SMED30010046

Overview


Name	SMED30010046
Smed ID	SMED30010046
Length (bp)	304

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30010046

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 31

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Lifecycle
head region	SMED30010046	h1SMcG0006787	SmedASXL_061618	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
Smed sexual biotype	SMED30010046	h1SMcG0006787	Contig31297	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010046	h1SMcG0006787	Contig31297	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010046	h1SMcG0006787	Contig32555	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010046	h1SMcG0006787	Contig32555	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30010046	h1SMcG0006787	dd_Smed_v4_1693_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30010046	h1SMcG0006787	dd_Smed_v4_1693_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30010046	h1SMcG0006787	dd_Smed_v4_1693_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010046	h1SMcG0006787	Contig563	GPL15192	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30010046	h1SMcG0006787	dd_Smed_v4_3684_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30010046	h1SMcG0006787	dd_Smed_v4_3684_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30010046	h1SMcG0006787	dd_Smed_v4_2265_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30010046	h1SMcG0006787	dd_Smed_v4_2265_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30010046	h1SMcG0006787	dd_Smed_v4_2265_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30010046	h1SMcG0006787	dd_Smed_v4_2265_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30010046	h1SMcG0006787	dd_Smed_v4_2265_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010046	h1SMcG0019490	Contig563	GPL15192	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010046	h1SMcG0006787	Contig38791	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010046	h1SMcG0006787	Contig38791	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010046	h1SMcG0006787	Contig39149	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010046	h1SMcG0006787	Contig39149	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010046	h1SMcG0006788	Contig39149	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30010046	h1SMcG0006788	Contig39149	newmark_ests	PMID:29674431 Fincher et al., 2018
head region	SMED30010046	h1SMcG0006787	dd_Smed_v6_1693_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
pharynx musculature	SMED30010046	h1SMcG0006787	dd_Smed_v6_2265_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
musculature system	SMED30010046	h1SMcG0006787	dd_Smed_v6_2265_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
pharynx musculature	SMED30010046	h1SMcG0006787	dd_Smed_v6_1693_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
musculature system	SMED30010046	h1SMcG0006787	dd_Smed_v6_1693_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
reproductive organ	SMED30010046	h1SMcG0006787	Contig15693	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30010046	h1SMcG0006787	Contig15693	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
testis primordium	SMED30010046	h1SMcG0006787	Contig5941_SE3	GPL10652	PMID:20844018 Wang et al., 2010	juvenile stage

Note: Hover over icons to view figure legend

Alignments

SMED30010046 aligns in the following genomic locations:


Alignment Location	Alignment Score
v31.009930:5810..6113 +	1502

Homology

[Close]

BLAST of SMED30010046 vs. Ensembl Human
Match: HSP90B1 (heat shock protein 90 beta family member 1 [Source:HGNC Symbol;Acc:HGNC:12028])

HSP 1 Score: 115.161 bits (287), Expect = 8.769e-31
Identity = 56/83 (67.47%), Postives = 68/83 (81.93%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNV----EFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HFTAEGEV FK+IL++P  +      E+ S  K +D IKLYV+RVFITDDF D+MPKYL+F+KG++DSDDLPLNVSRETLQQH
Sbjct:  374 HFTAEGEVTFKSILFVPTSAPRGLFDEYGS--KKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 454

[Close]

BLAST of SMED30010046 vs. Ensembl Human
Match: HSP90AA1 (heat shock protein 90 alpha family class A member 1 [Source:HGNC Symbol;Acc:HGNC:5253])

HSP 1 Score: 97.8265 bits (242), Expect = 1.112e-24
Identity = 38/78 (48.72%), Postives = 65/78 (83.33%), Query Frame = -3

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ ++++P+YL+F++G++DS+DLPLN+SRE LQQ
Sbjct:  450 HFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQ 527

[Close]

BLAST of SMED30010046 vs. Ensembl Human
Match: HSP90AA1 (heat shock protein 90 alpha family class A member 1 [Source:HGNC Symbol;Acc:HGNC:5253])

HSP 1 Score: 97.8265 bits (242), Expect = 1.168e-24
Identity = 38/78 (48.72%), Postives = 65/78 (83.33%), Query Frame = -3

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ ++++P+YL+F++G++DS+DLPLN+SRE LQQ
Sbjct:  328 HFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQ 405

[Close]

BLAST of SMED30010046 vs. Ensembl Human
Match: HSP90AB1 (heat shock protein 90 alpha family class B member 1 [Source:HGNC Symbol;Acc:HGNC:5258])

HSP 1 Score: 90.8929 bits (224), Expect = 3.508e-22
Identity = 40/78 (51.28%), Postives = 64/78 (82.05%), Query Frame = -3

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L+IP+++  +     K  +NIKLYV+RVFI D  D+++P+YL+F++G++DS+DLPLN+SRE LQQ
Sbjct:  320 HFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQ 397

[Close]

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L+IP+++  +     K  +NIKLYV+RVFI D  D+++P+YL+F++G++DS+DLPLN+SRE LQQ
Sbjct:  320 HFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQ 397

[Close]

BLAST of SMED30010046 vs. Ensembl Celegans
Match: enpl-1 (Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q22235])

HSP 1 Score: 121.324 bits (303), Expect = 2.595e-33
Identity = 57/80 (71.25%), Postives = 69/80 (86.25%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKS-NVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HF+AEGEV F++ILY+PKKS N  F +  K  +NIKLYV+RVFITDDF D++PKYLSF++GI+DSDDLPLNVSRE LQQH
Sbjct:  281 HFSAEGEVSFRSILYVPKKSPNDMFQNYGKVIENIKLYVRRVFITDDFADMLPKYLSFIRGIVDSDDLPLNVSRENLQQH 360

[Close]

Query:   60 HFTAEGEVQFKAILYIPKKS-NVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HF+AEGEV F++ILY+PKKS N  F +  K  +NIKLYV+RVFITDDF D++PKYLSF++GI+DSDDLPLNVSRE LQQH
Sbjct:  281 HFSAEGEVSFRSILYVPKKSPNDMFQNYGKVIENIKLYVRRVFITDDFADMLPKYLSFIRGIVDSDDLPLNVSRENLQQH 360

[Close]

