Homeobox domain-containing protein

Overview
NameHomeobox domain-containing protein
Smed IDSMED30009987
Length (bp)773
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Homeobox domain-containing protein (SMED30009987) t-SNE clustered cells

Violin plots show distribution of expression levels for Homeobox domain-containing protein (SMED30009987) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Homeobox domain-containing protein (SMED30009987) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Homeobox domain-containing protein (SMED30009987) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30009987

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30009987h1SMcG0000548 SmedASXL_008181SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
parenchymaSMED30009987h1SMcG0000548 dd_Smed_v4_18147_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: EVX1 (even-skipped homeobox 1 [Source:HGNC Symbol;Acc:HGNC:3506])

HSP 1 Score: 107.457 bits (267), Expect = 2.578e-26
Identity = 51/97 (52.58%), Postives = 64/97 (65.98%), Query Frame = 1 
Query:  139 SDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARAYYNFTSQF 429
            SDQM+RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   +  P     +DP  Y+Y++  A A       F
Sbjct:  180 SDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPH---PADPAFYTYMMSHAAAAGGLPYPF 273
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: EVX2 (even-skipped homeobox 2 [Source:HGNC Symbol;Acc:HGNC:3507])

HSP 1 Score: 100.908 bits (250), Expect = 1.035e-23
Identity = 48/88 (54.55%), Postives = 63/88 (71.59%), Query Frame = 1 
Query:  142 DQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARA 405
            DQ++RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   ++ P     +DP  Y+Y++  A A
Sbjct:  186 DQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPH---PADPSFYTYMMTHAAA 270
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: GSX1 (GS homeobox 1 [Source:HGNC Symbol;Acc:HGNC:20374])

HSP 1 Score: 69.707 bits (169), Expect = 2.002e-13
Identity = 33/73 (45.21%), Postives = 47/73 (64.38%), Query Frame = 1 
Query:  115 HSIDFYENSDQM---KRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            H I    +S+Q+   KR RT ++  Q+  LE+EF    YLSRL+R E+A  L L E  +K+WFQNRR+K K++
Sbjct:  133 HCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKE 205
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: HOXB1 (homeobox B1 [Source:HGNC Symbol;Acc:HGNC:5111])

HSP 1 Score: 69.707 bits (169), Expect = 3.111e-13
Identity = 29/55 (52.73%), Postives = 41/55 (74.55%), Query Frame = 1 
Query:  160 RTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            RTN++  Q+  LE+EF   KYLSR +R E+A  L L E+ +K+WFQNRRMK+K++
Sbjct:  207 RTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKR 261
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Match: HOXC4 (homeobox C4 [Source:HGNC Symbol;Acc:HGNC:5126])

HSP 1 Score: 68.9366 bits (167), Expect = 3.209e-13
Identity = 32/62 (51.61%), Postives = 42/62 (67.74%), Query Frame = 1 
Query:  136 NSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKR 321
            N  + KR RT Y+R Q+  LE+EF   +YL+R +R E+A  L L E  IK+WFQNRRMK K+
Sbjct:  152 NGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKK 213
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: vab-7 (Homeobox protein vab-7 [Source:UniProtKB/Swiss-Prot;Acc:Q93899])

HSP 1 Score: 99.3673 bits (246), Expect = 8.331e-25
Identity = 58/108 (53.70%), Postives = 69/108 (63.89%), Query Frame = 1 
Query:  130 YENSD--QMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ----LTTINIPQILANS-DPFLYSYLLDSARAYYNFTSQFG 432
            Y+N D  QM+RYRT +SR QI RLE+EF +E Y+SR  R ELA EL L E TIKVWFQNRRMK+KRQ    L     PQ+ A   +PF Y   + +A A     SQFG
Sbjct:   60 YDNRDDGQMRRYRTAFSREQIGRLEREFAKENYVSRKTRGELAAELNLPEGTIKVWFQNRRMKDKRQRVGGLAWPFPPQMAAYMLNPFAYEMWMKTAAA-----SQFG 162
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: ceh-12 (Homeobox protein ceh-12 [Source:UniProtKB/Swiss-Prot;Acc:P17487])

HSP 1 Score: 73.1738 bits (178), Expect = 1.190e-15
Identity = 33/75 (44.00%), Postives = 52/75 (69.33%), Query Frame = 1 
Query:   97 DEHGDNHSIDFYENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKR 321
            D     +S++ ++   +M+R RT +S  Q+ +LE++F   +YLSR +R +LA++L L E+ IK+WFQNRRMK KR
Sbjct:   93 DHLALTYSVNAWQAWGKMRRPRTAFSSEQLVQLEKQFSDNRYLSRPRRYQLAQQLSLSETQIKIWFQNRRMKNKR 167
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: lin-39 (Homeobox protein lin-39 [Source:UniProtKB/Swiss-Prot;Acc:P34684])

HSP 1 Score: 72.4034 bits (176), Expect = 6.466e-15
Identity = 32/58 (55.17%), Postives = 42/58 (72.41%), Query Frame = 1 
Query:  151 KRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            KR RT Y+RNQ+  LE+EF   KYL+R +R E+A  L L E  +K+WFQNRRMK K++
Sbjct:  166 KRQRTAYTRNQVLELEKEFHTHKYLTRKRRIEVAHSLMLTERQVKIWFQNRRMKHKKE 223
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: lin-39 (Homeobox protein lin-39 [Source:UniProtKB/Swiss-Prot;Acc:P34684])

HSP 1 Score: 72.4034 bits (176), Expect = 6.466e-15
Identity = 32/58 (55.17%), Postives = 42/58 (72.41%), Query Frame = 1 
Query:  151 KRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            KR RT Y+RNQ+  LE+EF   KYL+R +R E+A  L L E  +K+WFQNRRMK K++
Sbjct:  166 KRQRTAYTRNQVLELEKEFHTHKYLTRKRRIEVAHSLMLTERQVKIWFQNRRMKHKKE 223
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Match: ceh-16 (Homeobox protein engrailed-like ceh-16 [Source:UniProtKB/Swiss-Prot;Acc:P34326])

HSP 1 Score: 70.8626 bits (172), Expect = 7.403e-15
Identity = 38/96 (39.58%), Postives = 61/96 (63.54%), Query Frame = 1 
Query:   58 VLSTDEMNKSTSGDEHGDNH---SIDFYENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTI 336
            V ST   ++ ++G  H  +    S     +S++ KR RT ++ +Q++RL+ EFR  +YL+  +R ELA ELGL ES IK+WFQN+R K K+  +++
Sbjct:   54 VFSTRYSDRPSAGPRHRKSRKRESTGSSGSSEEEKRPRTAFTGDQLDRLKTEFRESRYLTEKRRQELAHELGLNESQIKIWFQNKRAKLKKSTSSV 149
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: eve (gene:FBgn0000606 transcript:FBtr0088390)

