Smed-notum

Overview


Name	Smed-notum (F8U830)
Smed ID	SMED30010051
Length (bp)	1917

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Smed-notum (SMED30010051) t-SNE clustered cells

Violin plots show distribution of expression levels for Smed-notum (SMED30010051) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Smed-notum (SMED30010051) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Smed-notum (SMED30010051) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30010051

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 27

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
anterior pole	SMED30010051	SMESG000004222.1	notum	smed_ncbi_20200123	PMID:24704339 Vogg et al., 2014
anterior pole	SMED30010051	SMESG000004222.1	notum	smed_ncbi_20200123	PMID:23318641 Chen et al., 2013
anterior pole	SMED30010051	SMESG000004222.1	notum	smed_ncbi_20200123	PMID:23318641 Chen et al., 2013
head region	SMED30010051	SMESG000004222.1	SMED30010051	smed_20140614	PMID:26525673 Hill et al., 2015
cholinergic neuron	SMED30010051	SMESG000004222.1	SMED30010051	smed_20140614	PMID:26525673 Hill et al., 2015
anterior pole	SMED30010051	SMESG000004222.1	SMED30010051	smed_20140614	PMID:26525673 Hill et al., 2015
anterior commissure	SMED30010051	SMESG000004222.1	SMED30010051	smed_20140614	PMID:26525673 Hill et al., 2015
central nervous system	SMED30010051	SMESG000004222.1	dd_Smed_v4_24180_0_1	dd_Smed_v4	PMID:27063937 Scimone et al., 2016
head region	SMED30010051	SMESG000004222.1	dd_Smed_v4_24180_0_1	dd_Smed_v4	PMID:27063937 Scimone et al., 2016
anterior pole	SMED30010051	SMESG000004222.1	dd_Smed_v4_24180_0_1	dd_Smed_v4	PMID:27063937 Scimone et al., 2016
anterior pole cell	SMED30010051	SMESG000004222.1	notum	smed_ncbi_20200123	PMID:24992682 Vásquez-Doorman et al., 2014
head region	SMED30010051	SMESG000004222.1	SmedASXL_009180	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
anterior side	SMED30010051	SMESG000004222.1	dd_Smed_v4_24180_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30010051	SMESG000004222.1	dd_Smed_v6_24180_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30010051	SMESG000004222.1	Contig11665	newmark_ests	PMID:27612384 Roberts-Galbraith et al., 2016
head region	SMED30010051	SMESG000004222.1	Contig11665	uc_Smed_v2	PMID:27612384 Roberts-Galbraith et al., 2016
anterior pole	SMED30010051	SMESG000004222.1	notum	smed_ncbi_20200123	PMID:24523458 Lin et al., 2014
reproductive organ	SMED30010051	SMESG000004222.1	Contig11665	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30010051	SMESG000004222.1	Contig11665	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
Category 2 cell	SMED30010051	SMESG000004222.1	dd_Smed_v4_24180_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
anterior pole	SMED30010051	SMESG000004222.1	notum	smed_ncbi_20200123	PMID:24415944 Scimone et al., 2014
anterior pole	SMED30010051	SMESG000004222.1	JF725701.1	smed_ncbi_20200123	PMID:27074666 Lander et al., 2016
anterior pole	SMED30010051	SMESG000004222.1	JF725701.1	smed_ncbi_20200123	PMID:21566195 Petersen et al., 2011
anterior pole	SMED30010051	SMESG000004222.1	JF725701.1	smed_ncbi_20200123	PMID:21566195 Petersen et al., 2011
anterior pole	SMED30010051	SMESG000004222.1	notum	smed_ncbi_20200123	PMID:21566195 Petersen et al., 2011
anterior pole	SMED30010051	SMESG000004222.1	notum	smed_ncbi_20200123	PMID:21566195 Petersen et al., 2011
anterior pole	SMED30010051	SMESG000004222.1	notum	smed_ncbi_20200123	PMID:26556349 Sureda-Gómez et al., 2015

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Smed-notum vs. Ensembl Human
Match: NOTUM (notum, palmitoleoyl-protein carboxylesterase [Source:HGNC Symbol;Acc:HGNC:27106])

HSP 1 Score: 246.514 bits (628), Expect = 1.154e-73
Identity = 156/454 (34.36%), Postives = 213/454 (46.92%), Query Frame = 1

Query:  307 TNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLY-FHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKV-----PILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKM 1650
            T+V CNDGS  GYY + S    S++WL+FLEGGWYCFN   C+SR  T   L SS  W   R   GILS+    NP + + N V+IPYCSSD+WSG   +     Y F G+ I+  VV +L   +       +   GSSAGG GVLLN+DR+  +L+K     + + G+ DS WFLD   YR ++C     C P  A+R G++ WN  +P RC++    G EW CF G  +Y  L+ P F++Q LFD+AQL +  V     P+ EG       YIQ LG     TL+     FA +C+ HEI+ +S+W  V V    L   L+ W   L                  K  K+P K                 L+DSC            PH                CNP+C  +    +G  M+    L      +  +A+  G+   +L  M
Sbjct:   97 TSVTCNDGSPAGYYLKESRG--SRRWLLFLEGGWYCFNRENCDSRYDTMRRLMSSRDWPRTRTGTGILSSQPEENPYWWNANMVFIPYCSSDVWSGASSKSEKNEYAFMGALIIQEVVRELL-GRGLSGAKVLLLAGSSAGGTGVLLNVDRVAEQLEKLGYPAIQVRGLADSGWFLDNKQYRHTDCVDTITCAPTEAIRRGIRYWNGVVPERCRRQFQEGEEWNCFFGYKVYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEG----LRLYIQNLGRELRHTLKDVPASFAPACLSHEIIIRSHWTDVQVKGTSLPRALHCWDRSLH--------------DSHKASKTPLKG------------CPVHLVDSC----------PWPH----------------CNPSCPTVRDQFTGQEMNVAQFLMHMGFDMQTVAQPQGLEPSELLGM 491

[Close]

BLAST of Smed-notum vs. Ensembl Human
Match: NOTUM (notum, palmitoleoyl-protein carboxylesterase [Source:HGNC Symbol;Acc:HGNC:27106])

HSP 1 Score: 162.155 bits (409), Expect = 1.835e-44
Identity = 88/202 (43.56%), Postives = 116/202 (57.43%), Query Frame = 1

Query:  307 TNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLY-FHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGM 909
            T+V CNDGS  GYY + S    S++WL+FLEGGWYCFN   C+SR  T   L SS  W   R   GILS+    NP + + N V+IPYCSSD+WSG   +     Y F G+ I+  VV +L   +       +   GSSAGG GVLLN+DR+  +L+K     + + G+ DS WFLD   YR ++C     C P  A+R G+
Sbjct:   97 TSVTCNDGSPAGYYLKESRG--SRRWLLFLEGGWYCFNRENCDSRYDTMRRLMSSRDWPRTRTGTGILSSQPEENPYWWNANMVFIPYCSSDVWSGASSKSEKNEYAFMGALIIQEVVRELL-GRGLSGAKVLLLAGSSAGGTGVLLNVDRVAEQLEKLGYPAIQVRGLADSGWFLDNKQYRHTDCVDTITCAPTEAIRRGI 295

[Close]

BLAST of Smed-notum vs. Ensembl Human
Match: NOTUM (notum, palmitoleoyl-protein carboxylesterase [Source:HGNC Symbol;Acc:HGNC:27106])

HSP 1 Score: 147.902 bits (372), Expect = 1.718e-40
Identity = 78/195 (40.00%), Postives = 108/195 (55.38%), Query Frame = 1

Query:  460 LFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLY-FHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLF 1041
            L SS  W   R   GILS+    NP + + N V+IPYCSSD+WSG   +     Y F G+ I+  VV +L   +       +   GSSAGG GVLLN+DR+  +L+K     + + G+ DS WFLD   YR ++C     C P  A+R G++ WN  +P RC++    G EW CF G  +Y  L+ P F++Q LF
Sbjct:    4 LMSSRDWPRTRTGTGILSSQPEENPYWWNANMVFIPYCSSDVWSGASSKSEKNEYAFMGALIIQEVVRELL-GRGLSGAKVLLLAGSSAGGTGVLLNVDRVAEQLEKLGYPAIQVRGLADSGWFLDNKQYRHTDCVDTITCAPTEAIRRGIRYWNGVVPERCRRQFQEGEEWNCFFGYKVYPTLRCPVFVVQWLF 197

[Close]

BLAST of Smed-notum vs. Ensembl Fly
Match: Notum (gene:FBgn0044028 transcript:FBtr0075435)

HSP 1 Score: 211.846 bits (538), Expect = 1.543e-59
Identity = 127/350 (36.29%), Postives = 189/350 (54.00%), Query Frame = 1

Query:  244 SSNSIHSRKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLE-----KTNGLYFHGSRILDTVVDDLTQNQHFKKV--HEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKV--PILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQ 1266
            S +  HSR  +   L     +T++ CNDGS  G+Y R   +  SKKW++ LEGGW+CF+  +C SR      L +S  W   R +GGILS +   NP +H+ N V IPYCSSD WSG + E     + N   F G+ IL  V+ +L       +V   E+  VGSSAGG+GV+LN+DR++  L  + K ++ + G+ DS WFLD   Y  +            A+R G KLW   +P  C K       W+C+ G  +Y  LK P F+ Q LFD+AQ+++  V  P+    + ++++YI ++GG    +L     VFA SC+ H +L K +W  + +++  L   L  W+
Sbjct:   79 SGSGDHSRSLKRANLA----NTSITCNDGSHAGFYLRKHPS--SKKWIVLLEGGWHCFDVRSCRSRWMRLRHLMTSSQWPETRDVGGILSPHPEENPYWHNANHVLIPYCSSDSWSGTRTEPDTSDRENSWRFMGALILRQVIAELIP-VGLGRVPGGELMLVGSSAGGMGVMLNLDRIRDFLVNEKKLQITVRGVSDSGWFLDREPYTPAAVAS------NEAVRQGWKLWQGLLPEECTKSYPT-EPWRCYYGYRLYPTLKTPLFVFQWLFDEAQMRVDNVGAPV----TPQQWNYIHEMGGALRSSLDNVSAVFAPSCIGHGVLFKRDWVNIKIDDISLPSALRCWE 410

HSP 2 Score: 50.8322 bits (120), Expect = 3.980e-6
Identity = 23/71 (32.39%), Postives = 40/71 (56.34%), Query Frame = 1

Query: 1465 RTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKMNTQQQISLL 1677
            R L RC+      P CN +C  L++P++G  M F++LL  + + I  +A +LG+ M  L  M   + +++L
Sbjct:  601 RLLERCS-----WPQCNHSCPTLTNPMTGEEMRFLELLTAFGLDIEAVAAALGVDMHTLNNMERTELVNML 666

