PBPe domain-containing protein

Overview


Name	PBPe domain-containing protein
Smed ID	SMED30009951
Length (bp)	621

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30009951

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30009951	h1SMcG0002646	SmedASXL_001063	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
head region	SMED30009951	h1SMcG0015991	SmedASXL_002312	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
reproductive organ	SMED30009951	h1SMcG0002646	Contig52440	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30009951	h1SMcG0002646	Contig52440	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of PBPe domain-containing protein vs. Ensembl Human
Match: GRID1 (glutamate ionotropic receptor delta type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4575])

HSP 1 Score: 60.4622 bits (145), Expect = 3.545e-10
Identity = 45/177 (25.42%), Postives = 83/177 (46.89%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESR--IWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            G   ++L  L+  + FK  +Y+A D  +G ++ N+S   + G IG++ + ++    S  T   +R+  VDFS  +MD S    +   KPE +  I+ +F P  +  W  I   + +  V+ ++ +    + A +   P        L    W + G+F+ QG +    SM+ R V+ 
Sbjct:  465 GFSIDVLDALAKALGFKYEIYQAPDGRYGHQLHNTS---WNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYS--VGILIKKPEEKISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVRAQSAAQPRPSASAT-LHSAIWIVYGAFVQQGGESSVNSMAMRIVMG 635

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Human
Match: GRID1 (glutamate ionotropic receptor delta type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4575])

HSP 1 Score: 60.077 bits (144), Expect = 3.984e-10
Identity = 45/177 (25.42%), Postives = 83/177 (46.89%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESR--IWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            G   ++L  L+  + FK  +Y+A D  +G ++ N+S   + G IG++ + ++    S  T   +R+  VDFS  +MD S    +   KPE +  I+ +F P  +  W  I   + +  V+ ++ +    + A +   P        L    W + G+F+ QG +    SM+ R V+ 
Sbjct:  465 GFSIDVLDALAKALGFKYEIYQAPDGRYGHQLHNTS---WNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYS--VGILIKKPEEKISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVRAQSAAQPRPSASAT-LHSAIWIVYGAFVQQGGESSVNSMAMRIVMG 635

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Human
Match: GRIK5 (glutamate ionotropic receptor kainate type subunit 5 [Source:HGNC Symbol;Acc:HGNC:4583])

HSP 1 Score: 53.1434 bits (126), Expect = 1.077e-7
Identity = 47/183 (25.68%), Postives = 82/183 (44.81%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIF-RPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLN-----LPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            E+  G   +ML+ L+  ++F+  L   ED L+GA   N S   +TG +G++ N K+    + FT   +R+  +DFS  FM        +        +  F  P     W  ++L  +  S + +L +  SP   +N +      P  + ++  L    W  +G F+ QG +  P ++S R V
Sbjct:  441 ERFEGFCVDMLRELAELLRFRYRLRLVEDGLYGAPEPNGS---WTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCV 620

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Human
Match: GRIK5 (glutamate ionotropic receptor kainate type subunit 5 [Source:HGNC Symbol;Acc:HGNC:4583])

HSP 1 Score: 52.7582 bits (125), Expect = 1.311e-7
Identity = 47/183 (25.68%), Postives = 82/183 (44.81%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIF-RPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLN-----LPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            E+  G   +ML+ L+  ++F+  L   ED L+GA      N S+TG +G++ N K+    + FT   +R+  +DFS  FM        +        +  F  P     W  ++L  +  S + +L +  SP   +N +      P  + ++  L    W  +G F+ QG +  P ++S R V
Sbjct:  441 ERFEGFCVDMLRELAELLRFRYRLRLVEDGLYGA---PEPNGSWTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCV 620

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Human
Match: GRIK5 (glutamate ionotropic receptor kainate type subunit 5 [Source:HGNC Symbol;Acc:HGNC:4583])

HSP 1 Score: 52.7582 bits (125), Expect = 1.311e-7
Identity = 47/183 (25.68%), Postives = 82/183 (44.81%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIF-RPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLN-----LPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            E+  G   +ML+ L+  ++F+  L   ED L+GA      N S+TG +G++ N K+    + FT   +R+  +DFS  FM        +        +  F  P     W  ++L  +  S + +L +  SP   +N +      P  + ++  L    W  +G F+ QG +  P ++S R V
Sbjct:  441 ERFEGFCVDMLRELAELLRFRYRLRLVEDGLYGA---PEPNGSWTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCV 620

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BLAST of PBPe domain-containing protein vs. Ensembl Celegans
Match: glr-1 (Glutamate receptor 1 [Source:UniProtKB/Swiss-Prot;Acc:P34299])

HSP 1 Score: 61.2326 bits (147), Expect = 6.700e-11
Identity = 50/181 (27.62%), Postives = 88/181 (48.62%), Query Frame = 1

Query:   82 KTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIF---RPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLP----FSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSAR 603
            K  G   ++LK+L+ K++     +  E KL        ++ S+ G IG++ +G++    +  T N +R+  VDFS  FM  +   S+   KP+ + + +F   +PL    W  II   +  SV+ +L S +SP   W +       F+I ++  +    W  + +F+ QG D  P S+S R
Sbjct:  491 KFEGFCIDLLKLLADKIE----EFNYEIKLGTKAGSKQADGSWDGMIGELLSGRAHAVVASLTINQERERVVDFSKPFM--TTGISIMIKKPDKQEFSVFSFMQPLSTEIWMYIIFAYIGVSVVIFLVSRFSPYE-WRVEETSRGGFTISNDFSVYNCLWFTLAAFMQQGTDILPRSISGR 664

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BLAST of PBPe domain-containing protein vs. Ensembl Celegans
Match: glr-7 (GLutamate Receptor family (AMPA) [Source:UniProtKB/TrEMBL;Acc:Q18591])

HSP 1 Score: 52.7582 bits (125), Expect = 4.664e-8
Identity = 44/179 (24.58%), Postives = 80/179 (44.69%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASL-QFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIR---LREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            G   +++ ++ V++ F   +YE ED  +G    N +   + G IG + +G +    +  +   +R+  VDF+V + D      L +    E  ++   + L W  W  I+   +  S++ ++F  +SP S  N    +    E R   L+E  W  + S   QG    P ++S R V A
Sbjct:  183 GYCIDLINMIQVEVNFTYTIYEVEDGSFGTMDDNGN---WNGLIGALVSGSADIALAPLSVMAERENDVDFTVPYYDLVGTTILMKKADVEYSLFKFMKVLEWPVWLCIVAAYLFTSILLWIFDRFSPYSFTNNKERYQNDIEKRQFSLKECLWFCMTSLTPQGGGEAPKNISGRLVAA 358

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Celegans
Match: glr-7 (GLutamate Receptor family (AMPA) [Source:UniProtKB/TrEMBL;Acc:Q18591])

HSP 1 Score: 52.7582 bits (125), Expect = 5.586e-8
Identity = 44/179 (24.58%), Postives = 80/179 (44.69%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASL-QFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIR---LREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            G   +++ ++ V++ F   +YE ED  +G    N +   + G IG + +G +    +  +   +R+  VDF+V + D      L +    E  ++   + L W  W  I+   +  S++ ++F  +SP S  N    +    E R   L+E  W  + S   QG    P ++S R V A
Sbjct:  378 GYCIDLINMIQVEVNFTYTIYEVEDGSFGTMDDNGN---WNGLIGALVSGSADIALAPLSVMAERENDVDFTVPYYDLVGTTILMKKADVEYSLFKFMKVLEWPVWLCIVAAYLFTSILLWIFDRFSPYSFTNNKERYQNDIEKRQFSLKECLWFCMTSLTPQGGGEAPKNISGRLVAA 553

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Celegans
Match: glr-7 (GLutamate Receptor family (AMPA) [Source:UniProtKB/TrEMBL;Acc:Q18591])

HSP 1 Score: 52.373 bits (124), Expect = 6.270e-8
Identity = 44/179 (24.58%), Postives = 80/179 (44.69%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASL-QFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIR---LREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            G   +++ ++ V++ F   +YE ED  +G    N +   + G IG + +G +    +  +   +R+  VDF+V + D      L +    E  ++   + L W  W  I+   +  S++ ++F  +SP S  N    +    E R   L+E  W  + S   QG    P ++S R V A
Sbjct:  397 GYCIDLINMIQVEVNFTYTIYEVEDGSFGTMDDNGN---WNGLIGALVSGSADIALAPLSVMAERENDVDFTVPYYDLVGTTILMKKADVEYSLFKFMKVLEWPVWLCIVAAYLFTSILLWIFDRFSPYSFTNNKERYQNDIEKRQFSLKECLWFCMTSLTPQGGGEAPKNISGRLVAA 572

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Celegans
Match: glr-2 (Glutamate receptor 2 [Source:UniProtKB/Swiss-Prot;Acc:Q10914])

