Beta-ureidopropionase

Overview
NameBeta-ureidopropionase
Smed IDSMED30009913
Length (bp)1469
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Beta-ureidopropionase (SMED30009913) t-SNE clustered cells

Violin plots show distribution of expression levels for Beta-ureidopropionase (SMED30009913) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Beta-ureidopropionase (SMED30009913) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Beta-ureidopropionase (SMED30009913) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30009913

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30009913h1SMcG0002832 Contig2599GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
pharynxSMED30009913h1SMcG0002832 dd_Smed_v4_1584_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30009913h1SMcG0002832 dd_Smed_v4_1584_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30009913h1SMcG0002832 dd_Smed_v4_1584_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30009913h1SMcG0002832 dd_Smed_v4_1584_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30009913h1SMcG0002832 dd_Smed_v4_1584_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30009913h1SMcG0002832 dd_Smed_v4_1584_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30009913h1SMcG0002832 Contig38385newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30009913h1SMcG0002832 Contig38385uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Human
Match: UPB1 (beta-ureidopropionase 1 [Source:HGNC Symbol;Acc:HGNC:16297])

HSP 1 Score: 496.508 bits (1277), Expect = 2.540e-174
Identity = 232/374 (62.03%), Postives = 287/374 (76.74%), Query Frame = 1 
Query:  160 MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKR--DVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVE 1275
            MA    +SLE+ L       DL+ V ++LYGK L  +++   A   A + + +LQG+ F A  E  R P+IV VG +QN+I L A+ PV++Q+ ALH RIK I+++A    VNIIC QEAWTMPF FCTREKLPW EFAE   +G TT+F  KLAK H MV++SPILERD    DV+WNTAV+I  +G  LGK+RKNHIPRVGDFNESTYYMEGNLGHPVF T +G+IAVNIC+GRH PLNWL+Y + GA+I+FNPSAT+  LSE+LWPIEARNAAIANH FT AINRVGTE FP++FTSGDGK+ H++FG+FYGSSY+ APD SRT GLSR +DGLL+A++DLNLC+Q+ D W F MT R EMYA++L E V+
Sbjct:    1 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFEAAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEAWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVK 374
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Human
Match: UPB1 (beta-ureidopropionase 1 [Source:HGNC Symbol;Acc:HGNC:16297])

HSP 1 Score: 105.531 bits (262), Expect = 7.517e-26
Identity = 53/123 (43.09%), Postives = 76/123 (61.79%), Query Frame = 1 
Query:  160 MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTM 528
            MA    +SLE+ L       DL+ V ++LYGK L  +++   A   A + + +LQG+ F A  E  R P+IV VG +QN+I L A+ PV++Q+ ALH RIK I+++A    VNIIC QEAW +
Sbjct:    1 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFEAAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEAWIL 123
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Human
Match: NIT1 (nitrilase 1 [Source:HGNC Symbol;Acc:HGNC:7828])

HSP 1 Score: 63.1586 bits (152), Expect = 2.961e-10
Identity = 55/200 (27.50%), Postives = 80/200 (40.00%), Query Frame = 1 
Query:  667 DKRDVIWNTAVIIDQNGNFLGKSRKNH-----IPRVGDFNESTYYMEG-NLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMY 1248
            ++   I+N  V+++  G  +   RK H     IP  G   ES   M G +L  PV  T  GKI + +C+    P   L     GA+I+  PSA         W +  R  AI    + VA  + G                H E    YG S +  P G+     S    GL +A +DLN  RQ++        +R ++Y
Sbjct:  137 EQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPV-STPAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAHWEVLLRARAIETQCYVVAAAQCGR---------------HHEKRASYGHSMVVDPWGTVVARCSE-GPGLCLARIDLNYLRQLRRHLPVFQHRRPDLY 319
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Human
Match: NIT1 (nitrilase 1 [Source:HGNC Symbol;Acc:HGNC:7828])

HSP 1 Score: 62.7734 bits (151), Expect = 3.387e-10
Identity = 55/200 (27.50%), Postives = 80/200 (40.00%), Query Frame = 1 
Query:  667 DKRDVIWNTAVIIDQNGNFLGKSRKNH-----IPRVGDFNESTYYMEG-NLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMY 1248
            ++   I+N  V+++  G  +   RK H     IP  G   ES   M G +L  PV  T  GKI + +C+    P   L     GA+I+  PSA         W +  R  AI    + VA  + G                H E    YG S +  P G+     S    GL +A +DLN  RQ++        +R ++Y
Sbjct:  101 EQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPV-STPAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAHWEVLLRARAIETQCYVVAAAQCGR---------------HHEKRASYGHSMVVDPWGTVVARCSE-GPGLCLARIDLNYLRQLRRHLPVFQHRRPDLY 283
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Human
Match: NIT1 (nitrilase 1 [Source:HGNC Symbol;Acc:HGNC:7828])

HSP 1 Score: 62.3882 bits (150), Expect = 4.198e-10
Identity = 55/200 (27.50%), Postives = 80/200 (40.00%), Query Frame = 1 
Query:  667 DKRDVIWNTAVIIDQNGNFLGKSRKNH-----IPRVGDFNESTYYMEG-NLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMY 1248
            ++   I+N  V+++  G  +   RK H     IP  G   ES   M G +L  PV  T  GKI + +C+    P   L     GA+I+  PSA         W +  R  AI    + VA  + G                H E    YG S +  P G+     S    GL +A +DLN  RQ++        +R ++Y
Sbjct:  122 EQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPV-STPAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAHWEVLLRARAIETQCYVVAAAQCGR---------------HHEKRASYGHSMVVDPWGTVVARCSE-GPGLCLARIDLNYLRQLRRHLPVFQHRRPDLY 304
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Celegans
Match: upb-1 (UreidoPropionase Beta [Source:UniProtKB/TrEMBL;Acc:Q19437])

HSP 1 Score: 470.7 bits (1210), Expect = 1.616e-164
Identity = 223/370 (60.27%), Postives = 271/370 (73.24%), Query Frame = 1 
Query:  163 AKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERD--KRDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQE 1266
            A    + +E  L    D   L+ V ++LYG+    + I   A   A+  +  L G+   A+ E TR P++VRV AIQN+I    ++ V +Q  A+H R+  +I+ A     N+I LQEAWTMPF FCTRE+LPW EFAE +  G TTQFL KLA  H +VIISPILERD  K DVIWNTAV+I   G  +G+SRKNHIPRVGDFNESTYYME  LGHPVF+T YG+I +NIC+GRH P NW++Y L GA+I+FNPSATV  LSE LW IEARNAAIANH FTV INRVGTEVFP++FTSG+G+  HK+FGHFYGSSYI APDGSRT  LSRV++G+LIAE+DLNLCRQ KD WGF MT RL+MYA+K+ E
Sbjct:    4 APAQFDGVETALAEKLDGVSLDEVERILYGRPYRALEISSIAEKLAQDGDFQLSGYIVDAQKEQTRAPRLVRVAAIQNKIHRPTTDSVVEQRDAIHQRVGAMIEAAASAGANVIGLQEAWTMPFAFCTRERLPWTEFAESVYTGPTTQFLSKLAVKHDIVIISPILERDEEKDDVIWNTAVVISHTGRVIGRSRKNHIPRVGDFNESTYYMESTLGHPVFETKYGRIGINICYGRHHPQNWMMYALNGAEIIFNPSATVGALSEPLWGIEARNAAIANHVFTVGINRVGTEVFPNEFTSGNGQPAHKDFGHFYGSSYIAAPDGSRTPALSRVREGVLIAELDLNLCRQCKDAWGFRMTNRLDMYAQKITE 373
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Celegans
Match: nft-1 (Nitrilase and fragile histidine triad fusion protein NitFhit Bis(5'-adenosyl)-triphosphatase Nitrilase homolog [Source:UniProtKB/Swiss-Prot;Acc:O76463])

HSP 1 Score: 60.4622 bits (145), Expect = 1.455e-9
Identity = 69/282 (24.47%), Postives = 111/282 (39.36%), Query Frame = 1 
Query:  460 KKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPW-----CEFAERIPEGLTTQFLCKLAKTHSM-VIISPILERDKRDVI--WNTAVIIDQNGNFLGKSRKNH-----IPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQE 1266
            K +I+ AG+ K  ++ L E +    G    E++       CE+ E+  E         LA+ H++ + +  +  +D  D    WNT +IID +G    +  K H     IP      ES +   G    P  DT  G++ ++IC+    P   L     GAQ++  PSA         W    R  AI N  + VA  + G                H      YG S +  P G+     S   D +  AE+DL+    +++       +R ++Y   + E
Sbjct:   36 KNMIERAGEKKCEMVFLPECFDF-IGLNKNEQIDLAMATDCEYMEKYRE---------LARKHNIWLSLGGLHHKDPSDAAHPWNTHLIIDSDGVTRAEYNKLHLFDLEIPGKVRLMESEFSKAGTEMIPPVDTPIGRLGLSICYDVRFPELSLWNRKRGAQLLSFPSAFTLNTGLAHWETLLRARAIENQCYVVAAAQTGA---------------HNPKRQSYGHSMVVDPWGAVVAQCSERVD-MCFAEIDLSYVDTLREMQPVFSHRRSDLYTLHINE 291
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Fly
Match: pyd3 (gene:FBgn0037513 transcript:FBtr0081780)

HSP 1 Score: 462.611 bits (1189), Expect = 2.427e-161
Identity = 215/356 (60.39%), Postives = 273/356 (76.69%), Query Frame = 1 
Query:  217 EDLEYVTKLLYG-KSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKR--DVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVE 1275
            ++L+ V ++LYG +  +T+ +  +A + A+Q   D++G+RF A+ E TR  +IVRVGAIQN IV+  + P+  Q  A+ +++K +I  A +   NI+C QEAWTMPF FCTREK PWCEFAE    G TT+ L +LAK ++MVII  ILERD    + IWNTAV+I  +G +LGK RKNHIPRVGDFNESTYYMEGN GHPVF+T +GK+AVNIC+GRH P NW+++GL GA+IVFNPSAT+  LSE LW IEARNAAIAN YFTV INRVGTE FP+++TSGDG + HKEFG FYGSSY+ APDGSRT  LSR +DGLL+ E+DLNLCRQ+KD WGF MTQR+ +YA+  ++  E
Sbjct:   20 DELKEVKRILYGVEEDQTLELPTSAKDIAEQNGFDIKGYRFTAREEQTRKRRIVRVGAIQNSIVIPTTAPIEKQREAIWNKVKTMIKAAAEAGCNIVCTQEAWTMPFAFCTREKFPWCEFAEEAENGPTTKMLAELAKAYNMVIIHSILERDMEHGETIWNTAVVISNSGRYLGKHRKNHIPRVGDFNESTYYMEGNTGHPVFETEFGKLAVNICYGRHHPQNWMMFGLNGAEIVFNPSATIGRLSEPLWSIEARNAAIANSYFTVPINRVGTEQFPNEYTSGDGNKAHKEFGPFYGSSYVAAPDGSRTPSLSRDKDGLLVVELDLNLCRQVKDFWGFRMTQRVPLYAESFKKASE 375
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Zebrafish
Match: upb1 (ureidopropionase, beta [Source:ZFIN;Acc:ZDB-GENE-030131-1380])

