Ras-related protein

Overview
NameRas-related protein
Smed IDSMED30009981
Length (bp)850
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ras-related protein (SMED30009981) t-SNE clustered cells

Violin plots show distribution of expression levels for Ras-related protein (SMED30009981) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ras-related protein (SMED30009981) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ras-related protein (SMED30009981) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30009981

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30009981h1SMcG0000040 SmedASXL_005725SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30009981h1SMcG0000040 dd_Smed_v4_6181_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30009981h1SMcG0000040 dd_Smed_v6_6181_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30009981h1SMcG0000040 dd_Smed_v4_6181_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ras-related protein vs. Ensembl Human
Match: RAB4A (RAB4A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9781])

HSP 1 Score: 251.521 bits (641), Expect = 1.450e-83
Identity = 121/214 (56.54%), Postives = 156/214 (72.90%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            MSE YD LFKFL+IGN+G GKSC+L+QFIE++F+ DS HTIGVEF SKII++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P        + C C
Sbjct:    6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRAQAPNAQECGC 218
[Close]
BLAST of Ras-related protein vs. Ensembl Human
Match: RAB4B (RAB4B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9782])

HSP 1 Score: 243.047 bits (619), Expect = 2.248e-80
Identity = 116/214 (54.21%), Postives = 153/214 (71.50%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            M+E YD LFKFL+IG++G GKSC+L+QFIE +F+ DS HTIGVEF S+++++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I+VIL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL+ +++    P    +  +  D     LR P        + C C
Sbjct:    1 MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDL-DPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMGSGIQYGDASLRQLRQPRSAQAVAPQPCGC 213
[Close]
BLAST of Ras-related protein vs. Ensembl Human
Match: RAB4B (RAB4B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9782])

HSP 1 Score: 243.047 bits (619), Expect = 2.248e-80
Identity = 116/214 (54.21%), Postives = 153/214 (71.50%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            M+E YD LFKFL+IG++G GKSC+L+QFIE +F+ DS HTIGVEF S+++++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I+VIL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL+ +++    P    +  +  D     LR P        + C C
Sbjct:    1 MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDL-DPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMGSGIQYGDASLRQLRQPRSAQAVAPQPCGC 213
[Close]
BLAST of Ras-related protein vs. Ensembl Human
Match: RAB4B-EGLN2 (RAB4B-EGLN2 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:44465])

HSP 1 Score: 243.047 bits (619), Expect = 2.248e-80
Identity = 116/214 (54.21%), Postives = 153/214 (71.50%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            M+E YD LFKFL+IG++G GKSC+L+QFIE +F+ DS HTIGVEF S+++++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I+VIL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL+ +++    P    +  +  D     LR P        + C C
Sbjct:    1 MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDL-DPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMGSGIQYGDASLRQLRQPRSAQAVAPQPCGC 213
[Close]
BLAST of Ras-related protein vs. Ensembl Human
Match: RAB14 (RAB14, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16524])

HSP 1 Score: 209.92 bits (533), Expect = 8.209e-68
Identity = 91/171 (53.22%), Postives = 132/171 (77.19%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 639
            Y ++FK+++IG+ GVGKSC+L+QF E++F  D  HTIGVEF ++II ++ +K+KLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D + L+    ++IL+GNK D  +  R+V++ E  QFA+EN L+F+E SA TGENV +AF+  A++I  N++
Sbjct:    8 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADL-EAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQ 177
[Close]
BLAST of Ras-related protein vs. Ensembl Celegans
Match: rab-14 (RAB family [Source:UniProtKB/TrEMBL;Acc:Q93874])

HSP 1 Score: 204.527 bits (519), Expect = 1.227e-65
Identity = 96/204 (47.06%), Postives = 136/204 (66.67%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE-TVLDHPVDDVNDFRSADIRRPYLRTPTESCRC 735
            Y ++FK+++IG+ GVGKSC+L+QF E++F  D  HTIGVEF ++II ++ +K+KLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D K L+     + L+GNK D  D+ R+V + E   FA+EN L F+E SA TG NV +AF+  A++I  N++   LD    D       ++ R       + C C
Sbjct:    8 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLADAKSLTNPNTAIFLIGNKADLEDQ-RDVPYEEAKAFAEENGLTFLECSAKTGSNVEDAFLETAKQIYQNIQDGSLDLNAADTGVQPKQNLPRAAENNGKKDCNC 210
[Close]
BLAST of Ras-related protein vs. Ensembl Celegans
Match: rab-14 (RAB family [Source:UniProtKB/TrEMBL;Acc:Q93874])

HSP 1 Score: 204.527 bits (519), Expect = 1.227e-65
Identity = 96/204 (47.06%), Postives = 136/204 (66.67%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE-TVLDHPVDDVNDFRSADIRRPYLRTPTESCRC 735
            Y ++FK+++IG+ GVGKSC+L+QF E++F  D  HTIGVEF ++II ++ +K+KLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D K L+     + L+GNK D  D+ R+V + E   FA+EN L F+E SA TG NV +AF+  A++I  N++   LD    D       ++ R       + C C
Sbjct:    8 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLADAKSLTNPNTAIFLIGNKADLEDQ-RDVPYEEAKAFAEENGLTFLECSAKTGSNVEDAFLETAKQIYQNIQDGSLDLNAADTGVQPKQNLPRAAENNGKKDCNC 210
[Close]
BLAST of Ras-related protein vs. Ensembl Celegans
Match: unc-108 (pep chromosome:WBcel235:I:3822883:3826514:1 gene:WBGene00006833.1 transcript:F53F10.4b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-108)

HSP 1 Score: 186.422 bits (472), Expect = 1.888e-58
Identity = 90/176 (51.14%), Postives = 130/176 (73.86%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNL-ETVLD 651
            Y +LFK+++IG++GVGKSC+L QF +++F+     TIGVEF +++++I  +++KLQIWDTAGQE FRS+T+SYYR A GALLVYD++ R++FN L+ WL D +Q S   ++++L+GNK D  +  REV   EG  FA+E+ L+F+ETSA T  NV EAFI+ A+ I   + E V D
Sbjct:   12 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVTIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTSWLEDARQHSNSNMVIMLIGNKSDL-EARREVKREEGEAFAREHGLVFMETSAKTAANVEEAFIDTAKEIYRKIQEGVFD 186
[Close]
BLAST of Ras-related protein vs. Ensembl Celegans
Match: unc-108 (pep chromosome:WBcel235:I:3824947:3826514:1 gene:WBGene00006833.1 transcript:F53F10.4a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-108)

HSP 1 Score: 186.037 bits (471), Expect = 2.255e-58
Identity = 90/176 (51.14%), Postives = 130/176 (73.86%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNL-ETVLD 651
            Y +LFK+++IG++GVGKSC+L QF +++F+     TIGVEF +++++I  +++KLQIWDTAGQE FRS+T+SYYR A GALLVYD++ R++FN L+ WL D +Q S   ++++L+GNK D  +  REV   EG  FA+E+ L+F+ETSA T  NV EAFI+ A+ I   + E V D
Sbjct:    3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVTIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTSWLEDARQHSNSNMVIMLIGNKSDL-EARREVKREEGEAFAREHGLVFMETSAKTAANVEEAFIDTAKEIYRKIQEGVFD 177
[Close]
BLAST of Ras-related protein vs. Ensembl Celegans
Match: F11A5.4 (pep chromosome:WBcel235:V:16195679:16196290:1 gene:WBGene00008672.1 transcript:F11A5.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F11A5.4)

HSP 1 Score: 164.851 bits (416), Expect = 2.897e-50
Identity = 87/171 (50.88%), Postives = 117/171 (68.42%), Query Frame = 1 
Query:  130 DHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTH--TIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNL 636
            DH+FK+++IG+ GVGKS +L +FI + F  DS H  T+G+EF  + + I  +KVKL +WDT GQERFRS+  SYYR A+GALLVYD++ RESF  L  WL D+++L    I+++L+GNK D  +  REV   EG  FA+E  L+F+E SA T E V EAF+N A  I   L
Sbjct:    4 DHVFKYVIIGDRGVGKSNLLLRFIGKPF--DSIHPSTLGIEFGFRNLEIDRKKVKLHVWDTCGQERFRSLVGSYYRHAIGALLVYDITSRESFYHLEHWLTDLQRLGDPDIVIVLIGNKSD-LEADREVRKEEGEAFAREFGLIFMEISAKTNEYVEEAFVNSAHEIYRKL 171
[Close]
BLAST of Ras-related protein vs. Ensembl Fly
Match: Rab4 (gene:FBgn0016701 transcript:FBtr0086829)