HSP 1 Score: 51.6026 bits (122), Expect = 1.199e-7
Identity = 45/177 (25.42%), Postives = 83/177 (46.89%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQ-FKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIF---RPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWN--LNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSAR 603
            G   ++L +L+  +  F+  ++ ++   +G+R    ++ S+ G IG + N  +    +  T   +R+  VDFS  FM  +   S+   KPE + ++IF    PL  T W   +      S+  +L S++SP           F++ +E  L    W  + +F+ QG D  P ++S R
Sbjct:  451 GYCIDLLNLLAKNITGFEYDVFISDGNKYGSR---QADGSWDGMIGYLLNETADVAVAPLTITQERERAVDFSKPFM--TTGISIMIKKPEKQEFNIFSFMEPLGMTIWIFTLSSYFGVSLTIFLVSWFSPYEKRIEFKRGEFTVTNEFTLYNSLWFTLAAFMQQGTDILPRAVSGR 622

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BLAST of PBPe domain-containing protein vs. Ensembl Fly
Match: Ekar (gene:FBgn0039916 transcript:FBtr0089102)

HSP 1 Score: 58.5362 bits (140), Expect = 7.055e-10
Identity = 47/184 (25.54%), Postives = 84/184 (45.65%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPES---RIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNL----PFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            E+  G   ++L+ +S ++ F  +L    D+ +GA  K+     + G +  +   K+       T  Y R+  +DF+  FM+     S+ F  P S   R++    PL    W  +++   + S+  Y+    SP+    +N       SI ++  L + FW  IG+F+ Q  D YP +MS R +
Sbjct:  428 ERFYGFCVDILETISREVGFDYILDLVPDRKYGA--KDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLG--ISILFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGNQFSLTDSFWFTIGTFMQQSPDIYPRAMSTRII 607

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BLAST of PBPe domain-containing protein vs. Ensembl Fly
Match: Ekar (gene:FBgn0039916 transcript:FBtr0110906)

HSP 1 Score: 58.5362 bits (140), Expect = 7.342e-10
Identity = 47/184 (25.54%), Postives = 84/184 (45.65%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPES---RIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNL----PFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            E+  G   ++L+ +S ++ F  +L    D+ +GA  K+     + G +  +   K+       T  Y R+  +DF+  FM+     S+ F  P S   R++    PL    W  +++   + S+  Y+    SP+    +N       SI ++  L + FW  IG+F+ Q  D YP +MS R +
Sbjct:  428 ERFYGFCVDILETISREVGFDYILDLVPDRKYGA--KDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLG--ISILFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGNQFSLTDSFWFTIGTFMQQSPDIYPRAMSTRII 607

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Fly
Match: Ekar (gene:FBgn0039916 transcript:FBtr0344874)

HSP 1 Score: 54.299 bits (129), Expect = 1.753e-8
Identity = 48/184 (26.09%), Postives = 85/184 (46.20%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPES---RIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNL----PFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            E+  G   ++L+ +S ++ F  +L    D+ +GA  K+     + G +  +     L   S+ T  Y R+  +DF+  FM+     S+ F  P S   R++    PL    W  +++   + S+  Y+    SP+    +N       SI ++  L + FW  IG+F+ Q  D YP +MS R +
Sbjct:  428 ERFYGFCVDILETISREVGFDYILDLVPDRKYGA--KDPETGEWNGMVAQLMKYADLAVGSM-TITYARESVIDFTKPFMNLG--ISILFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGNQFSLTDSFWFTIGTFMQQSPDIYPRAMSTRII 606

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Fly
Match: CG11155 (gene:FBgn0039927 transcript:FBtr0333701)

HSP 1 Score: 50.447 bits (119), Expect = 3.362e-7
Identity = 41/180 (22.78%), Postives = 81/180 (45.00%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPES---RIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIID----EIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            G   ++LK ++ ++ F+  +    D ++G  I  ++  S+ G + ++   ++    +  T NY R+  +DF+  FM+      + F  P S   R++    PL    W  ++   ++ S   ++ + +SP    N +  +   D    +  +   FW I G+FL QG    P + S R V
Sbjct:  454 GFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETN--SWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLG--IGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKETDIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIV 629

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Fly
Match: CG11155 (gene:FBgn0039927 transcript:FBtr0089195)

HSP 1 Score: 50.447 bits (119), Expect = 3.362e-7
Identity = 41/180 (22.78%), Postives = 81/180 (45.00%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPES---RIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIID----EIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            G   ++LK ++ ++ F+  +    D ++G  I  ++  S+ G + ++   ++    +  T NY R+  +DF+  FM+      + F  P S   R++    PL    W  ++   ++ S   ++ + +SP    N +  +   D    +  +   FW I G+FL QG    P + S R V
Sbjct:  454 GFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETN--SWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLG--IGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKETDIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIV 629

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Zebrafish
Match: grid1b (glutamate receptor, ionotropic, delta 1b [Source:ZFIN;Acc:ZDB-GENE-121214-84])

HSP 1 Score: 56.6102 bits (135), Expect = 3.685e-9
Identity = 48/184 (26.09%), Postives = 88/184 (47.83%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESR--IWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWN---LNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            ++  G   ++L+ L+  + FK  +Y+  D  +G+++   SN S+ G IG++ N ++    S  T   +R+  VDFS  +MD S    +   KPE +  I+ +F P     W  I   + +  V+ +L +    L + N    +   S+ +   L    W + G+F+ QG D    S++ R V+ 
Sbjct:  462 KRYKGFSIDVLEALAKILGFKYDIYQVADSKYGSQL---SNGSWNGMIGELINKRADLAVSAITITPERENVVDFSKRYMDYS--VGILHRKPEEKINIFSLFAPFDLAVWACIAAAIPVVGVLIFLLTRMQMLRSQNPPGAHHASSMSNS--LHSAIWIVYGAFVQQGGDSVVGSVALRIVMG 638

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Zebrafish
Match: gria2a (glutamate receptor, ionotropic, AMPA 2a [Source:ZFIN;Acc:ZDB-GENE-020125-3])

HSP 1 Score: 54.6842 bits (130), Expect = 1.733e-8
Identity = 48/187 (25.67%), Postives = 81/187 (43.32%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESR---IWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNL-------PFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            E+  G   ++   ++    FK  L    D  +GAR  ++    + G +G++  GK+    +  T    R+  +DFS  FM  S   S+   KP+     ++    PL +  W  I+   +  SV+ +L S +SP   W+          P    +E  +    W  +G+F+ QG D  P S+S R V
Sbjct:  433 ERYEGYCVDLAAEIAKHCGFKYQLRIVADGKYGAR--DAETKIWNGMVGELVYGKADIAVAPLTITLVREEVIDFSKPFM--SLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE-WHTEEFEDGQLGPSESTNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIV 614

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Zebrafish
Match: gria2a (glutamate receptor, ionotropic, AMPA 2a [Source:ZFIN;Acc:ZDB-GENE-020125-3])

HSP 1 Score: 54.6842 bits (130), Expect = 1.896e-8
Identity = 48/187 (25.67%), Postives = 81/187 (43.32%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESR---IWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNL-------PFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            E+  G   ++   ++    FK  L    D  +GAR  ++    + G +G++  GK+    +  T    R+  +DFS  FM  S   S+   KP+     ++    PL +  W  I+   +  SV+ +L S +SP   W+          P    +E  +    W  +G+F+ QG D  P S+S R V
Sbjct:  437 ERYEGYCVDLAAEIAKHCGFKYQLRIVADGKYGAR--DAETKIWNGMVGELVYGKADIAVAPLTITLVREEVIDFSKPFM--SLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE-WHTEEFEDGQLGPSESTNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIV 618

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Zebrafish
Match: gria2a (glutamate receptor, ionotropic, AMPA 2a [Source:ZFIN;Acc:ZDB-GENE-020125-3])

HSP 1 Score: 54.6842 bits (130), Expect = 1.896e-8
Identity = 48/187 (25.67%), Postives = 81/187 (43.32%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESR---IWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNL-------PFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            E+  G   ++   ++    FK  L    D  +GAR  ++    + G +G++  GK+    +  T    R+  +DFS  FM  S   S+   KP+     ++    PL +  W  I+   +  SV+ +L S +SP   W+          P    +E  +    W  +G+F+ QG D  P S+S R V
Sbjct:  437 ERYEGYCVDLAAEIAKHCGFKYQLRIVADGKYGAR--DAETKIWNGMVGELVYGKADIAVAPLTITLVREEVIDFSKPFM--SLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE-WHTEEFEDGQLGPSESTNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIV 618

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Zebrafish
Match: grid1b (glutamate receptor, ionotropic, delta 1b [Source:ZFIN;Acc:ZDB-GENE-121214-84])

HSP 1 Score: 53.1434 bits (126), Expect = 2.607e-8
Identity = 44/169 (26.04%), Postives = 81/169 (47.93%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESR--IWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWN---LNLPFSIIDEIRLREHFWNIIGSFLMQG 570
            ++  G   ++L+ L+  + FK  +Y+  D  +G+++   SN S+ G IG++ N ++    S  T   +R+  VDFS  +MD S    +   KPE +  I+ +F P     W  I   + +  V+ +L +    L + N    +   S+ +   L    W + G+F+ QG
Sbjct:   28 KRYKGFSIDVLEALAKILGFKYDIYQVADSKYGSQL---SNGSWNGMIGELINKRADLAVSAITITPERENVVDFSKRYMDYS--VGILHRKPEEKINIFSLFAPFDLAVWACIAAAIPVVGVLIFLLTRMQMLRSQNPPGAHHASSMSNS--LHSAIWIVYGAFVQQG 189