HSP 1 Score: 491.115 bits (1263), Expect = 2.321e-172
Identity = 228/374 (60.96%), Postives = 289/374 (77.27%), Query Frame = 1 
Query:  160 MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDK--RDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVE 1275
            M+ K  ESLEK+L       +L+   +LL+GK L+ +++  +A++ A Q + DL+G+ F A  E  R P++VRVG IQN+IVL    PV +QI ALH R+ +++++A    VNI+C QEAWTMPF FCTRE+ PW EFAE   +GLTT+F  +LAK H+MV++SPILERD+     +WNTAV++  NGN LGK+RKNHIPRVGDFNESTYYMEGN GH VF T +GKIAVNIC+GRH PLNWL+Y + GA+I+FNPSATV  LSE +WPIEARNAAIANH FT AINRVGTE F ++FTSGDGK+ H +FGHFYGSSY+ APDGSRT GLSR +DGLL+AE+DLNL RQ+ D+W F MT R EMYA++L++ V+
Sbjct:    1 MSGKDFESLEKVLEAHLPEAELKEARRLLFGKELKKLDLPRSAIDAAGQQDFDLKGYVFEASPEQLRPPRMVRVGLIQNKIVLPTDAPVLEQITALHKRVGEMVEVAAMCGVNIVCFQEAWTMPFAFCTREREPWTEFAESAEDGLTTRFCIQLAKKHNMVVVSPILERDEIHGGTLWNTAVVVSNNGNVLGKTRKNHIPRVGDFNESTYYMEGNTGHRVFQTQFGKIAVNICYGRHHPLNWLMYSVNGAEIIFNPSATVGLLSEPMWPIEARNAAIANHCFTCAINRVGTEYFKNEFTSGDGKKAHHDFGHFYGSSYMAAPDGSRTPGLSRTRDGLLVAELDLNLNRQVADKWNFKMTGRYEMYAEELKKAVQ 374
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Zebrafish
Match: upb1 (ureidopropionase, beta [Source:ZFIN;Acc:ZDB-GENE-030131-1380])

HSP 1 Score: 491.115 bits (1263), Expect = 2.321e-172
Identity = 228/374 (60.96%), Postives = 289/374 (77.27%), Query Frame = 1 
Query:  160 MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDK--RDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVE 1275
            M+ K  ESLEK+L       +L+   +LL+GK L+ +++  +A++ A Q + DL+G+ F A  E  R P++VRVG IQN+IVL    PV +QI ALH R+ +++++A    VNI+C QEAWTMPF FCTRE+ PW EFAE   +GLTT+F  +LAK H+MV++SPILERD+     +WNTAV++  NGN LGK+RKNHIPRVGDFNESTYYMEGN GH VF T +GKIAVNIC+GRH PLNWL+Y + GA+I+FNPSATV  LSE +WPIEARNAAIANH FT AINRVGTE F ++FTSGDGK+ H +FGHFYGSSY+ APDGSRT GLSR +DGLL+AE+DLNL RQ+ D+W F MT R EMYA++L++ V+
Sbjct:    1 MSGKDFESLEKVLEAHLPEAELKEARRLLFGKELKKLDLPRSAIDAAGQQDFDLKGYVFEASPEQLRPPRMVRVGLIQNKIVLPTDAPVLEQITALHKRVGEMVEVAAMCGVNIVCFQEAWTMPFAFCTREREPWTEFAESAEDGLTTRFCIQLAKKHNMVVVSPILERDEIHGGTLWNTAVVVSNNGNVLGKTRKNHIPRVGDFNESTYYMEGNTGHRVFQTQFGKIAVNICYGRHHPLNWLMYSVNGAEIIFNPSATVGLLSEPMWPIEARNAAIANHCFTCAINRVGTEYFKNEFTSGDGKKAHHDFGHFYGSSYMAAPDGSRTPGLSRTRDGLLVAELDLNLNRQVADKWNFKMTGRYEMYAEELKKAVQ 374
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Zebrafish
Match: upb1 (ureidopropionase, beta [Source:ZFIN;Acc:ZDB-GENE-030131-1380])

HSP 1 Score: 263.077 bits (671), Expect = 1.255e-84
Identity = 120/169 (71.01%), Postives = 142/169 (84.02%), Query Frame = 1 
Query:  769 NESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVE 1275
            N STYYMEGN GH VF T +GKIAVNIC+GRH PLNWL+Y + GA+I+FNPSATV  LSE +WPIEARNAAIANH FT AINRVGTE F ++FTSGDGK+ H +FGHFYGSSY+ APDGSRT GLSR +DGLL+AE+DLNL RQ+ D+W F MT R EMYA++L++ V+
Sbjct:  110 NVSTYYMEGNTGHRVFQTQFGKIAVNICYGRHHPLNWLMYSVNGAEIIFNPSATVGLLSEPMWPIEARNAAIANHCFTCAINRVGTEYFKNEFTSGDGKKAHHDFGHFYGSSYMAAPDGSRTPGLSRTRDGLLVAELDLNLNRQVADKWNFKMTGRYEMYAEELKKAVQ 278
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Zebrafish
Match: nit2 (nitrilase family, member 2 [Source:NCBI gene;Acc:402904])

HSP 1 Score: 56.9954 bits (136), Expect = 1.384e-8
Identity = 61/271 (22.51%), Postives = 112/271 (41.33%), Query Frame = 1 
Query:  454 RIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKRDVIWNTAVIIDQNGNFLGKSRKNH-----IPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYA 1251
            R + ++  A      ++ L E +  P+G        + E+AE+IP G +TQ L + AK   + ++   +  +    ++NT  +   +G  L   RK H     +P    F ES     G     +F+T Y K+ V IC+         +Y  +G Q++  P A         W +  R  A+ N  +      V T     D T+      +  +GH   SS I       +K  S  ++ ++ A++DL     ++ +   +  +R ++Y+
Sbjct:   30 RAQTLVTEAAGQGAKVVVLPECFNSPYGTGF-----FKEYAEKIP-GESTQVLSETAKKCGIYLVGGSIPEEDGGKLYNTCSVFGPDGKLLVTHRKIHLFDIDVPGKIRFQESETLSPGK-SLSMFETPYCKVGVGICYDIRFAELAQIYAKKGCQLLVYPGAFNMTTGPAHWELLQRGRAVDNQVY------VATASPARDETAS-----YVAWGH---SSVINPWGEVISKAGS--EESVVYADIDLQYLADVRQQIPITKQRRNDLYS 277
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Zebrafish
Match: nit1 (nitrilase 1 [Source:ZFIN;Acc:ZDB-GENE-040912-65])

HSP 1 Score: 50.447 bits (119), Expect = 2.179e-6
Identity = 44/188 (23.40%), Postives = 71/188 (37.77%), Query Frame = 1 
Query:  667 DKRDVIWNTAVIIDQNGNFLGKSRKNHIPRVG------DFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDE 1212
            D+R  I+N+ +II+  G  +   RK H+  V          ES + + G    P   T  GK+ + +C+    P         GA+I+  PSA         W +  R  A+    F +A  +VG                H      YG +    P G         Q+G+ +A ++L   R I+ +
Sbjct:  126 DRR--IYNSHIIINGQGEIVSVYRKTHLFDVELSSKGVSLKESAFTIPGPRLVPPVQTPIGKVGLGVCYDLRFPELSAALQRHGAEILTYPSAFTVATGTAHWEVLLRARAVETQCFVLAAAQVGA---------------HHSKRASYGHALAVDPWGEVLGDCGGTQEGVTLAHINLQKLRDIRRD 296
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Xenopus
Match: upb1 (ureidopropionase, beta [Source:NCBI gene;Acc:100145317])

HSP 1 Score: 492.656 bits (1267), Expect = 7.722e-173
Identity = 227/351 (64.67%), Postives = 277/351 (78.92%), Query Frame = 1 
Query:  214 NEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDK--RDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKL 1260
            ++DL+ V +LLYGK +  +N+  +A   A +   DLQG+ F A  E TR P+ VRVG IQN+I L  +EPV++QI ALH RI +I+++A    VNI+C QEAW+MPF FCTREKLPW EFAE   +G+TT+F  +LAK H+MVI+SPILERD    D +WNTAVII   G  +GKSRKNHIPRVGDFNESTYYMEGN GH VF T +GKIAVNIC+GRH PLNW +Y + GA+I+FNPSAT+  LSE+LWPIEARNAAIANH FT +INRVGTE F ++FTSGDGK+ H +FGHFYGSSY++APDGSR+ GLSRV+DGLL+AEMDLNLCRQ  D+W F MT R EMYA++L
Sbjct:   18 SDDLKEVWRLLYGKQIRPLNLPNSASQAASKEGFDLQGYLFEAAQEQTRRPRTVRVGLIQNKIQLPTTEPVTEQISALHRRIAEIVEVAATCGVNIVCFQEAWSMPFAFCTREKLPWTEFAESAEDGMTTKFCQELAKKHNMVIVSPILERDSVHGDTLWNTAVIISNTGAVMGKSRKNHIPRVGDFNESTYYMEGNTGHRVFQTAFGKIAVNICYGRHHPLNWFMYSMNGAEIIFNPSATIGELSESLWPIEARNAAIANHCFTCSINRVGTEHFENEFTSGDGKKAHHDFGHFYGSSYVSAPDGSRSPGLSRVRDGLLVAEMDLNLCRQTSDKWNFKMTGRYEMYAEEL 368
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Xenopus
Match: upb1 (ureidopropionase, beta [Source:NCBI gene;Acc:100145317])

HSP 1 Score: 478.404 bits (1230), Expect = 1.346e-167
Identity = 220/335 (65.67%), Postives = 265/335 (79.10%), Query Frame = 1 
Query:  262 ETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDK--RDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKL 1260
            E +N+  +A   A +   DLQG+ F A  E TR P+ VRVG IQN+I L  +EPV++QI ALH RI +I+++A    VNI+C QEAW+MPF FCTREKLPW EFAE   +G+TT+F  +LAK H+MVI+SPILERD    D +WNTAVII   G  +GKSRKNHIPRVGDFNESTYYMEGN GH VF T +GKIAVNIC+GRH PLNW +Y + GA+I+FNPSAT+  LSE+LWPIEARNAAIANH FT +INRVGTE F ++FTSGDGK+ H +FGHFYGSSY++APDGSR+ GLSRV+DGLL+AEMDLNLCRQ  D+W F MT R EMYA++L
Sbjct:    9 EPLNLPNSASQAASKEGFDLQGYLFEAAQEQTRRPRTVRVGLIQNKIQLPTTEPVTEQISALHRRIAEIVEVAATCGVNIVCFQEAWSMPFAFCTREKLPWTEFAESAEDGMTTKFCQELAKKHNMVIVSPILERDSVHGDTLWNTAVIISNTGAVMGKSRKNHIPRVGDFNESTYYMEGNTGHRVFQTAFGKIAVNICYGRHHPLNWFMYSMNGAEIIFNPSATIGELSESLWPIEARNAAIANHCFTCSINRVGTEHFENEFTSGDGKKAHHDFGHFYGSSYVSAPDGSRSPGLSRVRDGLLVAEMDLNLCRQTSDKWNFKMTGRYEMYAEEL 343
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Xenopus
Match: upb1 (ureidopropionase, beta [Source:NCBI gene;Acc:100145317])

