TTF-type domain-containing protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30010074 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of TTF-type domain-containing protein vs. Ensembl Human
Match: ZMYM5 (zinc finger MYM-type containing 5 [Source:HGNC Symbol;Acc:HGNC:13029]) HSP 1 Score: 69.3218 bits (168), Expect = 1.069e-11 Identity = 35/109 (32.11%), Postives = 59/109 (54.13%), Query Frame = 3 Query: 1029 DPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLAN-SGSRNWKKLQERINCHQESTKH 1352 DPGTWP + + + L++ P Q+ +P+D R F Y E R WL+YS +KD+ +C C++FG + ++ L N +G ++W+ L ++ H+ES H Sbjct: 521 DPGTWPRILNIKQRDTLVENVPPQVRNFNFPKDNTGRKFSETYYTRILPNGEKTTRSWLLYSTSKDSVFCLYCKLFG-EGKNQLKNENGCKDWQHLSHILSKHEESEMH 628
BLAST of TTF-type domain-containing protein vs. Ensembl Zebrafish
Match: CR762475.1 (pep chromosome:GRCz11:4:55494751:55498830:1 gene:ENSDARG00000098243.2 transcript:ENSDART00000172605.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR762475.1) HSP 1 Score: 51.2174 bits (121), Expect = 3.528e-6 Identity = 40/169 (23.67%), Postives = 67/169 (39.64%), Query Frame = 3 Query: 921 FKRANIQKENLETQPAKIEMNLSTPNSNLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDER--------NRCFPALSYFSKNSKNESIRRYW------LVYSANKDAAYCFPCRIF----GYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQW 1373 F A+I +EN+ET+ E+ L N E+I ++ + P ++ +R C P ++ F KN++ S +R W L YS DA YCF CRIF + ++++ G W+ ++ H + H M +W Sbjct: 111 FGSASIDQENVETEATAGELPLEESGKESQHRSAAN-----KEDIFAKLMVLSCPTDPAHMQTFNIDLSDRYVEMCEKVGPCQPVMT-FPKNAEGRSFQRSWYTDRPWLEYSPKNDAIYCFSCRIFLREEKFKNKTAWKTLGINTWRSATGKMKEHASTEAHMMSMVRW 273
BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Match: Zmym5 (zinc finger, MYM-type 5 [Source:MGI Symbol;Acc:MGI:3041170]) HSP 1 Score: 70.0922 bits (170), Expect = 4.307e-12 Identity = 34/108 (31.48%), Postives = 53/108 (49.07%), Query Frame = 3 Query: 1029 DPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKH 1352 DPG+WP + + + L+K P Q+ +P+D + F Y E R WL+YSA+KD+ +C CR+FG +G ++W L ++ H ES H Sbjct: 486 DPGSWPRILNMKQREFLVKNNPPQIRNFNFPKDSAGKKFSETYYTRILPNGEKGTRPWLLYSASKDSVFCLYCRLFGEGKNQLRNENGCKDWHHLSHLLSKHDESEMH 593
BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Match: Zmym5 (zinc finger, MYM-type 5 [Source:MGI Symbol;Acc:MGI:3041170]) HSP 1 Score: 70.0922 bits (170), Expect = 4.307e-12 Identity = 34/108 (31.48%), Postives = 53/108 (49.07%), Query Frame = 3 Query: 1029 DPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKH 1352 DPG+WP + + + L+K P Q+ +P+D + F Y E R WL+YSA+KD+ +C CR+FG +G ++W L ++ H ES H Sbjct: 486 DPGSWPRILNMKQREFLVKNNPPQIRNFNFPKDSAGKKFSETYYTRILPNGEKGTRPWLLYSASKDSVFCLYCRLFGEGKNQLRNENGCKDWHHLSHLLSKHDESEMH 593
BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Match: Zmym5 (zinc finger, MYM-type 5 [Source:MGI Symbol;Acc:MGI:3041170]) HSP 1 Score: 70.0922 bits (170), Expect = 4.307e-12 Identity = 34/108 (31.48%), Postives = 53/108 (49.07%), Query Frame = 3 Query: 1029 DPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKH 1352 DPG+WP + + + L+K P Q+ +P+D + F Y E R WL+YSA+KD+ +C CR+FG +G ++W L ++ H ES H Sbjct: 486 DPGSWPRILNMKQREFLVKNNPPQIRNFNFPKDSAGKKFSETYYTRILPNGEKGTRPWLLYSASKDSVFCLYCRLFGEGKNQLRNENGCKDWHHLSHLLSKHDESEMH 593
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Match: sp|A6QPH9|ZMYM5_BOVIN (Zinc finger MYM-type protein 5 OS=Bos taurus OX=9913 GN=ZMYM5 PE=2 SV=2) HSP 1 Score: 73.559 bits (179), Expect = 2.412e-12 Identity = 37/118 (31.36%), Postives = 64/118 (54.24%), Query Frame = 3 Query: 1002 NLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLAN-SGSRNWKKLQERINCHQESTKH 1352 ++I + DPGTWP + + + L++ P Q+ +P+D R F Y + E R WL+YS +KD+ +C C++FG + ++ L N +G R+W+ L ++ H+ES H Sbjct: 512 SIIPAVLSADPGTWPRILSIKQRDTLVENDPPQVRNFNFPKDSTGRKFSETYYTRILANGEKTTRSWLLYSTSKDSVFCLYCKLFG-EGKNQLKNENGCRDWQHLSHILSKHEESEMH 628
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4R3D6|ZMYM5_MACFA (Zinc finger MYM-type protein 5 OS=Macaca fascicularis OX=9541 GN=ZMYM5 PE=2 SV=3) HSP 1 Score: 70.8626 bits (172), Expect = 1.401e-11 Identity = 36/109 (33.03%), Postives = 59/109 (54.13%), Query Frame = 3 Query: 1029 DPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLAN-SGSRNWKKLQERINCHQESTKH 1352 DPGTWP + + + L++ P Q+ +P+D R F Y E R WL+YS +KD+ +C CR+FG + ++ L N +G ++W+ L ++ H+ES H Sbjct: 518 DPGTWPRILNIKQRDTLVENVPPQVRNFNFPKDNTGRKFSETYYTRILPNGEKTTRSWLLYSTSKDSVFCLYCRLFG-EGKNQLKNENGCKDWQHLSHILSKHEESEMH 625
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q3U2E2|ZMYM5_MOUSE (Zinc finger MYM-type protein 5 OS=Mus musculus OX=10090 GN=Zmym5 PE=2 SV=2) HSP 1 Score: 70.0922 bits (170), Expect = 3.013e-11 Identity = 34/108 (31.48%), Postives = 53/108 (49.07%), Query Frame = 3 Query: 1029 DPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKH 1352 DPG+WP + + + L+K P Q+ +P+D + F Y E R WL+YSA+KD+ +C CR+FG +G ++W L ++ H ES H Sbjct: 486 DPGSWPRILNMKQREFLVKNNPPQIRNFNFPKDSAGKKFSETYYTRILPNGEKGTRPWLLYSASKDSVFCLYCRLFGEGKNQLRNENGCKDWHHLSHLLSKHDESEMH 593
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9UJ78|ZMYM5_HUMAN (Zinc finger MYM-type protein 5 OS=Homo sapiens OX=9606 GN=ZMYM5 PE=1 SV=4) HSP 1 Score: 69.3218 bits (168), Expect = 5.136e-11 Identity = 35/109 (32.11%), Postives = 59/109 (54.13%), Query Frame = 3 Query: 1029 DPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLAN-SGSRNWKKLQERINCHQESTKH 1352 DPGTWP + + + L++ P Q+ +P+D R F Y E R WL+YS +KD+ +C C++FG + ++ L N +G ++W+ L ++ H+ES H Sbjct: 521 DPGTWPRILNIKQRDTLVENVPPQVRNFNFPKDNTGRKFSETYYTRILPNGEKTTRSWLLYSTSKDSVFCLYCKLFG-EGKNQLKNENGCKDWQHLSHILSKHEESEMH 628