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Xenopus
Match: ogfr (opioid growth factor receptor [Source:Xenbase;Acc:XB-GENE-997410])

HSP 1 Score: 55.0694 bits (131), Expect = 2.192e-8
Identity = 48/184 (26.09%), Postives = 83/184 (45.11%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDE--SNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWN----LNLPFSIID-EIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            ++  G   EML  L+  ++F   +   ED L+GA   N S   +TG +G++ N K+    + FT   +R+  +DFS  FM    S    +Q  + +   +    P     W  ++L  +  S + +L +  SP   +N    L     I++ +  L    W  +G F+ QG +  P ++S R V
Sbjct:  391 DQYEGFCAEMLMELAALLRFNYKIKLVEDGLYGAPEPNGS---WTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVQMGR-KPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRERHHILENQYTLGNSLWFPVGGFMQQGSEVMPRALSTRCV 570

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Xenopus
Match: ogfr (opioid growth factor receptor [Source:Xenbase;Acc:XB-GENE-997410])

HSP 1 Score: 53.9138 bits (128), Expect = 5.160e-8
Identity = 48/184 (26.09%), Postives = 83/184 (45.11%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDE--SNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWN----LNLPFSIID-EIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            ++  G   EML  L+  ++F   +   ED L+GA   N S   +TG +G++ N K+    + FT   +R+  +DFS  FM    S    +Q  + +   +    P     W  ++L  +  S + +L +  SP   +N    L     I++ +  L    W  +G F+ QG +  P ++S R V
Sbjct:  156 DQYEGFCAEMLMELAALLRFNYKIKLVEDGLYGAPEPNGS---WTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVQMGR-KPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRERHHILENQYTLGNSLWFPVGGFMQQGSEVMPRALSTRCV 335

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Xenopus
Match: ogfr (opioid growth factor receptor [Source:Xenbase;Acc:XB-GENE-997410])

HSP 1 Score: 51.9878 bits (123), Expect = 1.903e-7
Identity = 48/180 (26.67%), Postives = 80/180 (44.44%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDE--SNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWN----LNLPFSIID-EIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            G   EML  L+  ++F   +   ED L+GA   N S   +TG +G++ N K+    + FT   +R+  +DFS  FM    S    +Q  +     +    P     W  ++L  +  S + +L +  SP   +N    L     I++ +  L    W  +G F+ QG +  P ++S R V
Sbjct:  439 GFCAEMLMELAALLRFNYKIKLVEDGLYGAPEPNGS---WTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVQMGRKPG-YFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRERHHILENQYTLGNSLWFPVGGFMQQGSEVMPRALSTRCV 614

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Xenopus
Match: ogfr (opioid growth factor receptor [Source:Xenbase;Acc:XB-GENE-997410])

HSP 1 Score: 51.9878 bits (123), Expect = 2.210e-7
Identity = 48/180 (26.67%), Postives = 80/180 (44.44%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDE--SNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWN----LNLPFSIID-EIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            G   EML  L+  ++F   +   ED L+GA   N S   +TG +G++ N K+    + FT   +R+  +DFS  FM    S    +Q  +     +    P     W  ++L  +  S + +L +  SP   +N    L     I++ +  L    W  +G F+ QG +  P ++S R V
Sbjct:  441 GFCAEMLMELAALLRFNYKIKLVEDGLYGAPEPNGS---WTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVQMGRKPG-YFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRERHHILENQYTLGNSLWFPVGGFMQQGSEVMPRALSTRCV 616

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Xenopus
Match: ogfr (opioid growth factor receptor [Source:Xenbase;Acc:XB-GENE-997410])

HSP 1 Score: 51.9878 bits (123), Expect = 2.258e-7
Identity = 48/180 (26.67%), Postives = 80/180 (44.44%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDE--SNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWN----LNLPFSIID-EIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            G   EML  L+  ++F   +   ED L+GA   N S   +TG +G++ N K+    + FT   +R+  +DFS  FM    S    +Q  +     +    P     W  ++L  +  S + +L +  SP   +N    L     I++ +  L    W  +G F+ QG +  P ++S R V
Sbjct:  441 GFCAEMLMELAALLRFNYKIKLVEDGLYGAPEPNGS---WTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVQMGRKPG-YFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRERHHILENQYTLGNSLWFPVGGFMQQGSEVMPRALSTRCV 616

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Mouse
Match: Grid1 (glutamate receptor, ionotropic, delta 1 [Source:MGI Symbol;Acc:MGI:95812])

HSP 1 Score: 57.3806 bits (137), Expect = 2.520e-9
Identity = 43/177 (24.29%), Postives = 83/177 (46.89%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESR--IWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            G   ++L  L+  + FK  +Y+A D  +G ++ N+S   + G IG++ + ++    S  T   +R+  VDFS  +MD S    +   KPE +  I+ +F P  +  W  I   + +  V+ ++ +    + + +   P        L    W + G+F+ QG +    S++ R V+ 
Sbjct:  465 GFSIDVLDALAKALGFKYEIYQAPDGRYGHQLHNTS---WNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYS--VGILIKKPEEKISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVRSQSATQPRPSASAT-LHSAIWIVYGAFVQQGGESSVNSVAMRIVMG 635

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Mouse
Match: Grik5 (glutamate receptor, ionotropic, kainate 5 (gamma 2) [Source:MGI Symbol;Acc:MGI:95818])

HSP 1 Score: 52.7582 bits (125), Expect = 9.168e-8
Identity = 47/183 (25.68%), Postives = 82/183 (44.81%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIF-RPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLN-----LPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            E+  G   +ML+ L+  ++F+  L   ED L+GA   N S   +TG +G++ N K+    + FT   +R+  +DFS  FM        +        +  F  P     W  ++L  +  S + +L +  SP   +N +      P  + ++  L    W  +G F+ QG +  P ++S R V
Sbjct:  441 ERFEGFCVDMLRELAELLRFRYRLRLVEDGLYGAPEPNGS---WTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCV 620

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Mouse
Match: Gria4 (glutamate receptor, ionotropic, AMPA4 (alpha 4) [Source:MGI Symbol;Acc:MGI:95811])

HSP 1 Score: 50.447 bits (119), Expect = 5.962e-7
Identity = 44/160 (27.50%), Postives = 71/160 (44.38%), Query Frame = 1

Query:  163 DKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFR---PLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIID--------EIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            D  +GAR  ++    + G +G++  GK+    +  T    R+  +DFS  FM  S   S+   KP+     +F    PL +  W  I+   +  SV+ +L S +SP   W+   P    +        E  +    W  +G+F+ QG D  P S+S R V
Sbjct:  469 DGKYGAR--DADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFM--SLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE-WHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIV 623

[Close]

Query:  163 DKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFR---PLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIID--------EIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            D  +GAR  ++    + G +G++  GK+    +  T    R+  +DFS  FM  S   S+   KP+     +F    PL +  W  I+   +  SV+ +L S +SP   W+   P    +        E  +    W  +G+F+ QG D  P S+S R V
Sbjct:  469 DGKYGAR--DADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFM--SLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE-WHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIV 623

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Mouse
Match: Gria4 (glutamate receptor, ionotropic, AMPA4 (alpha 4) [Source:MGI Symbol;Acc:MGI:95811])

HSP 1 Score: 50.0618 bits (118), Expect = 6.304e-7
Identity = 44/160 (27.50%), Postives = 71/160 (44.38%), Query Frame = 1

Query:  163 DKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFR---PLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIID--------EIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            D  +GAR  ++    + G +G++  GK+    +  T    R+  +DFS  FM  S   S+   KP+     +F    PL +  W  I+   +  SV+ +L S +SP   W+   P    +        E  +    W  +G+F+ QG D  P S+S R V
Sbjct:  469 DGKYGAR--DADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFM--SLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE-WHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIV 623

[Close]

BLAST of PBPe domain-containing protein vs. UniProt/SwissProt
Match: sp|P26591|GLRK_LYMST (Glutamate receptor OS=Lymnaea stagnalis OX=6523 PE=2 SV=1)

HSP 1 Score: 62.3882 bits (150), Expect = 3.516e-10
Identity = 49/182 (26.92%), Postives = 87/182 (47.80%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIF---RPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFS--IIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            E   G   ++ K ++ K+ F  ++   +D  +G+ +   SN ++ G +G++   ++    + FT   DR   +DF+  FM  S   S+   +P+    H F    PL    W  I+   +  SV+ +L S +SP + W+L+      I ++  +    W  +G+F+ QG D  P SMS R V
Sbjct:  454 EPVEGFCIDLTKAVAEKVGFDFVIQFVKDGSYGSVL---SNGTWDGIVGELIRHEADMAIAPFTITADRSRVIDFTKPFM--SLGISIMIKRPQPAGKHFFSFMEPLSSEIWMCIVFAYIGVSVVLFLVSRFSP-NEWHLSEAHHSYIANDFSISNSLWFSLGAFMQQGCDISPRSMSGRIV 629

