Rho GTPase-activating protein 7

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFE-RIISLSKLLR----DCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVV-SNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVD-DNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H  RW S   +++P  +   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         SVFG  L+    R GQPLP  I  A++Y+R    +  G+FR++G K+RI  L++  E   D  ++     YDVADM+K YFR LPE LMTNKLS T + I  Y+P+    +AI+  I+ LPDENR VLQ+LLYFLSD+T   K  QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE         E E + ++L  L      D  D+  +++  V+ L  E   KFK W S            SE     EL YK       K SEG   +  WR   E+ A    IL ++   +  WD+++   ++  EI DS    Y  V  S  P   R   ++R  + N+      L+  SVD D +PV   +                  +NVL    +IE      KS++ ++ RVDLRG   EWY + + H+    ++ ++
Sbjct:  487 HRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSY---------STSEQA---ELSYK-------KVSEG-PPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVI-EILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVR------------------VNVLLSRYLIEPC-GPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIR 1001          

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFE-RIISLSKLLR----DCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVV-SNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVD-DNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H  RW S   +++P  +   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         SVFG  L+    R GQPLP  I  A++Y+R    +  G+FR++G K+RI  L++  E   D  ++     YDVADM+K YFR LPE LMTNKLS T + I  Y+P+    +AI+  I+ LPDENR VLQ+LLYFLSD+T   K  QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE         E E + ++L  L      D  D+  +++  V+ L  E   KFK W S            SE     EL YK       K SEG   +  WR   E+ A    IL ++   +  WD+++   ++  EI DS    Y  V  S  P   R   ++R  + N+      L+  SVD D +PV   +                  +NVL    +IE      KS++ ++ RVDLRG   EWY + + H+    ++ ++
Sbjct:  551 HRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSY---------STSEQA---ELSYK-------KVSEG-PPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVI-EILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVR------------------VNVLLSRYLIEPC-GPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIR 1065          

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFE-RIISLSKLLR----DCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVV-SNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVD-DNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H  RW S   +++P  +   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         SVFG  L+    R GQPLP  I  A++Y+R    +  G+FR++G K+RI  L++  E   D  ++     YDVADM+K YFR LPE LMTNKLS T + I  Y+P+    +AI+  I+ LPDENR VLQ+LLYFLSD+T   K  QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE         E E + ++L  L      D  D+  +++  V+ L  E   KFK W S            SE     EL YK       K SEG   +  WR   E+ A    IL ++   +  WD+++   ++  EI DS    Y  V  S  P   R   ++R  + N+      L+  SVD D +PV   +                  +NVL    +IE      KS++ ++ RVDLRG   EWY + + H+    ++ ++
Sbjct:  551 HRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSY---------STSEQA---ELSYK-------KVSEG-PPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVI-EILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVR------------------VNVLLSRYLIEPC-GPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIR 1065          

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFE-RIISLSKLLR----DCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVV-SNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVD-DNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H  RW S   +++P  +   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         SVFG  L+    R GQPLP  I  A++Y+R    +  G+FR++G K+RI  L++  E   D  ++     YDVADM+K YFR LPE LMTNKLS T + I  Y+P+    +AI+  I+ LPDENR VLQ+LLYFLSD+T   K  QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE         E E + ++L  L      D  D+  +++  V+ L  E   KFK W S            SE     EL YK       K SEG   +  WR   E+ A    IL ++   +  WD+++   ++  EI DS    Y  V  S  P   R   ++R  + N+      L+  SVD D +PV   +                  +NVL    +IE      KS++ ++ RVDLRG   EWY + + H+    ++ ++
Sbjct:  561 HRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSY---------STSEQA---ELSYK-------KVSEG-PPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVI-EILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVR------------------VNVLLSRYLIEPC-GPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIR 1075          

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFE-RIISLSKLLR----DCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVV-SNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVD-DNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H  RW S   +++P  +   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         SVFG  L+    R GQPLP  I  A++Y+R    +  G+FR++G K+RI  L++  E   D  ++     YDVADM+K YFR LPE LMTNKLS T + I  Y+P+    +AI+  I+ LPDENR VLQ+LLYFLSD+T   K  QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE         E E + ++L  L      D  D+  +++  V+ L  E   KFK W S            SE     EL YK       K SEG   +  WR   E+ A    IL ++   +  WD+++   ++  EI DS    Y  V  S  P   R   ++R  + N+      L+  SVD D +PV   +                  +NVL    +IE      KS++ ++ RVDLRG   EWY + + H+    ++ ++
Sbjct:  595 HRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSY---------STSEQA---ELSYK-------KVSEG-PPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVI-EILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVR------------------VNVLLSRYLIEPC-GPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIR 1109          

Query: 2924 LSHLSLNQFLILKKLAMLRLTSLLESHI---------PSQK---SQFNWKFPKLLS--------QKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTD-------FSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSS---SVSPIRMRKSIHG----PDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFERIISLSKLLRDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVR----IKREISDSVDICYMEVVSNPPQT-------QRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            +  L+L +   L+K A LRL+S+LE +I         P Q+   S+  W   +L+         ++ K  D   +VFG  L     R G  LP  I   +K++R + PE+ GIFR+ G K+RI EL+  IE     TD           Q +DVAD++K YFR LPE LMT K+S    +I + +P+     A+Q+ I+ LPDENR  L++LL FL +++++S+   MT+ NL+VC +PSLF     + +S    V+P   R    G    P  +++++ +A   CL  +I++  ++F + +   +    + +   +  L           S++  +V  LI +++ ++KNWT                  G E+        S K     + + T+R+   + A    ++ ++   R  WD  +   R    +    +D       E + +P +           +T IRG     + ++     Q +   S                          +     +IE     Q SR+N+++RVDL+G S +WY + +  ++ R L  L+
Sbjct:  804 IDSLNLIEMTRLRKTAFLRLSSILERNIEGKGVGLVDPDQEELPSKHVWSVQRLIKRMKINDGQKREKDVDGDGAVFGVGLDVIFNRTGYFLPRPILEVMKFLRNIAPETVGIFRKNGVKSRIAELRSIIESYSGNTDVFVGENLLDSTQVHDVADLLKQYFRDLPEPLMTVKMSEVFANICSVVPDVERITALQYAILLLPDENREALKTLLLFLKEVSRNSQVNNMTAQNLSVCFTPSLFQ----LGASRLDKVTPGNRRHKTVGATGLPSEKEMKEARACQLCLTMLIEYVQTVFMVPDGLDDSMDAEDDNPNLTELG-----LKGPRSFLVDRVIDLIRDHSDQWKNWTIEGS------------FRGIEI--------SSKRPSDSHPLKTFRVWLNVPAGPKSVMMRLLKERYTWDSSVINWRHLEYVSAPDTDIHQYVVNETIGHPTKDCHVARFHSSGLTEIRGACAIAERSVKCTEDQLLGGVS------------------------ATIFDQRFLIEPVSGGQ-SRVNYIARVDLKGRSLQWYNKSFGSIMCRHLDRLR 1319          

Query: 2924 LSHLSLNQFLILKKLAMLRLTSLLESHI---------PSQK---SQFNWKFPKLLS--------QKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTD-------FSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSS---SVSPIRMRKSIHG----PDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFERIISLSKLLRDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVR----IKREISDSVDICYMEVVSNPPQT-------QRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            +  L+L +   L+K A LRL+S+LE +I         P Q+   S+  W   +L+         ++ K  D   +VFG  L     R G  LP  I   +K++R + PE+ GIFR+ G K+RI EL+  IE     TD           Q +DVAD++K YFR LPE LMT K+S    +I + +P+     A+Q+ I+ LPDENR  L++LL FL +++++S+   MT+ NL+VC +PSLF     + +S    V+P   R    G    P  +++++ +A   CL  +I++  ++F + +   +    + +   +  L           S++  +V  LI +++ ++KNWT                  G E+        S K     + + T+R+   + A    ++ ++   R  WD  +   R    +    +D       E + +P +           +T IRG     + ++     Q +   S                          +     +IE     Q SR+N+++RVDL+G S +WY + +  ++ R L  L+
Sbjct:  980 IDSLNLIEMTRLRKTAFLRLSSILERNIEGKGVGLVDPDQEELPSKHVWSVQRLIKRMKINDGQKREKDVDGDGAVFGVGLDVIFNRTGYFLPRPILEVMKFLRNIAPETVGIFRKNGVKSRIAELRSIIESYSGNTDVFVGENLLDSTQVHDVADLLKQYFRDLPEPLMTVKMSEVFANICSVVPDVERITALQYAILLLPDENREALKTLLLFLKEVSRNSQVNNMTAQNLSVCFTPSLFQ----LGASRLDKVTPGNRRHKTVGATGLPSEKEMKEARACQLCLTMLIEYVQTVFMVPDGLDDSMDAEDDNPNLTELG-----LKGPRSFLVDRVIDLIRDHSDQWKNWTIEGS------------FRGIEI--------SSKRPSDSHPLKTFRVWLNVPAGPKSVMMRLLKERYTWDSSVINWRHLEYVSAPDTDIHQYVVNETIGHPTKDCHVARFHSSGLTEIRGACAIAERSVKCTEDQLLGGVS------------------------ATIFDQRFLIEPVSGGQ-SRVNYIARVDLKGRSLQWYNKSFGSIMCRHLDRLR 1495          

Query: 2924 LSHLSLNQFLILKKLAMLRLTSLLESHI---------PSQK---SQFNWKFPKLLS--------QKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTD-------FSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSS---SVSPIRMRKSIHG----PDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFERIISLSKLLRDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVR----IKREISDSVDICYMEVVSNPPQT-------QRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            +  L+L +   L+K A LRL+S+LE +I         P Q+   S+  W   +L+         ++ K  D   +VFG  L     R G  LP  I   +K++R + PE+ GIFR+ G K+RI EL+  IE     TD           Q +DVAD++K YFR LPE LMT K+S    +I + +P+     A+Q+ I+ LPDENR  L++LL FL +++++S+   MT+ NL+VC +PSLF     + +S    V+P   R    G    P  +++++ +A   CL  +I++  ++F + +   +    + +   +  L           S++  +V  LI +++ ++KNWT                  G E+        S K     + + T+R+   + A    ++ ++   R  WD  +   R    +    +D       E + +P +           +T IRG     + ++     Q +   S                          +     +IE     Q SR+N+++RVDL+G S +WY + +  ++ R L  L+
Sbjct:  811 IDSLNLIEMTRLRKTAFLRLSSILERNIEGKGVGLVDPDQEELPSKHVWSVQRLIKRMKINDGQKREKDVDGDGAVFGVGLDVIFNRTGYFLPRPILEVMKFLRNIAPETVGIFRKNGVKSRIAELRSIIESYSGNTDVFVGENLLDSTQVHDVADLLKQYFRDLPEPLMTVKMSEVFANICSVVPDVERITALQYAILLLPDENREALKTLLLFLKEVSRNSQVNNMTAQNLSVCFTPSLFQ----LGASRLDKVTPGNRRHKTVGATGLPSEKEMKEARACQLCLTMLIEYVQTVFMVPDGLDDSMDAEDDNPNLTELG-----LKGPRSFLVDRVIDLIRDHSDQWKNWTIEGS------------FRGIEI--------SSKRPSDSHPLKTFRVWLNVPAGPKSVMMRLLKERYTWDSSVINWRHLEYVSAPDTDIHQYVVNETIGHPTKDCHVARFHSSGLTEIRGACAIAERSVKCTEDQLLGGVS------------------------ATIFDQRFLIEPVSGGQ-SRVNYIARVDLKGRSLQWYNKSFGSIMCRHLDRLR 1326          

Query: 2924 LSHLSLNQFLILKKLAMLRLTSLLESHI---------PSQK---SQFNWKFPKLLS--------QKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTD-------FSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSS---SVSPIRMRKSIHG----PDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFERIISLSKLLRDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVR----IKREISDSVDICYMEVVSNPPQT-------QRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            +  L+L +   L+K A LRL+S+LE +I         P Q+   S+  W   +L+         ++ K  D   +VFG  L     R G  LP  I   +K++R + PE+ GIFR+ G K+RI EL+  IE     TD           Q +DVAD++K YFR LPE LMT K+S    +I + +P+     A+Q+ I+ LPDENR  L++LL FL +++++S+   MT+ NL+VC +PSLF     + +S    V+P   R    G    P  +++++ +A   CL  +I++  ++F + +   +    + +   +  L           S++  +V  LI +++ ++KNWT                  G E+        S K     + + T+R+   + A    ++ ++   R  WD  +   R    +    +D       E + +P +           +T IRG     + ++     Q +   S                          +     +IE     Q SR+N+++RVDL+G S +WY + +  ++ R L  L+
Sbjct:  811 IDSLNLIEMTRLRKTAFLRLSSILERNIEGKGVGLVDPDQEELPSKHVWSVQRLIKRMKINDGQKREKDVDGDGAVFGVGLDVIFNRTGYFLPRPILEVMKFLRNIAPETVGIFRKNGVKSRIAELRSIIESYSGNTDVFVGENLLDSTQVHDVADLLKQYFRDLPEPLMTVKMSEVFANICSVVPDVERITALQYAILLLPDENREALKTLLLFLKEVSRNSQVNNMTAQNLSVCFTPSLFQ----LGASRLDKVTPGNRRHKTVGATGLPSEKEMKEARACQLCLTMLIEYVQTVFMVPDGLDDSMDAEDDNPNLTELG-----LKGPRSFLVDRVIDLIRDHSDQWKNWTIEGS------------FRGIEI--------SSKRPSDSHPLKTFRVWLNVPAGPKSVMMRLLKERYTWDSSVINWRHLEYVSAPDTDIHQYVVNETIGHPTKDCHVARFHSSGLTEIRGACAIAERSVKCTEDQLLGGVS------------------------ATIFDQRFLIEPVSGGQ-SRVNYIARVDLKGRSLQWYNKSFGSIMCRHLDRLR 1326          