HSP 1 Score: 98.9821 bits (245), Expect = 9.190e-24
Identity = 44/84 (52.38%), Postives = 60/84 (71.43%), Query Frame = 1 
Query:  148 MKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSA 399
            ++RYRT ++R+Q+ RLE+EF +E Y+SR +R ELA +L L ESTIKVWFQNRRMK+KRQ   +  P     SDP   + +L +A
Sbjct:   70 VRRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIKVWFQNRRMKDKRQRIAVAWPYAAVYSDPAFAASILQAA 153
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: pb (gene:FBgn0051481 transcript:FBtr0089276)

HSP 1 Score: 78.1814 bits (191), Expect = 3.586e-16
Identity = 38/81 (46.91%), Postives = 50/81 (61.73%), Query Frame = 1 
Query:   82 KSTSGDEHGDNHSIDFYENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            KS++ +  GDN   +F   +   +R RT Y+  Q+  LE+EF   KYL R +R E+A  L L E  +KVWFQNRRMK KRQ
Sbjct:  176 KSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQ 256
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: lms (gene:FBgn0034520 transcript:FBtr0342702)

HSP 1 Score: 76.6406 bits (187), Expect = 7.170e-16
Identity = 38/66 (57.58%), Postives = 45/66 (68.18%), Query Frame = 1 
Query:  136 NSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTT 333
              D+ KR RT +S  QI  LE EF R KYLS  KRT LAK+L L E+ IK+WFQNRR K KR+ T+
Sbjct:   82 GDDRKKRPRTAFSAAQIKALETEFERGKYLSVAKRTALAKQLQLTETQIKIWFQNRRTKWKRKYTS 147
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: lms (gene:FBgn0034520 transcript:FBtr0342701)

HSP 1 Score: 76.6406 bits (187), Expect = 7.170e-16
Identity = 38/66 (57.58%), Postives = 45/66 (68.18%), Query Frame = 1 
Query:  136 NSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTT 333
              D+ KR RT +S  QI  LE EF R KYLS  KRT LAK+L L E+ IK+WFQNRR K KR+ T+
Sbjct:   82 GDDRKKRPRTAFSAAQIKALETEFERGKYLSVAKRTALAKQLQLTETQIKIWFQNRRTKWKRKYTS 147
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Match: pb (gene:FBgn0051481 transcript:FBtr0089278)

HSP 1 Score: 73.1738 bits (178), Expect = 2.002e-14
Identity = 37/81 (45.68%), Postives = 48/81 (59.26%), Query Frame = 1 
Query:   82 KSTSGDEHGDNHSIDFYENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            K TS     +N+  +F   +   +R RT Y+  Q+  LE+EF   KYL R +R E+A  L L E  +KVWFQNRRMK KRQ
Sbjct:  171 KKTSRKSSNNNNQAEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQ 251
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: evx1 (even-skipped homeobox 1 [Source:ZFIN;Acc:ZDB-GENE-980526-364])

HSP 1 Score: 104.76 bits (260), Expect = 1.357e-26
Identity = 50/90 (55.56%), Postives = 63/90 (70.00%), Query Frame = 1 
Query:  136 NSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARA 405
             SDQM+RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   +  P     +DP  Y+Y++  A A
Sbjct:   25 GSDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPH---PADPAFYTYMMSHAAA 111
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: evx1 (even-skipped homeobox 1 [Source:ZFIN;Acc:ZDB-GENE-980526-364])

HSP 1 Score: 104.76 bits (260), Expect = 1.357e-26
Identity = 50/90 (55.56%), Postives = 63/90 (70.00%), Query Frame = 1 
Query:  136 NSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARA 405
             SDQM+RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   +  P     +DP  Y+Y++  A A
Sbjct:   25 GSDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPH---PADPAFYTYMMSHAAA 111
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: evx1 (even-skipped homeobox 1 [Source:ZFIN;Acc:ZDB-GENE-980526-364])

HSP 1 Score: 104.375 bits (259), Expect = 1.300e-25
Identity = 50/90 (55.56%), Postives = 63/90 (70.00%), Query Frame = 1 
Query:  136 NSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARA 405
             SDQM+RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   +  P     +DP  Y+Y++  A A
Sbjct:  150 GSDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPH---PADPAFYTYMMSHAAA 236
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: evx2 (even-skipped homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-980526-215])

HSP 1 Score: 100.138 bits (248), Expect = 6.608e-24
Identity = 48/88 (54.55%), Postives = 63/88 (71.59%), Query Frame = 1 
Query:  142 DQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARA 405
            DQ++RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   ++ P     +DP  Y+Y++  A A
Sbjct:  167 DQVRRYRTAFTREQIGRLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPH---PADPSFYTYMMTHAAA 251
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Match: eve1 (even-skipped-like1 [Source:ZFIN;Acc:ZDB-GENE-980526-69])

HSP 1 Score: 93.2041 bits (230), Expect = 1.365e-22
Identity = 50/115 (43.48%), Postives = 71/115 (61.74%), Query Frame = 1 
Query:   61 LSTDEMNKSTSGDEHGDNHSIDFYENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARA 405
            +ST     S  G+E  +   I      DQ +R+RT ++R Q+ RLEQE+ +E Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ  +++ P  L   DP L ++++    A
Sbjct:    9 VSTVAHADSDQGEE--ECPRISLLNGIDQSRRHRTAFTREQLTRLEQEYCKESYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRHSLHWPNPL---DPNLCAFMVGQTAA 118
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: EVX1 (even-skipped homeobox 1 [Source:NCBI gene;Acc:100496893])

HSP 1 Score: 107.457 bits (267), Expect = 4.213e-26
Identity = 73/186 (39.25%), Postives = 93/186 (50.00%), Query Frame = 1 
Query:  139 SDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARAYYNFTSQFGHSPAQPPSKFEAISTETALAAFMSTNKLMPYHGVPNLSHVPAIKPN--CSGECPTIMIPPVSRCYLDQHETQISTFPTQSNACVNIAS 690
             DQM+RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   +  P     +DP  Y+Y++  A A  N    F      P      IS  +  AA   +  L P      LSH P  +P   C+   P+I   P        H    S  P    AC + +S
Sbjct:  268 GDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPH---PADPAFYTYMMSHAAATGNLPYPFPSHLPLPYYSHMGISAGSTTAATPFSAPLRPLDTFRVLSH-PYPRPELLCAFRHPSIYASPA-------HGLGASGSPCTCLACHSTSS 442
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: EVX2 (even-skipped homeobox 2 [Source:NCBI gene;Acc:100498260])

HSP 1 Score: 102.834 bits (255), Expect = 2.101e-24
Identity = 48/89 (53.93%), Postives = 64/89 (71.91%), Query Frame = 1 
Query:  139 SDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARA 405
            +DQ++RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   ++ P     +DP  Y+Y++  A A
Sbjct:  261 ADQVRRYRTAFTREQIGRLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPH---PADPSFYTYMMTHAAA 346
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: rnf20 (ring finger protein 20 [Source:Xenbase;Acc:XB-GENE-5746936])