[Close]

BLAST of Smed-notum vs. Ensembl Zebrafish
Match: notum1a (notum, palmitoleoyl-protein carboxylesterase a [Source:NCBI gene;Acc:570510])

HSP 1 Score: 249.595 bits (636), Expect = 6.196e-75
Identity = 161/479 (33.61%), Postives = 224/479 (46.76%), Query Frame = 1

Query:  232 NDPQSSNSIHSRKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLY-FHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKV-----PILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKM 1650
            N  QS     ++K  Y     F  +T+V CNDG+  GYY + S    SK+WLIFLEGGWYCFN   C+SR  T   L SS  W   +   G+LS+    NP++ + N V+IPYCSSD+WSG   +     Y F GS I+  VV DL  ++       +   GSSAGG GVLLN+D +   L++     + + G+ DS WFLD   YR ++C     C P   ++ G+K W   +P RC++    G+EW CF G  +Y  +K P FI+Q LFD+AQL +  +     P+ EG    ++ YIQ LG     TL+    +FA +C+ HE +T++ W  V V    L   L+ W   L+                 +  KSP K                 LIDSC            PH                CNPTC  +    +G  M+ I  L      +  +A   G+   +L  M
Sbjct:   77 NLAQSLYPCSAQKLDYDMKLHFLENTSVTCNDGTPAGYYLKESKG--SKRWLIFLEGGWYCFNKENCDSRYETMRRLMSSSKWPQTKTGTGMLSSLPEENPHWWNANMVFIPYCSSDVWSGASPKTDQNDYAFMGSLIIKEVVKDLL-SKGLDNAKILLLAGSSAGGTGVLLNVDSVSELLEELGHTNIQVRGLSDSGWFLDNKQYRCTDCVDTINCAPTEVIKRGIKYWGGVVPERCRQAY-EGKEWNCFFGYKVYPTIKRPVFIVQWLFDEAQLTVDNIHLTGQPVQEG----QWRYIQNLGTELRNTLKDVPAMFAPACLSHEFITRNYWTDVQVKGTSLPRALHCWDRSLQ--------------DTSRNNKSPPKG------------CPVHLIDSC----------PWPH----------------CNPTCPTIRDQSTGQEMNVIQFLMHMGFDVQKMAHQQGMDPSKLLGM 495

[Close]

BLAST of Smed-notum vs. Ensembl Zebrafish
Match: notum2 (Danio rerio notum pectinacetylesterase 2 (notum2), mRNA. [Source:RefSeq mRNA;Acc:NM_001353872])

HSP 1 Score: 236.498 bits (602), Expect = 4.499e-70
Identity = 122/330 (36.97%), Postives = 188/330 (56.97%), Query Frame = 1

Query:  295 FPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLE------KTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPI-LEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYW 1263
            F  +T V CNDG+  G+Y +      SK+WLIFLEGGW C++  TC+SR +T   L  S  W   R+  G+LS     NP++++ N V++PYCSSD+WSG +        K     F GS+I+  V+ DL   +  K+   V   G+SAGG GVLLNID++   L+++      + G+VDS WFL+    +  +C     C P +A++ G++LWN  +P +CK+   RG +W CF G  +Y ++  P F++Q LFD+ QL++  + +  +  S ++++Y+Q LG     +L+    VFA SC+ H ++TKSNW    +    L   L  W
Sbjct:   90 FLKNTAVTCNDGTAAGFYLK--EFKGSKRWLIFLEGGWCCYSKETCDSRYKTIPRLMGSTDWPQTRRGSGLLSAQVDENPHWYNANIVFVPYCSSDVWSGNKAASKPKQGKETEYAFMGSQIIREVIKDLVP-KGLKQAKVVMLAGTSAGGTGVLLNIDKVSSLLEQQGAE-AQVRGLVDSGWFLESKQQKVPDCPDSASCTPADAIKKGLRLWNGVVPEKCKQQYKRGEDWHCFFGHKLYSYISAPLFVVQWLFDEEQLRVENIYMGSQSLSEQQWTYMQNLGKELKNSLKDVTAVFAPSCLSHTLITKSNWTDFQIKGTSLSRALQCW 415

[Close]

Query:  295 FPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLE------KTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPI-LEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYW 1263
            F  +T V CNDG+  G+Y +      SK+WLIFLEGGW C++  TC+SR +T   L  S  W   R+  G+LS     NP++++ N V++PYCSSD+WSG +        K     F GS+I+  V+ DL   +  K+   V   G+SAGG GVLLNID++   L+++      + G+VDS WFL+    +  +C     C P +A++ G++LWN  +P +CK+   RG +W CF G  +Y ++  P F++Q LFD+ QL++  + +  +  S ++++Y+Q LG     +L+    VFA SC+ H ++TKSNW    +    L   L  W
Sbjct:   90 FLKNTAVTCNDGTAAGFYLK--EFKGSKRWLIFLEGGWCCYSKETCDSRYKTIPRLMGSTDWPQTRRGSGLLSAQVDENPHWYNANIVFVPYCSSDVWSGNKAASKPKQGKETEYAFMGSQIIREVIKDLVP-KGLKQAKVVMLAGTSAGGTGVLLNIDKVSSLLEQQGAE-AQVRGLVDSGWFLESKQQKVPDCPDSASCTPADAIKKGLRLWNGVVPEKCKQQYKRGEDWHCFFGHKLYSYISAPLFVVQWLFDEEQLRVENIYMGSQSLSEQQWTYMQNLGKELKNSLKDVTAVFAPSCLSHTLITKSNWTDFQIKGTSLSRALQCW 415

[Close]

BLAST of Smed-notum vs. Ensembl Xenopus
Match: notum (notum, palmitoleoyl-protein carboxylesterase [Source:NCBI gene;Acc:100145278])

HSP 1 Score: 250.751 bits (639), Expect = 2.399e-75
Identity = 150/450 (33.33%), Postives = 218/450 (48.44%), Query Frame = 1

Query:  310 NVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLE-KTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKV-----PILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQL 1641
            +V CNDGS  GYY + S    S++WL+FLEGGWYC +   C+ R  T   L SS+ W   +   GILS     NP++ + N V+IPYCSSD+WSG   + + +G  F GS I+  VV +L   +       +   GSSAGG GVLLN+D +  +L++     + + G+ DS WFLD   YR+++CT I  C P  A++ G++ WN  +P RCK+    G EW CF G  IY  L++P F++Q LFD+AQL +  V     P+ E     ++ YIQ LG     TL+     FA +C+ HE++T+S+W  + V    L   L+ W   L+                        KN + P     +    + L+DSC                            P CNPTC  +    +G  MS +  L      +  +A   G+   +L
Sbjct:   92 SVTCNDGSPAGYYLKESKG--SRRWLVFLEGGWYCISRENCDLRYDTMRRLMSSKAWPPAKTASGILSTQPEENPHWWNANMVFIPYCSSDVWSGASPKTEKSGYAFMGSLIIQEVVKELL-GKGLDTAKVLLLAGSSAGGTGVLLNVDLVADQLEELGFPGIQVRGLSDSGWFLDNKQYRRTDCTDIITCAPTEAIQRGIRYWNSVVPERCKQQFKEGEEWNCFFGYKIYPTLRSPVFVVQWLFDEAQLTVDNVHLSGQPVQE----SQWLYIQNLGQELRNTLKDVGASFAPACLAHEVITRSHWTEIQVRGTSLPRALHCWDRSLQETN---------------------KNSKVP-----LKGCPFHLMDSCP--------------------------WPQCNPTCPSIRDHFTGQEMSVVQFLMHLGFDVQKMASQQGMEPGKL 482

[Close]

BLAST of Smed-notum vs. Ensembl Xenopus
Match: notum (notum, palmitoleoyl-protein carboxylesterase [Source:NCBI gene;Acc:100145278])

HSP 1 Score: 250.751 bits (639), Expect = 2.539e-75
Identity = 150/450 (33.33%), Postives = 218/450 (48.44%), Query Frame = 1

Query:  310 NVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLE-KTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKV-----PILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQL 1641
            +V CNDGS  GYY + S    S++WL+FLEGGWYC +   C+ R  T   L SS+ W   +   GILS     NP++ + N V+IPYCSSD+WSG   + + +G  F GS I+  VV +L   +       +   GSSAGG GVLLN+D +  +L++     + + G+ DS WFLD   YR+++CT I  C P  A++ G++ WN  +P RCK+    G EW CF G  IY  L++P F++Q LFD+AQL +  V     P+ E     ++ YIQ LG     TL+     FA +C+ HE++T+S+W  + V    L   L+ W   L+                        KN + P     +    + L+DSC                            P CNPTC  +    +G  MS +  L      +  +A   G+   +L
Sbjct:   95 SVTCNDGSPAGYYLKESKG--SRRWLVFLEGGWYCISRENCDLRYDTMRRLMSSKAWPPAKTASGILSTQPEENPHWWNANMVFIPYCSSDVWSGASPKTEKSGYAFMGSLIIQEVVKELL-GKGLDTAKVLLLAGSSAGGTGVLLNVDLVADQLEELGFPGIQVRGLSDSGWFLDNKQYRRTDCTDIITCAPTEAIQRGIRYWNSVVPERCKQQFKEGEEWNCFFGYKIYPTLRSPVFVVQWLFDEAQLTVDNVHLSGQPVQE----SQWLYIQNLGQELRNTLKDVGASFAPACLAHEVITRSHWTEIQVRGTSLPRALHCWDRSLQETN---------------------KNSKVP-----LKGCPFHLMDSCP--------------------------WPQCNPTCPSIRDHFTGQEMSVVQFLMHLGFDVQKMASQQGMEPGKL 485

[Close]

BLAST of Smed-notum vs. Ensembl Xenopus
Match: prdm5 (PR domain 5 [Source:Xenbase;Acc:XB-GENE-854777])

HSP 1 Score: 228.794 bits (582), Expect = 3.932e-67
Identity = 141/441 (31.97%), Postives = 212/441 (48.07%), Query Frame = 1

Query:  259 HSRKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPI-LEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLL 1578
            H +K Q      F  +T V CNDG+  GYY R +    SK+W+IFLEGGW C++  TC  R      L SS  W   R+  GI+S     NP + + N+V++PYCSSD+WSG   +  +G  F GS I+  V+ DL   +  K+   V   GSSAGG GVL+NIDR+   +++     + + G+VDS WFLD    +QS+C  I +C    A++ G+KLWN  +P  CK+   +G EW+CF GP ++  +K+P F++Q L+D  QL++  +    +  +  +++ IQ +G    ++LR+         +   I    NW    V +  L + L+ W   L+                           R PK +  I    + LID+C          Q PH                CNPTC  +    SG  +S + + 
Sbjct:   73 HDQKSQEDMKLHFLKNTMVTCNDGTTAGYYLREAKG--SKRWIIFLEGGWCCYSKETCGIRYDNIKRLMSSSNWPQTRKGSGIISPRPDENPYWWNVNAVFVPYCSSDVWSGNISKTQDGYAFMGSVIIQEVIRDLVP-RGLKQAKSVILAGSSAGGTGVLINIDRVAALVEEITSESIQVRGLVDSGWFLDSKHAKQSDCLDISKCALTEAIKKGLKLWNGILPENCKQQLKKGDEWRCFYGPRVFASMKSPIFVVQWLYDQEQLRIENIQTEFQSMTENQWNSIQNIGREFKKSLREVP-------LKSHISGIHNWLEFQVKSVTLAKALHCWDRSLQEN-------------------------RAPKAA--IRGCPFHLIDNC----------QWPH----------------CNPTCPAIYDSTSGQEVSILQMF 450