Query:   60 HFTAEGEVQFKAILYIPKKS-NVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HF+AEGEV F++ILY+PKKS N  F +  K  +NIKLYV+RVFITDDF D++PKYLSF++GI+DSDDLPLNVSRE LQQH
Sbjct:  281 HFSAEGEVSFRSILYVPKKSPNDMFQNYGKVIENIKLYVRRVFITDDFADMLPKYLSFIRGIVDSDDLPLNVSRENLQQH 360

[Close]

Query:   60 HFTAEGEVQFKAILYIPKKS-NVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HF+AEGEV F++ILY+PKKS N  F +  K  +NIKLYV+RVFITDDF D++PKYLSF++GI+DSDDLPLNVSRE LQQH
Sbjct:  281 HFSAEGEVSFRSILYVPKKSPNDMFQNYGKVIENIKLYVRRVFITDDFADMLPKYLSFIRGIVDSDDLPLNVSRENLQQH 360

[Close]

Query:   60 HFTAEGEVQFKAILYIPKKS-NVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HF+AEGEV F++ILY+PKKS N  F +  K  +NIKLYV+RVFITDDF D++PKYLSF++GI+DSDDLPLNVSRE LQQH
Sbjct:  281 HFSAEGEVSFRSILYVPKKSPNDMFQNYGKVIENIKLYVRRVFITDDFADMLPKYLSFIRGIVDSDDLPLNVSRENLQQH 360

[Close]

BLAST of SMED30010046 vs. Ensembl Fly
Match: Gp93 (gene:FBgn0039562 transcript:FBtr0085254)

HSP 1 Score: 123.25 bits (308), Expect = 7.323e-34
Identity = 56/82 (68.29%), Postives = 69/82 (84.15%), Query Frame = -3

Query:   60 KTHFTAEGEVQFKAILYIPKKSNVE-FNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 302
            +THF AEGEV FK++LY+PK    E FN     +DNIKLYV+RVFITD+F+D+MP YLSF++G++DSDDLPLNVSRETLQQH
Sbjct:  372 QTHFIAEGEVTFKSLLYVPKVQPSESFNRYGTKSDNIKLYVRRVFITDEFNDMMPNYLSFIRGVVDSDDLPLNVSRETLQQH 453

[Close]

BLAST of SMED30010046 vs. Ensembl Fly
Match: Hsp83 (gene:FBgn0001233 transcript:FBtr0332873)

HSP 1 Score: 102.834 bits (255), Expect = 1.122e-26
Identity = 42/79 (53.16%), Postives = 66/79 (83.54%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HF+ EG+++F+A+L+IP+++  +     K  +NIKLYV+RVFI D+ +D++P+YL+FMKG++DS+DLPLN+SRE LQQ+
Sbjct:  313 HFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQN 391

[Close]

BLAST of SMED30010046 vs. Ensembl Fly
Match: Hsp83 (gene:FBgn0001233 transcript:FBtr0073040)

HSP 1 Score: 102.834 bits (255), Expect = 1.122e-26
Identity = 42/79 (53.16%), Postives = 66/79 (83.54%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HF+ EG+++F+A+L+IP+++  +     K  +NIKLYV+RVFI D+ +D++P+YL+FMKG++DS+DLPLN+SRE LQQ+
Sbjct:  313 HFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQN 391

[Close]

BLAST of SMED30010046 vs. Ensembl Fly
Match: Trap1 (gene:FBgn0026761 transcript:FBtr0086149)

HSP 1 Score: 67.0106 bits (162), Expect = 3.993e-14
Identity = 29/77 (37.66%), Postives = 47/77 (61.04%), Query Frame = -3

Query:   66 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQ 296
            H+ A+  +   A+LY P+     F      N  + LY ++V I    + ++PK+L F+KG++DS+D+PLN+SRE LQ
Sbjct:  318 HYNADVPLSIHALLYFPEGKPGLFEMSRDGNTGVALYTRKVLIQSKTEHLLPKWLRFVKGVVDSEDIPLNLSRELLQ 394

[Close]

BLAST of SMED30010046 vs. Ensembl Fly
Match: Trap1 (gene:FBgn0026761 transcript:FBtr0336666)

HSP 1 Score: 67.0106 bits (162), Expect = 3.993e-14
Identity = 29/77 (37.66%), Postives = 47/77 (61.04%), Query Frame = -3

Query:   66 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQ 296
            H+ A+  +   A+LY P+     F      N  + LY ++V I    + ++PK+L F+KG++DS+D+PLN+SRE LQ
Sbjct:  318 HYNADVPLSIHALLYFPEGKPGLFEMSRDGNTGVALYTRKVLIQSKTEHLLPKWLRFVKGVVDSEDIPLNLSRELLQ 394

[Close]

BLAST of SMED30010046 vs. Ensembl Zebrafish
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 114.775 bits (286), Expect = 9.089e-31
Identity = 55/83 (66.27%), Postives = 68/83 (81.93%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNV----EFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HFTAEGEV FK+IL++P  +      E+ +  K ND IKL+V+RVFITDDF D+MPKYL+F+KG++DSDDLPLNVSRETLQQH
Sbjct:  375 HFTAEGEVTFKSILFVPASAPRGLFDEYGT--KKNDFIKLFVRRVFITDDFHDMMPKYLNFIKGVVDSDDLPLNVSRETLQQH 455

[Close]

BLAST of SMED30010046 vs. Ensembl Zebrafish
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 114.39 bits (285), Expect = 1.100e-30
Identity = 55/83 (66.27%), Postives = 68/83 (81.93%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNV----EFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HFTAEGEV FK+IL++P  +      E+ +  K ND IKL+V+RVFITDDF D+MPKYL+F+KG++DSDDLPLNVSRETLQQH
Sbjct:  374 HFTAEGEVTFKSILFVPASAPRGLFDEYGT--KKNDFIKLFVRRVFITDDFHDMMPKYLNFIKGVVDSDDLPLNVSRETLQQH 454

[Close]

BLAST of SMED30010046 vs. Ensembl Zebrafish
Match: hsp90aa1.1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 [Source:NCBI gene;Acc:30591])

HSP 1 Score: 98.9821 bits (245), Expect = 3.095e-25
Identity = 39/78 (50.00%), Postives = 65/78 (83.33%), Query Frame = -3