HSP 1 Score: 477.248 bits (1227), Expect = 6.006e-167
Identity = 219/333 (65.77%), Postives = 264/333 (79.28%), Query Frame = 1 
Query:  268 INIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDK--RDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKL 1260
            +N+  +A   A +   DLQG+ F A  E TR P+ VRVG IQN+I L  +EPV++QI ALH RI +I+++A    VNI+C QEAW+MPF FCTREKLPW EFAE   +G+TT+F  +LAK H+MVI+SPILERD    D +WNTAVII   G  +GKSRKNHIPRVGDFNESTYYMEGN GH VF T +GKIAVNIC+GRH PLNW +Y + GA+I+FNPSAT+  LSE+LWPIEARNAAIANH FT +INRVGTE F ++FTSGDGK+ H +FGHFYGSSY++APDGSR+ GLSRV+DGLL+AEMDLNLCRQ  D+W F MT R EMYA++L
Sbjct:   31 LNLPNSASQAASKEGFDLQGYLFEAAQEQTRRPRTVRVGLIQNKIQLPTTEPVTEQISALHRRIAEIVEVAATCGVNIVCFQEAWSMPFAFCTREKLPWTEFAESAEDGMTTKFCQELAKKHNMVIVSPILERDSVHGDTLWNTAVIISNTGAVMGKSRKNHIPRVGDFNESTYYMEGNTGHRVFQTAFGKIAVNICYGRHHPLNWFMYSMNGAEIIFNPSATIGELSESLWPIEARNAAIANHCFTCSINRVGTEHFENEFTSGDGKKAHHDFGHFYGSSYVSAPDGSRSPGLSRVRDGLLVAEMDLNLCRQTSDKWNFKMTGRYEMYAEEL 363
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Xenopus
Match: upb1 (ureidopropionase, beta [Source:NCBI gene;Acc:100145317])

HSP 1 Score: 476.093 bits (1224), Expect = 7.842e-167
Identity = 219/333 (65.77%), Postives = 264/333 (79.28%), Query Frame = 1 
Query:  268 INIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDK--RDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKL 1260
            +N+  +A   A +   DLQG+ F A  E TR P+ VRVG IQN+I L  +EPV++QI ALH RI +I+++A    VNI+C QEAW+MPF FCTREKLPW EFAE   +G+TT+F  +LAK H+MVI+SPILERD    D +WNTAVII   G  +GKSRKNHIPRVGDFNESTYYMEGN GH VF T +GKIAVNIC+GRH PLNW +Y + GA+I+FNPSAT+  LSE+LWPIEARNAAIANH FT +INRVGTE F ++FTSGDGK+ H +FGHFYGSSY++APDGSR+ GLSRV+DGLL+AEMDLNLCRQ  D+W F MT R EMYA++L
Sbjct:    9 LNLPNSASQAASKEGFDLQGYLFEAAQEQTRRPRTVRVGLIQNKIQLPTTEPVTEQISALHRRIAEIVEVAATCGVNIVCFQEAWSMPFAFCTREKLPWTEFAESAEDGMTTKFCQELAKKHNMVIVSPILERDSVHGDTLWNTAVIISNTGAVMGKSRKNHIPRVGDFNESTYYMEGNTGHRVFQTAFGKIAVNICYGRHHPLNWFMYSMNGAEIIFNPSATIGELSESLWPIEARNAAIANHCFTCSINRVGTEHFENEFTSGDGKKAHHDFGHFYGSSYVSAPDGSRSPGLSRVRDGLLVAEMDLNLCRQTSDKWNFKMTGRYEMYAEEL 341
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Xenopus
Match: upb1 (ureidopropionase, beta [Source:NCBI gene;Acc:100145317])

HSP 1 Score: 476.093 bits (1224), Expect = 9.369e-167
Identity = 220/337 (65.28%), Postives = 264/337 (78.34%), Query Frame = 1 
Query:  256 SLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDK--RDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKL 1260
            S +T +     V  A +   DLQG+ F A  E TR P+ VRVG IQN+I L  +EPV++QI ALH RI +I+++A    VNI+C QEAW+MPF FCTREKLPW EFAE   +G+TT+F  +LAK H+MVI+SPILERD    D +WNTAVII   G  +GKSRKNHIPRVGDFNESTYYMEGN GH VF T +GKIAVNIC+GRH PLNW +Y + GA+I+FNPSAT+  LSE+LWPIEARNAAIANH FT +INRVGTE F ++FTSGDGK+ H +FGHFYGSSY++APDGSR+ GLSRV+DGLL+AEMDLNLCRQ  D+W F MT R EMYA++L
Sbjct:   10 SAQTAHTSPIVVTAASKEGFDLQGYLFEAAQEQTRRPRTVRVGLIQNKIQLPTTEPVTEQISALHRRIAEIVEVAATCGVNIVCFQEAWSMPFAFCTREKLPWTEFAESAEDGMTTKFCQELAKKHNMVIVSPILERDSVHGDTLWNTAVIISNTGAVMGKSRKNHIPRVGDFNESTYYMEGNTGHRVFQTAFGKIAVNICYGRHHPLNWFMYSMNGAEIIFNPSATIGELSESLWPIEARNAAIANHCFTCSINRVGTEHFENEFTSGDGKKAHHDFGHFYGSSYVSAPDGSRSPGLSRVRDGLLVAEMDLNLCRQTSDKWNFKMTGRYEMYAEEL 346
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Mouse
Match: Upb1 (ureidopropionase, beta [Source:MGI Symbol;Acc:MGI:2143535])

HSP 1 Score: 490.73 bits (1262), Expect = 4.994e-172
Identity = 229/374 (61.23%), Postives = 285/374 (76.20%), Query Frame = 1 
Query:  160 MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKRD--VIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVE 1275
            MA    +SLE+ L      +DL  V ++LYGK    +++   A+  A + N +L+G+ F A  E  R PQIVRVG +QN+I L  S PV++Q+ ALH  I++I ++A    VNIIC QEAW MPF FCTREKLPW EFAE   +GLTT+F  KLAK H+MV++SPILERD+    V+WNTAV+I  +G  +GK+RKNHIPRVGDFNESTYYMEGNLGHPVF T +G+IAVNIC+GRH PLNWL+Y + GA+I+FNPSAT+  LSE+LWPIEARNAAIANH FT A+NRVG E FP++FTSGDGK+ H + G+FYGSSY+ APDGSRT GLSR QDGLL+ E++LNLC+QI D W F MT RLEMYA++L E V+
Sbjct:    1 MAGPEWQSLEQCLEKHLPPDDLAQVKRILYGKQTRNLDLPREALKAASERNFELKGYAFGAAKEQQRCPQIVRVGLVQNRIPLPTSAPVAEQVSALHKSIEEIAEVAAMCGVNIICFQEAWNMPFAFCTREKLPWTEFAESAEDGLTTRFCQKLAKKHNMVVVSPILERDREHGGVLWNTAVVISNSGLVMGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGELSESLWPIEARNAAIANHCFTCALNRVGQEHFPNEFTSGDGKKAHHDLGYFYGSSYVAAPDGSRTPGLSRNQDGLLVTELNLNLCQQINDFWTFKMTGRLEMYARELAEAVK 374
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Mouse
Match: Upb1 (ureidopropionase, beta [Source:MGI Symbol;Acc:MGI:2143535])

HSP 1 Score: 122.865 bits (307), Expect = 9.135e-33
Identity = 56/112 (50.00%), Postives = 74/112 (66.07%), Query Frame = 1 
Query:  259 LETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEG 594
               +++   A+  A + N +L+G+ F A  E  R PQIVRVG +QN+I L  S PV++Q+ ALH  I++I ++A    VNIIC QEAW MPF FCTREKLPW EFAE   +G
Sbjct:   39 FRNLDLPREALKAASERNFELKGYAFGAAKEQQRCPQIVRVGLVQNRIPLPTSAPVAEQVSALHKSIEEIAEVAAMCGVNIICFQEAWNMPFAFCTREKLPWTEFAESAEDG 150
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Mouse
Match: Nit2 (nitrilase family, member 2 [Source:MGI Symbol;Acc:MGI:1261838])

HSP 1 Score: 69.707 bits (169), Expect = 8.629e-13
Identity = 63/270 (23.33%), Postives = 114/270 (42.22%), Query Frame = 1 
Query:  454 RIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKRDVIWNTAVIIDQNGNFLGKSRKNH-----IPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMY 1248
            R   ++  A K   NI+ L E +  P+G        + ++AE+IP G +TQ L ++AK  S+ +I   +  +    ++NT  +   +G+ L K RK H     +P    F ES     G+     FDT Y K+ + IC+         +Y   G Q++  P A         W +  R  A+ N  +    +            + D K  +  +GH    S +  P G +    +  ++ +L +++DL    +I+ +      +R ++Y
Sbjct:   23 RACSLVREAAKQGANIVSLPECFNSPYGTTY-----FPDYAEKIP-GESTQKLSEVAKESSIYLIGGSIPEEDAGKLYNTCSVFGPDGSLLVKHRKIHLFDIDVPGKITFQESKTLSPGD-SFSTFDTPYCKVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNLTTGPAHWELLQRARAVDNQVYVATAS-----------PARDDKASYVAWGH----STVVDPWG-QVLTKAGTEETILYSDIDLKKLAEIRQQIPILKQKRADLY 269
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Mouse
Match: Nit1 (nitrilase 1 [Source:MGI Symbol;Acc:MGI:1350916])

HSP 1 Score: 65.0846 bits (157), Expect = 4.269e-11
Identity = 50/201 (24.88%), Postives = 79/201 (39.30%), Query Frame = 1 
Query:  667 DKRDVIWNTAVIIDQNGNFLGKSRKNH-----IPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAK 1254
            ++   I+N  V+++  G+ +   RK H     IP  G   ES Y   G    P   T  GK+ + IC+    P   L     GA+I+  PSA         W +  R  AI +  + +A  + G                H E    YG S +  P G+     S    GL +A +DL+  +Q++        +R ++Y  
Sbjct:  133 EQNQKIYNCHVLLNSKGSVVASYRKTHLCDVEIPGQGPMRESNYTKPGGTLEPPVKTPAGKVGLAICYDMRFPELSLKLAQAGAEILTYPSAFGSVTGPAHWEVLLRARAIESQCYVIAAAQCGR---------------HHETRASYGHSMVVDPWGTVVARCSE-GPGLCLARIDLHFLQQMRQHLPVFQHRRPDLYGS 317
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Mouse
Match: Nit1 (nitrilase 1 [Source:MGI Symbol;Acc:MGI:1350916])

HSP 1 Score: 64.6994 bits (156), Expect = 4.587e-11
Identity = 50/201 (24.88%), Postives = 79/201 (39.30%), Query Frame = 1 
Query:  667 DKRDVIWNTAVIIDQNGNFLGKSRKNH-----IPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAK 1254
            ++   I+N  V+++  G+ +   RK H     IP  G   ES Y   G    P   T  GK+ + IC+    P   L     GA+I+  PSA         W +  R  AI +  + +A  + G                H E    YG S +  P G+     S    GL +A +DL+  +Q++        +R ++Y  
Sbjct:  100 EQNQKIYNCHVLLNSKGSVVASYRKTHLCDVEIPGQGPMRESNYTKPGGTLEPPVKTPAGKVGLAICYDMRFPELSLKLAQAGAEILTYPSAFGSVTGPAHWEVLLRARAIESQCYVIAAAQCGR---------------HHETRASYGHSMVVDPWGTVVARCSE-GPGLCLARIDLHFLQQMRQHLPVFQHRRPDLYGS 284
[Close]
BLAST of Beta-ureidopropionase vs. UniProt/SwissProt
Match: sp|Q5RBM6|BUP1_PONAB (Beta-ureidopropionase OS=Pongo abelii OX=9601 GN=UPB1 PE=2 SV=1)

