TTF-type domain-containing protein

Overview
NameTTF-type domain-containing protein
Smed IDSMED30010074
Length (bp)1668
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of TTF-type domain-containing protein (SMED30010074) t-SNE clustered cells

Violin plots show distribution of expression levels for TTF-type domain-containing protein (SMED30010074) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of TTF-type domain-containing protein (SMED30010074) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for TTF-type domain-containing protein (SMED30010074) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30010074

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30010074h1SMcG0008288 SmedASXL_010952SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30010074h1SMcG0008288 dd_Smed_v4_5933_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30010074h1SMcG0008288 dd_Smed_v4_5933_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30010074h1SMcG0008288 dd_Smed_v4_5933_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30010074h1SMcG0008288 dd_Smed_v4_5933_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30010074h1SMcG0008288 Contig42801newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30010074h1SMcG0008288 Contig42801uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
neoblastSMED30010074h1SMcG0008288 SMED_13911_V2_2GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012
whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30010074h1SMcG0008288 SMED_13911_V2_2GPL14150PMID:22385657
Wagner et al., 2012
whole organism asexual adult cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
BLAST of TTF-type domain-containing protein vs. Ensembl Human
Match: ZMYM5 (zinc finger MYM-type containing 5 [Source:HGNC Symbol;Acc:HGNC:13029])

HSP 1 Score: 69.3218 bits (168), Expect = 1.069e-11
Identity = 35/109 (32.11%), Postives = 59/109 (54.13%), Query Frame = 3
Query: 1029 DPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLAN-SGSRNWKKLQERINCHQESTKH 1352
            DPGTWP  +  + +  L++  P Q+    +P+D   R F    Y       E   R WL+YS +KD+ +C  C++FG + ++ L N +G ++W+ L   ++ H+ES  H
Sbjct:  521 DPGTWPRILNIKQRDTLVENVPPQVRNFNFPKDNTGRKFSETYYTRILPNGEKTTRSWLLYSTSKDSVFCLYCKLFG-EGKNQLKNENGCKDWQHLSHILSKHEESEMH 628          
BLAST of TTF-type domain-containing protein vs. Ensembl Zebrafish
Match: CR762475.1 (pep chromosome:GRCz11:4:55494751:55498830:1 gene:ENSDARG00000098243.2 transcript:ENSDART00000172605.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR762475.1)

HSP 1 Score: 51.2174 bits (121), Expect = 3.528e-6
Identity = 40/169 (23.67%), Postives = 67/169 (39.64%), Query Frame = 3
Query:  921 FKRANIQKENLETQPAKIEMNLSTPNSNLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDER--------NRCFPALSYFSKNSKNESIRRYW------LVYSANKDAAYCFPCRIF----GYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQW 1373
            F  A+I +EN+ET+    E+ L             N      E+I  ++ +      P  ++       +R          C P ++ F KN++  S +R W      L YS   DA YCF CRIF     + ++++    G   W+    ++  H  +  H   M +W
Sbjct:  111 FGSASIDQENVETEATAGELPLEESGKESQHRSAAN-----KEDIFAKLMVLSCPTDPAHMQTFNIDLSDRYVEMCEKVGPCQPVMT-FPKNAEGRSFQRSWYTDRPWLEYSPKNDAIYCFSCRIFLREEKFKNKTAWKTLGINTWRSATGKMKEHASTEAHMMSMVRW 273          
BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Match: Zmym5 (zinc finger, MYM-type 5 [Source:MGI Symbol;Acc:MGI:3041170])

HSP 1 Score: 70.0922 bits (170), Expect = 4.307e-12
Identity = 34/108 (31.48%), Postives = 53/108 (49.07%), Query Frame = 3
Query: 1029 DPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKH 1352
            DPG+WP  +  + +  L+K  P Q+    +P+D   + F    Y       E   R WL+YSA+KD+ +C  CR+FG         +G ++W  L   ++ H ES  H
Sbjct:  486 DPGSWPRILNMKQREFLVKNNPPQIRNFNFPKDSAGKKFSETYYTRILPNGEKGTRPWLLYSASKDSVFCLYCRLFGEGKNQLRNENGCKDWHHLSHLLSKHDESEMH 593          
BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Match: Zmym5 (zinc finger, MYM-type 5 [Source:MGI Symbol;Acc:MGI:3041170])

HSP 1 Score: 70.0922 bits (170), Expect = 4.307e-12
Identity = 34/108 (31.48%), Postives = 53/108 (49.07%), Query Frame = 3
Query: 1029 DPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKH 1352
            DPG+WP  +  + +  L+K  P Q+    +P+D   + F    Y       E   R WL+YSA+KD+ +C  CR+FG         +G ++W  L   ++ H ES  H
Sbjct:  486 DPGSWPRILNMKQREFLVKNNPPQIRNFNFPKDSAGKKFSETYYTRILPNGEKGTRPWLLYSASKDSVFCLYCRLFGEGKNQLRNENGCKDWHHLSHLLSKHDESEMH 593          
BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Match: Zmym5 (zinc finger, MYM-type 5 [Source:MGI Symbol;Acc:MGI:3041170])

