 bits (185), Expect = 9.535e-18 Identity = 29/94 (30.85%), Postives = 60/94 (63.83%), Query Frame = 1 Query: 40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFS 321 + +L+REN ++ L++K+ L+S A DI + + QN ++DG+ S+F+S G + ++ R ++++ + NRK++C + +G+ FF+ Y+ S Sbjct: 14 EEILDRENKRMADSLASKVTRLKSLALDIDRDAEDQNRYLDGMDSDFTSMTGLLTGSVKRFSTMARSGRDNRKLLCGVAVGLIVAFFILSYLLS 107
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5RBX2|BET1L_PONAB (BET1-like protein OS=Pongo abelii OX=9601 GN=BET1L PE=3 SV=1) HSP 1 Score: 73.559 bits (179), Expect = 6.019e-17 Identity = 29/94 (30.85%), Postives = 59/94 (62.77%), Query Frame = 1 Query: 40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFS 321 + +L+REN ++ L++K+ L+S A DI + + QN ++DG+ S+F+S G + ++ R ++++ + NRK++C + +G+ FF+ Y S Sbjct: 14 EEILDRENKRMADNLASKVTRLKSLALDIDKDAEDQNRYLDGMDSDFTSMTGLLTGSVKRFSTMARSGRDNRKLLCGMAVGLIVAFFILSYFLS 107
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Match: sp|O35153|BET1L_MOUSE (BET1-like protein OS=Mus musculus OX=10090 GN=Bet1l PE=3 SV=1) HSP 1 Score: 72.7886 bits (177), Expect = 1.299e-16 Identity = 31/101 (30.69%), Postives = 62/101 (61.39%), Query Frame = 1 Query: 40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPLFGSTK 342 + +L+REN ++ L++K+ L+S A DI + + QN ++DG+ S+F+S G + ++ R ++++ + NRK++C GMA + + ++I S L T+ Sbjct: 14 EDILDRENKRMADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTMARSGRDNRKLLC----GMAVVLIVAFFILSYLLSRTR 110
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Match: sp|O35152|BET1L_RAT (BET1-like protein OS=Rattus norvegicus OX=10116 GN=Bet1l PE=1 SV=1) HSP 1 Score: 72.0182 bits (175), Expect = 2.654e-16 Identity = 30/101 (29.70%), Postives = 62/101 (61.39%), Query Frame = 1 Query: 40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPLFGSTK 342 + +++REN ++ L++K+ L+S A DI + + QN ++DG+ S+F+S G + ++ R ++++ + RK++C GMA + + ++I S LF T+ Sbjct: 14 EEIVDRENKRMADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTVARSGRDTRKLLC----GMAVVLIVAFFILSYLFSRTR 110
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Match: G7YBS9 (BET1-like protein OS=Clonorchis sinensis OX=79923 GN=CLF_104514 PE=4 SV=1) HSP 1 Score: 94.3597 bits (233), Expect = 1.240e-22 Identity = 43/92 (46.74%), Postives = 64/92 (69.57%), Query Frame = 1 Query: 37 NQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYY 312 NQ LLE+EN+ ++E LS K+++L+SFA DI +E K QN+F+D +Q+ F + G + TL +VFGI K++ NRK MCY +L M L + Y+ Sbjct: 4 NQLLLEQENNRRAEELSHKVSLLKSFAKDIENETKEQNTFLDQMQNSFDTAGGLLSNTLVQVFGIPKHRTKNRKFMCYAILVMVLLIVVAYF 95
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Match: A0A0L8GHU1 (t-SNARE coiled-coil homology domain-containing protein (Fragment) OS=Octopus bimaculoides OX=37653 GN=OCBIM_22033179mg PE=4 SV=1) HSP 1 Score: 91.6633 bits (226), Expect = 1.257e-21 Identity = 38/93 (40.86%), Postives = 65/93 (69.89%), Query Frame = 1 Query: 40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIF 318 +++LE EN + LS+KI+ L+ A DI S+ K N ++DG+ ++F S+QG + ++NR+ + + K+NRK+MCYI++G++ LFFL YY+ Sbjct: 4 EAMLEEENSAHVDGLSSKISRLKGLALDIESDTKDSNRYLDGMGTDFDSSQGLLTGSMNRISHMVNSGKANRKMMCYIIMGLSALFFLSYYLV 96
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Match: A0A0X3PS01 (BET1-like protein OS=Schistocephalus solidus OX=70667 GN=BET1L PE=4 SV=1) HSP 1 Score: 90.1225 bits (222), Expect = 5.329e-21 Identity = 41/91 (45.05%), Postives = 59/91 (64.84%), Query Frame = 1 Query: 43 SLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYI 315 SLLE+EN+ ++E LSTK+ +L+S+A DI E QN +D +QS S +G T+ RV GI N+ +NRK+ CY L GLFFL+ ++ Sbjct: 6 SLLEQENNRRAEELSTKVKILKSYAHDIRDEANQQNEVLDKVQSTMDSAGHVLGNTVGRVLGIPANRTNNRKLCCYTPLVFIGLFFLYRFV 96