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: H3AWY1 (TTF-type domain-containing protein OS=Latimeria chalumnae OX=7897 PE=4 SV=1) HSP 1 Score: 105.916 bits (263), Expect = 4.145e-20 Identity = 57/180 (31.67%), Postives = 94/180 (52.22%), Query Frame = 3 Query: 1005 LIQEMDD-----NDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYD-SQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQFPLDSDNSKCGLSLTHEEALKLAGQLKHFSSTTDYKIYLLAKQLETELL 1526 +IQ++D +DPGTWP I ++K K++ GP Q++ ++P DE+ R F A Y K E+I R WLVYS KDA YCF C++F + S S L+ G R+W+ L + + H+ S H W + KCG ++ +E +++++ + I ++ E +L+ Sbjct: 84 VIQDVDQSSINLHDPGTWPSVIDSKLKSKIVDYGPYQVKDIKFPEDEKERHFTASYYLRKLPNGETISRNWLVYSQTKDAVYCFCCKLFPHSTSVSQLSTDGFRSWQDLSQTLKIHENSNSHMKNAMSWDDLGV---RLKCGQTIDTKEQELYQERVRYWHGIIERLIAIIQHLAERKLV 260
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: F0VJK6 (TTF-type domain-containing protein OS=Neospora caninum (strain Liverpool) OX=572307 GN=BN1204_036990 PE=4 SV=1) HSP 1 Score: 104.76 bits (260), Expect = 9.213e-20 Identity = 52/130 (40.00%), Postives = 73/130 (56.15%), Query Frame = 3 Query: 984 LSTPNSNLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQW 1373 L P+++ + D D WP +I E++ +L+KKGPVQL YPRD R F Y+ E + R WLVYS +DA YCF C++F S+ S+ +G R WK + E + H+ S H+SCM QW Sbjct: 543 LCAPSTSHEDDEDLGDLALWPAQITEELRWRLVKKGPVQLVDFPYPRDATQRRFGRQHYWRTLPSGEKLWRSWLVYSRTRDAVYCFCCKLFSQLSK-SVVTTGFRRWKGIAEVLRSHEHSRDHRSCMLQW 671
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: A0A4C1ZBF9 (Zinc finger MYM-type protein 5 OS=Eumeta variegata OX=151549 GN=ZMYM5 PE=4 SV=1) HSP 1 Score: 102.449 bits (254), Expect = 1.215e-19 Identity = 48/159 (30.19%), Postives = 84/159 (52.83%), Query Frame = 3 Query: 906 KSLRSFKRANIQKENLETQPAKIEMNLSTPNSNLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQF 1382 KS S + + + E++P +++ NL + NDPG WP I + +++ +GP+++++ +P ++ R F Y E + R W++YS KDA YCFPCR+FG ++ S ++ G +WK L + + H+ S +HK CM +W Sbjct: 24 KSRSSVPPSTLSSQEHESEPESTSTSMTAGMENLNPQ---NDPGLWPITITDVDRTEIVLRGPIRIKVELFPVNDNGRRFSEYHYNKILVNGEKLDRRWIIYSQTKDAVYCFPCRMFGLENTKSGSSEGVCDWKHLGDYLKSHESSRQHKDCMLKWIHL 179
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: A0A2A9MJP6 (TTF-type domain-containing protein OS=Besnoitia besnoiti OX=94643 GN=BESB_052630 PE=4 SV=1) HSP 1 Score: 104.375 bits (259), Expect = 1.439e-19 Identity = 51/130 (39.23%), Postives = 75/130 (57.69%), Query Frame = 3 Query: 987 STPNSNLIQEMDD-NDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQW 1373 + P+ + +E D+ D WP +I E++ +L+K+GPVQL YPRD R F Y+ E + R WLVYS +DA YCF C++F S+ S+ +G R WK + E + H++S H+SCM QW Sbjct: 556 AAPSPSCTEEEDEFADLALWPAQISEELRWRLVKRGPVQLVHYPYPRDNTQRRFGRQHYWRTLPSGEKLWRSWLVYSRTRDAVYCFCCKLFSQLSK-SVVTTGFRRWKGIAEVLRSHEQSRDHRSCMLQW 684
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: A0A4C1VF80 (Zinc finger MYM-type protein 5 OS=Eumeta variegata OX=151549 GN=ZMYM5 PE=4 SV=1) HSP 1 Score: 101.293 bits (251), Expect = 5.404e-19 Identity = 47/148 (31.76%), Postives = 75/148 (50.68%), Query Frame = 3 Query: 939 QKENLETQPAKIEMNLSTPNSNLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQF 1382 Q+ E +P M N N NDPG WP I + +++ +GP+++++ +P ++ R F Y E + R W++YS KDA YCFPCRIFG ++ ++ G +WK L + + H+ S +HK CM +W Sbjct: 58 QEHESEPEPTFTSMTAGMENLN-----PQNDPGLWPITITDVDRTEIVLRGPIRIKVELFPVNDNGRRFSEYHYNKILVNGEKLDRRWMIYSQTKDAVYCFPCRIFGLENTKIGSSEGVCDWKHLGDYLKSHESSRQHKDCMLKWIHL 200