[Close]

BLAST of PBPe domain-containing protein vs. UniProt/SwissProt
Match: sp|P34299|GLR1_CAEEL (Glutamate receptor 1 OS=Caenorhabditis elegans OX=6239 GN=glr-1 PE=1 SV=2)

HSP 1 Score: 61.2326 bits (147), Expect = 8.522e-10
Identity = 50/181 (27.62%), Postives = 88/181 (48.62%), Query Frame = 1

Query:   82 KTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIF---RPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLP----FSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSAR 603
            K  G   ++LK+L+ K++     +  E KL        ++ S+ G IG++ +G++    +  T N +R+  VDFS  FM  +   S+   KP+ + + +F   +PL    W  II   +  SV+ +L S +SP   W +       F+I ++  +    W  + +F+ QG D  P S+S R
Sbjct:  491 KFEGFCIDLLKLLADKIE----EFNYEIKLGTKAGSKQADGSWDGMIGELLSGRAHAVVASLTINQERERVVDFSKPFM--TTGISIMIKKPDKQEFSVFSFMQPLSTEIWMYIIFAYIGVSVVIFLVSRFSPYE-WRVEETSRGGFTISNDFSVYNCLWFTLAAFMQQGTDILPRSISGR 664

[Close]

BLAST of PBPe domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9ULK0|GRID1_HUMAN (Glutamate receptor ionotropic, delta-1 OS=Homo sapiens OX=9606 GN=GRID1 PE=2 SV=2)

HSP 1 Score: 60.077 bits (144), Expect = 1.913e-9
Identity = 45/177 (25.42%), Postives = 83/177 (46.89%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESR--IWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            G   ++L  L+  + FK  +Y+A D  +G ++ N+S   + G IG++ + ++    S  T   +R+  VDFS  +MD S    +   KPE +  I+ +F P  +  W  I   + +  V+ ++ +    + A +   P        L    W + G+F+ QG +    SM+ R V+ 
Sbjct:  465 GFSIDVLDALAKALGFKYEIYQAPDGRYGHQLHNTS---WNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYS--VGILIKKPEEKISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVRAQSAAQPRPSASAT-LHSAIWIVYGAFVQQGGESSVNSMAMRIVMG 635

[Close]

BLAST of PBPe domain-containing protein vs. UniProt/SwissProt
Match: sp|Q62640|GRID1_RAT (Glutamate receptor ionotropic, delta-1 OS=Rattus norvegicus OX=10116 GN=Grid1 PE=1 SV=1)

HSP 1 Score: 57.3806 bits (137), Expect = 1.682e-8
Identity = 43/177 (24.29%), Postives = 83/177 (46.89%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESR--IWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            G   ++L  L+  + FK  +Y+A D  +G ++ N+S   + G IG++ + ++    S  T   +R+  VDFS  +MD S    +   KPE +  I+ +F P  +  W  I   + +  V+ ++ +    + + +   P        L    W + G+F+ QG +    S++ R V+ 
Sbjct:  465 GFSIDVLDALAKALGFKYEIYQAPDGRYGHQLHNTS---WNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYS--VGILIKKPEEKISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVRSQSATQPRPSASAT-LHSAIWIVYGAFVQQGGESSVNSVAMRIVMG 635

[Close]

BLAST of PBPe domain-containing protein vs. UniProt/SwissProt
Match: sp|Q61627|GRID1_MOUSE (Glutamate receptor ionotropic, delta-1 OS=Mus musculus OX=10090 GN=Grid1 PE=1 SV=2)

HSP 1 Score: 57.3806 bits (137), Expect = 1.763e-8
Identity = 43/177 (24.29%), Postives = 83/177 (46.89%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESR--IWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            G   ++L  L+  + FK  +Y+A D  +G ++ N+S   + G IG++ + ++    S  T   +R+  VDFS  +MD S    +   KPE +  I+ +F P  +  W  I   + +  V+ ++ +    + + +   P        L    W + G+F+ QG +    S++ R V+ 
Sbjct:  465 GFSIDVLDALAKALGFKYEIYQAPDGRYGHQLHNTS---WNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYS--VGILIKKPEEKISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVRSQSATQPRPSASAT-LHSAIWIVYGAFVQQGGESSVNSVAMRIVMG 635

[Close]

BLAST of PBPe domain-containing protein vs. TrEMBL
Match: A0A1I8HAM9 (CCHC-type domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 144.821 bits (364), Expect = 3.454e-36
Identity = 69/190 (36.32%), Postives = 113/190 (59.47%), Query Frame = 1

Query:   49 FLENGTYLPLEKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLAF 618
            F E GT L      G++ ++L IL+ ++ F+  +   +D  WG      S   F+GC+G++  G    G S FT +  R   VDFS     E+    +    PES++W+++ P  +  W L+I+ + +++ + ++ +Y+SP +A+NL L F+  DEI L+E+ W+I+GSF+ QGQDFYP++MS R VLAF
Sbjct:  949 FREKGTVL----VGGMLKDVLDILAARLDFRYSVKVPDDGQWGGPQAGRS--YFSGCVGEVQRGIVSIGGSTFTKSTTRDGVVDFSTPLFQEAYGILVPRPPPESKLWNVYAPFKYDVWILVIIFIFVSAAVTWVLAYFSPFTAYNLRLEFAFADEIWLQEYIWSIVGSFMQQGQDFYPFAMSPRAVLAF 1132

[Close]

BLAST of PBPe domain-containing protein vs. TrEMBL
Match: A0A1I8H5G6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 137.887 bits (346), Expect = 1.724e-35
Identity = 67/171 (39.18%), Postives = 104/171 (60.82%), Query Frame = 1

Query:  106 MLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLAF 618
            +L+  S ++ F+ L  ++ D  WG+   NS+   F GC+G++  G+       FT    R   +DFSV   +ESN   L    PES++W +F P   + W  I+  L + +   ++ +Y+SP +A+NLNL F+I DE+ L+E+ W+ IGSFL QGQDFYP++MS+RT +AF
Sbjct:    5 ILEYFSTQLDFRFLTKDSTDGNWGSPEVNSTY--FNGCVGELQRGEVSVAAGPFTITAARDEVIDFSVPLFEESNAILLPRPAPESKLWRVFSPFTMSVWLSIVAALFVTTFATWVLAYFSPFTAYNLNLEFAIADEVWLQEYLWSAIGSFLQQGQDFYPFAMSSRTAMAF 173

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BLAST of PBPe domain-containing protein vs. TrEMBL
Match: A0A1I8J1L9 (PBPe domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 137.502 bits (345), Expect = 3.496e-35
Identity = 67/171 (39.18%), Postives = 104/171 (60.82%), Query Frame = 1

Query:  106 MLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLAF 618
            +L+  S ++ F+ L  ++ D  WG+   NS+   F GC+G++  G+       FT    R   +DFSV   +ESN   L    PES++W +F P   + W  I+  L + +   ++ +Y+SP +A+NLNL F+I DE+ L+E+ W+ IGSFL QGQDFYP++MS+RT +AF
Sbjct:    5 ILEYFSTQLDFRFLTKDSTDGNWGSPEVNSTY--FNGCVGELQRGEVSVAAGPFTITAARDEVIDFSVPLFEESNAILLPRPAPESKLWRVFSPFTMSVWLSIVAALFVTTFATWVLAYFSPFTAYNLNLEFAIADEVWLQEYLWSAIGSFLQQGQDFYPFAMSSRTAMAF 173

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BLAST of PBPe domain-containing protein vs. TrEMBL
Match: A0A267FSX5 (PBPe domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017883g2 PE=4 SV=1)

HSP 1 Score: 139.428 bits (350), Expect = 7.412e-35
Identity = 67/176 (38.07%), Postives = 108/176 (61.36%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLAF 618
            G++ ++L IL+ ++ F+  +   +D  WG      S   F+GC+G++  G    G S FT    R   VDFS     E+N   +    PES++W+++ P  +  W L+I+ + + + + ++ +Y+SP SA+NL L F+I DEI L+E+ W+I+GSF+ QGQDFYP++MS R VLAF
Sbjct:  183 GMLKDVLDILAARLDFRYSVKVPDDGQWGGPQAGKSY--FSGCVGEVQRGIVSIGGSTFTKTAIRDSVVDFSTPLFQEANGILVPRPPPESKLWNVYAPFKYDVWILVIIFIFVCAAVTWVLAYFSPFSAYNLRLEFAIADEIWLQEYIWSIVGSFMQQGQDFYPFAMSPRAVLAF 356

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BLAST of PBPe domain-containing protein vs. TrEMBL
Match: A0A267H134 (PBPe domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017883g1 PE=3 SV=1)