HSP 1 Score: 496.893 bits (1278), Expect = 7.713e-174
Identity = 233/374 (62.30%), Postives = 287/374 (76.74%), Query Frame = 1 
Query:  160 MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKR--DVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVE 1275
            MA    +SLE+ L       DL+ V ++LYGK L  +++   A   A + + +LQG+ F A  E  R P+IV VG +QN+I L A+ PV++Q+ ALH RIK I+++A    VNIIC QEAWTMPF FCTREKLPW EFAE   +G TT+F  KLAK H MV++SPILERD    DV+WNTAV+I  +G  LGK+RKNHIPRVGDFNESTYYMEGNLGHPVF T +G+IAVNIC+GRH PLNWL+Y + GA+I+FNPSAT+  LSE+LW IEARNAAIANH FT AINRVGTE FP++FTSGDGK+ H++FG+FYGSSY+ APDGSRT GLSR QDGLL+A++DLNLC+Q+ D W F MT R EMYA++L E V+
Sbjct:    1 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFEAAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEAWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWSIEARNAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDGSRTPGLSRSQDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVK 374
[Close]
BLAST of Beta-ureidopropionase vs. UniProt/SwissProt
Match: sp|Q9UBR1|BUP1_HUMAN (Beta-ureidopropionase OS=Homo sapiens OX=9606 GN=UPB1 PE=1 SV=1)

HSP 1 Score: 496.508 bits (1277), Expect = 1.220e-173
Identity = 232/374 (62.03%), Postives = 287/374 (76.74%), Query Frame = 1 
Query:  160 MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKR--DVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVE 1275
            MA    +SLE+ L       DL+ V ++LYGK L  +++   A   A + + +LQG+ F A  E  R P+IV VG +QN+I L A+ PV++Q+ ALH RIK I+++A    VNIIC QEAWTMPF FCTREKLPW EFAE   +G TT+F  KLAK H MV++SPILERD    DV+WNTAV+I  +G  LGK+RKNHIPRVGDFNESTYYMEGNLGHPVF T +G+IAVNIC+GRH PLNWL+Y + GA+I+FNPSAT+  LSE+LWPIEARNAAIANH FT AINRVGTE FP++FTSGDGK+ H++FG+FYGSSY+ APD SRT GLSR +DGLL+A++DLNLC+Q+ D W F MT R EMYA++L E V+
Sbjct:    1 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFEAAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEAWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVK 374
[Close]
BLAST of Beta-ureidopropionase vs. UniProt/SwissProt
Match: sp|Q03248|BUP1_RAT (Beta-ureidopropionase OS=Rattus norvegicus OX=10116 GN=Upb1 PE=1 SV=1)

HSP 1 Score: 491.115 bits (1263), Expect = 2.002e-171
Identity = 229/374 (61.23%), Postives = 286/374 (76.47%), Query Frame = 1 
Query:  160 MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKRD--VIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVE 1275
            MA    +SLE+ L      +DL  V ++LYGK    +++   A+  A + N +L+G+ F A  E  R PQIVRVG +QN+I L  S PV++Q+ ALH RI++I ++A    VNIIC QEAW MPF FCTREKLPW EFAE   +GLTT+F  KLAK H+MV+ISPILERD+    V+WNTAV+I  +G  +GK+RKNHIPRVGDFNESTYYMEGNLGHPVF T +G+IAVNIC+GRH PLNWL+Y + GA+I+FNPSAT+  LSE++WPIEARNAAIANH FT A+NRVG E +P++FTSGDGK+ H + G+FYGSSY+ APDGSRT GLSR QDGLL+ E++LNLC+QI D W F MT RLEMYA++L E V+
Sbjct:    1 MAGPEWQSLEQCLEKHLPPDDLSQVKRILYGKQTRNLDLPRKALEAASERNFELKGYAFGAAKEQQRCPQIVRVGLVQNRIPLPTSAPVAEQVSALHKRIEEIAEVAAMCGVNIICFQEAWNMPFAFCTREKLPWTEFAESAEDGLTTRFCQKLAKKHNMVVISPILERDRDHGGVLWNTAVVISNSGLVMGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSVNGAEIIFNPSATIGELSESMWPIEARNAAIANHCFTCALNRVGQEHYPNEFTSGDGKKAHHDLGYFYGSSYVAAPDGSRTPGLSRNQDGLLVTELNLNLCQQINDFWTFKMTGRLEMYARELAEAVK 374
[Close]
BLAST of Beta-ureidopropionase vs. UniProt/SwissProt
Match: sp|Q8VC97|BUP1_MOUSE (Beta-ureidopropionase OS=Mus musculus OX=10090 GN=Upb1 PE=1 SV=1)

HSP 1 Score: 490.73 bits (1262), Expect = 3.493e-171
Identity = 229/374 (61.23%), Postives = 285/374 (76.20%), Query Frame = 1 
Query:  160 MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKRD--VIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVE 1275
            MA    +SLE+ L      +DL  V ++LYGK    +++   A+  A + N +L+G+ F A  E  R PQIVRVG +QN+I L  S PV++Q+ ALH  I++I ++A    VNIIC QEAW MPF FCTREKLPW EFAE   +GLTT+F  KLAK H+MV++SPILERD+    V+WNTAV+I  +G  +GK+RKNHIPRVGDFNESTYYMEGNLGHPVF T +G+IAVNIC+GRH PLNWL+Y + GA+I+FNPSAT+  LSE+LWPIEARNAAIANH FT A+NRVG E FP++FTSGDGK+ H + G+FYGSSY+ APDGSRT GLSR QDGLL+ E++LNLC+QI D W F MT RLEMYA++L E V+
Sbjct:    1 MAGPEWQSLEQCLEKHLPPDDLAQVKRILYGKQTRNLDLPREALKAASERNFELKGYAFGAAKEQQRCPQIVRVGLVQNRIPLPTSAPVAEQVSALHKSIEEIAEVAAMCGVNIICFQEAWNMPFAFCTREKLPWTEFAESAEDGLTTRFCQKLAKKHNMVVVSPILERDREHGGVLWNTAVVISNSGLVMGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGELSESLWPIEARNAAIANHCFTCALNRVGQEHFPNEFTSGDGKKAHHDLGYFYGSSYVAAPDGSRTPGLSRNQDGLLVTELNLNLCQQINDFWTFKMTGRLEMYARELAEAVK 374
[Close]
BLAST of Beta-ureidopropionase vs. UniProt/SwissProt
Match: sp|Q8H183|BUP1_ARATH (Beta-ureidopropionase OS=Arabidopsis thaliana OX=3702 GN=PYD3 PE=1 SV=1)

HSP 1 Score: 447.973 bits (1151), Expect = 3.839e-154
Identity = 232/388 (59.79%), Postives = 285/388 (73.45%), Query Frame = 1 
Query:  139 IHSTGSKMAKKSI---ESLEKILLTLGDNEDLEYVTKLLYGK----SLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERD--KRDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVE 1275
            I   G   A+ SI   +SL ++L      E  + V +LL G+    SLE I + E+A   + + + DLQ   F A  E  R P++VRVG IQN I L  + P SDQ   + D++K IID AG   VNI+CLQEAWTMPF FCTRE+  WCEFAE + +G +T+FL +LAK ++MVI+SPILERD    +V+WNTAVII  NGN +GK RKNHIPRVGDFNESTYYMEG+ GHPVF+T++GKIAVNIC+GRH PLNWL +GL GA+IVFNPSATV  LSE +WPIEARNAAIAN YF  +INRVGTEVFP+ FTSGDGK  H +FGHFYGSS+ +APD S T  LSR +DGLLI++MDLNLCRQ KD+WGF MT R E+YA  L ++++
Sbjct:    5 ISENGETSAEGSICGYDSLHQLLSANLKPELYQEVNRLLLGRNCGRSLEQIVLPESAKALSSKHDFDLQAASFSADKEQMRNPRVVRVGLIQNSIALPTTAPFSDQTRGIFDKLKPIIDAAGVAGVNILCLQEAWTMPFAFCTRERR-WCEFAEPV-DGESTKFLQELAKKYNMVIVSPILERDIDHGEVLWNTAVIIGNNGNIIGKHRKNHIPRVGDFNESTYYMEGDTGHPVFETVFGKIAVNICYGRHHPLNWLAFGLNGAEIVFNPSATVGELSEPMWPIEARNAAIANSYFVGSINRVGTEVFPNPFTSGDGKPQHNDFGHFYGSSHFSAPDASCTPSLSRYKDGLLISDMDLNLCRQYKDKWGFRMTARYEVYADLLAKYIK 390
[Close]
BLAST of Beta-ureidopropionase vs. TrEMBL
Match: A0A5E4MJY6 (Carbon-nitrogen hydrolase OS=Cinara cedri OX=506608 GN=CINCED_3A006406 PE=4 SV=1)

HSP 1 Score: 512.686 bits (1319), Expect = 8.271e-178
Identity = 238/365 (65.21%), Postives = 290/365 (79.45%), Query Frame = 1 
Query:  178 ESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKRDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFV 1272
            +SLE  L      E+L +V ++LYGK LE + + E   N+ +  N++++G++F +  E  R  +IVRVG IQNQIVL  + P+ +Q  A++ ++ +II LA K  VNIICLQEAW+MPF FCTREK PWC+FAE +  G +T FL +  K H+MVIISPILERD+RD+IWNTAV+ID  GN +GK RKNHIPRVGDFNESTYYMEGN GHPVF+T +G+IA+NIC+GRH PLNWL++GL GA+IVFNPSAT+DGLSETLW IE+R AA+AN YF+ AINRVGTE+FP +FTSGDGK  HKEFGHFYGSSYITAPDGSRT GLSR Q GLLI+EMDLNLCRQIKD WGF MTQRL++YAK L   V
Sbjct:    3 QSLETCLEKYVPPEELGHVKRILYGKQLEELQLPELCTNNKE--NVEVKGYKFDSLVEELREKRIVRVGLIQNQIVLPTTAPLVEQRNAIYKKVGQIISLAAKANVNIICLQEAWSMPFAFCTREKFPWCQFAESVENGPSTTFLKEFCKQHNMVIISPILERDERDIIWNTAVVIDNLGNVIGKHRKNHIPRVGDFNESTYYMEGNTGHPVFETAFGRIAINICYGRHHPLNWLMFGLNGAEIVFNPSATIDGLSETLWGIESRTAAVANSYFSCAINRVGTEIFPAEFTSGDGKPAHKEFGHFYGSSYITAPDGSRTPGLSRTQSGLLISEMDLNLCRQIKDHWGFQMTQRLDLYAKSLDTIV 365
[Close]
BLAST of Beta-ureidopropionase vs. TrEMBL
Match: A0A0A9Z1K6 (Beta-ureidopropionase OS=Lygus hesperus OX=30085 GN=UPB1_0 PE=4 SV=1)