Query: 3083 TSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYD---------VADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSL 3565
            T  FG  L +     G  +PP++   ++Y+       +G+FR++     I  L+  I K + + DF     Y           + ++K++FRSL E L TN+L   L ++ + + +     A++  +  LP EN ++L++++ FL+ + ++SK   MT+ NL+V   P+L
Sbjct:   45 TQQFGVPLEFILSHCGGNIPPIVDQLIEYLEAHALTMEGVFRKSANIGSIKRLQDRINKGEKI-DFENDPEYKDNEYVASLHASVLLKTFFRSLGEPLTTNRLYPKLAAL-SEVSKTEKSAAVKEFVKLLPRENYILLKTVIKFLTRVAENSKVNLMTANNLSVVFGPNL 212          

Query: 2918 LELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTD-TSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKT----QDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSV--SPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQ-MEFERIISLSKLLRDC--NDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVIN--VLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLKVA 4504
            +  + +S  Q  I++KLA++ LT  +E + PS +S +NW+ PK + +K K  D     VFG  L     R GQ LP  +  A ++++    +  GIFR++GGK+RI +L++ IE T    + M  F   Q YDVADM+K YFR LPE L+T K+S T ++I  ++P +   +A+Q  ++ LPDENR +L  LL FL+ +  +S+  QMTS NL VCL+ S+FHS     S+SV  SP R  K    PD ++L + KA+H CL FMI+H   ++  ++E ++K     ME  + + L  L      ++W  ++     A I E   K + W S     +   ND S      ++ YK       K  +G + +  WR + EI+ P   +L+ +   R  WD  +   +  +++ D  +I Y   +    Q      ++R  Q ++     V+V  S+D        KPL             +  +   VL    +IE    S +SR+  L+RVD++G + EWY + + H+    L  +++A
Sbjct:  505 MPFAAMSAGQLQIIRKLALVTLTGHMERYCPSHRSGWNWELPKFI-KKIKMPDYKDKKVFGVPLLMILQRSGQTLPLAVRAAFRWLQLNALDQVGIFRKSGGKSRIMKLREQIEVTDSTAECMDVFDLQQAYDVADMLKQYFRELPESLLTTKMSETFVAIFQHLPAEVRLDAVQCAVLLLPDENREILYVLLEFLTIVAANSQQNQMTSNNLGVCLAQSIFHSSISTGSASVSASPRRKGKGSGMPDMKELAEAKASHECLSFMIEHYKQIYTAAKEKLSKCNFSYMEESKPLPLEALGEGMQFHNWRGYLYECTSATIKEGREKTRGWFS-----INSLNDSS-----VDIAYK-------KVGDG-HPLRLWRCSTEIEGPPKEVLEFVIKQRASWDTNLLQCQTVKKLDDRTEI-YQYALDG--QLTTDFCVLRSWQTDLPRGACVIVETSIDH----AKAKPL-------------FGAVRGVVLASRYLIEPC-GSGRSRVMHLARVDVKGKTPEWYNKNYGHICSHYLSRIRLA 1005          

Query: 2918 LELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTD-TSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTD----FSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSV--SPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQ-MEFERIISLSKLLRDC--NDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVIN--VLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLKVA 4504
            +  + +S  Q  I++KLA++ LT  +E + PS +S +NW+ PK + +K K  D     VFG  L     R GQ LP  +  A ++++    +  GIFR++GGK+RI +L++ IE T    +    F   Q YDVADM+K YFR LPE L+T K+S T ++I  ++P +   +A+Q  ++ LPDENR +L  LL FL+ +  +S+  QMTS NL VCL+ S+FHS     S+SV  SP R  K    PD ++L + KA+H CL FMI+H   ++  ++E ++K     ME  + + L  L      ++W  ++     A I E   K + W S     +   ND S      ++ YK       K  +G + +  WR + EI+ P   +L+ +   R  WD  +   +  +++ D  +I Y   +    Q      ++R  Q ++     V+V  S+D        KPL             +  +   VL    +IE    S +SR+  L+RVD++G + EWY + + H+    L  +++A
Sbjct: 1839 MPFAAMSAGQLQIIRKLALVTLTGHMERYCPSHRSGWNWELPKFI-KKIKMPDYKDKKVFGVPLLMILQRSGQTLPLAVRAAFRWLQLNALDQVGIFRKSGGKSRIMKLREQIEVTDSTAECMDVFDLQQAYDVADMLKQYFRELPESLLTTKMSETFVAIFQHLPAEVRLDAVQCAVLLLPDENREILYVLLEFLTIVAANSQQNQMTSNNLGVCLAQSIFHSSISTGSASVSASPRRKGKGSGMPDMKELAEAKASHECLSFMIEHYKQIYTAAKEKLSKCNFSYMEESKPLPLEALGEGMQFHNWRGYLYECTSATIKEGREKTRGWFS-----INSLNDSS-----VDIAYK-------KVGDG-HPLRLWRCSTEIEGPPKEVLEFVIKQRASWDTNLLQCQTVKKLDDRTEI-YQYALDG--QLTTDFCVLRSWQTDLPRGACVIVETSIDH----AKAKPL-------------FGAVRGVVLASRYLIEPC-GSGRSRVMHLARVDVKGKTPEWYNKNYGHICSHYLSRIRLA 2339          

Query: 2918 LELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTD-TSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTD----FSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSV--SPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQ-MEFERIISLSKLLRDC--NDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVIN--VLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLKVA 4504
            +  + +S  Q  I++KLA++ LT  +E + PS +S +NW+ PK + +K K  D     VFG  L     R GQ LP  +  A ++++    +  GIFR++GGK+RI +L++ IE T    +    F   Q YDVADM+K YFR LPE L+T K+S T ++I  ++P +   +A+Q  ++ LPDENR +L  LL FL+ +  +S+  QMTS NL VCL+ S+FHS     S+SV  SP R  K    PD ++L + KA+H CL FMI+H   ++  ++E ++K     ME  + + L  L      ++W  ++     A I E   K + W S     +   ND S      ++ YK       K  +G + +  WR + EI+ P   +L+ +   R  WD  +   +  +++ D  +I Y   +    Q      ++R  Q ++     V+V  S+D        KPL             +  +   VL    +IE    S +SR+  L+RVD++G + EWY + + H+    L  +++A
Sbjct: 1839 MPFAAMSAGQLQIIRKLALVTLTGHMERYCPSHRSGWNWELPKFI-KKIKMPDYKDKKVFGVPLLMILQRSGQTLPLAVRAAFRWLQLNALDQVGIFRKSGGKSRIMKLREQIEVTDSTAECMDVFDLQQAYDVADMLKQYFRELPESLLTTKMSETFVAIFQHLPAEVRLDAVQCAVLLLPDENREILYVLLEFLTIVAANSQQNQMTSNNLGVCLAQSIFHSSISTGSASVSASPRRKGKGSGMPDMKELAEAKASHECLSFMIEHYKQIYTAAKEKLSKCNFSYMEESKPLPLEALGEGMQFHNWRGYLYECTSATIKEGREKTRGWFS-----INSLNDSS-----VDIAYK-------KVGDG-HPLRLWRCSTEIEGPPKEVLEFVIKQRASWDTNLLQCQTVKKLDDRTEI-YQYALDG--QLTTDFCVLRSWQTDLPRGACVIVETSIDH----AKAKPL-------------FGAVRGVVLASRYLIEPC-GSGRSRVMHLARVDVKGKTPEWYNKNYGHICSHYLSRIRLA 2339          

Query: 3137 LPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSK------------TTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRKSIHGPDPRDLEDQKATH--HCLKFMIDHAPSLFRLSEETIN 3739
            +P  + + + Y+   G +  G+FR +  K R+ +L++  +K           P+DVA ++K + R LPE L+ N L  T +  +     +   EAI  +I  LP  +R  L  LL FL+ +  HS               +M SYNLA   +P++  S H+  S                 RD E +      + ++ MI+H   +F +S E +N
Sbjct:  874 VPIFVNNCIDYLEDNGLQQVGLFRVSTSKKRVKQLREEFDKDIYFGISVDTCPHDVATLLKEFLRDLPEPLLCNTLYLTFLKTQRIRNRRLQLEAISHLIRLLPIPHRDTLYVLLVFLAKVAAHSDDIWSTEGCCLTLGNKMDSYNLATVFAPNILRSTHLTFS-----------------RDKEQENMIDAINVVRTMINHYEEIFNISAELLN 1071          

Query: 3137 LPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSK------------TTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETIN 3739
            +P  + + + Y+   G +  G+FR +  K R+ +L++  +K           P+DVA ++K + R LPE L+ N L  T +  +     +   EAI  +I  LP  +R  L  LL FL+ +  HS               +M SYNLA   +P++  S H+  S       M  +I               + ++ MI+H   +F +S E +N
Sbjct:  874 VPIFVNNCIDYLEDNGLQQVGLFRVSTSKKRVKQLREEFDKDIYFGISVDTCPHDVATLLKEFLRDLPEPLLCNTLYLTFLKTQRIRNRRLQLEAISHLIRLLPIPHRDTLYVLLVFLAKVAAHSDDIWSTEGCCLTLGNKMDSYNLATVFAPNILRSTHLTFSRDKEQENMIDAI---------------NVVRTMINHYEEIFNISAELLN 1071          

Query: 2864 FRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDM---TDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRKSIHG-PDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFE----RIISLSKLLRDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNV-INVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
             RW S   +++P  S   L++   S+ Q  +L+K ++L+LT+LLE + P+ K  F+W  PK + +         SVFG  L     R GQPLP  I  A++Y+R+   +  G+FR++G K+RI  L++  E    +    ++     YDVADM+K YFR LPE L+T+KLS T + I  Y+P++   +A++  ++ LPDENR  LQ+LL FLSD+T      QMT  NLAVCL+PSLFH   +   SS   +  RK+  G PD RDL +  A  H L  MI     LF++ EE        ME      R+  L++    CN + S ++  +++L+ E   KFK +            D        EL YKK    S        S+  W++  ++ A A  +L +I   ++ WD ++   RI   +  + ++      S PP   R   ++R    ++   +  LVS SV                  DH++     V  NVL     IE   A+ KSR+  +SR+D RG   EWY + + H+    ++ ++
Sbjct:  607 LRWPSFQSSHRPSLSSTVLQVGCQSVLQMNLLQKYSLLKLTALLERYTPTNKHGFSWAVPKFMKRIKVRDYKDRSVFGVPLQVIVQRSGQPLPQSIQQAMRYLRSQCLDQVGLFRKSGVKSRIQALRQMNESCGAVGGGVNYEGQLAYDVADMLKQYFRDLPEPLLTSKLSDTFLQIYQYVPKEQRLQAVRAAVLLLPDENREALQTLLCFLSDVTASVGENQMTCTNLAVCLAPSLFHLNTLRRESSSPRVMNRKNTLGKPDQRDLNENLAATHGLAHMIQECRKLFQIPEEMSRCRNSYMEQGLSPMRMEVLAENCGSCN-YQSLLKDSIDSLLKEAKDKFKGY------------DSCSTPENAELAYKKVQDGS--------SLRQWKVCVDVPASAEDVLQRILREQERWDEDLLESRIVETLDHNTEVYQYVRNSMPPHPPRDHVVLRSWMTDLPKGVCTLVSVSV------------------DHESAAVLGVRANVLTSRYYIEPCGAN-KSRLAHISRIDCRGRCPEWYNKLYGHLCAAEVVRIR 1120          

Query: 2864 FRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTD-TSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSS---SVSP-IRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKAR--IQMEFERIISLSKL----LRDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHG---FELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDH-DYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
             RW S   +++P  S   LE++  S  Q  +L+K ++LRLT++LE H  + K  +NW  PK + ++SK  D     VFG        R GQPLP  I  A++Y+R+   E  GIFR++G K+RI  L++  E + D   +     YDVAD+IK YFR LPE ++T+KL+ T + +  ++P +   +A+Q  +I LPDENR VLQ+LLYFLSD+   ++  QMT+ +LAVCL+PS+ H    +N+S     SP +  RK    PD +DL +  A  HCL  MI     LF++  E + ++R        + + L  L    L +  D+ +++   V+ L+ E + + K W  A               HG    EL YKK         +G + +  WR++ EI+AP S++L ++   R  WD ++   R+   + ++ ++ +    S  P  +R    +R    ++   + VLVS SVD                  HDN   +  +  VL    +        +SR+    R DLRG S +WY + + H+    +  ++
Sbjct:  525 LRWHSFQNSHRPSVSSASLEINRQSAAQLNLLQKFSLLRLTAILEKHTDTSKHGWNWVVPKFM-KRSKVPDYKDKHVFGVPPIVNVQRTGQPLPQSIQQAMRYLRSQCLEKVGIFRKSGVKSRIQALRQLNENSPDHVTYQGQSAYDVADLIKQYFRDLPEPVLTSKLTDTFLHVYQFVPAEQRLQAVQAAVILLPDENREVLQTLLYFLSDIAS-AQENQMTADSLAVCLAPSILH----LNASKKDGASPRLISRKGGAKPDHKDLSENMAATHCLSHMITECKKLFQIPHEMMLQSRNSYVAADAQPLPLHGLGVNALGEPVDYRAYLEDNVQCLLREASERSKGWHHA---------------HGPDNTELAYKK-------VGDG-HPMRIWRVSVEIEAPPSVVLQRVLRERHLWDEDLLHSRVIETLENNTEVFHYITDSMAPHPRRNFITLRRWCSDLPKGVCVLVSSSVD------------------HDNVQLEAGLRAVLLTSRMFIEPCGMGRSRLTHYCRADLRGRSPDWYNKVFGHLCAMEVARIR 1037          