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Match: A0A5J4NI06 (Blocked early in transport 1 (Fragment) OS=Paragonimus westermani OX=34504 GN=DEA37_0003024 PE=4 SV=1) HSP 1 Score: 90.1225 bits (222), Expect = 5.697e-21 Identity = 39/92 (42.39%), Postives = 64/92 (69.57%), Query Frame = 1 Query: 40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYI 315 Q LLE+EN+ ++E LS K+ +L+SFA DI +E K QN+F+D +++ + + G + TL++VFGI K++ NR+ MCY++L + L Y+I Sbjct: 7 QLLLEQENNRRAEELSHKVTILKSFAKDIETETKEQNAFLDQMRNSYETAHGLLSNTLHQVFGIPKHRTQNRRFMCYMILFIVILIVFCYFI 98
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Match: A0A183TD53 (t-SNARE coiled-coil homology domain-containing protein OS=Schistocephalus solidus OX=70667 PE=4 SV=1) HSP 1 Score: 95.5153 bits (236), Expect = 1.206e-20 Identity = 44/97 (45.36%), Postives = 62/97 (63.92%), Query Frame = 1 Query: 25 FRNMNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYI 315 F + SLLE+EN+ ++E LSTK+ +L+S+A DI E QN +D LQS S +G T+ RVFGI N+ +NRK+ CY L GLFFL+ ++ Sbjct: 308 FEEASDSLLEQENNRRAEELSTKVKILKSYAHDIRDEANQQNEVLDKLQSTMDSAGHVLGNTVGRVFGIPANRTNNRKLCCYTPLVFIGLFFLYRFV 404
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Cavefish
Match: BET1L (Bet1 golgi vesicular membrane trafficking protein like [Source:NCBI gene;Acc:103035783]) HSP 1 Score: 77.7962 bits (190), Expect = 1.668e-19 Identity = 33/92 (35.87%), Postives = 57/92 (61.96%), Query Frame = 1 Query: 40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYI 315 +L+ EN ++ L+TK++ L+S A +I E QNS++DG+ S F S G + ++ R + ++ + NRKI+CY+ +G+ FFL YY+ Sbjct: 13 DDMLDEENKRMADNLATKVSRLKSLAFEIDKEADEQNSYLDGMDSNFLSATGLLTGSVKRFSTMVRSSRDNRKILCYVSIGLVLTFFLLYYL 104
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Cavefish
Match: bet1 (Bet1 golgi vesicular membrane trafficking protein [Source:ZFIN;Acc:ZDB-GENE-040625-3]) HSP 1 Score: 66.6254 bits (161), Expect = 1.860e-14 Identity = 33/92 (35.87%), Postives = 54/92 (58.70%), Query Frame = 1 Query: 43 SLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIF 318 S+ E EN+ E L K+N L+ + DI +EVKHQN + + ++F ST G +G T+ R+ +S+ S KI CY++L +F + Y++ Sbjct: 21 SVYEEENEHLQEGLRAKVNALKHLSIDIGNEVKHQNKMLGEMDTDFDSTGGLLGATMGRLKLLSRG--SQTKIYCYMLLFALFVFVILYWVI 110
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Sea Lamprey
Match: BET1L (Bet1 golgi vesicular membrane trafficking protein like [Source:HGNC Symbol;Acc:HGNC:19348]) HSP 1 Score: 72.0182 bits (175), Expect = 7.474e-18 Identity = 30/92 (32.61%), Postives = 56/92 (60.87%), Query Frame = 1 Query: 40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYI 315 + +L+ EN +E LS+K++ L+SFA +I E + N ++DG+ SEF S G + ++ R + ++ + NR++ CY+V + F + YY+ Sbjct: 16 EQMLDTENQRATEVLSSKVSRLKSFALEIDKETEEHNQYLDGMDSEFMSVTGLLSGSVKRFSSMVRSGRDNRRLTCYLVAALVISFLVLYYL 107
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Sea Lamprey
Match: BET1L (Bet1 golgi vesicular membrane trafficking protein like [Source:HGNC Symbol;Acc:HGNC:19348]) HSP 1 Score: 71.633 bits (174), Expect = 8.857e-18 Identity = 30/92 (32.61%), Postives = 56/92 (60.87%), Query Frame = 1 Query: 40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYI 315 + +L+ EN +E LS+K++ L+SFA +I E + N ++DG+ SEF S G + ++ R + ++ + NR++ CY+V + F + YY+ Sbjct: 15 EQMLDTENQRATEVLSSKVSRLKSFALEIDKETEEHNQYLDGMDSEFMSVTGLLSGSVKRFSSMVRSGRDNRRLTCYLVAALVISFLVLYYL 106
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Sea Lamprey
Match: bet1 (Bet1 golgi vesicular membrane trafficking protein [Source:ZFIN;Acc:ZDB-GENE-040625-3]) HSP 1 Score: 59.6918 bits (143), Expect = 4.163e-13 Identity = 30/99 (30.30%), Postives = 55/99 (55.56%), Query Frame = 1 Query: 22 SFRNMNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIF 318 S+ Q + E EN+ + L TK++ L+ + ++ +E+K NS + + S F ST G +G T+ R+ IS S ++MCY++L + F+ Y++ Sbjct: 19 SYVGGGQRMYEEENEALQDDLRTKVSALKCLSIEMGNEIKVHNSVLSEMDSAFDSTGGLLGATMGRLKKISGG--SQARLMCYLMLFALFVIFVLYWVI 115