HSP 1 Score: 235.343 bits (599), Expect = 1.299e-77
Identity = 108/176 (61.36%), Postives = 143/176 (81.25%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET 642
            MSE YD+LFKFL+IG++G GKSC+L+ FIE +F+ DS+HTIGVEF S+I+++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD + R+SFN L+ WL D + L+   I+++LVGNK D  +E+R+V+F+E + FAQENEL+F+ETSA TGENV EAF+  ++ IL  +ET
Sbjct:    1 MSETYDYLFKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASPNIVILLVGNKKD-LEEARDVTFLEASTFAQENELIFLETSAKTGENVEEAFLKCSKTILAKIET 175
[Close]
BLAST of Ras-related protein vs. Ensembl Fly
Match: Rab4 (gene:FBgn0016701 transcript:FBtr0086830)

HSP 1 Score: 235.343 bits (599), Expect = 1.299e-77
Identity = 108/176 (61.36%), Postives = 143/176 (81.25%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET 642
            MSE YD+LFKFL+IG++G GKSC+L+ FIE +F+ DS+HTIGVEF S+I+++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD + R+SFN L+ WL D + L+   I+++LVGNK D  +E+R+V+F+E + FAQENEL+F+ETSA TGENV EAF+  ++ IL  +ET
Sbjct:    1 MSETYDYLFKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASPNIVILLVGNKKD-LEEARDVTFLEASTFAQENELIFLETSAKTGENVEEAFLKCSKTILAKIET 175
[Close]
BLAST of Ras-related protein vs. Ensembl Fly
Match: Rab14 (gene:FBgn0015791 transcript:FBtr0343678)

HSP 1 Score: 210.69 bits (535), Expect = 5.821e-68
Identity = 91/171 (53.22%), Postives = 132/171 (77.19%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 639
            Y+++FK+++IG+ GVGKSC+L+QF E++F  +  HTIGVEF ++II +  +K+KLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D + L+    ++ L+GNK D  + +REV++ E  +FA EN LMF+E SA+TG+NV EAF+  AR+I  N++
Sbjct:    8 YNYIFKYIIIGDMGVGKSCLLHQFTEKKFMANCPHTIGVEFGTRIIEVDDKKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDTRNLTNPSTVIFLIGNKSDL-ESTREVTYEEAKEFADENGLMFLEASAMTGQNVEEAFLETARKIYQNIQ 177
[Close]
BLAST of Ras-related protein vs. Ensembl Fly
Match: Rab14 (gene:FBgn0015791 transcript:FBtr0080626)

HSP 1 Score: 210.69 bits (535), Expect = 5.821e-68
Identity = 91/171 (53.22%), Postives = 132/171 (77.19%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 639
            Y+++FK+++IG+ GVGKSC+L+QF E++F  +  HTIGVEF ++II +  +K+KLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D + L+    ++ L+GNK D  + +REV++ E  +FA EN LMF+E SA+TG+NV EAF+  AR+I  N++
Sbjct:    8 YNYIFKYIIIGDMGVGKSCLLHQFTEKKFMANCPHTIGVEFGTRIIEVDDKKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDTRNLTNPSTVIFLIGNKSDL-ESTREVTYEEAKEFADENGLMFLEASAMTGQNVEEAFLETARKIYQNIQ 177
[Close]
BLAST of Ras-related protein vs. Ensembl Fly
Match: Rab14 (gene:FBgn0015791 transcript:FBtr0080627)

HSP 1 Score: 211.075 bits (536), Expect = 1.118e-67
Identity = 91/171 (53.22%), Postives = 132/171 (77.19%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 639
            Y+++FK+++IG+ GVGKSC+L+QF E++F  +  HTIGVEF ++II +  +K+KLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D + L+    ++ L+GNK D  + +REV++ E  +FA EN LMF+E SA+TG+NV EAF+  AR+I  N++
Sbjct:   32 YNYIFKYIIIGDMGVGKSCLLHQFTEKKFMANCPHTIGVEFGTRIIEVDDKKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDTRNLTNPSTVIFLIGNKSDL-ESTREVTYEEAKEFADENGLMFLEASAMTGQNVEEAFLETARKIYQNIQ 201
[Close]
BLAST of Ras-related protein vs. Ensembl Zebrafish
Match: rab4a (RAB4a, member RAS oncogene family [Source:NCBI gene;Acc:403031])

HSP 1 Score: 250.751 bits (639), Expect = 1.347e-83
Identity = 120/201 (59.70%), Postives = 154/201 (76.62%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP 717
            MSE YD LFKFL+IGN+G GKSC+L+QFIE++F+ DS HTIGVEF SKIIS+ ++ VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P
Sbjct:    1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKRFKDDSNHTIGVEFGSKIISVVNKFVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSP 200
[Close]
BLAST of Ras-related protein vs. Ensembl Zebrafish
Match: rab4b (RAB4B, member RAS oncogene family [Source:NCBI gene;Acc:445498])

HSP 1 Score: 244.973 bits (624), Expect = 3.283e-81
Identity = 116/214 (54.21%), Postives = 153/214 (71.50%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            MSE YD LFKFL+IG++G GKSC+L+QFIE +F+ DS HTIGVEF S+++++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL+ +E+    P    +  +  D     +R P        + C C
Sbjct:    1 MSETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARTLASPNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARSILNKIESGELDPERMGSGIQYGDASLRQIRQPRGSAAQTKQQCNC 213
[Close]
BLAST of Ras-related protein vs. Ensembl Zebrafish
Match: rab4b (RAB4B, member RAS oncogene family [Source:NCBI gene;Acc:445498])

HSP 1 Score: 244.973 bits (624), Expect = 3.283e-81
Identity = 116/214 (54.21%), Postives = 153/214 (71.50%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            MSE YD LFKFL+IG++G GKSC+L+QFIE +F+ DS HTIGVEF S+++++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL+ +E+    P    +  +  D     +R P        + C C
Sbjct:    1 MSETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARTLASPNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARSILNKIESGELDPERMGSGIQYGDASLRQIRQPRGSAAQTKQQCNC 213
[Close]
BLAST of Ras-related protein vs. Ensembl Zebrafish
Match: rab14 (RAB14, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-030826-20])

HSP 1 Score: 211.46 bits (537), Expect = 4.205e-68
Identity = 92/171 (53.80%), Postives = 132/171 (77.19%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 639
            Y ++FK+++IG+ GVGKSC+L+QF E++F  D  HTIGVEF ++II ++ +KVKLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D + L+    ++IL+GNK D  +  R+V++ E  QFA+EN L+F+E SA TGENV +AF+  A++I  N++
Sbjct:    8 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKVKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADL-EAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQ 177
[Close]
BLAST of Ras-related protein vs. Ensembl Zebrafish
Match: rab14l (RAB14, member RAS oncogene family, like [Source:ZFIN;Acc:ZDB-GENE-040426-1207])

HSP 1 Score: 209.92 bits (533), Expect = 1.905e-67
Identity = 90/171 (52.63%), Postives = 132/171 (77.19%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 639
            Y ++FK+++IG+ GVGKSC+L+QF E++F  D  HTIGVEF ++I+ ++ +K+KLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D + L+    ++IL+GNK D  +  R+V++ E  QFA+EN L+F+E SA TGENV +AF+  A++I  N++
Sbjct:    8 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIMEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADL-EAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQ 177
[Close]
BLAST of Ras-related protein vs. Ensembl Xenopus
Match: map4 (microtubule associated protein 4 [Source:Xenbase;Acc:XB-GENE-6259104])

HSP 1 Score: 243.432 bits (620), Expect = 1.848e-80
Identity = 112/176 (63.64%), Postives = 142/176 (80.68%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET 642
            MSE YD LFKFL+IG++G GKSC+L+QFIE +F+ DS HTIGVEF S+I+++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   II+IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL  +E+
Sbjct:    1 MSETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRIVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDIASRETYNALTNWLTDARTLASPNIIIILCGNKKDL-DADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILSKIES 175
[Close]
BLAST of Ras-related protein vs. Ensembl Xenopus
Match: map4 (microtubule associated protein 4 [Source:Xenbase;Acc:XB-GENE-6259104])