HSP 1 Score: 70.4774 bits (171), Expect = 7.751e-14
Identity = 39/98 (39.80%), Postives = 56/98 (57.14%), Query Frame = 1 
Query:   64 STDEMNKSTSGDEHGDNHSIDFYEN----------SDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQL 327
            S+DE + + S D+  ++   +  EN          SD  +R RT ++  QI RLEQ F +++YL   +R +LA  L L E  +K WFQNRRMK KRQ+
Sbjct:   89 SSDEFSPAGSEDDGTESSGRNSQENDTEHRSKSPKSDLQRRLRTAFTPQQITRLEQAFNKQRYLGASERKKLATSLQLSEIQVKTWFQNRRMKLKRQI 186
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: VAX1 (ventral anterior homeobox 1 [Source:NCBI gene;Acc:100486982])

HSP 1 Score: 67.3958 bits (163), Expect = 1.691e-13
Identity = 31/60 (51.67%), Postives = 46/60 (76.67%), Query Frame = 1 
Query:  142 DQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKR 321
            D+ KR RT+++  Q+ RLE EF+R +Y+   +RTELA++L L E+ +KVWFQNRR K+K+
Sbjct:   36 DRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKK 95
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Match: dhrs7 (dehydrogenase/reductase (SDR family) member 7 [Source:Xenbase;Acc:XB-GENE-5838792])

HSP 1 Score: 69.707 bits (169), Expect = 2.379e-13
Identity = 30/62 (48.39%), Postives = 43/62 (69.35%), Query Frame = 1 
Query:  139 SDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            S Q    RTN++  Q+  LE+EF   KYL+R +R E+A  L L E+ +K+WFQNRRMK+K++
Sbjct:  207 STQQNTIRTNFTTKQLTELEKEFHFNKYLTRARRVEIAATLELNETQVKIWFQNRRMKQKKR 268
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Evx1 (even-skipped homeobox 1 [Source:MGI Symbol;Acc:MGI:95461])

HSP 1 Score: 107.457 bits (267), Expect = 1.909e-26
Identity = 51/97 (52.58%), Postives = 64/97 (65.98%), Query Frame = 1 
Query:  139 SDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARAYYNFTSQF 429
            SDQM+RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   +  P     +DP  Y+Y++  A A       F
Sbjct:  180 SDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPH---PADPAFYTYMMSHAAAAGGLPYPF 273
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Evx2 (even-skipped homeobox 2 [Source:MGI Symbol;Acc:MGI:95462])

HSP 1 Score: 101.293 bits (251), Expect = 4.774e-24
Identity = 48/88 (54.55%), Postives = 63/88 (71.59%), Query Frame = 1 
Query:  142 DQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARA 405
            DQ++RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   ++ P     +DP  Y+Y++  A A
Sbjct:  189 DQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPH---PADPSFYTYMMTHAAA 273
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Evx2 (even-skipped homeobox 2 [Source:MGI Symbol;Acc:MGI:95462])

HSP 1 Score: 101.293 bits (251), Expect = 4.986e-24
Identity = 48/88 (54.55%), Postives = 63/88 (71.59%), Query Frame = 1 
Query:  142 DQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARA 405
            DQ++RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   ++ P     +DP  Y+Y++  A A
Sbjct:  188 DQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPH---PADPSFYTYMMTHAAA 272
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Gsx1 (GS homeobox 1 [Source:MGI Symbol;Acc:MGI:95842])

HSP 1 Score: 69.707 bits (169), Expect = 1.410e-13
Identity = 33/73 (45.21%), Postives = 47/73 (64.38%), Query Frame = 1 
Query:  115 HSIDFYENSDQM---KRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            H I    +S+Q+   KR RT ++  Q+  LE+EF    YLSRL+R E+A  L L E  +K+WFQNRR+K K++
Sbjct:  132 HCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKE 204
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Match: Hoxb1 (homeobox B1 [Source:MGI Symbol;Acc:MGI:96182])

HSP 1 Score: 69.707 bits (169), Expect = 1.769e-13
Identity = 29/55 (52.73%), Postives = 41/55 (74.55%), Query Frame = 1 
Query:  160 RTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            RTN++  Q+  LE+EF   KYLSR +R E+A  L L E+ +K+WFQNRRMK+K++
Sbjct:  203 RTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKR 257
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|P50476|HOX3_XENLA (Homeobox protein XHOX-3 OS=Xenopus laevis OX=8355 GN=xhox3 PE=2 SV=1)

HSP 1 Score: 107.842 bits (268), Expect = 5.408e-26
Identity = 71/186 (38.17%), Postives = 94/186 (50.54%), Query Frame = 1 
Query:  139 SDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARAYYNFTSQFGHSPAQPPSKFEAISTETALAAFMSTNKLMPYHGVPNLSHVPAIKPN--CSGECPTIMIPPVSRCYLDQHETQISTFPTQSNACVNIAS 690
             DQM+RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   +  P     +DP  Y+Y++  A A  N    F      P      IS  +  AA   +  L P      LSH P  +P+  C+   P+I   P        H       P    AC++ ++
Sbjct:  165 GDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPH---PADPAFYTYMMSHAAATGNLPYPFPSHLPLPYYSHMGISAGSTAAATPFSAPLRPLDTFRVLSH-PYPRPDLLCAFRHPSIYASPA-------HGLGSGGSPCSCLACLSTST 339
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|P49640|EVX1_HUMAN (Homeobox even-skipped homolog protein 1 OS=Homo sapiens OX=9606 GN=EVX1 PE=2 SV=1)

HSP 1 Score: 107.457 bits (267), Expect = 1.238e-25
Identity = 51/97 (52.58%), Postives = 64/97 (65.98%), Query Frame = 1 
Query:  139 SDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARAYYNFTSQF 429
            SDQM+RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   +  P     +DP  Y+Y++  A A       F
Sbjct:  180 SDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPH---PADPAFYTYMMSHAAAAGGLPYPF 273
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|P23683|EVX1_MOUSE (Homeobox even-skipped homolog protein 1 OS=Mus musculus OX=10090 GN=Evx1 PE=2 SV=1)

HSP 1 Score: 107.457 bits (267), Expect = 1.335e-25
Identity = 51/97 (52.58%), Postives = 64/97 (65.98%), Query Frame = 1 
Query:  139 SDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARAYYNFTSQF 429
            SDQM+RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   +  P     +DP  Y+Y++  A A       F
Sbjct:  180 SDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPH---PADPAFYTYMMSHAAAAGGLPYPF 273
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|Q93899|VAB7_CAEEL (Homeobox protein vab-7 OS=Caenorhabditis elegans OX=6239 GN=vab-7 PE=1 SV=2)