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ ++++P+YL+F+KG++DS+DLPLN+SRE LQQ
Sbjct:  321 HFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELIPEYLNFIKGVVDSEDLPLNISREMLQQ 398

[Close]

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ ++++P+YL+F+KG++DS+DLPLN+SRE LQQ
Sbjct:  321 HFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELIPEYLNFIKGVVDSEDLPLNISREMLQQ 398

[Close]

BLAST of SMED30010046 vs. Ensembl Zebrafish
Match: hsp90aa1.2 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-031001-3])

HSP 1 Score: 90.8929 bits (224), Expect = 1.912e-22
Identity = 40/78 (51.28%), Postives = 65/78 (83.33%), Query Frame = -3

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ D+++P+YL+F+KG++DS+DLPLN+SRE LQQ
Sbjct:  330 HFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCDELIPEYLNFIKGVVDSEDLPLNISREMLQQ 407

[Close]

BLAST of SMED30010046 vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 113.62 bits (283), Expect = 3.190e-30
Identity = 56/83 (67.47%), Postives = 68/83 (81.93%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNV----EFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HFTAEGEV FK+IL+IP  +      E+ S  K +D IKL+V+RVFITDDF D+MPKYL+F+KG++DSDDLPLNVSRETLQQH
Sbjct:  373 HFTAEGEVTFKSILFIPTTAPRGLFDEYGS--KKSDFIKLFVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 453

[Close]

BLAST of SMED30010046 vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 113.235 bits (282), Expect = 3.984e-30
Identity = 56/83 (67.47%), Postives = 68/83 (81.93%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNV----EFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HFTAEGEV FK+IL+IP  +      E+ S  K +D IKL+V+RVFITDDF D+MPKYL+F+KG++DSDDLPLNVSRETLQQH
Sbjct:  364 HFTAEGEVTFKSILFIPTTAPRGLFDEYGS--KKSDFIKLFVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 444

[Close]

BLAST of SMED30010046 vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 113.235 bits (282), Expect = 4.203e-30
Identity = 56/83 (67.47%), Postives = 68/83 (81.93%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNV----EFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HFTAEGEV FK+IL+IP  +      E+ S  K +D IKL+V+RVFITDDF D+MPKYL+F+KG++DSDDLPLNVSRETLQQH
Sbjct:  375 HFTAEGEVTFKSILFIPTTAPRGLFDEYGS--KKSDFIKLFVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 455

[Close]

BLAST of SMED30010046 vs. Ensembl Xenopus
Match: hsp90aa1.1 (heat shock protein 90kDa alpha family class A member 1 [Source:NCBI gene;Acc:549036])

HSP 1 Score: 97.8265 bits (242), Expect = 8.933e-25
Identity = 38/78 (48.72%), Postives = 65/78 (83.33%), Query Frame = -3

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ ++++P+YL+F++G++DS+DLPLN+SRE LQQ
Sbjct:  325 HFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQ 402

[Close]

BLAST of SMED30010046 vs. Ensembl Xenopus
Match: hsp90aa1.1 (heat shock protein 90kDa alpha family class A member 1 [Source:NCBI gene;Acc:549036])

HSP 1 Score: 97.8265 bits (242), Expect = 9.800e-25
Identity = 38/78 (48.72%), Postives = 65/78 (83.33%), Query Frame = -3

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ ++++P+YL+F++G++DS+DLPLN+SRE LQQ
Sbjct:  333 HFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQ 410

[Close]

BLAST of SMED30010046 vs. Ensembl Mouse
Match: Hsp90b1 (heat shock protein 90, beta (Grp94), member 1 [Source:MGI Symbol;Acc:MGI:98817])

HSP 1 Score: 115.161 bits (287), Expect = 9.092e-32
Identity = 56/83 (67.47%), Postives = 68/83 (81.93%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNV----EFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HFTAEGEV FK+IL++P  +      E+ S  K +D IKLYV+RVFITDDF D+MPKYL+F+KG++DSDDLPLNVSRETLQQH
Sbjct:   50 HFTAEGEVTFKSILFVPTSAPRGLFDEYGS--KKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 130

[Close]

BLAST of SMED30010046 vs. Ensembl Mouse
Match: Hsp90b1 (heat shock protein 90, beta (Grp94), member 1 [Source:MGI Symbol;Acc:MGI:98817])

HSP 1 Score: 115.161 bits (287), Expect = 5.790e-31
Identity = 56/83 (67.47%), Postives = 68/83 (81.93%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNV----EFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HFTAEGEV FK+IL++P  +      E+ S  K +D IKLYV+RVFITDDF D+MPKYL+F+KG++DSDDLPLNVSRETLQQH
Sbjct:  374 HFTAEGEVTFKSILFVPTSAPRGLFDEYGS--KKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 454

[Close]

BLAST of SMED30010046 vs. Ensembl Mouse
Match: Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1 [Source:MGI Symbol;Acc:MGI:96250])

HSP 1 Score: 97.8265 bits (242), Expect = 8.667e-25
Identity = 38/78 (48.72%), Postives = 65/78 (83.33%), Query Frame = -3

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ ++++P+YL+F++G++DS+DLPLN+SRE LQQ
Sbjct:  329 HFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQ 406

[Close]

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ ++++P+YL+F++G++DS+DLPLN+SRE LQQ
Sbjct:  329 HFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQ 406

[Close]

BLAST of SMED30010046 vs. Ensembl Mouse
Match: Hsp90ab1 (heat shock protein 90 alpha (cytosolic), class B member 1 [Source:MGI Symbol;Acc:MGI:96247])

HSP 1 Score: 89.7373 bits (221), Expect = 1.472e-23
Identity = 40/78 (51.28%), Postives = 64/78 (82.05%), Query Frame = -3

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L+IP+++  +     K  +NIKLYV+RVFI D  D+++P+YL+F++G++DS+DLPLN+SRE LQQ
Sbjct:  107 HFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQ 184

[Close]

BLAST of SMED30010046 vs. UniProt/SwissProt
Match: sp|Q22235|ENPL1_CAEEL (Endoplasmin homolog OS=Caenorhabditis elegans OX=6239 GN=enpl-1 PE=3 SV=1)