HSP 1 Score: 70.0922 bits (170), Expect = 4.307e-12
Identity = 34/108 (31.48%), Postives = 53/108 (49.07%), Query Frame = 3
Query: 1029 DPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKH 1352
            DPG+WP  +  + +  L+K  P Q+    +P+D   + F    Y       E   R WL+YSA+KD+ +C  CR+FG         +G ++W  L   ++ H ES  H
Sbjct:  486 DPGSWPRILNMKQREFLVKNNPPQIRNFNFPKDSAGKKFSETYYTRILPNGEKGTRPWLLYSASKDSVFCLYCRLFGEGKNQLRNENGCKDWHHLSHLLSKHDESEMH 593          
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Match: sp|A6QPH9|ZMYM5_BOVIN (Zinc finger MYM-type protein 5 OS=Bos taurus OX=9913 GN=ZMYM5 PE=2 SV=2)

HSP 1 Score: 73.559 bits (179), Expect = 2.412e-12
Identity = 37/118 (31.36%), Postives = 64/118 (54.24%), Query Frame = 3
Query: 1002 NLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLAN-SGSRNWKKLQERINCHQESTKH 1352
            ++I  +   DPGTWP  +  + +  L++  P Q+    +P+D   R F    Y    +  E   R WL+YS +KD+ +C  C++FG + ++ L N +G R+W+ L   ++ H+ES  H
Sbjct:  512 SIIPAVLSADPGTWPRILSIKQRDTLVENDPPQVRNFNFPKDSTGRKFSETYYTRILANGEKTTRSWLLYSTSKDSVFCLYCKLFG-EGKNQLKNENGCRDWQHLSHILSKHEESEMH 628          
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4R3D6|ZMYM5_MACFA (Zinc finger MYM-type protein 5 OS=Macaca fascicularis OX=9541 GN=ZMYM5 PE=2 SV=3)

HSP 1 Score: 70.8626 bits (172), Expect = 1.401e-11
Identity = 36/109 (33.03%), Postives = 59/109 (54.13%), Query Frame = 3
Query: 1029 DPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLAN-SGSRNWKKLQERINCHQESTKH 1352
            DPGTWP  +  + +  L++  P Q+    +P+D   R F    Y       E   R WL+YS +KD+ +C  CR+FG + ++ L N +G ++W+ L   ++ H+ES  H
Sbjct:  518 DPGTWPRILNIKQRDTLVENVPPQVRNFNFPKDNTGRKFSETYYTRILPNGEKTTRSWLLYSTSKDSVFCLYCRLFG-EGKNQLKNENGCKDWQHLSHILSKHEESEMH 625          
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q3U2E2|ZMYM5_MOUSE (Zinc finger MYM-type protein 5 OS=Mus musculus OX=10090 GN=Zmym5 PE=2 SV=2)

HSP 1 Score: 70.0922 bits (170), Expect = 3.013e-11
Identity = 34/108 (31.48%), Postives = 53/108 (49.07%), Query Frame = 3
Query: 1029 DPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKH 1352
            DPG+WP  +  + +  L+K  P Q+    +P+D   + F    Y       E   R WL+YSA+KD+ +C  CR+FG         +G ++W  L   ++ H ES  H
Sbjct:  486 DPGSWPRILNMKQREFLVKNNPPQIRNFNFPKDSAGKKFSETYYTRILPNGEKGTRPWLLYSASKDSVFCLYCRLFGEGKNQLRNENGCKDWHHLSHLLSKHDESEMH 593          
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9UJ78|ZMYM5_HUMAN (Zinc finger MYM-type protein 5 OS=Homo sapiens OX=9606 GN=ZMYM5 PE=1 SV=4)

HSP 1 Score: 69.3218 bits (168), Expect = 5.136e-11
Identity = 35/109 (32.11%), Postives = 59/109 (54.13%), Query Frame = 3
Query: 1029 DPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLAN-SGSRNWKKLQERINCHQESTKH 1352
            DPGTWP  +  + +  L++  P Q+    +P+D   R F    Y       E   R WL+YS +KD+ +C  C++FG + ++ L N +G ++W+ L   ++ H+ES  H
Sbjct:  521 DPGTWPRILNIKQRDTLVENVPPQVRNFNFPKDNTGRKFSETYYTRILPNGEKTTRSWLLYSTSKDSVFCLYCKLFG-EGKNQLKNENGCKDWQHLSHILSKHEESEMH 628          
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: H3AWY1 (TTF-type domain-containing protein OS=Latimeria chalumnae OX=7897 PE=4 SV=1)