Query: 2864 FRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTD-TSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSS---SVSP-IRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKAR--IQMEFERIISLSKL----LRDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHG---FELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDH-DYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
             RW S   +++P  S   LE++  S  Q  +L+K ++LRLT++LE H  + K  +NW  PK + ++SK  D     VFG        R GQPLP  I  A++Y+R+   E  GIFR++G K+RI  L++  E + D   +     YDVAD+IK YFR LPE ++T+KL+ T + +  ++P +   +A+Q  +I LPDENR VLQ+LLYFLSD+   ++  QMT+ +LAVCL+PS+ H    +N+S     SP +  RK    PD +DL +  A  HCL  MI     LF++  E + ++R        + + L  L    L +  D+ +++   V+ L+ E + + K W  A               HG    EL YKK         +G + +  WR++ EI+AP S++L ++   R  WD ++   R+   + ++ ++ +    S  P  +R    +R    ++   + VLVS SVD                  HDN   +  +  VL    +        +SR+    R DLRG S +WY + + H+    +  ++
Sbjct:  549 LRWHSFQNSHRPSVSSASLEINRQSAAQLNLLQKFSLLRLTAILEKHTDTSKHGWNWVVPKFM-KRSKVPDYKDKHVFGVPPIVNVQRTGQPLPQSIQQAMRYLRSQCLEKVGIFRKSGVKSRIQALRQLNENSPDHVTYQGQSAYDVADLIKQYFRDLPEPVLTSKLTDTFLHVYQFVPAEQRLQAVQAAVILLPDENREVLQTLLYFLSDIAS-AQENQMTADSLAVCLAPSILH----LNASKKDGASPRLISRKGGAKPDHKDLSENMAATHCLSHMITECKKLFQIPHEMMLQSRNSYVAADAQPLPLHGLGVNALGEPVDYRAYLEDNVQCLLREASERSKGWHHA---------------HGPDNTELAYKK-------VGDG-HPMRIWRVSVEIEAPPSVVLQRVLRERHLWDEDLLHSRVIETLENNTEVFHYITDSMAPHPRRNFITLRRWCSDLPKGVCVLVSSSVD------------------HDNVQLEAGLRAVLLTSRMFIEPCGMGRSRLTHYCRADLRGRSPDWYNKVFGHLCAMEVARIR 1061          

Query: 2864 FRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTD-TSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSS---SVSP-IRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKAR--IQMEFERIISLSKL----LRDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHG---FELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDH-DYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
             RW S   +++P  S   LE++  S  Q  +L+K ++LRLT++LE H  + K  +NW  PK + ++SK  D     VFG        R GQPLP  I  A++Y+R+   E  GIFR++G K+RI  L++  E + D   +     YDVAD+IK YFR LPE ++T+KL+ T + +  ++P +   +A+Q  +I LPDENR VLQ+LLYFLSD+   ++  QMT+ +LAVCL+PS+ H    +N+S     SP +  RK    PD +DL +  A  HCL  MI     LF++  E + ++R        + + L  L    L +  D+ +++   V+ L+ E + + K W  A               HG    EL YKK         +G + +  WR++ EI+AP S++L ++   R  WD ++   R+   + ++ ++ +    S  P  +R    +R    ++   + VLVS SVD                  HDN   +  +  VL    +        +SR+    R DLRG S +WY + + H+    +  ++
Sbjct:  549 LRWHSFQNSHRPSVSSASLEINRQSAAQLNLLQKFSLLRLTAILEKHTDTSKHGWNWVVPKFM-KRSKVPDYKDKHVFGVPPIVNVQRTGQPLPQSIQQAMRYLRSQCLEKVGIFRKSGVKSRIQALRQLNENSPDHVTYQGQSAYDVADLIKQYFRDLPEPVLTSKLTDTFLHVYQFVPAEQRLQAVQAAVILLPDENREVLQTLLYFLSDIAS-AQENQMTADSLAVCLAPSILH----LNASKKDGASPRLISRKGGAKPDHKDLSENMAATHCLSHMITECKKLFQIPHEMMLQSRNSYVAADAQPLPLHGLGVNALGEPVDYRAYLEDNVQCLLREASERSKGWHHA---------------HGPDNTELAYKK-------VGDG-HPMRIWRVSVEIEAPPSVVLQRVLRERHLWDEDLLHSRVIETLENNTEVFHYITDSMAPHPRRNFITLRRWCSDLPKGVCVLVSSSVD------------------HDNVQLEAGLRAVLLTSRMFIEPCGMGRSRLTHYCRADLRGRSPDWYNKVFGHLCAMEVARIR 1061          

Query: 2864 FRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRM---RKSIHG-PDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKAR-----IQMEFERIISLSKLL------RDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHV 4471
             RW S   +N+  +S   L+++  S  Q  +L+K ++LRLT+++E +  S K  + W  PK + +         +VFG  L     R GQPLP  +  AL+Y+R+   +  G+FR++G K+RI  L++  E + D  ++     YDVADM+K +FR LPE L+T+KL  T + I  Y+P++   +A+Q  I+ + DENR VLQ+LL FLSD+T   +  QMT  NLAVCL+PSLFH  +++   +++P  M   +K   G PD +DL +  A    L  MI     LF +  E + ++R      +++   I  L K         D   W +++ ++++ L+ ++  K K W S +                 EL YK       K  +G N +  WR++ E++AP S++L+++   R  WD+++   ++   +    ++    +   PP   R   ++R  + ++      LVS S++               HED         I V++ + ++E    S KSR+  + RVDL+G + EWY + + H+
Sbjct:  587 LRWPSFQISNRLSHSVASLQITSQSAAQLSLLQKFSLLRLTAIMEKYSMSNKHGWTWSVPKFMKRMKVPDYKDKNVFGVPLIVHVQRFGQPLPLGMQQALRYLRSQCLDQVGLFRKSGVKSRIQALRQMNESSPDDVNYEDQSAYDVADMVKQFFRDLPEPLLTSKLGETFLHIYQYVPKEQRLQAVQAAIMLMSDENREVLQTLLCFLSDVTSSVQENQMTPMNLAVCLAPSLFHL-NILKKDNLTPRAMHMQKKYATGRPDQKDLNENLAATQGLAHMITECNRLFEIPHEMVTQSRNSYVEAELQAPTIEELCKRQHPEDDGEDEGSWPAFMEARLQGLLKDSREKAKGWVSCQS------------TGNTELSYK-------KVGDG-NPLRRWRVSVEVEAPPSVVLNRVLRERHMWDVDLMNWKVSEVLDRQTEVFQYVLNCMPPHPSRDFVVLRSWRTDLPRGTCSLVSVSIE---------------HEDCPPVGGIRAI-VMESNYLLEPC-GSGKSRLTHICRVDLKGRTPEWYNKAFGHL 1099          

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFE-RIISLSKLL----RDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSN--PPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNV-INVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H FRW S   +++P  S   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         +VFG  L+    R GQPLP  I  A++Y+R+   +  G+FR++G K+RI  L++  E   D   +     YDVADM+K YFR LPE L+T+KLS T + I  Y+P++   +AI+  I+ LPDENR VLQ+LLYFLSD+       QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE        ME + R + L +L+        D+ S+++  ++ L+ +   KFK W +            SE     +L YK       K  EG   +  W+ T +I A    +L ++   +  WD ++   ++   + D  DI   + V N   P   R   ++R  + N+     VL   SV                  DHD      V +NVL    +IE   +S KS++ +L R DLRG   EWY + + HV    ++ ++
Sbjct:  528 HRFRWHSFQSSHRPSLSSASLQMNCQSVTQINLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRVKVPDYKDRNVFGVPLAINVQRTGQPLPQSIQLAMRYLRSQCLDQVGLFRKSGVKSRILALREISENNNDSLTYEGQSAYDVADMLKQYFRDLPEPLLTSKLSETFLQIYQYVPKEQRLQAIKAAIMLLPDENREVLQTLLYFLSDVAAAVDENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMHRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFKIPEEMSKCRNSYMEHDLRPVCLEELVNGNAEGLCDYQSYLQENIDVLLKDAKDKFKGWVNC---------STSEQA---DLSYK-------KVCEG-PPLRLWKATVDIPAQPEDVLHRLLREQHLWDEDLLDSKVIESLDDQTDI--YQYVQNYMAPHPARDFVVLRTWRTNLAKGACVLSCTSV------------------DHDRAPQLGVRVNVLMSRYLIEP-GSSGKSKLTYLCRADLRGHMPEWYNKVFGHVCAAEVVRIR 1042          

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFE-RIISLSKLL----RDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSN--PPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNV-INVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H FRW S   +++P  S   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         +VFG  L+    R GQPLP  I  A++Y+R+   +  G+FR++G K+RI  L++  E   D   +     YDVADM+K YFR LPE L+T+KLS T + I  Y+P++   +AI+  I+ LPDENR VLQ+LLYFLSD+       QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE        ME + R + L +L+        D+ S+++  ++ L+ +   KFK W +            SE     +L YK       K  EG   +  W+ T +I A    +L ++   +  WD ++   ++   + D  DI   + V N   P   R   ++R  + N+     VL   SV                  DHD      V +NVL    +IE   +S KS++ +L R DLRG   EWY + + HV    ++ ++
Sbjct:  545 HRFRWHSFQSSHRPSLSSASLQMNCQSVTQINLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRVKVPDYKDRNVFGVPLAINVQRTGQPLPQSIQLAMRYLRSQCLDQVGLFRKSGVKSRILALREISENNNDSLTYEGQSAYDVADMLKQYFRDLPEPLLTSKLSETFLQIYQYVPKEQRLQAIKAAIMLLPDENREVLQTLLYFLSDVAAAVDENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMHRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFKIPEEMSKCRNSYMEHDLRPVCLEELVNGNAEGLCDYQSYLQENIDVLLKDAKDKFKGWVNC---------STSEQA---DLSYK-------KVCEG-PPLRLWKATVDIPAQPEDVLHRLLREQHLWDEDLLDSKVIESLDDQTDI--YQYVQNYMAPHPARDFVVLRTWRTNLAKGACVLSCTSV------------------DHDRAPQLGVRVNVLMSRYLIEP-GSSGKSKLTYLCRADLRGHMPEWYNKVFGHVCAAEVVRIR 1059          

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFE-RIISLSKLL----RDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSN--PPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNV-INVLQDDVIIEYFPASQ-KSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H FRW S   +++P  S   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         +VFG  L+    R GQPLP  I  A++Y+R+   +  G+FR++G K+RI  L++  E   D   +     YDVADM+K YFR LPE L+T+KLS T + I  Y+P++   +AI+  I+ LPDENR VLQ+LLYFLSD+       QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE        ME + R + L +L+        D+ S+++  ++ L+ +   KFK W +            SE     +L YK       K  EG   +  W+ T +I A    +L ++   +  WD ++   ++   + D  DI   + V N   P   R   ++R  + N+     VL   SV                  DHD      V +NVL    +IE  P S  KS++ +L R DLRG   EWY + + HV    ++ ++
Sbjct:  556 HRFRWHSFQSSHRPSLSSASLQMNCQSVTQINLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRVKVPDYKDRNVFGVPLAINVQRTGQPLPQSIQLAMRYLRSQCLDQVGLFRKSGVKSRILALREISENNNDSLTYEGQSAYDVADMLKQYFRDLPEPLLTSKLSETFLQIYQYVPKEQRLQAIKAAIMLLPDENREVLQTLLYFLSDVAAAVDENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMHRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFKIPEEMSKCRNSYMEHDLRPVCLEELVNGNAEGLCDYQSYLQENIDVLLKDAKDKFKGWVNC---------STSEQA---DLSYK-------KVCEG-PPLRLWKATVDIPAQPEDVLHRLLREQHLWDEDLLDSKVIESLDDQTDI--YQYVQNYMAPHPARDFVVLRTWRTNLAKGACVLSCTSV------------------DHDRAPQLGVRVNVLMSRYLIE--PGSSGKSKLTYLCRADLRGHMPEWYNKVFGHVCAAEVVRIR 1070          

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFE-RIISLSKLL----RDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSN--PPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNV-INVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H FRW S   +++P  S   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         +VFG  L+    R GQPLP  I  A++Y+R+   +  G+FR++G K+RI  L++  E   D   +     YDVADM+K YFR LPE L+T+KLS T + I  Y+P++   +AI+  I+ LPDENR VLQ+LLYFLSD+       QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE        ME + R + L +L+        D+ S+++  ++ L+ +   KFK W +            SE     +L YK       K  EG   +  W+ T +I A    +L ++   +  WD ++   ++   + D  DI   + V N   P   R   ++R  + N+     VL   SV                  DHD      V +NVL    +IE   +S KS++ +L R DLRG   EWY + + HV    ++ ++
Sbjct:  525 HRFRWHSFQSSHRPSLSSASLQMNCQSVTQINLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRVKVPDYKDRNVFGVPLAINVQRTGQPLPQSIQLAMRYLRSQCLDQVGLFRKSGVKSRILALREISENNNDSLTYEGQSAYDVADMLKQYFRDLPEPLLTSKLSETFLQIYQYVPKEQRLQAIKAAIMLLPDENREVLQTLLYFLSDVAAAVDENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMHRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFKIPEEMSKCRNSYMEHDLRPVCLEELVNGNAEGLCDYQSYLQENIDVLLKDAKDKFKGWVNC---------STSEQA---DLSYK-------KVCEG-PPLRLWKATVDIPAQPEDVLHRLLREQHLWDEDLLDSKVIESLDDQTDI--YQYVQNYMAPHPARDFVVLRTWRTNLAKGACVLSCTSV------------------DHDRAPQLGVRVNVLMSRYLIEP-GSSGKSKLTYLCRADLRGHMPEWYNKVFGHVCAAEVVRIR 1039          

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFE-RIISLSKLL----RDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSN--PPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNV-INVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H FRW S   +++P  S   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         +VFG  L+    R GQPLP  I  A++Y+R+   +  G+FR++G K+RI  L++  E   D   +     YDVADM+K YFR LPE L+T+KLS T + I  Y+P++   +AI+  I+ LPDENR VLQ+LLYFLSD+       QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE        ME + R + L +L+        D+ S+++  ++ L+ +   KFK W +            SE     +L YK       K  EG   +  W+ T +I A    +L ++   +  WD ++   ++   + D  DI   + V N   P   R   ++R  + N+     VL   SV                  DHD      V +NVL    +IE   +S KS++ +L R DLRG   EWY + + HV    ++ ++
Sbjct:  556 HRFRWHSFQSSHRPSLSSASLQMNCQSVTQINLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRVKVPDYKDRNVFGVPLAINVQRTGQPLPQSIQLAMRYLRSQCLDQVGLFRKSGVKSRILALREISENNNDSLTYEGQSAYDVADMLKQYFRDLPEPLLTSKLSETFLQIYQYVPKEQRLQAIKAAIMLLPDENREVLQTLLYFLSDVAAAVDENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMHRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFKIPEEMSKCRNSYMEHDLRPVCLEELVNGNAEGLCDYQSYLQENIDVLLKDAKDKFKGWVNC---------STSEQA---DLSYK-------KVCEG-PPLRLWKATVDIPAQPEDVLHRLLREQHLWDEDLLDSKVIESLDDQTDI--YQYVQNYMAPHPARDFVVLRTWRTNLAKGACVLSCTSV------------------DHDRAPQLGVRVNVLMSRYLIEP-GSSGKSKLTYLCRADLRGHMPEWYNKVFGHVCAAEVVRIR 1070          