HSP 1 Score: 99.3673 bits (246), Expect = 1.060e-23
Identity = 58/108 (53.70%), Postives = 69/108 (63.89%), Query Frame = 1 
Query:  130 YENSD--QMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ----LTTINIPQILANS-DPFLYSYLLDSARAYYNFTSQFG 432
            Y+N D  QM+RYRT +SR QI RLE+EF +E Y+SR  R ELA EL L E TIKVWFQNRRMK+KRQ    L     PQ+ A   +PF Y   + +A A     SQFG
Sbjct:   60 YDNRDDGQMRRYRTAFSREQIGRLEREFAKENYVSRKTRGELAAELNLPEGTIKVWFQNRRMKDKRQRVGGLAWPFPPQMAAYMLNPFAYEMWMKTAAA-----SQFG 162
[Close]
BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9IA18|EVX2_HETFR (Homeobox even-skipped homolog protein 2 OS=Heterodontus francisci OX=7792 GN=EVX2 PE=3 SV=1)

HSP 1 Score: 100.908 bits (250), Expect = 3.036e-23
Identity = 48/88 (54.55%), Postives = 63/88 (71.59%), Query Frame = 1 
Query:  142 DQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARA 405
            DQ++RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   ++ P     +DP  Y+Y++  A A
Sbjct:  177 DQVRRYRTAFTREQIGRLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPH---PADPSFYTYMMTHAAA 261
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: A0A1I8HSD3 (Homeobox domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 116.316 bits (290), Expect = 1.073e-27
Identity = 60/136 (44.12%), Postives = 85/136 (62.50%), Query Frame = 1 
Query:  103 HGDNHSIDFYENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARAYYNFTSQFGHSPAQPPSKFEAISTETALAAFMSTN 510
            H  +  +    +   +KRYRT +SR Q++RLE+E+RRE Y+SR +R ELA +LGL ESTIKVWFQNRRMK+KRQ    + P  LA ++P LY+YL+ +A + Y++    G +P Q PS      T   +   +  N
Sbjct:   74 HQSSGGLGGAADDPNLKRYRTAFSREQLDRLEKEYRRESYVSRPRRCELATQLGLPESTIKVWFQNRRMKDKRQRIAQSWPYNLAVANPQLYTYLVRAA-SVYHYCVSIGANPPQIPSPTLTQPTSIGVGGDVEAN 208
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: A0A423SC65 (Transcription factor OS=Penaeus vannamei OX=6689 GN=C7M84_020401 PE=4 SV=1)

HSP 1 Score: 117.857 bits (294), Expect = 1.884e-27
Identity = 73/178 (41.01%), Postives = 98/178 (55.06%), Query Frame = 1 
Query:   64 STDEMNKSTSGDEHGDNHSIDFYENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARAYYNFTSQFGHSPAQPPSKF-EAISTETALAAFMST-NKLMPYHGVPNLSHVPAIKPNCSGECPT 591
            ST   + S          S    +N+ +++RYRT ++R QI RLE+EF RE Y+SR +R ELA+ELGL E+TIKVWFQNRRMK+KRQ   ++ P     +DP L +YLL +A A         + P  PP+    A  T T ++A     + L P    P L H PA    C+G  PT
Sbjct:   61 STKPSDASAEDKSSATPKSTPTGQNAAELRRYRTAFTREQIGRLEKEFLRENYVSRPRRCELAQELGLSEATIKVWFQNRRMKDKRQRMAVSWP----YADPALTAYLLHAAAA------SGAYPPYLPPASMPSAPWTPTGVSAGRRPHHPLSPTLPAPMLPH-PAAAAMCAGHLPT 227
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: A0A1I8HK93 (Homeobox domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 116.701 bits (291), Expect = 2.675e-27
Identity = 60/136 (44.12%), Postives = 85/136 (62.50%), Query Frame = 1 
Query:  103 HGDNHSIDFYENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARAYYNFTSQFGHSPAQPPSKFEAISTETALAAFMSTN 510
            H  +  +    +   +KRYRT +SR Q++RLE+E+RRE Y+SR +R ELA +LGL ESTIKVWFQNRRMK+KRQ    + P  LA ++P LY+YL+ +A + Y++    G +P Q PS      T   +   +  N
Sbjct:   74 HQSSGGLGGAADDPNLKRYRTAFSREQLDRLEKEYRRESYVSRPRRCELATQLGLPESTIKVWFQNRRMKDKRQRIAQSWPYNLAVANPQLYTYLVRAA-SVYHYCVSIGANPPQIPSPTLTQPTSIGVGGDVEAN 208
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: A0A267GRN6 (Homeobox domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig024179g1 PE=4 SV=1)

HSP 1 Score: 116.701 bits (291), Expect = 3.505e-27
Identity = 60/136 (44.12%), Postives = 85/136 (62.50%), Query Frame = 1 
Query:  103 HGDNHSIDFYENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARAYYNFTSQFGHSPAQPPSKFEAISTETALAAFMSTN 510
            H  +  +    +   +KRYRT +SR Q++RLE+E+RRE Y+SR +R ELA +LGL ESTIKVWFQNRRMK+KRQ    + P  LA ++P LY+YL+ +A + Y++    G +P Q PS      T   +   +  N
Sbjct:   74 HQSSGGLGGAADDPNLKRYRTAFSREQLDRLEKEYRRESYVSRPRRCELATQLGLPESTIKVWFQNRRMKDKRQRIAQSWPYNLAVANPQLYTYLVRAA-SVYHYCVSIGANPPQIPSPTLTQPTSIGVGGDVEAN 208
[Close]
BLAST of Homeobox domain-containing protein vs. TrEMBL
Match: A0A267FXH7 (Homeobox domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig024179g3 PE=4 SV=1)

HSP 1 Score: 116.701 bits (291), Expect = 3.801e-27
Identity = 60/136 (44.12%), Postives = 85/136 (62.50%), Query Frame = 1 
Query:  103 HGDNHSIDFYENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARAYYNFTSQFGHSPAQPPSKFEAISTETALAAFMSTN 510
            H  +  +    +   +KRYRT +SR Q++RLE+E+RRE Y+SR +R ELA +LGL ESTIKVWFQNRRMK+KRQ    + P  LA ++P LY+YL+ +A + Y++    G +P Q PS      T   +   +  N
Sbjct:   74 HQSSGGLGGAADDPNLKRYRTAFSREQLDRLEKEYRRESYVSRPRRCELATQLGLPESTIKVWFQNRRMKDKRQRIAQSWPYNLAVANPQLYTYLVRAA-SVYHYCVSIGANPPQIPSPTLTQPTSIGVGGDVEAN 208
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: evx1 (homeobox protein XHOX-3 [Source:NCBI gene;Acc:103047662])