HSP 1 Score: 105.916 bits (263), Expect = 4.145e-20
Identity = 57/180 (31.67%), Postives = 94/180 (52.22%), Query Frame = 3
Query: 1005 LIQEMDD-----NDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYD-SQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQFPLDSDNSKCGLSLTHEEALKLAGQLKHFSSTTDYKIYLLAKQLETELL 1526
            +IQ++D      +DPGTWP  I  ++K K++  GP Q++  ++P DE+ R F A  Y  K    E+I R WLVYS  KDA YCF C++F +  S S L+  G R+W+ L + +  H+ S  H      W    +     KCG ++  +E      +++++    +  I ++    E +L+
Sbjct:   84 VIQDVDQSSINLHDPGTWPSVIDSKLKSKIVDYGPYQVKDIKFPEDEKERHFTASYYLRKLPNGETISRNWLVYSQTKDAVYCFCCKLFPHSTSVSQLSTDGFRSWQDLSQTLKIHENSNSHMKNAMSWDDLGV---RLKCGQTIDTKEQELYQERVRYWHGIIERLIAIIQHLAERKLV 260          
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: F0VJK6 (TTF-type domain-containing protein OS=Neospora caninum (strain Liverpool) OX=572307 GN=BN1204_036990 PE=4 SV=1)

HSP 1 Score: 104.76 bits (260), Expect = 9.213e-20
Identity = 52/130 (40.00%), Postives = 73/130 (56.15%), Query Frame = 3
Query:  984 LSTPNSNLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQW 1373
            L  P+++   + D  D   WP +I  E++ +L+KKGPVQL    YPRD   R F    Y+      E + R WLVYS  +DA YCF C++F   S+ S+  +G R WK + E +  H+ S  H+SCM QW
Sbjct:  543 LCAPSTSHEDDEDLGDLALWPAQITEELRWRLVKKGPVQLVDFPYPRDATQRRFGRQHYWRTLPSGEKLWRSWLVYSRTRDAVYCFCCKLFSQLSK-SVVTTGFRRWKGIAEVLRSHEHSRDHRSCMLQW 671          
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: A0A4C1ZBF9 (Zinc finger MYM-type protein 5 OS=Eumeta variegata OX=151549 GN=ZMYM5 PE=4 SV=1)

HSP 1 Score: 102.449 bits (254), Expect = 1.215e-19
Identity = 48/159 (30.19%), Postives = 84/159 (52.83%), Query Frame = 3
Query:  906 KSLRSFKRANIQKENLETQPAKIEMNLSTPNSNLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQF 1382
            KS  S   + +  +  E++P     +++    NL  +   NDPG WP  I    + +++ +GP+++++  +P ++  R F    Y       E + R W++YS  KDA YCFPCR+FG ++  S ++ G  +WK L + +  H+ S +HK CM +W   
Sbjct:   24 KSRSSVPPSTLSSQEHESEPESTSTSMTAGMENLNPQ---NDPGLWPITITDVDRTEIVLRGPIRIKVELFPVNDNGRRFSEYHYNKILVNGEKLDRRWIIYSQTKDAVYCFPCRMFGLENTKSGSSEGVCDWKHLGDYLKSHESSRQHKDCMLKWIHL 179          
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: A0A2A9MJP6 (TTF-type domain-containing protein OS=Besnoitia besnoiti OX=94643 GN=BESB_052630 PE=4 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 1.439e-19
Identity = 51/130 (39.23%), Postives = 75/130 (57.69%), Query Frame = 3
Query:  987 STPNSNLIQEMDD-NDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQW 1373
            + P+ +  +E D+  D   WP +I  E++ +L+K+GPVQL    YPRD   R F    Y+      E + R WLVYS  +DA YCF C++F   S+ S+  +G R WK + E +  H++S  H+SCM QW
Sbjct:  556 AAPSPSCTEEEDEFADLALWPAQISEELRWRLVKRGPVQLVHYPYPRDNTQRRFGRQHYWRTLPSGEKLWRSWLVYSRTRDAVYCFCCKLFSQLSK-SVVTTGFRRWKGIAEVLRSHEQSRDHRSCMLQW 684          
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: A0A4C1VF80 (Zinc finger MYM-type protein 5 OS=Eumeta variegata OX=151549 GN=ZMYM5 PE=4 SV=1)