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000036272.1 (pep primary_assembly:Astyanax_mexicanus-2.0:20:11935414:11938921:1 gene:ENSAMXG00000041670.1 transcript:ENSAMXT00000036272.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 93.5893 bits (231), Expect = 1.573e-19 Identity = 44/135 (32.59%), Postives = 71/135 (52.59%), Query Frame = 3 Query: 975 EMNLSTPNSNL-IQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELT-EYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQW 1373 E+N+ +PN + + DP WP I +++L++ GP+ + T ++PR R F A + E I+R W+VYSA +A +CFPC++FG S + L +G +W + + H+ S H CM QW Sbjct: 75 EVNVPSPNDDGEVNVPSSKDPALWPVHISDSDRVELVRGGPLMVPDTFQFPRGPDGRAFHAGLQYKSLPNKEKIKRSWMVYSAQSNAVFCFPCKLFGTKS-TRLTKTGYSDWSNINICLRSHEGSPDHTKCMLQW 208
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000037907.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002089.1:152797:155023:-1 gene:ENSAMXG00000037599.1 transcript:ENSAMXT00000037907.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 84.7297 bits (208), Expect = 8.465e-17 Identity = 38/116 (32.76%), Postives = 70/116 (60.34%), Query Frame = 3 Query: 1026 NDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPR--DERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCME 1367 +DP WPE + + + +++K+GPVQ++ ++P+ D+ R F +Y K + E I WLVYS + D+ +CF C +F +S+ +L++SG R+W + + H++S H + M+ Sbjct: 12 DDPALWPETLTDQQRCEIIKRGPVQIKEFDFPQNNDKIPRQFTVDNYHMKMNNGEKINWNWLVYSLSSDSVFCFCCTVFERESKFALSSSGFRSWINIHSHLRDHEKSKIHCANMQ 127
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000044961.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000032.1:419978:423709:1 gene:ENSAMXG00000036481.1 transcript:ENSAMXT00000044961.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 77.7962 bits (190), Expect = 9.899e-15 Identity = 40/136 (29.41%), Postives = 67/136 (49.26%), Query Frame = 3 Query: 981 NLSTPNSNLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERN--RCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQF 1382 ++ST + D+DP WP+ + + ++++KG VQ+ ++P++ N R F +Y E I R WLVYS + D+ +CFPC +FG ++L+ WK L + H+ S H M W + Sbjct: 51 DISTAQGTTSTFIIDDDPAQWPKVLTDSERCQIVRKGTVQITDIQFPQNSENPPRRFTKENYRRTMKNGEKILRSWLVYSMSTDSVFCFPCTVFG-KRDNALSKLWFHKWKNLTYHLKEHEYSKGHCDNMRNWHEL 185
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000025204.2 (pep primary_assembly:Astyanax_mexicanus-2.0:12:7364240:7371214:-1 gene:ENSAMXG00000024490.2 transcript:ENSAMXT00000025204.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 73.559 bits (179), Expect = 2.748e-13 Identity = 36/107 (33.64%), Postives = 56/107 (52.34%), Query Frame = 3 Query: 1068 KIKLLKKGPVQLELTEYPRDERN--RCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQF 1382 + ++++KGPVQ+ E+P++ N R F +Y E I R WLVYS + D+ +CFPC + G ++L+N G WK L + H+ S H M W + Sbjct: 30 RCQIVRKGPVQITDIEFPQNSENPPRRFTKENYRRTMKNGEKILRSWLVYSMSTDSVFCFPCTVLG-KRDNALSNCGFHKWKNLTYHLKEHEYSKGHCDNMRNWHEL 135