HSP 1 Score: 227.254 bits (578), Expect = 2.983e-74
Identity = 104/166 (62.65%), Postives = 134/166 (80.72%), Query Frame = 1 
Query:  145 FLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET 642
            FL+IG++G GKSC+L+QFIE +F+ DS HTIGVEF S+I+++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   II+IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL  +E+
Sbjct:    5 FLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRIVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDIASRETYNALTNWLTDARTLASPNIIIILCGNKKDL-DADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILSKIES 169
[Close]
BLAST of Ras-related protein vs. Ensembl Xenopus
Match: map4 (microtubule associated protein 4 [Source:Xenbase;Acc:XB-GENE-6259104])

HSP 1 Score: 195.667 bits (496), Expect = 4.183e-62
Identity = 96/176 (54.55%), Postives = 123/176 (69.89%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET 642
            MSE YD LFKFL+IG++G GKSC+L+QFIE +F+ DS HTIGVEF S+I+++  + VKLQIWDTAGQERF                      RE++N L+ WL D + L+   II+IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL  +E+
Sbjct:    1 MSETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRIVNVGGKSVKLQIWDTAGQERF---------------------SRETYNALTNWLTDARTLASPNIIIILCGNKKDL-DADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILSKIES 154
[Close]
BLAST of Ras-related protein vs. Ensembl Xenopus
Match: RAB2A (RAB2A, member RAS oncogene family [Source:NCBI gene;Acc:100038062])

HSP 1 Score: 186.808 bits (473), Expect = 2.520e-58
Identity = 94/197 (47.72%), Postives = 136/197 (69.04%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP 717
            Y +LFK+++IG++GVGKSC+L QF +++F+     TIGVEF +++I+I  +++KLQIWDTAGQE FRS+T+SYYR A GALLVYD++ R++FN L+ WL D +Q S   ++++L+ NK D  +  REV   EG  FA+E+ L+F+ETSA T  NV EAFIN A+ I   ++      V D+N+  +     P   TP
Sbjct:    3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIANKSDL-ESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQ----EGVFDINNEANGIKIGPQHSTP 194
[Close]
BLAST of Ras-related protein vs. Ensembl Xenopus
Match: hus1 (HUS1 checkpoint clamp component [Source:Xenbase;Acc:XB-GENE-983295])

HSP 1 Score: 186.037 bits (471), Expect = 5.121e-58
Identity = 90/174 (51.72%), Postives = 129/174 (74.14%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVL 648
            Y +LFK+++IG++GVGKSC+L QF +++F+     TIGVEF +++I+I  + +KLQIWDTAGQE FRS+T+SYYR A GALLVYD++ RE+F+ L+ WL D +Q S   +++IL+GNK D  +  R+VS  EG  FA+E+ L+F+ETSA T  NV EAFI+ A+ I   ++  L
Sbjct:    3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMINIDGKPIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFSHLTSWLEDARQHSSSNMVIILIGNKSDL-ESRRDVSREEGEAFAREHGLIFMETSAKTAANVEEAFIDTAKEIYKKIQQGL 175
[Close]
BLAST of Ras-related protein vs. Ensembl Mouse
Match: Rab4a (RAB4A, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:105069])

HSP 1 Score: 250.751 bits (639), Expect = 2.206e-83
Identity = 121/214 (56.54%), Postives = 156/214 (72.90%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            MSE YD LFKFL+IGN+G GKSC+L+QFIE++F+ DS HTIGVEF SKII++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P        + C C
Sbjct:    6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVLILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFMQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRTQAPSAQECGC 218
[Close]
BLAST of Ras-related protein vs. Ensembl Mouse
Match: Rab4a (RAB4A, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:105069])

HSP 1 Score: 250.751 bits (639), Expect = 2.206e-83
Identity = 121/214 (56.54%), Postives = 156/214 (72.90%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            MSE YD LFKFL+IGN+G GKSC+L+QFIE++F+ DS HTIGVEF SKII++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P        + C C
Sbjct:    6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVLILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFMQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRTQAPSAQECGC 218
[Close]
BLAST of Ras-related protein vs. Ensembl Mouse
Match: Rab4b (RAB4B, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:105071])

HSP 1 Score: 244.588 bits (623), Expect = 4.968e-81
Identity = 117/214 (54.67%), Postives = 154/214 (71.96%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            M+E YD LFKFL+IG++G GKSC+L+QFIE +F+ DS HTIGVEF S+++++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I+VIL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL+ +++    P    +  +  DI    LR P        + C C
Sbjct:    1 MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDL-DPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMGSGIQYGDISLRQLRQPRSAQAVAPQPCGC 213
[Close]
BLAST of Ras-related protein vs. Ensembl Mouse
Match: Rab14 (RAB14, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:1915615])

HSP 1 Score: 210.69 bits (535), Expect = 8.163e-68
Identity = 91/171 (53.22%), Postives = 132/171 (77.19%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 639
            Y ++FK+++IG+ GVGKSC+L+QF E++F  D  HTIGVEF ++II ++ +K+KLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D + L+    ++IL+GNK D  +  R+V++ E  QFA+EN L+F+E SA TGENV +AF+  A++I  N++
Sbjct:    8 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADL-EAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQ 177
[Close]
BLAST of Ras-related protein vs. Ensembl Mouse
Match: Rab2a (RAB2A, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:1928750])

HSP 1 Score: 188.734 bits (478), Expect = 3.709e-59
Identity = 92/176 (52.27%), Postives = 130/176 (73.86%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNL-ETVLD 651
            Y +LFK+++IG++GVGKSC+L QF +++F+     TIGVEF +++I+I  +++KLQIWDTAGQE FRS+T+SYYR A GALLVYD++ R++FN L+ WL D +Q S   ++++L+GNK D  +  REV   EG  FA+E+ L+F+ETSA T  NV EAFIN A+ I   + E V D
Sbjct:    3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSD-LESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFD 177
[Close]
BLAST of Ras-related protein vs. UniProt/SwissProt
Match: sp|P20338|RAB4A_HUMAN (Ras-related protein Rab-4A OS=Homo sapiens OX=9606 GN=RAB4A PE=1 SV=3)

HSP 1 Score: 251.521 bits (641), Expect = 6.962e-83
Identity = 121/214 (56.54%), Postives = 156/214 (72.90%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            MSE YD LFKFL+IGN+G GKSC+L+QFIE++F+ DS HTIGVEF SKII++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P        + C C
Sbjct:    6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRAQAPNAQECGC 218
[Close]
BLAST of Ras-related protein vs. UniProt/SwissProt
Match: sp|Q2TBH7|RAB4A_BOVIN (Ras-related protein Rab-4A OS=Bos taurus OX=9913 GN=RAB4A PE=2 SV=3)

HSP 1 Score: 251.136 bits (640), Expect = 8.289e-83
Identity = 121/214 (56.54%), Postives = 156/214 (72.90%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            MSE YD LFKFL+IGN+G GKSC+L+QFIE++F+ DS HTIGVEF SKII++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P        + C C
Sbjct:    6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKD-LDTDREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRAQAPSAQECGC 218
[Close]
BLAST of Ras-related protein vs. UniProt/SwissProt
Match: sp|Q6PHI9|RAB4A_DANRE (Ras-related protein Rab-4A OS=Danio rerio OX=7955 GN=rab4a PE=2 SV=2)

HSP 1 Score: 250.751 bits (639), Expect = 1.017e-82
Identity = 120/201 (59.70%), Postives = 154/201 (76.62%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP 717
            MSE YD LFKFL+IGN+G GKSC+L+QFIE++F+ DS HTIGVEF SKIIS+ ++ VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P
Sbjct:    1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKRFKDDSNHTIGVEFGSKIISVVNKFVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSP 200
[Close]
BLAST of Ras-related protein vs. UniProt/SwissProt
Match: sp|P05714|RAB4A_RAT (Ras-related protein Rab-4A OS=Rattus norvegicus OX=10116 GN=Rab4a PE=1 SV=3)