HSP 1 Score: 101.293 bits (251), Expect = 5.404e-19
Identity = 47/148 (31.76%), Postives = 75/148 (50.68%), Query Frame = 3
Query:  939 QKENLETQPAKIEMNLSTPNSNLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQF 1382
            Q+   E +P    M     N N       NDPG WP  I    + +++ +GP+++++  +P ++  R F    Y       E + R W++YS  KDA YCFPCRIFG ++    ++ G  +WK L + +  H+ S +HK CM +W   
Sbjct:   58 QEHESEPEPTFTSMTAGMENLN-----PQNDPGLWPITITDVDRTEIVLRGPIRIKVELFPVNDNGRRFSEYHYNKILVNGEKLDRRWMIYSQTKDAVYCFPCRIFGLENTKIGSSEGVCDWKHLGDYLKSHESSRQHKDCMLKWIHL 200          
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000036272.1 (pep primary_assembly:Astyanax_mexicanus-2.0:20:11935414:11938921:1 gene:ENSAMXG00000041670.1 transcript:ENSAMXT00000036272.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 93.5893 bits (231), Expect = 1.573e-19
Identity = 44/135 (32.59%), Postives = 71/135 (52.59%), Query Frame = 3
Query:  975 EMNLSTPNSNL-IQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELT-EYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQW 1373
            E+N+ +PN +  +      DP  WP  I    +++L++ GP+ +  T ++PR    R F A   +      E I+R W+VYSA  +A +CFPC++FG  S + L  +G  +W  +   +  H+ S  H  CM QW
Sbjct:   75 EVNVPSPNDDGEVNVPSSKDPALWPVHISDSDRVELVRGGPLMVPDTFQFPRGPDGRAFHAGLQYKSLPNKEKIKRSWMVYSAQSNAVFCFPCKLFGTKS-TRLTKTGYSDWSNINICLRSHEGSPDHTKCMLQW 208          
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000037907.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002089.1:152797:155023:-1 gene:ENSAMXG00000037599.1 transcript:ENSAMXT00000037907.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 84.7297 bits (208), Expect = 8.465e-17
Identity = 38/116 (32.76%), Postives = 70/116 (60.34%), Query Frame = 3
Query: 1026 NDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPR--DERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCME 1367
            +DP  WPE +  + + +++K+GPVQ++  ++P+  D+  R F   +Y  K +  E I   WLVYS + D+ +CF C +F  +S+ +L++SG R+W  +   +  H++S  H + M+
Sbjct:   12 DDPALWPETLTDQQRCEIIKRGPVQIKEFDFPQNNDKIPRQFTVDNYHMKMNNGEKINWNWLVYSLSSDSVFCFCCTVFERESKFALSSSGFRSWINIHSHLRDHEKSKIHCANMQ 127          
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000044961.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000032.1:419978:423709:1 gene:ENSAMXG00000036481.1 transcript:ENSAMXT00000044961.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 77.7962 bits (190), Expect = 9.899e-15
Identity = 40/136 (29.41%), Postives = 67/136 (49.26%), Query Frame = 3
Query:  981 NLSTPNSNLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERN--RCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQF 1382
            ++ST        + D+DP  WP+ +    + ++++KG VQ+   ++P++  N  R F   +Y       E I R WLVYS + D+ +CFPC +FG    ++L+      WK L   +  H+ S  H   M  W + 
Sbjct:   51 DISTAQGTTSTFIIDDDPAQWPKVLTDSERCQIVRKGTVQITDIQFPQNSENPPRRFTKENYRRTMKNGEKILRSWLVYSMSTDSVFCFPCTVFG-KRDNALSKLWFHKWKNLTYHLKEHEYSKGHCDNMRNWHEL 185          
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000025204.2 (pep primary_assembly:Astyanax_mexicanus-2.0:12:7364240:7371214:-1 gene:ENSAMXG00000024490.2 transcript:ENSAMXT00000025204.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 73.559 bits (179), Expect = 2.748e-13
Identity = 36/107 (33.64%), Postives = 56/107 (52.34%), Query Frame = 3
Query: 1068 KIKLLKKGPVQLELTEYPRDERN--RCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQF 1382
            + ++++KGPVQ+   E+P++  N  R F   +Y       E I R WLVYS + D+ +CFPC + G    ++L+N G   WK L   +  H+ S  H   M  W + 
Sbjct:   30 RCQIVRKGPVQITDIEFPQNSENPPRRFTKENYRRTMKNGEKILRSWLVYSMSTDSVFCFPCTVLG-KRDNALSNCGFHKWKNLTYHLKEHEYSKGHCDNMRNWHEL 135          
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000033195.1 (pep primary_assembly:Astyanax_mexicanus-2.0:16:11277158:11279506:-1 gene:ENSAMXG00000030798.1 transcript:ENSAMXT00000033195.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 70.8626 bits (172), Expect = 1.722e-12
Identity = 39/139 (28.06%), Postives = 74/139 (53.24%), Query Frame = 3
Query:  993 PNSNLIQEMDDNDPGTWPEEIPGEMKIKLL-KKGPVQLELTEY-PRDERNRCFP-ALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYD----SQSSL-ANSGSR----NWKKLQERINCHQESTKHKSCMEQW 1373
            P     +++   DPG WP+++  + +  L+ +    +++LT+  P+D+  + FP  L Y    +  E IRR WL++S +  A +C PC +F ++    S+S+L +  G +     W+K+  +   H++ T HK C  +W
Sbjct:   20 PGEGNTEQLLSEDPGLWPDKLTAQQRETLVCRLASERVDLTKVAPKDKEGKAFPDYLQYVKSANMREKIRRDWLIHSDSAKALFCIPCLLFSHEQTRPSKSALNSKDGLKLSDIKWQKMYRKFPEHEKHTPHKQCYVKW 158          
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000028133.1 (zinc finger MYM-type protein 1-like [Source:NCBI gene;Acc:111948955])