HSP 1 Score: 121.324 bits (303), Expect = 3.583e-32
Identity = 57/80 (71.25%), Postives = 69/80 (86.25%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKS-NVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HF+AEGEV F++ILY+PKKS N  F +  K  +NIKLYV+RVFITDDF D++PKYLSF++GI+DSDDLPLNVSRE LQQH
Sbjct:  353 HFSAEGEVSFRSILYVPKKSPNDMFQNYGKVIENIKLYVRRVFITDDFADMLPKYLSFIRGIVDSDDLPLNVSRENLQQH 432

[Close]

BLAST of SMED30010046 vs. UniProt/SwissProt
Match: sp|Q95M18|ENPL_BOVIN (Endoplasmin OS=Bos taurus OX=9913 GN=HSP90B1 PE=2 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 3.468e-30
Identity = 56/83 (67.47%), Postives = 68/83 (81.93%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNV----EFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HFTAEGEV FK+IL++P  +      E+ S  K +D IKLYV+RVFITDDF D+MPKYL+F+KG++DSDDLPLNVSRETLQQH
Sbjct:  374 HFTAEGEVTFKSILFVPTSAPRGLFDEYGS--KKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 454

[Close]

BLAST of SMED30010046 vs. UniProt/SwissProt
Match: sp|Q66HD0|ENPL_RAT (Endoplasmin OS=Rattus norvegicus OX=10116 GN=Hsp90b1 PE=1 SV=2)

HSP 1 Score: 115.161 bits (287), Expect = 4.012e-30
Identity = 56/83 (67.47%), Postives = 68/83 (81.93%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNV----EFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HFTAEGEV FK+IL++P  +      E+ S  K +D IKLYV+RVFITDDF D+MPKYL+F+KG++DSDDLPLNVSRETLQQH
Sbjct:  374 HFTAEGEVTFKSILFVPTSAPRGLFDEYGS--KKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 454

[Close]

BLAST of SMED30010046 vs. UniProt/SwissProt
Match: sp|P08113|ENPL_MOUSE (Endoplasmin OS=Mus musculus OX=10090 GN=Hsp90b1 PE=1 SV=2)

HSP 1 Score: 115.161 bits (287), Expect = 4.050e-30
Identity = 56/83 (67.47%), Postives = 68/83 (81.93%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNV----EFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HFTAEGEV FK+IL++P  +      E+ S  K +D IKLYV+RVFITDDF D+MPKYL+F+KG++DSDDLPLNVSRETLQQH
Sbjct:  374 HFTAEGEVTFKSILFVPTSAPRGLFDEYGS--KKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 454

[Close]

BLAST of SMED30010046 vs. UniProt/SwissProt
Match: sp|P14625|ENPL_HUMAN (Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 4.211e-30
Identity = 56/83 (67.47%), Postives = 68/83 (81.93%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNV----EFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HFTAEGEV FK+IL++P  +      E+ S  K +D IKLYV+RVFITDDF D+MPKYL+F+KG++DSDDLPLNVSRETLQQH
Sbjct:  374 HFTAEGEVTFKSILFVPTSAPRGLFDEYGS--KKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 454

[Close]

BLAST of SMED30010046 vs. TrEMBL
Match: A0A2R4NBU5 (Heat shock protein 902 OS=Dugesia japonica OX=6161 GN=hsp902 PE=2 SV=1)

HSP 1 Score: 152.14 bits (383), Expect = 1.259e-40
Identity = 90/101 (89.11%), Postives = 96/101 (95.05%), Query Frame = -3

Query:    3 KTHFTAEGEVQFKAILYIPKKSNVEFNS-VDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQHXXXXXXXXXXXXXXLDMFK 302
            KTHFTAEGEV FKAILY+PKKSN+E N+ V+K NDNIKLYVKRVFITDDFDDIMPKYLSF+KGIIDSDDLPLNVSRETLQQHKLLK+IKKKLVRKTLDM K
Sbjct:  386 KTHFTAEGEVSFKAILYVPKKSNIEINNIVEKKNDNIKLYVKRVFITDDFDDIMPKYLSFIKGIIDSDDLPLNVSRETLQQHKLLKLIKKKLVRKTLDMLK 486

[Close]

BLAST of SMED30010046 vs. TrEMBL
Match: A0A3P6T7C1 (HATPase_c domain-containing protein OS=Litomosoides sigmodontis OX=42156 GN=NLS_LOCUS4392 PE=3 SV=1)

HSP 1 Score: 130.568 bits (327), Expect = 6.378e-33
Identity = 78/99 (78.79%), Postives = 87/99 (87.88%), Query Frame = -3

Query:    3 HFTAEGEVQFKAILYIPKKSNVE-FNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQHXXXXXXXXXXXXXXLDMFK 296
            HFTAEGEV FK+ILY+P+ S  + F +  K  DNIKLYV+RVFITDDF DIMPKYLSF++GI+DSDDLPLNVSRETLQQHKLLKVIKKKLVRK LDMFK
Sbjct:  463 HFTAEGEVTFKSILYVPRHSPFDMFQNYGKGTDNIKLYVRRVFITDDFHDIMPKYLSFIRGIVDSDDLPLNVSRETLQQHKLLKVIKKKLVRKVLDMFK 561

[Close]

BLAST of SMED30010046 vs. TrEMBL
Match: A0A0N4TMR3 (HATPase_c domain-containing protein OS=Brugia pahangi OX=6280 PE=3 SV=1)

HSP 1 Score: 130.183 bits (326), Expect = 6.486e-33
Identity = 77/99 (77.78%), Postives = 87/99 (87.88%), Query Frame = -3

Query:    3 HFTAEGEVQFKAILYIPKKSNVE-FNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQHXXXXXXXXXXXXXXLDMFK 296
            HFTAEGEV FK+ILY+P+ S  + F +  K  DNIKLYV+RVFITDDF DIMPKYLSF++GI+DSDDLPLNVSRETLQQHKLLKVI+KKLVRK LDMFK
Sbjct:  391 HFTAEGEVTFKSILYVPRHSPFDMFQNYGKGTDNIKLYVRRVFITDDFHDIMPKYLSFIRGIVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKVLDMFK 489

[Close]

BLAST of SMED30010046 vs. TrEMBL
Match: A0A4E9ERW8 (HATPase_c domain-containing protein OS=Brugia malayi OX=6279 GN=Bma-enpl-1 PE=3 SV=1)