HSP 1 Score: 103.99 bits (258), Expect = 2.296e-25
Identity = 50/90 (55.56%), Postives = 62/90 (68.89%), Query Frame = 1 
Query:  136 NSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARA 405
              DQM+RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   +  P     +DP  Y+Y+L  A A
Sbjct:  174 GPDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPH---PADPAFYTYMLSHAAA 260
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: evx2 (even-skipped homeobox 2 [Source:NCBI gene;Acc:103032927])

HSP 1 Score: 101.679 bits (252), Expect = 1.549e-24
Identity = 48/88 (54.55%), Postives = 63/88 (71.59%), Query Frame = 1 
Query:  142 DQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARA 405
            DQ++RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   ++ P     +DP  Y+Y++  A A
Sbjct:  170 DQVRRYRTAFTREQIGRLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPH---PADPSFYTYMMTHAAA 254
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: eve1 (homeobox even-skipped homolog protein 1-like [Source:NCBI gene;Acc:103043644])

HSP 1 Score: 91.6633 bits (226), Expect = 6.739e-22
Identity = 43/95 (45.26%), Postives = 64/95 (67.37%), Query Frame = 1 
Query:  121 IDFYENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARA 405
            +      +  +R+RT ++R Q++RLEQE+ +E Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ  +++ P  L   DP L ++++  A A
Sbjct:   29 MALLAGVEHSRRHRTAFTREQLSRLEQEYGKESYVSRARRCELAAALNLPETTIKVWFQNRRMKDKRQRHSLSWPHPL---DPNLCAFMVSQAAA 120
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: eve1 (homeobox even-skipped homolog protein 1-like [Source:NCBI gene;Acc:103043644])

HSP 1 Score: 91.6633 bits (226), Expect = 8.246e-22
Identity = 43/95 (45.26%), Postives = 64/95 (67.37%), Query Frame = 1 
Query:  121 IDFYENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARA 405
            +      +  +R+RT ++R Q++RLEQE+ +E Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ  +++ P  L   DP L ++++  A A
Sbjct:   32 MALLAGVEHSRRHRTAFTREQLSRLEQEYGKESYVSRARRCELAAALNLPETTIKVWFQNRRMKDKRQRHSLSWPHPL---DPNLCAFMVSQAAA 123
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000045941.1 (pancreas/duodenum homeobox protein 1-like [Source:NCBI gene;Acc:103022002])

HSP 1 Score: 72.0182 bits (175), Expect = 7.584e-15
Identity = 36/66 (54.55%), Postives = 47/66 (71.21%), Query Frame = 1 
Query:  127 FYENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            F E+S++ KR RT YSR Q+  LE+EF   +Y+SR +R ELA  L L E  IK+WFQNRRMK K++
Sbjct:  128 FCEDSEEHKRSRTAYSRAQLLELEKEFLFNRYISRPRRYELATSLNLTERHIKIWFQNRRMKWKKE 193
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007048.1 (pep scaffold:Pmarinus_7.0:GL477014:324574:325823:1 gene:ENSPMAG00000006377.1 transcript:ENSPMAT00000007048.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 68.1662 bits (165), Expect = 4.165e-15
Identity = 31/60 (51.67%), Postives = 44/60 (73.33%), Query Frame = 1 
Query:  136 NSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKE 315
             SD ++RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIK+W   R++++
Sbjct:   27 GSDGVRRYRTAFTREQIGRLEKEFYRENYVSRPRRCELAAALNLPETTIKIWKDERQIQQ 86
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007188.1 (pep scaffold:Pmarinus_7.0:GL477571:301368:307708:1 gene:ENSPMAG00000006495.1 transcript:ENSPMAT00000007188.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 70.4774 bits (171), Expect = 2.671e-14
Identity = 29/55 (52.73%), Postives = 41/55 (74.55%), Query Frame = 1 
Query:  160 RTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            RTN+S  Q+  LE+EF   KYL+R +R E+A  L L E+ +K+WFQNRRMK+K++
Sbjct:  301 RTNFSTKQLTELEKEFHFNKYLTRARRVEIAAALQLNETQVKIWFQNRRMKQKKR 355
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000986.1 (pep scaffold:Pmarinus_7.0:GL477479:36520:39429:-1 gene:ENSPMAG00000000894.1 transcript:ENSPMAT00000000986.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 62.3882 bits (150), Expect = 5.696e-13
Identity = 30/60 (50.00%), Postives = 41/60 (68.33%), Query Frame = 1 
Query:  151 KRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLT 330
            KR RT +S  Q+  LE+EF   +YLSRL+R  +A  L L E  +K+WFQNRR+K+K+  T
Sbjct:    3 KRARTAFSSGQLLALEREFSASRYLSRLRRIHVAARLRLSEKQVKIWFQNRRVKQKKSET 62
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: hoxd4a (homeobox D4a [Source:NCBI gene;Acc:30329])

HSP 1 Score: 61.2326 bits (147), Expect = 9.356e-13
Identity = 31/57 (54.39%), Postives = 40/57 (70.18%), Query Frame = 1 
Query:  151 KRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKR 321
            KR RT Y+R Q+  LE+EF   +YL+R +R E+A  L L E  IK+WFQNRRMK K+
Sbjct:    3 KRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKK 59
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011116.1 (pep scaffold:Pmarinus_7.0:GL482944:7995:8174:-1 gene:ENSPMAG00000010089.1 transcript:ENSPMAT00000011116.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 59.3066 bits (142), Expect = 2.643e-12
Identity = 28/58 (48.28%), Postives = 41/58 (70.69%), Query Frame = 1 
Query:  151 KRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            ++ R +YSR+Q   LE+EF   +YL+R +R E+A  L L E  +K+WFQNRRMK K++
Sbjct:    2 RKGRRSYSRHQSLELEKEFHFNRYLARRRRVEIAHSLCLSERQVKIWFQNRRMKWKKE 59
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Yeast
Match: YOX1 (Homeobox transcriptional repressor; binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; phosphorylated by Cdc28p; relocalizes from nucleus to cytoplasm upon DNA replication stress; YOX1 has a paralog, YHP1, that arose from the whole genome duplication [Source:SGD;Acc:S000004489])

HSP 1 Score: 45.4394 bits (106), Expect = 3.763e-6
Identity = 22/64 (34.38%), Postives = 37/64 (57.81%), Query Frame = 1 
Query:  133 ENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            +N+   +R R   S  +++ L+ EF +    S+ KR ELA+   + E  +++WFQN+R   KRQ
Sbjct:  171 DNAPLARRKRRRTSSQELSILQAEFEKCPAPSKEKRIELAESCHMTEKAVQIWFQNKRQAVKRQ 234
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: EDO45606 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSC0])