HSP 1 Score: 77.0258 bits (188), Expect = 2.218e-14
Identity = 36/121 (29.75%), Postives = 65/121 (53.72%), Query Frame = 3
Query: 1026 NDPGTWPEEIPGEMKIKLLKKGPVQLEL-TEYPRDERNRCFPALSYFSKN-SKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQF 1382
             DP  WP  +   ++++L+++GP  +     +PR++ +       YF K     E I R WL+YS  K++ +CF C++F  +   +L  SG+ NWK     +  H++S +H +CM+ W + 
Sbjct:  123 TDPAKWPSPLTDRIRMELVRRGPSSIPPDFVFPRNDSDGRSCHHHYFRKTLVSGEKIARTWLMYSKVKNSLFCFCCKLFS-NKNINLTTSGTANWKHASTYLTAHEKSPEHLNCMKAWKEL 242          
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000042294.1 (zinc finger MYM-type protein 1-like [Source:NCBI gene;Acc:110016639])

HSP 1 Score: 77.0258 bits (188), Expect = 2.218e-14
Identity = 36/121 (29.75%), Postives = 65/121 (53.72%), Query Frame = 3
Query: 1026 NDPGTWPEEIPGEMKIKLLKKGPVQLEL-TEYPRDERNRCFPALSYFSKN-SKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQF 1382
             DP  WP  +   ++++L+++GP  +     +PR++ +       YF K     E I R WL+YS  K++ +CF C++F  +   +L  SG+ NWK     +  H++S +H +CM+ W + 
Sbjct:  123 TDPAKWPSPLTDRIRMELVRRGPSSIPPDFVFPRNDSDGRSCHHHYFRKTLVSGEKIARTWLMYSKVKNSLFCFCCKLFS-NKNINLTTSGTANWKHASTYLTAHEKSPEHLNCMKAWKEL 242          
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000045044.1 (zinc finger MYM-type protein 1-like [Source:NCBI gene;Acc:111948193])

HSP 1 Score: 77.0258 bits (188), Expect = 2.218e-14
Identity = 36/121 (29.75%), Postives = 65/121 (53.72%), Query Frame = 3
Query: 1026 NDPGTWPEEIPGEMKIKLLKKGPVQLEL-TEYPRDERNRCFPALSYFSKN-SKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQF 1382
             DP  WP  +   ++++L+++GP  +     +PR++ +       YF K     E I R WL+YS  K++ +CF C++F  +   +L  SG+ NWK     +  H++S +H +CM+ W + 
Sbjct:  123 TDPAKWPSPLTDRIRMELVRRGPSSIPPDFVFPRNDSDGRSCHHHYFRKTLVSGEKIARTWLMYSKVKNSLFCFCCKLFS-NKNINLTTSGTANWKHASTYLTAHEKSPEHLNCMKAWKEL 242          
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000027735.1 (pep primary_assembly:ASM223467v1:9:30712608:30715295:1 gene:ENSORLG00000030268.1 transcript:ENSORLT00000027735.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.5286 bits (127), Expect = 4.048e-7
Identity = 41/120 (34.17%), Postives = 57/120 (47.50%), Query Frame = 3
Query: 1053 IPGEMKIKLLK-KGPVQLELTEYPR---DERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGY-DSQSSLANS--GSRNWKKLQER---INCHQESTKHKSCMEQWAQF 1382
            IPG   I   + + P Q  L  +PR    +R RCF         SK+      WL YS +KD+A+C+ CR FG   S  S+  S  G +NWKK   +   +  H  S  H + M  WA++
Sbjct:   86 IPGLTDISQSRAEHPKQPHLKCFPRTYQGDRRRCF---------SKDWYNAHKWLEYSQSKDSAFCYACRHFGLPASGESVLTSEEGFKNWKKATFKDGGLLGHARSEAHTTAMLAWAEY 196          
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000076895.1 (SMESG000076895.1)