HSP 1 Score: 511.531 bits (1316), Expect = 5.276e-177
Identity = 247/373 (66.22%), Postives = 291/373 (78.02%), Query Frame = 1 
Query:  160 MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDK-RDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVE 1275
            MA    ESLE +L    +  DLE V +++YGKSLE I +   AV  A++ +IDLQG+   A  E TR P+IVR+GAIQN+IVL  SEPV DQ  ALH RI++I+ +A    VNIICLQEAWTMPF FCTRE+LPW EFAE    G TT FL KLAK+H+MVIISPILERD     IWNTAV+ID  G+ LGK RKNHIPRVGDFNESTYY EGN GHPVF T +G+IA+NIC+GRH PLNWL++GL GA+IVFNPSATV GLSE LW IEARNAAIANHYFTVAINRVG EVFP +FTSGDGK  H+ FG FYGS+Y+TAPDG+RT GLSR QDGLLI E+DLN+C+Q++D W F MTQRL +YA++L +  +
Sbjct:    1 MAGVQTESLEALLSRNLEVGDLEEVQRIIYGKSLEKIAMPA-AVEAAEKADIDLQGYVMRAPREQTRSPRIVRIGAIQNKIVLATSEPVDDQRKALHSRIEEIVRIAAVASVNIICLQEAWTMPFAFCTRERLPWTEFAESAENGPTTLFLKKLAKSHNMVIISPILERDDVLGTIWNTAVVIDNAGSVLGKHRKNHIPRVGDFNESTYYFEGNTGHPVFQTDFGRIAINICYGRHHPLNWLMFGLNGAEIVFNPSATVAGLSEHLWGIEARNAAIANHYFTVAINRVGEEVFPREFTSGDGKPAHRNFGWFYGSTYLTAPDGTRTPGLSRTQDGLLITELDLNMCQQVQDNWNFRMTQRLPLYAEQLTKVCQ 372
[Close]
BLAST of Beta-ureidopropionase vs. TrEMBL
Match: A0A0K8T7L1 (CN hydrolase domain-containing protein OS=Lygus hesperus OX=30085 PE=4 SV=1)

HSP 1 Score: 510.76 bits (1314), Expect = 1.038e-176
Identity = 247/373 (66.22%), Postives = 290/373 (77.75%), Query Frame = 1 
Query:  160 MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDK-RDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVE 1275
            MA    ESLE +L    +  DLE V +++YGKSLE I +   AV  A++ +IDLQG+   A  E TR P+IVR+GAIQN+IVL  SEPV DQ  ALH RI++I+ +A    VNIICLQEAWTMPF FCTRE LPW EFAE    G TT FL KLAK+H+MVIISPILERD     IWNTAV+ID  G+ LGK RKNHIPRVGDFNESTYY EGN GHPVF T +G+IA+NIC+GRH PLNWL++GL GA+IVFNPSATV GLSE LW IEARNAAIANHYFTVAINRVG EVFP +FTSGDGK  H+ FG FYGS+Y+TAPDG+RT GLSR QDGLLI E+DLN+C+Q++D W F MTQRL +YA++L +  +
Sbjct:    1 MAGVQTESLEALLSRNLEVGDLEEVQRIIYGKSLEKIAMPA-AVEAAEKADIDLQGYVMRAPREQTRSPRIVRIGAIQNKIVLATSEPVDDQRKALHSRIEEIVRIAAVASVNIICLQEAWTMPFAFCTRESLPWTEFAESAENGPTTLFLKKLAKSHNMVIISPILERDDVLGTIWNTAVVIDNAGSVLGKHRKNHIPRVGDFNESTYYFEGNTGHPVFQTDFGRIAINICYGRHHPLNWLMFGLNGAEIVFNPSATVAGLSEHLWGIEARNAAIANHYFTVAINRVGEEVFPREFTSGDGKPAHRNFGWFYGSTYLTAPDGTRTPGLSRTQDGLLITELDLNMCQQVQDNWNFRMTQRLPLYAEQLTKVCQ 372
[Close]
BLAST of Beta-ureidopropionase vs. TrEMBL
Match: A0A0A9Z3V8 (Beta-ureidopropionase OS=Lygus hesperus OX=30085 GN=UPB1_1 PE=4 SV=1)

HSP 1 Score: 514.227 bits (1323), Expect = 4.605e-176
Identity = 249/377 (66.05%), Postives = 294/377 (77.98%), Query Frame = 1 
Query:  154 SKMAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKRDV---IWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVE 1275
            + MA    ESLE +L    +  DLE V +++YGKSLE I +   AV  A++ +IDLQG+   A  E TR P+IVR+GAIQN+IVL  SEPV DQ  ALH RI++I+ +A    VNIICLQEAWTMPF FCTRE+LPW EFAE    G TT FL KLAK+H+MVIISPILERD  DV   IWNTAV+ID  G+ LGK RKNHIPRVGDFNESTYY EGN GHPVF T +G+IA+NIC+GRH PLNWL++GL GA+IVFNPSATV GLSE LW IEARNAAIANHYFTVAINRVG EVFP +FTSGDGK  H+ FG FYGS+Y+TAPDG+RT GLSR QDGLLI E+DLN+C+Q++D W F MTQRL +YA++L +  +
Sbjct:  131 TNMAGVQTESLEALLSRNLEVGDLEEVQRIIYGKSLEKIAMPA-AVEAAEKADIDLQGYVMRAPREQTRSPRIVRIGAIQNKIVLATSEPVDDQRKALHSRIEEIVRIAAVASVNIICLQEAWTMPFAFCTRERLPWTEFAESAENGPTTLFLKKLAKSHNMVIISPILERD--DVLGTIWNTAVVIDNAGSVLGKHRKNHIPRVGDFNESTYYFEGNTGHPVFQTDFGRIAINICYGRHHPLNWLMFGLNGAEIVFNPSATVAGLSEHLWGIEARNAAIANHYFTVAINRVGEEVFPREFTSGDGKPAHRNFGWFYGSTYLTAPDGTRTPGLSRTQDGLLITELDLNMCQQVQDNWNFRMTQRLPLYAEQLTKVCQ 504
[Close]
BLAST of Beta-ureidopropionase vs. TrEMBL
Match: T2M4E1 (Beta-ureidopropionase (Fragment) OS=Hydra vulgaris OX=6087 GN=UPB1 PE=2 SV=1)

HSP 1 Score: 506.138 bits (1302), Expect = 5.060e-175
Identity = 237/372 (63.71%), Postives = 292/372 (78.49%), Query Frame = 1 
Query:  157 KMAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDK--RDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQE 1266
            K   K ++SL+ IL     +EDL+ V +LLYG+ +  I++ E++V+ A   N ++ G++  A  E  R P+IVRV A+QN+IVL    P+ +QI A+H+R K  I+ A   +VNI+C QEAWTMPF FCTREK PWC+FAE    G TT FL  LAK H+MVIISPILERD+  +DV+WNTAV+I   G++LGKSRKNHIPRVGDFNESTYYME  LGHPVF+T++G+IAVNICFGRH PLNWL +GL GA+IVFNPSATV  LSE +WPIEAR AAIAN YFTVAINRVG E FP++FTSGDGK  HK+FGHFYGSSYI+AP+GSRT GLSR+ DG++IAE+DLNLCRQ+KD+WGF MTQRL +YAK L +
Sbjct:    1 KKMTKEVKSLDDILSRNLKDEDLQEVQRLLYGEPVVKISLTEDSVSIAADNNFEICGYKMTALQEEERPPRIVRVAAVQNKIVLPTDAPILEQIKAIHERAKLFIEAAASNQVNILCFQEAWTMPFAFCTREKHPWCQFAESAENGATTIFLHHLAKKHNMVIISPILERDEAHQDVLWNTAVVISNKGSYLGKSRKNHIPRVGDFNESTYYMESELGHPVFETLFGRIAVNICFGRHHPLNWLSFGLNGAEIVFNPSATVGALSEPMWPIEARCAAIANSYFTVAINRVGKEYFPNEFTSGDGKPAHKDFGHFYGSSYISAPNGSRTPGLSRINDGIIIAELDLNLCRQVKDKWGFQMTQRLPLYAKFLTD 372
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Cavefish
Match: upb1 (beta-ureidopropionase 1 [Source:NCBI gene;Acc:103031480])

HSP 1 Score: 468.389 bits (1204), Expect = 1.686e-163
Identity = 217/374 (58.02%), Postives = 280/374 (74.87%), Query Frame = 1 
Query:  160 MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKRD--VIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVE 1275
            M+K + +S+E  L       +L+ V ++LYGK L  + + ++A+  A + + DL G+ F A+ E  R  + VRVG IQN+IVL    PV +QI ALH R+ +++D+A    VNI+C QEAWTMPF FCTRE+ PW EFAE    G TT+F  +LAK ++MV++SPILERD+     +WNTAV++   GN LGKSRKNHIPRVGDFNES+YYMEGN  H VF+T YGKI VNIC+GRH PLNWL+Y + GA+I+FNPSATV  LSE +WPIEARNAAIANH FT AINRVGTE F ++FTSGDGK+ H EFGHFYGSSY+ APDG+R+ GLSR++DGLL+AE+DLNL RQ+ D+W F MT R +MYA ++ + ++
Sbjct:    1 MSKSTFDSVEMSLEANIPATELKEVKRILYGKELRKLVLPQSALVAALERDFDLHGYVFEAEPEQIRAARTVRVGLIQNKIVLPTDAPVLEQITALHKRVGEMVDVAAACGVNIVCFQEAWTMPFAFCTRERAPWTEFAESAEGGFTTRFCKELAKKYNMVVVSPILERDELHGGTLWNTAVVVSNTGNVLGKSRKNHIPRVGDFNESSYYMEGNTRHRVFNTQYGKIGVNICYGRHHPLNWLMYSMNGAEIIFNPSATVGELSEPMWPIEARNAAIANHCFTCAINRVGTEYFKNEFTSGDGKKAHHEFGHFYGSSYVAAPDGTRSPGLSRIRDGLLVAELDLNLNRQVADKWNFKMTGRYDMYADEITKAIQ 374
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Cavefish
Match: nit1 (nitrilase 1 [Source:NCBI gene;Acc:103037987])