HSP 1 Score: 250.751 bits (639), Expect = 1.150e-82
Identity = 121/214 (56.54%), Postives = 156/214 (72.90%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            MSE YD LFKFL+IGN+G GKSC+L+QFIE++F+ DS HTIGVEF SKII++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P        + C C
Sbjct:    6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFMQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRTQAPSAQECGC 218
[Close]
BLAST of Ras-related protein vs. UniProt/SwissProt
Match: sp|P56371|RAB4A_MOUSE (Ras-related protein Rab-4A OS=Mus musculus OX=10090 GN=Rab4a PE=1 SV=2)

HSP 1 Score: 250.751 bits (639), Expect = 1.543e-82
Identity = 121/214 (56.54%), Postives = 156/214 (72.90%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            MSE YD LFKFL+IGN+G GKSC+L+QFIE++F+ DS HTIGVEF SKII++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P        + C C
Sbjct:    6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVLILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFMQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRTQAPSAQECGC 218
[Close]
BLAST of Ras-related protein vs. TrEMBL
Match: A0A1S3Q5W3 (ras-related protein Rab-4A isoform X2 OS=Salmo salar OX=8030 GN=LOC106589656 PE=4 SV=1)

HSP 1 Score: 253.062 bits (645), Expect = 3.917e-81
Identity = 123/214 (57.48%), Postives = 159/214 (74.30%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            MSE YD LFKFL+IGN+G GKSC+L+QFIE++F+ DS HTIGVEF SKII++ ++ VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+ LD P    +  +  D     LR+P        + C C
Sbjct:    1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKRFKDDSNHTIGVEFGSKIINVVNKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESELD-PERMGSGIQYGDAALRQLRSPRRGQAESAQECGC 212
[Close]
BLAST of Ras-related protein vs. TrEMBL
Match: A0A553Q7X8 (Uncharacterized protein OS=Danionella translucida OX=623744 GN=DNTS_001919 PE=4 SV=1)

HSP 1 Score: 252.292 bits (643), Expect = 7.542e-81
Identity = 122/214 (57.01%), Postives = 157/214 (73.36%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            MSE YD LFKFL+IGN+G GKSC+L+QFIE++F+ DS HTIGVEF SKIIS+ ++ VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P        + C C
Sbjct:    1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKRFKDDSNHTIGVEFGSKIISVVNKSVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRAQAESVQECGC 213
[Close]
BLAST of Ras-related protein vs. TrEMBL
Match: A0A455AMG0 (ras-related protein Rab-4A isoform X4 OS=Physeter macrocephalus OX=9755 GN=RAB4A PE=4 SV=1)

HSP 1 Score: 251.906 bits (642), Expect = 1.203e-80
Identity = 118/181 (65.19%), Postives = 148/181 (81.77%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHP 657
            MSE YD LFKFL+IGN+G GKSC+L+QFIE++F+ DS HTIGVEF SKII++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I+VIL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+V  HP
Sbjct:    6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVVILCGNKKDL-DADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESV--HP 183
[Close]
BLAST of Ras-related protein vs. TrEMBL
Match: Q53GC2 (RAB4A, member RAS oncogene family variant (Fragment) OS=Homo sapiens OX=9606 PE=2 SV=1)

HSP 1 Score: 251.906 bits (642), Expect = 1.236e-80
Identity = 121/214 (56.54%), Postives = 156/214 (72.90%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            MSE YD LFKFL+IGN+G GKSC+L+QFIE++F+ DS HTIGVEF SKII++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P        + C C
Sbjct:    6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKGDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRAQAPNAQECGC 218
[Close]
BLAST of Ras-related protein vs. TrEMBL
Match: A0A2Y9SBZ8 (ras-related protein Rab-4A isoform X2 OS=Physeter macrocephalus OX=9755 GN=RAB4A PE=4 SV=1)

HSP 1 Score: 251.906 bits (642), Expect = 1.263e-80
Identity = 122/214 (57.01%), Postives = 156/214 (72.90%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            MSE YD LFKFL+IGN+G GKSC+L+QFIE++F+ DS HTIGVEF SKII++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I+VIL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P        + C C
Sbjct:    6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVVILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRAQAPSAQECGC 218
[Close]
BLAST of Ras-related protein vs. Ensembl Cavefish
Match: rab4a (RAB4A, member RAS oncogene family [Source:NCBI gene;Acc:103032660])

HSP 1 Score: 249.98 bits (637), Expect = 2.558e-83
Identity = 121/214 (56.54%), Postives = 157/214 (73.36%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            MSE YD LFKFL+IGN+G GKSC+L+QFIE++F+ DS HTIGVEF SKII++ ++ VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P        + C C
Sbjct:    1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVVNKFVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRAQAESVQECGC 213
[Close]
BLAST of Ras-related protein vs. Ensembl Cavefish
Match: rab4b (ras-related protein Rab-4B [Source:NCBI gene;Acc:103022831])

HSP 1 Score: 246.128 bits (627), Expect = 9.875e-82
Identity = 117/214 (54.67%), Postives = 153/214 (71.50%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            MSE YD LFKFL+IG++G GKSC+L+QFIE +F+ DS HTIGVEF S+++++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL+ +E+    P    +  +  D     LR P        + C C
Sbjct:    1 MSETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARTLASPNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIESGELDPERMGSGIQYGDASLRQLRQPRGTAAQTKQQCNC 213
[Close]
BLAST of Ras-related protein vs. Ensembl Cavefish
Match: rab14 (ras-related protein Rab-14 [Source:NCBI gene;Acc:103026976])

HSP 1 Score: 211.46 bits (537), Expect = 3.564e-68
Identity = 92/171 (53.80%), Postives = 132/171 (77.19%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 639
            Y ++FK+++IG+ GVGKSC+L+QF E++F  D  HTIGVEF ++II ++ +KVKLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D + L+    ++IL+GNK D  +  R+V++ E  QFA+EN L+F+E SA TGENV +AF+  A++I  N++
Sbjct:    8 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKVKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADL-EAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQ 177
[Close]
BLAST of Ras-related protein vs. Ensembl Cavefish
Match: ENSAMXT00000039673.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000139.1:3081649:3095559:1 gene:ENSAMXG00000040126.1 transcript:ENSAMXT00000039673.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 211.46 bits (537), Expect = 1.989e-67
Identity = 91/171 (53.22%), Postives = 131/171 (76.61%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 639
            Y ++FK+++IG+ GVGKSC+L+QF E++F  D  HTIGVEF ++II +  +K+KLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D + L+    ++IL+GNK D  +  R+V++ E  QFA+EN L+F+E SA TGENV +AF+  A++I  N++
Sbjct:   65 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVNGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADL-EAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQ 234
[Close]
BLAST of Ras-related protein vs. Ensembl Cavefish
Match: rab4b (ras-related protein Rab-4B [Source:NCBI gene;Acc:103022831])

HSP 1 Score: 194.512 bits (493), Expect = 6.915e-62
Identity = 94/183 (51.37%), Postives = 124/183 (67.76%), Query Frame = 1 
Query:  208 QFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
              + DS HTIGVEF S+++++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL+ +E+    P    +  +  D     LR P        + C C
Sbjct:    9 HIKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARTLASPNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIESGELDPERMGSGIQYGDASLRQLRQPRGTAAQTKQQCNC 190
[Close]
BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Match: rab4b (RAB4B, member RAS oncogene family [Source:NCBI gene;Acc:445498])

HSP 1 Score: 229.18 bits (583), Expect = 1.098e-75
Identity = 113/199 (56.78%), Postives = 145/199 (72.86%), Query Frame = 1 
Query:  130 DHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVS--DRESFNGLSKWLIDVKQLSGDGIIVILVGNKID-RPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP 717
            D LFKFL+IG++G GKSC+L+QFIE +F+ DS HTIGVEF SK+++   + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++   RE++N L+ WL D + L+   I +IL GNK D  PD  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL+ +E+    P    +  +  D     LR P
Sbjct:   10 DFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSKVVNTGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSGSRETYNALTNWLADARTLASPNIAIILCGNKKDLEPD--REVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIESGELDPERMGSGIQYGDSTLRQLRQP 206
[Close]
BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002219.1 (pep scaffold:Pmarinus_7.0:GL483980:50:9020:-1 gene:ENSPMAG00000002006.1 transcript:ENSPMAT00000002219.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 211.075 bits (536), Expect = 1.013e-68
Identity = 100/213 (46.95%), Postives = 144/213 (67.61%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP----------TESCRC 735
            Y ++FK+++IG+ GVGKSC+L+QF E++F  D  HTIGVEF ++II ++ +KVKLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D + L+    ++ L+GNK D  +  R+V++ E  QFA+EN L+F+E SA TG+NV EAF+  A++I  N++   D  + D+N   S    +P    P           +SC C
Sbjct:    8 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKVKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKADL-EAQRDVTYEEAKQFAEENGLLFLEASAKTGDNVEEAFLETAKKIYQNIQ---DGSL-DLNAAESGVQHKPATPQPGRLASDAQPAKDSCSC 215
[Close]
BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Match: RAB2B (RAB2B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:20246])