[Close]

BLAST of Smed-notum vs. Ensembl Xenopus
Match: notum (notum, palmitoleoyl-protein carboxylesterase [Source:NCBI gene;Acc:100145278])

HSP 1 Score: 223.787 bits (569), Expect = 2.265e-65
Identity = 145/450 (32.22%), Postives = 209/450 (46.44%), Query Frame = 1

Query:  310 NVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLE-KTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKV-----PILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQL 1641
            +V CNDGS  GYY + S    S++WL+FLEGGWYC +   C+ R  T   L SS+ W   +   GILS     NP++ + N V+IPYCSSD+WSG   + + +G  F GS I+  VV +L   +       +   GSSAGG GVLLN+D +  +L++     + + G+ DS WFLD   YR+++CT I  C P  A++ G++ WN  +P RCK+    G EW CF G  IY  L++P F++Q LFD+AQL +  V     P+ E     ++ YIQ LG     TL+         CV  + L  +    + V    L   L+ W   L+                        KN + P     +    + L+DSC                            P CNPTC  +    +G  MS +  L      +  +A   G+   +L
Sbjct:   92 SVTCNDGSPAGYYLKESKG--SRRWLVFLEGGWYCISRENCDLRYDTMRRLMSSKAWPPAKTASGILSTQPEENPHWWNANMVFIPYCSSDVWSGASPKTEKSGYAFMGSLIIQEVVKELL-GKGLDTAKVLLLAGSSAGGTGVLLNVDLVADQLEELGFPGIQVRGLSDSGWFLDNKQYRRTDCTDIITCAPTEAIQRGIRYWNSVVPERCKQQFKEGEEWNCFFGYKIYPTLRSPVFVVQWLFDEAQLTVDNVHLSGQPVQE----SQWLYIQNLGQELRNTLKDV------GCVSSDTLNYT----IQVRGTSLPRALHCWDRSLQETN---------------------KNSKVP-----LKGCPFHLMDSCP--------------------------WPQCNPTCPSIRDHFTGQEMSVVQFLMHLGFDVQKMASQQGMEPGKL 472

[Close]

BLAST of Smed-notum vs. Ensembl Xenopus
Match: notum (notum, palmitoleoyl-protein carboxylesterase [Source:NCBI gene;Acc:100145278])

HSP 1 Score: 202.216 bits (513), Expect = 1.363e-57
Identity = 134/449 (29.84%), Postives = 193/449 (42.98%), Query Frame = 1

Query:  310 NVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKV-----PILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQL 1641
            +V CNDGS  GYY + S    S++WL+FLEGGWYC +   C+ R  T   L SS+ W                                          KT G  F GS I+  VV +L   +       +   GSSAGG GVLLN+D +  +L++     + + G+ DS WFLD   YR+++CT I  C P  A++ G++ WN  +P RCK+    G EW CF G  IY  L++P F++Q LFD+AQL +  V     P+ E     ++ YIQ LG     TL+     FA +C+ HE++T+S+W  + V    L   L+ W   L+                        KN + P     +    + L+DSC                            P CNPTC  +    +G  MS +  L      +  +A   G+   +L
Sbjct:   92 SVTCNDGSPAGYYLKESKG--SRRWLVFLEGGWYCISRENCDLRYDTMRRLMSSKAWPPA---------------------------------------KTGGYAFMGSLIIQEVVKELL-GKGLDTAKVLLLAGSSAGGTGVLLNVDLVADQLEELGFPGIQVRGLSDSGWFLDNKQYRRTDCTDIITCAPTEAIQRGIRYWNSVVPERCKQQFKEGEEWNCFFGYKIYPTLRSPVFVVQWLFDEAQLTVDNVHLSGQPVQE----SQWLYIQNLGQELRNTLKDVGASFAPACLAHEVITRSHWTEIQVRGTSLPRALHCWDRSLQETN---------------------KNSKVP-----LKGCPFHLMDSCP--------------------------WPQCNPTCPSIRDHFTGQEMSVVQFLMHLGFDVQKMASQQGMEPGKL 442

[Close]

BLAST of Smed-notum vs. Ensembl Mouse
Match: Notum (notum palmitoleoyl-protein carboxylesterase [Source:MGI Symbol;Acc:MGI:1924833])

HSP 1 Score: 250.751 bits (639), Expect = 2.306e-75
Identity = 155/454 (34.14%), Postives = 218/454 (48.02%), Query Frame = 1

Query:  307 TNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLY-FHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKV-----PILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKM 1650
            T+V CNDGS  GYY + S    S++WL+FLEGGWYCFN   C+SR  T   L SS+ W   R   GILS+    NP++ + N V+IPYCSSD+WSG   +     Y F GS I+  VV +L   +       +   GSSAGG GVLLN+DR+   L++     + + G+ DS WFLD   YR+S+C     C P +A+R G++ W+  +P RC++    G EW CF G  +Y  L+ P F++Q LFD+AQL +  V     P+ EG    ++ YIQ LG     TL+  +  FA +C+ HEI+ +S W  V V    L   L+ W                      K  K+P K               + L+DSC            PH                CNP+C  +    +G  M+    L      +  +A+  G+   +L  M
Sbjct:  104 TSVTCNDGSPAGYYLKESKG--SRRWLLFLEGGWYCFNRENCDSRYSTMRRLMSSKDWPHTRTGTGILSSQPEENPHWWNANMVFIPYCSSDVWSGASPKSDKNEYAFMGSLIIQEVVRELL-GKGLSGAKVLLLAGSSAGGTGVLLNVDRVAELLEELGYPSIQVRGLADSGWFLDNKQYRRSDCIDTINCAPTDAIRRGIRYWSGMVPERCQRQFKEGEEWNCFFGYKVYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEG----QWLYIQNLGRELRGTLKDVQASFAPACLSHEIIIRSYWTDVQVKGTSLPRALHCWDRSFH--------------DSHKASKTPMKG------------CPFHLVDSC----------PWPH----------------CNPSCPTIRDQFTGQEMNVAQFLMHMGFDVQTVAQQQGMEPSKLLGM 498

[Close]

Query:  307 TNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLY-FHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKV-----PILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKM 1650
            T+V CNDGS  GYY + S    S++WL+FLEGGWYCFN   C+SR  T   L SS+ W   R   GILS+    NP++ + N V+IPYCSSD+WSG   +     Y F GS I+  VV +L   +       +   GSSAGG GVLLN+DR+   L++     + + G+ DS WFLD   YR+S+C     C P +A+R G++ W+  +P RC++    G EW CF G  +Y  L+ P F++Q LFD+AQL +  V     P+ EG    ++ YIQ LG     TL+  +  FA +C+ HEI+ +S W  V V    L   L+ W                      K  K+P K               + L+DSC            PH                CNP+C  +    +G  M+    L      +  +A+  G+   +L  M
Sbjct:  104 TSVTCNDGSPAGYYLKESKG--SRRWLLFLEGGWYCFNRENCDSRYSTMRRLMSSKDWPHTRTGTGILSSQPEENPHWWNANMVFIPYCSSDVWSGASPKSDKNEYAFMGSLIIQEVVRELL-GKGLSGAKVLLLAGSSAGGTGVLLNVDRVAELLEELGYPSIQVRGLADSGWFLDNKQYRRSDCIDTINCAPTDAIRRGIRYWSGMVPERCQRQFKEGEEWNCFFGYKVYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEG----QWLYIQNLGRELRGTLKDVQASFAPACLSHEIIIRSYWTDVQVKGTSLPRALHCWDRSFH--------------DSHKASKTPMKG------------CPFHLVDSC----------PWPH----------------CNPSCPTIRDQFTGQEMNVAQFLMHMGFDVQTVAQQQGMEPSKLLGM 498

[Close]

BLAST of Smed-notum vs. Ensembl Mouse
Match: Notum (notum palmitoleoyl-protein carboxylesterase [Source:MGI Symbol;Acc:MGI:1924833])

HSP 1 Score: 106.301 bits (264), Expect = 1.095e-25
Identity = 56/114 (49.12%), Postives = 71/114 (62.28%), Query Frame = 1

Query:  307 TNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLY-FHGSRIL 645
            T+V CNDGS  GYY + S    S++WL+FLEGGWYCFN   C+SR  T   L SS+ W   R   GILS+    NP++ + N V+IPYCSSD+WSG   +     Y F GS I+
Sbjct:  104 TSVTCNDGSPAGYYLKESKG--SRRWLLFLEGGWYCFNRENCDSRYSTMRRLMSSKDWPHTRTGTGILSSQPEENPHWWNANMVFIPYCSSDVWSGASPKSDKNEYAFMGSLII 215

[Close]

BLAST of Smed-notum vs. UniProt/SwissProt
Match: sp|F8U830|NOTUM_SCHMD (Palmitoleoyl-protein carboxylesterase NOTUM OS=Schmidtea mediterranea OX=79327 GN=notum PE=2 SV=1)

HSP 1 Score: 962.6 bits (2487), Expect = 0.000e+0
Identity = 496/496 (100.00%), Postives = 496/496 (100.00%), Query Frame = 1

Query:  205 LIFDRINKLNDPQSSNSIHSRKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKMNTQQQISLLYCSSR 1692
            LIFDRINKLNDPQSSNSIHSRKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDRLKRRLKKKLKRKVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEKKKIKKKVQKNPKLIKTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKMNTQQQISLLYCSSR
Sbjct:   32 LIFDRINKLNDPQSSNSIHSRKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDRLKRRLKKKLKRKVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEKKKIKKKVQKNPKLIKTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKMNTQQQISLLYCSSR 527

[Close]

BLAST of Smed-notum vs. UniProt/SwissProt
Match: sp|A0A0D3QS97|NOTU2_XENLA (Palmitoleoyl-protein carboxylesterase notum2 OS=Xenopus laevis OX=8355 GN=notum2 PE=2 SV=1)

HSP 1 Score: 257.684 bits (657), Expect = 2.796e-77
Identity = 148/429 (34.50%), Postives = 219/429 (51.05%), Query Frame = 1