HSP 1 Score: 56.225 bits (134), Expect = 2.887e-8
Identity = 59/238 (24.79%), Postives = 105/238 (44.12%), Query Frame = 1 
Query:  376 RVGAIQNQIVLGASEPVSD--QILALHDR------IKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSM-VIISPILER------DKRDVIWNTAVIIDQNGNFLGKSRKNHI------PRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGT 1026
            R  A +NQ+ + +S PV+   Q+ +  D+       ++++  A + + +++ L E     F +    +    + +E + +G T     KLAK  ++ + +    ER      D+R  I+N+ VII++ G  +   RK H+       R     ES + + G    P  +T  GK+ + IC+    P   L    +GA+I+  PSA         W +  R  AI    F +A  +VG 
Sbjct:   24 RSQAGRNQLRMASSHPVAAVCQMTSTPDKEANFTTCERLVKQAKEGRASMVFLPEG----FDYIGSSREETLQLSESL-QGDTISRYTKLAKELNVWLSLGGFHERGHDWENDRR--IYNSHVIINEQGGIVSVYRKGHLFDVELANRGVSLKESAFTIPGPSLVPPVETPVGKVGLGICYDLRFPELSLALQRQGAEILTYPSAFTVATGAAHWEVLLRARAIETQCFVLAAAQVGA 254
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008167.1 (pep scaffold:Pmarinus_7.0:GL477981:1516:9010:-1 gene:ENSPMAG00000007381.1 transcript:ENSPMAT00000008167.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 207.608 bits (527), Expect = 8.681e-65
Identity = 100/209 (47.85%), Postives = 142/209 (67.94%), Query Frame = 1 
Query:  160 MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDK--RDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNEST 780
            MA  +I+SL++ L      ++L  V ++LYG+  + +++   A+  A+    +L+ F   A  E  R P++VRVG +QN+IV   + PV+ Q+ ALH R+  +++ A    VNI+C QEAWTMPF FCTRE+LPW EFAE   +G TT F  +LA+ +++V++SPILERD+  RD IWNTAV+I  +G  LGK+RKNHIPRVGDFNE T
Sbjct:    1 MADAAIKSLDETLEKYIPAQELAEVNRILYGRRPKPLDVPVAALRLAEVGGFELRAFTIGAAPEQLRPPRLVRVGLMQNRIVEPTTAPVAQQVSALHKRLASMVETAALCGVNIVCFQEAWTMPFAFCTRERLPWTEFAESAEDGPTTLFCQELARRYNVVVVSPILERDEVHRDTIWNTAVVISNSGAVLGKTRKNHIPRVGDFNEVT 209
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006563.1 (pep scaffold:Pmarinus_7.0:GL482671:2818:12612:-1 gene:ENSPMAG00000005923.1 transcript:ENSPMAT00000006563.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 171.014 bits (432), Expect = 5.980e-52
Identity = 82/112 (73.21%), Postives = 91/112 (81.25%), Query Frame = 1 
Query:  943 SETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGF-SMTQRLEMYAKKLQEFVE 1275
            SE LW IEARNAAIANHYFT AINRVGTE FP+ FTSGDGK+ H EFGHFYGSSY+ APDGSRT GL R+ DGLLIAE+DLNL RQ+ D WGF  MT R EMYA++L   V+
Sbjct:    5 SEPLWAIEARNAAIANHYFTCAINRVGTECFPNAFTSGDGKEAHCEFGHFYGSSYVAAPDGSRTPGLGRMNDGLLIAELDLNLNRQVSDHWGFRKMTGRYEMYAEELARSVK 116
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Yeast
Match: NIT3 (Nit protein; one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member [Source:SGD;Acc:S000004343])

HSP 1 Score: 68.1662 bits (165), Expect = 3.295e-13
Identity = 76/313 (24.28%), Postives = 131/313 (41.85%), Query Frame = 1 
Query:  346 SESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLK--VNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIIS-PILERD-KRDVIWNTAVIIDQNGNFLGKSRKNH-----IPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDG--LLIAEMDLNLCRQIKDEWGFSMTQRLEMYA 1251
            S S  + Q ++V  +Q    L  S P  D++  L  R    I+ A K +    ++ L E +  P+   T +   + E         + QFL  LA    ++++   I E D K D I+NT++I +++G  + K RK H     IP    F+ES     G     + DT YGK  V IC+    P   ++   +GA  +  PSA         W + AR+ A+ N  + +  +                +     + H YG S +  P G   K ++   +G  ++ AE+D  +    +     +  +R ++Y+
Sbjct:    2 SASKILSQKIKVALVQ----LSGSSP--DKMANLQ-RAATFIERAMKEQPDTKLVVLPECFNSPYS--TDQFRKYSEVINPKEPSTSVQFLSNLANKFKIILVGGTIPELDPKTDKIYNTSIIFNEDGKLIDKHRKVHLFDVDIPNGISFHESETLSPGEKSTTI-DTKYGKFGVGICYDMRFPELAMLSARKGAFAMIYPSAFNTVTGPLHWHLLARSRAVDNQVYVMLCS--------------PARNLQSSY-HAYGHSIVVDPRG---KIVAEAGEGEEIIYAELDPEVIESFRQAVPLTKQRRFDVYS 286
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Nematostella
Match: EDO37352 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG03])

HSP 1 Score: 356.295 bits (913), Expect = 2.908e-120
Identity = 183/369 (49.59%), Postives = 240/369 (65.04%), Query Frame = 1 
Query:  178 ESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERD--KRDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVEK 1278
            ESL K L      EDL+ V ++LYG  +  +++   AV+ A +L+ +L G++  A +E  R P++VR+GA+QN+IV   + P++ Q   LH+R+K I+  A   KVN+IC QE WTMPF FCTREK PW EFAE   +G T +   + AK ++MVI+SPILERD   ++++WNTAVII   G  +GK+RKNHIPRVGDFNESTYYMEG++GH VF T +         GR   ++W +  L+G+  +         L E LW IEARNAAIAN YFTV INRVGT     +        P         SSY+ AP+GSRT GLSR +DGLL+ E+DLNLCRQ+KD+WGF MT RLEMYAK L E V++
Sbjct:    6 ESLNKTLEKNLPAEDLKEVKRILYGNPVSDLSLPAAAVSVAAELDFELAGYKIDAAAEELRQPRLVRIGAVQNKIVEPTNMPIAKQREGLHNRMKDIVKAAALSKVNVICFQECWTMPFAFCTREKQPWTEFAESAEDGPTVRLCQEWAKRYNMVIVSPILERDHTHQEILWNTAVIISNTGEVIGKTRKNHIPRVGDFNESTYYMEGDMGHQVFQTQFDT-------GR---ISWFLVSLQGSHYIL----VALHLCEPLWSIEARNAAIANSYFTVPINRVGTASILEE------NNPR--------SSYVAAPNGSRTPGLSRTRDGLLVTEVDLNLCRQVKDKWGFQMTSRLEMYAKSLSEAVQR 346
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Nematostella
Match: EDO30709 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T002])

HSP 1 Score: 70.0922 bits (170), Expect = 1.869e-13
Identity = 71/300 (23.67%), Postives = 125/300 (41.67%), Query Frame = 1 
Query:  370 IVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAK-THSMVIISPILERDKRDVIWNTAVIIDQNGNFLGKSRKNH-----IPRVGDFNESTYYMEG-NLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMY 1248
            + R+G +Q    L  +      +    ++IK+ +    K    I+ L E +  P+G        + ++AE IP G ++  L ++AK T + ++   I ER     ++NT++  D +GN +GK RK H     +P    F ES     G NL   + DT Y KI + IC+    P    +Y  +G  ++  P A         W +  R  A+ N  +   I+            + D    +  +GH    S +  P G         +  +L AE+DL    +++ +      +R ++Y
Sbjct:    7 VFRIGLVQ----LAVTANKLQNLQRAREKIKEAVAAGAK----IVALPECFNSPYGTQY-----FKDYAEEIP-GESSNMLAEVAKETGAYIVGGSIPERASNGKLYNTSLSYDPSGNLMGKHRKIHLFDIDVPGKIRFQESEVLSPGENLT--ILDTEYCKIGIGICYDMRFPELAQLYAKKGCHLLLYPGAFNMTTGPAHWELLTRARALDNQLYVATIS-----------PARDDNATYIAWGH----STVVNPWGKIVSKADHTEQ-ILYAEIDLKYLNEVRSQIPVQFQKRDDVY 274
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Nematostella
Match: EDO27394 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T9D3])

HSP 1 Score: 56.9954 bits (136), Expect = 9.095e-10
Identity = 41/127 (32.28%), Postives = 64/127 (50.39%), Query Frame = 1 
Query:  568 EFAERIPEGLTTQFLCKLAK-THSMVIISPILERDKRDVIWNTAVIIDQNGNFLGKSRKNH-----IPRVGDFNESTYYMEG-NLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSA 927
            ++AE IP G ++  L ++AK T + ++   I ER     ++NT++  D +GN +GK RK H     +P    F ES     G NL   + DT Y KI + IC+    P    +Y  +G  ++  P A
Sbjct:   14 DYAEEIP-GESSNMLAEVAKETGAYIVGGSIPERASNRKLYNTSLSYDPSGNLMGKHRKIHLFDIDVPGKIRFQESEVLSPGENL--TILDTEYCKIGIGICYDMRFPELAQLYAKKGCHLLLYPGA 137
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Nematostella
Match: EDO47206 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMU0])

HSP 1 Score: 56.225 bits (134), Expect = 9.304e-9
Identity = 60/251 (23.90%), Postives = 103/251 (41.04%), Query Frame = 1 
Query:  532 FGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTH----SMVIISPILERDKRDVIWNTAVIIDQNGNFLGKSRKNHIPRVG-----DFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQD--GLLIAEMDLNLCRQIKDEWGFSMTQRLEMYA 1251
            F F  ++K    E AE + +G     +CKLA+ +    S+         + R V+ N  V+ID  G       K H+  V         ES +   G+   P   T  GK+ + IC+    P   ++   +GA I+  PSA         W +  R+ AI    + VA  + G           +G++        YG S +  P G+    +++ QD  GL +AE+D    ++++        +R+++Y 
Sbjct:   48 FDFLMKDKEKILELAEHL-DGPRISKMCKLAEENGVWLSLGGFHCKHPSETRRVL-NCHVVIDNKGRIAASYNKTHLFDVNIEGGPCLKESAFIAHGDRIVPPVSTPVGKLGLGICYDLRFPEFSMILARQGADILSFPSAFTFHTGSAHWEVLLRSRAIETQCYVVAAAQCGKLY--------EGREA-------YGHSMVVDPWGTV---VAQCQDGIGLCMAEIDHQYIQKVRSGMPILSHRRVDLYG 278
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Medaka
Match: upb1 (beta-ureidopropionase 1 [Source:NCBI gene;Acc:101160078])

HSP 1 Score: 467.233 bits (1201), Expect = 3.748e-163
Identity = 222/372 (59.68%), Postives = 274/372 (73.66%), Query Frame = 1 
Query:  160 MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDK-RDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFV 1272
            M+    ESLEK L +     +L  V ++LYGK    +++   AV  A + N +L+ F+F A  E  R P+  RVG +Q++IVL    PV +QI A+H R+ +I+++A    VNIIC QE WTMPF FCTREK PW EFAE   EG TT+F  +LAK ++MVIISPILER++    +WN+AV+I  +GN LGKSRKNHIPRVGDFNESTYYMEG+ GH VF T +G+IAVNIC+GRH PLNW +Y + GA+I+FNPSATV  LSE +WPIEARNAAIANH FT AINRVGTE F ++FTSGDG++ H +FGHFYGSSY+ APDGSRT GLSR QDGLL+ EMDLNL RQ+ D+W F MT R   YA+KL E V
Sbjct:    1 MSSCEFESLEKSLESHLPEAELVEVKRILYGKETLKLDLPAFAVEAASERNFELKAFKFDALQEQLRPPRRTRVGLVQHKIVLPTDAPVLEQINAIHSRVGEIVEVAAMCGVNIICFQETWTMPFAFCTREKEPWTEFAESAEEGNTTRFCQELAKKYNMVIISPILEREELHSKLWNSAVVISNSGNVLGKSRKNHIPRVGDFNESTYYMEGDTGHTVFQTQFGRIAVNICYGRHHPLNWFMYSMNGAEIIFNPSATVGALSEPMWPIEARNAAIANHCFTCAINRVGTEHFKNEFTSGDGRKAHHDFGHFYGSSYVAAPDGSRTPGLSRTQDGLLVVEMDLNLNRQVSDKWSFKMTGRYAEYAEKLTEAV 372
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Medaka
Match: nit2 (nitrilase family member 2 [Source:NCBI gene;Acc:101170666])