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000033195.1 (pep primary_assembly:Astyanax_mexicanus-2.0:16:11277158:11279506:-1 gene:ENSAMXG00000030798.1 transcript:ENSAMXT00000033195.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 70.8626 bits (172), Expect = 1.722e-12 Identity = 39/139 (28.06%), Postives = 74/139 (53.24%), Query Frame = 3 Query: 993 PNSNLIQEMDDNDPGTWPEEIPGEMKIKLL-KKGPVQLELTEY-PRDERNRCFP-ALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYD----SQSSL-ANSGSR----NWKKLQERINCHQESTKHKSCMEQW 1373 P +++ DPG WP+++ + + L+ + +++LT+ P+D+ + FP L Y + E IRR WL++S + A +C PC +F ++ S+S+L + G + W+K+ + H++ T HK C +W Sbjct: 20 PGEGNTEQLLSEDPGLWPDKLTAQQRETLVCRLASERVDLTKVAPKDKEGKAFPDYLQYVKSANMREKIRRDWLIHSDSAKALFCIPCLLFSHEQTRPSKSALNSKDGLKLSDIKWQKMYRKFPEHEKHTPHKQCYVKW 158
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000028133.1 (zinc finger MYM-type protein 1-like [Source:NCBI gene;Acc:111948955]) HSP 1 Score: 77.0258 bits (188), Expect = 2.218e-14 Identity = 36/121 (29.75%), Postives = 65/121 (53.72%), Query Frame = 3 Query: 1026 NDPGTWPEEIPGEMKIKLLKKGPVQLEL-TEYPRDERNRCFPALSYFSKN-SKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQF 1382 DP WP + ++++L+++GP + +PR++ + YF K E I R WL+YS K++ +CF C++F + +L SG+ NWK + H++S +H +CM+ W + Sbjct: 123 TDPAKWPSPLTDRIRMELVRRGPSSIPPDFVFPRNDSDGRSCHHHYFRKTLVSGEKIARTWLMYSKVKNSLFCFCCKLFS-NKNINLTTSGTANWKHASTYLTAHEKSPEHLNCMKAWKEL 242
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000042294.1 (zinc finger MYM-type protein 1-like [Source:NCBI gene;Acc:110016639]) HSP 1 Score: 77.0258 bits (188), Expect = 2.218e-14 Identity = 36/121 (29.75%), Postives = 65/121 (53.72%), Query Frame = 3 Query: 1026 NDPGTWPEEIPGEMKIKLLKKGPVQLEL-TEYPRDERNRCFPALSYFSKN-SKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQF 1382 DP WP + ++++L+++GP + +PR++ + YF K E I R WL+YS K++ +CF C++F + +L SG+ NWK + H++S +H +CM+ W + Sbjct: 123 TDPAKWPSPLTDRIRMELVRRGPSSIPPDFVFPRNDSDGRSCHHHYFRKTLVSGEKIARTWLMYSKVKNSLFCFCCKLFS-NKNINLTTSGTANWKHASTYLTAHEKSPEHLNCMKAWKEL 242
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000045044.1 (zinc finger MYM-type protein 1-like [Source:NCBI gene;Acc:111948193]) HSP 1 Score: 77.0258 bits (188), Expect = 2.218e-14 Identity = 36/121 (29.75%), Postives = 65/121 (53.72%), Query Frame = 3 Query: 1026 NDPGTWPEEIPGEMKIKLLKKGPVQLEL-TEYPRDERNRCFPALSYFSKN-SKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQF 1382 DP WP + ++++L+++GP + +PR++ + YF K E I R WL+YS K++ +CF C++F + +L SG+ NWK + H++S +H +CM+ W + Sbjct: 123 TDPAKWPSPLTDRIRMELVRRGPSSIPPDFVFPRNDSDGRSCHHHYFRKTLVSGEKIARTWLMYSKVKNSLFCFCCKLFS-NKNINLTTSGTANWKHASTYLTAHEKSPEHLNCMKAWKEL 242