HSP 1 Score: 192.586 bits (488), Expect = 2.031e-61
Identity = 95/183 (51.91%), Postives = 133/183 (72.68%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVND 675
            Y +LFK+++IG++GVGKSC+L QF +++F+     TIGVEF +++I+I  ++VKLQIWDTAGQE FRS+T+SYYR A GALLVYD++ R++FN L+ WL D +Q S   ++++L+GNK D  +  REV   EG  FA+E+ L+F+ETSA T  NV EAFIN AR I   ++      V DVN+
Sbjct:    8 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMIAIGGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTAWLEDARQHSNSNMVIMLIGNKSDL-ESRREVKCEEGEAFAREHGLVFMETSAKTAANVEEAFINTAREIYEKIQ----EGVFDVNN 185
[Close]
BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Match: rab2a (RAB2A, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-011212-2])

HSP 1 Score: 189.119 bits (479), Expect = 3.550e-60
Identity = 93/176 (52.84%), Postives = 130/176 (73.86%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNL-ETVLD 651
            Y +LFK+++IG++GVGKSC+L QF +++F+     TIGVEF +++I+I  ++VKLQIWDTAGQE FRS+T+SYYR A GALLVYD++ R++FN L+ WL D +Q S   ++++L+GNK D  +  REV   EG  FA+E+ L+F+ETSA T  NV EAFIN A+ I   + E V D
Sbjct:    3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSD-LESRREVKREEGEAFAREHGLVFMETSAKTASNVEEAFINTAKEIYEKIQEGVFD 177
[Close]
BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Match: RAB2B (RAB2B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:20246])

HSP 1 Score: 187.578 bits (475), Expect = 6.092e-60
Identity = 93/176 (52.84%), Postives = 130/176 (73.86%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNL-ETVLD 651
            Y +LFK+++IG++GVGKSC+L QF +++F+     TIGVEF +++I+I  ++VKLQIWDTAGQE FRS+T+SYYR A GALLVYD++ R++FN L+ WL D +Q S   +I++L+GNK D  +  R+V   EG  FA+E+ L+F+ETSA T  NV EAFIN A+ I   + E V D
Sbjct:    8 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMINIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMIIMLIGNKSD-LESRRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKEIYQRIHEGVFD 182
[Close]
BLAST of Ras-related protein vs. Ensembl Yeast
Match: YPT1 (Rab family GTPase; involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by type II protein geranylgeranyltransferase (Bet2p-Bet4p); binds to unspliced HAC1 mRNA; regulates the unfolded protein response (UPR) by promoting the decay of HAC1 RNA; localizes to the early Golgi, the transitional Golgi and ER membranes, pre-autophagosomal structures, and cytoplasmic vesicles [Source:SGD;Acc:S000001856])

HSP 1 Score: 176.022 bits (445), Expect = 2.974e-55
Identity = 84/174 (48.28%), Postives = 123/174 (70.69%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNL 636
            M+  YD+LFK LLIGNSGVGKSC+L +F ++ +  D   TIGV+F  K + +  + VKLQIWDTAGQERFR++T SYYR + G ++VYDV+D+ESFNG+  WL ++ + +   ++ +LVGNK D  D+ R V +    +FA  N++ F+ETSA+   NV +AF+ +AR+I  ++
Sbjct:    1 MNSEYDYLFKLLLIGNSGVGKSCLLLRFSDDTYTNDYISTIGVDFKIKTVELDGKTVKLQIWDTAGQERFRTITSSYYRGSHGIIIVYDVTDQESFNGVKMWLQEIDRYATSTVLKLLVGNKCDLKDK-RVVEYDVAKEFADANKMPFLETSALDSTNVEDAFLTMARQIKESM 173
[Close]
BLAST of Ras-related protein vs. Ensembl Yeast
Match: YPT31 (Rab family GTPase; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; YPT31 has a paralog, YPT32, that arose from the whole genome duplication; localizes to the transitional and late Golgi [Source:SGD;Acc:S000000833])

HSP 1 Score: 171.785 bits (434), Expect = 2.029e-53
Identity = 82/159 (51.57%), Postives = 114/159 (71.70%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAF 603
            YD LFK +LIG+SGVGKS +L++F + +F MDS  TIGVEFA++ + I  +++K QIWDTAGQER+R++T +YYR AVGAL+VYD+S   S+   + WL ++++ + D + V L+GNK D     R V   E   FAQEN+L+F ETSA+  ENV +AF
Sbjct:   10 YDLLFKIVLIGDSGVGKSNLLSRFTKNEFNMDSKSTIGVEFATRTLEIDGKRIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYENCNHWLSELRENADDNVAVGLIGNKSDLA-HLRAVPTEESKTFAQENQLLFTETSALNSENVDKAF 167
[Close]
BLAST of Ras-related protein vs. Ensembl Yeast
Match: YPT32 (Rab family GTPase involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; protein abundance increases in response to DNA replication stress; YPT32 has a paralog, YPT31, that arose from the whole genome duplication [Source:SGD;Acc:S000003178])

HSP 1 Score: 168.318 bits (425), Expect = 3.876e-52
Identity = 83/179 (46.37%), Postives = 123/179 (68.72%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVD 663
            YD+LFK +LIG+SGVGKS +L++F  ++F ++S  TIGVEFA++ I + ++K+K QIWDTAGQER+R++T +YYR AVGAL+VYD+S   S+   + WL ++++ + D + V L+GNK D     R V   E   FA EN+++F ETSA+  +NV +AF  +   I+   + V  H VD
Sbjct:   10 YDYLFKIVLIGDSGVGKSNLLSRFTTDEFNIESKSTIGVEFATRTIEVENKKIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYENCNHWLTELRENADDNVAVGLIGNKSDLA-HLRAVPTDEAKNFAMENQMLFTETSALNSDNVDKAFREL---IVAIFQMVSKHQVD 184
[Close]
BLAST of Ras-related protein vs. Ensembl Yeast
Match: SEC4 (Rab family GTPase; essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane [Source:SGD;Acc:S000001889])

HSP 1 Score: 157.147 bits (396), Expect = 7.532e-48
Identity = 78/172 (45.35%), Postives = 116/172 (67.44%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET 642
            YD + K LLIG+SGVGKSC+L +F+E++F      TIG++F  K + I  +KVKLQ+WDTAGQERFR++T +YYR A+G +LVYDV+D  +F  + +W   V + + D   ++LVGNK D   E+R V+  +G   A+E  + FIE+SA   +NV+E F  +A+ I   +++
Sbjct:   17 YDSIMKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDINGKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHANDEAQLLLVGNKSDM--ETRVVTADQGEALAKELGIPFIESSAKNDDNVNEIFFTLAKLIQEKIDS 186
[Close]
BLAST of Ras-related protein vs. Ensembl Yeast
Match: VPS21 (Endosomal Rab family GTPase; required for endocytic transport and sorting of vacuolar hydrolases; required for endosomal localization of the CORVET complex; required with YPT52 for MVB biogenesis and sorting; involved in autophagy and ionic stress tolerance; geranylgeranylation required for membrane association; protein abundance increases in response to DNA replication stress; mammalian Rab5 homolog; VPS21 has a paralog, YPT53, that arose from the whole genome duplication [Source:SGD;Acc:S000005615])