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKAR---IQMEFERII--SLSKLLRD-CNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVV-SNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVD-DNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H  RW S   +++P  +   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         SVFG  L+    R GQPLP  I  A++Y+R    +  G+FR++G K+RI  L++  E  +D  ++     YDVADM+K YFR LPE LMTNKLS T + I  Y+P+    +AI+  I+ LPDENR VLQ+LLYFLSD+T   K  QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE +++ R    + E + +   +L  L  D   D+  +++  V+ L  E   KFK W S            SE     EL YK       K SEG   +  WR T E+ A    IL ++   +  WD+++   ++  EI DS    Y  V  S  P   R   ++R  + N+      L+  SVD D +PV   +                  +NVL    +IE    S KS++ ++ R DLRG   EWY + + H+    ++ ++
Sbjct:  562 HRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRSGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAEDNVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEE-MSRCRNSYTEQELKPLTLEALGHLNSDQPADYRHFLQDCVDGLFKEVKEKFKGWVSY---------PTSEQA---ELSYK-------KVSEG-PPLRLWRSTIEVPAAPEEILKRLLKEQHLWDVDLLDSKVI-EILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPRGACALLLTSVDHDRAPVAGVR------------------VNVLLSRYLIEPC-GSGKSKLTYMCRADLRGHMPEWYSKSFGHLCAAEVVKIR 1076          

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKAR---IQMEFERII--SLSKLLRD-CNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVV-SNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVD-DNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H  RW S   +++P  +   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         SVFG  L+    R GQPLP  I  A++Y+R    +  G+FR++G K+RI  L++  E  +D  ++     YDVADM+K YFR LPE LMTNKLS T + I  Y+P+    +AI+  I+ LPDENR VLQ+LLYFLSD+T   K  QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE +++ R    + E + +   +L  L  D   D+  +++  V+ L  E   KFK W S            SE     EL YK       K SEG   +  WR T E+ A    IL ++   +  WD+++   ++  EI DS    Y  V  S  P   R   ++R  + N+      L+  SVD D +PV   +                  +NVL    +IE    S KS++ ++ R DLRG   EWY + + H+    ++ ++
Sbjct:  596 HRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRSGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAEDNVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEE-MSRCRNSYTEQELKPLTLEALGHLNSDQPADYRHFLQDCVDGLFKEVKEKFKGWVSY---------PTSEQA---ELSYK-------KVSEG-PPLRLWRSTIEVPAAPEEILKRLLKEQHLWDVDLLDSKVI-EILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPRGACALLLTSVDHDRAPVAGVR------------------VNVLLSRYLIEPC-GSGKSKLTYMCRADLRGHMPEWYSKSFGHLCAAEVVKIR 1110          

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKAR---IQMEFERII--SLSKLLRD-CNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVV-SNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVD-DNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H  RW S   +++P  +   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         SVFG  L+    R GQPLP  I  A++Y+R    +  G+FR++G K+RI  L++  E  +D  ++     YDVADM+K YFR LPE LMTNKLS T + I  Y+P+    +AI+  I+ LPDENR VLQ+LLYFLSD+T   K  QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE +++ R    + E + +   +L  L  D   D+  +++  V+ L  E   KFK W S            SE     EL YK       K SEG   +  WR T E+ A    IL ++   +  WD+++   ++  EI DS    Y  V  S  P   R   ++R  + N+      L+  SVD D +PV   +                  +NVL    +IE    S KS++ ++ R DLRG   EWY + + H+    ++ ++
Sbjct: 1013 HRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRSGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAEDNVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEE-MSRCRNSYTEQELKPLTLEALGHLNSDQPADYRHFLQDCVDGLFKEVKEKFKGWVSY---------PTSEQA---ELSYK-------KVSEG-PPLRLWRSTIEVPAAPEEILKRLLKEQHLWDVDLLDSKVI-EILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPRGACALLLTSVDHDRAPVAGVR------------------VNVLLSRYLIEPC-GSGKSKLTYMCRADLRGHMPEWYSKSFGHLCAAEVVKIR 1527          

Query: 2855 NHPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQ-MEFE-RIISL----SKLLRDCNDWYSWIRSKVEALINENNHKFKNW-TSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            N   RWSS   ++QP  S     +S  +  Q  +L++ ++LRLT+++E +  S K  + W  PK + +         +VFG  L     R GQPLP  I  AL+Y+R+   +  G+FR++G K+RI  L++  E   D   +     YDVADM+K +FR LPE L TNKLS T + I  Y+P++   +A+Q  I+ L DENR  LQ+LL FL D+       QMT  NLAVCL+PSLFH   +   SS   I+ + +   PD +DL +  A    L  MI     LF +  E + ++R   +E E  + SL    ++L      +++++   V+ L  E   KFK W T +  D   L   K    H  +L                     W+ + E++AP S++L+++   R  WD +    ++   +    +I    + S  P   R   ++R  + ++   +  LVS SV+               +E+         + V+    +IE    S KSR+  + R+DL+G S EWY + + H+    +  ++
Sbjct:  464 NRRLRWSSFQLSHQPQPSPATPHISSQTAAQLNLLQRFSLLRLTAIMEKYSMSNKHGWTWSVPKFMKRIKAPDYRDKAVFGVPLIVHVQRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPDNVSYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVPKEQRLQAVQAAILLLADENREALQTLLCFLHDVVNLVDENQMTPMNLAVCLAPSLFHLNLLKKESSPKVIQKKYATGKPDQKDLNENLAAAQGLAHMITECNRLFEVPHEMVAQSRDSYLEAEIHVPSLEDLGAQLAESGATFHTYLEHLVQGLQKEAKEKFKGWVTCSSPDNTDLAFKKVGDGHPLKL---------------------WKASVEVEAPPSVVLNRVLRERHLWDEDFVQWKVVERLDKQTEIYQYVLNSMVPHPSRDFLVLRTWKTDLPKGMCTLVSLSVE---------------YEEAQLMGGVRAV-VMDSQYLIEPC-GSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVTRIR 980          

Query: 2855 NHPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQ-MEFE-RIISL----SKLLRDCNDWYSWIRSKVEALINENNHKFKNW-TSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            N   RWSS   ++QP  S     +S  +  Q  +L++ ++LRLT+++E +  S K  + W  PK + +         +VFG  L     R GQPLP  I  AL+Y+R+   +  G+FR++G K+RI  L++  E   D   +     YDVADM+K +FR LPE L TNKLS T + I  Y+P++   +A+Q  I+ L DENR  LQ+LL FL D+       QMT  NLAVCL+PSLFH   +   SS   I+ + +   PD +DL +  A    L  MI     LF +  E + ++R   +E E  + SL    ++L      +++++   V+ L  E   KFK W T +  D   L   K    H  +L                     W+ + E++AP S++L+++   R  WD +    ++   +    +I    + S  P   R   ++R  + ++   +  LVS SV+               +E+         + V+    +IE    S KSR+  + R+DL+G S EWY + + H+    +  ++
Sbjct:  582 NRRLRWSSFQLSHQPQPSPATPHISSQTAAQLNLLQRFSLLRLTAIMEKYSMSNKHGWTWSVPKFMKRIKAPDYRDKAVFGVPLIVHVQRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPDNVSYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVPKEQRLQAVQAAILLLADENREALQTLLCFLHDVVNLVDENQMTPMNLAVCLAPSLFHLNLLKKESSPKVIQKKYATGKPDQKDLNENLAAAQGLAHMITECNRLFEVPHEMVAQSRDSYLEAEIHVPSLEDLGAQLAESGATFHTYLEHLVQGLQKEAKEKFKGWVTCSSPDNTDLAFKKVGDGHPLKL---------------------WKASVEVEAPPSVVLNRVLRERHLWDEDFVQWKVVERLDKQTEIYQYVLNSMVPHPSRDFLVLRTWKTDLPKGMCTLVSLSVE---------------YEEAQLMGGVRAV-VMDSQYLIEPC-GSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVTRIR 1098          

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFE-RIISLSKLLRDCN----DWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVV-SNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVD-DNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H  RW S   +++P  +   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         +VFG  L+    R GQPLP  I  A++Y+R    +  G+FR++G K+RI  L++  E T D  ++     YDVADM+K YFR LPE LMTNKLS T + I  Y+P+    +AI+  I+ LPDENR VLQ+LLYFLSD+T   K  QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE         E E + ++L  L R CN    D+  +++  V++L  E   KFK W S            SE     EL YK       K SEG   +  WR T E+ A    IL ++   +  WD+++   ++  EI DS    Y  V  S  P   R   ++R  + N+      L+  SVD D +PV   +                  +NVL    +IE    S KS++ ++ R DLRG   EWY + + H+    ++ ++
Sbjct:  582 HRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRNVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESTIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGRLCNDDSADYQHFLQDCVDSLFKEVKEKFKGWVSY---------STSEQA---ELSYK-------KVSEG-PPLRLWRATIEVPATPEEILKRLLKEQHLWDVDLLDSKVI-EILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVR------------------VNVLLARYLIEPC-GSGKSKLTYMCRADLRGHMPEWYTKSFGHLCAAEVVKIR 1096          

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFE-RIISLSKLLRDCN----DWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVV-SNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVD-DNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H  RW S   +++P  +   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         SVFG  L+    R GQPLP  I  A++Y+R    +  G+FR++G K+RI  L++  E  +D  ++     YDVADM+K YFR LPE LMTNKLS T + I  Y+P+    +AI+  I+ LPDENR VLQ+LLYFLS +T   K  QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE         E E + ++L  L    N    D+  +++  V+ L  E   KFK W S            SE     EL YK       K SEG   +  WR T E+ A    IL ++   +  WD+++   ++  EI DS    Y  V  S  P   R   ++R  + N+      L+  SVD D +PV   +                  +NVL    +IE    S KS++ ++ R DLRG   EWY + + H+    ++ ++
Sbjct:  561 HRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRSGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAEDYVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSHVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLSNDQPADYRHFLQDCVDGLFKEVKEKFKGWVSY---------PTSEQA---ELSYK-------KVSEG-PPLRLWRATIEVPAAPEEILKRLLKEQHLWDVDLLDSKVI-EILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPRGACALLFTSVDHDRAPVAGVR------------------VNVLLSRYLIEPC-GSGKSKLTYMCRADLRGHMPEWYTKSFGHLCAAEVVKIR 1075          

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKAR---IQMEFERII--SLSKLLRD-CNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVV-SNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVD-DNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H  RW S   +++P  +   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         SVFG  L+    R GQPLP  I  A++Y+R    +  G+FR++G K+RI  L++  E  +D  ++     YDVADM+K YFR LPE LMTNKLS T + I  Y+P+    +AI+  I+ LPDENR VLQ+LLYFLSD+T   K  QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE +++ R    + E + +   +L  L  D   D+  +++  V+ L  E   KFK W S            SE     +L YK       K SEG   +  WR T E+ A    IL ++   +  WD+++   ++  EI DS    Y  V  S  P   R   ++R  + N+      L+  SVD D +PV   +                  +NVL    +IE    S KS++ ++ R DLRG   EWY + + H+    ++ ++
Sbjct:  562 HRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRSGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAEDNVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEE-MSRCRNSYTEQELKPLTLEALGHLNSDQPADYRHFLQDCVDGLFKEVKEKFKGWVSY---------PTSEQA---DLSYK-------KVSEG-PPLRLWRSTIEVPAAPEEILKRLLKEQHLWDVDLLDSKVI-EILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPRGACALLLTSVDHDRAPVAGVR------------------VNVLLSRYLIEPC-GSGKSKLTYMCRADLRGHMPEWYSKSFGHLCAAEVVKIR 1076          

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFE-RIISLSKLLR----DCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVV-SNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVD-DNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H  RW S   +++P  +   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         SVFG  L+    R GQPLP  I  A++Y+R    +  G+FR++G K+RI  L++  E   D  ++     YDVADM+K YFR LPE LMTNKLS T + I  Y+P+    +AI+  I+ LPDENR VLQ+LLYFLSD+T   K  QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE         E E + ++L  L      D  D+  +++  V+ L  E   KFK W S            SE     EL YK       K SEG   +  WR   E+ A    IL ++   +  WD+++   ++  EI DS    Y  V  S  P   R   ++R  + N+      L+  SVD D +PV   +                  +NVL    +IE      KS++ ++ RVDLRG   EWY + + H+    ++ ++
Sbjct:  998 HRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSY---------STSEQA---ELSYK-------KVSEG-PPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVI-EILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVR------------------VNVLLSRYLIEPC-GPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIR 1512          

Query: 2858 HPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK-SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFE-RIISLSKLLR----DCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVV-SNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVD-DNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            H  RW S   +++P  +   L+++  S+ Q  +L+K ++L+LT+LLE + PS K  F+W  PK + +         +VFG  L+    R GQPLP  I  A++Y+R    +  G+FR++G K+RI  L++  E   D  ++     YDVADM+K YFR LPE LMTNKLS T + I   +P+    +A++  I+ LPDENR VLQ+LLYFLSD+T   K  QMT  NLAVCL+PSLFH   +   +S   +  RK S+  PD +DL +  A    L  MI     LF++ EE         E E + ++L  L R    +  D+  +++  V++L  E   KFK W S            SE     EL YK       K SEG   +  WR T E+ A    IL ++   +  WD+++   ++  EI DS    Y  V  S  P   R   ++R  + N+      L+  SVD D +PV   +                  +NVL    +IE    S KS++ ++ R DLRG   EWY + + H+    ++ ++
Sbjct:  561 HRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRNVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQCVPKDQRLQAMKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGRLRNDESADYQHFLQDCVDSLFKEVKEKFKGWVSY---------STSEQA---ELSYK-------KVSEG-PPLRLWRSTIEVPAMPEEILKRLLKEQHLWDVDLLDSKVI-EILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVR------------------VNVLLSRYLIEPC-GSGKSKLTYMCRADLRGHMPEWYTKSFGHLCAAEVVKIR 1075          