HSP 1 Score: 138.658 bits (348), Expect = 3.782e-34
Identity = 66/176 (37.50%), Postives = 108/176 (61.36%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLAF 618
            G++ ++L IL+ ++ F+  +   +D  WG      S   F+GC+G++  G    G S FT    R   VDFS     E+N   +    PES++W+++ P  +  W L+I+ + + + + ++ +Y+SP +A+NL L F+I DEI L+E+ W+I+GSF+ QGQDFYP++MS R VLAF
Sbjct:  381 GMLKDVLDILAARLDFRYSVKVPDDGQWGGPQAGKS--YFSGCVGEVQRGIVSIGGSTFTKTAIRDSVVDFSTPLFQEANGILVPRPPPESKLWNVYAPFKYDVWILVIIFIFVCAAVTWVLAYFSPFTAYNLRLEFAIADEIWLQEYIWSIVGSFMQQGQDFYPFAMSPRAVLAF 554

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Cavefish
Match: GRID1 (glutamate ionotropic receptor delta type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4575])

HSP 1 Score: 62.3882 bits (150), Expect = 3.278e-11
Identity = 50/182 (27.47%), Postives = 85/182 (46.70%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESR--IWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPF-SIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            +K  G   ++L  L+  + FK  +Y+  D  +G+++   SN S+ G IG++ N ++    S  T   +R+  VDFS  +MD S    +   KPE +  I+ +F P     W  I   + +  V+ +L +    L + N   P  S      L    W + G+F+ QG D    S++ R V+ 
Sbjct:  411 KKYKGFSIDVLDALAKMLGFKYDIYQVADSKYGSQL---SNGSWNGMIGELINKRADLAVSAITITPERENVVDFSKRYMDYS--VGILMRKPEEKINIFSLFAPFDLAVWACIAAAIPVVGVLIFLLTRMQSLRSQNPPGPHQSPSMSSTLHSAIWIVYGAFVQQGGDSVVGSVALRIVMG 587

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Cavefish
Match: GRID1 (glutamate ionotropic receptor delta type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4575])

HSP 1 Score: 62.3882 bits (150), Expect = 3.844e-11
Identity = 50/182 (27.47%), Postives = 85/182 (46.70%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESR--IWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPF-SIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            +K  G   ++L  L+  + FK  +Y+  D  +G+++   SN S+ G IG++ N ++    S  T   +R+  VDFS  +MD S    +   KPE +  I+ +F P     W  I   + +  V+ +L +    L + N   P  S      L    W + G+F+ QG D    S++ R V+ 
Sbjct:  380 KKYKGFSIDVLDALAKMLGFKYDIYQVADSKYGSQL---SNGSWNGMIGELINKRADLAVSAITITPERENVVDFSKRYMDYS--VGILMRKPEEKINIFSLFAPFDLAVWACIAAAIPVVGVLIFLLTRMQSLRSQNPPGPHQSPSMSSTLHSAIWIVYGAFVQQGGDSVVGSVALRIVMG 556

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Cavefish
Match: grin3bb (glutamate receptor, ionotropic, N-methyl-D-aspartate 3Bb [Source:ZFIN;Acc:ZDB-GENE-131122-77])

HSP 1 Score: 51.9878 bits (123), Expect = 1.194e-7
Identity = 40/142 (28.17%), Postives = 65/142 (45.77%), Query Frame = 1

Query:   58 NGTYLPLEKTT---GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPL 474
            N T+LPL+ +    G   ++L+ LS  M F+  LY   D  +GA         +TG +GD+ NG +    + F+ N  R   +DF+  F   S    ++     + I     PL W+ W  I + L I ++   L+ + SP 
Sbjct:  416 NNTFLPLDYSKCCYGYCIDLLEKLSEDMDFEFDLYIVGDGKYGAW----KGGRWTGLVGDLLNGVADMAVTSFSINSARSKVMDFTSPFFSTSLGILVRSKDTAAPIGAFMWPLHWSMWVGIFVALHITALFLTLYEWKSPF 553

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Cavefish
Match: grin3bb (glutamate receptor, ionotropic, N-methyl-D-aspartate 3Bb [Source:ZFIN;Acc:ZDB-GENE-131122-77])

HSP 1 Score: 51.9878 bits (123), Expect = 1.333e-7
Identity = 40/142 (28.17%), Postives = 65/142 (45.77%), Query Frame = 1

Query:   58 NGTYLPLEKTT---GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPL 474
            N T+LPL+ +    G   ++L+ LS  M F+  LY   D  +GA         +TG +GD+ NG +    + F+ N  R   +DF+  F   S    ++     + I     PL W+ W  I + L I ++   L+ + SP 
Sbjct:  416 NNTFLPLDYSKCCYGYCIDLLEKLSEDMDFEFDLYIVGDGKYGAW----KGGRWTGLVGDLLNGVADMAVTSFSINSARSKVMDFTSPFFSTSLGILVRSKDTAAPIGAFMWPLHWSMWVGIFVALHITALFLTLYEWKSPF 553

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Cavefish
Match: grik5 (glutamate ionotropic receptor kainate type subunit 5 [Source:NCBI gene;Acc:103024859])

HSP 1 Score: 51.9878 bits (123), Expect = 1.387e-7
Identity = 49/184 (26.63%), Postives = 79/184 (42.93%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFF---KPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIR--------LREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            G   +MLK LS  ++F   +   +D L+GA   N S   +TG +G++ N K+    + FT   +R+  +DFS  FM        +     KP    +    P     W  ++L  +  S + +L +  SP   +N   P   + E R        L    W  +G F+ QG +  P ++S R V
Sbjct:  459 GFCVDMLKELSDILKFTFRIKLVDDGLYGAPEPNGS---WTGMVGELINRKADLAVAAFTITSEREKVIDFSKPFMTLGISILYRVHIGRKPG--YFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYN---PHPCLRERRDMLENQYTLGNSLWFPVGGFMQQGSEIMPKALSTRCV 634

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BLAST of PBPe domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010716.1 (pep scaffold:Pmarinus_7.0:GL476465:413535:454465:1 gene:ENSPMAG00000009705.1 transcript:ENSPMAT00000010716.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 46.9802 bits (110), Expect = 1.148e-6
Identity = 34/129 (26.36%), Postives = 60/129 (46.51%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTWTLI-ILCLVINSVIGYLFSYYSPL 474
            G   ++LK LS  ++F   LY   +   G++I    N  + G IG++ N ++       T N +R   VDFSV F++      +              P     W ++ ILCL+++ +  ++F Y+SP+
Sbjct:  398 GFCIDILKKLSKTVKFTYDLYLVTNGKHGSKI----NGVWNGMIGEVVNMRAHMAVGSLTINEERSEVVDFSVPFVETGISVMVPRSNGTVSPSAFLEPFSADVWVMMFILCLLVSGIAVFIFEYFSPV 522

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BLAST of PBPe domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000889.1 (pep scaffold:Pmarinus_7.0:GL476542:184998:205948:1 gene:ENSPMAG00000000813.1 transcript:ENSPMAT00000000889.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 44.669 bits (104), Expect = 3.794e-6
Identity = 35/136 (25.74%), Postives = 62/136 (45.59%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTWTLI-ILCLVINSVIGYLFSYYSPLSAWNLNL 495
            G   ++L+ LS  ++F   LY   +   G +I+   N    G +G++   ++       T N +R   VDFSV F++      +              P     W ++ ILCL+++++  +LF Y SP+  +N NL
Sbjct:   89 GFCIDILRKLSTTVRFTYDLYLVVNGKHGKKIQGVWN----GMVGEVEQKRAHMAVGSLTINEERSQVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSAAVWVMMFILCLMLSAIAVWLFEYLSPV-GFNRNL 219

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Nematostella
Match: EDO30203 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1G4])

HSP 1 Score: 47.7506 bits (112), Expect = 1.326e-6
Identity = 44/190 (23.16%), Postives = 81/190 (42.63%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKP----ESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLP----------FSIIDEIRLREHFWNIIGSFLMQGQD-FYPYSMSARTVLA 615
            G   E+L+ LS  ++FK  +Y   D  +GA  ++     + G + ++ NG++    +  T + +R+  +DF+  +MD          KP    E   + I RP  +  W  I   ++I     +LFS +SP   +   +             + D + L    W+ +  ++ Q  D  +P S S R  +A
Sbjct:  475 GYCIELLRKLSEMLRFKFEVYLVPDNNFGA--QDPVTKEWNGVVREVLNGRADLAVTSLTISPERQKVIDFTQPYMD---LGLTVLIKPDPTEEKNPFAILRPFRYDLWMAIGGTMIIVGFFLWLFSTFSPFGFYGRCVQKCHTKIEPRYLKLHDTLSLVRALWSTVVYYVGQSSDHLHPVSSSGRITVA 659

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Nematostella
Match: EDO35545 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SL56])