HSP 1 Score: 135.191 bits (339), Expect = 1.891e-39
Identity = 69/163 (42.33%), Postives = 102/163 (62.58%), Query Frame = 1 
Query:  142 KFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDES--REVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 624
            K +L+G + VGKS ++ +F+   F  +   TIG  F ++ ++I    VK +IWDTAGQERF S+   YYR A  AL+VYDV+  +SF     W+ ++ + +   II+ LVGNKID   E   R+V+  EG + A+E  L+F ETSA TGENV++ F+ +  +I
Sbjct:    9 KLVLLGEAAVGKSSIVLRFVSNDFAENKEPTIGAAFLTQRVTINEHTVKFEIWDTAGQERFASLAPMYYRNAQAALVVYDVTKPQSFIKARHWVKELHEQASKDIIIALVGNKIDMLQEGGERKVAREEGEKLAEEKGLLFFETSAKTGENVNDVFLGIGEKI 171
[Close]
BLAST of Ras-related protein vs. Ensembl Nematostella
Match: EDO43047 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZT6])

HSP 1 Score: 245.358 bits (625), Expect = 5.900e-82
Identity = 113/176 (64.20%), Postives = 144/176 (81.82%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET 642
            MSE YD LFKFL+IG++G GKSC+L+QFIE +F+ DS+HTIGVEF SKI+++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD+S RE+FN L+ WL D + L+   I++ILVGNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV E F+  +R IL+ +E+
Sbjct:    1 MSETYDFLFKFLVIGSAGTGKSCILHQFIEGKFKQDSSHTIGVEFGSKIVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDISSRETFNSLTNWLTDARTLASPNIVIILVGNKKDL-DADREVTFLEASRFAQENELMFLETSALTGENVEEGFLKCSRTILNKIES 175
[Close]
BLAST of Ras-related protein vs. Ensembl Nematostella
Match: EDO43319 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ04])

HSP 1 Score: 209.92 bits (533), Expect = 6.781e-68
Identity = 91/171 (53.22%), Postives = 130/171 (76.02%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 639
            Y ++FK+++IG+ GVGKSC+L+QF E++F  D  HTIGVEF ++II ++ +K+KLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D + L+    ++ L+GNK D  D  R+V++ E  QFA+EN L+F E SA TGENV +AF+  A++I  N++
Sbjct:    9 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDL-DAQRDVTYEEAKQFAEENGLLFCEASAKTGENVEDAFLETAKKIYQNIQ 178
[Close]
BLAST of Ras-related protein vs. Ensembl Nematostella
Match: EDO36687 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHU3])

HSP 1 Score: 187.963 bits (476), Expect = 1.889e-59
Identity = 88/171 (51.46%), Postives = 128/171 (74.85%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 639
            Y +LFK+++IG++GVGKSC+L QF +++F+     TIGVEF +++I+I  +++KLQIWDTAGQE FRS+T+SYYR A GALLVYD++ R++FN L+ WL D +Q S   ++++L+GNK D  +  R+V   EG  FA+E+ L+F+ETSA T  NV EAFIN A+ I   ++
Sbjct:    3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMVIMLIGNKSDL-EARRDVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQ 172
[Close]
BLAST of Ras-related protein vs. Ensembl Nematostella
Match: EDO43129 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZN1])

HSP 1 Score: 174.481 bits (441), Expect = 3.112e-54
Identity = 84/164 (51.22%), Postives = 119/164 (72.56%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVAR 618
            YD+LFK LLIG+SGVGKSC+L +F+++  R     TIGV+F  K + +  + VKLQIWDTAGQERFR++T SYYR A G ++VYD++ RES+N L KWL++V+  + +G+ +ILVGNKID  D  REV      ++A  +++ F+ETSA   +NV EAF+ ++R
Sbjct:   13 YDYLFKILLIGDSGVGKSCLLLRFVDDSHRESYQTTIGVDFKIKTMRVDGKVVKLQIWDTAGQERFRTITSSYYRGAHGVMIVYDITKRESYNNLHKWLMEVETYASEGVHMILVGNKIDL-DTDREVQPDAAQEWAALHDMPFVETSAKGAKNVKEAFLVLSR 175
[Close]
BLAST of Ras-related protein vs. Ensembl Nematostella
Match: EDO33171 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST02])

HSP 1 Score: 164.466 bits (415), Expect = 3.338e-50
Identity = 83/182 (45.60%), Postives = 121/182 (66.48%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILH--NLETVLDHPVDD 666
            YD+LFK +LIG+SGVGKS +L++F   +F ++S  TIGVEFA++ I +  + +K QIWDTAGQER+R++T +YYR AVGALLVYD++   ++  + +WL +++  +   I+++LVGNK D     R V   E   FA++N L FIETSA+   NV  AF N+   I H  + + + D P  D
Sbjct:    8 YDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLR-HLRAVPTDEAKAFAEKNGLSFIETSALDSTNVEVAFHNILTEIYHIVSQKQIHDSPSSD 188
[Close]
BLAST of Ras-related protein vs. Ensembl Medaka
Match: rab4a (RAB4A, member RAS oncogene family [Source:NCBI gene;Acc:101158840])

HSP 1 Score: 249.21 bits (635), Expect = 4.532e-83
Identity = 122/214 (57.01%), Postives = 158/214 (73.83%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            MSE YD LFKFL+IGN+G GKSC+L+QFIE++F+ +S HTIGVEF SKIIS+ ++ VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P       T+ C C
Sbjct:    1 MSESYDFLFKFLVIGNAGTGKSCLLHQFIEKRFKDESNHTIGVEFGSKIISVVNKMVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTTWLSDARMLASQNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRAQPQGTQECGC 213
[Close]
BLAST of Ras-related protein vs. Ensembl Medaka
Match: rab4b (ras-related protein Rab-4B [Source:NCBI gene;Acc:101159839])

HSP 1 Score: 244.202 bits (622), Expect = 4.717e-81
Identity = 117/214 (54.67%), Postives = 152/214 (71.03%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            MSE YD LFKFL+IG++G GKSC+L+QFIE +F+ DS HTIGVEF S++I++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N LS WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV E F+  AR IL+ +++    P    +  +  D     LR P        + C C
Sbjct:    1 MSETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVINVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALSNWLTDARTLASPNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEGFLKCARTILNKIDSGELDPERMGSGIQYGDASLRQLRQPRGTTTQNKQQCNC 213
[Close]
BLAST of Ras-related protein vs. Ensembl Medaka
Match: rab4b (ras-related protein Rab-4B [Source:NCBI gene;Acc:101159839])

HSP 1 Score: 232.646 bits (592), Expect = 3.603e-76
Identity = 114/214 (53.27%), Postives = 151/214 (70.56%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            +S+ Y  LFKFL+IG++G GKSC+L+QFIE +F+ DS HTIGVEF S++I++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N LS WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV E F+  AR IL+ +++    P    +  +  D     LR P        + C C
Sbjct:   26 LSQPY-FLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVINVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALSNWLTDARTLASPNIVIILCGNKKDL-DADREVTFLEASRFAQENELMFLETSALTGENVEEGFLKCARTILNKIDSGELDPERMGSGIQYGDASLRQLRQPRGTTTQNKQQCNC 237
[Close]
BLAST of Ras-related protein vs. Ensembl Medaka
Match: rab4b (ras-related protein Rab-4B [Source:NCBI gene;Acc:101159839])

HSP 1 Score: 232.261 bits (591), Expect = 7.613e-76
Identity = 112/207 (54.11%), Postives = 147/207 (71.01%), Query Frame = 1 
Query:  136 LFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 735
            LFKFL+IG++G GKSC+L+QFIE +F+ DS HTIGVEF S++I++  + VKLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N LS WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV E F+  AR IL+ +++    P    +  +  D     LR P        + C C
Sbjct:   39 LFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVINVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALSNWLTDARTLASPNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEGFLKCARTILNKIDSGELDPERMGSGIQYGDASLRQLRQPRGTTTQNKQQCNC 244
[Close]
BLAST of Ras-related protein vs. Ensembl Medaka
Match: ENSORLT00000033612.1 (ras-related protein Rab-14 [Source:NCBI gene;Acc:101167092])