HSP 1 Score: 959.518 bits (2479), Expect = 0.000e+0
Identity = 498/505 (98.61%), Postives = 501/505 (99.21%), Query Frame = 3
Query:   51 MSKRNMEYEDYNDGKRQKIXXXXXXXXXXXXXFFEDNYMTTENNNVCEMFYDISCQNGSNGEEPYTVEPENKINEINLNSNGEIFKTEAVLNLEPTIENIINKKNDNLYEMENFNDCIVNATIISNVELPTMDXXXXXXXXXXXXXQDLKRIITEKDQILNNTAKDIASNNEQVNEAFQDLPAVIQESINKSVDNVPEVTNKEIKAKKTLVEEVKPSYRLRSSIGTLEVSDEEKKDRKRNSTRVKMAPLKEKKVSINEENISFNDKDGVEIASDLTTQSADVTRRKSLRSFKRANIQKENLETQPAKIEMNLSTPNSNLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQFPLDSDNSKCGLSLTHEEALKLAGQLKHFSSTTDYKIYLLAKQLETELLNFVRDEGEETRQK 1565
            MSKRNMEYEDYNDGKRQKINENNELNNSSPLLFFEDNYMTTENNNVCEMFYDISCQNGSNGEEPYTVEPENKINEINLNSNGEIFKTEAVLNLEPTIENIINKKNDNLYEMENFNDCIVNATIISNVELPT+DVIVNENFENINENQDLKRIITEKD+ILNNTAKDIASNNEQVNEAFQDLPAVI ESINKSVDNVPE+ NKEIKAKKTLVEEVKPSYRLRSSIGTLEVSDEEKKDRKRNSTRVKMAPLK KKVSINEENISFNDKDGVEIA DLTTQSADVTRRKSLRSFKRANIQKENLETQPAKIEMNLSTPNSNLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQFPLDSDNSKCGLSLTHEEALKLAGQLKHFSSTTDYKIYLLAKQLETELLNFVRDEGEETRQK
Sbjct:    1 MSKRNMEYEDYNDGKRQKINENNELNNSSPLLFFEDNYMTTENNNVCEMFYDISCQNGSNGEEPYTVEPENKINEINLNSNGEIFKTEAVLNLEPTIENIINKKNDNLYEMENFNDCIVNATIISNVELPTIDVIVNENFENINENQDLKRIITEKDKILNNTAKDIASNNEQVNEAFQDLPAVIHESINKSVDNVPELNNKEIKAKKTLVEEVKPSYRLRSSIGTLEVSDEEKKDRKRNSTRVKMAPLKMKKVSINEENISFNDKDGVEIARDLTTQSADVTRRKSLRSFKRANIQKENLETQPAKIEMNLSTPNSNLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQFPLDSDNSKCGLSLTHEEALKLAGQLKHFSSTTDYKIYLLAKQLETELLNFVRDEGEETRQK 505          
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000026738.1 (SMESG000026738.1)

HSP 1 Score: 87.4261 bits (215), Expect = 8.276e-18
Identity = 43/146 (29.45%), Postives = 77/146 (52.74%), Query Frame = 3
Query:  981 NLSTPNSNLIQEMDD---------NDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQFPLD 1391
            +++ PN + I E+++         NDP  WP  +  ++   L++KGPVQ   + YP +E  R F  + ++ K    E   R WL+YS   DA +CF C++FG   +  L N G ++W+ + + ++ H+++T H      W +  L+
Sbjct:   82 DIAAPNIDDITEINEEYFDMCIELNDPACWPLALTDKVLDILIEKGPVQNIQSTYPLNEFGRSFSKVYFYRKLPNGEKFNREWLIYSPKNDATFCFCCKLFG-KQEIKLVNEGFKDWQHISDNLSRHEKTTLHIENCTCWKKLELN 226          
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000061124.1 (SMESG000061124.1)

HSP 1 Score: 85.1149 bits (209), Expect = 5.924e-17
Identity = 41/133 (30.83%), Postives = 72/133 (54.14%), Query Frame = 3
Query:  981 NLSTPNSNLIQEMDD---------NDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKH 1352
            +++ PN + I E+++         NDP  WP  +  ++   L++KGPVQ   + YP +E  R F  + ++ K    E   R WL+YS   DA +CF C++FG   +  L N G  +W+ + + ++ H+++T H
Sbjct:   82 DIAAPNIDDITEINEEYFDMCIELNDPACWPLALTDKVLDILIEKGPVQNIQSTYPLNEFGRSFSKVYFYRKLPNGEKFNREWLIYSPKNDATFCFCCKLFG-KQEIKLVNEGFNDWQHISDNLSRHEKTTLH 213          
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000061124.1 (SMESG000061124.1)

HSP 1 Score: 85.1149 bits (209), Expect = 6.604e-17
Identity = 41/133 (30.83%), Postives = 72/133 (54.14%), Query Frame = 3
Query:  981 NLSTPNSNLIQEMDD---------NDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKH 1352
            +++ PN + I E+++         NDP  WP  +  ++   L++KGPVQ   + YP +E  R F  + ++ K    E   R WL+YS   DA +CF C++FG   +  L N G  +W+ + + ++ H+++T H
Sbjct:   82 DIAAPNIDDITEINEEYFDMCIELNDPACWPLALTDKVLDILIEKGPVQNIQSTYPLNEFGRSFSKVYFYRKLPNGEKFNREWLIYSPKNDATFCFCCKLFG-KQEIKLVNEGFNDWQHISDNLSRHEKTTLH 213          
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000061124.1 (SMESG000061124.1)