HSP 1 Score: 47.3654 bits (111), Expect = 1.602e-6
Identity = 43/180 (23.89%), Postives = 77/180 (42.78%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGA--RIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQG-QDFYPYSMSARTV 609
            +  +G   ++L  L  K+ F   +  +ED  +G+  R+  S    + G +G++  GK+    +  T N +R   ++FS  F  +     ++  +  + +    RP     W L++L + I +VI YL   +SP   + L         + L    W   G  L  G  +  P S SAR +
Sbjct:  437 DTDSGFCMDLLIRLGEKVNFTYSVSLSEDGSYGSLRRVNGSDTKQWNGMVGEVIQGKADLIVAALTINNERAEWIEFSKPFKYQGLTILVKKNEQSNSLDSFLRPFQIHLWLLVLLSVHIVAVILYLLDRFSPFGRFKLARKEKEETALNLSSAMWFSWGVLLNSGIGEGTPRSFSARVL 616

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Nematostella
Match: EDO32623 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUK5])

HSP 1 Score: 45.8246 bits (107), Expect = 3.074e-6
Identity = 51/179 (28.49%), Postives = 73/179 (40.78%), Query Frame = 1

Query:   82 KTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESR---IWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            K TG   ++L IL+    F+  +YE+  +L G +     + ++ G  GDI + K+       T N  R   +DFS  FM  S    L   KPE +   I     P     W + + C +  +    L +YYSP     L       DE       W  + S L QG D  P  +S R V
Sbjct:   15 KYTGHSIDLLDILAGMNGFQYEIYESA-ELGGVK----EDGTYYGLFGDIQSEKADLTTLPLTINSARLQYLDFSEPFMHVS--MDLVTRKPEEKQIDITGFMTPYTIPVWLMTMACWIFVTGCLSLVNYYSPY-GHRLRDTEGDGDEFSFFNSLWFCLASMLQQGGDATPKMLSGRIV 185

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Medaka
Match: gria4b (glutamate receptor 4 [Source:NCBI gene;Acc:101175340])

HSP 1 Score: 51.6026 bits (122), Expect = 1.517e-7
Identity = 45/161 (27.95%), Postives = 70/161 (43.48%), Query Frame = 1

Query:  163 DKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFR---PLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIID---------EIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            D  +GAR  +     + G +G++  GK+    +  T    R+  +DFS  FM  S   S+   KP+     +F    PL +  W  I+   +  SV+ +L S +SP   W+   P    D         E  +    W  +G+F+ QG D  P S+S R V
Sbjct:  407 DGKYGAR--DPETKIWNGMVGELVYGKAEIAVAPLTITLVREEVIDFSKPFM--SLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE-WHTEEPEEGTDGQPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIV 562

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Medaka
Match: grik5 (glutamate ionotropic receptor kainate type subunit 5 [Source:NCBI gene;Acc:101174774])

HSP 1 Score: 50.8322 bits (120), Expect = 3.103e-7
Identity = 47/183 (25.68%), Postives = 81/183 (44.26%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDE--SNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIR--------LREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            G   +ML+ L+  ++F   +   +D L+GA   N S   +TG +G++ N K+    + FT   +R+  +DFS  FM    S    +Q  + +   +    P     W  ++L  +  S + +L +  SP   +N   P   + E R        L    W  +G F+ QG +  P ++S R V
Sbjct:  444 GFCVDMLRELADILKFSFKIKLVDDGLYGAPEPNGS---WTGMVGELINRKADLAVAAFTITSEREKVIDFSKPFMTLGISILYRVQLGR-KPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYN---PHPCMRERRDMLENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCV 619

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Medaka
Match: grik5 (glutamate ionotropic receptor kainate type subunit 5 [Source:NCBI gene;Acc:101174774])

HSP 1 Score: 50.8322 bits (120), Expect = 3.281e-7
Identity = 47/183 (25.68%), Postives = 81/183 (44.26%), Query Frame = 1

Query:   91 GIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDE--SNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIR--------LREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            G   +ML+ L+  ++F   +   +D L+GA   N S   +TG +G++ N K+    + FT   +R+  +DFS  FM    S    +Q  + +   +    P     W  ++L  +  S + +L +  SP   +N   P   + E R        L    W  +G F+ QG +  P ++S R V
Sbjct:  454 GFCVDMLRELADILKFSFKIKLVDDGLYGAPEPNGS---WTGMVGELINRKADLAVAAFTITSEREKVIDFSKPFMTLGISILYRVQLGR-KPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYN---PHPCMRERRDMLENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCV 629

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Medaka
Match: gria2b (glutamate ionotropic receptor AMPA type subunit 2 [Source:NCBI gene;Acc:101168274])

HSP 1 Score: 50.447 bits (119), Expect = 3.968e-7
Identity = 47/187 (25.13%), Postives = 80/187 (42.78%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESR---IWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLN-------LPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTV 609
            E+  G   ++   ++    FK  L    D  +GAR  ++    + G +G++  GK+    +  T    R+  +DFS  FM  S   S+   KP+     ++    PL +  W  I+   +  SV+ +L S +SP   W+               +E  +    W  +G+F+ QG D  P S+S R V
Sbjct:  437 ERYEGYCVDLAAEIAKHCGFKYQLKIVGDGKYGAR--DAETKIWNGMVGELVYGKADIAVAPLTITLVREEVIDFSKPFM--SLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE-WHTEEYEDGQIQTNESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIV 618

[Close]

BLAST of PBPe domain-containing protein vs. Ensembl Medaka
Match: GRID1 (glutamate receptor ionotropic, delta-1 [Source:NCBI gene;Acc:101174819])

HSP 1 Score: 50.447 bits (119), Expect = 4.061e-7
Identity = 44/188 (23.40%), Postives = 84/188 (44.68%), Query Frame = 1

Query:   79 EKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESR--IWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSI-------IDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            ++  G   ++L  L+  + FK  +Y+  D  +G+++ N S   + G IGD+ N ++    S  T   +R+  VDFS  ++D      +   KPE +  I+ +F P  +  W  I   + +  V+ +L +    L + + +            +    L    W + G+F+ QG D    S++ R V+ 
Sbjct:  414 KRYKGFSIDVLDALAKILGFKYEIYQVADSKYGSQLPNGS---WNGMIGDLINKRADLAVSAITITPERENVVDFSKRYLDYR--VGILVRKPEEKINIFSLFAPFDFAVWACIAAAIPVVGVLIFLLNRLQALHSSSSSSQSLSHGRRSNGVGSGTLHSAIWIVYGAFVQQGGDGVVGSVALRIVMG 596

[Close]

BLAST of PBPe domain-containing protein vs. Planmine SMEST
Match: SMESG000069533.1 (SMESG000069533.1)

HSP 1 Score: 246.128 bits (627), Expect = 1.270e-78
Identity = 116/195 (59.49%), Postives = 146/195 (74.87%), Query Frame = 1

Query:   31 IFPALNFLENGTYLPLEKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            IFPAL +    +++ L  TTG+I+E+L ILS K+ F PLLYEA D  WGAR  +S N  FTGCIGDI+N K+LFG S+FT N  R  GVDF+  F +ESN A L+F    S+IW++FRPL W+TW +I++  +  S + Y+ S YSPLSAWNL L F+++DEIRLREH WNI+GSFLMQGQDFYPYSMS+RTVLA
Sbjct:  243 IFPALTYTRKNSFVELNGTTGLIFEILSILSAKLNFIPLLYEAADSQWGARKNDSFN--FTGCIGDIFNKKTLFGASLFTINAMRNEGVDFTAPFFEESNSALLRFSTSNSKIWNVFRPLHWSTWLMILVSTIFASYVSYILSCYSPLSAWNLKLSFTVLDEIRLREHIWNIVGSFLMQGQDFYPYSMSSRTVLA 435

[Close]

BLAST of PBPe domain-containing protein vs. Planmine SMEST
Match: SMESG000069533.1 (SMESG000069533.1)

HSP 1 Score: 245.743 bits (626), Expect = 1.365e-78
Identity = 116/195 (59.49%), Postives = 146/195 (74.87%), Query Frame = 1

Query:   31 IFPALNFLENGTYLPLEKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            IFPAL +    +++ L  TTG+I+E+L ILS K+ F PLLYEA D  WGAR  +S N  FTGCIGDI+N K+LFG S+FT N  R  GVDF+  F +ESN A L+F    S+IW++FRPL W+TW +I++  +  S + Y+ S YSPLSAWNL L F+++DEIRLREH WNI+GSFLMQGQDFYPYSMS+RTVLA
Sbjct:  241 IFPALTYTRKNSFVELNGTTGLIFEILSILSAKLNFIPLLYEAADSQWGARKNDSFN--FTGCIGDIFNKKTLFGASLFTINAMRNEGVDFTAPFFEESNSALLRFSTSNSKIWNVFRPLHWSTWLMILVSTIFASYVSYILSCYSPLSAWNLKLSFTVLDEIRLREHIWNIVGSFLMQGQDFYPYSMSSRTVLA 433

[Close]

BLAST of PBPe domain-containing protein vs. Planmine SMEST
Match: SMESG000018611.1 (SMESG000018611.1)

HSP 1 Score: 200.675 bits (509), Expect = 3.668e-59
Identity = 99/195 (50.77%), Postives = 136/195 (69.74%), Query Frame = 1