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Nematostella
Match: EDO40976 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5H3]) HSP 1 Score: 77.7962 bits (190), Expect = 5.775e-20 Identity = 31/91 (34.07%), Postives = 58/91 (63.74%), Query Frame = 1 Query: 40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYY 312 ++++E EN+ + L++K++ L+ A DI E K QN ++ G+ +F S G +G ++ R+ + KSNR++MCY++ G+ +FF+ YY Sbjct: 6 ENIMESENNRMVDNLASKVSRLKGIAIDIERESKQQNDYLGGMGDDFGSASGLLGGSVQRLSNMMGAGKSNRRLMCYLITGLVFIFFVLYY 96
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Nematostella
Match: EDO38457 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCT5]) HSP 1 Score: 50.8322 bits (120), Expect = 2.353e-9 Identity = 30/108 (27.78%), Postives = 53/108 (49.07%), Query Frame = 1 Query: 46 LLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQS-------------------EFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYY 312 +LE END +E LS K+ L+S + DI EV+ QN + + S +F ++ + T+ R+ ++K K + K+MCY++L +F + +Y Sbjct: 10 MLEEENDRLTESLSGKVKALKSLSIDIGHEVRTQNKLLQEMLSIDIGHEVRTQNKLLQEMDDDFDTSGSLLSATMGRLSALTK--KGHHKVMCYMILFCFFVFLVAWY 115
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Medaka
Match: BET1L (Bet1 golgi vesicular membrane trafficking protein like [Source:NCBI gene;Acc:101161130]) HSP 1 Score: 77.411 bits (189), Expect = 2.434e-19 Identity = 32/96 (33.33%), Postives = 59/96 (61.46%), Query Frame = 1 Query: 40 QSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPL 327 +L+ +N +E L+TK++ L+S A DI EV QN ++DG+ S S G + ++ R + ++ + NR+++CY+ LG+ +FF+ YY+ S + Sbjct: 9 DDMLDAKNKRLAENLATKVSRLKSLAYDIDREVDDQNDYLDGMDSNMMSATGLLTGSVKRFSTMVRSGRDNRRLLCYVSLGLVLIFFMLYYLVSRI 104
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Medaka
Match: bet1 (Bet1 golgi vesicular membrane trafficking protein [Source:NCBI gene;Acc:101158079]) HSP 1 Score: 71.633 bits (174), Expect = 5.619e-17 Identity = 35/90 (38.89%), Postives = 56/90 (62.22%), Query Frame = 1 Query: 43 SLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYY 312 S+ E END E L K++ L+S DI +EVK+QN ++ + S+F ST G +G T+ RV +S+ S K++CY++L +FF+ Y+ Sbjct: 20 SVYEEENDHLQEGLRAKVSALKSLTIDIGTEVKYQNKMLEDMDSDFDSTGGLLGATIGRVKQLSRG--SQTKLLCYMLLFCLFVFFVLYW 107
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Planmine SMEST
Match: SMESG000033511.1 (SMESG000033511.1) HSP 1 Score: 211.846 bits (538), Expect = 1.353e-72 Identity = 103/103 (100.00%), Postives = 103/103 (100.00%), Query Frame = 1 Query: 34 MNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPLFGSTK 342 MNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPLFGSTK Sbjct: 1 MNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNSFIDGLQSEFSSTQGFMGTTLNRVFGISKNQKSNRKIMCYIVLGMAGLFFLFYYIFSPLFGSTK 103 The following BLAST results are available for this feature:
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 4
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 3
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 2
BLAST of t-SNARE coiled-coil homology domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30010078 ID=SMED30010078|Name=t-SNARE coiled-coil homology domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=363bpback to top protein sequence of SMED30010078-orf-1 >SMED30010078-orf-1 ID=SMED30010078-orf-1|Name=SMED30010078-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=115bp NLYKSYMSFRNMNQSLLERENDEQSERLSTKINMLRSFATDIHSEVKHQNback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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