HSP 1 Score: 130.183 bits (326), Expect = 6.827e-33
Identity = 77/99 (77.78%), Postives = 87/99 (87.88%), Query Frame = -3

Query:    3 HFTAEGEVQFKAILYIPKKSNVE-FNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQHXXXXXXXXXXXXXXLDMFK 296
            HFTAEGEV FK+ILY+P+ S  + F +  K  DNIKLYV+RVFITDDF DIMPKYLSF++GI+DSDDLPLNVSRETLQQHKLLKVI+KKLVRK LDMFK
Sbjct:  379 HFTAEGEVTFKSILYVPRHSPFDMFQNYGKGTDNIKLYVRRVFITDDFHDIMPKYLSFIRGIVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKVLDMFK 477

[Close]

BLAST of SMED30010046 vs. TrEMBL
Match: A0A1P6C609 (BMA-ENPL-1, isoform b OS=Brugia malayi OX=6279 GN=bma-enpl-1 PE=3 SV=1)

HSP 1 Score: 130.183 bits (326), Expect = 6.827e-33
Identity = 77/99 (77.78%), Postives = 87/99 (87.88%), Query Frame = -3

Query:    3 HFTAEGEVQFKAILYIPKKSNVE-FNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQHXXXXXXXXXXXXXXLDMFK 296
            HFTAEGEV FK+ILY+P+ S  + F +  K  DNIKLYV+RVFITDDF DIMPKYLSF++GI+DSDDLPLNVSRETLQQHKLLKVI+KKLVRK LDMFK
Sbjct:  379 HFTAEGEVTFKSILYVPRHSPFDMFQNYGKGTDNIKLYVRRVFITDDFHDIMPKYLSFIRGIVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKVLDMFK 477

[Close]

BLAST of SMED30010046 vs. Ensembl Cavefish
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 115.546 bits (288), Expect = 4.410e-31
Identity = 56/83 (67.47%), Postives = 68/83 (81.93%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNV----EFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HFTAEGEV FK+IL++P  +      E+ S  K ND IKL+V+RVFITDDF D+MPKYL+F+KG++DSDDLPLNVSRETLQQH
Sbjct:  369 HFTAEGEVTFKSILFVPASAPRGLFDEYGS--KKNDFIKLFVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 449

[Close]

BLAST of SMED30010046 vs. Ensembl Cavefish
Match: hsp90aa1.2 (Astyanax mexicanus heat shock protein HSP 90-alpha 1-like (LOC103024454), mRNA. [Source:RefSeq mRNA;Acc:NM_001291257])

HSP 1 Score: 102.449 bits (254), Expect = 1.339e-26
Identity = 41/78 (52.56%), Postives = 65/78 (83.33%), Query Frame = -3

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ +++MP+YL+FMKG++DS+DLPLN+SRE LQQ
Sbjct:  319 HFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELMPEYLNFMKGVVDSEDLPLNISREMLQQ 396

[Close]

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ +++MP+YL+FMKG++DS+DLPLN+SRE LQQ
Sbjct:  319 HFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELMPEYLNFMKGVVDSEDLPLNISREMLQQ 396

[Close]

BLAST of SMED30010046 vs. Ensembl Cavefish
Match: hsp90aa1.2 (Astyanax mexicanus heat shock protein HSP 90-alpha 1-like (LOC103024454), mRNA. [Source:RefSeq mRNA;Acc:NM_001291257])

HSP 1 Score: 90.5077 bits (223), Expect = 2.634e-22
Identity = 39/78 (50.00%), Postives = 65/78 (83.33%), Query Frame = -3

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ D+++P+YL+F++G++DS+DLPLN+SRE LQQ
Sbjct:  327 HFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCDELIPEYLNFIRGVVDSEDLPLNISREMLQQ 404

[Close]

BLAST of SMED30010046 vs. Ensembl Cavefish
Match: hsp90aa1.2 (Astyanax mexicanus heat shock protein HSP 90-alpha 1-like (LOC103024454), mRNA. [Source:RefSeq mRNA;Acc:NM_001291257])

HSP 1 Score: 90.1225 bits (222), Expect = 2.765e-22
Identity = 39/78 (50.00%), Postives = 65/78 (83.33%), Query Frame = -3

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ D+++P+YL+F++G++DS+DLPLN+SRE LQQ
Sbjct:  326 HFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCDELIPEYLNFIRGVVDSEDLPLNISREMLQQ 403

[Close]

BLAST of SMED30010046 vs. Ensembl Sea Lamprey
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 112.849 bits (281), Expect = 6.742e-31
Identity = 53/83 (63.86%), Postives = 67/83 (80.72%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNV----EFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HFTAEGEV F++IL++P  +      E+ +  K  D IK+YV+RVFITDDF D+MPKYL+F+KG++DSDDLPLNVSRETLQQH
Sbjct:  351 HFTAEGEVTFRSILFVPTSAPRGMFDEYGT--KKTDFIKMYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 431

[Close]

BLAST of SMED30010046 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003399.1 (pep scaffold:Pmarinus_7.0:GL479675:6143:15195:1 gene:ENSPMAG00000002912.1 transcript:ENSPMAT00000003399.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 90.8929 bits (224), Expect = 3.245e-23
Identity = 40/78 (51.28%), Postives = 65/78 (83.33%), Query Frame = -3

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ +D++P+YL+F+KG++DS+DLPLN+SRE LQQ
Sbjct:  298 HFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEDLIPEYLNFIKGVVDSEDLPLNISREMLQQ 375

[Close]

BLAST of SMED30010046 vs. Ensembl Yeast
Match: HSP82 (Hsp90 chaperone; redundant in function with Hsc82p; required for pheromone signaling, negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding, nucleotide addition; protein abundance increases in response to DNA replication stress; contains two acid-rich unstructured regions that promote solubility of chaperone-substrate complexes; HSP82 has a paralog, HSC82, that arose from the whole genome duplication [Source:SGD;Acc:S000006161])

HSP 1 Score: 105.916 bits (263), Expect = 1.052e-28
Identity = 44/79 (55.70%), Postives = 67/79 (84.81%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HF+ EG+++F+AIL+IPK++  +     K  +NIKLYV+RVFITD+ +D++P++LSF+KG++DS+DLPLN+SRE LQQ+
Sbjct:  308 HFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQN 386