Query:   31 IFPALNFLENGTYLPLEKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            I PA+ F  N  Y  +E+T G++ ++LKILS K+ F+ L+YEA DK +GARI N+SN  FTGC+G++ N K+ F    FT    R+  VD+S   M+ESN   LQ  K ++++WHIFRP  W+ W L I  + + S   Y+FS Y+PLSA+NLNL F+I+DEI ++EH WN IG F++QGQDFYPY++SAR VLA
Sbjct:  548 ITPAMIFPGNDKYYRIEETFGLVSDILKILSKKLNFRMLIYEAPDKQFGARIGNTSN--FTGCVGELLNKKATFAAGAFTFTSQRQEFVDYSYPIMEESNVPVLQKPKTQTKMWHIFRPFNWSVWLLSIATIFLISYFCYVFSKYNPLSAYNLNLNFAIVDEIYIKEHLWNAIGGFVLQGQDFYPYTVSARIVLA 740

HSP 2 Score: 170.629 bits (431), Expect = 8.353e-49
Identity = 86/182 (47.25%), Postives = 124/182 (68.13%), Query Frame = 1

Query:   70 LPLEKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            L + +TTG++  +L+ L   + FK L+YEA DK +G +I NSS   FTGCIG++   K++F   ++T    R   VDFS  +M+ESN   L+     S+IWH+ RPL ++ W LI++ +   S+  + FS +SPLSAWNLNL F+IIDE++L+E+ WN+IGS  MQGQDFYP+ +S+R VLA
Sbjct:    2 LYVNETTGLVPMILQGLEKFLSFKALIYEAPDKQFGTKIGNSS--KFTGCIGEVLEKKTVFSAGMYTLTSQRNEFVDFSNPYMEESNVPLLRKPLRSSKIWHVLRPLQFSVWMLILVSVAFVSLCCFSFSKFSPLSAWNLNLNFAIIDEVKLKENTWNVIGSLFMQGQDFYPFCISSRIVLA 181

[Close]

BLAST of PBPe domain-containing protein vs. Planmine SMEST
Match: SMESG000018611.1 (SMESG000018611.1)

HSP 1 Score: 200.29 bits (508), Expect = 4.523e-59
Identity = 99/195 (50.77%), Postives = 136/195 (69.74%), Query Frame = 1

Query:   31 IFPALNFLENGTYLPLEKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            I PA+ F  N  Y  +E+T G++ ++LKILS K+ F+ L+YEA DK +GARI N+SN  FTGC+G++ N K+ F    FT    R+  VD+S   M+ESN   LQ  K ++++WHIFRP  W+ W L I  + + S   Y+FS Y+PLSA+NLNL F+I+DEI ++EH WN IG F++QGQDFYPY++SAR VLA
Sbjct:  548 ITPAMIFPGNDKYYRIEETFGLVSDILKILSKKLNFRMLIYEAPDKQFGARIGNTSN--FTGCVGELLNKKATFAAGAFTFTSQRQEFVDYSYPIMEESNVPVLQKPKTQTKMWHIFRPFNWSVWLLSIATIFLISYFCYVFSKYNPLSAYNLNLNFAIVDEIYIKEHLWNAIGGFVLQGQDFYPYTVSARIVLA 740

HSP 2 Score: 170.244 bits (430), Expect = 1.179e-48
Identity = 86/182 (47.25%), Postives = 124/182 (68.13%), Query Frame = 1

Query:   70 LPLEKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            L + +TTG++  +L+ L   + FK L+YEA DK +G +I NSS   FTGCIG++   K++F   ++T    R   VDFS  +M+ESN   L+     S+IWH+ RPL ++ W LI++ +   S+  + FS +SPLSAWNLNL F+IIDE++L+E+ WN+IGS  MQGQDFYP+ +S+R VLA
Sbjct:    2 LYVNETTGLVPMILQGLEKFLSFKALIYEAPDKQFGTKIGNSS--KFTGCIGEVLEKKTVFSAGMYTLTSQRNEFVDFSNPYMEESNVPLLRKPLRSSKIWHVLRPLQFSVWMLILVSVAFVSLCCFSFSKFSPLSAWNLNLNFAIIDEVKLKENTWNVIGSLFMQGQDFYPFCISSRIVLA 181

[Close]

BLAST of PBPe domain-containing protein vs. Planmine SMEST
Match: SMESG000018611.1 (SMESG000018611.1)

HSP 1 Score: 170.244 bits (430), Expect = 3.805e-51
Identity = 86/182 (47.25%), Postives = 124/182 (68.13%), Query Frame = 1

Query:   70 LPLEKTTGIIYEMLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFGPSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTWTLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGSFLMQGQDFYPYSMSARTVLA 615
            L + +TTG++  +L+ L   + FK L+YEA DK +G +I NSS   FTGCIG++   K++F   ++T    R   VDFS  +M+ESN   L+     S+IWH+ RPL ++ W LI++ +   S+  + FS +SPLSAWNLNL F+IIDE++L+E+ WN+IGS  MQGQDFYP+ +S+R VLA
Sbjct:    2 LYVNETTGLVPMILQGLEKFLSFKALIYEAPDKQFGTKIGNSS--KFTGCIGEVLEKKTVFSAGMYTLTSQRNEFVDFSNPYMEESNVPLLRKPLRSSKIWHVLRPLQFSVWMLILVSVAFVSLCCFSFSKFSPLSAWNLNLNFAIIDEVKLKENTWNVIGSLFMQGQDFYPFCISSRIVLA 181

The following BLAST results are available for this feature:

BLAST of PBPe domain-containing protein vs. Ensembl Human
BLAST of PBPe domain-containing protein vs. Ensembl Celegans
BLAST of PBPe domain-containing protein vs. Ensembl Fly
BLAST of PBPe domain-containing protein vs. Ensembl Zebrafish
BLAST of PBPe domain-containing protein vs. Ensembl Xenopus
BLAST of PBPe domain-containing protein vs. Ensembl Mouse
BLAST of PBPe domain-containing protein vs. UniProt/SwissProt
BLAST of PBPe domain-containing protein vs. TrEMBL
BLAST of PBPe domain-containing protein vs. Ensembl Cavefish
BLAST of PBPe domain-containing protein vs. Ensembl Sea Lamprey
BLAST of PBPe domain-containing protein vs. Ensembl Yeast
BLAST of PBPe domain-containing protein vs. Ensembl Nematostella
BLAST of PBPe domain-containing protein vs. Ensembl Medaka
BLAST of PBPe domain-containing protein vs. Planmine SMEST

BLAST of PBPe domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
GRID1	3.545e-10	25.42	glutamate ionotropic receptor delta type subunit 1...	[more]
GRID1	3.984e-10	25.42	glutamate ionotropic receptor delta type subunit 1...	[more]
GRIK5	1.077e-7	25.68	glutamate ionotropic receptor kainate type subunit...	[more]
GRIK5	1.311e-7	25.68	glutamate ionotropic receptor kainate type subunit...	[more]
GRIK5	1.311e-7	25.68	glutamate ionotropic receptor kainate type subunit...	[more]

BLAST of PBPe domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
glr-1	6.700e-11	27.62	Glutamate receptor 1 [Source:UniProtKB/Swiss-Prot...	[more]
glr-7	4.664e-8	24.58	GLutamate Receptor family (AMPA) [Source:UniProtK...	[more]
glr-7	5.586e-8	24.58	GLutamate Receptor family (AMPA) [Source:UniProtK...	[more]
glr-7	6.270e-8	24.58	GLutamate Receptor family (AMPA) [Source:UniProtK...	[more]
glr-2	1.199e-7	25.42	Glutamate receptor 2 [Source:UniProtKB/Swiss-Prot...	[more]

BLAST of PBPe domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ekar	7.055e-10	25.54	gene:FBgn0039916 transcript:FBtr0089102	[more]
Ekar	7.342e-10	25.54	gene:FBgn0039916 transcript:FBtr0110906	[more]
Ekar	1.753e-8	26.09	gene:FBgn0039916 transcript:FBtr0344874	[more]
CG11155	3.362e-7	22.78	gene:FBgn0039927 transcript:FBtr0333701	[more]
CG11155	3.362e-7	22.78	gene:FBgn0039927 transcript:FBtr0089195	[more]

BLAST of PBPe domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
grid1b	3.685e-9	26.09	glutamate receptor, ionotropic, delta 1b [Source:Z...	[more]
gria2a	1.733e-8	25.67	glutamate receptor, ionotropic, AMPA 2a [Source:ZF...	[more]
gria2a	1.896e-8	25.67	glutamate receptor, ionotropic, AMPA 2a [Source:ZF...	[more]
gria2a	1.896e-8	25.67	glutamate receptor, ionotropic, AMPA 2a [Source:ZF...	[more]
grid1b	2.607e-8	26.04	glutamate receptor, ionotropic, delta 1b [Source:Z...	[more]

BLAST of PBPe domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ogfr	2.192e-8	26.09	opioid growth factor receptor [Source:Xenbase;Acc:...	[more]
ogfr	5.160e-8	26.09	opioid growth factor receptor [Source:Xenbase;Acc:...	[more]
ogfr	1.903e-7	26.67	opioid growth factor receptor [Source:Xenbase;Acc:...	[more]
ogfr	2.210e-7	26.67	opioid growth factor receptor [Source:Xenbase;Acc:...	[more]
ogfr	2.258e-7	26.67	opioid growth factor receptor [Source:Xenbase;Acc:...	[more]