Query:  295 FPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPI-LEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLL 1578
            F  +T V CNDG+  GYY R   T  SK+W+IFLEGGW C++  TC  R      L SS  W   R+  GILS  +  NP + + N+V++PYCSSD+WSG   +  +G  F GS I+  V+ DL   +  K+   V   GSSAGG GVL+NIDR+   +++     V + G+VDS WFLD    +QS+C  I +C    A++ G+KLWN  +P  CK+   +G EW+CF GP ++  +K+P F++Q L+D  QL++  +    +  +  +++ IQ +G    ++LR+   VFA +C+ H ++TKSNW    V +  L + L+ W   L+                           R PK  G I    + L+D+C          Q PH                CNPTC  +    SG  +S + + 
Sbjct:   85 FLKNTLVTCNDGTTAGYYLR--ETKGSKRWIIFLEGGWCCYSKETCGVRYDNVKRLMSSSNWPQTRKGTGILSPRQDENPYWWNVNAVFVPYCSSDVWSGNVSKTQDGYAFMGSVIIQEVIRDLVP-RGMKQAKSVILAGSSAGGTGVLINIDRVAALVEETTSESVQVRGLVDSGWFLDSRHSKQSDCLDISKCALTEAIKKGLKLWNGILPENCKQQFKKGDEWRCFYGPRLFTSMKSPIFVVQWLYDQEQLRIENIQTEFQSMTENQWNSIQNIGREFKKSLREVPAVFAPACLSHTLITKSNWLEFQVKSVTLAKALHCWDRSLQEN-------------------------RAPK--GVIRGCPFHLVDNC----------QWPH----------------CNPTCPAIYDATSGQELSILQMF 457

[Close]

BLAST of Smed-notum vs. UniProt/SwissProt
Match: sp|Q8R116|NOTUM_MOUSE (Palmitoleoyl-protein carboxylesterase NOTUM OS=Mus musculus OX=10090 GN=Notum PE=1 SV=2)

HSP 1 Score: 250.751 bits (639), Expect = 1.613e-74
Identity = 155/454 (34.14%), Postives = 218/454 (48.02%), Query Frame = 1

Query:  307 TNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLY-FHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKV-----PILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKM 1650
            T+V CNDGS  GYY + S    S++WL+FLEGGWYCFN   C+SR  T   L SS+ W   R   GILS+    NP++ + N V+IPYCSSD+WSG   +     Y F GS I+  VV +L   +       +   GSSAGG GVLLN+DR+   L++     + + G+ DS WFLD   YR+S+C     C P +A+R G++ W+  +P RC++    G EW CF G  +Y  L+ P F++Q LFD+AQL +  V     P+ EG    ++ YIQ LG     TL+  +  FA +C+ HEI+ +S W  V V    L   L+ W                      K  K+P K               + L+DSC            PH                CNP+C  +    +G  M+    L      +  +A+  G+   +L  M
Sbjct:  104 TSVTCNDGSPAGYYLKESKG--SRRWLLFLEGGWYCFNRENCDSRYSTMRRLMSSKDWPHTRTGTGILSSQPEENPHWWNANMVFIPYCSSDVWSGASPKSDKNEYAFMGSLIIQEVVRELL-GKGLSGAKVLLLAGSSAGGTGVLLNVDRVAELLEELGYPSIQVRGLADSGWFLDNKQYRRSDCIDTINCAPTDAIRRGIRYWSGMVPERCQRQFKEGEEWNCFFGYKVYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEG----QWLYIQNLGRELRGTLKDVQASFAPACLSHEIIIRSYWTDVQVKGTSLPRALHCWDRSFH--------------DSHKASKTPMKG------------CPFHLVDSC----------PWPH----------------CNPSCPTIRDQFTGQEMNVAQFLMHMGFDVQTVAQQQGMEPSKLLGM 498

[Close]

BLAST of Smed-notum vs. UniProt/SwissProt
Match: sp|A0A0D3QS99|NOT1_XENLA (Palmitoleoyl-protein carboxylesterase notum1 OS=Xenopus laevis OX=8355 GN=notum1 PE=2 SV=1)

HSP 1 Score: 249.21 bits (635), Expect = 4.331e-74
Identity = 149/450 (33.11%), Postives = 218/450 (48.44%), Query Frame = 1

Query:  310 NVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLE-KTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKV-----PILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQL 1641
            +V CNDGS  GYY + S    S++WL+FLEGGWYC ++  C+ R  T   L SS+ W   +   GILS     NP++ + N V+IPYCSSD+WSG   + + +G  F GS I+  VV +L   +       +   GSSAGG GVLLN+D +   L++     + + G+ DS WFLD   YR+++CT I  C P  A++ G++ W+  +P RCK+    G EW CF G  IY  L++P F++Q LFD+AQL +  V     P+ E     ++ YIQ LG     TL+     FA +C+ HE++T+S+W  + V    L   L+ W   L+                        KN + P     +    + L+DSC                            P CNPTC  +    +G  MS +  L      +  +A   G+   +L
Sbjct:   92 SVTCNDGSSAGYYLKESKG--SRRWLVFLEGGWYCISHENCDLRYDTMRRLMSSKAWPPAKTASGILSTQPEENPHWWNANMVFIPYCSSDVWSGASPKTEKSGYAFMGSLIIQEVVKELL-GKGLDAAKVLLLAGSSAGGTGVLLNVDLVADLLEELGYPGIQVRGLSDSGWFLDNKQYRRTDCTDIITCAPTEAIQRGIRYWSSMVPERCKQQFKEGEEWNCFFGYKIYPTLRSPVFVVQWLFDEAQLTVDNVHLSGQPVQE----SQWLYIQNLGRELRNTLKDVGASFAPACLAHEVITRSHWTEIQVRGTSLPRALHCWDRRLQETN---------------------KNSKVP-----LKGCPFHLMDSCP--------------------------WPQCNPTCPSIRDHFTGQEMSVVQFLMHLGFDVQKMASQQGMEPGKL 482

[Close]

BLAST of Smed-notum vs. UniProt/SwissProt
Match: sp|C5H5C4|NOT1A_DANRE (Palmitoleoyl-protein carboxylesterase notum1a OS=Danio rerio OX=7955 GN=notum1a PE=2 SV=1)

HSP 1 Score: 249.595 bits (636), Expect = 4.677e-74
Identity = 161/479 (33.61%), Postives = 224/479 (46.76%), Query Frame = 1

Query:  232 NDPQSSNSIHSRKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLY-FHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKV-----PILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKM 1650
            N  QS     ++K  Y     F  +T+V CNDG+  GYY + S    SK+WLIFLEGGWYCFN   C+SR  T   L SS  W   +   G+LS+    NP++ + N V+IPYCSSD+WSG   +     Y F GS I+  VV DL  ++       +   GSSAGG GVLLN+D +   L++     + + G+ DS WFLD   YR ++C     C P   ++ G+K W   +P RC++    G+EW CF G  +Y  +K P FI+Q LFD+AQL +  +     P+ EG    ++ YIQ LG     TL+    +FA +C+ HE +T++ W  V V    L   L+ W   L+                 +  KSP K                 LIDSC            PH                CNPTC  +    +G  M+ I  L      +  +A   G+   +L  M
Sbjct:   77 NLAQSLYPCSAQKLDYDMKLHFLENTSVTCNDGTPAGYYLKESKG--SKRWLIFLEGGWYCFNKENCDSRYETMRRLMSSSKWPQTKTGTGMLSSLPEENPHWWNANMVFIPYCSSDVWSGASPKTDQNDYAFMGSLIIKEVVKDLL-SKGLDNAKILLLAGSSAGGTGVLLNVDSVSELLEELGHTNIQVRGLSDSGWFLDNKQYRCTDCVDTINCAPTEVIKRGIKYWGGVVPERCRQAY-EGKEWNCFFGYKVYPTIKRPVFIVQWLFDEAQLTVDNIHLTGQPVQEG----QWRYIQNLGTELRNTLKDVPAMFAPACLSHEFITRNYWTDVQVKGTSLPRALHCWDRSLQ--------------DTSRNNKSPPKG------------CPVHLIDSC----------PWPH----------------CNPTCPTIRDQSTGQEMNVIQFLMHMGFDVQKMAHQQGMDPSKLLGM 495

[Close]

BLAST of Smed-notum vs. TrEMBL
Match: A0A481SAC8 (Notum (Fragment) OS=Dugesia japonica OX=6161 PE=2 SV=1)

HSP 1 Score: 858.596 bits (2217), Expect = 0.000e+0
Identity = 435/490 (88.78%), Postives = 461/490 (94.08%), Query Frame = 1

Query:  232 NDPQSSNSIHSRKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKF---SGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKMNTQQQISLLYCSSR 1692
            ND QSS SIHSRKYQYFQL KFPNS+NVRCNDGS+PGYYTRPS +NCSKKWLIFLEGGWYCFNNNTCE RRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYN+VYIPYCSSDLWSGKQ+EKT+GLYFHGSRILDTV+DDL  N +FKKV EVAFVGSSAGGIGVLLNIDRLKRR+KKKLKRKVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALR GMKLWNPRIPRRCKKFQGRG+EWKCFMGPVIYRHLKNP FIIQSLFDDAQLQMSKVPILEGGSNKKFSYIQQLGGFA+QTLRQAKGVFAHSCVDHEILTKSNWAY+SVNNQ LHETLN+WQ YL+ EKKKIKKK  +N K+ K  KS CKN+RKPK    SG ++ S+YQLIDSCHISQIT+YKIQLPHNRTLSRCA+AIPLIPLCNPTCSPLSHPISGL MSFIDLLELYNVRINLIAKSLG++M+ LRKM+TQQQISLLYCSSR
Sbjct:    1 NDQQSSGSIHSRKYQYFQLNKFPNSSNVRCNDGSVPGYYTRPSASNCSKKWLIFLEGGWYCFNNNTCELRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNAVYIPYCSSDLWSGKQIEKTDGLYFHGSRILDTVIDDLIINHNFKKVQEVAFVGSSAGGIGVLLNIDRLKRRMKKKLKRKVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRKGMKLWNPRIPRRCKKFQGRGKEWKCFMGPVIYRHLKNPVFIIQSLFDDAQLQMSKVPILEGGSNKKFSYIQQLGGFASQTLRQAKGVFAHSCVDHEILTKSNWAYISVNNQCLHETLNFWQVYLDNEKKKIKKKNPRNLKINKIDKSLCKNIRKPKLPSSSGIVNPSRYQLIDSCHISQITNYKIQLPHNRTLSRCADAIPLIPLCNPTCSPLSHPISGLQMSFIDLLELYNVRINLIAKSLGVTMDNLRKMSTQQQISLLYCSSR 490

[Close]