Query: 2864 FRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQ-KSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIP-EQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPH-VINSSSVSPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARI-QMEFERIISLSKLL-------RDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            FRWSS AR+++P    R+++++ +S+ Q  +LK  A L L  +++   P  KS  +W  PK L + K     + T+VFG  L+  Q R GQPLPP I H ++ +R  G  + GIFRR GGKAR++ LK  I+   DM DFS+ QPYD+AD++K Y R LPECL+T KLS TL+ + T++P +Q    A+Q  ++ LPDENR VLQSLLYFL D  +++ TTQM + NLAVCL+PSLF+ PH     S +SP R R++   PDPRDL+D KA   C+ FMI H   LF +SEE   +A    +E     +L  L        R C   ++++ +  + +  E +     WT                  G E F KK +   DK       +  W+    ++A  + IL++I   +  WD ++    +   I D+ D+    + S P Q  R+  ++R   R+   + + L + SV                              +L +D +IE       SR+  LSRVDLRG S EWY R W H + R+L+HLK
Sbjct:  130 FRWSSFARSHRPSIQVREMQIAAMSIAQMQVLKNAAFLELNKVMQEFCPPNKSLLSWFLPKFLRRAKPPIPPSKTAVFGVPLTTVQMRCGQPLPPCIVHMMRQLRQSGVSAHGIFRRTGGKARVSSLKAEIDAQPDMRDFSQCQPYDLADLVKMYLRELPECLVTTKLSPTLMDLFTFVPSDQLRLLALQCAMLLLPDENREVLQSLLYFLKDFAENADTTQMNASNLAVCLAPSLFYFPHETPTGSGLSPRRFRRATGVPDPRDLQDHKAATACVTFMITHCHQLFTVSEELYRQAAFSAVELAEPPALDSLAPVDASQRRHC---FAFVDNHAQMVGRECSEGAAKWTPFSSRC------------GVETFCKKLD---DKC-----PLRLWKAVMNVEADPTRILNRIVQDKASWDPDVLNSELVEMIDDNSDVTRFTLTSPPAQPAREQCVLRA-WRSAGSHSHCLYTASVRLPP------------------TPLTLPTLILNEDWLIEAC-GPGNSRVTLLSRVDLRGHSLEWYNRTWGHSIARQLVHLK 642          

Query: 2864 FRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQ-KSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIP-EQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPH-VINSSSVSPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARI-QMEFERIISLSKLL-------RDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHL 4495
            FRWSS AR+++P    R+++++ +S+ Q  +LK  A L L  +++   P  KS  +W  PK L + K     + T+VFG  L+  Q R GQPLPP I H ++ +R  G  + GIFRR GGKAR++ LK  I+   DM DFS+ QPYD+AD++K Y R LPECL+T KLS TL+ + T++P +Q    A+Q  ++ LPDENR VLQSLLYFL D  +++ TTQM + NLAVCL+PSLF+ PH     S +SP R R++   PDPRDL+D KA   C+ FMI H   LF +SEE   +A    +E     +L  L        R C   ++++ +  + +  E +     WT                  G E F KK +   DK       +  W+    ++A  + IL++I   +  WD ++    +   I D+ D+    + S P Q  R+  ++R   R+   + + L + SV                              +L +D +IE       SR+  LSRVDLRG S EWY R W H + R+L+HL
Sbjct:  130 FRWSSFARSHRPSIQVREMQIAAMSIAQMQVLKNAAFLELNKVMQEFCPPNKSLLSWFLPKFLRRAKPPIPPSKTAVFGVPLTTVQMRCGQPLPPCIVHMMRQLRQSGVSAHGIFRRTGGKARVSSLKAEIDAQPDMRDFSQCQPYDLADLVKMYLRELPECLVTTKLSPTLMDLFTFVPSDQLRLLALQCAMLLLPDENREVLQSLLYFLKDFAENADTTQMNASNLAVCLAPSLFYFPHETPTGSGLSPRRFRRATGVPDPRDLQDHKAATACVTFMITHCHQLFTVSEELYRQAAFSAVELAEPPALDSLAPVDASQRRHC---FAFVDNHAQMVGRECSEGAAKWTPFSSRC------------GVETFCKKLD---DKC-----PLRLWKAVMNVEADPTRILNRIVQDKASWDPDVLNSELVEMIDDNSDVTRFTLTSPPAQPAREQCVLRA-WRSAGSHSHCLYTASVRLPP------------------TPLTLPTLILNEDWLIEAC-GPGNSRVTLLSRVDLRGHSLEWYNRTWGHSIARQLVHL 641          

Query: 2864 FRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQ-KSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIP-EQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPH-VINSSSVSPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARI-QMEFERIISLSKLL-------RDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHL 4495
            FRWSS AR+++P    R+++++ +S+ Q  +LK  A L L  +++   P  KS  +W  PK L + K     + T+VFG  L+  Q R GQPLPP I H ++ +R  G  + GIFRR GGKAR++ LK  I+   DM DFS+ QPYD+AD++K Y R LPECL+T KLS TL+ + T++P +Q    A+Q  ++ LPDENR VLQSLLYFL D  +++ TTQM + NLAVCL+PSLF+ PH     S +SP R R++   PDPRDL+D KA   C+ FMI H   LF +SEE   +A    +E     +L  L        R C   ++++ +  + +  E +     WT                  G E F KK +   DK       +  W+    ++A  + IL++I   +  WD ++    +   I D+ D+    + S P Q  R+  ++R   R+   + + L + SV                              +L +D +IE       SR+  LSRVDLRG S EWY R W H + R+L+HL
Sbjct:  130 FRWSSFARSHRPSIQVREMQIAAMSIAQMQVLKNAAFLELNKVMQEFCPPNKSLLSWFLPKFLRRAKPPIPPSKTAVFGVPLTTVQMRCGQPLPPCIVHMMRQLRQSGVSAHGIFRRTGGKARVSSLKAEIDAQPDMRDFSQCQPYDLADLVKMYLRELPECLVTTKLSPTLMDLFTFVPSDQLRLLALQCAMLLLPDENREVLQSLLYFLKDFAENADTTQMNASNLAVCLAPSLFYFPHETPTGSGLSPRRFRRATGVPDPRDLQDHKAATACVTFMITHCHQLFTVSEELYRQAAFSAVELAEPPALDSLAPVDASQRRHC---FAFVDNHAQMVGRECSEGAAKWTPFSSRC------------GVETFCKKLD---DKC-----PLRLWKAVINVEADPTRILNRIVQDKASWDPDVLNSELVEMIDDNSDVTRFTLTSPPAQPAREQCVLRA-WRSAGSHSHCLYTASVRLPP------------------TPLTLPTLILNEDWLIEAC-GPGNSRVTLLSRVDLRGHSLEWYNRTWGHSIARQLVHL 641          

Query: 2864 FRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQ-KSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIP-EQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPH-VINSSSVSPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARI-QMEFERIISLSKLL-------RDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            FRWSS AR+++P    R+++++ +S+ Q  +LK  A L L  +++   P  KS  +W  PK L + K     + T+VFG  L+  Q R GQPLPP I H ++ +R  G  + GIFRR GGKAR++ LK  I+   DM DFS+ QPYD+AD++K Y R LPECL+T KLS TL+ + T++P +Q    A+Q  ++ LPDENR VLQSLLYFL D  +++ TTQM + NLAVCL+PSLF+ PH     S +SP R R++   PDPRDL+D KA   C+ FMI H   LF +SEE   +A    +E     +L  L        R C   ++++ +  + +  E +     WT                  G E F KK +   DK       +  W+    ++A  + IL++I   +  WD ++    +   I D+ D+    + S P Q  R+  ++R   R+   + + L + SV                              +L +D +IE       SR+  LSRVDLRG S EWY R W H + R+L+HLK
Sbjct:  559 FRWSSFARSHRPSIQVREMQIAAMSIAQMQVLKNAAFLELNKVMQEFCPPNKSLLSWFLPKFLRRAKPPIPPSKTAVFGVPLTTVQMRCGQPLPPCIVHMMRQLRQSGVSAHGIFRRTGGKARVSSLKAEIDAQPDMRDFSQCQPYDLADLVKMYLRELPECLVTTKLSPTLMDLFTFVPSDQLRLLALQCAMLLLPDENREVLQSLLYFLKDFAENADTTQMNASNLAVCLAPSLFYFPHETPTGSGLSPRRFRRATGVPDPRDLQDHKAATACVTFMITHCHQLFTVSEELYRQAAFSAVELAEPPALDSLAPVDASQRRHC---FAFVDNHAQMVGRECSEGAAKWTPFSSRC------------GVETFCKKLD---DKC-----PLRLWKAVMNVEADPTRILNRIVQDKASWDPDVLNSELVEMIDDNSDVTRFTLTSPPAQPAREQCVLRA-WRSAGSHSHCLYTASVRLPP------------------TPLTLPTLILNEDWLIEAC-GPGNSRVTLLSRVDLRGHSLEWYNRTWGHSIARQLVHLK 1071          

Query: 3089 VFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFH----SPHVINSSSVSPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFERIISLSKLLRDCNDWYSWIRSKVEALINE-NNHKFKNWTSARKDILKLHNDKS---EMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEI-DAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVIN--------VLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            VFG SLS WQ R+G PLPP I H + ++   G  + G+FRR GGK+RI  L++ IE+      F  WQPYD+AD++K +FR LPECL T+KL++ L+++   +P     + ++W++I+LPDENR+VLQ LLY L+ L++HS  T+MT+ NLAVC +PSL+     SP      S+SP R+R++  GPDP+DL DQ+A    L  MI+ AP+LF++S   ++ + +           + L    DW  WI+S +  L+ E ++ K K W +  +DI+K +N  S   E++  FE+ YKK    S +     N++  WR +  I +    +IL++   +R  WD EI  + I  +ISD VD+C + + +  PQ Q  + L+RG Q  ++     ++S+S+  NS  ++        H  H     ++ IN        V +D V I     SQ  R+  LSRVDL+G+  +WY  QW H L RRL HL+
Sbjct: 1006 VFGQSLSSWQRRLGYPLPPAIIHMMDHLELNGTTAHGLFRRPGGKSRILALREEIERDLCWRKFDDWQPYDIADLLKQFFRELPECLFTSKLATVLVNVYICVPNSIQIDLLRWILISLPDENRIVLQKLLYLLNHLSRHSDVTEMTANNLAVCFAPSLYRLIKPSPLSNQGVSLSPRRLRRTTSGPDPKDLADQRAAQLSLSAMINLAPNLFQISSSLLSHSTLLTSLTPFAQDLETLIPNGDWPQWIQSSLSDLLRECSSSKSKGWNTINRDIMKYYNVDSNYNELMDNFEIHYKK-MPNSTELKTTPNTLRLWRCSLYIPEINPRVILNRFVENRSSWDPEITEMTIVDQISDCVDLCELHLSNIYPQPQCHLHLLRGIQYTLEDGSCAMLSESI-CNSAFSN-------IHTTHSLSTTFSSINSTINVLGHVYEDHVYIRPDNNSQGCRVYLLSRVDLKGYGPDWYMNQWGHTLYRRLFHLR 1483          

Query: 2864 FRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSS---SVSP-IRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKAR-----------------IQMEFERIISLSKLLRDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDH-DYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
             RW S   +++P  S    E++  S  Q  +L+K ++LRLT++LE H    K  ++W  PK + +          VFG        R GQPLP  I  A++Y+R+   E  GIFR++G K+RI  L++  E + D   +     YDVAD++K YFR LPE ++T+KL+ T + I  ++PE    +A+Q  ++ LPDENR VLQ+LLYFLSD+   ++  QMT+ NLAVCL+PS+ H    +N+S     SP +  RK    PD +DL +  A   CL  MI     LF++  E + ++R                 +    ER+           D+ ++++  V+ L+ E   K K W S                   EL YK       K  +G + I  WRI+AE++AP  ++L ++   R  WD ++   R+   + ++ ++ +    S  P  +R   ++R    ++     +LVS SV                  +HDN   +  +  VL    I+       +SR+    R DLRG S +WY + + H+    +  ++
Sbjct:  517 LRWHSFQNSHRPSVSSASQEINRQSAAQLNLLQKYSLLRLTAILEKHCDMGKHGWSWAVPKFMKRSKSPDYKDKHVFGVPPFINVQRTGQPLPQSIQQAMRYLRSQCLEKVGIFRKSGVKSRIQALRQLNENSPDHVTYQGQSAYDVADLLKQYFRDLPEPVLTSKLTETFLHIYQFVPECQRLQAVQAAVVLLPDENREVLQTLLYFLSDIAS-AQENQMTAENLAVCLAPSILH----LNTSKRDGTSPRLISRKGGAKPDHKDLSENMAATQCLCHMITECKKLFQIPHEMMLQSRNSYVAADAQPLPLHGFGVNARGERV-----------DYRAYLQDNVQCLLREAAEKSKGWHSVNGP------------DNTELSYK-------KVGDG-HPIRLWRISAEMEAPPPVVLQRVLRERHLWDEDLLHSRVIETLENNTEVFHYITDSMAPHPRRDFVVLRRWSSDLQRGACILVSSSV------------------EHDNVQLEAGLRAVLLTSRILIEPCGMGRSRLIHYCRADLRGRSPDWYNKVFGHLCAAEVARIR 1029          