HSP 1 Score: 64.6994 bits (156), Expect = 3.919e-11
Identity = 65/307 (21.17%), Postives = 125/307 (40.72%), Query Frame = 1 
Query:  346 SESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKRDVIWNTAVIIDQNGNFLGKSRKNH-----IPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYA 1251
            + + RI    R+  +Q Q+    ++ +S        R ++++  A      ++ L E +  P+G        + ++AE+IP G +TQ L + AK + + ++   +  +    ++NT  +    G  + K RK H     +P    F ES     GN     FDT + K+ V IC+         VY  EG Q++  P A         W +  R  A+ N  +    +            + D    +  +GH    S +  P G      +  ++ ++ A++DL     I+ +   +  +R ++Y+
Sbjct:    2 TAAARIMSKFRLAVVQLQVTSVKADNLS--------RARRLVLQAAGQGSKVVLLPECFNSPYGTSF-----FSDYAEKIP-GESTQMLSEAAKENQVYLVGGSIPEEDGGKLYNTCAVFGPGGEMILKHRKIHLFDINVPGKICFQESETLSPGN-SLSTFDTPFCKVGVGICYDMRFAELAQVYSREGCQLLVYPGAFNMTTGPAHWELLQRGRAVDNQVYVATAS-----------PARDEAASYVAWGH----STVVNPWG-EVISKAGAEETVIYADIDLQYLSDIRRQIPITAQRRDDLYS 277
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Medaka
Match: nit2 (nitrilase family member 2 [Source:NCBI gene;Acc:101170666])

HSP 1 Score: 63.1586 bits (152), Expect = 9.569e-11
Identity = 47/188 (25.00%), Postives = 80/188 (42.55%), Query Frame = 1 
Query:  451 DRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKRDVIWNTAVIIDQNGNFLGKSRKNH-----IPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYF 999
             R ++++  A      ++ L E +  P+G        + ++AE+IP G +TQ L + AK + + ++   +  +    ++NT  +    G  + K RK H     +P    F ES     GN     FDT + K+ V IC+         VY  EG Q++  P A         W +  R  A+ N  +
Sbjct:   22 SRARRLVLQAAGQGSKVVLLPECFNSPYGTSF-----FSDYAEKIP-GESTQMLSEAAKENQVYLVGGSIPEEDGGKLYNTCAVFGPGGEMILKHRKIHLFDINVPGKICFQESETLSPGN-SLSTFDTPFCKVGVGICYDMRFAELAQVYSREGCQLLVYPGAFNMTTGPAHWELLQRGRAVDNQVY 202
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Medaka
Match: nit1 (nitrilase 1 [Source:NCBI gene;Acc:101174868])

HSP 1 Score: 55.0694 bits (131), Expect = 6.656e-8
Identity = 56/212 (26.42%), Postives = 87/212 (41.04%), Query Frame = 1 
Query:  652 PILERDKRDVIWNTAVIIDQNGNFLGKSRKNHI-----PRVG-DFNESTYYMEG-NLGHPVFDTIYGKIAVNICFG-RHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQ 1263
            P  ER+KR  I+N+ +II+  G+ +   RK+H+     P  G    ES + + G +L  PV  T  GK+ + IC+  R   L+ L     GA+I+  PSA         W +  R  AI    F +A  +VG                H E    YG S    P G            +++ E+DL+  R+ +        +R   +   L+
Sbjct:  122 PEWEREKR--IYNSHIIINNKGDIVSVYRKSHLFDVKLPEKGISLMESDFTLPGPSLVSPV-QTPIGKVGLGICYDLRFSELS-LALQRSGAEILTYPSAFTVATGAAHWEVLLRARAIETQCFVLAAAQVGQ---------------HHEKRASYGHSLAVDPWGEVLADCGGESPAVVLVEVDLDKVRRTRKNMPVQQHRRETAFYHSLE 314
[Close]
BLAST of Beta-ureidopropionase vs. Ensembl Medaka
Match: nit1 (nitrilase 1 [Source:NCBI gene;Acc:101174868])

HSP 1 Score: 54.6842 bits (130), Expect = 6.969e-8
Identity = 56/212 (26.42%), Postives = 87/212 (41.04%), Query Frame = 1 
Query:  652 PILERDKRDVIWNTAVIIDQNGNFLGKSRKNHI-----PRVG-DFNESTYYMEG-NLGHPVFDTIYGKIAVNICFG-RHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQ 1263
            P  ER+KR  I+N+ +II+  G+ +   RK+H+     P  G    ES + + G +L  PV  T  GK+ + IC+  R   L+ L     GA+I+  PSA         W +  R  AI    F +A  +VG                H E    YG S    P G            +++ E+DL+  R+ +        +R   +   L+
Sbjct:  108 PEWEREKR--IYNSHIIINNKGDIVSVYRKSHLFDVKLPEKGISLMESDFTLPGPSLVSPV-QTPIGKVGLGICYDLRFSELS-LALQRSGAEILTYPSAFTVATGAAHWEVLLRARAIETQCFVLAAAQVGQ---------------HHEKRASYGHSLAVDPWGEVLADCGGESPAVVLVEVDLDKVRRTRKNMPVQQHRRETAFYHSLE 300
[Close]
BLAST of Beta-ureidopropionase vs. Planmine SMEST
Match: SMESG000060425.1 (SMESG000060425.1)

HSP 1 Score: 781.171 bits (2016), Expect = 0.000e+0
Identity = 375/376 (99.73%), Postives = 375/376 (99.73%), Query Frame = 1 
Query:  160 MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKRDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVEKFEN 1287
            MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLG SEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKRDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVEKFEN
Sbjct:    1 MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQLNIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGTSEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKRDVIWNTAVIIDQNGNFLGKSRKNHIPRVGDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGDGKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKDEWGFSMTQRLEMYAKKLQEFVEKFEN 376
[Close]
BLAST of Beta-ureidopropionase vs. Planmine SMEST
Match: SMESG000071423.1 (SMESG000071423.1)

HSP 1 Score: 61.6178 bits (148), Expect = 2.956e-10
Identity = 57/220 (25.91%), Postives = 90/220 (40.91%), Query Frame = 1 
Query:  370 IVRVGAIQNQIVLGASEPVSDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKRDVIWNTAVIIDQNGNFLGKSRKNH-----IPRVGDFNESTYYMEGN----LGHPVFDTIYGKIAVNICFG-RHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYF 999
            +++V  IQ  +    S    D +L    +IK   D   KL    ICL E +  P+G    +  P  E+ E IP   T++ L  +AK HS+ ++   +   +   I+NT ++ + NG  +G   K H     IP    F EST    GN       PV +     + + IC+  R   L  +        ++  P A         W + AR  A+ N  +
Sbjct:    1 MLKVALIQMMVTANKS----DNLLKACSKIKLAADKGAKL----ICLPECFNCPYGI---KYFP--EYCENIPNEKTSKSLSDIAKEHSIWLVGGSIPESREGKIYNTCLVFNPNGELVGTYSKIHLFDIKIPGKMVFQESTTLTAGNKLFSFDIPVDNDKKVTVGLGICYDVRFAELAHIYTRKHNCNLLLYPGAFNMTTGPLHWELLARFRAMDNQCY 207
[Close]
BLAST of Beta-ureidopropionase vs. Planmine SMEST
Match: SMESG000071423.1 (SMESG000071423.1)

HSP 1 Score: 61.2326 bits (147), Expect = 3.479e-10
Identity = 54/201 (26.87%), Postives = 83/201 (41.29%), Query Frame = 1 
Query:  427 SDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKRDVIWNTAVIIDQNGNFLGKSRKNH-----IPRVGDFNESTYYMEGN----LGHPVFDTIYGKIAVNICFG-RHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYF 999
            SD +L    +IK   D   KL    ICL E +  P+G    +  P  E+ E IP   T++ L  +AK HS+ ++   +   +   I+NT ++ + NG  +G   K H     IP    F EST    GN       PV +     + + IC+  R   L  +        ++  P A         W + AR  A+ N  +
Sbjct:    7 SDNLLKACSKIKLAADKGAKL----ICLPECFNCPYGI---KYFP--EYCENIPNEKTSKSLSDIAKEHSIWLVGGSIPESREGKIYNTCLVFNPNGELVGTYSKIHLFDIKIPGKMVFQESTTLTAGNKLFSFDIPVDNDKKVTVGLGICYDVRFAELAHIYTRKHNCNLLLYPGAFNMTTGPLHWELLARFRAMDNQCY 198
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BLAST of Beta-ureidopropionase vs. Planmine SMEST
Match: SMESG000071423.1 (SMESG000071423.1)

HSP 1 Score: 61.2326 bits (147), Expect = 3.644e-10
Identity = 54/201 (26.87%), Postives = 83/201 (41.29%), Query Frame = 1 
Query:  427 SDQILALHDRIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKRDVIWNTAVIIDQNGNFLGKSRKNH-----IPRVGDFNESTYYMEGN----LGHPVFDTIYGKIAVNICFG-RHQPLNWLVYGLEGAQIVFNPSATVDGLSETLWPIEARNAAIANHYF 999
            SD +L    +IK   D   KL    ICL E +  P+G    +  P  E+ E IP   T++ L  +AK HS+ ++   +   +   I+NT ++ + NG  +G   K H     IP    F EST    GN       PV +     + + IC+  R   L  +        ++  P A         W + AR  A+ N  +
Sbjct:    8 SDNLLKACSKIKLAADKGAKL----ICLPECFNCPYGI---KYFP--EYCENIPNEKTSKSLSDIAKEHSIWLVGGSIPESREGKIYNTCLVFNPNGELVGTYSKIHLFDIKIPGKMVFQESTTLTAGNKLFSFDIPVDNDKKVTVGLGICYDVRFAELAHIYTRKHNCNLLLYPGAFNMTTGPLHWELLARFRAMDNQCY 199
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BLAST of Beta-ureidopropionase vs. Planmine SMEST
Match: SMESG000071424.1 (SMESG000071424.1)