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000027735.1 (pep primary_assembly:ASM223467v1:9:30712608:30715295:1 gene:ENSORLG00000030268.1 transcript:ENSORLT00000027735.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 53.5286 bits (127), Expect = 4.048e-7 Identity = 41/120 (34.17%), Postives = 57/120 (47.50%), Query Frame = 3 Query: 1053 IPGEMKIKLLK-KGPVQLELTEYPR---DERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGY-DSQSSLANS--GSRNWKKLQER---INCHQESTKHKSCMEQWAQF 1382 IPG I + + P Q L +PR +R RCF SK+ WL YS +KD+A+C+ CR FG S S+ S G +NWKK + + H S H + M WA++ Sbjct: 86 IPGLTDISQSRAEHPKQPHLKCFPRTYQGDRRRCF---------SKDWYNAHKWLEYSQSKDSAFCYACRHFGLPASGESVLTSEEGFKNWKKATFKDGGLLGHARSEAHTTAMLAWAEY 196
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000076895.1 (SMESG000076895.1) HSP 1 Score: 959.518 bits (2479), Expect = 0.000e+0 Identity = 498/505 (98.61%), Postives = 501/505 (99.21%), Query Frame = 3 Query: 51 MSKRNMEYEDYNDGKRQKIXXXXXXXXXXXXXFFEDNYMTTENNNVCEMFYDISCQNGSNGEEPYTVEPENKINEINLNSNGEIFKTEAVLNLEPTIENIINKKNDNLYEMENFNDCIVNATIISNVELPTMDXXXXXXXXXXXXXQDLKRIITEKDQILNNTAKDIASNNEQVNEAFQDLPAVIQESINKSVDNVPEVTNKEIKAKKTLVEEVKPSYRLRSSIGTLEVSDEEKKDRKRNSTRVKMAPLKEKKVSINEENISFNDKDGVEIASDLTTQSADVTRRKSLRSFKRANIQKENLETQPAKIEMNLSTPNSNLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQFPLDSDNSKCGLSLTHEEALKLAGQLKHFSSTTDYKIYLLAKQLETELLNFVRDEGEETRQK 1565 MSKRNMEYEDYNDGKRQKINENNELNNSSPLLFFEDNYMTTENNNVCEMFYDISCQNGSNGEEPYTVEPENKINEINLNSNGEIFKTEAVLNLEPTIENIINKKNDNLYEMENFNDCIVNATIISNVELPT+DVIVNENFENINENQDLKRIITEKD+ILNNTAKDIASNNEQVNEAFQDLPAVI ESINKSVDNVPE+ NKEIKAKKTLVEEVKPSYRLRSSIGTLEVSDEEKKDRKRNSTRVKMAPLK KKVSINEENISFNDKDGVEIA DLTTQSADVTRRKSLRSFKRANIQKENLETQPAKIEMNLSTPNSNLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQFPLDSDNSKCGLSLTHEEALKLAGQLKHFSSTTDYKIYLLAKQLETELLNFVRDEGEETRQK Sbjct: 1 MSKRNMEYEDYNDGKRQKINENNELNNSSPLLFFEDNYMTTENNNVCEMFYDISCQNGSNGEEPYTVEPENKINEINLNSNGEIFKTEAVLNLEPTIENIINKKNDNLYEMENFNDCIVNATIISNVELPTIDVIVNENFENINENQDLKRIITEKDKILNNTAKDIASNNEQVNEAFQDLPAVIHESINKSVDNVPELNNKEIKAKKTLVEEVKPSYRLRSSIGTLEVSDEEKKDRKRNSTRVKMAPLKMKKVSINEENISFNDKDGVEIARDLTTQSADVTRRKSLRSFKRANIQKENLETQPAKIEMNLSTPNSNLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQFPLDSDNSKCGLSLTHEEALKLAGQLKHFSSTTDYKIYLLAKQLETELLNFVRDEGEETRQK 505
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000026738.1 (SMESG000026738.1) HSP 1 Score: 87.4261 bits (215), Expect = 8.276e-18 Identity = 43/146 (29.45%), Postives = 77/146 (52.74%), Query Frame = 3 Query: 981 NLSTPNSNLIQEMDD---------NDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQFPLD 1391 +++ PN + I E+++ NDP WP + ++ L++KGPVQ + YP +E R F + ++ K E R WL+YS DA +CF C++FG + L N G ++W+ + + ++ H+++T H W + L+ Sbjct: 82 DIAAPNIDDITEINEEYFDMCIELNDPACWPLALTDKVLDILIEKGPVQNIQSTYPLNEFGRSFSKVYFYRKLPNGEKFNREWLIYSPKNDATFCFCCKLFG-KQEIKLVNEGFKDWQHISDNLSRHEKTTLHIENCTCWKKLELN 226