Query: 2864 FRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSS---SVSP-IRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKAR-----------------IQMEFERIISLSKLLRDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDH-DYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
             RW S   +++P  S    E++  S  Q  +L+K ++LRLT++LE H    K  ++W  PK + +          VFG        R GQPLP  I  A++Y+R+   E  GIFR++G K+RI  L++  E + D   +     YDVAD++K YFR LPE ++T+KL+ T + I  ++PE    +A+Q  ++ LPDENR VLQ+LLYFLSD+   ++  QMT+ NLAVCL+PS+ H    +N+S     SP +  RK    PD +DL +  A   CL  MI     LF++  E + ++R                 +    ER+           D+ ++++  V+ L+ E   K K W S                   EL YK       K  +G + I  WRI+AE++AP  ++L ++   R  WD ++   R+   + ++ ++ +    S  P  +R   ++R    ++     +LVS SV                  +HDN   +  +  VL    I+       +SR+    R DLRG S +WY + + H+    +  ++
Sbjct:  541 LRWHSFQNSHRPSVSSASQEINRQSAAQLNLLQKYSLLRLTAILEKHCDMGKHGWSWAVPKFMKRSKSPDYKDKHVFGVPPFINVQRTGQPLPQSIQQAMRYLRSQCLEKVGIFRKSGVKSRIQALRQLNENSPDHVTYQGQSAYDVADLLKQYFRDLPEPVLTSKLTETFLHIYQFVPECQRLQAVQAAVVLLPDENREVLQTLLYFLSDIAS-AQENQMTAENLAVCLAPSILH----LNTSKRDGTSPRLISRKGGAKPDHKDLSENMAATQCLCHMITECKKLFQIPHEMMLQSRNSYVAADAQPLPLHGFGVNARGERV-----------DYRAYLQDNVQCLLREAAEKSKGWHSVNGP------------DNTELSYK-------KVGDG-HPIRLWRISAEMEAPPPVVLQRVLRERHLWDEDLLHSRVIETLENNTEVFHYITDSMAPHPRRDFVVLRRWSSDLQRGACILVSSSV------------------EHDNVQLEAGLRAVLLTSRILIEPCGMGRSRLIHYCRADLRGRSPDWYNKVFGHLCAAEVARIR 1053          

Query: 2864 FRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSS---SVSP-IRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKAR-----------------IQMEFERIISLSKLLRDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDH-DYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
             RW S   +++P  S    E++  S  Q  +L+K ++LRLT++LE H    K  ++W  PK + +          VFG        R GQPLP  I  A++Y+R+   E  GIFR++G K+RI  L++  E + D   +     YDVAD++K YFR LPE ++T+KL+ T + I  ++PE    +A+Q  ++ LPDENR VLQ+LLYFLSD+   ++  QMT+ NLAVCL+PS+ H    +N+S     SP +  RK    PD +DL +  A   CL  MI     LF++  E + ++R                 +    ER+           D+ ++++  V+ L+ E   K K W S                   EL YK       K  +G + I  WRI+AE++AP  ++L ++   R  WD ++   R+   + ++ ++ +    S  P  +R   ++R    ++     +LVS SV                  +HDN   +  +  VL    I+       +SR+    R DLRG S +WY + + H+    +  ++
Sbjct:  538 LRWHSFQNSHRPSVSSASQEINRQSAAQLNLLQKYSLLRLTAILEKHCDMGKHGWSWAVPKFMKRSKSPDYKDKHVFGVPPFINVQRTGQPLPQSIQQAMRYLRSQCLEKVGIFRKSGVKSRIQALRQLNENSPDHVTYQGQSAYDVADLLKQYFRDLPEPVLTSKLTETFLHIYQFVPECQRLQAVQAAVVLLPDENREVLQTLLYFLSDIAS-AQENQMTAENLAVCLAPSILH----LNTSKRDGTSPRLISRKGGAKPDHKDLSENMAATQCLCHMITECKKLFQIPHEMMLQSRNSYVAADAQPLPLHGFGVNARGERV-----------DYRAYLQDNVQCLLREAAEKSKGWHSVNGP------------DNTELSYK-------KVGDG-HPIRLWRISAEMEAPPPVVLQRVLRERHLWDEDLLHSRVIETLENNTEVFHYITDSMAPHPRRDFVVLRRWSSDLQRGACILVSSSV------------------EHDNVQLEAGLRAVLLTSRILIEPCGMGRSRLIHYCRADLRGRSPDWYNKVFGHLCAAEVARIR 1050          

Query: 2864 FRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSS---SVSP-IRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKAR-----------------IQMEFERIISLSKLLRDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDH-DYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
             RW S   +++P  S    E++  S  Q  +L+K ++LRLT++LE H    K  ++W  PK + +          VFG        R GQPLP  I  A++Y+R+   E  GIFR++G K+RI  L++  E + D   +     YDVAD++K YFR LPE ++T+KL+ T + I  ++PE    +A+Q  ++ LPDENR VLQ+LLYFLSD+   ++  QMT+ NLAVCL+PS+ H    +N+S     SP +  RK    PD +DL +  A   CL  MI     LF++  E + ++R                 +    ER+           D+ ++++  V+ L+ E   K K W S                   EL YK       K  +G + I  WRI+AE++AP  ++L ++   R  WD ++   R+   + ++ ++ +    S  P  +R   ++R    ++     +LVS SV                  +HDN   +  +  VL    I+       +SR+    R DLRG S +WY + + H+    +  ++
Sbjct:  531 LRWHSFQNSHRPSVSSASQEINRQSAAQLNLLQKYSLLRLTAILEKHCDMGKHGWSWAVPKFMKRSKSPDYKDKHVFGVPPFINVQRTGQPLPQSIQQAMRYLRSQCLEKVGIFRKSGVKSRIQALRQLNENSPDHVTYQGQSAYDVADLLKQYFRDLPEPVLTSKLTETFLHIYQFVPECQRLQAVQAAVVLLPDENREVLQTLLYFLSDIAS-AQENQMTAENLAVCLAPSILH----LNTSKRDGTSPRLISRKGGAKPDHKDLSENMAATQCLCHMITECKKLFQIPHEMMLQSRNSYVAADAQPLPLHGFGVNARGERV-----------DYRAYLQDNVQCLLREAAEKSKGWHSVNGP------------DNTELSYK-------KVGDG-HPIRLWRISAEMEAPPPVVLQRVLRERHLWDEDLLHSRVIETLENNTEVFHYITDSMAPHPRRDFVVLRRWSSDLQRGACILVSSSV------------------EHDNVQLEAGLRAVLLTSRILIEPCGMGRSRLIHYCRADLRGRSPDWYNKVFGHLCAAEVARIR 1043          

Query: 2864 FRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSP--IRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFERIISLSKLLRDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
             RW S   +N+   S   L++S  S +Q  +L+K ++LRLT+++E +  S K  + W  PK + +         SVF   L     R GQPLP  +  AL+Y+R+   +  G+FR++G K+RI  L++  + + +  D+     YDVADM+K +FR LPE L+T+KL  T + I  Y+P++   +A+Q  I+ + DENR VLQ+LL FLSD+T   +  QMT  NLAVCL+PSLFH  +++ + ++SP  I+ + +   PD +DL +  A  H L  MI     LF + +E + ++R       ++   + + +   +   ++ +++ L+ E   K K W  AR +I           +  EL ++K    S         +  WR++ E++AP  ++L+++   R  WD  +   ++   +    ++    + S  P   R   ++R  + ++     VLVS S+D               HED         + VL+   ++E    S KSR+  + RVDL+G S EWY + + H+    +  ++
Sbjct:  530 LRWPSFRMSNRLSQSGACLQISSQSASQLSLLQKFSLLRLTAIMEKYSISNKHGWTWSVPKFMKRMKGPEYKDKSVFAVPLILHVQRYGQPLPLCLQLALRYLRSQCLDQVGLFRKSGVKSRILALRQMCDSSPESVDYEDQCAYDVADMVKQFFRDLPEPLLTSKLGETFLHIYQYVPKEQRLQAVQAAIMLMADENREVLQTLLCFLSDVTSSVEENQMTPMNLAVCLAPSLFHL-NIMKNDNLSPRAIQKKYATGRPDQKDLNENLAATHGLAHMITECNRLFEVPKEMVTQSRNSYMEAELLEEEEEVEEEGSYRCHLQRQIQNLLKEARDKTKCWV-ARPNI-----------NNVELSFRKVGDGS--------PLRRWRVSVEVEAPPCVVLNRVLRERHLWDSNLLQGKVLETLDKQTEVYQYAINSMAPHPSRDFVVLRTWRTDMPKGACVLVSVSID---------------HEDSMPMAGVRGV-VLESQYLLEQC-GSGKSRLTHICRVDLKGKSLEWYNKAFGHLCAAEVASIR 1038          

Query: 3086 SVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRKSIHG-PDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQ-MEFE-RIISLSKLLRDCNDWY----SWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            SVFG  L     R GQPLP  I  A++Y+R+   +  G+FR++G K+RI  L++  E   +  ++     YDVADM+K YFR LPE + T+KL+ T + I  Y+P++   +A+Q   + LPDENR  LQ+LLYFLSD+       QM+S NLAVCL+PSLFH   V   +S S +R RK   G PD +DL +  A    L  MI     LF++ EE +++ +   ME + + +SL++L     +      + + S ++ L+ E   KFK W +            S +    E+ YK       K  +G + +  W+ T E++AP   +L +I++ R  WD ++   ++   +  + ++ Y  + S  P   R   ++R  + ++     VLV+ SV+               HE+     +   + VL    +IE   A+ +SR+  + R+D RG S EWY + + H+   ++  ++
Sbjct:   24 SVFGVPLLLNVQRTGQPLPQSIQQAMRYLRSQCLDQVGLFRKSGVKSRIQALREMNESGAESVNYEGQSAYDVADMLKQYFRDLPEPMFTSKLADTFLQIYQYVPKEQQLQALQAGTMLLPDENREALQTLLYFLSDVAAAVGENQMSSVNLAVCLAPSLFHLNTVKRDNSTSRVRQRKYSTGKPDQKDLSENLAAIQGLAHMIAECKKLFKIPEEMVSQCQSSYMEHDTQPMSLAELGAPVTNGGGPPPAHLESCIQGLLKEARDKFKGWVTC-----------SSLESSTEVAYK-------KVGDG-HLLRLWKTTVEVEAPPPRVLQRIRSERHLWDEDLLQWKVVETLDPNTEVFYYVLNSMAPHPARDYLVLRSWRTDLPKGSCVLVATSVE---------------HEEVPCVGEARAV-VLASRYLIEPLGAN-RSRLTHVCRIDTRGRSLEWYNKVFGHLCASKVAMIR 465          

Query: 3059 KSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQD--MTDFSKWQPYDVADMIKSYFRSLPECLM-TNKLSSTLISIKTYIPEQNWFEA---IQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSV 3601
            +S+FTD    +F  +L  +    GQ +P V+   +++I   G +  GIFR +G +  + ++K A E+ +D  + D        VA ++K YFR L   L    K    ++ +K     +N +E    I+ +I+ LP    +V++ LL FL+ L++ S    M  YNLA+C  P+L   P   +  SV
Sbjct:  334 RSQFTD---KLFNGNLETFIQDTGQVIPLVVESCVRFINLYGLQHQGIFRVSGSQVEVNDIKNAFERGEDPLVEDEDSHDINSVAGVLKLYFRGLENSLFPKEKFHDLVMCVKM----ENLYERAAHIRKIILTLPRSTIVVMRYLLAFLNHLSQFSDENMMDPYNLAICFGPTLMPVPEGHDQVSV 513          

Query: 3053 SQKSKFTDT-STSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMI-KSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLF-HSPHVINSSSVSPI 3610
            +Q S   D  +T  FG  L       GQ +P V+   + Y++  G +++GIFRR+     + E ++   + Q + DF       +A +I K++ R LPE L+T  L   ++S++  + +     A+  ++  LP+ENR VL  LL FL  ++ HS   +M+  NLA+   P+L       +N ++++P+
Sbjct:  182 AQASVAVDVPATQQFGVGLKRLAENSGQLIPLVVRDTVAYLKEHGLQTEGIFRRSASTQALRETQERYNRGQPV-DFQALGDVHLAAVILKTFLRELPEPLLTFSLFPYIVSVQG-LEKDARGAAVVEMVKKLPEENRAVLHHLLDFLKLVSPHSGVNKMSGENLAIVFGPNLVWERERSLNLATMAPV 368          

Query: 3089 VFGASLSYWQGRI----GQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPS 3562
            +FGA+L     R     G PLP V    + YI   G + +GI+R +G K+++ ELK AI   ++  +   + P+ VA ++K Y R LPE L+T +L   +    +    ++     + ++  LP  NR +L  L+  +  +  H    +M    +++ L P+
Sbjct:  197 IFGATLEEAVHRTALYDGVPLPAVCRECIDYIERNGLKCEGIYRVSGIKSKVDELK-AIYDREESPNLEDYDPHTVASVLKQYLRELPESLLTRELHPKIEEACSRPLVEDRLAECKRLLAELPKFNRHLLSWLMVHMDHVVLHESDNKMNVQGISIVLHPT 357          

Query: 3188 ESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSP 3607
            +++GIFR+ G  +R+ ELK  +E+ +     +     DVA ++K + R   E L+  +L S+L   +     +    A   + + +P      L+ L+ FL  + + ++  +MT+ NLAV  +P+L H       +S++P
Sbjct:   14 DTEGIFRKPGSLSRMRELKARLERGEAC--LAGATVNDVAGLLKQHLREAAEPLVPRELHSSLRRAQQLATAEERTRATLLLCLLMPPATAHTLRFLMTFLHSVAERAEDNKMTATNLAVVFTPTLMHGGR---GASLTP 148          

Query: 3137 LPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMT-DFSKW---QPYDVADMIKSYFRSLPECLMTNKL-----SSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSP 3577
            +P VI  + KY++    ++ GIFR AG   R+ EL+    K  D    F  W     +D+A ++K Y  SL E L+   L     +  L + K    ++   +  + + + LP +NR ++  L   L+   ++ K   M++ NLA  + PSL   P
Sbjct:   75 IPVVIAKSGKYLKENALDTTGIFRIAGSNKRVRELQAVFSKPPDYGRKFEGWCDFNVHDIATLLKRYLNSLSEPLVPLALYDIFRNPILENPKINEHKEQIIKDYEDIYMLLPQQNRHLILYLAALLNLFARNEKKNLMSASNLAAIVQPSLLSHP 230          