HSP 1 Score: 66.2402 bits (160), Expect = 1.305e-14
Identity = 32/58 (55.17%), Postives = 43/58 (74.14%), Query Frame = 1 
Query:  151 KRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            KR RT+++  Q++RLE EFR + Y+  LKR +LA +L L E  +KVWFQNRRMK KR+
Sbjct:    1 KRSRTSFTPAQLDRLEDEFRVDMYVVGLKRMKLANDLNLSERQVKVWFQNRRMKYKRE 58
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: EDO37100 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGN8])

HSP 1 Score: 65.855 bits (159), Expect = 1.818e-14
Identity = 32/58 (55.17%), Postives = 43/58 (74.14%), Query Frame = 1 
Query:  151 KRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            KR RT+++  Q++RLE EFR + Y+  LKR +LA +L L E  +KVWFQNRRMK KR+
Sbjct:    1 KRSRTSFTPAQLDRLEDEFRVDMYVVGLKRMKLANDLNLSERQVKVWFQNRRMKYKRE 58
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: EDO46621 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPR9])

HSP 1 Score: 70.4774 bits (171), Expect = 6.839e-14
Identity = 31/61 (50.82%), Postives = 42/61 (68.85%), Query Frame = 1 
Query:  151 KRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTT 333
            KR RT ++  QI  LE EF++ KYL+  +R ELA  L L ++ IK+WFQNRR K KR+L +
Sbjct: 1044 KRTRTAFTNTQIRELEAEFQKNKYLTITRRAELANSLELSDTQIKIWFQNRRTKLKRKLAS 1104
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: ANTH.HBXA.NV (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFC2])

HSP 1 Score: 63.929 bits (154), Expect = 8.398e-14
Identity = 29/48 (60.42%), Postives = 38/48 (79.17%), Query Frame = 1 
Query:  169 YSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMK 312
            +S NQI RLE+EF+ EKYL+  KR EL+K+LG+ E+ +K WFQNRR K
Sbjct:   13 FSHNQIQRLEKEFKEEKYLTESKRAELSKDLGMTETQVKTWFQNRRTK 60
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BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Match: MOXB (MoxB; Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR28])

HSP 1 Score: 64.6994 bits (156), Expect = 1.245e-13
Identity = 32/63 (50.79%), Postives = 45/63 (71.43%), Query Frame = 1 
Query:  133 ENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKR 321
            +N  + ++ RT ++++QI  LE EF+R  YL+RL+R E+A  L L E  +KVWFQNRRMK KR
Sbjct:   11 KNLGKKRKERTAFTKHQIQELENEFQRNNYLTRLRRYEIAVSLDLTERQVKVWFQNRRMKWKR 73
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BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: evx2 (even-skipped homeobox 2 [Source:NCBI gene;Acc:101162561])

HSP 1 Score: 105.916 bits (263), Expect = 4.325e-26
Identity = 55/110 (50.00%), Postives = 71/110 (64.55%), Query Frame = 1 
Query:   76 MNKSTSGDEHGDNHSIDFYENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARA 405
            MN ST G  +          NSDQ++RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   ++ P     +DP  Y+Y++  A A
Sbjct:  151 MNGSTGGSNN---------SNSDQVRRYRTAFTREQIGRLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPH---PADPSFYTYMMTHAAA 248
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BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: evx1 (even-skipped homeobox 1 [Source:NCBI gene;Acc:101162614])

HSP 1 Score: 102.834 bits (255), Expect = 3.568e-25
Identity = 50/97 (51.55%), Postives = 65/97 (67.01%), Query Frame = 1 
Query:  139 SDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARAYYNFTSQF 429
            +DQ++RYRT ++R QI RLE+EF RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ   +  P     +DP  Y+Y++  A A  N    F
Sbjct:  152 ADQIRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPH---PADPAFYTYMMSHAAATGNLPYAF 245
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BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: eve1 (homeobox protein XHOX-3 [Source:NCBI gene;Acc:101169040])

HSP 1 Score: 89.7373 bits (221), Expect = 3.065e-21
Identity = 47/96 (48.96%), Postives = 64/96 (66.67%), Query Frame = 1 
Query:  142 DQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARAYYNFTSQF 429
            DQ +R+RT+++R Q++RLEQE+ RE Y+SR +R ELA  L L E+TIKVWFQNRRMK+KRQ  ++  P      DP L + L+  A +    T  F
Sbjct:   34 DQNRRHRTSFTREQLSRLEQEYGRESYVSRPRRCELATALNLPETTIKVWFQNRRMKDKRQRHSLPWPHPFI--DP-LGALLMSRASSSSTLTYPF 126
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: hoxa1a (homeobox protein Hox-A1a [Source:NCBI gene;Acc:101160743])

HSP 1 Score: 73.9442 bits (180), Expect = 5.041e-15
Identity = 34/79 (43.04%), Postives = 50/79 (63.29%), Query Frame = 1 
Query:  130 YENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSD 366
            Y  S Q    RTN++  Q+  LE+EF   KYL+R +R E+A  L L E+ +K+WFQNRRMK+K++     +P  ++ SD
Sbjct:  207 YGYSGQPNTVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAAALQLNETQVKIWFQNRRMKQKKREKEGLMPAKVSTSD 285
[Close]
BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Match: hoxa2b (homeobox protein Hox-A2b [Source:NCBI gene;Acc:101159040])

HSP 1 Score: 72.0182 bits (175), Expect = 2.782e-14
Identity = 34/58 (58.62%), Postives = 40/58 (68.97%), Query Frame = 1 
Query:  151 KRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            KR RT Y+ NQ+  LE+EF   KYL R +R E+A  L L E  +KVWFQNRRMK KRQ
Sbjct:  116 KRLRTAYTNNQLLELEKEFHFNKYLCRPRRVEIAALLDLSEKQVKVWFQNRRMKHKRQ 173
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BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000015136.1 (SMESG000015136.1)

HSP 1 Score: 461.07 bits (1185), Expect = 3.109e-167
Identity = 219/219 (100.00%), Postives = 219/219 (100.00%), Query Frame = 1 
Query:   76 MNKSTSGDEHGDNHSIDFYENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARAYYNFTSQFGHSPAQPPSKFEAISTETALAAFMSTNKLMPYHGVPNLSHVPAIKPNCSGECPTIMIPPVSRCYLDQHETQISTFPTQSNACVNIASIKKSEITFRPYMDS 732
            MNKSTSGDEHGDNHSIDFYENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARAYYNFTSQFGHSPAQPPSKFEAISTETALAAFMSTNKLMPYHGVPNLSHVPAIKPNCSGECPTIMIPPVSRCYLDQHETQISTFPTQSNACVNIASIKKSEITFRPYMDS
Sbjct:    1 MNKSTSGDEHGDNHSIDFYENSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFLYSYLLDSARAYYNFTSQFGHSPAQPPSKFEAISTETALAAFMSTNKLMPYHGVPNLSHVPAIKPNCSGECPTIMIPPVSRCYLDQHETQISTFPTQSNACVNIASIKKSEITFRPYMDS 219
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000080661.1 (SMESG000080661.1)