BLAST of Smed-notum vs. TrEMBL
Match: T1E107 (Notum OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 750.74 bits (1937), Expect = 0.000e+0
Identity = 372/496 (75.00%), Postives = 433/496 (87.30%), Query Frame = 1

Query:  208 IFDRINKLNDPQSSNSIHSRKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTG-KSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKMNTQQQISLLYCSSR 1692
            +FD ++KLN  Q+ NS H R+YQ+FQLKKFPNSTNVRCNDGSIPGYYTR S + CS+KWLIFLEGGWYCF++NTC+SR+RTHYDLFSSEFWSSERQLGGILSNNERINP F+D+N+VYIPYCSSDLWSGK+ +KT GLYFHGSRILD V+DDL++N  FKK   V FVGSSAGGIGVLLNIDR+ RR+KK  +RK+ ++GIVDSAWFLDYPAYRQSNCTHIY+CPPE A++ GM LW+PRIPRRCK+FQG  ++W+CFMG VIYRHLKNP FIIQSLFDDAQLQMSKVPILEGGSN+KFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAY+SVNNQ LH+TL YW+  L  + K+ K+K+ +  K+++ G  +  KNL + K   +    ++QLIDSCHISQ+T+   +L  NRTL+RCA+AIPLIPLCNP+C+PLSHP+SGL MSFIDLLELYNVRINLIAKSLG +M+ LRKMNTQQQISLLYCSSR
Sbjct:   37 VFDTLSKLNGQQTQNSFHGRRYQHFQLKKFPNSTNVRCNDGSIPGYYTRLSQSKCSRKWLIFLEGGWYCFDDNTCQSRKRTHYDLFSSEFWSSERQLGGILSNNERINPGFYDFNAVYIPYCSSDLWSGKRWKKTKGLYFHGSRILDAVIDDLSKNNRFKKAKSVDFVGSSAGGIGVLLNIDRIARRIKKSFRRKIPVNGIVDSAWFLDYPAYRQSNCTHIYDCPPETAIQKGMSLWSPRIPRRCKRFQGPNKQWRCFMGHVIYRHLKNPVFIIQSLFDDAQLQMSKVPILEGGSNQKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYLSVNNQGLHQTLAYWKLSLANKFKRSKQKLPRGRKIVQKGCPNSDKNLPQMK---DPSPRQFQLIDSCHISQVTNSNNRLFLNRTLTRCADAIPLIPLCNPSCTPLSHPVSGLKMSFIDLLELYNVRINLIAKSLGTTMDGLRKMNTQQQISLLYCSSR 529

[Close]

BLAST of Smed-notum vs. TrEMBL
Match: A0A5K3FN45 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 390.963 bits (1003), Expect = 1.085e-124
Identity = 192/351 (54.70%), Postives = 247/351 (70.37%), Query Frame = 1

Query:  265 RKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXX-----------XXXXXXXXXVFIHGIVDSAWFLDYPAYRQ---SNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYL 1275
            R Y+ F L  F    +VRCNDG+  GYY R S    S+KW+I+LEGGWYCF+  TC SR+ T++ LFSS  W   R +GG+LS +ERINPN+HDYN++++PYCSSDLWSGK+ E T G YFHGSRIL  VVDDL Q   F +  +V FVGSSAGGIGV+LNIDRL R           +L +++   + I G+VDSAWFL+YP Y Q   S+CT IY+CPPE  +  G+ LW PRIPRRC+  QG+   W+C++GPVIY +++ P FIIQSLFD+AQLQMS+  +L GG   K +YIQ LG   A++L   +GVFA +C DHEILT ++WA + VN+Q L +TLN W A+L
Sbjct:   68 RNYKVFHLI-FLRQLDVRCNDGTRAGYYIRRSKNTNSRKWMIYLEGGWYCFDEATCISRQITNHALFSSRTWHINRYIGGVLSWDERINPNYHDYNTIFVPYCSSDLWSGKKSEPTGGYYFHGSRILTAVVDDLLQRPEFSQAEKVVFVGSSAGGIGVMLNIDRLARRIRRGLRYRRWQLTRRIATNIQISGLVDSAWFLNYPTYAQPFSSSCTSIYDCPPEEGILRGIGLWQPRIPRRCRVAQGKKNFWQCYLGPVIYSYIQTPIFIIQSLFDEAQLQMSRALLLTGGPYNKLAYIQNLGKAVAKSLDTVRGVFAPACSDHEILTTNHWAQLMVNSQSLQDTLNAWDAHL 417

[Close]

BLAST of Smed-notum vs. TrEMBL
Match: A0A0R3WAH5 (Uncharacterized protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS7553 PE=4 SV=1)

HSP 1 Score: 384.415 bits (986), Expect = 5.442e-122
Identity = 187/351 (53.28%), Postives = 251/351 (71.51%), Query Frame = 1

Query:  265 RKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVF-----------IHGIVDSAWFLDYPAYRQS---NCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYL 1275
            R ++ FQL+ F   ++VRCNDG+  GYY R S    S+ W+I+LEGGWYCF+  TC SR+ T++ LFSS  W   R +GG+LS ++RINPN+H+YN++++PYCSSDLW+GK+ E+T G YFHGSRIL  V+DDL +   F     V F GSSAGGIGV+LNIDRL RRL++ L+ + +           I G+VDSAWFL++P Y Q+   +CT IY+CPPE  +  G+ LW PRIPRRC+  QG+   W+C++GPVIY H++ PTFIIQSLFD+AQLQMS+  +L GG   K +YIQ LG   A++L   +GVFA +C DHEILT ++WA + V++Q LH+TLN W A+L
Sbjct:   66 RNHKVFQLR-FLIQSDVRCNDGTRAGYYVRRSKDVKSRNWMIYLEGGWYCFDEATCISRQITNHALFSSRTWHMIRYIGGVLSWDDRINPNYHNYNTIFVPYCSSDLWTGKKRERTGGYYFHGSRILTAVIDDLLRQPEFTGADRVVFAGSSAGGIGVMLNIDRLARRLRRGLRYRRWQQSTRNYGRLQISGLVDSAWFLNHPTYAQAYSGSCTSIYDCPPEEGILRGIGLWQPRIPRRCRMAQGKKNFWQCYLGPVIYPHIRTPTFIIQSLFDEAQLQMSRAILLTGGPYNKLAYIQNLGKAVAKSLDTVQGVFAPACTDHEILTTNHWAQLMVDSQSLHDTLNAWDAHL 415

[Close]

BLAST of Smed-notum vs. TrEMBL
Match: A0A068Y747 (Protein notum OS=Echinococcus multilocularis OX=6211 PE=4 SV=1)

HSP 1 Score: 367.466 bits (942), Expect = 4.159e-114
Identity = 174/325 (53.54%), Postives = 229/325 (70.46%), Query Frame = 1

Query:  343 YYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNID-----------XXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQS---NCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYL 1275
            YY R S    S+ WLI+LEGGWYCF+  TC SR+ T++ LFSS  W   R +GG+LS ++RINPN+H+YN++++PYCSSDLW+GK+ E+T G YFHGSRIL  V+DDL +   F +V +V F GSSAGGIGV+LNID             + R   +   ++ I G+VDSAWFL YP Y Q+   +CT IY+CPPE  +  G+ LW PRIPRRC+  QG+   W+C++GPVIY HL+ PTFIIQSLFD+AQLQMS+  +L GGS  K +YIQ LG   A++L   +GVFA +C DHEILT ++WA + V++Q LH+TL  W A+L
Sbjct:  197 YYVRRSKDLKSRNWLIYLEGGWYCFDEATCISRQITNHALFSSRTWHMIRYIGGVLSWDDRINPNYHNYNTIFVPYCSSDLWTGKKRERTGGYYFHGSRILTAVIDDLLRQPEFIRVDKVVFSGSSAGGIGVMLNIDRLARRLRRGLRYRRWRQSTRNYSRLQISGLVDSAWFLHYPTYAQAYSGSCTSIYDCPPEEGILRGIGLWQPRIPRRCRMAQGKKNFWQCYLGPVIYSHLRTPTFIIQSLFDEAQLQMSRAILLTGGSYNKLAYIQNLGKAVAKSLDTVQGVFAPACTDHEILTTNHWAQLMVDSQSLHDTLKAWDAHL 521

HSP 2 Score: 60.8474 bits (146), Expect = 7.468e-6
Identity = 25/68 (36.76%), Postives = 42/68 (61.76%), Query Frame = 1

Query: 1480 CANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKMNTQQQISLLYC 1683
            CA    + PLCNP+C  L+HP +   +S + L ELY V    +A ++G+S+ QL+ +  + Q+ +L+C
Sbjct:  647 CAGRSHMTPLCNPSCRTLTHPHTMERLSVVSLYELYGVDSAQLAANIGVSVTQLKALPVKMQMQMLFC 714

[Close]

BLAST of Smed-notum vs. Ensembl Cavefish
Match: notum1a (notum, palmitoleoyl-protein carboxylesterase [Source:NCBI gene;Acc:103027144])

HSP 1 Score: 241.506 bits (615), Expect = 6.736e-72
Identity = 155/479 (32.36%), Postives = 223/479 (46.56%), Query Frame = 1

Query:  232 NDPQSSNSIHSRKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLY-FHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKV-----PILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKM 1650
            N  QS     ++K  Y     F  + +V CNDG+  GYY + S    S++WLIFLEGGWYCFN   C+SR  T   L SS  W   +   GILS+    NP++ + N V++PYCSSD+WSG   +     Y F GS I+  VV DL  ++       +   GSSAGG GVLLN+D +   L++     + + G+ DS WFLD   YR + C     C P  A++ G+K W   +P RC++   +  +WKCF G  +Y  ++ P F++Q LFD+AQL +  +     P+ EG    ++ YIQ LG     TL+    +FA +C+ HE++T++ W  + V    L   L+ W   L                         KN +     G        LIDSC            PH                CNPTC  +    +G  M+ I  L      +  +A+  G+   +L  M
Sbjct:   81 NLAQSLYPCSAQKLDYDMKLHFVENASVTCNDGTPAGYYLKESRG--SRRWLIFLEGGWYCFNKENCDSRYETMRRLMSSSKWPQTKTGTGILSSLPEENPHWWNANMVFLPYCSSDVWSGATPKTDQNDYAFMGSLIIKEVVKDLL-SKGLDNGKILLLAGSSAGGTGVLLNVDAVAELLEQLGHPNIQVRGLSDSGWFLDNNQYRSTVCVDTISCAPTEAIKRGIKYWGGVVPERCRQ-ANKESDWKCFFGYQVYPTIRRPVFVVQWLFDEAQLTVDNIHLTGQPVQEG----QWRYIQNLGIELRNTLKDVPALFAPACLSHEVITRNYWIDIQVKGTSLPRALHCWDRSLHDNN---------------------KNNKTTHHKG----CPMHLIDSC----------PWPH----------------CNPTCPTIRDQATGQEMNVIQFLMHMGFDVQKMAQQQGMDPSKLLGM 500