HSP 1 Score: 212.616 bits (540), Expect = 1.119e-68
Identity = 103/213 (48.36%), Postives = 144/213 (67.61%), Query Frame = 1 
Query:  127 YDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYL----------RTPTESCRC 735
            Y  +FK+++IG+ GVGKSC+L+QF E++F  D  HTIGVEF ++I+ +  +KVKLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D + L+    ++IL+GNK D  +  R+V++ E  QFA EN L+F+E SA TGENV EAF+  A+RI  N++   D  + D+N   S    +P            ++P ESC C
Sbjct:    8 YSFIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIMEVHGQKVKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADL-EAQRDVTYEEAKQFADENGLLFLEASAKTGENVEEAFLEAAKRIYQNIQ---DGSL-DLNAAESGVQHKPSAPQGGRLNSDSQSPKESCSC 215
[Close]
BLAST of Ras-related protein vs. Planmine SMEST
Match: SMESG000044147.1 (SMESG000044147.1)

HSP 1 Score: 426.787 bits (1096), Expect = 2.762e-153
Identity = 207/207 (100.00%), Postives = 207/207 (100.00%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTPTESCRC 735
            MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTPTESCRC
Sbjct:    1 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTPTESCRC 207
[Close]
BLAST of Ras-related protein vs. Planmine SMEST
Match: SMESG000044147.1 (SMESG000044147.1)

HSP 1 Score: 355.91 bits (912), Expect = 7.088e-126
Identity = 173/173 (100.00%), Postives = 173/173 (100.00%), Query Frame = 1 
Query:  217 MDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTPTESCRC 735
            MDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTPTESCRC
Sbjct:    1 MDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTPTESCRC 173
[Close]
BLAST of Ras-related protein vs. Planmine SMEST
Match: SMESG000044157.1 (SMESG000044157.1)

HSP 1 Score: 226.483 bits (576), Expect = 5.410e-74
Identity = 111/203 (54.68%), Postives = 149/203 (73.40%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPD--ESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET--VLDHPVDDVNDFRSADIRRPYLR 711
            M+E Y+ LFKFL+IGN+GVGKSC+L+ FIE++ + +S HTIGVEFASKII + +R +KLQIWDTAGQERFRSV +SYYR A GAL+VYDV++R+SFN +  WL D K L+G  +  ILVGNK D  D   SREVS+ E   FA+ENE+ F ETSAV+GE++ + FI+ AR ++   E+  + D+   + +   S DIR+ + R
Sbjct:    1 MNEQYEFLFKFLIIGNAGVGKSCILHHFIEQKVKENSVHTIGVEFASKIIQVNNRTIKLQIWDTAGQERFRSVARSYYRGASGALVVYDVTNRDSFNAIINWLSDAKSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFARENEMQFYETSAVSGEHIDDVFIDCARAVVCKWESNDLSDNIAQNSSSQNSGDIRKRWNR 203
[Close]
BLAST of Ras-related protein vs. Planmine SMEST
Match: SMESG000081610.1 (SMESG000081610.1)

HSP 1 Score: 215.312 bits (547), Expect = 1.042e-69
Identity = 99/176 (56.25%), Postives = 134/176 (76.14%), Query Frame = 1 
Query:  115 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET 642
            M + +D+L KFL+IGN+  GKSC+L +F E +F  +  HTIGVEFASKII +A++++KLQIWDTAGQERFRSVT+SYYR A GALLVYD+++R SF  L KWL D + L+   + ++LVGNK D  + +REV+  E  +FA EN ++F ETSA T ENV++AFIN +R IL N+++
Sbjct:    1 MQDYFDYLLKFLIIGNTNTGKSCLLLRFTENKFDNNKQHTIGVEFASKIICVANKRLKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITNRSSFVSLEKWLADTRHLADPDVTIVLVGNKCD-LEHNREVTKAEAEKFANENNILFFETSACTSENVNDAFINCSRTILSNIDS 175
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BLAST of Ras-related protein vs. Planmine SMEST
Match: SMESG000024495.1 (SMESG000024495.1)