HSP 1 Score: 85.1149 bits (209), Expect = 6.806e-17
Identity = 41/133 (30.83%), Postives = 72/133 (54.14%), Query Frame = 3
Query:  981 NLSTPNSNLIQEMDD---------NDPGTWPEEIPGEMKIKLLKKGPVQLELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCRIFGYDSQSSLANSGSRNWKKLQERINCHQESTKH 1352
            +++ PN + I E+++         NDP  WP  +  ++   L++KGPVQ   + YP +E  R F  + ++ K    E   R WL+YS   DA +CF C++FG   +  L N G  +W+ + + ++ H+++T H
Sbjct:   82 DIAAPNIDDITEINEEYFDMCIELNDPACWPLALTDKVLDILIEKGPVQNIQSTYPLNEFGRSFSKVYFYRKLPNGEKFNREWLIYSPKNDATFCFCCKLFG-KQEIKLVNEGFNDWQHISDNLSRHEKTTLH 213          
The following BLAST results are available for this feature:
BLAST of TTF-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ZMYM51.069e-1132.11zinc finger MYM-type containing 5 [Source:HGNC Sym... [more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TTF-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TTF-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CR762475.13.528e-623.67pep chromosome:GRCz11:4:55494751:55498830:1 gene:E... [more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Zmym54.307e-1231.48zinc finger, MYM-type 5 [Source:MGI Symbol;Acc:MGI... [more]
Zmym54.307e-1231.48zinc finger, MYM-type 5 [Source:MGI Symbol;Acc:MGI... [more]
Zmym54.307e-1231.48zinc finger, MYM-type 5 [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|A6QPH9|ZMYM5_BOVIN2.412e-1231.36Zinc finger MYM-type protein 5 OS=Bos taurus OX=99... [more]
sp|Q4R3D6|ZMYM5_MACFA1.401e-1133.03Zinc finger MYM-type protein 5 OS=Macaca fascicula... [more]
sp|Q3U2E2|ZMYM5_MOUSE3.013e-1131.48Zinc finger MYM-type protein 5 OS=Mus musculus OX=... [more]
sp|Q9UJ78|ZMYM5_HUMAN5.136e-1132.11Zinc finger MYM-type protein 5 OS=Homo sapiens OX=... [more]
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BLAST of TTF-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
H3AWY14.145e-2031.67TTF-type domain-containing protein OS=Latimeria ch... [more]
F0VJK69.213e-2040.00TTF-type domain-containing protein OS=Neospora can... [more]
A0A4C1ZBF91.215e-1930.19Zinc finger MYM-type protein 5 OS=Eumeta variegata... [more]
A0A2A9MJP61.439e-1939.23TTF-type domain-containing protein OS=Besnoitia be... [more]
A0A4C1VF805.404e-1931.76Zinc finger MYM-type protein 5 OS=Eumeta variegata... [more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000036272.11.573e-1932.59pep primary_assembly:Astyanax_mexicanus-2.0:20:119... [more]
ENSAMXT00000037907.18.465e-1732.76pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000044961.19.899e-1529.41pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000025204.22.748e-1333.64pep primary_assembly:Astyanax_mexicanus-2.0:12:736... [more]
ENSAMXT00000033195.11.722e-1228.06pep primary_assembly:Astyanax_mexicanus-2.0:16:112... [more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TTF-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TTF-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ENSORLT00000028133.12.218e-1429.75zinc finger MYM-type protein 1-like [Source:NCBI g... [more]
ENSORLT00000042294.12.218e-1429.75zinc finger MYM-type protein 1-like [Source:NCBI g... [more]
ENSORLT00000045044.12.218e-1429.75zinc finger MYM-type protein 1-like [Source:NCBI g... [more]
ENSORLT00000027735.14.048e-734.17pep primary_assembly:ASM223467v1:9:30712608:307152... [more]
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BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000076895.10.000e+098.61SMESG000076895.1[more]
SMESG000026738.18.276e-1829.45SMESG000026738.1[more]
SMESG000061124.15.924e-1730.83SMESG000061124.1[more]
SMESG000061124.16.604e-1730.83SMESG000061124.1[more]
SMESG000061124.16.806e-1730.83SMESG000061124.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30010074 ID=SMED30010074|Name=TTF-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1668bp
GATCTTTGTTTTAATATTGAGATTATAATTTTAATTCTAATTGCTGAAAA
ATGTCTAAGCGAAATATGGAATATGAAGATTATAATGATGGCAAAAGGCA
GAAAATTAATGAAAATAACGAATTGAATAATTCTTCTCCTTTGTTGTTTT
TTGAAGATAATTACATGACAACAGAAAATAATAATGTTTGCGAAATGTTT
TATGATATTTCTTGTCAGAATGGATCTAATGGAGAAGAACCTTATACTGT
AGAACCTGAAAACAAAATCAATGAAATTAATTTAAATTCTAATGGTGAAA
TTTTCAAAACAGAAGCTGTTTTAAATTTAGAACCTACAATAGAAAATATA
ATAAACAAGAAAAATGATAATTTATATGAAATGGAAAATTTTAATGATTG
CATTGTTAATGCCACAATTATTTCAAATGTTGAACTGCCTACAATGGATG
TAATAGTTAATGAAAATTTTGAAAACATCAATGAAAATCAGGATTTAAAA
AGAATTATTACCGAGAAAGATCAAATATTAAATAATACAGCTAAAGATAT
AGCTTCAAATAATGAACAAGTTAATGAAGCGTTTCAAGATTTACCAGCAG
TTATCCAAGAATCAATAAACAAAAGTGTTGATAATGTACCGGAAGTAACT
AATAAAGAAATAAAAGCAAAAAAGACTTTAGTTGAAGAGGTTAAGCCTTC
ATATAGGCTTAGAAGTTCAATTGGGACGTTAGAAGTATCCGATGAAGAAA
AAAAAGATAGAAAAAGAAATTCCACCCGAGTCAAGATGGCACCATTAAAA
GAGAAAAAAGTGTCCATTAATGAAGAAAATATTAGCTTTAATGACAAAGA
TGGAGTAGAAATTGCAAGTGATTTAACTACCCAATCGGCTGATGTTACAA
GACGAAAATCTTTACGAAGTTTCAAACGAGCAAATATTCAAAAAGAAAAT
TTAGAAACTCAACCTGCCAAGATAGAAATGAATTTATCAACTCCAAATAG
CAATTTAATCCAGGAAATGGATGATAATGATCCGGGAACATGGCCGGAAG
AAATCCCAGGTGAAATGAAAATCAAACTACTGAAAAAAGGACCGGTTCAA
TTGGAATTAACCGAGTACCCCAGAGACGAGAGAAATCGTTGCTTTCCTGC
ATTAAGTTATTTTTCAAAGAATTCGAAGAATGAAAGCATACGAAGATATT
GGTTGGTTTACTCTGCCAATAAGGATGCCGCATATTGTTTTCCATGTCGA
ATATTCGGTTACGATTCTCAGAGTTCATTAGCGAATTCAGGTTCGAGGAA
TTGGAAAAAGCTACAGGAGAGAATAAACTGTCACCAGGAATCTACAAAGC
ATAAAAGTTGTATGGAGCAATGGGCACAGTTCCCTCTTGATAGTGACAAT
TCGAAATGCGGACTTTCTCTGACCCATGAAGAAGCGCTGAAACTCGCTGG
ACAACTGAAGCATTTCTCATCAACGACAGATTACAAAATATATTTATTAG
CAAAACAATTGGAAACCGAACTATTGAACTTTGTTCGCGACGAGGGAGAA
GAAACAAGACAGAAATAGATATATAATTTTGATGTAATAAATTTTTACTT
AAACTATCATTTTTATGTGTTTAAATATTTATGTGCATTTTTTGAATAAA
TTTTTACTCTTATTGAAA
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protein sequence of SMED30010074-orf-1