[Close]

BLAST of SMED30010046 vs. Ensembl Yeast
Match: HSC82 (Cytoplasmic chaperone of the Hsp90 family; plays a role in determining prion variants; redundant in function and nearly identical with Hsp82p, and together they are essential; expressed constitutively at 10-fold higher basal levels than HSP82 and induced 2-3 fold by heat shock; contains two acid-rich unstructured regions that promote the solubility of chaperone-substrate complexes; HSC82 has a paralog, HSP82, that arose from the whole genome duplication [Source:SGD;Acc:S000004798])

HSP 1 Score: 105.916 bits (263), Expect = 1.158e-28
Identity = 44/79 (55.70%), Postives = 67/79 (84.81%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HF+ EG+++F+AIL+IPK++  +     K  +NIKLYV+RVFITD+ +D++P++LSF+KG++DS+DLPLN+SRE LQQ+
Sbjct:  304 HFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQN 382

[Close]

BLAST of SMED30010046 vs. Ensembl Nematostella
Match: EDO45344 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RT97])

HSP 1 Score: 112.464 bits (280), Expect = 1.513e-30
Identity = 53/83 (63.86%), Postives = 69/83 (83.13%), Query Frame = -3

Query:   60 KTHFTAEGEVQFKAILYIPKK--SNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 302
            K HF AEGEV F++IL++PK   SN+ F+   K  D IKL+V+RVFITD+F+++MPKYLSF++G++DSDDLPLNVSRE LQQH
Sbjct:  389 KIHFVAEGEVTFRSILFVPKAAPSNL-FSDYGKKMDAIKLFVRRVFITDNFEEMMPKYLSFIRGVVDSDDLPLNVSREQLQQH 470

[Close]

BLAST of SMED30010046 vs. Ensembl Nematostella
Match: HSP90 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJ66])

HSP 1 Score: 102.064 bits (253), Expect = 7.803e-27
Identity = 41/79 (51.90%), Postives = 65/79 (82.28%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HF+ EG+++F+A+L++PK++  +     K  +NIKLYV+RVFI D+ +D++P+YL F+KG++DS+DLPLN+SRE LQQ+
Sbjct:  322 HFSVEGQLEFRALLFVPKRAPFDLFESRKKRNNIKLYVRRVFIMDNCEDLIPEYLGFIKGVVDSEDLPLNISREMLQQN 400

[Close]

BLAST of SMED30010046 vs. Ensembl Nematostella
Match: EDO45666 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RS03])

HSP 1 Score: 65.0846 bits (157), Expect = 7.738e-14
Identity = 27/77 (35.06%), Postives = 48/77 (62.34%), Query Frame = -3

Query:   66 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQ 296
            H+  +  +  ++I Y P+     FN + +    I LY +RV I    + ++P++L F++G++DS+D+PLN+SRE LQ
Sbjct:  259 HYKTDAPLNIRSIFYFPETLPQMFN-MQQMESGISLYSRRVLIQAKAEKVLPRWLRFIRGVVDSEDIPLNLSRELLQ 334

[Close]

BLAST of SMED30010046 vs. Ensembl Medaka
Match: hsp90b1 (heat shock protein 90 beta family member 1 [Source:NCBI gene;Acc:101166123])

HSP 1 Score: 115.931 bits (289), Expect = 2.973e-31
Identity = 55/83 (66.27%), Postives = 69/83 (83.13%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNV----EFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HFTAEGEV FK+IL++P  +      E+ S  K ND +KL+V+RVFITDDF+D+MPKYL+F+KG++DSDDLPLNVSRETLQQH
Sbjct:  378 HFTAEGEVTFKSILFVPSAAPRGLFDEYGS--KKNDFVKLFVRRVFITDDFNDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 458

[Close]

BLAST of SMED30010046 vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 100.523 bits (249), Expect = 7.439e-26
Identity = 40/78 (51.28%), Postives = 65/78 (83.33%), Query Frame = -3

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ D+++P+YL+F+KG++DS+DLPLN+SRE LQQ
Sbjct:  320 HFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCDELIPEYLNFIKGVVDSEDLPLNISREMLQQ 397

[Close]

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ D+++P+YL+F+KG++DS+DLPLN+SRE LQQ
Sbjct:  320 HFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCDELIPEYLNFIKGVVDSEDLPLNISREMLQQ 397

[Close]

BLAST of SMED30010046 vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 99.7525 bits (247), Expect = 1.346e-25
Identity = 39/78 (50.00%), Postives = 65/78 (83.33%), Query Frame = -3

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ D+++P+YL+F++G++DS+DLPLN+SRE LQQ
Sbjct:  320 HFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCDELIPEYLNFIRGVVDSEDLPLNISREMLQQ 397

[Close]

BLAST of SMED30010046 vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 90.5077 bits (223), Expect = 2.284e-22
Identity = 39/78 (50.00%), Postives = 65/78 (83.33%), Query Frame = -3

Query:   63 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQ 296
            HF+ EG+++F+A+L++P+++  +     K  +NIKLYV+RVFI D+ D+++P+YL+F++G++DS+DLPLN+SRE LQQ
Sbjct:  326 HFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCDELIPEYLNFIRGVVDSEDLPLNISREMLQQ 403

[Close]

BLAST of SMED30010046 vs. Planmine SMEST
Match: SMESG000054819.1 (SMESG000054819.1)

HSP 1 Score: 169.474 bits (428), Expect = 2.445e-50
Identity = 99/100 (99.00%), Postives = 99/100 (99.00%), Query Frame = -3

Query:    3 KTHFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQHXXXXXXXXXXXXXXLDMFK 302
            KTHFTAEGEVQFKAILYIPKKSNVEFNSVDK NDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQHKLLKVIKKKLVRKTLDMFK
Sbjct:  380 KTHFTAEGEVQFKAILYIPKKSNVEFNSVDKKNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQHKLLKVIKKKLVRKTLDMFK 479

[Close]

BLAST of SMED30010046 vs. Planmine SMEST
Match: SMESG000041107.1 (SMESG000041107.1)

HSP 1 Score: 116.701 bits (291), Expect = 1.059e-31
Identity = 73/101 (72.28%), Postives = 87/101 (86.14%), Query Frame = -3