HSP 1 Score: 70.0922 bits (170), Expect = 1.407e-13
Identity = 28/55 (50.91%), Postives = 42/55 (76.36%), Query Frame = 1 
Query:  160 RTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            RTN++  Q+  LE+EF   +YL+R +R E+A  +GL E+ +K+WFQNRRMK+KR+
Sbjct:  308 RTNFTNKQLTELEKEFHFNQYLTRARRIEIANSMGLSETQVKIWFQNRRMKQKRR 362
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000071019.1 (SMESG000071019.1)

HSP 1 Score: 69.3218 bits (168), Expect = 2.268e-13
Identity = 35/67 (52.24%), Postives = 45/67 (67.16%), Query Frame = 1 
Query:  136 NSDQM-----KRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKR 321
            N DQ+     KR RT Y+R QI  LE+EF   KYL+R +R E+A+ L L E  +K+WFQNRRMK K+
Sbjct:  216 NVDQLILSDSKRNRTAYTRQQILELEKEFHFNKYLTRKRRIEIAQSLQLSERQVKIWFQNRRMKWKK 282
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000062714.1 (SMESG000062714.1)

HSP 1 Score: 68.5514 bits (166), Expect = 2.898e-13
Identity = 33/59 (55.93%), Postives = 41/59 (69.49%), Query Frame = 1 
Query:  145 QMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKR 321
            + ++ RT +S+ QI  LE+EF    YL+RL+R ELA  L L E  IKVWFQNRRMK KR
Sbjct:  230 KQRKERTAFSKGQILELEKEFSVHNYLTRLRRYELAVALNLNERQIKVWFQNRRMKCKR 288
[Close]
BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Match: SMESG000022667.1 (SMESG000022667.1)

HSP 1 Score: 67.3958 bits (163), Expect = 4.914e-13
Identity = 33/63 (52.38%), Postives = 42/63 (66.67%), Query Frame = 1 
Query:  136 NSDQMKRYRTNYSRNQINRLEQEFRREKYLSRLKRTELAKELGLKESTIKVWFQNRRMKEKRQ 324
            NS   KR R  Y+R+Q   LE+EF   KYL+R +R E+A  L L E  IK+WFQNRRMK K++
Sbjct:  159 NSSNNKRTRQTYTRHQTLELEKEFHFNKYLTRRRRIEIAHSLILTERQIKIWFQNRRMKWKKE 221
The following BLAST results are available for this feature:
BLAST of Homeobox domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
EVX12.578e-2652.58even-skipped homeobox 1 [Source:HGNC Symbol;Acc:HG... [more]
EVX21.035e-2354.55even-skipped homeobox 2 [Source:HGNC Symbol;Acc:HG... [more]
GSX12.002e-1345.21GS homeobox 1 [Source:HGNC Symbol;Acc:HGNC:20374][more]
HOXB13.111e-1352.73homeobox B1 [Source:HGNC Symbol;Acc:HGNC:5111][more]
HOXC43.209e-1351.61homeobox C4 [Source:HGNC Symbol;Acc:HGNC:5126][more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
vab-78.331e-2553.70Homeobox protein vab-7 [Source:UniProtKB/Swiss-Pr... [more]
ceh-121.190e-1544.00Homeobox protein ceh-12 [Source:UniProtKB/Swiss-P... [more]
lin-396.466e-1555.17Homeobox protein lin-39 [Source:UniProtKB/Swiss-P... [more]
lin-396.466e-1555.17Homeobox protein lin-39 [Source:UniProtKB/Swiss-P... [more]
ceh-167.403e-1539.58Homeobox protein engrailed-like ceh-16 [Source:Un... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
eve9.190e-2452.38gene:FBgn0000606 transcript:FBtr0088390[more]
pb3.586e-1646.91gene:FBgn0051481 transcript:FBtr0089276[more]
lms7.170e-1657.58gene:FBgn0034520 transcript:FBtr0342702[more]
lms7.170e-1657.58gene:FBgn0034520 transcript:FBtr0342701[more]
pb2.002e-1445.68gene:FBgn0051481 transcript:FBtr0089278[more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
evx11.357e-2655.56even-skipped homeobox 1 [Source:ZFIN;Acc:ZDB-GENE-... [more]
evx11.357e-2655.56even-skipped homeobox 1 [Source:ZFIN;Acc:ZDB-GENE-... [more]
evx11.300e-2555.56even-skipped homeobox 1 [Source:ZFIN;Acc:ZDB-GENE-... [more]
evx26.608e-2454.55even-skipped homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-... [more]
eve11.365e-2243.48even-skipped-like1 [Source:ZFIN;Acc:ZDB-GENE-98052... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
EVX14.213e-2639.25even-skipped homeobox 1 [Source:NCBI gene;Acc:1004... [more]
EVX22.101e-2453.93even-skipped homeobox 2 [Source:NCBI gene;Acc:1004... [more]
rnf207.751e-1439.80ring finger protein 20 [Source:Xenbase;Acc:XB-GENE... [more]
VAX11.691e-1351.67ventral anterior homeobox 1 [Source:NCBI gene;Acc:... [more]
dhrs72.379e-1348.39dehydrogenase/reductase (SDR family) member 7 [Sou... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Evx11.909e-2652.58even-skipped homeobox 1 [Source:MGI Symbol;Acc:MGI... [more]
Evx24.774e-2454.55even-skipped homeobox 2 [Source:MGI Symbol;Acc:MGI... [more]
Evx24.986e-2454.55even-skipped homeobox 2 [Source:MGI Symbol;Acc:MGI... [more]
Gsx11.410e-1345.21GS homeobox 1 [Source:MGI Symbol;Acc:MGI:95842][more]
Hoxb11.769e-1352.73homeobox B1 [Source:MGI Symbol;Acc:MGI:96182][more]
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BLAST of Homeobox domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P50476|HOX3_XENLA5.408e-2638.17Homeobox protein XHOX-3 OS=Xenopus laevis OX=8355 ... [more]
sp|P49640|EVX1_HUMAN1.238e-2552.58Homeobox even-skipped homolog protein 1 OS=Homo sa... [more]
sp|P23683|EVX1_MOUSE1.335e-2552.58Homeobox even-skipped homolog protein 1 OS=Mus mus... [more]
sp|Q93899|VAB7_CAEEL1.060e-2353.70Homeobox protein vab-7 OS=Caenorhabditis elegans O... [more]
sp|Q9IA18|EVX2_HETFR3.036e-2354.55Homeobox even-skipped homolog protein 2 OS=Heterod... [more]
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BLAST of Homeobox domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8HSD31.073e-2744.12Homeobox domain-containing protein OS=Macrostomum ... [more]
A0A423SC651.884e-2741.01Transcription factor OS=Penaeus vannamei OX=6689 G... [more]
A0A1I8HK932.675e-2744.12Homeobox domain-containing protein OS=Macrostomum ... [more]
A0A267GRN63.505e-2744.12Homeobox domain-containing protein OS=Macrostomum ... [more]
A0A267FXH73.801e-2744.12Homeobox domain-containing protein OS=Macrostomum ... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
evx12.296e-2555.56homeobox protein XHOX-3 [Source:NCBI gene;Acc:1030... [more]
evx21.549e-2454.55even-skipped homeobox 2 [Source:NCBI gene;Acc:1030... [more]
eve16.739e-2245.26homeobox even-skipped homolog protein 1-like [Sour... [more]
eve18.246e-2245.26homeobox even-skipped homolog protein 1-like [Sour... [more]
ENSAMXT00000045941.17.584e-1554.55pancreas/duodenum homeobox protein 1-like [Source:... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000007048.14.165e-1551.67pep scaffold:Pmarinus_7.0:GL477014:324574:325823:1... [more]
ENSPMAT00000007188.12.671e-1452.73pep scaffold:Pmarinus_7.0:GL477571:301368:307708:1... [more]
ENSPMAT00000000986.15.696e-1350.00pep scaffold:Pmarinus_7.0:GL477479:36520:39429:-1 ... [more]
hoxd4a9.356e-1354.39homeobox D4a [Source:NCBI gene;Acc:30329][more]
ENSPMAT00000011116.12.643e-1248.28pep scaffold:Pmarinus_7.0:GL482944:7995:8174:-1 ge... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
YOX13.763e-634.38Homeobox transcriptional repressor; binds to Mcm1p... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO456061.305e-1455.17Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO371001.818e-1455.17Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO466216.839e-1450.82Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
ANTH.HBXA.NV8.398e-1460.42Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
MOXB1.245e-1350.79MoxB; Predicted protein [Source:UniProtKB/TrEMBL;... [more]
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BLAST of Homeobox domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
evx24.325e-2650.00even-skipped homeobox 2 [Source:NCBI gene;Acc:1011... [more]
evx13.568e-2551.55even-skipped homeobox 1 [Source:NCBI gene;Acc:1011... [more]
eve13.065e-2148.96homeobox protein XHOX-3 [Source:NCBI gene;Acc:1011... [more]
hoxa1a5.041e-1543.04homeobox protein Hox-A1a [Source:NCBI gene;Acc:101... [more]
hoxa2b2.782e-1458.62homeobox protein Hox-A2b [Source:NCBI gene;Acc:101... [more]
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BLAST of Homeobox domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000015136.13.109e-167100.00SMESG000015136.1[more]
SMESG000080661.11.407e-1350.91SMESG000080661.1[more]
SMESG000071019.12.268e-1352.24SMESG000071019.1[more]
SMESG000062714.12.898e-1355.93SMESG000062714.1[more]
SMESG000022667.14.914e-1352.38SMESG000022667.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30009987 ID=SMED30009987|Name=Homeobox domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=773bp
TGCAGATGAATTCAAATCATTTGAGTAAGTTACCATTCTTTATAATTTTT
CATCAATGTTCTTTCAACAGACGAAATGAATAAATCGACATCAGGTGACG
AACACGGGGATAATCATTCAATTGATTTCTATGAGAATAGTGATCAAATG
AAACGCTATAGAACAAATTATTCAAGAAATCAAATTAACAGATTAGAACA
AGAATTCAGAAGGGAAAAATATTTATCAAGATTAAAAAGAACGGAATTGG
CCAAAGAGTTAGGGTTAAAGGAATCGACAATAAAAGTGTGGTTTCAGAAT
CGTCGAATGAAGGAAAAACGCCAACTGACGACAATAAACATACCGCAGAT
ATTGGCAAATTCAGATCCATTTCTTTATTCCTATTTGTTGGATAGTGCTA
GAGCTTACTACAATTTCACCTCCCAATTCGGTCATTCACCTGCCCAACCG
CCATCGAAATTCGAAGCCATTTCCACCGAAACAGCTTTAGCCGCTTTTAT
GAGTACGAACAAATTAATGCCATATCATGGTGTTCCAAATTTGTCACACG
TTCCAGCCATAAAACCCAATTGTTCAGGAGAATGCCCTACAATCATGATT
CCGCCAGTATCTCGCTGTTATTTAGACCAACACGAAACTCAGATTTCAAC
TTTCCCTACCCAGTCGAATGCCTGCGTTAATATTGCGTCGATAAAGAAAT
CAGAAATCACATTCAGACCGTACATGGATTCCTAAGTTTATCAACTTTCC
AATTGTAAATAAATAAATCTGGC
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protein sequence of SMED30009987-orf-1