[Close]

BLAST of Smed-notum vs. Ensembl Cavefish
Match: notum2 (carboxylesterase notum2-like [Source:NCBI gene;Acc:103040225])

HSP 1 Score: 236.498 bits (602), Expect = 3.154e-70
Identity = 130/334 (38.92%), Postives = 190/334 (56.89%), Query Frame = 1

Query:  307 TNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSG-------KQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPILEGG---SNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLE 1278
            T   CNDG+  G+Y +      SK+WLIFLEGGW C+N +TC+SR +    L SS  W   R+  GILS     NP++++ N V++PYCSSD+WSG       KQ ++T    F GS I+  V+ DL  ++  K+   V   G+SAGG GVLLNI+       ++L     + G+VDS WFL+    + S+C     C P +A++ G++LWN  IP +CK+   RG EW+CF G  ++  L  P F++Q LFD+ QL++  + +  GG   S ++++Y+Q LG     +L+    VFA SC+ H ++TKSNW    V    L   L  W   L+
Sbjct:   82 TPAICNDGTAAGFYLK--EFKGSKRWLIFLEGGWCCYNKDTCDSRYKNIPRLMSSSDWPQTRKGSGILSAQADENPHWYNANIVFVPYCSSDVWSGNKPAVKAKQGKETE-YSFVGSVIIREVIKDLA-SKGIKQAKVVMLAGTSAGGTGVLLNIE-KVASQLEQLGADTQVRGLVDSGWFLE-SKQKASDCPDSVSCTPVDAIKKGIRLWNGVIPEKCKQHYKRGEEWQCFFGHKLFSFLSTPLFVVQWLFDEEQLRVENIYL--GGQSLSEQQWTYMQNLGKELKNSLKDVTAVFAPSCLSHTLITKSNWMDFQVKGTSLSRALQCWDRSLQ 407

[Close]

Query:  307 TNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSG-------KQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPILEGG---SNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLE 1278
            T   CNDG+  G+Y +      SK+WLIFLEGGW C+N +TC+SR +    L SS  W   R+  GILS     NP++++ N V++PYCSSD+WSG       KQ ++T    F GS I+  V+ DL  ++  K+   V   G+SAGG GVLLNI+       ++L     + G+VDS WFL+    + S+C     C P +A++ G++LWN  IP +CK+   RG EW+CF G  ++  L  P F++Q LFD+ QL++  + +  GG   S ++++Y+Q LG     +L+    VFA SC+ H ++TKSNW    V    L   L  W   L+
Sbjct:   82 TPAICNDGTAAGFYLK--EFKGSKRWLIFLEGGWCCYNKDTCDSRYKNIPRLMSSSDWPQTRKGSGILSAQADENPHWYNANIVFVPYCSSDVWSGNKPAVKAKQGKETE-YSFVGSVIIREVIKDLA-SKGIKQAKVVMLAGTSAGGTGVLLNIE-KVASQLEQLGADTQVRGLVDSGWFLE-SKQKASDCPDSVSCTPVDAIKKGIRLWNGVIPEKCKQHYKRGEEWQCFFGHKLFSFLSTPLFVVQWLFDEEQLRVENIYL--GGQSLSEQQWTYMQNLGKELKNSLKDVTAVFAPSCLSHTLITKSNWMDFQVKGTSLSRALQCWDRSLQ 407

[Close]

BLAST of Smed-notum vs. Ensembl Cavefish
Match: notum1a (notum, palmitoleoyl-protein carboxylesterase [Source:NCBI gene;Acc:103027144])

HSP 1 Score: 213.386 bits (542), Expect = 1.733e-61
Identity = 149/479 (31.11%), Postives = 210/479 (43.84%), Query Frame = 1

Query:  232 NDPQSSNSIHSRKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLY-FHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKV-----PILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKM 1650
            N  QS     ++K  Y     F  + +V CNDG+  GYY + S    S++WLIFLEGGWYCFN   C+SR  T   L SS  W   +   GILS+    NP++ + N V++PYCSSD+WSG   +     Y F GS I+  VV DL  ++       +   GSSAGG GVLLN+D +   L++     + + G+ DS WFLD   YR + C     C P  A++ G+K W   +P RC++   +  +WKCF G  +Y  ++ P F++Q LFD+AQL +  +     P+ EG    ++ YIQ LG     TL+                    W  + V    L   L+ W   L                         KN +     G        LIDSC            PH                CNPTC  +    +G  M+ I  L      +  +A+  G+   +L  M
Sbjct:   81 NLAQSLYPCSAQKLDYDMKLHFVENASVTCNDGTPAGYYLKESRG--SRRWLIFLEGGWYCFNKENCDSRYETMRRLMSSSKWPQTKTGTGILSSLPEENPHWWNANMVFLPYCSSDVWSGATPKTDQNDYAFMGSLIIKEVVKDLL-SKGLDNGKILLLAGSSAGGTGVLLNVDAVAELLEQLGHPNIQVRGLSDSGWFLDNNQYRSTVCVDTISCAPTEAIKRGIKYWGGVVPERCRQ-ANKESDWKCFFGYQVYPTIRRPVFVVQWLFDEAQLTVDNIHLTGQPVQEG----QWRYIQNLGIELRNTLKDVP----------------YWIDIQVKGTSLPRALHCWDRSLHDNN---------------------KNNKTTHHKG----CPMHLIDSC----------PWPH----------------CNPTCPTIRDQATGQEMNVIQFLMHMGFDVQKMAQQQGMDPSKLLGM 484

[Close]

BLAST of Smed-notum vs. Ensembl Cavefish
Match: ENSAMXT00000021130.2 (pep primary_assembly:Astyanax_mexicanus-2.0:5:28109530:28127000:-1 gene:ENSAMXG00000020491.2 transcript:ENSAMXT00000021130.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 206.838 bits (525), Expect = 3.033e-59
Identity = 147/464 (31.68%), Postives = 211/464 (45.47%), Query Frame = 1

Query:  265 RKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLY-FHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPIL-EGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKM 1650
            R  Q  +L+   NST V CNDGS  GYY R S    S++WL+FLEG            + RT         W +     GILS     NP++ + N V+IPYCSSD+WSG   +     Y F GS I+  V+ +L   +       +   GSSAGG GVLLN+DR+   LK +    + + G+ DS WFLD   YR ++C     C P  A++ G++ W   +P RC +    G EW CF G  +Y  LK+P F++Q LFD+AQL +  V ++ +     ++ YIQ LG     TL+    +FA +C+ HE++T+S W  + V    L   L  W   L            +N     + +SP +                 LIDSC            PH                CNPTC  +   ++G  M+ I  L      +  +A+  G+   +L  M
Sbjct:   78 RLDQDMKLRFLENST-VTCNDGSPAGYYIRESKG--SRRWLVFLEG------------KYRT--------LWCT-----GILSPQPEENPHWWNANMVFIPYCSSDVWSGATPKTDQNDYAFMGSLIIQEVIKELL-TKGLDNAKVLLLAGSSAGGTGVLLNVDRVAELLKSRGHGSIQVRGLADSGWFLDNEQYRCTDCVDTMSCAPTEAIKRGIRYWGGVVPERC-RLAHTGAEWNCFFGYKVYPTLKSPVFVVQWLFDEAQLTVDNVHLMGQPVQEDQWRYIQNLGIDLRNTLKNVPAMFAPACLSHEVITRSYWMDIQVKGTSLPRALQCWDRSLH--------HSLRNHGNSSSPRSPPRG------------CPLHLIDSC----------PWPH----------------CNPTCPAIRDQLTGREMNVIQFLTHMGFDVQRMAQQQGLDPNKLLGM 465

[Close]

BLAST of Smed-notum vs. Ensembl Nematostella
Match: EDO46655 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPB3])

HSP 1 Score: 197.978 bits (502), Expect = 4.282e-57
Identity = 117/337 (34.72%), Postives = 174/337 (51.63%), Query Frame = 1

Query:  280 FQLK-KFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYD-LFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNG--LYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPILEGGSN---KKFSYIQQLGGFAAQTLRQA--KGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYW 1263
            F LK  +    N  CNDGS  GYY + S    SK+WL++LEGGW+C+N  +C  R  +    L +S+ WS  ++  G+LS     NPN+ + N V IPYCSSD WSG       G    F G+RIL+ V++DL     +   H +   GSSAGGIGV+LN+D         +   V + G+ DS W+L    +  S    + EC P   ++ GM  W   +P  C K +   + W C+ G  +Y  +  P FI Q L+D+AQL +       G      K+   I ++G    ++L++A  + VF+ +C+ H ILT S+W  + +    L++ L  W
Sbjct:   27 FDLKLHYLTDVNTTCNDGSPAGYYLKESPK--SKRWLVYLEGGWFCYNQMSCNIRANSQMRYLMTSKNWSKTKRGNGMLSPQPEENPNWWNANHVLIPYCSSDAWSGNASRHETGEKFSFLGARILEKVIEDLLPRGLYNAKH-LLLAGSSAGGIGVILNLD-RISTKLHAMGFAVEVRGLADSGWYLSDRPFESSCPPGVKECGPVKTIKEGMMYWRGIVPENCTK-ENLLQPWMCYFGETVYPTITAPLFIFQWLYDEAQLALDGSIQPRGIQTIDLKQIKTIFKIGRKIRESLKRARVRHVFSPACISHTILTHSSWLNIRLKGASLNDILTCW 358

[Close]

BLAST of Smed-notum vs. Ensembl Nematostella
Match: EDO39429 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SA46])

HSP 1 Score: 130.954 bits (328), Expect = 2.017e-33
Identity = 93/342 (27.19%), Postives = 158/342 (46.20%), Query Frame = 1

Query:  313 VRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLE----KTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYR-----QSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQL-QMSKVPILEGGSNKKFSYIQQLGGFAAQTLRQAK--------GVFAHSCVDH-EILTKSNWAYVSVNNQRLHETLNYWQAYLEG 1281
             +C DGS+P Y+ R      + KW+++L+GG +C +   C  R +T  +L SS  +      GGILS+    N +FH +N VY+PYC    ++G + +    K   LY  G RIL  ++DDL   +  +   +V F G+SAG + VL+N D +K+RL         +  + DS  FL+ P  +       +   +YE      L +     NP    +C + +     W+C       R ++ P +++  L+D  QL  +  V  +    +     ++ +  F  +TL   +         VF   C+DH +++    W  + VN Q +HE  + W   ++G
Sbjct:    7 AKCLDGSLPAYFYRRGHGAGTHKWILYLQGGAWCDSAENCYHRSKT--NLGSSRNYKHLMDAGGILSDKMHENKHFHSWNVVYVPYCDGASFTGNRSDPVVVKGQRLYMRGKRILSALIDDLLV-KGLQNATDVVFTGTSAGALAVLMNADYVKQRLPASTS----MVALSDSGVFLNEPDLKGVKKFGKSMKRVYE------LHDSADSINP----KCARKKAAKDRWECMFPAEFVRSIETPVYMVNPLYDAWQLANVVGVRCVYSPESCDKHEMKVIREFRKKTLNALEPILRNKNHKVFGDGCIDHGQVIFDKKWNEIKVNKQAMHEAFHEWHQDVKG 331