Query:    3 KTHFTAEGEVQFKAILYIPKKSNVEF-NSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQHXXXXXXXXXXXXXXLDMFK 302
            K HFTAEGEV FK+IL++P K    +  + + + DNIK+YV+RVFITDDF+D+MPKYLSF+ GI+DSDDLPLNVSRETLQQ+KLLKVIKKKLVRKTLDM K
Sbjct:  375 KIHFTAEGEVTFKSILFVPAKPPYNYYQNPETHRDNIKMYVRRVFITDDFNDMMPKYLSFIVGIVDSDDLPLNVSRETLQQNKLLKVIKKKLVRKTLDMLK 475

[Close]

BLAST of SMED30010046 vs. Planmine SMEST
Match: SMESG000068132.1 (SMESG000068132.1)

HSP 1 Score: 107.071 bits (266), Expect = 2.655e-28
Identity = 50/81 (61.73%), Postives = 62/81 (76.54%), Query Frame = -3

Query:   60 KTHFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 302
            K HF AEGEV FK++LYIP K+       +  + +I+LYV+RVFITD   DI+P+YLSF+ GI+DSDDLPLNVSRETLQQ 
Sbjct:  392 KIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQE 472

[Close]

BLAST of SMED30010046 vs. Planmine SMEST
Match: SMESG000025598.1 (SMESG000025598.1)

HSP 1 Score: 103.99 bits (258), Expect = 3.498e-27
Identity = 44/79 (55.70%), Postives = 65/79 (82.28%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HF  EG+++FKAIL+ PK+++ +     K  +NIKLYV+RVFI D+ +D++P+YLSF+KG++DS+DLPLN+SRE LQQ+
Sbjct:  306 HFAVEGQLEFKAILFCPKRASFDMFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLSFIKGVVDSEDLPLNISREMLQQN 384

[Close]

BLAST of SMED30010046 vs. Planmine SMEST
Match: SMESG000024822.1 (SMESG000024822.1)

HSP 1 Score: 99.7525 bits (247), Expect = 9.368e-26
Identity = 41/79 (51.90%), Postives = 65/79 (82.28%), Query Frame = -3

Query:   60 HFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQH 296
            HF+ EG+++F+A+L+ PK++  +     K  +NIKLYV+RVFI D+ +D++P+YL+F+KG++DS+DLPLN+SRE LQQ+
Sbjct:  311 HFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQN 389

The following BLAST results are available for this feature:

BLAST of SMED30010046 vs. Ensembl Human
BLAST of SMED30010046 vs. Ensembl Celegans
BLAST of SMED30010046 vs. Ensembl Fly
BLAST of SMED30010046 vs. Ensembl Zebrafish
BLAST of SMED30010046 vs. Ensembl Xenopus
BLAST of SMED30010046 vs. Ensembl Mouse
BLAST of SMED30010046 vs. UniProt/SwissProt
BLAST of SMED30010046 vs. TrEMBL
BLAST of SMED30010046 vs. Ensembl Cavefish
BLAST of SMED30010046 vs. Ensembl Sea Lamprey
BLAST of SMED30010046 vs. Ensembl Yeast
BLAST of SMED30010046 vs. Ensembl Nematostella
BLAST of SMED30010046 vs. Ensembl Medaka
BLAST of SMED30010046 vs. Planmine SMEST

BLAST of SMED30010046 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
HSP90B1	8.769e-31	67.47	heat shock protein 90 beta family member 1 [Source...	[more]
HSP90AA1	1.112e-24	48.72	heat shock protein 90 alpha family class A member ...	[more]
HSP90AA1	1.168e-24	48.72	heat shock protein 90 alpha family class A member ...	[more]
HSP90AB1	3.508e-22	51.28	heat shock protein 90 alpha family class B member ...	[more]
HSP90AB1	3.508e-22	51.28	heat shock protein 90 alpha family class B member ...	[more]

BLAST of SMED30010046 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
enpl-1	2.595e-33	71.25	Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;...	[more]
enpl-1	2.595e-33	71.25	Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;...	[more]
enpl-1	2.595e-33	71.25	Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;...	[more]
enpl-1	2.595e-33	71.25	Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;...	[more]
enpl-1	2.595e-33	71.25	Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;...	[more]

BLAST of SMED30010046 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Gp93	7.323e-34	68.29	gene:FBgn0039562 transcript:FBtr0085254	[more]
Hsp83	1.122e-26	53.16	gene:FBgn0001233 transcript:FBtr0332873	[more]
Hsp83	1.122e-26	53.16	gene:FBgn0001233 transcript:FBtr0073040	[more]
Trap1	3.993e-14	37.66	gene:FBgn0026761 transcript:FBtr0086149	[more]
Trap1	3.993e-14	37.66	gene:FBgn0026761 transcript:FBtr0336666	[more]

BLAST of SMED30010046 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hsp90b1	9.089e-31	66.27	heat shock protein 90, beta (grp94), member 1 [Sou...	[more]
hsp90b1	1.100e-30	66.27	heat shock protein 90, beta (grp94), member 1 [Sou...	[more]
hsp90aa1.1	3.095e-25	50.00	heat shock protein 90, alpha (cytosolic), class A ...	[more]
hsp90aa1.1	3.095e-25	50.00	heat shock protein 90, alpha (cytosolic), class A ...	[more]
hsp90aa1.2	1.912e-22	51.28	heat shock protein 90, alpha (cytosolic), class A ...	[more]

BLAST of SMED30010046 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hsp90b1	3.190e-30	67.47	heat shock protein 90kDa beta (Grp94), member 1 [S...	[more]
hsp90b1	3.984e-30	67.47	heat shock protein 90kDa beta (Grp94), member 1 [S...	[more]
hsp90b1	4.203e-30	67.47	heat shock protein 90kDa beta (Grp94), member 1 [S...	[more]
hsp90aa1.1	8.933e-25	48.72	heat shock protein 90kDa alpha family class A memb...	[more]
hsp90aa1.1	9.800e-25	48.72	heat shock protein 90kDa alpha family class A memb...	[more]