>SMED30009987-orf-1 ID=SMED30009987-orf-1|Name=SMED30009987-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=220bp
MNKSTSGDEHGDNHSIDFYENSDQMKRYRTNYSRNQINRLEQEFRREKYL
SRLKRTELAKELGLKESTIKVWFQNRRMKEKRQLTTINIPQILANSDPFL
YSYLLDSARAYYNFTSQFGHSPAQPPSKFEAISTETALAAFMSTNKLMPY
HGVPNLSHVPAIKPNCSGECPTIMIPPVSRCYLDQHETQISTFPTQSNAC
VNIASIKKSEITFRPYMDS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR020479Homeobox_metazoa
IPR000047HTH_motif
IPR001356Homeobox_dom
IPR009057Homeobox-like_sf
IPR017970Homeobox_CS
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0043565sequence-specific DNA binding
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000047Helix-turn-helix motifPRINTSPR00031HTHREPRESSRcoord: 63..79
score: 53.91
coord: 54..63
score: 53.2
IPR020479Homeobox domain, metazoaPRINTSPR00024HOMEOBOXcoord: 62..72
score: 47.5
coord: 72..81
score: 80.28
coord: 47..58
score: 41.14
IPR001356Homeobox domainSMARTSM00389HOX_1coord: 25..87
e-value: 1.4E-22
score: 91.0
IPR001356Homeobox domainPFAMPF00046Homeodomaincoord: 26..82
e-value: 2.6E-20
score: 72.0
IPR001356Homeobox domainPROSITEPS50071HOMEOBOX_2coord: 23..83
score: 21.006
IPR001356Homeobox domainCDDcd00086homeodomaincoord: 26..83
e-value: 2.59932E-22
score: 83.832
NoneNo IPR availableGENE3DG3DSA:1.10.10.60coord: 5..85
e-value: 1.3E-23
score: 84.8
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..20
NoneNo IPR availablePANTHERPTHR46294FAMILY NOT NAMEDcoord: 17..191
IPR017970Homeobox, conserved sitePROSITEPS00027HOMEOBOX_1coord: 58..81
IPR009057Homeobox-like domain superfamilySUPERFAMILYSSF46689Homeodomain-likecoord: 12..83