HSP 1 Score: 55.0694 bits (131), Expect = 5.346e-9
Identity = 35/112 (31.25%), Postives = 60/112 (53.57%), Query Frame = 1 
Query:  454 RIKKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQFLCKLAKTHSMVIISPILERDKRDVIWNTAVIIDQNGNFLGKSRKNHI-----PRVGDFNE 774
            +++  I LA K  V ++CL E +  PFG    E L   + +E IP G T Q L K++K  ++ I+   +   + + I+N+++I + NG  +G   K H+     PR+ DF +
Sbjct:   21 QVESKIKLATKSGVKLVCLPEYFNCPFG---SEDL--LKQSENIPNGETYQMLSKVSKECAIWIVGGSIPELRANKIYNSSMIFNPNGQLIGTYSKMHLFDSNRPRMPDFRK 127
The following BLAST results are available for this feature:
BLAST of Beta-ureidopropionase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
UPB12.540e-17462.03beta-ureidopropionase 1 [Source:HGNC Symbol;Acc:HG... [more]
UPB17.517e-2643.09beta-ureidopropionase 1 [Source:HGNC Symbol;Acc:HG... [more]
NIT12.961e-1027.50nitrilase 1 [Source:HGNC Symbol;Acc:HGNC:7828][more]
NIT13.387e-1027.50nitrilase 1 [Source:HGNC Symbol;Acc:HGNC:7828][more]
NIT14.198e-1027.50nitrilase 1 [Source:HGNC Symbol;Acc:HGNC:7828][more]
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BLAST of Beta-ureidopropionase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
upb-11.616e-16460.27UreidoPropionase Beta [Source:UniProtKB/TrEMBL;Ac... [more]
nft-11.455e-924.47Nitrilase and fragile histidine triad fusion prote... [more]
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BLAST of Beta-ureidopropionase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
pyd32.427e-16160.39gene:FBgn0037513 transcript:FBtr0081780[more]
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BLAST of Beta-ureidopropionase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
upb12.321e-17260.96ureidopropionase, beta [Source:ZFIN;Acc:ZDB-GENE-0... [more]
upb12.321e-17260.96ureidopropionase, beta [Source:ZFIN;Acc:ZDB-GENE-0... [more]
upb11.255e-8471.01ureidopropionase, beta [Source:ZFIN;Acc:ZDB-GENE-0... [more]
nit21.384e-822.51nitrilase family, member 2 [Source:NCBI gene;Acc:4... [more]
nit12.179e-623.40nitrilase 1 [Source:ZFIN;Acc:ZDB-GENE-040912-65][more]
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BLAST of Beta-ureidopropionase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
upb17.722e-17364.67ureidopropionase, beta [Source:NCBI gene;Acc:10014... [more]
upb11.346e-16765.67ureidopropionase, beta [Source:NCBI gene;Acc:10014... [more]
upb16.006e-16765.77ureidopropionase, beta [Source:NCBI gene;Acc:10014... [more]
upb17.842e-16765.77ureidopropionase, beta [Source:NCBI gene;Acc:10014... [more]
upb19.369e-16765.28ureidopropionase, beta [Source:NCBI gene;Acc:10014... [more]
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BLAST of Beta-ureidopropionase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Upb14.994e-17261.23ureidopropionase, beta [Source:MGI Symbol;Acc:MGI:... [more]
Upb19.135e-3350.00ureidopropionase, beta [Source:MGI Symbol;Acc:MGI:... [more]
Nit28.629e-1323.33nitrilase family, member 2 [Source:MGI Symbol;Acc:... [more]
Nit14.269e-1124.88nitrilase 1 [Source:MGI Symbol;Acc:MGI:1350916][more]
Nit14.587e-1124.88nitrilase 1 [Source:MGI Symbol;Acc:MGI:1350916][more]
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BLAST of Beta-ureidopropionase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5RBM6|BUP1_PONAB7.713e-17462.30Beta-ureidopropionase OS=Pongo abelii OX=9601 GN=U... [more]
sp|Q9UBR1|BUP1_HUMAN1.220e-17362.03Beta-ureidopropionase OS=Homo sapiens OX=9606 GN=U... [more]
sp|Q03248|BUP1_RAT2.002e-17161.23Beta-ureidopropionase OS=Rattus norvegicus OX=1011... [more]
sp|Q8VC97|BUP1_MOUSE3.493e-17161.23Beta-ureidopropionase OS=Mus musculus OX=10090 GN=... [more]
sp|Q8H183|BUP1_ARATH3.839e-15459.79Beta-ureidopropionase OS=Arabidopsis thaliana OX=3... [more]
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BLAST of Beta-ureidopropionase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5E4MJY68.271e-17865.21Carbon-nitrogen hydrolase OS=Cinara cedri OX=50660... [more]
A0A0A9Z1K65.276e-17766.22Beta-ureidopropionase OS=Lygus hesperus OX=30085 G... [more]
A0A0K8T7L11.038e-17666.22CN hydrolase domain-containing protein OS=Lygus he... [more]
A0A0A9Z3V84.605e-17666.05Beta-ureidopropionase OS=Lygus hesperus OX=30085 G... [more]
T2M4E15.060e-17563.71Beta-ureidopropionase (Fragment) OS=Hydra vulgaris... [more]
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BLAST of Beta-ureidopropionase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
upb11.686e-16358.02beta-ureidopropionase 1 [Source:NCBI gene;Acc:1030... [more]
nit12.887e-824.79nitrilase 1 [Source:NCBI gene;Acc:103037987][more]
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BLAST of Beta-ureidopropionase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000008167.18.681e-6547.85pep scaffold:Pmarinus_7.0:GL477981:1516:9010:-1 ge... [more]
ENSPMAT00000006563.15.980e-5273.21pep scaffold:Pmarinus_7.0:GL482671:2818:12612:-1 g... [more]
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BLAST of Beta-ureidopropionase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
NIT33.295e-1324.28Nit protein; one of two proteins in S. cerevisiae ... [more]
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BLAST of Beta-ureidopropionase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO373522.908e-12049.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO307091.869e-1323.67Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO273949.095e-1032.28Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO472069.304e-923.90Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Beta-ureidopropionase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
upb13.748e-16359.68beta-ureidopropionase 1 [Source:NCBI gene;Acc:1011... [more]
nit23.919e-1121.17nitrilase family member 2 [Source:NCBI gene;Acc:10... [more]
nit29.569e-1125.00nitrilase family member 2 [Source:NCBI gene;Acc:10... [more]
nit16.656e-826.42nitrilase 1 [Source:NCBI gene;Acc:101174868][more]
nit16.969e-826.42nitrilase 1 [Source:NCBI gene;Acc:101174868][more]
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BLAST of Beta-ureidopropionase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000060425.10.000e+099.73SMESG000060425.1[more]
SMESG000071423.12.956e-1025.91SMESG000071423.1[more]
SMESG000071423.13.479e-1026.87SMESG000071423.1[more]
SMESG000071423.13.644e-1026.87SMESG000071423.1[more]
SMESG000071424.15.346e-931.25SMESG000071424.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30009913 ID=SMED30009913|Name=Beta-ureidopropionase|organism=Schmidtea mediterranea sexual|type=transcript|length=1469bp
TCTGCATAAACAGGGAATGAATAATCAGTGTATTCGTGTCAACGCATTTG
TGCACCACTTAAAATAGTGCACTTTGTTATTTATCATTGCAATATTAATT
GTTTTTATTAATATATATTTTTGATTTTATCAATCACAATTCATTCTACC
GGATCAAAAATGGCAAAAAAATCCATTGAAAGCCTTGAAAAGATACTGTT
GACACTTGGTGATAATGAGGATCTTGAATATGTTACGAAATTGCTTTATG
GAAAATCTCTGGAAACAATAAATATTGATGAAAATGCTGTCAATGATGCT
AAACAACTAAATATCGATTTACAGGGTTTTAGATTTTTAGCGAAATCCGA
ATCTACGAGAATTCCACAGATAGTTCGTGTTGGAGCTATTCAAAATCAAA
TTGTGCTGGGAGCATCTGAACCCGTTAGTGATCAGATTCTAGCTCTCCAT
GATCGGATAAAAAAAATTATTGATTTAGCGGGTAAATTGAAAGTAAACAT
AATATGTTTACAAGAAGCATGGACGATGCCATTTGGATTCTGTACCAGAG
AAAAGTTGCCATGGTGTGAATTTGCTGAAAGAATTCCTGAAGGTTTAACG
ACGCAATTTCTATGCAAGTTAGCGAAAACTCACTCAATGGTCATAATTTC
TCCGATATTGGAAAGAGACAAAAGAGATGTAATCTGGAATACAGCAGTAA
TTATTGACCAAAATGGAAATTTCCTTGGAAAATCGCGAAAAAATCATATT
CCCAGAGTTGGAGATTTTAATGAATCAACTTATTATATGGAAGGAAATCT
TGGTCATCCGGTTTTCGACACCATTTATGGTAAGATTGCTGTTAATATAT
GTTTCGGTCGTCACCAACCTCTAAATTGGCTTGTTTATGGTCTAGAAGGG
GCACAAATTGTGTTTAACCCATCTGCAACTGTTGACGGTTTAAGTGAAAC
ATTGTGGCCAATTGAAGCTAGAAATGCTGCTATTGCTAATCACTATTTCA
CAGTAGCAATCAATCGTGTCGGAACAGAGGTGTTTCCTCATGATTTCACA
TCAGGAGATGGTAAACAACCTCATAAGGAGTTTGGTCATTTTTATGGATC
TTCGTACATAACGGCACCAGATGGATCAAGAACTAAGGGTCTCAGTCGCG
TGCAAGATGGATTGTTGATTGCTGAAATGGATTTGAATTTATGCCGACAA
ATCAAGGATGAATGGGGATTTTCAATGACACAAAGGCTCGAAATGTATGC
AAAGAAGCTGCAGGAATTTGTTGAAAAATTTGAAAATTAGGAATCCCATT
GTGATTTATAGAAACCTACAATATATTGAATATTAATATTTTTATATTAT
TTAAATTGAGCTTTGCTTATATATTTTTAATTCAATCTTTGTGTAAGATT
AATATTTTTAATTATTAAGTGCTAAATTTTGAAAATTTTTTGAGGTTGTC
CGAAATTGGAATGGGACCG
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protein sequence of SMED30009913-orf-1

>SMED30009913-orf-1 ID=SMED30009913-orf-1|Name=SMED30009913-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=377bp
MAKKSIESLEKILLTLGDNEDLEYVTKLLYGKSLETINIDENAVNDAKQL
NIDLQGFRFLAKSESTRIPQIVRVGAIQNQIVLGASEPVSDQILALHDRI
KKIIDLAGKLKVNIICLQEAWTMPFGFCTREKLPWCEFAERIPEGLTTQF
LCKLAKTHSMVIISPILERDKRDVIWNTAVIIDQNGNFLGKSRKNHIPRV
GDFNESTYYMEGNLGHPVFDTIYGKIAVNICFGRHQPLNWLVYGLEGAQI
VFNPSATVDGLSETLWPIEARNAAIANHYFTVAINRVGTEVFPHDFTSGD
GKQPHKEFGHFYGSSYITAPDGSRTKGLSRVQDGLLIAEMDLNLCRQIKD
EWGFSMTQRLEMYAKKLQEFVEKFEN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0033396beta-alanine biosynthetic process via 3-ureidopropionate
GO:0046135pyrimidine nucleoside catabolic process
GO:0051260protein homooligomerization
GO:0006807nitrogen compound metabolic process
GO:0008152metabolic process
GO:0019483beta-alanine biosynthetic process
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0002032epidermal cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR036526C-N_Hydrolase_sf
IPR003010C-N_Hydrolase
Vocabulary: molecular function
TermDefinition
GO:0016810hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0003824catalytic activity
GO:0003837beta-ureidopropionase activity
GO:0016787hydrolase activity
GO:0046872metal ion binding
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003010Carbon-nitrogen hydrolasePFAMPF00795CN_hydrolasecoord: 73..349
e-value: 3.4E-55
score: 187.2
IPR003010Carbon-nitrogen hydrolasePROSITEPS50263CN_HYDROLASEcoord: 72..342
score: 51.419
IPR036526Carbon-nitrogen hydrolase superfamilyGENE3DG3DSA:3.60.110.10coord: 1..374
e-value: 4.4E-144
score: 482.1
IPR036526Carbon-nitrogen hydrolase superfamilySUPERFAMILYSSF56317Carbon-nitrogen hydrolasecoord: 71..363
NoneNo IPR availablePANTHERPTHR43674:SF2BETA-UREIDOPROPIONASEcoord: 5..372
NoneNo IPR availablePANTHERPTHR43674FAMILY NOT NAMEDcoord: 5..372