BLAST of PBPe domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Grid1	2.520e-9	24.29	glutamate receptor, ionotropic, delta 1 [Source:MG...	[more]
Grik5	9.168e-8	25.68	glutamate receptor, ionotropic, kainate 5 (gamma 2...	[more]
Gria4	5.962e-7	27.50	glutamate receptor, ionotropic, AMPA4 (alpha 4) [S...	[more]
Gria4	5.962e-7	27.50	glutamate receptor, ionotropic, AMPA4 (alpha 4) [S...	[more]
Gria4	6.304e-7	27.50	glutamate receptor, ionotropic, AMPA4 (alpha 4) [S...	[more]

BLAST of PBPe domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P26591\|GLRK_LYMST	3.516e-10	26.92	Glutamate receptor OS=Lymnaea stagnalis OX=6523 PE...	[more]
sp\|P34299\|GLR1_CAEEL	8.522e-10	27.62	Glutamate receptor 1 OS=Caenorhabditis elegans OX=...	[more]
sp\|Q9ULK0\|GRID1_HUMAN	1.913e-9	25.42	Glutamate receptor ionotropic, delta-1 OS=Homo sap...	[more]
sp\|Q62640\|GRID1_RAT	1.682e-8	24.29	Glutamate receptor ionotropic, delta-1 OS=Rattus n...	[more]
sp\|Q61627\|GRID1_MOUSE	1.763e-8	24.29	Glutamate receptor ionotropic, delta-1 OS=Mus musc...	[more]

BLAST of PBPe domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1I8HAM9	3.454e-36	36.32	CCHC-type domain-containing protein OS=Macrostomum...	[more]
A0A1I8H5G6	1.724e-35	39.18	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A1I8J1L9	3.496e-35	39.18	PBPe domain-containing protein OS=Macrostomum lign...	[more]
A0A267FSX5	7.412e-35	38.07	PBPe domain-containing protein (Fragment) OS=Macro...	[more]
A0A267H134	3.782e-34	37.50	PBPe domain-containing protein (Fragment) OS=Macro...	[more]

BLAST of PBPe domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
GRID1	3.278e-11	27.47	glutamate ionotropic receptor delta type subunit 1...	[more]
GRID1	3.844e-11	27.47	glutamate ionotropic receptor delta type subunit 1...	[more]
grin3bb	1.194e-7	28.17	glutamate receptor, ionotropic, N-methyl-D-asparta...	[more]
grin3bb	1.333e-7	28.17	glutamate receptor, ionotropic, N-methyl-D-asparta...	[more]
grik5	1.387e-7	26.63	glutamate ionotropic receptor kainate type subunit...	[more]

BLAST of PBPe domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000010716.1	1.148e-6	26.36	pep scaffold:Pmarinus_7.0:GL476465:413535:454465:1...	[more]
ENSPMAT00000000889.1	3.794e-6	25.74	pep scaffold:Pmarinus_7.0:GL476542:184998:205948:1...	[more]

BLAST of PBPe domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PBPe domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3


Match Name	E-value	Identity	Description
EDO30203	1.326e-6	23.16	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35545	1.602e-6	23.89	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32623	3.074e-6	28.49	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of PBPe domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gria4b	1.517e-7	27.95	glutamate receptor 4 [Source:NCBI gene;Acc:1011753...	[more]
grik5	3.103e-7	25.68	glutamate ionotropic receptor kainate type subunit...	[more]
grik5	3.281e-7	25.68	glutamate ionotropic receptor kainate type subunit...	[more]
gria2b	3.968e-7	25.13	glutamate ionotropic receptor AMPA type subunit 2 ...	[more]
GRID1	4.061e-7	23.40	glutamate receptor ionotropic, delta-1 [Source:NCB...	[more]

BLAST of PBPe domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000069533.1	1.270e-78	59.49	SMESG000069533.1	[more]
SMESG000069533.1	1.365e-78	59.49	SMESG000069533.1	[more]
SMESG000018611.1	3.668e-59	50.77	SMESG000018611.1	[more]
SMESG000018611.1	4.523e-59	50.77	SMESG000018611.1	[more]
SMESG000018611.1	3.805e-51	47.25	SMESG000018611.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30009951 ID=SMED30009951|Name=PBPe domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=621bp
GTCGCCGAATTTCTTCTCCATTCATTGTAGATTTTTCCTGCTCTAAATTT
CCTTGAAAATGGTACTTATTTGCCATTGGAGAAGACTACTGGAATAATTT
ATGAAATGCTAAAGATTCTCTCTGTTAAGATGCAATTCAAACCATTATTA
TATGAAGCAGAAGATAAACTTTGGGGAGCTCGAATAAAGAATTCTTCCAA
TTTGAGCTTCACAGGCTGCATTGGAGACATATATAATGGAAAATCCTTGT
TTGGGCCTTCAGTTTTTACACCAAATTATGATCGAAAATTAGGAGTTGAT
TTCTCGGTTTTATTTATGGATGAGTCGAATTGCGCTTCTCTACAATTTTT
CAAACCCGAATCAAGAATATGGCACATATTTCGTCCACTTTTCTGGACAA
CATGGACATTGATAATTCTGTGCCTCGTCATAAATTCCGTCATCGGTTAT
TTATTTTCATATTATAGTCCATTGTCGGCCTGGAACCTCAACTTGCCGTT
TTCAATTATAGATGAAATCAGGCTCCGAGAACATTTTTGGAATATTATTG
GATCCTTCCTTATGCAAGGACAAGACTTCTATCCTTATTCAATGTCGGCA
AGAACGGTTTTAGCGTTTTAG

protein sequence of SMED30009951-orf-1

>SMED30009951-orf-1 ID=SMED30009951-orf-1|Name=SMED30009951-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=172bp
MLKILSVKMQFKPLLYEAEDKLWGARIKNSSNLSFTGCIGDIYNGKSLFG
PSVFTPNYDRKLGVDFSVLFMDESNCASLQFFKPESRIWHIFRPLFWTTW
TLIILCLVINSVIGYLFSYYSPLSAWNLNLPFSIIDEIRLREHFWNIIGS
FLMQGQDFYPYSMSARTVLAF*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0015276	ligand-gated ion channel activity
GO:0038023	signaling receptor activity
GO:0004970	ionotropic glutamate receptor activity
GO:0005234	extracellular-glutamate-gated ion channel activity
GO:0004872	receptor activity
GO:0005216	ion channel activity
GO:0005515	protein binding
GO:0008066	glutamate receptor activity
GO:0042802	identical protein binding
GO:0015277	kainate selective glutamate receptor activity
GO:0017124	SH3 domain binding
GO:0030165	PDZ domain binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000418	head
PLANA:0002089	reproductive organ

Vocabulary: **INTERPRO**
Term	Definition
IPR019594	Glu/Gly-bd
IPR001320	Iontro_rcpt

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0005783	endoplasmic reticulum
GO:0005886	plasma membrane
GO:0008328	ionotropic glutamate receptor complex
GO:0042734	presynaptic membrane
GO:0043005	neuron projection
GO:0043025	neuronal cell body
GO:0043195	terminal bouton
GO:0043204	perikaryon
GO:0045202	synapse
GO:0045211	postsynaptic membrane
GO:0014069	postsynaptic density
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0030424	axon
GO:0030425	dendrite
GO:0032983	kainate selective glutamate receptor complex

Vocabulary: **biological process**
Term	Definition
GO:0006621	protein retention in ER lumen
GO:0006810	transport
GO:0006811	ion transport
GO:0007268	chemical synaptic transmission
GO:0035235	ionotropic glutamate receptor signaling pathway
GO:0035249	synaptic transmission, glutamatergic
GO:0035725	sodium ion transmembrane transport
GO:0042391	regulation of membrane potential
GO:0043113	receptor clustering
GO:0043525	positive regulation of neuron apoptotic process
GO:0051649	establishment of localization in cell
GO:0060079	excitatory postsynaptic potential
GO:0071333	cellular response to glucose stimulus
GO:0071805	potassium ion transmembrane transport
GO:0031630	regulation of synaptic vesicle fusion to presynaptic active zone membrane
GO:0034220	ion transmembrane transport

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	GENE3D	G3DSA:1.10.287.70		coord: 87..171 e-value: 1.0E-10 score: 43.4
None	No IPR available	GENE3D	G3DSA:3.40.190.10		coord: 1..86 e-value: 8.7E-10 score: 40.4
None	No IPR available	PANTHER	PTHR18966:SF354		coord: 1..171
None	No IPR available	PANTHER	PTHR18966	IONOTROPIC GLUTAMATE RECEPTOR	coord: 1..171
None	No IPR available	TMHMM	TMhelix		coord: 97..119

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PBPe domain-containing protein

Zeng et. al., 2018

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Owlery

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