[Close]

BLAST of Smed-notum vs. Ensembl Nematostella
Match: EDO47398 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLV4])

HSP 1 Score: 125.176 bits (313), Expect = 3.196e-31
Identity = 99/361 (27.42%), Postives = 162/361 (44.88%), Query Frame = 1

Query:  262 SRKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSE-RQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLE----KTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPR--IPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPILEGG--------------SNKKFSYIQQLGGFAAQTLR-----QAKGVFAHSCVDH-EILTKSNWAYVSVNNQRLHETLNYW 1263
            SR  Q   LK       V C DGS PGYY R  +   S  W++   GG +C++   C  R +T   L SS+++     +L G+LS + RINP+FHD+N V I YC    ++G + E    +   +Y  G RIL+ ++D L  +Q F K   V   G+SAGG+ V+L+ D     ++ KL + + +  + DS +F+D  +    N  + +        +   ++ N    + + C +    G +WKC      +R L  P FI+QS +D  Q+   + P                   ++++   I Q        L      +  G+   SC++H + L    W  + VN   + E +  W
Sbjct:   11 SRDVQLILLKSAVKQGAV-CLDGSPPGYYYREGSGKGSDNWVLHFFGGAWCYDEEACLQRSKT--VLGSSKYFPEHPPKLQGVLSGDARINPDFHDWNLVMICYCDGASFTGYRTEPVSIRGELIYMRGKRILEAIMDQLLSSQ-FSKAKRVLLTGTSAGGLSVVLHAD----YIRNKLPKSMALRAMSDSGYFVDIASLNGGNIINRH-------FKRMFEVHNSTAGVQQDCVRDAEPGYQWKCLFPQHTFRFLSTPIFILQSAYDAWQIIHVRGPHPSWAYRHIHGIYCKPPECTSRELKAIMQYRNITLHALHPVLRSRTSGLLLTSCMEHSQSLYDDTWTKLYVNGLPVSEIVGDW 356

[Close]

BLAST of Smed-notum vs. Ensembl Nematostella
Match: EDO38898 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBM6])

HSP 1 Score: 80.4925 bits (197), Expect = 4.352e-16
Identity = 62/210 (29.52%), Postives = 102/210 (48.57%), Query Frame = 1

Query:  241 QSSNSIHSRKYQYFQLKKF----PNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTN--GLYFHGSRILDTVVDDLTQNQHFKKVHEVA-FVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAW-FLDYPAY 846
            + + S+  RK   + L+K         N  C DGS   +Y   S    SK W+I L+ G  C ++ TC  R +  +   SS+ +        + S+N   NP F  +N V +PYCS D++ G++ ++T+  GL   G  I+  VV  L  +        V  F G+SAGG+G+L N+D   +++    K  +F+H +  + + +L  P Y
Sbjct:   50 RKTRSVRPRKKYRYNLRKHEIRDARDRNALCLDGSPAVFYL--SRNPYSKDWVIQLQAGGSCGDHKTCHERAKGSFG--SSKDYELYMTGSFLSSDNPNENPTFASWNKVLVPYCSGDVFVGRKTKETHPYGLQMLGHFIVKAVVQQLMDDYKINTTGTVILFGGASAGGLGMLANVD-FVQQMVLPAKVHLFLHVVCSAVFKYLSTPIY 254

[Close]

BLAST of Smed-notum vs. Ensembl Medaka
Match: notum1a (notum, palmitoleoyl-protein carboxylesterase [Source:NCBI gene;Acc:101171916])

HSP 1 Score: 244.973 bits (624), Expect = 2.309e-73
Identity = 152/458 (33.19%), Postives = 215/458 (46.94%), Query Frame = 1

Query:  295 FPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLY-FHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQL-----QMSKVPILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKM 1650
            F  +T+V CNDGS  GYY + S    S++WLIFLEGGWYCFN   C++R  T     SS  W   +   GILS     NP++ + N V+IPYCSSD+WSG   +     Y F GS I+  VV DL  N+       +   GSSAGG GVLLN+D +   L+      + + G+ DS WFLD   Y+ ++C     C P   ++ G K W   +P RC++    G EW CF G  ++  +K+P F++Q LFD+AQL     Q++  P+ EG    ++ YIQ LG     TL+    +FA +C+ HE++T++ W  V V    L   L+ W   L+                 +  K+P K                 LIDSC            PH                CNPTC  +    +G  M+    L      +  +A+  G+   +L  M
Sbjct:   95 FLKNTSVTCNDGSPAGYYLKESRG--SRRWLIFLEGGWYCFNKENCDTRYETMRRFMSSSKWPHTKTGTGILSPLPEENPHWWNANMVFIPYCSSDVWSGATAKTEQNFYAFMGSLIIQEVVKDLL-NKGLDNAKVLLLAGSSAGGTGVLLNVDGVAELLEGLGHTGIQVRGLSDSGWFLDNKQYQCTDCGDTASCAPTETIKRGFKYWGAVVPERCRQTH-EGEEWNCFFGYRVFPSIKSPVFVVQWLFDEAQLTVDNIQLTGQPVQEG----QWRYIQNLGTELRNTLKDVPAMFAPACLSHEVITRNYWIDVQVKGTSLPRALHCWDRSLQDN---------------RNNKAPPK------------ACPVHLIDSC----------PWPH----------------CNPTCPTIRDQFTGQEMNVFQFLMHMGFDVQKMAQQQGMDPSKLLGM 491

[Close]

BLAST of Smed-notum vs. Ensembl Medaka
Match: notum2 (carboxylesterase notum2 [Source:NCBI gene;Acc:101157515])

HSP 1 Score: 239.965 bits (611), Expect = 2.963e-71
Identity = 126/349 (36.10%), Postives = 194/349 (55.59%), Query Frame = 1

Query:  295 FPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSG-------------------KQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPI-LEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEG 1281
            F  +T V CNDG+  G+Y + S  N  ++W++FLEGGW C++  +C++R +T   L SS  W   +   GILS+    NP++++ N V+IPYCSSD+W+G                   ++   T    F GS I+  V+ DL   +  K    +   G+SAGG GVLLNI+R+  +L +       + G+VDS WFL+    R +NC     C PE+A++NG++LWN  +P +C++   +G EW+CF G  +Y  L +P F++Q LFD+ QL++  + +  +  S++++ YIQ LG     +LR    VFA SC+ H ++TKS W    V    L   L+ W   LE 
Sbjct:   88 FLRNTQVTCNDGTAAGFYLKESRGN--RRWILFLEGGWCCYSKESCDARYQTVPRLMSSTVWPQIKTGTGILSSRAEENPHWYNANRVFIPYCSSDVWTGTGPAPTPPTRQRQGRDKIKERNTNTTEYSFMGSLIIREVIKDLIP-KGIKMAKVIMLAGTSAGGTGVLLNIERVASQLAQLGTD-AQVRGLVDSGWFLESKKERPTNCPETVSCSPEDAIKNGLRLWNGAVPEQCQQLYQKGEEWQCFFGHRLYSTLTSPLFVVQWLFDEEQLRVENIYMGAQSLSDEQWQYIQNLGLELKNSLRGVTAVFAPSCLSHTVITKSEWMSFQVKGTTLPRALHCWDRSLEA 432

[Close]

BLAST of Smed-notum vs. Planmine SMEST
Match: SMESG000004222.1 (SMESG000004222.1)

HSP 1 Score: 962.6 bits (2487), Expect = 0.000e+0
Identity = 496/496 (100.00%), Postives = 496/496 (100.00%), Query Frame = 1

Query:  205 LIFDRINKLNDPQSSNSIHSRKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDXXXXXXXXXXXXXVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEXXXXXXXXXXXXXXXXTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKMNTQQQISLLYCSSR 1692
            LIFDRINKLNDPQSSNSIHSRKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDRLKRRLKKKLKRKVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEKKKIKKKVQKNPKLIKTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKMNTQQQISLLYCSSR
Sbjct:   32 LIFDRINKLNDPQSSNSIHSRKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWYCFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVYIPYCSSDLWSGKQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFVGSSAGGIGVLLNIDRLKRRLKKKLKRKVFIHGIVDSAWFLDYPAYRQSNCTHIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLKNPTFIIQSLFDDAQLQMSKVPILEGGSNKKFSYIQQLGGFAAQTLRQAKGVFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEKKKIKKKVQKNPKLIKTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPHNRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIAKSLGISMEQLRKMNTQQQISLLYCSSR 527

The following BLAST results are available for this feature:

BLAST of Smed-notum vs. Ensembl Human
BLAST of Smed-notum vs. Ensembl Celegans
BLAST of Smed-notum vs. Ensembl Fly
BLAST of Smed-notum vs. Ensembl Zebrafish
BLAST of Smed-notum vs. Ensembl Xenopus
BLAST of Smed-notum vs. Ensembl Mouse
BLAST of Smed-notum vs. UniProt/SwissProt
BLAST of Smed-notum vs. TrEMBL
BLAST of Smed-notum vs. Ensembl Cavefish
BLAST of Smed-notum vs. Ensembl Sea Lamprey
BLAST of Smed-notum vs. Ensembl Yeast
BLAST of Smed-notum vs. Ensembl Nematostella
BLAST of Smed-notum vs. Ensembl Medaka
BLAST of Smed-notum vs. Planmine SMEST

BLAST of Smed-notum vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3


Match Name	E-value	Identity	Description
NOTUM	1.154e-73	34.36	notum, palmitoleoyl-protein carboxylesterase [Sour...	[more]
NOTUM	1.835e-44	43.56	notum, palmitoleoyl-protein carboxylesterase [Sour...	[more]
NOTUM	1.718e-40	40.00	notum, palmitoleoyl-protein carboxylesterase [Sour...	[more]

BLAST of Smed-notum vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Smed-notum vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
Notum	1.543e-59	36.29	gene:FBgn0044028 transcript:FBtr0075435	[more]

BLAST of Smed-notum vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
notum1a	6.196e-75	33.61	notum, palmitoleoyl-protein carboxylesterase a [So...	[more]
notum2	4.499e-70	36.97	Danio rerio notum pectinacetylesterase 2 (notum2),...	[more]
notum2	4.499e-70	36.97	Danio rerio notum pectinacetylesterase 2 (notum2),...	[more]