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000061124.1 (SMESG000061124.1) HSP 1 Score: 85.1149 bits (209), Expect = 5.924e-17 Identity = 41/133 (30.83%), Postives = 72/133 (54.14%), Query Frame = 3 Query: 981 NLSTPNSNLIQEMDD---------NDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKH 1352 +++ PN + I E+++ NDP WP + ++ L++KGPVQ + YP +E R F + ++ K E R WL+YS DA +CF C++FG + L N G +W+ + + ++ H+++T H Sbjct: 82 DIAAPNIDDITEINEEYFDMCIELNDPACWPLALTDKVLDILIEKGPVQNIQSTYPLNEFGRSFSKVYFYRKLPNGEKFNREWLIYSPKNDATFCFCCKLFG-KQEIKLVNEGFNDWQHISDNLSRHEKTTLH 213
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000061124.1 (SMESG000061124.1) HSP 1 Score: 85.1149 bits (209), Expect = 6.604e-17 Identity = 41/133 (30.83%), Postives = 72/133 (54.14%), Query Frame = 3 Query: 981 NLSTPNSNLIQEMDD---------NDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKH 1352 +++ PN + I E+++ NDP WP + ++ L++KGPVQ + YP +E R F + ++ K E R WL+YS DA +CF C++FG + L N G +W+ + + ++ H+++T H Sbjct: 82 DIAAPNIDDITEINEEYFDMCIELNDPACWPLALTDKVLDILIEKGPVQNIQSTYPLNEFGRSFSKVYFYRKLPNGEKFNREWLIYSPKNDATFCFCCKLFG-KQEIKLVNEGFNDWQHISDNLSRHEKTTLH 213
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000061124.1 (SMESG000061124.1) HSP 1 Score: 85.1149 bits (209), Expect = 6.806e-17 Identity = 41/133 (30.83%), Postives = 72/133 (54.14%), Query Frame = 3 Query: 981 NLSTPNSNLIQEMDD---------NDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKH 1352 +++ PN + I E+++ NDP WP + ++ L++KGPVQ + YP +E R F + ++ K E R WL+YS DA +CF C++FG + L N G +W+ + + ++ H+++T H Sbjct: 82 DIAAPNIDDITEINEEYFDMCIELNDPACWPLALTDKVLDILIEKGPVQNIQSTYPLNEFGRSFSKVYFYRKLPNGEKFNREWLIYSPKNDATFCFCCKLFG-KQEIKLVNEGFNDWQHISDNLSRHEKTTLH 213 The following BLAST results are available for this feature:
BLAST of TTF-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 1
BLAST of TTF-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of TTF-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of TTF-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of TTF-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 0
BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 3
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 4
BLAST of TTF-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of TTF-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of TTF-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of TTF-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 4
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30010074 ID=SMED30010074|Name=TTF-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1668bpback to top protein sequence of SMED30010074-orf-1 >SMED30010074-orf-1 ID=SMED30010074-orf-1|Name=SMED30010074-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=506bp MSKRNMEYEDYNDGKRQKINENNELNNSSPLLFFEDNYMTTENNNVCEMFback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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