BLAST of SMED30010046 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Hsp90b1	9.092e-32	67.47	heat shock protein 90, beta (Grp94), member 1 [Sou...	[more]
Hsp90b1	5.790e-31	67.47	heat shock protein 90, beta (Grp94), member 1 [Sou...	[more]
Hsp90aa1	8.667e-25	48.72	heat shock protein 90, alpha (cytosolic), class A ...	[more]
Hsp90aa1	8.667e-25	48.72	heat shock protein 90, alpha (cytosolic), class A ...	[more]
Hsp90ab1	1.472e-23	51.28	heat shock protein 90 alpha (cytosolic), class B m...	[more]

BLAST of SMED30010046 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q22235\|ENPL1_CAEEL	3.583e-32	71.25	Endoplasmin homolog OS=Caenorhabditis elegans OX=6...	[more]
sp\|Q95M18\|ENPL_BOVIN	3.468e-30	67.47	Endoplasmin OS=Bos taurus OX=9913 GN=HSP90B1 PE=2 ...	[more]
sp\|Q66HD0\|ENPL_RAT	4.012e-30	67.47	Endoplasmin OS=Rattus norvegicus OX=10116 GN=Hsp90...	[more]
sp\|P08113\|ENPL_MOUSE	4.050e-30	67.47	Endoplasmin OS=Mus musculus OX=10090 GN=Hsp90b1 PE...	[more]
sp\|P14625\|ENPL_HUMAN	4.211e-30	67.47	Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=...	[more]

BLAST of SMED30010046 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A2R4NBU5	1.259e-40	89.11	Heat shock protein 902 OS=Dugesia japonica OX=6161...	[more]
A0A3P6T7C1	6.378e-33	78.79	HATPase_c domain-containing protein OS=Litomosoide...	[more]
A0A0N4TMR3	6.486e-33	77.78	HATPase_c domain-containing protein OS=Brugia paha...	[more]
A0A4E9ERW8	6.827e-33	77.78	HATPase_c domain-containing protein OS=Brugia mala...	[more]
A0A1P6C609	6.827e-33	77.78	BMA-ENPL-1, isoform b OS=Brugia malayi OX=6279 GN=...	[more]

BLAST of SMED30010046 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hsp90b1	4.410e-31	67.47	heat shock protein 90, beta (grp94), member 1 [Sou...	[more]
hsp90aa1.2	1.339e-26	52.56	Astyanax mexicanus heat shock protein HSP 90-alpha...	[more]
hsp90aa1.2	1.339e-26	52.56	Astyanax mexicanus heat shock protein HSP 90-alpha...	[more]
hsp90aa1.2	2.634e-22	50.00	Astyanax mexicanus heat shock protein HSP 90-alpha...	[more]
hsp90aa1.2	2.765e-22	50.00	Astyanax mexicanus heat shock protein HSP 90-alpha...	[more]

BLAST of SMED30010046 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
hsp90b1	6.742e-31	63.86	heat shock protein 90, beta (grp94), member 1 [Sou...	[more]
ENSPMAT00000003399.1	3.245e-23	51.28	pep scaffold:Pmarinus_7.0:GL479675:6143:15195:1 ge...	[more]

BLAST of SMED30010046 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
HSP82	1.052e-28	55.70	Hsp90 chaperone; redundant in function with Hsc82p...	[more]
HSC82	1.158e-28	55.70	Cytoplasmic chaperone of the Hsp90 family; plays a...	[more]

BLAST of SMED30010046 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3


Match Name	E-value	Identity	Description
EDO45344	1.513e-30	63.86	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
HSP90	7.803e-27	51.90	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45666	7.738e-14	35.06	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of SMED30010046 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hsp90b1	2.973e-31	66.27	heat shock protein 90 beta family member 1 [Source...	[more]
hsp90aa1.2	7.439e-26	51.28	heat shock protein HSP 90-alpha [Source:NCBI gene;...	[more]
hsp90aa1.2	7.439e-26	51.28	heat shock protein HSP 90-alpha [Source:NCBI gene;...	[more]
hsp90aa1.2	1.346e-25	50.00	heat shock protein HSP 90-alpha [Source:NCBI gene;...	[more]
hsp90aa1.2	2.284e-22	50.00	heat shock protein HSP 90-alpha [Source:NCBI gene;...	[more]

BLAST of SMED30010046 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000054819.1	2.445e-50	99.00	SMESG000054819.1	[more]
SMESG000041107.1	1.059e-31	72.28	SMESG000041107.1	[more]
SMESG000068132.1	2.655e-28	61.73	SMESG000068132.1	[more]
SMESG000025598.1	3.498e-27	55.70	SMESG000025598.1	[more]
SMESG000024822.1	9.368e-26	51.90	SMESG000024822.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30010046 ID=SMED30010046|Name=SMED30010046|organism=Schmidtea mediterranea sexual|type=transcript|length=304bp
TTTTTAAACATGTCTAAAGTTTTACGAACCAGTTTTTTCTTGATTACTTT
GAGAAGTTTGTGTTGCTGTAAAGTTTCCCTTGACACATTCAACGGCAAAT
CATCACTGTCAATGATTCCTTTCATAAATGACAGATATTTTGGCATTATG
TCATCGAAATCATCAGTGATGAAAACTCTTTTCACATAAAGTTTAATATT
GTCATTATTTTTGTCGACAGAATTAAACTCAACATTGGACTTTTTCGGAA
TGTAGAGAATTGCTTTAAATTGCACTTCTCCTTCTGCGGTGAAATGCGTT
TTTG

protein sequence of SMED30010046-orf-1

>SMED30010046-orf-1 ID=SMED30010046-orf-1|Name=SMED30010046-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=100bp
KTHFTAEGEVQFKAILYIPKKSNVEFNSVDKNNDNIKLYVKRVFITDDFD
DIMPKYLSFMKGIIDSDDLPLNVSRETLQQHKLLKVIKKKLVRKTLDMFK

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **INTERPRO**
Term	Definition
IPR001404	Hsp90_fam
IPR020568	Ribosomal_S5_D2-typ_fold

Vocabulary: **molecular function**
Term	Definition
GO:0005524	ATP binding
GO:0051082	unfolded protein binding

Vocabulary: **biological process**
Term	Definition
GO:0006457	protein folding
GO:0006950	response to stress

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..23 score: 0.568

Main menu

SMED30010046

Zeng et. al., 2018

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 31

Owlery

blazegraph-runner