Query: 3137 LPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQP---------YDVADMIKSYFRSLPECLMTNKLSSTL---ISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSL 3565
            +P ++   +  I   G + +GI+R++     +++LK+ I+K  D  + S   P         Y V  ++K++F SLP+ ++   LSS +   + I+     +N+   +   I NLPD     L++L++ L  +  H    +M    L +   P++
Sbjct:  485 VPAIVRQCIYVIDKFGLDQEGIYRKSANVLDVSKLKEEIDK--DPANISMILPSKPHSDSDIYLVGSLLKTFFASLPDSVLPKALSSEIKVCLQIEDPTTRKNFMHGL---IYNLPDAQYWTLRALVFHLKRVLAHEAQNRMNLRALCIIWGPTI 634          

Query: 2912 RDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSY----WQ-------GRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKT-QDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLS-----DLTKHSKTTQMTSYNLAVCLSPSLFHSPH 3580
            R + LS L+  Q +         L S++ S+       F W   K++         + +VFGA L      W        G +   +P +I   +  +R +    +GIFR+ G   R+ EL   I+    +  DFSK     ++ ++K + R LP+ +++  L    I       E      I  +   LP  NR +L++LL FL         ++   ++M  +NL+  ++P++ +  H
Sbjct:  669 RAISLSLLAGKQLISKTDPNYTSLVSMVFSNEKQVTGSF-WNRMKIMMSMEPKKPITKTVFGAPLDVLCEKWGVDSDLGVGPVKIRIPIIIDELISSLRQMDMSVEGIFRKNGNIRRLRELTANIDSNPTEAPDFSKENAIQLSALLKKFIRELPQPILSTDLYELWIKAAKIDLEDEKQRVILLIYSLLPTYNRNLLEALLSFLHWTSSFSYIENEMGSKMDIHNLSTVITPNILYLRH 907          

Query: 3089 VFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKT---YIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQ-MEFERIISLSKLLRD----CNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWY 4450
            VFG  +S    R GQPLP  I  A+ Y++    ES GIFR++GGK RI  LK  +E   + TDF    PYD+ADM+K YFR LP+ ++T+KL+ T I+I T   YIP +   EA+Q  I+ +PDENR  LQ+LL FL+++ ++S   QM   NL VC +PSLFH        S +P R +++      ++L D  A H CL  MI     LF + E+T+ K+R   +E    ++L +L R      +D+ ++I S +  ++ E   KFK W            + S      E+ YK       K  +G   +  WR   EIDA    +L +I + R  WD E+    +  +I + +D+ Y    S   Q +R   ++R  + N+      LV  S+  + P     P  Q T              +L    +IE   A  +SR+  ++R+D +G +S +Y
Sbjct:   17 VFGVPMSVVLQRSGQPLPRPILCAINYLQRTCVESVGIFRKSGGKQRINNLKDMMEDNPEHTDFEGMSPYDLADMLKQYFRDLPDPILTSKLAETFITIHTCKYYIPAELRVEAMQAAILLMPDENREALQTLLLFLNEVAENSAVNQMNEKNLGVCFAPSLFHLCGTKEDPS-APKRQKRTPMIKASKELTDNLAAHECLTQMIAQVDKLFLVPEDTMMKSRFSYIEQSEPVTLEQLGRSKSNPLDDYRTYIESCINGILKEAREKFKGWV-----------NHSWHESSVEVSYK-------KVRDGC-PLRLWRGVIEIDASPEDVLKRIVDERHLWDEELEAWDVLEKIDEDMDVFYYVTRSMILQPKRIHVVLRARRTNLAHGACALVCTSI--SHPSAPMTPGVQAT--------------LLAQRYLIEPLEAG-RSRLTHITRLDQKGRASVYY 441          

Query: 3023 QFNWKFPKLLSQKSKFTDT-STSVFGASLSYWQGR-IGQ----PLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARI 3751
            +   K PK  +   + TD    +VFGA L       +G+     +P  +  + K++R     ++G+FR++G   R   LK+ IE  +++   S  QP+DVA ++K +FR L E L+TN    + I       +    +A+ ++ + LP  +   L+  + FL++   HS+ ++M   NLA+ L+P+L H+    NSSS               R L+DQ      +K ++ +A SL  + ++   +A++
Sbjct:   23 RLGLKVPKYKAVFKQGTDVREGAVFGALLDNVPSENVGENYYCSVPKFLVDSAKFLRQ-HMNTEGLFRKSGSVQRQKLLKERIELGEEI---STAQPHDVAGLMKQFFRQLQEPLLTNTYHDSFIKTMRIEDDNTRTKAMLYICLLLPLAHLQALKYTMKFLAEFASHSEKSKMGFSNLAIVLTPNLMHNIRKDNSSS-------------SERLLKDQTV---VIKTLLKNAGSLGMVPDDVFERAKL 251          

Query: 2903 NSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQD-MTDFSKWQPYD-VADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSP 3577
            NS  DLE+ +++        KL    +TS L+  I ++    N    K L +     DT+ S F  S+    GR    +P V+   +++I+  G +  GIFR +G    I ++K+  E  +D +   + W+  + VA +++ YFR L + L  +      I    +   ++    +  VI  LPD    V++ L  FL  +++HS+  +M ++NLAV   P+L   P
Sbjct:  382 NSSDDLEMYYVT--------KLREYIMTSSLKIRIAAE----NQTLVKTLGE---LVDTANS-FQLSIKQITGR---EIPEVVESCVRFIKRFGLDHPGIFRLSGSSTDINDMKQLFECGRDPLAGLNHWKDINAVAGLLRVYFRELEDPLFPSSHYQQFIEASRFPTNEDVIRQVTCVINELPDSVNRVMKYLFKFLKQVSEHSEQNKMDAHNLAVVFGPTLLRIP 589          

Query: 2945 QFLILKKLAMLRLTSLLESHIPSQKSQ--------FNWKFPKLLSQKSKFTD-----TSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLF 3715
            QF++ ++   +++TS LE   PS+K +         NW   K  S     ++     +   +FG  L        +P+P  I   ++++   GP   GIFR++    R  E+K+ ++  +++  F +      A ++K + R LP+C++ ++    L++      +    + I+ ++ NL   +  +L+  L  L  +  ++    MT+YNLAVC++PS+  +P     SSV+                E   A    ++FMI+H   +F
Sbjct:  676 QFILKRRRKAVKITSTLEVQPPSKKWKNPIKKSPIINWAMHKKTSGAKPHSNDIQPVSPGRLFGLPLQDLCTD-EEPVPKPIEELMRHMFRYGPGVTGIFRKSANARRAKEVKQELDSGKEVL-FEEVSVIVTASVLKEFLRRLPDCILDSEYYDDLVATNNIENDAERAQQIKLILENLSVYSIEILKRFLCVLYHIADNADVNNMTAYNLAVCVAPSMLWAP---KGSSVAAT--------------EQSSAVPPVVQFMIEHFVDIF 926          

Query: 3197 GIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKT-----------TQMTSYNLAVCLSPSLFH 3571
            GIFR  G K R+ ++++  +  +     ++  P+DVA + K Y R LPE L+T +L S  +  +         EA+Q +   LP  NR  L +LL FLS +  +++             +M S NLA  + P++ H
Sbjct:    6 GIFRTGGSKKRMKQMREQFDSGEKTQFNAEDNPHDVAALFKEYLRDLPEPLLTRELYSAFLETQGISDTAKEIEALQLLCCLLPAANRDTLNALLAFLSKVDFYAEDKIDDMGCDIPGNKMNSKNLATLIGPNILH 141          

Query: 2864 FRWSSLART---NQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSP--IRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKAR-IQMEFERII-SLSKLLRD--------------CNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLI 4477
             RW S   +   +QP +S   L++S  S  Q  +L+K ++LRLT+++E +  S +  + W  PK + +         SVFG  L     R G PLP  +  A  ++RT   +  G+FR++G K+RI  L++  E + D+ ++     YD+ADM+K +FR LPE L+T+KL  T + I  Y+P++   +A++  I+ +PDENR VLQ LLYFL D+T   +  QMT  NLAVCL PSLFH   ++ + ++SP  I+ + +   PD +DL D  A    L  MI     LF++ EE + ++R   ME E ++  L +L +                  +++ +   ++ L+ E   K K W S                      +  N   + K  E  N +  WR+  E+ A  + +L ++   R  W +++   R+   +    D+ +    S PPQ      ++R  + ++     VLV  SV+               HED         + VL+   ++E    + ++R+  +SRVDLRG S EWY + + H+ +
Sbjct:  515 VRWPSFRTSHHYDQPASS---LQISSQSAGQLSLLQKFSLLRLTAIMEKYSMSNRHGWQWSVPKFMKRMKVPDYKEKSVFGVPLIVHVQRCGFPLPLCLQQAFSHLRTHCLDQVGLFRKSGVKSRIQALRQQCESSPDLVNYDDQSAYDIADMVKQFFRDLPEPLLTSKLGDTFLHIYQYVPKEQRMQAVRAAILLMPDENREVLQMLLYFLRDVTSLVEENQMTPMNLAVCLGPSLFHL-SILKNETLSPRSIQKKYASGRPDQKDLSDNLAATQGLTHMITECQRLFQIPEEMVTQSRNSYMEAELMVPPLDELCKTHEEEAVEEVEDEDEEGSYHAHLEGLIQNLLKEAKDKSKAWVSRS--------------------FSDNTEIASKKVEDGNPLRRWRVCVEVSAAPTEVLQRLLKERSLWQMDLQQERVLETLDRQTDVYHFSCCSMPPQPSCDYVVLRSWRTDLCKGCCVLVCVSVE---------------HEDGPRSAAIRGV-VLESQYLLEPC-GTGRTRLTHISRVDLRGRSPEWYNKAFGHLCV 1032          

Query: 2864 FRWSSLART---NQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSP--IRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKAR-IQMEFERII-SLSKLLRD--------------CNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLI 4477
             RW S   +   +QP +S   L++S  S  Q  +L+K ++LRLT+++E +  S +  + W  PK + +         SVFG  L     R G PLP  +  A  ++RT   +  G+FR++G K+RI  L++  E + D+ ++     YD+ADM+K +FR LPE L+T+KL  T + I  Y+P++   +A++  I+ +PDENR VLQ LLYFL D+T   +  QMT  NLAVCL PSLFH   ++ + ++SP  I+ + +   PD +DL D  A    L  MI     LF++ EE + ++R   ME E ++  L +L +                  +++ +   ++ L+ E   K K W S                      +  N   + K  E  N +  WR+  E+ A  + +L ++   R  W +++   R+   +    D+ +    S PPQ      ++R  + ++     VLV  SV+               HED         + VL+   ++E    + ++R+  +SRVDLRG S EWY + + H+ +
Sbjct:  646 VRWPSFRTSHHYDQPASS---LQISSQSAGQLSLLQKFSLLRLTAIMEKYSMSNRHGWQWSVPKFMKRMKVPDYKEKSVFGVPLIVHVQRCGFPLPLCLQQAFSHLRTHCLDQVGLFRKSGVKSRIQALRQQCESSPDLVNYDDQSAYDIADMVKQFFRDLPEPLLTSKLGDTFLHIYQYVPKEQRMQAVRAAILLMPDENREVLQMLLYFLRDVTSLVEENQMTPMNLAVCLGPSLFHL-SILKNETLSPRSIQKKYASGRPDQKDLSDNLAATQGLTHMITECQRLFQIPEEMVTQSRNSYMEAELMVPPLDELCKTHEEEAVEEVEDEDEEGSYHAHLEGLIQNLLKEAKDKSKAWVSRS--------------------FSDNTEIASKKVEDGNPLRRWRVCVEVSAAPTEVLQRLLKERSLWQMDLQQERVLETLDRQTDVYHFSCCSMPPQPSCDYVVLRSWRTDLCKGCCVLVCVSVE---------------HEDGPRSAAIRGV-VLESQYLLEPC-GTGRTRLTHISRVDLRGRSPEWYNKAFGHLCV 1163          

Query: 2864 FRWSSLART---NQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSP--IRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKAR-IQMEFERII-SLSKLLRD--------------CNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLI 4477
             RW S   +   +QP +S   L++S  S  Q  +L+K ++LRLT+++E +  S +  + W  PK + +         SVFG  L     R G PLP  +  A  ++RT   +  G+FR++G K+RI  L++  E + D+ ++     YD+ADM+K +FR LPE L+T+KL  T + I  Y+P++   +A++  I+ +PDENR VLQ LLYFL D+T   +  QMT  NLAVCL PSLFH   ++ + ++SP  I+ + +   PD +DL D  A    L  MI     LF++ EE + ++R   ME E ++  L +L +                  +++ +   ++ L+ E   K K W S                      +  N   + K  E  N +  WR+  E+ A  + +L ++   R  W +++   R+   +    D+ +    S PPQ      ++R  + ++     VLV  SV+               HED         + VL+   ++E    + ++R+  +SRVDLRG S EWY + + H+ +
Sbjct:  553 VRWPSFRTSHHYDQPASS---LQISSQSAGQLSLLQKFSLLRLTAIMEKYSMSNRHGWQWSVPKFMKRMKVPDYKEKSVFGVPLIVHVQRCGFPLPLCLQQAFSHLRTHCLDQVGLFRKSGVKSRIQALRQQCESSPDLVNYDDQSAYDIADMVKQFFRDLPEPLLTSKLGDTFLHIYQYVPKEQRMQAVRAAILLMPDENREVLQMLLYFLRDVTSLVEENQMTPMNLAVCLGPSLFHL-SILKNETLSPRSIQKKYASGRPDQKDLSDNLAATQGLTHMITECQRLFQIPEEMVTQSRNSYMEAELMVPPLDELCKTHEEEAVEEVEDEDEEGSYHAHLEGLIQNLLKEAKDKSKAWVSRS--------------------FSDNTEIASKKVEDGNPLRRWRVCVEVSAAPTEVLQRLLKERSLWQMDLQQERVLETLDRQTDVYHFSCCSMPPQPSCDYVVLRSWRTDLCKGCCVLVCVSVE---------------HEDGPRSAAIRGV-VLESQYLLEPC-GTGRTRLTHISRVDLRGRSPEWYNKAFGHLCV 1070          