HSP 1 Score: 204.527 bits (519), Expect = 1.219e-65
Identity = 94/174 (54.02%), Postives = 131/174 (75.29%), Query Frame = 1 
Query:  118 SEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 639
            SE Y ++FK+++IG+ GVGKSC+L+QF E +F  D  HTIGVEF +KII ++  KVKLQIWDTAGQERFR+VT+SYYR A GA+LVYD++ + +FN +  WL D + L+    + IL+GNK D  +E+REVSF +G + A+EN + F+E SA TGE+V +AFI  AR+I  +++
Sbjct:    3 SEAYSYIFKYIIIGDMGVGKSCLLHQFTESKFLPDCPHTIGVEFGTKIIEVSGEKVKLQIWDTAGQERFRAVTRSYYRGAAGAILVYDITRKATFNRVHSWLSDARSLTSPQTVFILIGNKGDL-NENREVSFEDGKELAEENGMFFLECSARTGEHVEDAFIETARKIYQHIQ 175
The following BLAST results are available for this feature:
BLAST of Ras-related protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RAB4A1.450e-8356.54RAB4A, member RAS oncogene family [Source:HGNC Sym... [more]
RAB4B2.248e-8054.21RAB4B, member RAS oncogene family [Source:HGNC Sym... [more]
RAB4B2.248e-8054.21RAB4B, member RAS oncogene family [Source:HGNC Sym... [more]
RAB4B-EGLN22.248e-8054.21RAB4B-EGLN2 readthrough (NMD candidate) [Source:HG... [more]
RAB148.209e-6853.22RAB14, member RAS oncogene family [Source:HGNC Sym... [more]
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BLAST of Ras-related protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab-141.227e-6547.06RAB family [Source:UniProtKB/TrEMBL;Acc:Q93874][more]
rab-141.227e-6547.06RAB family [Source:UniProtKB/TrEMBL;Acc:Q93874][more]
unc-1081.888e-5851.14pep chromosome:WBcel235:I:3822883:3826514:1 gene:W... [more]
unc-1082.255e-5851.14pep chromosome:WBcel235:I:3824947:3826514:1 gene:W... [more]
F11A5.42.897e-5050.88pep chromosome:WBcel235:V:16195679:16196290:1 gene... [more]
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BLAST of Ras-related protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rab41.299e-7761.36gene:FBgn0016701 transcript:FBtr0086829[more]
Rab41.299e-7761.36gene:FBgn0016701 transcript:FBtr0086830[more]
Rab145.821e-6853.22gene:FBgn0015791 transcript:FBtr0343678[more]
Rab145.821e-6853.22gene:FBgn0015791 transcript:FBtr0080626[more]
Rab141.118e-6753.22gene:FBgn0015791 transcript:FBtr0080627[more]
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BLAST of Ras-related protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab4a1.347e-8359.70RAB4a, member RAS oncogene family [Source:NCBI gen... [more]
rab4b3.283e-8154.21RAB4B, member RAS oncogene family [Source:NCBI gen... [more]
rab4b3.283e-8154.21RAB4B, member RAS oncogene family [Source:NCBI gen... [more]
rab144.205e-6853.80RAB14, member RAS oncogene family [Source:ZFIN;Acc... [more]
rab14l1.905e-6752.63RAB14, member RAS oncogene family, like [Source:ZF... [more]
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BLAST of Ras-related protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
map41.848e-8063.64microtubule associated protein 4 [Source:Xenbase;A... [more]
map42.983e-7462.65microtubule associated protein 4 [Source:Xenbase;A... [more]
map44.183e-6254.55microtubule associated protein 4 [Source:Xenbase;A... [more]
RAB2A2.520e-5847.72RAB2A, member RAS oncogene family [Source:NCBI gen... [more]
hus15.121e-5851.72HUS1 checkpoint clamp component [Source:Xenbase;Ac... [more]
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BLAST of Ras-related protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rab4a2.206e-8356.54RAB4A, member RAS oncogene family [Source:MGI Symb... [more]
Rab4a2.206e-8356.54RAB4A, member RAS oncogene family [Source:MGI Symb... [more]
Rab4b4.968e-8154.67RAB4B, member RAS oncogene family [Source:MGI Symb... [more]
Rab148.163e-6853.22RAB14, member RAS oncogene family [Source:MGI Symb... [more]
Rab2a3.709e-5952.27RAB2A, member RAS oncogene family [Source:MGI Symb... [more]
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BLAST of Ras-related protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P20338|RAB4A_HUMAN6.962e-8356.54Ras-related protein Rab-4A OS=Homo sapiens OX=9606... [more]
sp|Q2TBH7|RAB4A_BOVIN8.289e-8356.54Ras-related protein Rab-4A OS=Bos taurus OX=9913 G... [more]
sp|Q6PHI9|RAB4A_DANRE1.017e-8259.70Ras-related protein Rab-4A OS=Danio rerio OX=7955 ... [more]
sp|P05714|RAB4A_RAT1.150e-8256.54Ras-related protein Rab-4A OS=Rattus norvegicus OX... [more]
sp|P56371|RAB4A_MOUSE1.543e-8256.54Ras-related protein Rab-4A OS=Mus musculus OX=1009... [more]
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BLAST of Ras-related protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3Q5W33.917e-8157.48ras-related protein Rab-4A isoform X2 OS=Salmo sal... [more]
A0A553Q7X87.542e-8157.01Uncharacterized protein OS=Danionella translucida ... [more]
A0A455AMG01.203e-8065.19ras-related protein Rab-4A isoform X4 OS=Physeter ... [more]
Q53GC21.236e-8056.54RAB4A, member RAS oncogene family variant (Fragmen... [more]
A0A2Y9SBZ81.263e-8057.01ras-related protein Rab-4A isoform X2 OS=Physeter ... [more]
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BLAST of Ras-related protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab4a2.558e-8356.54RAB4A, member RAS oncogene family [Source:NCBI gen... [more]
rab4b9.875e-8254.67ras-related protein Rab-4B [Source:NCBI gene;Acc:1... [more]
rab143.564e-6853.80ras-related protein Rab-14 [Source:NCBI gene;Acc:1... [more]
ENSAMXT00000039673.11.989e-6753.22pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
rab4b6.915e-6251.37ras-related protein Rab-4B [Source:NCBI gene;Acc:1... [more]
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BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab4b1.098e-7556.78RAB4B, member RAS oncogene family [Source:NCBI gen... [more]
ENSPMAT00000002219.11.013e-6846.95pep scaffold:Pmarinus_7.0:GL483980:50:9020:-1 gene... [more]
RAB2B2.031e-6151.91RAB2B, member RAS oncogene family [Source:HGNC Sym... [more]
rab2a3.550e-6052.84RAB2A, member RAS oncogene family [Source:ZFIN;Acc... [more]
RAB2B6.092e-6052.84RAB2B, member RAS oncogene family [Source:HGNC Sym... [more]
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BLAST of Ras-related protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
YPT12.974e-5548.28Rab family GTPase; involved in the ER-to-Golgi ste... [more]
YPT312.029e-5351.57Rab family GTPase; involved in the exocytic pathwa... [more]
YPT323.876e-5246.37Rab family GTPase involved in the exocytic pathway... [more]
SEC47.532e-4845.35Rab family GTPase; essential for vesicle-mediated ... [more]
VPS211.891e-3942.33Endosomal Rab family GTPase; required for endocyti... [more]
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BLAST of Ras-related protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO430475.900e-8264.20Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO433196.781e-6853.22Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO366871.889e-5951.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO431293.112e-5451.22Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO331713.338e-5045.60Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Ras-related protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab4a4.532e-8357.01RAB4A, member RAS oncogene family [Source:NCBI gen... [more]
rab4b4.717e-8154.67ras-related protein Rab-4B [Source:NCBI gene;Acc:1... [more]
rab4b3.603e-7653.27ras-related protein Rab-4B [Source:NCBI gene;Acc:1... [more]
rab4b7.613e-7654.11ras-related protein Rab-4B [Source:NCBI gene;Acc:1... [more]
ENSORLT00000033612.11.119e-6848.36ras-related protein Rab-14 [Source:NCBI gene;Acc:1... [more]
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BLAST of Ras-related protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000044147.12.762e-153100.00SMESG000044147.1[more]
SMESG000044147.17.088e-126100.00SMESG000044147.1[more]
SMESG000044157.15.410e-7454.68SMESG000044157.1[more]
SMESG000081610.11.042e-6956.25SMESG000081610.1[more]
SMESG000024495.11.219e-6554.02SMESG000024495.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30009981 ID=SMED30009981|Name=Ras-related protein|organism=Schmidtea mediterranea sexual|type=transcript|length=850bp
TTTAATTTGCAATTTTATATCATATCAACTGAAACCAGTGAGATTATTAG
TTCAGATATTTTACAAAAAAAACTATTTTTATAAATTTATATAATAAAAT
CAAATTTCTGAAAAATGTCAGAAATATATGATCATTTATTTAAATTCTTA
TTGATTGGAAATTCTGGAGTTGGAAAATCTTGTGTTTTAAATCAATTTAT
TGAAGAGCAATTTCGTATGGACAGTACTCATACAATAGGAGTTGAATTTG
CAAGCAAGATCATTTCAATTGCAAGTAGAAAGGTGAAATTGCAGATTTGG
GATACAGCAGGCCAAGAAAGGTTCCGCTCTGTGACAAAATCTTACTATCG
GAAAGCAGTTGGTGCTTTGCTGGTGTATGATGTGAGCGACCGGGAATCAT
TTAATGGTCTCAGTAAATGGCTGATTGATGTGAAACAGCTCAGTGGTGAT
GGGATCATTGTCATTTTAGTTGGCAACAAAATTGACAGGCCCGACGAGTC
ACGGGAAGTTTCATTTGTCGAAGGAACTCAATTTGCCCAGGAGAATGAGC
TGATGTTCATTGAGACATCGGCAGTGACCGGTGAAAATGTTTCAGAGGCA
TTTATCAATGTTGCCCGACGAATTCTACACAATCTCGAAACAGTTTTAGA
TCATCCAGTTGATGATGTTAATGATTTCCGTTCCGCTGACATTCGAAGGC
CTTATTTACGCACACCGACTGAATCGTGCCGGTGTTGAAATGTCACCAAT
GAAATATTCTCGTGGCTGTGATTGGATAGAATGTATACAAGCAAATAAAT
TAGCATGACTTCTTCATTTATTCGAGTGTTTGCTGTGCGTTTTGATTGGA
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protein sequence of SMED30009981-orf-1

>SMED30009981-orf-1 ID=SMED30009981-orf-1|Name=SMED30009981-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=208bp
MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKII
SIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLS
KWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIE
TSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRT
PTESCRC*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003924GTPase activity
GO:0005525GTP binding
GO:0000166nucleotide binding
Vocabulary: biological process
TermDefinition
GO:0032482Rab protein signal transduction
GO:0007264small GTPase mediated signal transduction
GO:0001944vasculature development
GO:0006810transport
GO:0015031protein transport
GO:0030100regulation of endocytosis
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR005225Small_GTP-bd_dom
IPR001806Small_GTPase
IPR027417P-loop_NTPase
Vocabulary: cellular component
TermDefinition
GO:0005768endosome
GO:0005886plasma membrane
GO:0016020membrane
GO:0032593insulin-responsive compartment
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR00449RASTRNSFRMNGcoord: 50..72
score: 51.1
coord: 112..125
score: 45.61
coord: 32..48
score: 30.95
coord: 148..170
score: 42.43
coord: 9..30
score: 46.13
NoneNo IPR availableSMARTSM00175rab_sub_5coord: 9..173
e-value: 1.1E-89
score: 313.9
NoneNo IPR availableSMARTSM00174rho_sub_3coord: 11..173
e-value: 9.6E-9
score: -6.7
NoneNo IPR availableSMARTSM00177arf_sub_2coord: 1..174
e-value: 0.0056
score: -1.3
NoneNo IPR availableSMARTSM00173ras_sub_4coord: 6..173
e-value: 3.9E-24
score: 96.2
NoneNo IPR availableSMARTSM00176ran_sub_2coord: 14..205
e-value: 4.9E-5
score: 22.5
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 2..183
e-value: 2.3E-62
score: 211.9
NoneNo IPR availablePANTHERPTHR24073FAMILY NOT NAMEDcoord: 4..181
NoneNo IPR availablePANTHERPTHR24073:SF387RAS-RELATED PROTEIN RAB-4Bcoord: 4..181
NoneNo IPR availablePROSITEPS51419RABcoord: 4..205
score: 33.128
IPR001806Small GTPasePFAMPF00071Rascoord: 10..171
e-value: 4.8E-56
score: 188.8
IPR005225Small GTP-binding protein domainTIGRFAMTIGR00231TIGR00231coord: 9..165
e-value: 1.7E-29
score: 100.6
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 5..198