BLAST of Smed-notum vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
notum	2.399e-75	33.33	notum, palmitoleoyl-protein carboxylesterase [Sour...	[more]
notum	2.539e-75	33.33	notum, palmitoleoyl-protein carboxylesterase [Sour...	[more]
prdm5	3.932e-67	31.97	PR domain 5 [Source:Xenbase;Acc:XB-GENE-854777]	[more]
notum	2.265e-65	32.22	notum, palmitoleoyl-protein carboxylesterase [Sour...	[more]
notum	1.363e-57	29.84	notum, palmitoleoyl-protein carboxylesterase [Sour...	[more]

BLAST of Smed-notum vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3


Match Name	E-value	Identity	Description
Notum	2.306e-75	34.14	notum palmitoleoyl-protein carboxylesterase [Sourc...	[more]
Notum	2.306e-75	34.14	notum palmitoleoyl-protein carboxylesterase [Sourc...	[more]
Notum	1.095e-25	49.12	notum palmitoleoyl-protein carboxylesterase [Sourc...	[more]

BLAST of Smed-notum vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|F8U830\|NOTUM_SCHMD	0.000e+0	100.00	Palmitoleoyl-protein carboxylesterase NOTUM OS=Sch...	[more]
sp\|A0A0D3QS97\|NOTU2_XENLA	2.796e-77	34.50	Palmitoleoyl-protein carboxylesterase notum2 OS=Xe...	[more]
sp\|Q8R116\|NOTUM_MOUSE	1.613e-74	34.14	Palmitoleoyl-protein carboxylesterase NOTUM OS=Mus...	[more]
sp\|A0A0D3QS99\|NOT1_XENLA	4.331e-74	33.11	Palmitoleoyl-protein carboxylesterase notum1 OS=Xe...	[more]
sp\|C5H5C4\|NOT1A_DANRE	4.677e-74	33.61	Palmitoleoyl-protein carboxylesterase notum1a OS=D...	[more]

BLAST of Smed-notum vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A481SAC8	0.000e+0	88.78	Notum (Fragment) OS=Dugesia japonica OX=6161 PE=2 ...	[more]
T1E107	0.000e+0	75.00	Notum OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1	[more]
A0A5K3FN45	1.085e-124	54.70	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
A0A0R3WAH5	5.442e-122	53.28	Uncharacterized protein OS=Taenia asiatica OX=6051...	[more]
A0A068Y747	4.159e-114	53.54	Protein notum OS=Echinococcus multilocularis OX=62...	[more]

BLAST of Smed-notum vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
notum1a	6.736e-72	32.36	notum, palmitoleoyl-protein carboxylesterase [Sour...	[more]
notum2	3.154e-70	38.92	carboxylesterase notum2-like [Source:NCBI gene;Acc...	[more]
notum2	3.154e-70	38.92	carboxylesterase notum2-like [Source:NCBI gene;Acc...	[more]
notum1a	1.733e-61	31.11	notum, palmitoleoyl-protein carboxylesterase [Sour...	[more]
ENSAMXT00000021130.2	3.033e-59	31.68	pep primary_assembly:Astyanax_mexicanus-2.0:5:2810...	[more]

BLAST of Smed-notum vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Smed-notum vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Smed-notum vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4


Match Name	E-value	Identity	Description
EDO46655	4.282e-57	34.72	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39429	2.017e-33	27.19	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47398	3.196e-31	27.42	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38898	4.352e-16	29.52	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Smed-notum vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2


Match Name	E-value	Identity	Description
notum1a	2.309e-73	33.19	notum, palmitoleoyl-protein carboxylesterase [Sour...	[more]
notum2	2.963e-71	36.10	carboxylesterase notum2 [Source:NCBI gene;Acc:1011...	[more]

BLAST of Smed-notum vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000004222.1	0.000e+0	100.00	SMESG000004222.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30010051
GenBank	F8U830

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30010051 ID=SMED30010051|Name=Smed-notum|organism=Schmidtea mediterranea sexual|type=transcript|length=1917bp
TATAAATATCGACGATCACATAACTAACCAAAGTTAAATCTAAAATTTCT
GAGGATCGAAAAAATTGAAAACTATTCTTCAAATATTTGGTTTTTATTCC
AGGATCAAAAAATGAAATCATATCTGATATTGAATACTCTTCTATTGAGC
CTATTGAAGATCAATGGATTTTCCAAATCGTCTTGGTTCAGTTCAAAGAC
TTCGTTGATTTTCGATCGAATCAACAAATTGAATGATCCGCAATCCAGTA
ATTCAATTCACAGTAGAAAATATCAGTATTTTCAGTTGAAAAAATTTCCA
AATTCTACAAACGTTCGCTGCAATGACGGAAGCATTCCAGGTTATTACAC
CCGCCCATCGACAACAAATTGTTCAAAAAAATGGCTCATCTTTTTAGAAG
GAGGATGGTATTGTTTTAACAACAATACTTGTGAATCCCGTAGACGAACT
CATTATGATTTATTTTCATCAGAATTTTGGTCTTCTGAACGGCAACTTGG
AGGAATTCTTTCTAATAATGAGCGAATCAATCCAAATTTTCATGACTATA
ATTCAGTGTATATTCCTTACTGTTCGAGTGATTTGTGGTCTGGCAAACAA
TTAGAAAAAACTAATGGATTATATTTCCATGGATCTCGAATTTTAGACAC
AGTCGTTGATGATTTGACCCAAAACCAGCATTTTAAAAAGGTTCATGAAG
TAGCTTTTGTTGGATCGAGCGCTGGTGGAATCGGAGTTTTGTTGAATATC
GATAGGCTGAAAAGACGATTGAAGAAAAAACTTAAACGAAAAGTATTTAT
TCATGGAATAGTCGATTCAGCGTGGTTTCTCGATTATCCGGCGTATAGAC
AGTCAAACTGTACCCATATTTACGAATGCCCTCCAGAAAATGCCCTTAGA
AATGGAATGAAATTATGGAATCCTCGAATTCCGAGAAGATGCAAGAAATT
CCAAGGTCGCGGTAGGGAATGGAAATGTTTCATGGGTCCTGTCATATATA
GGCACTTGAAAAATCCAACTTTCATTATACAAAGTCTATTTGATGACGCT
CAACTGCAGATGTCAAAAGTCCCGATTTTAGAAGGAGGATCTAACAAAAA
GTTTTCATACATTCAACAATTAGGAGGTTTTGCAGCTCAGACTTTGAGGC
AGGCAAAAGGAGTATTCGCTCATTCTTGTGTTGATCATGAAATTTTAACA
AAAAGTAATTGGGCTTATGTTAGTGTCAACAATCAACGACTCCACGAAAC
GCTAAATTATTGGCAAGCATATTTAGAAGGTGAAAAGAAAAAAATAAAGA
AAAAAGTCCAAAAAAATCCGAAACTTATCAAAACCGGCAAGTCTCCATGT
AAAAACTTGAGAAAGCCCAAGTTTTCTGGAAACATTGATCAAAGTAAATA
CCAATTGATTGACTCTTGCCACATTAGTCAAATTACGAGCTACAAAATAC
AGTTACCCCATAATCGAACTTTATCAAGATGTGCTAATGCCATTCCTTTG
ATTCCTTTATGCAATCCAACATGTTCACCGCTTTCCCACCCGATATCTGG
TCTCAGTATGTCCTTCATTGATCTACTGGAATTGTATAACGTTCGCATAA
ACTTAATTGCGAAATCGTTGGGTATCTCAATGGAACAATTGCGAAAAATG
AACACTCAACAACAAATAAGTTTACTTTATTGTAGCAGTCGATAAATTTT
GTTTGGTTAACGAAACCTATTCTTATCTCAGACCTACCTCTAATAATTGA
TGATTTTTTATGGCACATCTCACTCAATTTAATCCATCGATCTAGCTCTA
ATTCAAGATTTTAGATGGTTTTTTATGTTATGCATTTAACAATATTTTTG
TTATCTTTTCTGTTTTTAGTTGACTCTAGAATTGAATTTGAAAATTATTC
TTTACTCATGATACTAC

protein sequence of SMED30010051-orf-1

>SMED30010051-orf-1 ID=SMED30010051-orf-1|Name=SMED30010051-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=528bp
MKSYLILNTLLLSLLKINGFSKSSWFSSKTSLIFDRINKLNDPQSSNSIH
SRKYQYFQLKKFPNSTNVRCNDGSIPGYYTRPSTTNCSKKWLIFLEGGWY
CFNNNTCESRRRTHYDLFSSEFWSSERQLGGILSNNERINPNFHDYNSVY
IPYCSSDLWSGKQLEKTNGLYFHGSRILDTVVDDLTQNQHFKKVHEVAFV
GSSAGGIGVLLNIDRLKRRLKKKLKRKVFIHGIVDSAWFLDYPAYRQSNC
THIYECPPENALRNGMKLWNPRIPRRCKKFQGRGREWKCFMGPVIYRHLK
NPTFIIQSLFDDAQLQMSKVPILEGGSNKKFSYIQQLGGFAAQTLRQAKG
VFAHSCVDHEILTKSNWAYVSVNNQRLHETLNYWQAYLEGEKKKIKKKVQ
KNPKLIKTGKSPCKNLRKPKFSGNIDQSKYQLIDSCHISQITSYKIQLPH
NRTLSRCANAIPLIPLCNPTCSPLSHPISGLSMSFIDLLELYNVRINLIA
KSLGISMEQLRKMNTQQQISLLYCSSR*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000028	Category 2 cell
PLANA:0000101	muscle cell
PLANA:0000103	central nervous system
PLANA:0000140	anterior region of the whole animal
PLANA:0000418	head
PLANA:0002089	reproductive organ
PLANA:0003109	anterior pole cell
PLANA:0007524	anterior pole

Vocabulary: **INTERPRO**
Term	Definition
IPR004963	PAE/NOTUM

Vocabulary: **molecular function**
Term	Definition
GO:0016787	hydrolase activity
GO:0052689	carboxylic ester hydrolase activity
GO:1990699	palmitoleyl hydrolase activity

Vocabulary: **cellular component**
Term	Definition
GO:0005576	extracellular region

Vocabulary: **biological process**
Term	Definition
GO:0016055	Wnt signaling pathway
GO:0030178	negative regulation of Wnt signaling pathway
GO:1990697	protein depalmitoleylation

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR004963	Pectinacetylesterase/NOTUM	PFAM	PF03283	PAE	coord: 65..385 e-value: 1.8E-66 score: 224.7
IPR004963	Pectinacetylesterase/NOTUM	PANTHER	PTHR21562	NOTUM-RELATED	coord: 44..405
None	No IPR available	PANTHER	PTHR21562:SF45	PALMITOLEOYL-PROTEIN CARBOXYLESTERASE NOTUM	coord: 44..405
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..19 score: 0.569

Main menu

Smed-notum

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 27

Owlery

blazegraph-runner