Query: 2864 FRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK--SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKAR-----IQMEFERIISLSKLLRDCNDWY-SWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHV 4471
             RW S   +N+  +S   L++++ S  Q  +L+K ++LRLT+++E +  S K  + W  PK + +         +VFG  L     R GQPLP  +  AL+Y+R+   +  G+FR++G K+RI  L++  E + D  ++     YDVADM+K +FR LPE L+TNKL  T + I  Y+P+    +A+Q  I+ + DENR VLQ+LL FLSD++   +  QMT  N+AVCL+PSLFH  +++   ++SP  M+K  +   PD +DL +  A    L  MI     LF +  E + ++R       +    I  L K L D +  Y + +  +++ L+ E   K K+W S         +D +E+L      YK       K  +G N +  WR++ E++AP S++L+++   R  WD+++   ++   +    ++    + S PP   R+  ++R  + ++      LVS S++               H++         I VL+ + ++E    S KSR+  L R+DL+G + +WY + + H+
Sbjct:  542 LRWPSFQISNRISHSVASLQITNQSAGQLSLLQKFSLLRLTAIMEKYSMSNKHGWTWSVPKFMKRMKVPDYKDKNVFGVPLIVHVQRSGQPLPLGLQQALRYLRSRCLDQVGLFRKSGVKSRIQALRQMNESSADNVNYEDQSAYDVADMVKQFFRDLPEPLLTNKLGETFLHIYQYVPKDQRLQAVQAAIMLMSDENREVLQTLLCFLSDVSSSVEENQMTPTNIAVCLAPSLFHL-NLLKKDNLSPKAMQKKYATGRPDQKDLNENLAATQGLAHMIVECNRLFEIPHEMVTQSRNSYVEADLHAPTIQELCKQLEDDDGTYQTHMEGRLQNLLKEAREKSKSWVSYSS------SDNTELL------YK-------KVGDG-NPLRRWRVSVEVEAPPSVVLNRVLRERHLWDMDLHQWKVCETLDKQTEVFQYVLNSMPPHPSREFVVLRSWRTDLPKGACSLVSVSIE---------------HDECPTIGGVRAI-VLESNYLLEPC-GSGKSRLTHLCRIDLKGRTPDWYNKAFGHL 1047          

Query: 2864 FRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRK--SIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKAR-----IQMEFERIISLSKLLRDCNDWY-SWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHV 4471
             RW S   +N+  +S   L++++ S  Q  +L+K ++LRLT+++E +  S K  + W  PK + +         +VFG  L     R GQPLP  +  AL+Y+R+   +  G+FR++G K+RI  L++  E + D  ++     YDVADM+K +FR LPE L+TNKL  T + I  Y+P+    +A+Q  I+ + DENR VLQ+LL FLSD++   +  QMT  N+AVCL+PSLFH  +++   ++SP  M+K  +   PD +DL +  A    L  MI     LF +  E + ++R       +    I  L K L D +  Y + +  +++ L+ E   K K+W S         +D +E+L      YK       K  +G N +  WR++ E++AP S++L+++   R  WD+++   ++   +    ++    + S PP   R+  ++R  + ++      LVS S++               H++         I VL+ + ++E    S KSR+  L R+DL+G + +WY + + H+
Sbjct:  529 LRWPSFQISNRISHSVASLQITNQSAGQLSLLQKFSLLRLTAIMEKYSMSNKHGWTWSVPKFMKRMKVPDYKDKNVFGVPLIVHVQRSGQPLPLGLQQALRYLRSRCLDQVGLFRKSGVKSRIQALRQMNESSADNVNYEDQSAYDVADMVKQFFRDLPEPLLTNKLGETFLHIYQYVPKDQRLQAVQAAIMLMSDENREVLQTLLCFLSDVSSSVEENQMTPTNIAVCLAPSLFHL-NLLKKDNLSPKAMQKKYATGRPDQKDLNENLAATQGLAHMIVECNRLFEIPHEMVTQSRNSYVEADLHAPTIQELCKQLEDDDGTYQTHMEGRLQNLLKEAREKSKSWVSYSS------SDNTELL------YK-------KVGDG-NPLRRWRVSVEVEAPPSVVLNRVLRERHLWDMDLHQWKVCETLDKQTEVFQYVLNSMPPHPSREFVVLRSWRTDLPKGACSLVSVSIE---------------HDECPTIGGVRAI-VLESNYLLEPC-GSGKSRLTHLCRIDLKGRTPDWYNKAFGHL 1034          

Query: 1283 MNFEAVLFIGNHSETKLPLNLKTSIDWLETKGFHNYVDIYTNANRPINLLEVLKQNNKLNGNDLLTLFGHVEILNQNLTKRHENLNRPQSTMITKTTPNPTSPKFKRDRWSCRLDSSKKPDPFTENKNHQSFLEIEPKINNSLHTFKSSSLRHMSHRNTQLDSVCKNNLHSANEIDFKRKIDSKSLGINVDDMKNLIGCTKHHSLTTVMEQSITDESTNQNQAINENYSQXXXXXXXXXXXXXXXXXAKSVRLKNSSTNIQSVKQPSANLTMKSNLSANIVPEISVASNISETPNLSPRCCSNDSDFLLPTTGNVNLRISNDVPRSTGSNRRYFNSWGYDFELDSGVEELSNDSIDMGEAGRINFRTGSFMTRYRRNSKLSNSQSSPRSVLISPSQHCVNWAWCKDENNQPIIDNVEDELNPVXXXXXXXXXXXXNFRNILHNRRISNNFEEFNSKETCKKELRPKDFIIRKPHLHNKKSNIDKNVQTFEDIENRQQTNSLTRQGSENXXXXXXXXXXXXXXXXNHPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFERIISLSKLLRDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLKVACAQMKI 4522
            MNFEAVLFIGN SETKLPLNLKTSIDWLETKGFHNYVDIYTNANRPINLLEVLKQNNKLNGNDLLTLFGHVEILNQNLT+RHENLNRPQSTMITKT PNPTSPKFKRDRWSCRLDSSKKPDPFTENKNHQSFLEIEPKINNSLHTFKSSSLRHMSHRNTQLDSVCKNNLHSANEIDFKRKIDSKSLGINVDDMKNLIGCTKHHSLTTVMEQSITDESTNQNQAINENYSQLISSISDSNSISSLDSNAKSVRLKNSSTNIQSVKQPSANLTMKSNLSANIVPEISVASNISETPNLSPRCCSNDSDFLLPTTGNVNLRISNDVPRSTGSNRRYFNSWGYDFELDSGVEELSNDSIDMGEAGRINFRTGSFMTRYRRNSKLSNSQSSPRSVLISPSQHCVNWAWCKDE NQPIIDNVEDELNPVLDSLFSDMDSLDNFRNILHNRRISNNF+EFNSK+TCKKELRPKDFIIRKPHLHN+KSNIDKNVQTFEDIENRQQTNSLTRQGSENKFKKSSLKKSASARKRNHPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELK+AIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFERIISLSKLLRDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEY PASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLKVACAQMKI
Sbjct:    1 MNFEAVLFIGNQSETKLPLNLKTSIDWLETKGFHNYVDIYTNANRPINLLEVLKQNNKLNGNDLLTLFGHVEILNQNLTRRHENLNRPQSTMITKTMPNPTSPKFKRDRWSCRLDSSKKPDPFTENKNHQSFLEIEPKINNSLHTFKSSSLRHMSHRNTQLDSVCKNNLHSANEIDFKRKIDSKSLGINVDDMKNLIGCTKHHSLTTVMEQSITDESTNQNQAINENYSQLISSISDSNSISSLDSNAKSVRLKNSSTNIQSVKQPSANLTMKSNLSANIVPEISVASNISETPNLSPRCCSNDSDFLLPTTGNVNLRISNDVPRSTGSNRRYFNSWGYDFELDSGVEELSNDSIDMGEAGRINFRTGSFMTRYRRNSKLSNSQSSPRSVLISPSQHCVNWAWCKDEYNQPIIDNVEDELNPVLDSLFSDMDSLDNFRNILHNRRISNNFDEFNSKDTCKKELRPKDFIIRKPHLHNEKSNIDKNVQTFEDIENRQQTNSLTRQGSENKFKKSSLKKSASARKRNHPFRWSSLARTNQPVNSCRDLELSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTSVFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKRAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINSSSVSPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFERIISLSKLLRDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGFELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQTQRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYLPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLKVACAQMKI 1080          

Query: 2924 LSHLSLNQFLILKKLAMLRLTSLLESHIPSQKSQFNWKFPKLLSQKSKFTDTSTS-VFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQDMTDFSKWQPYDVADMIKSYFRSLPECLMTNKLSSTLISIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVINS-SSVSPIRMRKSIHGPDPRDLEDQKATHHCLKFMIDHAPSLFRLSEETINKARIQMEFERIISLSKLLRDCNDWYSWIRSKVEALINENNHKFKNWTSARKDILKLHNDKSEMLHGF-----ELFYKKNNAQSDKSSEGINSIGTWRITAEIDAPASLILDKIQNSRQEWDLEIAFVRIKREISDSVDICYMEVVSNPPQT--QRQMTLIRGCQRNIDGNINVLVSQSVDDNSPVTDRKPLKQFTHEDHDNDHDYNVINVLQDDVIIEYFPASQKSRINWLSRVDLRGFSSEWYFRQWSHVLIRRLIHLK 4498
            L  LS+ +F +LKK ++L  TS+LE + P QK+ FNW+ P+LL QK K +  +T+ +FG +LS  Q R GQP PPVI +   Y+R  GP + GIFR+ G K RI ELKK +EK +++ +F  +   D+AD++K++FR LP+ L+T+KLSSTL++I  Y+P+++  E ++W + +LPDENR+ L+ L+ FLS L+K+S  T+M + NL++C +PSLF+  +  +S +++SP+RM+KS +GP+ + L +Q A H C+  MI++  SLF+++ E++         +   +    +   N    WIR+K+  L N+ N     WT+  KD +K        LHG      +L Y+K  +  +  ++GI ++ TW++  +I+     +   I++ R  WD ++  + + +EI++ ++ C   +  NP  +   RQ  ++RG Q  ++G+ +++ S+S+ D   +T        +     N  D  + ++  D+ +IE   +++ +R+ W+SRVDL G  S+WY   W H +IRR  HL+
Sbjct:  528 LLELSVTKFNLLKKFSILSCTSMLEKYCP-QKNVFNWRIPRLLPQKQKLSLENTNFIFGVNLSVIQNRFGQPFPPVILNIFSYLRKHGPTTQGIFRKTGMKCRIKELKKEMEKDENLNNFDGYNVNDIADILKTFFRDLPDRLLTHKLSSTLLAIYNYVPKESQCEGLKWALFSLPDENRVALEYLIEFLSYLSKYSDDTKMDAKNLSLCFAPSLFNFQNDGSSNNTMSPLRMKKS-NGPNNKHLAEQNAAHLCVVSMINNTSSLFQITHESLKMGSFNAPDKSDSNDVTHIMSTNLRQEWIRNKMLQLKNDTNANKTGWTNINKDFIK-------KLHGANAVIEQLSYRKIGSNHN-DNDGI-ALRTWKVVIDIEGSPGYLFTYIKDKRHLWDPDMPQMELIKEINEYIE-CVKLISDNPDGSFVPRQFNVLRGHQLGVNGSAHMIFSESMSDEIFLTSNDNFGSVS-----NYSDVLIGHIYCDNFLIEAV-STKLTRVTWISRVDLGGHHSDWYSNHWGHNMIRRAAHLR 1043          

Query: 3089 VFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQD-MTDFSKWQPYDV-ADMIKSYFRSLPECLMTNKLSSTLI-SIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVIN 3589
            +FG +L  +     QP+PP+I++ +  I   G  + GIFR +G +A I ELK+  +  QD   + S+    +V A ++K YFR L E + +  L   ++ + +T   ++++    + ++ ++P E  ++L+ L  FL  +++  +   M SYNLA+C  P L   P+  N
Sbjct:  515 IFGGTLQEYVTLSQQPIPPLIHNTINIINLYGMHNQGIFRISGSQAEINELKEMYDNCQDPFINNSQIPDVNVAAGLLKMYFRELKEPVFSGTLFHQIVETFETEREKKSFINKAREIMNSIPTEIYVILRYLFAFLKYVSELKEDNMMDSYNLAICFGPCLMPIPNEFN 684          

Query: 3089 VFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQD-MTDFSKWQPYDV-ADMIKSYFRSLPECLMTNKLSSTLI-SIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVIN 3589
            +FG +L  +     QP+PP+I++ +  I   G  + GIFR +G +A I ELK+  +  QD   + S+    +V A ++K YFR L E + +  L   ++ + +T   ++++    + ++ ++P E  ++L+ L  FL  +++  +   M SYNLA+C  P L   P+  N
Sbjct:  515 IFGGTLQEYVTLSQQPIPPLIHNTINIINLYGMHNQGIFRISGSQAEINELKEMYDNCQDPFINNSQIPDVNVAAGLLKMYFRELKEPVFSGTLFHQIVETFETEREKKSFINKAREIMNSIPTEIYVILRYLFAFLKYVSELKEDNMMDSYNLAICFGPCLMPIPNEFN 684          

Query: 3089 VFGASLSYWQGRIGQPLPPVIYHALKYIRTVGPESDGIFRRAGGKARITELKKAIEKTQD-MTDFSKWQPYDV-ADMIKSYFRSLPECLMTNKLSSTLI-SIKTYIPEQNWFEAIQWVIINLPDENRLVLQSLLYFLSDLTKHSKTTQMTSYNLAVCLSPSLFHSPHVIN 3589
            +FG +L  +     QP+PP+I++ +  I   G  + GIFR +G +A I ELK+  +  QD   + S+    +V A ++K YFR L E + +  L   ++ + +T   ++++    + ++ ++P E  ++L+ L  FL  +++  +   M SYNLA+C  P L   P+  N
Sbjct:  515 IFGGTLQEYVTLSQQPIPPLIHNTINIINLYGMHNQGIFRISGSQAEINELKEMYDNCQDPFINNSQIPDVNVAAGLLKMYFRELKEPVFSGTLFHQIVETFETEREKKSFINKAREIMNSIPTEIYVILRYLFAFLKYVSELKEDNMMDSYNLAICFGPCLMPIPNEFN 684