>SMED30010074-orf-1 ID=SMED30010074-orf-1|Name=SMED30010074-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=506bp
MSKRNMEYEDYNDGKRQKINENNELNNSSPLLFFEDNYMTTENNNVCEMF
YDISCQNGSNGEEPYTVEPENKINEINLNSNGEIFKTEAVLNLEPTIENI
INKKNDNLYEMENFNDCIVNATIISNVELPTMDVIVNENFENINENQDLK
RIITEKDQILNNTAKDIASNNEQVNEAFQDLPAVIQESINKSVDNVPEVT
NKEIKAKKTLVEEVKPSYRLRSSIGTLEVSDEEKKDRKRNSTRVKMAPLK
EKKVSINEENISFNDKDGVEIASDLTTQSADVTRRKSLRSFKRANIQKEN
LETQPAKIEMNLSTPNSNLIQEMDDNDPGTWPEEIPGEMKIKLLKKGPVQ
LELTEYPRDERNRCFPALSYFSKNSKNESIRRYWLVYSANKDAAYCFPCR
IFGYDSQSSLANSGSRNWKKLQERINCHQESTKHKSCMEQWAQFPLDSDN
SKCGLSLTHEEALKLAGQLKHFSSTTDYKIYLLAKQLETELLNFVRDEGE
ETRQK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0046983protein dimerization activity
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0003677DNA binding
GO:0008270zinc ion binding
GO:0046872metal ion binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005654nucleoplasm
GO:0005737cytoplasm
Vocabulary: biological process
TermDefinition
GO:0006351transcription, DNA-templated
GO:0006355regulation of transcription, DNA-templated
GO:0006357regulation of transcription from RNA polymerase II promoter
GO:0007010cytoskeleton organization
GO:0007275multicellular organism development
GO:0022604regulation of cell morphogenesis
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..22
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..20
NoneNo IPR availablePANTHERPTHR45749FAMILY NOT NAMEDcoord: 296..440
NoneNo IPR availablePANTHERPTHR45749:SF1AC-LIKE TRANSPOSASE-RELATEDcoord: 296..440